Details of the Drug

General Information of Drug (ID: DMF2CZ9)

Drug Name
OSI-930
Synonyms OSI 930; OSI930; OSI-930 is a multi-targeted tyrosine kinase inhibitor; 3-(quinolin-4-ylmethylamino)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxamide
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 443.4
Logarithm of the Partition Coefficient (xlogp) 6.2
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C22H16F3N3O2S
IUPAC Name
3-(quinolin-4-ylmethylamino)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxamide
Canonical SMILES
C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
InChI
InChI=1S/C22H16F3N3O2S/c23-22(24,25)30-16-7-5-15(6-8-16)28-21(29)20-19(10-12-31-20)27-13-14-9-11-26-18-4-2-1-3-17(14)18/h1-12,27H,13H2,(H,28,29)
InChIKey
FGTCROZDHDSNIO-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
9868037
ChEBI ID
CHEBI:91433
CAS Number
728033-96-3
UNII
G1PEG5Q9Y2
DrugBank ID
DB05913
TTD ID
D0N8RV
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tyrosine-protein kinase Kit (KIT) TTX41N9 KIT_HUMAN Modulator [1]
Vascular endothelial growth factor receptor 2 (KDR) TTUTJGQ VGFR2_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tyrosine-protein kinase Kit (KIT) DTT KIT 2.06E-01 -0.1 -0.14
Vascular endothelial growth factor receptor 2 (KDR) DTT KDR 1.98E-01 0.11 0.2
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 4.5688 7.6287 2.1262 6.0638
ES1 GDSC1 2.1464 3.3447 2.039 15.8263
ES5 GDSC1 2.5003 5.9645 1.2845 19.5158
SK-ES-1 GDSC1; CTRP2 2.822 4.4061 2.8056 21.523
EW-7 GDSC1 3.3111 4.3886 2.8019 4.5366
NOS-1 [Human HNSCC] GDSC1 3.4138 8.3271 0.9186 18.2653
ES4 GDSC1 3.4865 5.4092 2.4361 6.7964
ES7 GDSC1 3.491 8.2234 1.034 17.2221
EW-13 GDSC1 3.5486 4.8303 2.7727 3.9501
EW-18 GDSC1 3.6161 5.138 2.6715 4.5281
TC-71 GDSC1 3.6169 7.3249 1.5847 12.8977
EW-1 GDSC1 3.6758 5.5847 2.4958 5.7116
MHH-ES-1 GDSC1; CTRP2 3.9769 5.6723 3.8777 14.1149
ES8 GDSC1 3.992 7.165 1.9522 8.9265
HuO9 GDSC1 4.0631 6.7718 2.1956 6.8741
EW-16 GDSC1 4.142 6.9565 2.1614 6.9114
EW-24 GDSC1 4.1767 7.1887 2.0731 7.4776
EW-11 GDSC1 4.5369 9.6606 1.1255 13.1862
A-673 GDSC1 4.5965 10.3848 0.8142 15.0052
ES6 GDSC1 4.7591 11.3298 0.4695 16.5834
HOS GDSC1 4.8982 9.8028 1.3097 10.9497
SK-PN-DW GDSC1 5.0309 8.3264 2.0891 5.2801
U2OS GDSC1 5.1298 7.4186 2.5433 2.1782
SJSA-1 GDSC1; CTRP2 5.1323 7.1636 4.6173 8.0279
HuO-3N1 GDSC1 5.3138 10.0442 1.4688 8.8461
CADO-ES1 GDSC1 5.3194 6.7761 2.8797 0.4182
SaOS-2 GDSC1; CTRP2 5.3371 7.1226 4.8427 6.6058
NY GDSC1 5.3444 8.5846 2.1539 4.2349
CAL-72 GDSC1 5.5144 7.4712 2.7003 0.9449
CAL-78 GDSC1; CTRP2 5.6199 8.1529 4.6184 6.8671
CHSA8926 GDSC1 5.6904 8.1498 2.5128 1.6373
G-292 clone A141B1 GDSC1; CTRP2 5.8775 12.418 2.7175 14.1746
CHSA0108 GDSC1 5.9503 8.5407 2.4754 1.5461
CHSA0011 GDSC1 6.1318 8.6168 2.5246 1.1645
Hs 888.T CTRP2 6.133 7.4127 5.4326 2.4056
Hs 822.T CTRP2 6.3116 9.8657 4.3516 6.6155
H-EMC-SS GDSC1 6.4572 9.1488 2.4593 1.1702
EW-3 GDSC1 6.8193 8.7986 2.7222 0.2383
MG-63 GDSC1; CTRP2 8.0533 10.5696 5.1556 1.2177
SW1353 CTRP2 8.249 9.9833 5.4735 0.3125
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 191 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 1.7679 4.1393 1.7277 28.6255
JM1 GDSC1 3.6562 5.2093 2.6662 4.4462
Kasumi-1 GDSC1 -5.6044 3.9534 -6.5922 74.5066
EoL-1 GDSC1 -4.8439 26.753 -15.7226 57.2048
GDM-1 GDSC1; CTRP2 0.1147 3.5003 0.0504 39.6925
MOLM-13 GDSC1; CTRP2 0.6758 4.172 0.5704 36.0984
NKM-1 GDSC1 0.6821 4.1014 0.2051 36.01
WIL2 NS GDSC1 0.9535 3.4022 0.7214 31.4676
SKM-1 CTRP2 1.0216 3.4657 0.9976 33.542
SU-DHL-16 GDSC1 1.246 4.1382 0.8007 29.2079
EB2 GDSC1 1.2697 7.219 -0.5043 35.3416
Peer CTRP2 1.3777 2.7237 1.3771 31.0924
SIG-M5 GDSC1 1.556 3.1561 1.4423 23.2382
NCO2 CTRP2 1.5851 3.4729 1.5756 29.7404
REC-1 CTRP2 1.7573 6.0248 1.3711 29.8597
CML-T1 CTRP2 1.8481 3.8638 1.8293 28.0192
P31/FUJ GDSC1; CTRP2 1.9601 3.3007 1.9586 27.2151
MV4-11 GDSC1; CTRP2 1.9762 3.9821 1.9553 27.1727
KMS-34 CTRP2 1.9955 4.1401 1.9652 27.0759
Ku812 GDSC1; CTRP2 1.9962 3.0794 1.9959 26.9705
BL-41 GDSC1 2.0056 6.9244 0.3511 27.6919
KE-97 CTRP2 2.0655 6.1824 1.6636 27.8839
ALL-SIL GDSC1 2.0694 4.495 1.5345 19.7967
CTV-1 GDSC1 2.087 5.6928 1.014 23.3108
CESS GDSC1 2.1072 3.2987 2.0084 16.2573
BV-173 GDSC1; CTRP2 2.1225 4.007 2.1049 26.1873
MOLM-6 CTRP2 2.1358 4.4544 2.0851 26.2104
Daudi GDSC1 2.1452 3.7798 1.8987 16.8034
KMS-21-BM CTRP2 2.1568 3.5288 2.1544 25.9077
M-07e CTRP2 2.2228 4.7842 2.1381 25.7466
LAMA-84 GDSC1; CTRP2 2.2682 4.1319 2.2487 25.2227
SUP-T11 CTRP2 2.307 3.9667 2.2963 24.9348
JURL-MK1 GDSC1; CTRP2 2.3137 3.4602 2.3129 24.8572
NU-DHL-1 CTRP2 2.3506 3.3164 2.3504 24.6093
AML-193 CTRP2 2.3686 5.7492 2.1095 25.3817
Jurkat CTRP2 2.3795 3.8102 2.3748 24.4319
Ri-1 CTRP2 2.414 5.2614 2.2654 24.694
RPMI-8402 GDSC1; CTRP2 2.4277 4.3203 2.4022 24.1805
EM-2 GDSC1; CTRP2 2.468 4.1669 2.453 23.8765
MEG-01 GDSC1 2.4757 4.6049 1.9028 15.0999
SU-DHL-1 GDSC1; CTRP2 2.4808 3.5353 2.4802 23.7434
SU-DHL-5 GDSC1 2.4856 3.379 2.3998 11.446
KYO-1 CTRP2 2.5023 5.0723 2.3942 23.9661
NALM-6 GDSC1 2.5259 4.4135 2.0399 13.8372
Ki-JK CTRP2 2.5425 8.6148 1.3077 27.6149
KMS-20 CTRP2 2.5589 7.7824 1.6566 26.3864
KMS-12-BM GDSC1; CTRP2 2.6187 4.9446 2.5386 23.0941
ME1 CTRP2 2.6201 4.4428 2.5937 22.9018
Farage GDSC1 2.6926 3.7931 2.479 9.7706
SUP-T1 GDSC1; CTRP2 2.6928 15.4872 -1.6958 34.725
MOLT-16 GDSC1; CTRP2 2.7 4.2241 2.6889 22.3179
P12-Ichikawa GDSC1; CTRP2 2.7502 5.2553 2.63 22.3571
K-562 GDSC1 2.7771 4.2921 2.3479 10.3315
L-540 GDSC1; CTRP2 2.8033 4.1371 2.7975 21.612
Mono-Mac-1 CTRP2 2.8043 4.6465 2.7699 21.7016
SUP-HD1 GDSC1 2.8056 4.2127 2.4128 9.7069
KE-37 GDSC1; CTRP2 2.8295 4.0224 2.8266 21.4278
LP-1 GDSC1 2.8347 4.0403 2.5204 8.7594
KM-H2 GDSC1; CTRP2 2.8595 5.4162 2.7178 21.7045
KCL-22 GDSC1; CTRP2 2.8596 5.0958 2.7742 21.5081
OCI-Ly19 GDSC1 2.8631 3.609 2.7328 7.0552
KOPN-8 GDSC1 2.8954 4.7383 2.2515 10.5365
OCI-AML-2 GDSC1; CTRP2 2.9106 5.2376 2.806 21.2348
RPMI-6666 GDSC1 2.9197 8.5458 0.3892 23.4026
HH [Human lymphoma] GDSC1 2.926 5.2503 2.0304 12.1149
HPB-ALL CTRP2 2.9302 4.9456 2.8707 20.9486
NB4 GDSC1; CTRP2 2.9398 4.0829 2.9372 20.692
SUP-B15 GDSC1 2.962 4.007 2.6635 7.0799
Ci-1 CTRP2 2.9823 5.4972 2.8346 20.9077
HT GDSC1; CTRP2 2.9828 4.1737 2.979 20.4095
OCI-AML-3 GDSC1 2.9876 5.1698 2.1264 11.1152
MHH-CALL-4 CTRP2 2.9921 5.2208 2.8967 20.66
Karpas-231 GDSC1 3.0023 3.7629 2.8146 5.7533
RCH-ACV CTRP2 3.0071 5.3777 2.8851 20.6527
SEM CTRP2 3.0175 4.3778 3.0082 20.1968
SU-DHL-8 GDSC1; CTRP2 3.0355 6.855 2.5083 21.9228
PL21 CTRP2 3.037 4.1801 3.0338 20.0465
TALL-1 [Human adult T-ALL] CTRP2 3.0585 5.4701 2.9227 20.3586
BE-13 GDSC1 3.0644 4.6354 2.4597 8.2022
A3/Kawakami GDSC1 3.0645 3.6331 2.9353 4.553
SUP-M2 GDSC1 3.0682 3.6633 2.926 4.6033
QIMR-WIL GDSC1 3.0859 4.2496 2.6681 6.4913
Sc-1 GDSC1 3.0954 4.6522 2.4798 7.9171
Mono-Mac-6 GDSC1; CTRP2 3.1231 5.6105 2.9634 20.0124
KMS-26 CTRP2 3.1382 4.3624 3.1322 19.3813
BC-1 GDSC1 3.1392 4.6732 2.5091 7.51
