Details of the Drug

General Information of Drug (ID: DMFYCQ1)

Drug Name

DBT-066

Synonyms

RAGE modulator (dementia), Digital Biotech

Indication

Disease Entry	ICD 11	Status	REF
Dementia	6D80-6D86	Investigative	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Advanced glycosylation end product receptor (AGER)	TTMO9HF	RAGE_HUMAN	Modulator	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Dementia

ICD Disease Classification

6D80-6D86

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Advanced glycosylation end product receptor (AGER)	DTT	AGER	7.92E-01	6.77E-03	0.04

Molecular Expression Atlas (MEA)

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2843).