Details of the Drug

General Information of Drug (ID: DMFEGB0)

Drug Name

Segesterone acetate; ethinyl estradiol

Indication

Disease Entry	ICD 11	Status	REF
Contraception	QA21	Approved	[1]
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ATC Code

G03CA01: Segesterone acetate; ethinyl estradiol

G03CA: Natural and semisynthetic estrogens, plain

G03C: ESTROGENS

G03: SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM

G: GENITO URINARY SYSTEM AND SEX HORMONES

L02AA03: Segesterone acetate; ethinyl estradiol

L02AA: Estrogens

L02A: HORMONES AND RELATED AGENTS

L02: ENDOCRINE THERAPY

L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
G-protein coupled estrogen receptor 1 (GPER1)	TTDSB34	GPER1_HUMAN	Modulator	[1]
Progesterone receptor (PGR)	TTUV8G9	PRGR_HUMAN	Modulator	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Contraception

ICD Disease Classification

QA21

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Progesterone receptor (PGR)	DTT	PGR	3.26E-38	-3.79	-2.5

Molecular Expression Atlas (MEA)

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References

1	2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.