SU-DHL-10 GDSC1; CTRP2 3.1485 3.8054 3.1485 19.2929
MOLP-8 GDSC1 3.1584 3.9561 2.8788 4.5478
KG-1 GDSC1 3.1805 6.7091 1.5312 14.8887
KMS-27 CTRP2 3.2047 5.5893 3.0567 19.4281
MOLT-13 GDSC1; CTRP2 3.2117 4.4057 3.2058 18.8915
697 GDSC1 3.2329 4.8572 2.5006 7.2074
DEL GDSC1; CTRP2 3.2333 5.6958 2.8583 14.3765
HC-1 GDSC1 3.2543 4.4596 2.7175 5.4183
BALL-1 GDSC1 3.2832 4.9161 2.5146 6.9059
P30/OHK GDSC1 3.2888 4.9208 2.517 6.8661
CA46 GDSC1 3.2943 5.3703 2.2971 8.5767
KMS-11 GDSC1; CTRP2 3.3136 4.9623 3.2752 18.3224
KMS-18 CTRP2 3.3225 5.4823 3.2064 18.5319
Reh GDSC1; CTRP2 3.3292 4.5036 3.3226 18.1111
KMOE-2 GDSC1 3.332 4.4118 2.8081 4.4104
ALL-PO GDSC1 3.3394 5.1698 2.4353 7.3227
NU-DUL-1 GDSC1; CTRP2 3.353 4.1743 3.3525 17.9322
ST486 GDSC1 3.3569 4.4016 2.8341 4.1146
TUR GDSC1 3.3749 4.9468 2.5764 6.0815
HL-60 GDSC1 3.3843 4.2202 2.9473 3.124
P32/ISH GDSC1 3.3886 5.5772 2.2725 8.4251
WSU-DLCL2 GDSC1 3.4005 5.063 2.5394 6.2823
U-698-M GDSC1 3.4443 4.7615 2.7255 4.6633
Karpas-45 GDSC1 3.4719 7.1007 1.5795 13.4473
SU-DHL-6 GDSC1; CTRP2 3.487 5.2601 3.4218 17.2592
ML-2 GDSC1 3.502 4.7094 2.7969 3.9095
JSC-1 GDSC1 3.5028 5.7115 2.2983 7.8229
HAL-01 GDSC1 3.5151 4.8305 2.7469 4.2597
ARH-77 GDSC1 3.5383 5.4302 2.4667 6.3817
RS4;11 GDSC1; CTRP2 3.5661 4.9394 3.5429 16.5888
THP-1 GDSC1 3.5669 6.2127 2.0995 9.1566
Hs 445 GDSC1 3.6096 4.8692 2.7991 3.5563
L-428 GDSC1; CTRP2 3.6261 6.0125 3.4139 16.8523
F-36P CTRP2 3.649 14.9846 -0.5509 29.8628
LC4-1 GDSC1 3.6539 5.4125 2.5643 5.2457
L-363 GDSC1; CTRP2 3.6917 5.0749 3.6625 15.7724
EJM GDSC1 3.727 5.1569 2.7429 3.6469
Namalwa GDSC1 3.7436 5.7653 2.4572 5.8025
GR-ST GDSC1 3.7573 6.5194 2.0951 8.5645
MHH-CALL-3 CTRP2 3.758 6.0825 3.5387 16.0005
HuT 78 CTRP2 3.7634 5.6084 3.6592 15.5543
MOLT-4 GDSC1 3.7893 5.6132 2.5651 4.8337
MHH-PREB-1 GDSC1 3.8062 5.4884 2.6378 4.2276
Kasumi-2 CTRP2 3.8331 5.6163 3.7331 15.0753
VAL GDSC1 3.852 7.9657 1.4505 13.0778
PL-21 GDSC1 3.8691 5.8529 2.5051 5.0653
PF-382 GDSC1; CTRP2 3.8733 6.6217 3.4956 15.8165
ME1 GDSC1 3.888 5.16 2.8496 2.4297
NCI-H929 CTRP2 3.8917 6.7228 3.4803 15.8205
OPM-2 GDSC1 3.9021 5.6565 2.623 4.078
JJN-3 GDSC1; CTRP2 3.903 5.6057 3.8109 14.5822
RPMI-8226 GDSC1; CTRP2 3.9147 6.0965 3.7058 14.9208
SR GDSC1; CTRP2 3.9792 5.9267 3.8216 14.307
MLMA GDSC1 3.9844 5.7968 2.6113 3.9502
KMS-28BM CTRP2 4.0007 5.4182 3.9486 13.7925
BC-3 GDSC1 4.0419 6.2591 2.4288 5.1692
JVM-2 GDSC1 4.0495 7.5979 1.7817 10.028
Raji GDSC1; CTRP2 4.0656 7.1619 3.5026 15.2435
Ramos.2G6.4C10 GDSC1 4.098 9.2443 1.0052 15.3298
CCRF-CEM GDSC1 4.0981 6.8631 2.1759 6.9251
WSU-NHL GDSC1 4.0988 6.0346 2.5737 3.9417
H9 GDSC1 4.1088 5.8813 2.6521 3.3449
DB GDSC1 4.1125 6.5796 2.3229 5.7772
HEL GDSC1; CTRP2 4.1247 7.8398 3.2855 15.9231
SK-MM-2 GDSC1; CTRP2 4.1278 5.2355 4.1058 12.8429
Loucy GDSC1 4.1459 5.568 2.8184 2.0925
Karpas-299 GDSC1; CTRP2 4.2806 6.5552 3.9593 12.9035
SU-DHL-4 GDSC1; CTRP2 4.3036 6.5877 3.9727 12.7871
Karpas-422 GDSC1 4.3267 6.8173 2.3521 5.0107
RPMI-8866 GDSC1 4.3448 8.9975 1.311 12.5061
KY821 GDSC1 4.3605 9.248 1.1996 13.2172
ATN-1 GDSC1 4.395 6.1373 2.7062 2.3674
Jiyoye GDSC1 4.4172 6.4691 2.5698 3.2491
YT GDSC1 4.4191 6.115 2.7294 2.1706
SCC-3 GDSC1 4.4591 7.9162 1.9169 7.8628
Granta-519 GDSC1 4.4901 7.2523 2.2525 5.3409
EHEB CTRP2 4.5068 10.011 2.669 17.387
TK [Human B-cell lymphoma] GDSC1 4.5963 6.4038 2.6996 2.0566
U266B1 GDSC1; CTRP2 4.7632 7.8694 3.9259 11.7309
A4/Fukuda GDSC1 4.7654 6.3971 2.7877 1.2966
RL GDSC1 4.7906 9.6309 1.3188 11.1787
CTB-1 GDSC1 4.9215 6.8858 2.6621 1.7886
NOMO-1 GDSC1; CTRP2 4.9774 7.1289 4.4737 8.9996
VL51 GDSC1 4.9861 6.9199 2.6796 1.6036
ROS-50 GDSC1 5.0653 7.3173 2.5533 2.2136
MN-60 GDSC1 5.1813 7.1953 2.6603 1.466
OCI-AML-5 GDSC1; CTRP2 5.2301 6.1111 5.1367 5.7541
DG-75 GDSC1 5.3152 10.2066 1.3935 9.3397
Karpas-620 GDSC1; CTRP2 5.3487 9.2597 3.8257 10.758
KMM-1 CTRP2 5.398 15.6493 0.6932 22.3742
RC-K8 GDSC1 5.4847 6.9968 2.8637 0.3816
HDLM-2 GDSC1; CTRP2 5.5041 10.768 3.2185 12.9258
L-1236 GDSC1 5.6017 7.9994 2.5322 1.6387
P3HR-1 CTRP2 5.6121 7.4335 4.9633 5.4534
DND-41 GDSC1; CTRP2 5.8998 8.2947 4.7966 5.531
MY-M12 GDSC1 5.9775 7.981 2.6987 0.6256
JVM-3 GDSC1; CTRP2 6.537 12.2922 3.3209 10.4847
MOLM-16 CTRP2 6.6381 8.7766 5.1359 2.8138
OCI-Ly10 CTRP2 6.9155 19.7124 -0.0779 21.6425
KHM-1B CTRP2 6.9667 10.6317 4.4665 5.0491
OCI-M1 GDSC1; CTRP2 7.4285 10.2183 4.967 2.4515
AMO1 GDSC1; CTRP2 7.6764 13.2789 3.6804 7.1689
HD-MY-Z CTRP2 7.7244 14.6509 3.0482 9.5928
MOLP-2 CTRP2 8.2656 10.8192 5.1559 1.068
MC116 GDSC1; CTRP2 8.6025 15.7607 3.1171 8.0559
⏷ Show the Full List of 191 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 4.3062 6.0762 4.1387 12.1672
TE-6 GDSC1; CTRP2 3.864 5.7851 3.7303 14.9885
TE-15 GDSC1 4.1782 10.7946 0.2978 19.3438
TE-8 GDSC1 4.4676 7.2564 2.2362 5.5128
KYSE-140 GDSC1; CTRP2 4.624 7.5027 3.9471 12.0057
TE-4 GDSC1; CTRP2 4.6719 6.4011 4.4359 9.9887
T.T GDSC1 4.6781 6.7629 2.5874 2.6295
TE-11 GDSC1 4.7691 7.1594 2.463 3.2783
EC-GI-10 GDSC1 4.8708 7.0805 2.5533 2.5169
KYSE-270 GDSC1 5.1625 7.1242 2.6801 1.3858
OE21 GDSC1 5.1859 7.432 2.5656 1.9722
TE-5 GDSC1 5.1947 7.1663 2.6781 1.3596
COLO 680N GDSC1; CTRP2 5.2217 8.1881 4.2281 9.386
TE-10 GDSC1; CTRP2 5.4822 9.1587 3.3397 6.8157
KYSE-410 GDSC1; CTRP2 5.4823 7.5301 4.7934 6.4543
KYSE-510 GDSC1; CTRP2 5.5022 11.4328 2.886 14.2763
KYSE-180 GDSC1; CTRP2 5.7033 8.2943 4.6239 6.6638
KYSE-30 CTRP2 5.7399 8.093 4.7565 6.0314
TE-9 GDSC1; CTRP2 5.867 9.135 2.8472 3.0088
KYSE-150 GDSC1; CTRP2 6.0103 13.4572 2.3095 15.4945
TE-14 CTRP2 6.0124 9.9595 4.0602 8.3995
TE-1 GDSC1; CTRP2 6.9759 14.658 2.4871 13.0059
OE33 GDSC1; CTRP2 7.3282 9.6613 5.1607 1.8477
OE19 GDSC1; CTRP2 7.848 9.1472 5.6207 0.1823
KYSE-450 GDSC1; CTRP2 7.8927 9.5619 5.4852 0.4258
KYSE-520 GDSC1; CTRP2 8.1657 11.1813 4.9541 1.7669
KYSE-70 GDSC1; CTRP2 8.8187 10.3094 5.5685 0.0751
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 8.6968 13.4224 4.2612 3.6594
L3.3 CTRP2 0.5499 4.0205 0.4553 36.8995
MZ-PC-1 GDSC1 3.3112 5.1648 2.4141 7.5926
HuP-T4 GDSC1; CTRP2 3.4437 7.5952 2.6714 20.142
PSN1 GDSC1 3.5768 5.4452 2.4893 6.077
Panc 03.27 GDSC1 3.741 5.3499 2.659 4.2514
KP-4 GDSC1; CTRP2 4.1044 6.7343 3.3287 9.9186
BxPC-3 GDSC1; CTRP2 4.5665 8.3488 3.5098 13.8936
SU.86.86 GDSC1 4.6135 7.0629 2.4162 3.9043
PL4 GDSC1 4.8473 8.3479 1.9665 6.5384
PK-59 CTRP2 5.0946 10.6135 2.927 14.9981
MIA PaCa-2 GDSC1 5.3041 11.0302 0.9959 11.9208
SNU-410 CTRP2 5.3656 7.6681 4.6152 7.46
Panc 10.05 GDSC1; CTRP2 5.4273 8.2077 4.4135 8.1473
KP-3 GDSC1; CTRP2 5.4843 8.9879 4.0833 9.391
Panc 08.13 GDSC1; CTRP2 5.5488 8.6541 4.3065 8.3212
Capan-2 GDSC1; CTRP2 5.844 9.2588 4.2672 7.8653
Hs 766T GDSC1; CTRP2 6.441 7.9794 5.3842 2.0966
CFPAC-1 GDSC1; CTRP2 6.8772 12.8493 3.3086 9.936
QGP-1 GDSC1; CTRP2 7.2308 12.2533 3.8646 7.098
SUIT-2 GDSC1; CTRP2 7.2947 12.5066 3.7867 7.3148
SNU-213 CTRP2 7.3599 18.1047 1.0724 17.3576
PaTu 8988t GDSC1; CTRP2 7.4918 8.5882 5.685 0.1779
HPAC GDSC1; CTRP2 7.5866 15.1973 2.6809 11.2321
