Details of the Drug

General Information of Drug (ID: DMFSJ9O)

Drug Name
BRD4770
Synonyms BRD 4770; BRD-4770
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
Chemical Identifiers
Formula
C25H23N3O3
Canonical SMILES
COC(=O)C1=CC2=C(C=C1)N(C(=N2)NC(=O)C3=CC=CC=C3)CCCC4=CC=CC=C4
InChI
1S/C25H23N3O3/c1-31-24(30)20-14-15-22-21(17-20)26-25(27-23(29)19-12-6-3-7-13-19)28(22)16-8-11-18-9-4-2-5-10-18/h2-7,9-10,12-15,17H,8,11,16H2,1H3,(H,26,27,29)
InChIKey
UCGWYCMPZXDHNR-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
72193870
ChEBI ID
CHEBI:131143
TTD ID
D0LA0P

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 5.0804 7.0764 3.3171 1.8684
HuH-28 CTRP2 5.6228 7.3753 3.4784 0.773
SNU-308 CTRP2 5.8834 7.6401 3.4921 0.5721
SNU-1079 CTRP2 6.3835 8.6465 4.1989 1.6534
SNU-1196 CTRP2 7.2686 8.9839 4.481 0.2928
HuCC-T1 CTRP2 7.4229 8.9849 4.5392 0.164
SNU-245 CTRP2 8.023 10.0868 4.3738 0.2572
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U2OS CTRP2; CTRP1 3.6492 6.7018 2.8917 12.2423
MHH-ES-1 CTRP2 6.3104 8.0664 3.5092 0.3417
SW1353 CTRP2 7.2701 8.7173 4.5768 0.147
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MCF-7 CTRP2; CTRP1 3.7433 6.7721 2.9562 11.7441
HCC1954 CTRP2 4.8238 7.2579 3.066 3.2716
HCC1937 CTRP2 5.2812 9.0425 2.5204 4.9202
HMC-1-8 CTRP2 5.5062 6.8705 3.6262 0.4284
KPL-1 CTRP2 5.6045 7.8387 4.0821 3.0835
CAMA-1 CTRP2 5.7392 23.5172 -4.2876 26.6072
HCC1806 CTRP2 5.9221 7.6741 3.4958 0.5416
CAL-51 CTRP2 6.0485 7.8144 3.4961 0.4779
CAL-148 CTRP2 6.1672 8.014 3.4702 0.4837
CAL-120 CTRP2 6.6505 8.0249 4.5873 0.3081
HCC1395 CTRP2 7.01 8.7589 3.5257 0.1422
JIMT-1 CTRP2 7.1172 8.6197 4.5541 0.2147
HDQ-P1 CTRP2 7.2692 8.7227 4.5745 0.15
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.0188 7.0853 3.7465 0.064
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GB-1 CTRP2 4.4389 6.001 3.4054 2.4094
LN-229 CTRP2; CTRP1 5.3345 9.2626 3.1821 7.3634
GaMG CTRP1 5.3575 9.7702 2.9472 17.0844
SF295 CTRP2 5.3741 10.8185 1.7246 8.1956
SF126 CTRP2 5.5449 7.2644 3.4865 0.8039
Daoy CTRP2 5.6724 8.0429 3.2221 1.5901
SNU-1105 CTRP2 5.7277 7.1868 3.5997 0.3837
U-87MG ATCC CTRP2 5.7627 7.8643 3.3449 1.089
CAS-1 CTRP2 5.8057 8.17 4.0615 2.8727
SNU-466 CTRP2 5.8173 6.8724 3.7481 0.0919
LN-18 CTRP2 5.857 6.6981 3.8203 0.0266
SNU-201 CTRP2 6.5572 8.0147 4.5516 0.4301
NMC-G1 CTRP2 6.6958 8.1722 4.5505 0.3678
