Details of the Drug

General Information of Drug (ID: DMF3IBC)

Drug Name
Plasma derived human butyrylcholinesterase
Synonyms
Plasma derived human butyrylcholinesterase (im, drug induced neurotoxicity); HuBChE (im, drug induced neurotoxicity), Dynport; Bioscavenger (im, drug induced neurotoxicity), Dynport/Baxter; Plasma derived human butyrylcholinesterase (im, drug induced neurotoxicity), Dynport/Baxter
Indication
Disease Entry ICD 11 Status REF
Neurotoxicity NE61 Phase 1 [1]
Cross-matching ID
TTD ID
D04JMI

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cholinesterase (BCHE) TTEB0GD CHLE_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00333528) A Study of Plasma-Derived Human Butyrylcholinesterase Administered Intramuscularly. U.S. National Institutes of Health.
2 Acetylcholinesterase-Fc Fusion Protein (AChE-Fc): A Novel Potential Organophosphate Bioscavenger with Extended Plasma Half-Life. Bioconjug Chem. 2015 Aug 19;26(8):1753-8.