Panc 04.03 GDSC1; CTRP2 7.7906 11.4171 4.6362 3.2763
HuP-T3 GDSC1; CTRP2 7.8305 13.2235 3.8121 6.4265
AsPC-1 GDSC1; CTRP2 7.9542 11.3091 4.7818 2.5607
YAPC GDSC1; CTRP2 8.0194 9.4558 5.5755 0.2073
KP-2 GDSC1; CTRP2 8.0436 9.4154 5.5991 0.1658
Panc 05.04 CTRP2 8.0582 14.4316 3.3872 7.7736
PaTu 8902 GDSC1; CTRP2 8.065 14.7449 3.2412 8.332
Panc 02.03 GDSC1; CTRP2 8.1811 12.9885 4.1503 4.6531
Capan-1 GDSC1; CTRP2 8.2039 9.8939 5.4884 0.3003
TCC-Pan2 CTRP2 8.2832 9.73 5.5771 0.144
PK-45H CTRP2 8.3112 15.0378 3.2677 7.881
SW1990 GDSC1; CTRP2 8.3605 11.9668 4.7179 2.386
PaTu 8988s CTRP2 8.4196 10.5276 5.3399 0.5161
HPAF-II GDSC1; CTRP2 9.2199 11.3491 5.3546 0.2392
DAN-G GDSC1; CTRP2 9.65 18.4933 2.507 8.9182
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 74 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.5453 9.3365 3.9826 2.4262
A-431 GDSC1 3.1377 6.2993 1.6988 13.8037
LB2518-MEL GDSC1 3.3999 4.9308 2.605 5.7673
G-mel GDSC1 3.4964 6.2916 2.0036 10.1434
WM115 GDSC1 3.7512 12.0322 -0.6572 25.4271
A2058 GDSC1 3.9227 5.3069 2.8028 2.6879
RPMI-7951 GDSC1; CTRP2 3.9381 5.8467 3.7965 14.5235
Hs 944.T CTRP2 3.9521 5.9708 3.7807 14.5367
WM35 GDSC1 3.9655 8.715 1.166 14.6892
WM1552C GDSC1 4.0527 6.6589 2.2431 6.5441
HMV-II GDSC1 4.0727 6.8743 2.1525 7.1734
MZ-MEL-7 GDSC1 4.2503 6.4803 2.4616 4.3958
LB373-MEL-D GDSC1 4.2925 8.9283 1.3067 12.6933
CP66-MEL GDSC1 4.3484 7.4769 2.0526 7.1621
CP50-MEL-B GDSC1 4.4073 6.8294 2.3978 4.4876
IST-MEL1 GDSC1 4.4332 9.3927 1.1816 13.1197
451Lu GDSC1 4.4747 6.6713 2.512 3.5304
VMRC-MELG GDSC1 4.5432 7.0712 2.37 4.3791
LOX-IMVI GDSC1 4.5448 7.564 2.1412 6.0138
Hs 938.T GDSC1 4.598 6.604 2.6131 2.6061
COLO 679 GDSC1 4.6482 7.2706 2.3421 4.3457
SH-4 GDSC1 4.7474 7.2598 2.4056 3.7045
DJM-1 GDSC1 4.7973 10.518 0.8936 13.9273
A-388 GDSC1 4.8565 8.3536 1.9697 6.4947
GAK GDSC1 4.8747 7.301 2.4593 3.1083
SK-MEL-1 GDSC1; CTRP2 4.8989 6.8982 4.4897 9.1465
MMAc-SF GDSC1 4.9343 11.8854 0.3245 16.8942
MZ-MEL-2 GDSC1 4.9747 13.4721 -0.4245 20.5813
COLO 783 GDSC1 5.1829 6.9592 2.7547 1.0033
M14 GDSC1 5.2744 7.0228 2.7696 0.8549
COLO 741 CTRP2 5.4401 8.5092 3.6297 5.5978
CHL-1 GDSC1 5.4651 11.6211 0.8215 12.5818
WM278 GDSC1 5.4958 9.0214 2.0453 4.6562
Malme-3M CTRP2 5.6838 12.6514 2.4358 15.6717
Mel Ho GDSC1; CTRP2 5.7188 10.1959 3.6914 10.5273
Hs 934.T CTRP2 5.7852 10.068 3.8127 9.8865
Mel JuSo GDSC1; CTRP2 5.9097 9.6193 4.1435 8.2523
IGR-37 GDSC1; CTRP2 6.0682 7.075 5.5488 2.0376
SK-MEL-30 GDSC1; CTRP2 6.1989 10.8598 3.7642 9.2794
Hs 940.T GDSC1; CTRP2 6.2824 9.7957 4.3633 6.6194
G-361 GDSC1; CTRP2 6.4511 12.0362 3.3803 10.398
Hs 688(A).T CTRP2 6.7551 11.1517 4.0561 7.077
WM1799 CTRP2 6.8571 15.8654 1.7937 15.7894
SK-MEL-28 GDSC1; CTRP2 7.0424 8.2938 5.6023 0.6066
K029AX CTRP2 7.0787 9.4419 5.1108 2.3194
COLO 800 GDSC1; CTRP2 7.2299 11.8772 4.0472 6.3576
SK-MEL-5 GDSC1; CTRP2 7.2937 12.8252 3.6304 7.9487
CJM [Human melanoma] CTRP2 7.3764 10.3065 4.8946 2.7859
UACC-257 GDSC1; CTRP2 7.425 11.109 4.5496 4.0642
SK-MEL-2 GDSC1; CTRP2 7.558 8.6924 5.6729 0.1787
UACC-62 GDSC1; CTRP2 7.5597 13.3355 3.5714 7.7765
IPC-298 GDSC1; CTRP2 7.5689 12.5563 3.9547 6.2303
COLO 829 GDSC1; CTRP2 7.6576 10.7187 4.8755 2.5354
A101D GDSC1; CTRP2 7.72 8.991 5.6277 0.2071
Hs 839.T CTRP2 7.7228 8.9793 5.633 0.1973
SK-MEL-31 CTRP2 7.7505 9.1062 5.5976 0.251
SK-MEL-24 GDSC1; CTRP2 7.8262 12.6056 4.1034 5.286
COLO 792 GDSC1; CTRP2 7.8332 11.0937 4.8087 2.5903
SK-MEL-3 GDSC1; CTRP2 7.8665 9.6501 5.4398 0.5448
Hs 895.T CTRP2 7.9008 12.9635 3.9827 5.6596
Hs 852.T CTRP2 8.0606 9.5703 5.5501 0.2371
IGR-39 CTRP2 8.1545 9.5811 5.5819 0.1645
MDA-MB-435S CTRP2 8.2279 15.6081 2.9373 9.2656
IGR-1 GDSC1; CTRP2 8.4199 15.6093 3.0674 8.4957
HT-144 GDSC1; CTRP2 8.4642 13.9263 3.8912 5.2928
MeWo GDSC1; CTRP2 8.4966 14.7725 3.5156 6.6813
A-375 GDSC1; CTRP2 8.5054 18.2155 1.8679 12.7767
WM793 GDSC1; CTRP2 8.7011 15.1973 3.4473 6.6775
WM983B CTRP2 8.8812 11.331 5.2286 0.5615
Hs 936.T CTRP2 9.2922 16.7867 3.0784 7.3085
WM88 CTRP2 9.3434 16.7253 3.1389 7.0247
WT2-iPS GDSC1; CTRP2 9.3945 16.2958 3.3685 6.1289
RVH-421 GDSC1; CTRP2 10.1791 17.7518 3.1719 5.9582
EquiPSC Line K2 GDSC1 5.7457 8.2548 2.4963 1.6588
⏷ Show the Full List of 74 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC1 3.7154 8.5598 1.0474 16.3335
TE-12 GDSC1 3.7548 6.332 2.186 7.8701
ESO-51 GDSC1 4.7781 6.975 2.5492 2.6998
HCE-4 GDSC1 4.9714 8.5361 1.9566 6.3226
KYAE-1 GDSC1 4.9753 6.9954 2.6431 1.8221
KYSE-220 GDSC1 5.5001 7.4259 2.7114 0.9103
FLO-1 GDSC1 5.8235 8.1666 2.5655 1.2562
ESO-26 GDSC1 6.0929 7.6894 2.8442 0.2077
SK-GT-4 GDSC1 6.1613 8.1286 2.7162 0.4775
OACM5.1 C GDSC1 6.6851 8.8383 2.6606 0.4033
OACP4 C GDSC1 6.7769 8.4367 2.8285 0.1014
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 5.7907 8.0618 2.5918 1.1704
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SiMa GDSC1; CTRP2 3.0288 5.021 2.9659 20.3035
SJNB-7 GDSC1 3.0311 3.7952 2.8296 5.5025
Kelly GDSC1; CTRP2 3.4046 4.8539 3.381 17.666
KP-N-YS GDSC1 3.4322 5.056 2.5688 5.9393
SJNB-12 GDSC1 3.5069 5.0077 2.6524 5.0276
SJNB-13 GDSC1 3.508 5.7827 2.267 8.0506
SJNB-17 GDSC1 3.6256 8.6608 0.9249 17.4546
SK-N-BE(2) CTRP2 3.7255 7.918 2.8367 18.7348
KP-N-SI9s CTRP2 3.8645 7.2194 3.2661 16.7078
GI-ME-N GDSC1 3.9885 6.9866 2.0371 8.2941
MHH-NB-11 GDSC1; CTRP2 4.0724 5.3415 4.0356 13.2625
NH-12 GDSC1 4.0786 6.7502 2.217 6.6693
IMR-5 GDSC1 4.0899 6.5452 2.3239 5.8301
SK-N-BE(2)-M17 GDSC1 4.0918 7.4427 1.8888 9.1032
SK-N-MC-IXC GDSC1 4.1881 5.6518 2.8051 2.0999
CHP-126 GDSC1; CTRP2 4.1961 5.5862 4.1314 12.5348
CHP-212 GDSC1 4.3517 7.0197 2.2728 5.5302
NB1 GDSC1; CTRP2 4.3786 7.2014 3.8182 13.1662
SJNB-10 GDSC1 4.5392 8.2014 1.8345 8.2481
SK-N-AS GDSC1 4.5947 8.2515 1.8479 8.0061
TGW GDSC1 4.6205 9.8444 1.0959 13.1378
SJNB-5 GDSC1 4.7543 10.527 0.8586 14.2685
SK-N-DZ GDSC1 4.7798 6.1528 2.8918 0.7619
NB(TU)1 GDSC1 4.8315 8.0918 2.0758 5.8073
CHP-134 GDSC1 5.1595 7.5987 2.4823 2.4937
SK-N-FI GDSC1 5.2036 7.2038 2.6672 1.4048
SK-N-SH GDSC1 5.2699 7.7309 2.4827 2.3284
GOTO GDSC1 5.3187 7.9452 2.4171 2.6414
SJNB-14 GDSC1 5.3632 7.0163 2.809 0.6312
KP-N-YN GDSC1; CTRP2 5.4103 9.4095 3.808 10.696
LA-N-6 GDSC1 5.6131 7.3998 2.7675 0.6145
SJNB-6 GDSC1 5.634 7.0619 2.896 0.2404
NB69 GDSC1 6.108 7.7949 2.8134 0.2628
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1196 CTRP2 4.3757 7.0466 3.8773 12.9461
HuCC-T1 GDSC1 4.6614 8.5983 1.7269 8.6965
SNU-308 CTRP2 5.0681 9.1407 3.6227 12.2282
SNU-478 CTRP2 6.8893 11.0947 4.1841 6.3289
SNU-869 CTRP2 7.8624 12.0024 4.4098 4.0508
HuH-28 CTRP2 8.2057 9.6773 5.567 0.1736
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 83 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUB-M GDSC1 2.7651 4.3092 2.328 10.5379
MDA-MB-468 GDSC1 3.3233 6.3872 1.8132 12.2306
BT-474 GDSC1 3.374 5.203 2.4475 7.1008
HCC1187 GDSC1 3.4763 6.7836 1.7415 12.2203
COLO 824 GDSC1 3.5045 5.1571 2.5761 5.6346
HMC-1-8 CTRP2 3.5519 5.9535 3.3485 17.3145
DU4475 GDSC1 3.6553 5.2539 2.6436 4.6243
MDA-MB-453 GDSC1; CTRP2 3.713 9.6586 2.0557 21.7193