SNU-738 CTRP2 6.8393 9.9575 3.8733 2.3508
ONS-76 CTRP2 7.545 9.3232 4.4652 0.24
SNU-489 CTRP2 7.8077 18.8661 0.2792 14.317
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP1 1.0972 3.9214 0.9844 55.7682
JHUEM-2 CTRP2; CTRP1 1.7291 3.6528 1.6909 22.2904
KLE CTRP2; CTRP1 4.9086 7.2895 3.816 5.5162
HEC-108 CTRP2; CTRP1 5.2068 6.5158 4.4497 2.2869
HEC-59 CTRP2; CTRP1 5.2945 8.4378 3.5615 5.8477
HEC-265 CTRP2 5.438 6.633 3.6882 0.3103
HEC-6 CTRP2 5.9306 7.1923 3.678 0.1617
HEC-251 CTRP2 6.1817 7.4534 3.6786 0.109
HEC-1-B CTRP2 6.5982 8.2193 3.5639 0.1718
RL95-2 CTRP2 7.0927 8.5128 4.583 0.1772
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 4.8021 6.426 4.151 4.3384
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SU-DHL-5 CTRP1 0.3032 0.8564 0.3032 67.938
THP-1 CTRP1 0.6347 1.8481 0.6344 63.1311
PL21 CTRP1 0.6775 2.511 0.6688 62.1479
NU-DUL-1 CTRP1 0.7643 3.5132 0.6859 59.9738
OCI-AML-3 CTRP1 0.7836 2.7312 0.7694 60.6051
SKM-1 CTRP1 1.2421 3.3692 1.2053 54.2843
BL-70 CTRP1 1.2669 4.4306 1.0736 53.4902
GDM-1 CTRP1 1.468 3.553 1.4258 51.2348
KE-37 CTRP2 1.6523 2.91 1.6492 22.6088
NOMO-1 CTRP1 1.918 3.1075 1.9148 44.8864
U-937 CTRP1 2.3128 6.3045 1.649 42.0188
RPMI-8226 CTRP1 2.5125 5.0603 2.2796 37.7723
NALM-6 CTRP2 2.686 7.5899 1.065 16.7101
KMS-11 CTRP1 2.8662 7.4286 1.7696 37.3855
PF-382 CTRP2 2.9333 5.3712 2.3402 10.6017
P12-Ichikawa CTRP2 2.9611 5.3734 2.6732 14.9009
LP-1 CTRP1 3.1265 7.7834 1.8764 35.1809
JVM-3 CTRP2 3.3123 6.4848 2.1943 10.2443
HDLM-2 CTRP2 3.3556 7.4382 1.7689 12.013
MOLM-16 CTRP1 3.4774 4.9886 3.3516 23.5286
CML-T1 CTRP2 3.5265 6.609 2.8004 12.84
MV4-11 CTRP2 3.6077 6.3428 2.5387 8.0098
JVM-2 CTRP2 3.6497 7.1785 1.4641 6.4685
SU-DHL-4 CTRP1 3.7487 6.0547 3.2727 22.4328
KMS-21-BM CTRP2 3.8706 7.6808 2.6545 12.5632
MOLM-13 CTRP2 3.8761 8.6317 2.2035 14.3814
EJM CTRP1 4.168 6.9346 3.3042 19.7949
DoHH2 CTRP2 4.4389 13.5668 -0.3626 18.3582
KMS-27 CTRP2 4.4912 7.4044 2.7523 5.2117
Ku812 CTRP2 4.5812 8.1027 2.475 6.2816
HEL CTRP2 4.6724 6.3841 2.4659 0.7053
AMO1 CTRP1 4.9249 5.9212 4.5115 5.5172
NCO2 CTRP2 4.9398 12.9089 1.0247 16.7059
DEL CTRP2 4.9711 6.7877 4.1109 4.0676
JURL-MK1 CTRP2 4.9792 11.754 1.6351 14.2959
NCI-H929 CTRP2 4.9878 8.4248 2.6156 4.9661
KMS-26 CTRP2 5.2127 7.6984 3.1114 2.5333
KCL-22 CTRP2 5.3053 7.4932 3.2605 1.8282
Jurkat CTRP2 5.3823 9.3789 1.5557 3.4228
OCI-Ly10 CTRP1 5.502 7.4282 4.2201 5.9087
LAMA-84 CTRP2 5.6205 11.4579 0.749 6.5218
KM-H2 CTRP2 5.6805 10.9649 1.0132 5.3155
KHM-1B CTRP2 5.9011 10.632 2.1751 5.4779
SU-DHL-1 CTRP2 5.9973 8.708 3.9329 3.1213
EM-2 CTRP2 5.9987 13.1786 1.7427 11.9782
P31/FUJ CTRP2 6.0847 11.142 2.8132 7.5372
Peer CTRP2 6.3391 8.3129 4.3213 1.2709
RPMI-8402 CTRP2 6.3837 10.1956 3.4812 4.3898
Ki-JK CTRP2 6.5524 9.2953 4.0053 2.1741
WSU-DLCL2 CTRP2; CTRP1 6.6565 8.3736 4.4682 0.6332
HT CTRP2 6.7653 11.6824 3.0268 5.669
KMM-1 CTRP2 8.0195 10.321 4.2882 0.3961
EHEB CTRP2 8.0575 18.7396 -0.2529 11.8219
KE-97 CTRP2 9.0521 19.4866 0.0268 9.5693
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RCC10RGB CTRP1 4.5058 6.6664 3.7579 14.2159
769-P CTRP2 5.968 7.2888 3.6578 0.1833
TUHR4TKB CTRP2 6.0759 7.9031 4.3556 1.4077
SNU-1272 CTRP2 6.3319 9.4781 2.9529 1.9301
OS-RC-2 CTRP2 6.8004 8.7229 4.381 0.7351
BFTC-909 CTRP2 7.1588 8.5291 4.6017 0.1377
KMRC-20 CTRP2 7.5003 8.9667 4.5734 0.1107
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CW-2 CTRP1 1.2332 2.8281 1.2258 54.5756
SW948 CTRP1 1.295 4.8754 0.9999 52.9788
COLO 320 CTRP1 1.3859 8.0799 -0.4581 47.5163
HT-55 CTRP1 1.4849 3.5837 1.4406 51.0047
SW620 CTRP1 1.5872 3.1198 1.5776 49.6012
SNU-C5 CTRP1 1.878 3.9392 1.8168 45.6591
SW480 CTRP1 2.0701 4.2508 1.9769 43.132
KM12 CTRP1 2.3787 5.6931 1.939 40.4613
SNU-81 CTRP1 2.4906 4.7354 2.3373 37.6367
RCM-1 [Human ESC] CTRP1 2.6421 6.618 1.8773 38.5856
SNU-175 CTRP1 2.8437 4.7258 2.7235 32.4882
COLO 678 CTRP1 2.8979 7.2601 1.8757 36.7263
SNU-C4 CTRP1 3.1371 5.7288 2.7468 30.2456
SNU-61 CTRP1 3.3356 5.8638 2.9102 27.7697
CL-34 CTRP1 3.4505 6.4293 2.8043 27.7784
CL-40 CTRP1 3.8567 5.8559 3.4676 20.2256
SNU-1040 CTRP1 4.2851 7.2565 3.2634 19.506
LS180 CTRP2; CTRP1 4.7365 7.7939 3.4142 7.5543
HT115 CTRP2; CTRP1 4.7921 6.5625 4.0746 4.678
SNU-C2A CTRP2 4.9556 7.5118 3.0336 3.2127
HCT 116 CTRP2; CTRP1 5.0147 5.6708 4.7154 1.5297
LS123 CTRP1 5.0751 10.4579 2.3729 22.2011
HCT 8 CTRP1 5.1319 9.6561 2.8208 18.9394
MDST8 CTRP1 5.2495 7.9181 3.7849 10.6719
HT-29 CTRP2; CTRP1 5.5655 6.9151 4.5115 1.4857
LoVo CTRP1 5.6716 10.5982 2.7818 17.0673
DLD-1 CTRP2 5.8711 7.0222 4.6298 0.6548
RKO CTRP1 6.0936 8.0791 4.2991 3.5642
NCI-H508 CTRP1 6.1971 12.1505 2.4112 17.6732
COLO205 CTRP2 6.428 8.8138 4.1496 1.7839
SK-CO-1 CTRP2 6.5546 9.531 3.8997 2.5599