MFM-223 GDSC1 3.7881 6.1246 2.3133 6.7815
MRK-nu-1 GDSC1 3.8186 5.2323 2.7699 3.1929
HCC2157 GDSC1 3.8916 6.2875 2.3092 6.5027
UACC-893 GDSC1 3.896 5.7998 2.5497 4.6501
MDA-MB-175-VII GDSC1 4.0334 6.6487 2.2344 6.6643
Evsa-T GDSC1 4.1727 6.7347 2.2894 5.8674
MDA-MB-415 GDSC1 4.2084 9.3241 1.0493 14.688
BT-483 GDSC1 4.2666 7.6833 1.8964 8.5406
HCC2218 GDSC1; CTRP2 4.4408 6.6229 4.1081 11.884
HCC1599 GDSC1 4.553 9.6931 1.1213 13.1666
AU565 GDSC1; CTRP2 4.5802 6.9804 4.1203 11.4464
MDA-MB-231 GDSC1; CTRP2 4.7964 8.8376 3.508 13.3357
MDA-MB-157 GDSC1; CTRP2 5.0203 7.0078 4.5702 8.5065
UACC-812 GDSC1 5.0205 6.772 2.7557 1.1641
CAL-120 GDSC1; CTRP2 5.0668 7.3314 4.4756 8.7607
EFM-192A GDSC1 5.0812 7.2055 2.6081 1.8753
HCC70 GDSC1 5.0918 6.7099 2.8116 0.8331
HCC1569 GDSC1 5.1314 7.8323 2.367 3.2493
JIMT-1 GDSC1; CTRP2 5.2723 9.7684 3.5054 12.2497
Hs 578T GDSC1 5.3065 7.8616 2.4462 2.4877
MDA-MB-436 GDSC1 5.3245 11.4962 0.7867 13.1516
MDA-MB-330 GDSC1 5.3621 9.1327 1.9189 5.7408
YMB-1-E GDSC1 5.4542 10.3983 1.3922 9.0204
CAL-51 GDSC1; CTRP2 5.4957 9.5126 3.8342 10.4022
MDA-MB-361 GDSC1; CTRP2 5.4961 10.6391 3.2755 12.7097
T-47D GDSC1; CTRP2 5.5822 9.6866 3.8251 10.2558
HCC1500 GDSC1; CTRP2 5.8171 11.4401 3.1548 12.539
EFM-19 GDSC1 5.8332 7.8472 2.6906 0.7434
Hs 578Bst CTRP2 5.8393 10.4407 3.6731 10.3585
HCC1428 GDSC1; CTRP2 6.1067 10.0425 4.0971 8.0632
CAL-148 GDSC1; CTRP2 6.1203 9.8614 4.1988 7.6108
HCC38 GDSC1 6.3135 8.2094 2.7441 0.3447
HCC1395 GDSC1; CTRP2 6.7976 9.2287 4.1695 1.4729
MCF-7 GDSC1; CTRP2 7.3055 12.8568 3.6234 7.9583
HCC202 CTRP2 7.3674 14.4199 2.9015 10.7347
HCC1806 GDSC1; CTRP2 7.8768 11.291 4.7451 2.7755
HDQ-P1 GDSC1; CTRP2 7.9115 12.4362 4.2382 4.6502
HCC1954 GDSC1; CTRP2 7.9707 9.6698 5.477 0.41
ZR-75-30 GDSC1; CTRP2 7.9834 14.9753 3.0734 9.1022
HCC1937 GDSC1; CTRP2 8.1332 12.0089 4.5706 3.1364
BT-549 GDSC1; CTRP2 8.4422 10.5225 5.3512 0.4823
CAMA-1 GDSC1; CTRP2 8.5082 15.8286 3.022 8.5451
HCC1143 CTRP2 8.804 14.7311 3.7287 5.4948
BT-20 GDSC1; CTRP2 9.3428 18.1543 2.4683 9.4532
CAL-85-1 GDSC1; CTRP2 9.5836 17.6627 2.8531 7.7667
HCC1419 GDSC1; CTRP2 9.6756 20.3305 1.6539 11.8265
BT 239 CTRP2 3.537 5.5124 3.4328 17.0618
BT 330 CTRP2 5.0825 8.1423 4.1156 10.1769
BT 416 CTRP2 5.1317 6.5717 4.8673 7.0494
BT 231 CTRP2 5.2428 9.2227 3.7462 11.3228
BT 245 CTRP2 5.2537 7.1516 4.7457 7.2053
BT 482 CTRP2 5.5968 9.017 4.1704 8.7847
BT 248 CTRP2 5.6061 13.9103 1.7405 18.4276
BT 139 CTRP2 5.6728 7.5043 4.9856 5.2238
BT 504 CTRP2 5.7247 7.7691 4.903 5.4527
BT 359 CTRP2 5.8582 8.0291 4.8929 5.2118
BT 286 CTRP2 5.8904 7.6981 5.0859 4.3361
BT 172 CTRP2 5.9116 7.2042 5.3504 3.1839
BT 159 CTRP2 6.0534 17.1613 0.4935 21.6315
BT 422 CTRP2 6.07 7.3889 5.3934 2.6873
BT 440 CTRP2 6.1018 7.7096 5.2591 3.1916
BT 216 CTRP2 6.1174 7.497 5.3781 2.663
BT 444 CTRP2 6.1373 7.6897 5.2978 2.9636
BT147 CTRP2 6.1966 7.1816 5.5971 1.6058
BT 232 CTRP2 6.2127 9.5283 4.4406 6.4229
BT 328 CTRP2 6.4827 9.2292 4.8009 4.4394
BT 131 CTRP2 6.505 8.4865 5.1827 2.8241
BT 340 CTRP2 6.5393 10.8368 4.0471 7.4828
BT 320 CTRP2 6.6428 7.8782 5.5652 1.1101
BT 228 CTRP2 6.8674 14.8516 2.3065 13.8852
BT 498 CTRP2 7.135 8.3852 5.6096 0.5201
BT 333 CTRP2 7.2246 16.3989 1.8148 15.057
BT 179 CTRP2 7.6214 9.0638 5.5603 0.3789
BT 187 CTRP2 8.1428 15.3902 2.9836 9.2127
BT 224 CTRP2 10.8138 18.7267 3.0985 5.5597
⏷ Show the Full List of 83 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.5724 8.6487 4.3 1.2211
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-247MG GDSC1 2.5849 4.2457 2.1745 12.5488
MOG-G-CCM GDSC1 3.7621 5.8351 2.4365 5.9068
H4 GDSC1 4.1994 5.9664 2.6688 3.0201
NMC-G1 GDSC1 4.3472 5.9238 2.7739 2.0104
D-263MG GDSC1 4.4132 7.7561 1.9626 7.6516
GI-1 GDSC1 4.4404 7.5794 2.0654 6.8266
KNS-60 CTRP2 4.4583 5.8686 4.3581 10.9137
D-542MG GDSC1 4.522 10.3563 0.7738 15.4782
D283 Med GDSC1 4.524 8.5089 1.6762 9.4256
SF268 GDSC1; CTRP2 4.5864 6.3309 4.3667 10.4955
Becker GDSC1 4.5986 8.6891 1.6406 9.4753
D-423MG GDSC1 4.6128 7.8685 2.0416 6.5658
DK-MG GDSC1 4.6304 20.1251 -3.9915 32.5349
Daoy GDSC1; CTRP2 4.6784 8.3238 3.6329 13.1202
SF539 GDSC1; CTRP2 4.7079 7.3515 4.0991 11.1856
PFSK-1 GDSC1 4.7244 7.1779 2.4292 3.5908
MOG-G-UVW GDSC1 4.7622 7.2252 2.4297 3.5131
D-566MG GDSC1 4.7658 7.5875 2.2679 4.611
LNZTA3WT4 GDSC1 4.8793 8.2139 2.0488 5.8888
ONS-76 GDSC1; CTRP2 4.8812 7.4621 4.2287 10.2209
KNS-81-FD GDSC1 4.955 9.094 1.6852 8.2443
LN-18 GDSC1; CTRP2 5.0237 5.966 4.5663 2.1964
Onda 11 GDSC1 5.0745 10.3492 1.1673 11.4228
CAS-1 GDSC1; CTRP2 5.1157 7.7442 4.3352 9.2038
LN-405 GDSC1 5.1316 14.4189 -0.7744 21.6958
D-336MG GDSC1 5.1547 8.3416 2.1548 4.5866
D-502MG GDSC1 5.161 7.6046 2.4806 2.5013
SK-MG-1 GDSC1 5.2108 7.4832 2.5566 1.9891
SF126 GDSC1; CTRP2 5.3117 8.9775 3.93 10.4088
Onda 10 GDSC1 5.3914 7.8374 2.4985 2.072
GB-1 GDSC1; CTRP2 5.4376 8.8466 4.1102 9.3817
D-392MG GDSC1 5.4557 12.8021 0.2478 15.8839
KS-1 [Human Krukenberg tumour] GDSC1 5.4711 7.8018 2.551 1.6918
SW1783 GDSC1; CTRP2 5.5257 12.0094 2.6193 15.2859
M059J GDSC1 5.5843 7.569 2.6925 0.9196
U-251MG GDSC1; CTRP2 5.6418 8.043 4.6925 6.5107
YH-13 GDSC1 5.6855 7.2105 2.8631 0.2973
DBTRG-05MG GDSC1; CTRP2 5.7989 8.7848 4.4646 7.1298
KNS-81 CTRP2 5.8946 8.7883 4.5457 6.5947
KINGS-1 GDSC1 6.0548 9.7672 2.0221 3.8565
SNU-466 CTRP2 6.1195 11.6593 2.5846 8.9977
KG-1-C CTRP2 6.1377 7.2516 5.5167 2.0444
SNB-75 GDSC1; CTRP2 6.3608 8.8864 4.8777 4.3265
42-MG-BA GDSC1; CTRP2 6.4781 9.5057 4.6606 5.0314
AM-38 GDSC1; CTRP2 6.5085 9.0939 4.887 4.0393
SNU-738 CTRP2 6.5265 9.2021 4.8471 4.175
SNU-201 CTRP2 6.7499 24.285 -2.4949 27.6089
LN-229 GDSC1; CTRP2 7.1568 9.7736 4.1219 1.3324
KALS-1 GDSC1; CTRP2 7.2981 9.7459 5.1047 2.0859
SNU-626 CTRP2 7.4778 9.9017 5.1387 1.7724
U-118MG GDSC1; CTRP2 7.5838 13.7154 3.4038 8.4078
CCF-STTG1 CTRP2 7.6416 12.7537 3.9095 6.3068
Hs 683 GDSC1; CTRP2 7.728 13.9061 3.4129 8.154
U-87MG ATCC GDSC1; CTRP2 7.7324 8.9992 5.6295 0.2003
SF295 GDSC1; CTRP2 7.8276 9.0373 5.6521 0.1411
SNU-489 CTRP2 7.8561 9.0768 5.6487 0.1393
SNU-1105 CTRP2 7.9021 8.9506 5.7088 0.0641
YKG-1 GDSC1; CTRP2 7.9776 9.5319 5.5314 0.2969
GMS-10 CTRP2 8.0069 14.8408 3.1549 8.7518
GOS-3 CTRP2 8.2416 12.2617 4.5197 3.2057
SW1088 GDSC1; CTRP2 8.5444 15.4346 3.2337 7.6923
M059K CTRP2 8.6513 15.9794 3.0454 8.2604
GaMG GDSC1; CTRP2 8.6671 10.0699 5.5966 0.0694
8-MG-BA GDSC1; CTRP2 8.7301 14.7147 3.6906 5.7255
A-172 GDSC1; CTRP2 9.7157 19.4202 2.1128 10.2125
T98G GDSC1; CTRP2 10.4893 20.4178 2.1378 9.1599
KNS-42 GDSC1; CTRP2 11.4998 21.2639 2.3567 7.3127
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 4.7876 6.706 2.6701 1.9354
TGBC24TKB GDSC1 5.1369 8.4622 2.0902 5.0541
ETK-1 GDSC1 5.9794 8.1938 2.621 0.8996
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 0.7228 4.9546 0.4939 36.1551
HEC-265 CTRP2 1.4749 3.6709 1.4545 30.5107
HEC-151 CTRP2 2.3066 4.8208 2.2225 25.1869
HEC-1-A CTRP2 4.263 7.8715 3.4149 15.05
HEC-59 CTRP2 4.8245 8.7806 3.5624 13.0478
RL95-2 GDSC1 4.9868 9.0249 1.7382 7.8007