SW48 CTRP2 6.7444 9.2275 4.142 1.5107
OUMS-23 CTRP2 6.7614 7.7631 4.7231 0.0695
LS411N CTRP2 6.9584 8.2776 4.616 0.1617
LS513 CTRP2 7.1641 8.5706 4.5891 0.1528
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 CTRP1 2.6617 7.0435 1.7229 39.0322
SNU-449 CTRP1 4.0577 8.1768 2.6032 25.5871
SNU-182 CTRP2 5.5198 12.0278 1.2385 10.0103
Hep-G2 CTRP1 6.0439 9.5074 3.5924 9.5127
Hep 3B2.1-7 CTRP2 6.0791 7.522 3.6167 0.2199
JHH-6 CTRP1 6.1812 6.923 4.8188 0.1705
SNU-878 CTRP2 6.9452 8.9725 4.3478 0.7374
Li-7 CTRP2 7.1772 9.0645 4.4139 0.4588
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 80 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1963 CTRP1 -0.8471 1.465 -0.8547 79.8749
NCI-H1105 CTRP1 -0.1126 5.118 -0.6011 64.5863
COR-L51 CTRP1 0.3423 7.4275 -0.8852 58.5274
NCI-H596 CTRP1 1.4732 3.5191 1.4344 51.1687
NCI-H1876 CTRP1 1.6209 3.7321 1.5686 49.1599
NCI-H1694 CTRP1 1.8722 7.0814 0.8772 47.1914
NCI-H2122 CTRP1 1.8809 3.5217 1.86 45.4868
NCI-H1930 CTRP1 1.882 7.3125 0.7939 47.1875
NCI-H2141 CTRP1 2.4226 4.8268 2.2417 38.72
NCI-H3255 CTRP1 2.5311 6.5908 1.7707 39.8502
SCLC-21H CTRP1 2.6366 4.581 2.5288 35.3259
COLO 668 CTRP1 2.6879 6.3047 2.0497 37.495
NCI-H2286 CTRP1 3.1909 6.1682 2.638 30.5998
NCI-H211 CTRP2 3.1986 6.7156 1.9749 11.4882
NCI-H1435 CTRP1 3.3745 7.9819 2.0333 32.8622
NCI-H2081 CTRP1 3.4023 5.4824 3.1199 25.7853
SK-LU-1 CTRP1 3.655 6.9718 2.7769 26.7041
NCI-H1781 CTRP1 3.7101 6.3388 3.1126 23.9127
NCI-H1155 CTRP2 3.8058 8.7554 2.0772 15.055
NCI-H2009 CTRP2; CTRP1 3.8182 8.5076 2.2162 14.5447
HCC4006 CTRP1 4.0033 6.3466 3.4106 19.837
LXF 289 CTRP1 4.0359 6.414 3.4135 19.6271
NCI-H69 CTRP2 4.2166 9.358 1.559 11.0495
HCC44 CTRP2 4.2434 6.3413 3.0877 4.1774
Lu-99 CTRP2 4.2439 7.3828 3.1557 9.632
NCI-H1836 CTRP1 4.3223 8.5522 2.6659 23.7819
COLO 699 CTRP2; CTRP1 4.4421 10.0876 2.0136 13.9665
NCI-H2342 CTRP1 4.494 9.3733 2.4145 24.5775
NCI-H2172 CTRP1 4.5191 6.0603 4.0591 11.5249
Calu-3 CTRP2 4.5298 7.3137 2.8265 4.8122
NCI-H841 CTRP1 4.6113 7.4726 3.4614 16.244
NCI-H526 CTRP2 4.6602 6.3567 3.3874 2.14
NCI-H441 CTRP1 4.7019 9.6059 2.4814 23.1675
SBC-5 CTRP2 4.7723 7.7604 2.7858 4.5743
NCI-H2073 CTRP1 4.8419 8.1322 3.3378 16.2053
NCI-H1581 CTRP2 4.8547 8.1565 3.3276 7.5905
RERF-LC-A1 CTRP2 4.873 7.137 3.1572 2.8073
CAL-12T CTRP2; CTRP1 4.8794 6.4929 4.1873 4.0214