HEC-108 CTRP2 5.0975 7.6667 4.3533 9.1753
HEC-251 CTRP2 5.1073 8.7691 3.8395 11.2486
KLE GDSC1; CTRP2 5.1363 7.4447 4.4941 8.5109
MFE-280 GDSC1 5.2345 11.1588 0.8874 12.7732
AN3-CA GDSC1 5.2438 9.3731 1.7375 7.2095
MFE-296 GDSC1; CTRP2 5.5746 8.3481 4.4809 7.5385
MFE-319 GDSC1 5.5973 7.4235 2.7525 0.678
HEC-50B CTRP2 5.7279 9.8326 3.8805 9.7209
HEC-6 CTRP2 6.0408 9.8596 4.1338 8.0358
ESS-1 GDSC1; CTRP2 8.0037 12.4773 4.2772 4.3853
HEC-1-B CTRP2 8.1064 9.9449 5.4296 0.4551
EN GDSC1; CTRP2 8.4154 12.706 4.4206 3.3807
EFE-184 CTRP2 8.6899 12.766 4.5481 2.6603
Ishikawa (Heraklio) 02 ER- CTRP2 4.4085 6.3964 4.1519 11.814
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR10TKB CTRP2 3.6271 5.657 3.5012 16.538
KTCTL-21 GDSC1 4.329 7.8391 1.8646 8.6002
UO-31 GDSC1; CTRP2 4.4589 6.2509 4.2536 11.2895
KMRC-20 GDSC1; CTRP2 4.4612 5.9368 4.3448 10.9519
KTCTL-1M GDSC1 4.6749 7.321 2.3351 4.338
BFTC-909 GDSC1; CTRP2 4.7155 6.4002 4.4834 9.6847
RXF 393L GDSC1 4.7198 7.3061 2.3686 4.0122
SN12C GDSC1 4.7717 7.3122 2.3961 3.7207
A-498 GDSC1 4.9397 6.7413 2.7305 1.3872
KTCTL-195 GDSC1 4.9546 7.656 2.3469 3.6973
KTCTL-13 GDSC1 5.015 7.4064 2.4892 2.6791
KTCTL-140 GDSC1 5.13 7.6637 2.4392 2.801
KTCTL-26A GDSC1 5.1509 7.5971 2.4786 2.5292
LB996-RCC GDSC1 5.2747 7.8471 2.4361 2.5944
SW156 GDSC1 5.3533 9.1776 1.8933 5.9285
LB1047-RCC GDSC1 5.354 9.1655 1.8992 5.8879
NCC021 GDSC1 5.358 7.7462 2.5199 1.9979
786-O GDSC1; CTRP2 5.3846 8.887 4.0417 9.7832
LB2241-RCC GDSC1 5.5008 7.3245 2.7501 0.755
BB65-RCC GDSC1 5.7113 7.5782 2.741 0.6442
SW13 GDSC1 5.79 7.8266 2.6807 0.8095
A-704 GDSC1 5.848 7.8395 2.6994 0.7024
HA7-RCC GDSC1 6.1287 7.9982 2.7502 0.4012
KMRC-3 CTRP2 6.2714 9.1362 4.6834 5.2973
TUHR4TKB CTRP2 6.5313 10.7685 4.0748 7.3812
RCC10RGB GDSC1; CTRP2 6.6313 8.9468 5.0484 3.1803
TK-10 GDSC1 6.6784 9.3151 2.4873 0.9117
VMRC-RCW GDSC1; CTRP2 7.6901 12.2521 4.1816 5.1604
SNU-1272 CTRP2 7.7989 12.7212 4.0306 5.6085
Caki-1 GDSC1; CTRP2 7.9242 11.8164 4.5339 3.5062
769-P GDSC1; CTRP2 7.9763 9.7494 5.4491 0.4695
CAL-54 GDSC1; CTRP2 8.5859 10.484 5.4231 0.296
ACHN GDSC1; CTRP2 8.8726 13.0883 4.5065 2.6344
KMRC-2 CTRP2 9.0775 14.8392 3.8438 4.7596
Caki-2 CTRP2 9.2367 17.7087 2.6099 9.0846
OS-RC-2 GDSC1; CTRP2 9.9482 19.3272 2.3062 9.2462
KMRC-1 GDSC1; CTRP2 10.7992 18.7419 3.0836 5.6239
VMRC-RCZ GDSC1; CTRP2 11.3699 20.2774 2.7231 6.2523
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW626 GDSC1 2.3432 11.8832 -1.7784 34.4218
SW620 GDSC1; CTRP2 3.2303 4.9749 3.1857 18.8988
SNU-C2B GDSC1 3.6758 5.7415 2.4183 6.315
LS123 GDSC1; CTRP2 3.6815 6.9156 3.1845 17.5349
GP5d GDSC1 3.6862 5.6092 2.4914 5.713
SK-CO-1 CTRP2 3.739 7.4028 3.0608 17.8405
T84 GDSC1; CTRP2 3.8242 6.4371 3.5038 15.9299
SW948 GDSC1 3.8818 6.7998 2.0503 8.5176
SW48 GDSC1; CTRP2 3.9465 5.4098 3.8918 14.1624
HCT 116 GDSC1; CTRP2 3.9505 7.0851 3.4097 15.9197
LS1034 GDSC1 4.0074 5.7038 2.6706 3.4526
LS513 GDSC1; CTRP2 4.0781 5.6363 3.9945 13.3864
COLO 320 CTRP2 4.3671 7.7792 3.5622 14.1971
DLD-1 CTRP2 4.5044 6.5416 4.2058 11.3341
NCI-H747 GDSC1; CTRP2 4.5589 8.5558 3.4069 14.3247
SW1463 GDSC1 4.5705 6.3146 2.7243 1.945
HCT 15 GDSC1 4.6638 9.4787 1.3043 11.6264
COLO201 CTRP2 4.6692 8.5317 3.5273 13.5675
KM12 GDSC1; CTRP2 4.6781 6.755 4.3132 10.4345
SNU-1040 GDSC1 4.7623 6.3908 2.7888 1.2949
CL-11 GDSC1; CTRP2 4.8066 6.4248 4.5734 9.0846
HT-55 GDSC1; CTRP2 4.8704 9.9614 3.0383 15.0614
SNU-81 GDSC1 4.9506 6.7105 2.7481 1.2818
COLO 320HSR GDSC1 4.9697 9.8913 1.3158 10.7207
HCC2998 GDSC1 4.9798 7.1908 2.5631 2.2837
RKO GDSC1; CTRP2 5.0936 8.7431 3.839 11.2824
SW837 GDSC1 5.2623 8.0007 2.3641 3.0498
SNU-175 GDSC1 5.266 7.3786 2.6259 1.5448
CaR-1 GDSC1 5.2994 7.4382 2.6174 1.5494
LS180 GDSC1; CTRP2 5.3985 8.0524 4.4618 8.0134
SW1116 GDSC1 5.6068 7.1384 2.8593 0.3384
SNU-C4 CTRP2 5.7114 6.5073 5.4989 3.0286
LS411N GDSC1; CTRP2 5.8742 9.3556 4.2449 7.8982
SNU-1033 CTRP2 5.9031 9.7712 4.062 8.6071
HCT 8 CTRP2 6.0469 8.7157 4.7108 5.6005
SNU-C5 GDSC1; CTRP2 6.377 10.0206 4.3262 6.6043
HT115 GDSC1; CTRP2 6.4603 8.0331 5.3717 2.1184
SNU-61 GDSC1; CTRP2 6.4788 8.7585 5.0302 3.4944
COLO205 GDSC1; CTRP2 6.5124 12.082 3.4062 10.1808
SNU-407 GDSC1; CTRP2 6.7011 11.5013 3.842 8.0538
HT-29 GDSC1; CTRP2 7.0604 9.6003 5.0251 2.6744
HCC-56 CTRP2 7.1387 8.0998 5.7236 0.2295
CW-2 GDSC1; CTRP2 7.1437 12.9202 3.4741 8.8203
SNU-C1 GDSC1; CTRP2 7.1588 11.9197 3.9758 6.7571
C2BBe1 GDSC1; CTRP2 7.395 15.072 2.6008 11.8534
NCI-H508 CTRP2 7.3983 10.9038 4.6291 3.7866
MDST8 GDSC1; CTRP2 7.9054 9.3773 5.5596 0.2691
LoVo GDSC1; CTRP2 7.9814 14.7666 3.173 8.7187
COLO 678 GDSC1; CTRP2 8.1096 14.3956 3.4392 7.4987
SW1417 GDSC1; CTRP2 8.1582 12.8323 4.2086 4.4594
CCK-81 GDSC1; CTRP2 8.2261 10.4929 5.2689 0.783
RCM-1 [Human ESC] GDSC1; CTRP2 8.4677 13.4874 4.0961 4.5175
SNU-C2A CTRP2 9.2945 11.4197 5.3573 0.2199
SNU-503 CTRP2 9.4936 17.6628 2.7965 8.0814
NCI-H716 GDSC1; CTRP2 9.5905 17.6758 2.8513 7.7648
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 3.695 5.5172 2.5433 5.2825
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Li-7 CTRP2 3.4089 9.5656 1.7919 23.4867
SNU-886 CTRP2 4.2343 5.8858 4.1099 12.4906
SNU-761 CTRP2 4.4291 6.6199 4.0966 11.961
SNU-182 CTRP2 4.5175 6.9425 4.069 11.817
SNU-878 CTRP2 4.5299 8.3013 3.4949 14.045
JHH-7 GDSC1 4.6402 7.1725 2.3822 4.0838
Huh-7 GDSC1 4.8698 6.748 2.6939 1.679
Hep-G2/C3A GDSC1 4.9442 6.3123 2.9007 0.585
HLE GDSC1 5.9185 8.569 2.45 1.7002
JHH-6 GDSC1; CTRP2 6.6869 10.2749 4.4378 5.6092
HLF CTRP2 7.3212 14.4331 2.8608 10.9702
SNU-475 GDSC1; CTRP2 7.4461 11.4677 4.3931 4.6545
HuH-1 GDSC1; CTRP2 7.6215 8.9324 5.61 0.2731
JHH-2 GDSC1; CTRP2 7.7413 13.3921 3.6705 7.1138
Hep 3B2.1-7 GDSC1; CTRP2 7.9859 14.1767 3.4604 7.5908
Hep-G2 CTRP2 8.0033 14.2153 3.4537 7.592
SK-HEP-1 GDSC1; CTRP2 8.0681 12.2365 4.4282 3.7364
SNU-449 GDSC1; CTRP2 8.1058 13.2821 3.9655 5.4575
JHH-4 GDSC1; CTRP2 8.1441 10.4544 5.2465 0.8917
SNU-423 GDSC1; CTRP2 8.1875 12.3547 4.4458 3.5357
JHH-1 GDSC1; CTRP2 8.1954 12.8255 4.2347 4.3159
PLC/PRF/5 CTRP2 8.2329 15.5023 2.9917 9.0505
SNU-387 GDSC1; CTRP2 8.4081 11.3271 5.0159 1.3802
SNU-398 GDSC1; CTRP2 8.7379 10.1964 5.5786 0.0758
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 204 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1581 GDSC1; CTRP2 2.3217 4.9227 2.1054 20.2404
LCLC-97TM1 GDSC1 2.582 5.2485 1.7069 16.0725
NCI-H1703 GDSC1 2.5855 28.8556 -10.0413 43.349
SBC-5 GDSC1; CTRP2 2.6811 3.4635 2.681 22.4071
NCI-H211 GDSC1; CTRP2 2.793 4.4987 2.7698 21.7392
DMS 454 CTRP2 2.8815 6.5568 2.4403 22.6288
NCI-H847 GDSC1 2.8929 4.5223 2.353 9.7655
SBC-3 GDSC1 2.9699 8.7431 0.3344 23.5052
NCI-H2106 CTRP2 3.2455 7.5374 2.1014 17.4857
ABC-1 GDSC1 3.3033 5.1802 2.3997 7.7361
NCI-H1155 GDSC1; CTRP2 3.3335 6.3179 2.723 14.6322
COR-L23 GDSC1 3.4402 6.5565 1.8254 11.7121
NCI-H1694 GDSC1; CTRP2 3.4847 5.9066 3.2873 17.7402
NCI-H1666 GDSC1; CTRP2 3.5239 6.0564 3.2904 17.609
NCI-H2087 GDSC1 3.6018 8.4237 1.0241 16.8888
NCI-H3122 GDSC1 3.6025 5.158 2.6514 4.7276