NCI-H460 CTRP2; CTRP1 4.9419 7.1528 3.9129 5.0428
HCC1359 CTRP1 5.0257 7.2542 3.9335 10.2663
HCC1833 CTRP2; CTRP1 5.0423 8.6918 3.2286 7.7167
NCI-H2110 CTRP1 5.1379 12.856 1.2259 27.9433
NCI-H2106 CTRP2 5.2297 9.4137 3.0121 8.187
T3M-10 CTRP1 5.23 8.5469 3.4554 13.5743
COR-L23 CTRP1 5.2489 9.1214 3.1837 15.709
NCI-H358 CTRP2 5.2534 11.2158 2.131 11.7824
NCI-H196 CTRP2 5.2589 9.3946 2.3354 5.7502
HCC2935 CTRP1 5.3102 8.0934 3.7456 10.7781
RERF-LC-Ad1 CTRP2 5.3135 6.2237 3.7897 0.149
RERF-LC-KJ CTRP1 5.3708 9.7609 2.9625 16.9166
HCC827 CTRP2; CTRP1 5.5292 7.9701 3.9743 3.724
HCC15 CTRP2; CTRP1 5.5965 9.5015 3.2682 6.5428
Sq-1 CTRP1 5.6644 8.1643 3.9773 7.4895
MOR/CPR CTRP2 5.6664 6.8401 3.7035 0.1928
HARA [Human squamous cell lung carcinoma] CTRP2 5.7122 8.6067 3.7845 4.1374
DMS 79 CTRP2 5.7249 10.7535 2.0006 6.4655
NCI-H1838 CTRP2 5.7561 8.1303 3.2289 1.4878
NCI-H292 CTRP2 5.8643 7.7606 3.4359 0.7375
NCI-H2030 CTRP2; CTRP1 6.2486 9.1795 3.8856 3.0496
NCI-H1755 CTRP1 6.2677 12.8618 2.1133 19.2513
HCC2108 CTRP2; CTRP1 6.2883 10.7806 3.1465 5.9421
BEN CTRP2 6.405 7.3029 4.7539 0.0958
NCI-H1734 CTRP2 6.4087 8.2449 3.4826 0.3588
NCI-H2023 CTRP1 6.4571 10.3658 3.4607 9.3163
HCC2279 CTRP2 6.4733 8.329 3.4774 0.3463
HCC1588 CTRP2 6.4951 7.9165 3.6313 0.11
NCI-H2405 CTRP2 6.5192 8.4083 3.4665 0.3514
NCI-H2291 CTRP2 6.5885 9.6647 3.0044 1.5433
NCI-H1915 CTRP1 6.6804 11.4147 3.1096 11.3245
HCC366 CTRP2 6.7695 9.9424 3.8399 2.5448
LCLC-103H CTRP2 6.7853 7.9927 4.652 0.1509
HCC95 CTRP2 6.8599 8.6311 4.4443 0.537
SHP-77 CTRP2 6.9687 8.3213 4.6043 0.1762
HCC1171 CTRP2 7.118 8.7026 3.5822 0.0762
A-549 CTRP2 7.2377 8.9975 4.4638 0.3343
HCC1195 CTRP1 7.2866 14.1188 2.2241 15.4413
HCC78 CTRP2 7.3627 8.9701 4.5221 0.2007
NCI-H650 CTRP2 7.4134 9.5235 4.3388 0.5211
NCI-H727 CTRP2 7.8722 9.8002 4.4189 0.2284
NCI-H1299 CTRP2 7.9246 9.6707 4.483 0.1393
⏷ Show the Full List of 80 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-10 CTRP2 6.0688 7.8407 3.4947 0.4718
TE-9 CTRP2 6.2823 7.6751 3.6382 0.1393
KYSE-140 CTRP2 6.7615 8.9785 3.353 0.4901
KYSE-180 CTRP2 6.967 8.5335 3.587 0.0886
COLO 680N CTRP2 7.816 9.3658 4.5486 0.0915
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COV434 CTRP1 0.0432 2.8354 -0.0049 68.5421
OVCAR-8 CTRP1 0.7912 5.8378 0.1676 57.0047
OVK18 CTRP1 1.3601 4.8212 1.0846 52.2838
OVKATE CTRP1 1.8861 4.6752 1.693 45.8887