HCC827 GDSC1; CTRP2 3.7476 7.2234 3.14 17.5153
HCC44 GDSC1; CTRP2 3.7764 6.1728 3.5331 15.9651
COR-L311 GDSC1 3.8005 5.6013 2.5788 4.696
NCI-H358 GDSC1; CTRP2 3.8683 6.7539 3.0842 11.604
NCI-H1836 GDSC1 3.8907 5.4075 2.7344 3.2718
NCI-H1975 GDSC1 3.9304 6.4368 2.2643 6.7333
NCI-H889 CTRP2 4.0015 5.8054 3.8753 14.0464
EMC-BAC-1 GDSC1 4.0052 6.1757 2.4438 5.1549
NCI-H838 GDSC1 4.0124 7.3782 1.8624 9.5399
LC-2/ad GDSC1 4.0648 8.0007 1.5948 11.3539
LK-2 GDSC1 4.0688 6.5107 2.326 5.8719
NCI-H446 GDSC1; CTRP2 4.0898 6.0985 3.8963 13.7002
HCC15 GDSC1; CTRP2 4.0945 7.0321 3.1793 10.5938
IST-SL2 GDSC1 4.097 6.4208 2.3886 5.3246
PC-14 GDSC1; CTRP2 4.0973 6.7166 3.7042 14.3885
COR-L321 GDSC1 4.104 5.8406 2.6681 3.2401
DMS 53 GDSC1 4.1222 8.4246 1.4286 12.3661
Lu-139 GDSC1 4.1387 8.0024 1.6486 10.736
NCI-H1385 CTRP2 4.1391 6.2165 3.9157 13.4816
NCI-H1770 GDSC1 4.1596 6.3611 2.459 4.6383
NCI-H2228 GDSC1; CTRP2 4.1707 7.2669 3.5723 14.6854
HCC1588 CTRP2 4.2583 5.7312 4.1709 12.1996
NCI-H1437 GDSC1 4.2762 7.5334 1.9757 7.9271
NCI-H1734 GDSC1; CTRP2 4.2913 6.3769 3.1079 4.3012
IST-SL1 GDSC1 4.2978 6.2035 2.6197 3.1534
CAL-12T GDSC1; CTRP2 4.3475 8.8966 3.0392 16.3182
NCI-H1876 GDSC1 4.3784 9.1378 1.2667 12.7081
NCI-H661 GDSC1; CTRP2 4.3804 7.1973 3.8217 13.148
SW1271 GDSC1; CTRP2 4.3813 6.2107 4.1814 11.7853
NCI-H2171 GDSC1 4.4008 6.2295 2.6684 2.6086
NCI-H2141 GDSC1 4.4021 11.1164 0.3095 18.5665
NCI-H345 GDSC1 4.4026 6.3351 2.622 2.9201
UMC-11 GDSC1 4.4597 6.3904 2.6301 2.7524
NCI-H720 GDSC1 4.4901 6.0644 2.7895 1.6732
EPLC-272H GDSC1; CTRP2 4.5687 7.95 3.6929 13.1566
NCI-H810 GDSC1 4.5697 7.4966 2.1888 5.6111
RERF-LC-A1 CTRP2 4.6118 7.174 4.0743 11.5389
Calu-3 GDSC1; CTRP2 4.624 7.1315 4.1048 11.3873
NCI-H1688 GDSC1 4.6467 6.9455 2.4887 3.3412
Lu-99 CTRP2 4.6541 7.4268 3.5141 7.7431
NCI-H2135 GDSC1 4.6619 7.9452 2.0372 6.4784
NCI-H2081 GDSC1 4.6639 6.8046 2.5612 2.8256
NCI-H522 GDSC1 4.6918 7.9306 2.0631 6.2208
NCI-H23 GDSC1 4.7131 12.2684 -0.0259 19.4045
Ms-1 GDSC1 4.7158 8.2417 1.9323 7.0957
NCI-H1355 GDSC1 4.7286 7.8357 2.1306 5.6556
NCI-H1304 GDSC1 4.759 7.0803 2.4924 3.1029
RERF-LC-KJ GDSC1 4.7752 7.1279 2.4804 3.1518
Lu-165 GDSC1 4.8055 6.8886 2.6014 2.3249
NCI-H3255 GDSC1 4.8789 7.1521 2.5266 2.6706
PaCa-3 GDSC1 4.8798 7.1258 2.5385 2.5943
NCI-H1092 GDSC1 4.8835 7.1323 2.5377 2.5935
HCC33 GDSC1 4.8905 8.0101 2.1495 5.1643
NCI-H524 GDSC1 4.8964 7.2248 2.5045 2.7808
SHP-77 GDSC1; CTRP2 4.8976 8.1924 3.9109 11.457
CPC-N GDSC1 4.8991 7.033 2.5886 2.2548
Lu-99A GDSC1 4.9017 8.742 1.8165 7.4608
NCI-H187 GDSC1 4.9047 6.1043 2.9619 0.3888
NCI-H2227 GDSC1 4.9067 6.9803 2.6149 2.0852
NCI-H2291 GDSC1; CTRP2 4.9113 7.0414 3.2277 2.6436
DMS 114 GDSC1; CTRP2 4.923 6.943 4.4964 9.0554
NCI-H2405 GDSC1; CTRP2 4.9334 13.1724 1.5169 20.6835
NCI-H1184 CTRP2 4.9637 10.0489 3.083 14.6661
HCC1833 CTRP2 4.9657 7.1575 4.4492 9.1269
A-427 GDSC1 4.9668 9.2491 1.6196 8.6676
SW1573 GDSC1 4.9701 7.7705 2.3046 3.9479
NCI-H290 GDSC1 4.9705 9.5663 1.4715 9.6709
HCC2279 CTRP2 4.9844 8.3739 3.9105 11.2484
NCI-H69 GDSC1; CTRP2 4.9948 8.4285 3.8947 11.2875
NCI-H2803 GDSC1 4.9973 7.7915 2.3108 3.8554
NCI-H1650 GDSC1; CTRP2 4.9992 7.1979 4.466 8.9731
NCI-H1373 CTRP2 5.0077 8.0617 4.0804 10.5011
NCI-H64 GDSC1 5.0255 7.2861 2.5462 2.3156
HOP-92 GDSC1; CTRP2 5.0624 9.5413 3.4226 13.0606
NCI-H2722 GDSC1 5.0736 6.8141 2.763 1.0725
Calu-6 GDSC1; CTRP2 5.0942 11.9644 2.2595 17.6128
NCI-H2369 GDSC1 5.0995 8.1166 2.2239 4.2357
NCI-H1781 GDSC1 5.118 6.6112 2.8601 0.613
LC-1/sq GDSC1 5.1203 8.31 2.1491 4.6921
A-549 GDSC1; CTRP2 5.1605 8.3612 4.0865 10.1106
NCI-H2122 GDSC1; CTRP2 5.1792 7.2092 4.6443 7.8002
HCC366 CTRP2 5.1801 9.5108 3.5471 12.2836
NCI-H2347 GDSC1 5.1908 11.0667 0.902 12.7983
DMS 79 GDSC1 5.2168 11.1099 0.8989 12.7492
HOP-62 GDSC1; CTRP2 5.2188 6.9631 4.7944 7.1007
Lu-134-A GDSC1 5.2222 8.3896 2.1718 4.3448
HCC95 CTRP2 5.2327 8.3083 4.1809 9.5542
NCI-H510A GDSC1 5.2423 14.0508 -0.5123 20.2356
NCI-H460 GDSC1; CTRP2 5.2501 8.0288 4.3316 8.8948
NCI-H226 GDSC1; CTRP2 5.2624 7.5133 4.5876 7.8213
NCI-H1838 GDSC1; CTRP2 5.2683 8.7014 4.0243 10.117
LOU-NH91 GDSC1; CTRP2 5.2845 6.7503 4.9544 6.2966
NCI-H1436 GDSC1 5.3057 6.9654 2.8045 0.6891
NCI-H2461 GDSC1 5.308 8.9737 1.959 5.584
COR-L303 GDSC1 5.3101 6.4346 2.9958 0.1391
NCI-H1048 GDSC1 5.3287 13.095 0.0166 17.4403
EKVX GDSC1; CTRP2 5.33 7.9903 4.4267 8.317
NCI-H2009 GDSC1; CTRP2 5.344 12.7685 2.0822 17.7338
HCC1195 CTRP2 5.3464 6.7701 5.0098 5.9155
NCI-H513 GDSC1 5.3897 7.3743 2.6837 1.1297
NCI-H1648 GDSC1 5.3967 13.6099 -0.1857 18.2728
LXF 289 GDSC1; CTRP2 5.3989 9.9629 3.5242 11.895
NCI-H2869 GDSC1 5.4003 7.6931 2.5617 1.7199
NCI-H2595 GDSC1 5.4108 8.2852 2.32 3.0816
HCC2108 CTRP2 5.4254 9.8683 3.5949 11.5455
NCI-H596 GDSC1 5.4618 7.5364 2.6522 1.2049
NCI-H2444 GDSC1; CTRP2 5.4798 8.2908 4.4218 7.9941
NCI-H2804 GDSC1 5.5007 11.5532 0.8776 12.1536
NCI-H82 GDSC1 5.5194 6.8802 2.9175 0.2319
HCC2935 CTRP2 5.5205 7.8259 4.6866 6.8061
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 5.5596 7.833 4.0527 3.5067
NCI-H2373 GDSC1 5.5875 7.5753 2.6915 0.9211
NCI-H1563 GDSC1; CTRP2 5.6546 6.63 5.386 3.6247
MOR/CPR CTRP2 5.6744 8.4295 4.531 7.1131
HCC1438 CTRP2 5.7445 13.3103 2.1586 16.6038
ChaGo-K-1 GDSC1; CTRP2 5.749 9.8765 3.877 9.6922
NCI-H292 GDSC1; CTRP2 5.771 8.0815 4.7899 5.8254
SBC-1 GDSC1 5.7829 7.3277 2.8578 0.2742
NCI-H1993 GDSC1 5.8101 7.5897 2.7754 0.4777
NCI-H1792 GDSC1; CTRP2 5.8182 8.2952 4.7254 5.997
NCI-H322M GDSC1 5.8436 7.7535 2.7291 0.604
COLO 668 GDSC1 5.8937 7.5857 2.8082 0.3503
NCI-H2731 GDSC1 5.9251 13.3489 0.3045 14.3888
KNS-62 CTRP2 5.9453 7.218 5.3731 3.0189
Lu-135 GDSC1 5.948 7.5567 2.8381 0.2618
RERF-LC-Sq1 GDSC1 5.9565 8.3582 2.549 1.2098
NCI-H1693 GDSC1 5.9734 7.9919 2.6931 0.6463
RERF-LC-Ad1 CTRP2 5.9803 7.0247 4.6829 0.4432
EMC-BAC-2 GDSC1 5.9983 7.7538 2.7878 0.3592
NCI-H1568 GDSC1 6.0257 11.4012 1.2806 8.4667
NCI-H748 GDSC1 6.0289 7.8924 2.7503 0.4442
NCI-H2818 GDSC1 6.0489 8.0076 2.7168 0.5304
NCI-H727 GDSC1; CTRP2 6.0569 10.4375 3.8583 9.1579
NCI-H2591 GDSC1 6.0628 8.3531 2.5955 0.9361
NCI-H1793 GDSC1; CTRP2 6.0931 9.798 4.208 7.6239
NCI-H209 GDSC1 6.1809 8.2605 2.6765 0.5834
NCI-H196 GDSC1; CTRP2 6.2343 8.6863 4.8782 4.5476
COR-L88 GDSC1; CTRP2 6.26 8.9676 4.7583 5.0038
NCI-H841 GDSC1; CTRP2 6.3127 10.0242 4.2734 6.9408
NCI-H1573 GDSC1; CTRP2 6.3364 10.8701 3.8704 8.5816
NCI-H2795 GDSC1 6.3369 8.2583 2.7357 0.3558
Calu-1 CTRP2 6.351 8.9823 4.8225 4.5741
SK-LU-1 GDSC1; CTRP2 6.4453 13.453 2.6686 13.2659
HCC1171 CTRP2 6.6689 12.1208 3.5097 9.4779
NCI-H2029 GDSC1; CTRP2 6.8188 10.7605 4.2965 5.9791
NCI-H1944 GDSC1; CTRP2 6.8508 11.6456 3.8842 7.6271
RERF-LC-MS GDSC1; CTRP2 6.8722 10.4793 4.4733 5.1666
NCI-H2030 GDSC1; CTRP2 6.9037 11.0111 4.2357 6.0935
NCI-H1651 GDSC1; CTRP2 7.0047 13.1478 3.2578 9.9238
NCI-H322 CTRP2 7.0095 11.0448 4.2957 5.6816
NCI-H1299 GDSC1; CTRP2 7.3275 9.4977 5.2335 1.5871
BEN GDSC1; CTRP2 7.3452 8.2381 5.7545 0.1081
NCI-H526 GDSC1; CTRP2 7.3668 10.717 4.6968 3.5625