JHOS-4 CTRP1 2.1473 4.672 1.978 42.3841
OV-90 CTRP1 2.3622 4.1687 2.3026 38.8954
RMUG-S CTRP1 2.763 5.879 2.2896 35.7389
Caov-3 CTRP1 2.8243 4.6056 2.7274 32.6033
A2780 CTRP1 2.9119 6.0119 2.4007 34.015
OVCAR-4 CTRP1 4.2194 10.4898 1.6155 30.2397
IGROV-1 CTRP1 4.3274 7.4541 3.2079 19.733
SNU-119 CTRP2 4.625 8.0685 2.5252 5.9798
RMG-I CTRP1 4.6998 10.0167 2.2748 24.4671
JHOC-5 CTRP2; CTRP1 4.8707 6.3141 4.2683 3.7017
SNU-840 CTRP1 5.0459 8.7209 3.217 16.2917
OAW42 CTRP1 5.0771 6.2285 4.4892 5.0599
TYK-nu CTRP1 5.1325 8.809 3.2448 15.7026
ES2 CTRP2 5.2628 6.6938 3.5846 0.7058
COV644 CTRP1 5.3431 10.2053 2.7185 18.7928
DOV13 CTRP2 5.3983 10.744 1.7783 7.9257
COV362 CTRP1 5.793 9.1161 3.6048 10.2326
OVISE CTRP2 5.9463 7.1702 3.6916 0.1384
OV7 CTRP1 6.1782 8.6513 4.0876 5.0496
OVMANA CTRP1 6.3287 9.7744 3.6569 8.1312
COV318 CTRP1 6.6878 10.2722 3.6523 7.1923
ONCO-DG-1 CTRP2 6.7223 9.9435 3.8117 2.6995
JHOM-1 CTRP1 6.7411 13.5809 2.1054 17.7594
EFO-27 CTRP1 6.8134 13.255 2.3149 16.2828
SNU-8 CTRP2 7.0335 8.6116 4.5244 0.291
OVTOKO CTRP2 7.4161 9.3103 4.4197 0.3556
Kuramochi CTRP2 7.6386 10.8977 3.8926 1.5847
OVSAHO CTRP2 7.6766 8.9101 4.6527 0.0342
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaTu 8902 CTRP1 3.3354 7.6559 2.1444 32.5383
KP-3 CTRP2 3.812 10.1314 0.833 15.0196
QGP-1 CTRP2 4.7539 9.1736 2.0762 7.7363
KP-4 CTRP2 5.4613 10.4309 2.6902 9.1031
SNU-213 CTRP2 5.8913 7.3642 3.6005 0.313
SUIT-2 CTRP2 6.0806 11.2576 2.7534 7.7877
HPAF-II CTRP2 6.862 8.7049 3.4909 0.2145
BxPC-3 CTRP2 7.3841 9.3162 4.4047 0.3958
CFPAC-1 CTRP2 7.5328 9.2426 4.4893 0.2076
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 CTRP2 4.7007 7.1207 3.7075 6.3199
ACC-MESO-1 CTRP2 7.2821 8.6712 4.5971 0.1205
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP1 3.6701 5.7517 3.3105 22.6129
22Rv1 CTRP2 5.2031 8.0648 2.9339 3.2798
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 5.7583 7.114 3.6395 0.2834
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 852.T CTRP1 2.5027 4.3643 2.4235 37.0298
A-375 CTRP2; CTRP1 2.9491 4.5635 2.8703 14.3113
SK-MEL-5 CTRP1 3.1034 5.1141 2.9094 29.3416
SK-MEL-1 CTRP2; CTRP1 5.3902 13.1274 1.2972 14.8716
SK-MEL-28 CTRP1 5.4166 9.4888 3.1345 15.4252
Mel Ho CTRP2 6.0741 7.6086 3.5834 0.2809
RPMI-7951 CTRP2 6.5425 7.9995 4.551 0.4388
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RKN CTRP1 4.1636 6.6233 3.4457 18.658
HT-1080 CTRP1 5.7345 9.7671 3.2414 13.3921
Rh41 CTRP2 7.1092 8.4768 4.6018 0.1476
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MKN74 CTRP1 3.7445 8.5246 2.1376 30.1285
NCI-N87 CTRP2 3.9956 7.6602 2.2239 8.555
AGS CTRP2; CTRP1 5.0214 6.4696 4.322 3.1673
SNU-668 CTRP2 5.1025 6.6554 3.5182 1.0729
SNU-5 CTRP2 5.5471 7.0732 3.5648 0.5701
MKN45 CTRP2 5.8992 7.2935 4.527 0.977
GSU CTRP2 5.9923 6.6796 4.8201 0.0983
MKN1 CTRP2 6.2275 8.0247 4.3864 1.1521
GSS CTRP2 6.4774 10.2031 3.5392 4.0361
SNU-620 CTRP2 6.4818 8.7523 4.2069 1.5298
SNU-719 CTRP2 6.7309 8.9957 3.3341 0.5438
NUGC-4 CTRP2 6.8385 8.5617 3.5322 0.1648
ECC12 CTRP2 6.9479 8.0029 4.707 0.0601
23132/87 CTRP2 7.1792 8.6151 4.5791 0.1629
KE-39 CTRP2 7.7361 10.3627 3.231 0.3927
SNG-M CTRP1 5.4669 7.9459 3.9397 8.4963
SNU-1077 CTRP2 7.3622 9.0091 4.508 0.2217
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8505C CTRP2 4.498 6.535 3.1867 3.2725
CAL-62 CTRP2 5.6869 7.2363 4.4265 1.5876
BHT-101 CTRP2 6.145 7.4906 3.6524 0.1489
TT CTRP2 6.2203 8.0549 3.4769 0.4448
B-CPAP CTRP2 6.5663 10.5121 3.451 4.2654
CGTH-W-1 CTRP2 6.8654 8.9111 4.3355 0.8205
8305C CTRP2 7.0952 13.5524 2.3544 7.849
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-9 CTRP1 5.3423 8.2775 3.6792 11.2293
YD-10B CTRP2 5.844 7.3105 3.6012 0.33
HSC-3 CTRP2 5.9523 7.2624 3.6612 0.182
SNU-46 CTRP2 6.1532 7.9776 3.4781 0.4716
Detroit 562 CTRP2 6.3655 14.9681 0.4088 11.9421
SNU-899 CTRP2 6.4263 7.6822 3.6865 0.0674
SNU-1076 CTRP2 6.6023 7.8701 4.6254 0.25
SNU-1214 CTRP2 6.7961 8.8369 3.4189 0.3484
BHY CTRP2 6.9973 9.5112 4.152 1.2708
SNU-1066 CTRP2 7.2969 8.801 4.5573 0.1667
SNU-1041 CTRP2 7.9748 9.3968 4.5923 0.0463
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TCCSUP CTRP2 4.8704 7.5553 2.9547 3.6803
253J-BV CTRP2 5.7755 7.1993 4.498 1.2105
CAL-29 CTRP2 6.0002 8.6119 3.9805 2.9285
253J CTRP2 6.11 8.338 4.1782 2.0255
639V CTRP2 6.3746 7.6752 4.6036 0.3962
5637 CTRP2 6.7435 8.5757 3.4924 0.2405
JMSU-1 CTRP2 6.791 8.6543 4.4042 0.6779
KU-19-19 CTRP2 6.7989 7.8723 4.6991 0.0885
BFTC-905 CTRP2 6.9705 8.3334 4.6007 0.1811
VM-CUB-1 CTRP2 7.7121 9.593 4.4323 0.2473
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug

References

1 A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma. ACS Chem Biol. 2012 Jul 20;7(7):1152-7.