HCC78 GDSC1; CTRP2 7.3771 13.1638 3.525 8.243
HCC4006 CTRP2 7.3871 11.3857 4.3928 4.7366
NCI-H1915 GDSC1; CTRP2 7.4366 12.8717 3.7099 7.4076
NCI-H2286 CTRP2 7.6418 9.6858 5.3196 1.0235
NCI-H2126 CTRP2 7.654 8.8573 5.6505 0.1881
COR-L95 GDSC1; CTRP2 7.6795 12.4839 4.0642 5.639
NCI-H2110 GDSC1; CTRP2 7.7376 12.1227 4.274 4.7347
NCI-H441 GDSC1; CTRP2 7.8193 11.9625 4.4014 4.1362
DMS 273 GDSC1; CTRP2 7.8386 11.2264 4.7519 2.7917
NCI-H650 GDSC1; CTRP2 7.8723 18.7154 1.1603 16.1936
EBC-1 GDSC1; CTRP2 7.8896 14.0535 3.4538 7.7553
IA-LM GDSC1; CTRP2 7.9139 13.4903 3.7406 6.5923
SK-MES-1 GDSC1; CTRP2 8.0339 10.4978 5.1758 1.1706
NCI-H2085 GDSC1; CTRP2 8.0834 16.185 2.5566 10.922
NCI-H2172 GDSC1; CTRP2 8.1866 12.3866 4.4308 3.5923
NCI-H1435 GDSC1; CTRP2 8.2084 12.6322 4.3315 3.9368
NCI-H2023 GDSC1; CTRP2 8.2229 9.8625 5.5073 0.2613
NCI-H647 GDSC1; CTRP2 8.3062 15.1323 3.2191 8.0746
LCLC-103H GDSC1; CTRP2 8.314 14.7705 3.397 7.3796
NCI-H1395 CTRP2 8.3157 20.6145 0.5547 17.381
LC-1/sq-SF CTRP2 8.3507 12.8421 4.3209 3.8152
NCI-H2196 GDSC1; CTRP2 8.4174 18.6322 1.6018 13.8338
T3M-10 CTRP2 8.4201 16.597 2.5928 10.2828
Lu-65 GDSC1; CTRP2 8.4987 19.9742 1.0039 15.6872
NCI-H1755 GDSC1; CTRP2 8.5915 10.2981 5.4915 0.1912
COLO 699 CTRP2 8.6345 10.7789 5.3342 0.4422
NCI-H1339 CTRP2 8.6798 17.013 2.5706 9.9905
NCI-H1869 GDSC1; CTRP2 8.8952 14.0386 4.0989 4.0344
NCI-H2170 GDSC1; CTRP2 9.0871 14.4618 4.0195 4.1176
NCI-H1623 GDSC1; CTRP2 9.2794 19.1952 1.9305 11.4321
RERF-LC-Ad2 CTRP2 9.4045 15.4837 3.7437 4.7677
COR-L105 GDSC1; CTRP2 9.479 16.0636 3.5251 5.4685
NCI-H2342 GDSC1; CTRP2 9.7047 18.3012 2.6316 8.4081
NCI-H520 GDSC1; CTRP2 9.8765 17.7747 2.9817 6.9604
Hs 888.Lu CTRP2 8.3032 13.7891 3.8537 5.6357
⏷ Show the Full List of 204 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 4.0312 6.4874 2.3111 6.0884
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 5.4174 7.869 4.5684 7.5307
ONCO-DG-1 CTRP2 2.0819 7.9515 1.0824 29.7552
A2780 GDSC1; CTRP2 2.7721 3.9559 2.7696 21.8087
TOV-112D GDSC1 3.5615 4.9307 2.7327 4.2214
TOV-21G GDSC1 4.2213 15.2597 -1.8909 28.4265
Caov-4 GDSC1 4.2861 6.8153 2.3267 5.2981
IGROV-1 GDSC1; CTRP2 4.2923 6.1949 4.0892 12.389
OVK18 GDSC1; CTRP2 4.5678 7.4957 3.8921 12.37
SNU-119 CTRP2 4.5987 7.0795 4.0996 11.4763
ES-2 GDSC1 4.8376 9.6715 1.3315 10.9656
MCAS CTRP2 4.858 7.3824 4.2402 10.2355
SNU-840 CTRP2 5.0425 9.2309 3.5549 12.5652
OC 314 GDSC1; CTRP2 5.0968 8.0282 4.1835 9.866
SNU-8 CTRP2 5.1793 7.4964 4.5133 8.3265
COV434 CTRP2 5.2296 6.8866 4.8388 6.8969
OVCAR-3 GDSC1 5.2742 7.1912 2.7043 1.1476
OVCAR-5 GDSC1; CTRP2 5.2942 6.9886 4.86 6.6453
FU-OV-1 GDSC1; CTRP2 5.306 7.8129 4.4886 8.1197
TYK-nu GDSC1; CTRP2 5.4311 8.9897 4.0339 9.7128
OVCAR-8 GDSC1; CTRP2 5.5718 8.7271 4.2914 8.3342
OVCAR-4 GDSC1; CTRP2 5.6598 8.2962 4.5838 6.9243
OVTOKO GDSC1; CTRP2 5.8287 10.1357 3.8164 9.7831
Caov-3 GDSC1; CTRP2 5.9203 9.8141 4.0551 8.6016
OVKATE GDSC1 6.0727 7.9548 2.7446 0.4399
JHOC-5 CTRP2 6.6009 9.0665 4.9683 3.5556
Kuramochi GDSC1; CTRP2 6.8744 9.7019 4.8526 3.616
OVISE GDSC1; CTRP2 7.33 10.7813 4.6426 3.8237
OV56 GDSC1; CTRP2 7.4581 10.231 4.9789 2.3739
JHOM-1 CTRP2 7.9638 9.2673 5.6216 0.1525
HEY A8 CTRP2 7.9741 9.1833 5.6547 0.1084
COV362 CTRP2 7.9895 11.4836 4.7238 2.7327
OVSAHO CTRP2 8.0293 9.4096 5.5958 0.1739
SK-OV-3 GDSC1; CTRP2 8.165 12.9742 4.147 4.6855
JHOS-2 GDSC1; CTRP2 8.3108 13.7975 3.8546 5.6225
COV644 CTRP2 8.3154 14.0271 3.7498 6.019
RMG-I GDSC1; CTRP2 8.3155 14.42 3.5644 6.7324
EFO-21 GDSC1; CTRP2 8.3646 11.7235 4.8258 2.0185
EFO-27 GDSC1; CTRP2 8.4716 10.1085 5.5138 0.1873
OV7 CTRP2 8.4837 15.5002 3.1623 8.0464
OAW28 GDSC1; CTRP2 8.9097 10.7363 5.455 0.1737
OV-90 GDSC1; CTRP2 9.1078 15.9442 3.3549 6.5178
DOV13 GDSC1; CTRP2 11.0697 25.2535 0.2359 14.3605
OAW42 GDSC1; CTRP2 11.2199 21.8437 1.9279 9.0048
ES2 CTRP2 14.8397 34.1502 -1.5303 14.5532
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 5.6439 7.8731 4.778 6.1501
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 5.9832 8.68 4.6753 5.8739
Yamato-SS CTRP2 6.3205 9.5352 4.5234 5.8794
Rh41 GDSC1; CTRP2 2.7186 4.3015 2.7045 22.2044
A-204 GDSC1; CTRP2 3.4977 6.7792 3.0346 18.6258
G-401 GDSC1 3.5079 4.9259 2.6939 4.6986
Hs 633.T GDSC1 3.5712 5.4813 2.467 6.2702
SW684 GDSC1 4.3983 6.1239 2.714 2.3098
Rh30 GDSC1 4.4919 6.4305 2.6305 2.688
KYM-1 GDSC1; CTRP2 4.6028 6.8867 4.1816 11.1482
Rh18 CTRP2 4.6314 6.7569 4.2626 10.7584
EW-8 GDSC1 4.7901 7.1086 2.4972 3.0144
SW872 GDSC1 4.852 10.4325 0.9738 13.2677
VA-ES-BJ GDSC1 4.9384 7.2072 2.5345 2.5234
MFH-ino GDSC1 5.0149 8.3633 2.0627 5.4946
TE 441.T GDSC1; CTRP2 5.1834 10.4006 3.1129 14.0505
GCT GDSC1; CTRP2 5.3605 7.6858 4.6018 7.5269
TTC-709 CTRP2 5.6359 7.6297 4.89 5.7028
RD GDSC1; CTRP2 6.0158 13.8441 2.1207 16.1966
BT-16 CTRP2 6.2021 7.2334 5.5757 1.6861
HT-1080 GDSC1 6.4973 13.855 0.4365 12.3498
Tm87-16 CTRP2 6.5969 8.3904 5.2938 2.2347
SW982 GDSC1; CTRP2 6.9853 8.3093 5.5666 0.7647
MES-SA GDSC1; CTRP2 7.1054 9.8046 4.9579 2.8792
G-402 GDSC1; CTRP2 8.0277 15.0595 3.0636 9.0744
RKN GDSC1; CTRP2 8.0613 11.8371 4.6062 3.084
SK-LMS-1 GDSC1; CTRP2 8.3343 12.4732 4.4783 3.2576
Hs 729.T CTRP2 8.8047 15.5282 3.3582 6.8814
SK-UT-1 GDSC1; CTRP2 11.7767 24.0449 1.2543 10.4935
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.3246 11.2825 4.4001 4.7947
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; CTRP2 3.2333 5.549 3.0962 19.1995
NCI-H28 GDSC1; CTRP2 4.0293 5.9043 3.8819 13.9372
NCI-H2452 GDSC1; CTRP2 4.9328 7.8318 4.1131 10.5533
ACC-MESO-1 CTRP2 6.2555 12.2178 3.1318 11.775
NCI-H2052 GDSC1; CTRP2 7.6716 9.359 5.4673 0.5805
MPP 89 GDSC1; CTRP2 7.7728 13.0464 3.858 6.3257
IST-Mes1 GDSC1; CTRP2 7.949 10.4157 5.1678 1.2589
JL-1 CTRP2 8.3392 11.9571 4.7105 2.4313
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1 3.9537 6.7734 2.1163 7.7952
PC-3 GDSC1 5.9661 8.4235 2.528 1.2923
DU145 GDSC1; CTRP2 6.8277 11.414 3.9812 7.2659
VCaP GDSC1; CTRP2 7.6471 14.5609 3.0367 9.758
PaCa-3 CTRP2 8.0387 9.3107 5.634 0.1211
22Rv1 GDSC1; CTRP2 8.2358 10.5947 5.2327 0.8734
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 4.997 7.0109 3.2963 2.2142
A-253 GDSC1; CTRP2 7.2837 10.589 4.7033 3.6455
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 3.2091 4.1335 2.839 4.6443
Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GSS CTRP2 2.6682 4.9441 2.5916 22.7526
ECC10 GDSC1; CTRP2 2.8142 4.0768 2.8101 21.5335
RF-48 GDSC1 3.2654 5.0838 2.4156 7.7518
HGC-27 GDSC1; CTRP2 3.8357 5.5181 3.7546 14.9918
NUGC-4 GDSC1; CTRP2 4.1363 5.8256 4.0174 13.1232
23132/87 GDSC1; CTRP2 4.281 5.3509 4.2557 11.8334
HSC-39 GDSC1 4.3054 5.9131 2.7552 2.2097
GSU CTRP2 4.3855 5.8239 4.2891 11.3847
SNU-620 CTRP2 4.5228 8.3506 3.4652 14.1815
IM95 GDSC1; CTRP2 4.6909 23.6895 -3.93 33.8193
ECC12 CTRP2 4.6968 11.2552 2.2455 18.5713
RERF-GC-1B GDSC1 4.7427 7.7719 2.169 5.353
SCH GDSC1 4.7931 6.8089 2.6291 2.1744
TGBC11TKB GDSC1 4.8981 8.6206 1.8712 7.0869
MKN1 GDSC1; CTRP2 5.0319 7.2393 4.4812 8.828
GCIY GDSC1 5.0587 8.2927 2.121 5.0057
SNU-16 GDSC1 5.0698 6.7664 2.7801 0.9959
SNU-216 CTRP2 5.127 8.8328 3.8275 11.252
TMK-1 GDSC1 5.1283 7.6844 2.4294 2.8642
AGS GDSC1; CTRP2 5.1726 8.6015 3.9825 10.5094
OCUM-1 GDSC1 5.1783 7.7702 2.4189 2.8482
KE-39 CTRP2 5.3432 10.4052 3.2552 13.1205
SNU-601 CTRP2 5.433 16.4237 0.3369 23.3748
MKN74 CTRP2 5.4516 8.3116 4.3855 8.2083
MKN28 GDSC1 5.5992 7.9291 2.5591 1.5083
SNU-1 GDSC1; CTRP2 5.9081 10.7543 3.5749 10.6288
Fu97 GDSC1; CTRP2 6.6204 13.1125 2.9781 11.7187
SNU-719 CTRP2 6.8562 10.8137 4.2978 5.9135
NCI-N87 GDSC1; CTRP2 6.9953 10.9172 4.3478 5.4906
Hs 746.T GDSC1; CTRP2 7.0187 9.0718 5.245 1.8799
SNU-5 GDSC1; CTRP2 7.0258 12.3113 3.6865 8.1497
SNU-668 CTRP2 7.0275 10.7028 3.6471 3.1827
SH-10-TC CTRP2 7.7084 11.2261 4.674 3.2297
NUGC-3 GDSC1; CTRP2 8.0573 11.6916 4.6695 2.8579
KATO III CTRP2 8.398 10.6141 5.2976 0.6218
MKN7 GDSC1; CTRP2 8.5484 14.193 3.8197 5.4603
HuG1-N CTRP2 8.887 18.1383 2.1711 11.1419
LMSU CTRP2 10.4008 19.3107 2.5943 7.7107
MKN45 GDSC1; CTRP2 10.5007 21.2036 1.7787 10.3415
SNU-1077 CTRP2 4.2113 8.0185 3.2977 15.6465
SNG-M GDSC1; CTRP2 5.2589 8.0821 4.3146 8.9439
SNU-685 CTRP2 7.568 12.7542 3.8588 6.6151
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CGTH-W-1 GDSC1; CTRP2 2.8064 11.731 0.1969 30.1855
8305C GDSC1; CTRP2 3.6747 5.4309 3.5963 16.0548
B-CPAP GDSC1; CTRP2 3.8234 6.5052 3.4807 16.018
HTC-C3 GDSC1 3.9264 6.2763 2.3398 6.167
8505C GDSC1; CTRP2 4.1065 6.7755 3.6928 14.4051
IHH-4 GDSC1 4.1229 7.0987 2.079 7.5854
CAL-62 GDSC1 4.3084 6.5405 2.4703 4.1946
TT GDSC1; CTRP2 4.6959 6.4504 4.4448 9.8858
ASH-3 GDSC1 4.7121 6.6376 2.6601 2.1134
WRO GDSC1 5.2102 6.9502 2.77 0.9092
ML-1 [Human leukemia] GDSC1; CTRP2 5.2659 7.1676 4.7506 7.1547
K5 GDSC1 5.3153 6.9125 2.8282 0.5937
TT2609-C02 GDSC1; CTRP2 5.3293 12.2574 2.3235 16.853
KMH-2 GDSC1 5.843 7.8718 2.6854 0.7555
BHT-101 GDSC1; CTRP2 6.9726 8.5149 4.5357 0.3113
FTC-133 GDSC1; CTRP2 7.7667 11.5689 4.5515 3.6254
SW579 CTRP2 8.2856 13.0152 4.2025 4.3311
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-4 GDSC1; CTRP2 4.0363 8.2239 3.028 17.1621
BHY GDSC1; CTRP2 4.1281 5.902 3.9901 13.2459
PCI-04B GDSC1 4.1357 6.1359 2.5499 4.0271
SNU-899 CTRP2 4.1554 8.0494 2.1628 9.1451
BB30-HNC GDSC1 4.2092 6.8722 2.2482 6.0785
SCC-15 GDSC1 4.3199 6.7362 2.3859 4.7805
SAS GDSC1 4.3272 8.2765 1.6508 10.1616
YD-8 CTRP2 4.4956 6.8417 4.085 11.8168
SNU-1076 CTRP2 4.5307 6.2868 4.3205 10.8306
YD-10B CTRP2 4.573 7.2802 2.8755 4.8646
CAL-27 GDSC1 4.6913 7.4017 2.3081 4.4909
SCC-25 GDSC1; CTRP2 4.7438 6.9635 4.2997 10.3054
OSC-20 GDSC1 4.7758 7.1605 2.4662 3.2443
KON GDSC1 4.8342 6.8273 2.6426 2.0294
Ca9-22 GDSC1 4.8374 7.2662 2.4539 3.2112
OSC-19 GDSC1 4.875 7.5267 2.3594 3.7661
PCI-15A GDSC1 4.9962 6.6737 2.7837 1.0531
BICR 10 GDSC1 5.0328 7.8992 2.2829 3.9724
LB771-HNC GDSC1 5.0685 7.441 2.5024 2.5128
SNU-1214 CTRP2 5.0752 9.8801 2.6522 10.6842
JHU-011 GDSC1 5.1494 7.7556 2.4099 2.9508
HO-1-N-1 GDSC1 5.187 7.1241 2.6915 1.3012
PCI-30 GDSC1 5.2017 7.4766 2.5549 2.011
PCI-38 GDSC1 5.2487 7.688 2.49 2.3164
CAL-33 GDSC1; CTRP2 5.3314 7.0574 4.8666 6.5242
NCI-H3118 GDSC1 5.4958 7.6345 2.6289 1.2803
BB49-HNC GDSC1 5.6053 8.2667 2.4255 2.1938
SNU-46 CTRP2 5.7517 8.4849 3.872 3.9842
PE/CA-PJ15 GDSC1 5.7679 8.3042 2.4867 1.6818
PCI-06A GDSC1 5.8364 7.8572 2.6882 0.7499
BICR 16 CTRP2 5.8609 7.8057 5.0065 4.7302
HO-1-u-1 GDSC1 5.8648 7.8504 2.702 0.6825
BICR 22 GDSC1 5.91 7.1633 2.9575 0.0806
KOSC-2 GDSC1 5.9251 7.6673 2.7911 0.3809
BICR 78 GDSC1 5.9984 8.2089 2.6231 0.878
SKN-3 GDSC1 6.1057 8.3604 2.6103 0.8507
DOK GDSC1 6.3298 8.3823 2.6895 0.4742
JHU-022 GDSC1 6.4027 8.4387 2.6967 0.4246
HSC-2 GDSC1; CTRP2 6.8206 10.7569 4.2996 5.9632
HSC-4 GDSC1; CTRP2 7.1317 9.5451 5.0959 2.3123
SAT [Human HNSCC] GDSC1 7.4084 9.7366 2.6102 0.2859
BICR 6 CTRP2 7.8271 12.1237 4.3309 4.3983
PE/CA-PJ41 (clone D2) CTRP2 8.2058 13.3226 4.0102 5.1582
SCC-9 GDSC1; CTRP2 8.3001 16.0679 2.7652 9.8129
BICR 18 CTRP2 8.3268 11.8195 4.7639 2.2601
HSC-3 GDSC1; CTRP2 8.3699 15.2597 3.201 8.0553
SNU-1041 CTRP2 8.3825 11.0567 5.1148 1.1082
FaDu GDSC1; CTRP2 8.6955 15.9194 3.103 7.9838
BICR 56 CTRP2 8.9202 19.3114 1.6278 12.9842
Detroit 562 GDSC1; CTRP2 9.1584 16.7709 3.0011 7.7591
BICR 31 GDSC1; CTRP2 10.0812 18.1136 2.9499 6.8396
SNU-1066 CTRP2 14.898 41.5255 -4.9705 21.1926
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J CTRP2 2.212 3.1852 2.2119 25.5323
BFTC-905 GDSC1 3.2812 4.4948 2.7232 5.2704
UM-UC-3 GDSC1 3.7982 7.013 1.8818 10.0653
VM-CUB-1 CTRP2 4.6978 8.9627 3.353 14.2005
5637 GDSC1; CTRP2 4.9678 7.8424 4.1431 10.3453
SW780 GDSC1 5.0009 8.2681 2.0978 5.2844
647V GDSC1 5.1035 10.474 1.1271 11.6072
TCCSUP GDSC1; CTRP2 5.1411 8.1365 4.1752 9.7936
SW1710 GDSC1; CTRP2 5.4185 7.4173 4.7856 6.6375
RT-112 GDSC1; CTRP2 5.4458 7.699 4.6774 7.0162
RT-4 GDSC1 5.5527 7.1183 2.8461 0.3992
U-BLC1 CTRP2 5.6252 13.0008 2.211 16.6532
CAL-29 GDSC1 5.6799 7.5022 2.7565 0.6108
KMBC-2 CTRP2 6.151 9.553 4.3781 6.8004
T24 GDSC1; CTRP2 7.2724 12.0694 3.9839 6.5502
HT-1197 GDSC1; CTRP2 7.7991 15.0833 2.8907 10.0885
UM-UC-1 CTRP2 7.9143 14.3304 3.3372 8.1765
KU-19-19 GDSC1; CTRP2 8.4619 19.0179 1.4454 14.2954
HT-1376 GDSC1; CTRP2 8.5194 13.8494 3.961 4.9629
639V GDSC1; CTRP2 10.6453 22.4386 1.2913 11.734
J82 GDSC1; CTRP2 12.1847 23.9685 1.5351 9.1864
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BPH-1 GDSC1 0.6297 3.4795 0.3462 35.6735
PA-1 GDSC1 2.3039 3.5966 2.1342 14.2896
OVMIU GDSC1 3.4057 5.1086 2.5209 6.41
SW954 GDSC1 3.8158 5.1985 2.7841 3.093
Ca Ski GDSC1 4.2616 9.8541 0.8274 15.9471
NEC8 GDSC1 4.3249 6.7833 2.367 4.9066
JEG-3 GDSC1 4.336 7.2131 2.1705 6.3238
SW756 GDSC1 4.412 8.73 1.4903 11.06
SKN GDSC1 4.4506 7.2023 2.2507 5.4486
C-33 A GDSC1 4.5641 7.8778 2.0054 6.9485
C-4-I GDSC1 4.6475 7.0554 2.4397 3.6728
SiHa GDSC1 4.6543 6.9234 2.503 3.2302
NCC-IT GDSC1 4.7309 6.5317 2.7149 1.7547
HEC-1 GDSC1 4.8073 6.7674 2.6542 2.0009
DoTc2 4510 GDSC1 4.8364 8.3241 1.9707 6.5343
OV17R GDSC1 4.8451 8.012 2.121 5.4606
OVCA433 GDSC1 4.871 7.0763 2.5552 2.5049
KGN GDSC1 4.8742 7.3267 2.4477 3.1844
JAR GDSC1 4.8853 6.3674 2.8545 0.8314
ACC-OV7 GDSC1 4.9492 7.824 2.2687 4.2292
OVCA420 GDSC1 5.0323 7.051 2.648 1.7173
SKG-IIIa GDSC1 5.0426 9.6687 1.4705 9.4951
OMC-1 [Human cervical carcinoma] GDSC1 5.113 7.6844 2.4213 2.9398
SiSo GDSC1 5.131 7.4808 2.5177 2.3265
DSH1 GDSC1 5.1335 7.3112 2.5899 1.9066
ME-180 GDSC1 5.1667 9.5353 1.6136 8.2246
MS751 GDSC1 5.2328 7.6025 2.5179 2.1786
HEY GDSC1 5.2364 7.8277 2.4246 2.7218
HT-3 GDSC1 5.2743 7.1107 2.7358 1.0027
LB831-BLC GDSC1 5.3146 7.3638 2.6543 1.3466
SW962 GDSC1 5.488 7.5395 2.6626 1.1327
NT2-D1 GDSC1 5.5624 7.4971 2.7106 0.8636
UWB1.289 GDSC1 5.5682 9.046 2.0746 4.3394
PEO1 GDSC1 5.792 8.1068 2.575 1.2432
CAL-39 GDSC1 5.8735 14.0015 -0.0428 16.3266
JHOS-3 GDSC1 6.0664 7.885 2.7669 0.3842
HeLa GDSC1; CTRP2 7.3124 8.0752 5.7993 0.0592
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance. Biochem Pharmacol. 2012 Sep 15;84(6):766-74.