Details of the Drug

General Information of Drug (ID: DMGANIC)

Drug Name
tamatinib
Synonyms R 406; R-406; R406 free base
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Clinical trial [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 470.5
Logarithm of the Partition Coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 11
Chemical Identifiers
Formula
C22H23FN6O5
IUPAC Name
6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
Canonical SMILES
CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C
InChI
InChI=1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,28,29,30)
InChIKey
NHHQJBCNYHBUSI-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11213558
ChEBI ID
CHEBI:91348
CAS Number
841290-80-0
UNII
RC3A285J2G
DrugBank ID
DB07159
TTD ID
D0S6TK
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Proto-oncogene c-Ret (RET) TT4DXQT RET_HUMAN Inhibitor [1]
Tyrosine-protein kinase SYK (SYK) TTOU65C KSYK_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Proto-oncogene c-Ret (RET) DTT RET 9.18E-01 -0.36 -0.48
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 143 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 3.3444 7.7847 2.0877 16.1338
JK1 CTRP2 8.2987 10.9894 4.1534 0.5529
JM1 CTRP2 2.1348 5.1094 1.8511 20.3775
EoL-1 CTRP2 -4.7386 -2.1031 -4.7393 65.0763
MV4-11 CTRP2 -4.6199 -2.2711 -4.6201 64.3379
MOLM-13 CTRP2 -3.3075 -0.9318 -3.3085 55.6295
MOLM-16 CTRP2; CTRP1 -1.4656 5.3957 -2.1562 44.5268
SEM CTRP2 -0.9141 3.3452 -1.0856 40.16
Pfeiffer CTRP2 -0.5735 1.361 -0.5765 37.437
Kasumi-1 CTRP2 -0.1376 3.9994 -0.3636 35.2311
SET-2 CTRP2 -0.0854 1.9617 -0.0929 34.2003
GDM-1 CTRP2; CTRP1 0.0303 3.8634 -0.1549 34.0637
Mono-Mac-6 CTRP2 0.4109 21.9863 -7.5417 43.068
Mono-Mac-1 CTRP2 0.4565 13.7636 -3.5496 39.4366
KMS-11 CTRP2; CTRP1 0.5006 5.7656 -0.1253 32.3563
OCI-AML-5 CTRP2 0.5823 3.8021 0.449 30.1741
KMS-26 CTRP2 0.7019 2.2873 0.6984 28.942
Ri-1 CTRP2 0.722 9.0192 -1.1385 34.3076
F-36P CTRP2 0.8463 6.5082 -0.0063 30.7857
OPM-2 CTRP2 0.9373 2.0066 0.9371 27.3625
NCI-H929 CTRP2 1.1705 5.2016 0.7727 27.177
OCI-M1 CTRP2 1.1882 1.8948 1.1882 25.6905
KMS-34 CTRP2 1.3499 3.8778 1.2607 24.9157
Daudi CTRP2 1.5475 3.6282 1.5014 23.4522
WSU-DLCL2 CTRP2; CTRP1 1.5591 3.9964 1.4683 23.6018
SUP-M2 CTRP2 1.7715 2.91 1.7697 21.8105
A3/Kawakami CTRP2 1.8688 2.9985 1.8666 21.1635
MOLP-8 CTRP2 1.8708 3.3988 1.8565 21.191
697 CTRP2 1.8927 4.3045 1.7749 21.3997
BL-70 CTRP2; CTRP1 1.8939 3.3217 1.884 21.0982
KO52 CTRP2 1.938 4.0383 1.8665 20.9378
RCH-ACV CTRP2 1.9565 9.7235 -0.1893 27.9941
L-540 CTRP2 1.9837 6.9123 1.0578 23.7187
M-07e CTRP2 2.026 10.4695 -0.4643 28.6198
TF-1 CTRP2 2.1212 4.9524 1.8789 20.319
SU-DHL-5 CTRP1 2.125 3.0047 2.1244 41.9168
GA-10 CTRP2 2.1318 4.5413 1.9877 19.8997
NU-DUL-1 CTRP2; CTRP1 2.2242 7.2185 1.1922 22.6172
Mino CTRP2 2.2628 4.7637 2.0806 19.1623
MOLT-3 CTRP2 2.2875 4.2659 2.207 18.641
JeKo-1 CTRP2 2.5364 6.322 1.8768 19.1068
KMS-28BM CTRP2 2.6832 5.7276 2.2533 17.2723
KMS-27 CTRP2 2.7499 6.0645 2.2029 17.2704
OCI-AML-3 CTRP2; CTRP1 2.7517 6.2964 2.1208 17.6553
L-428 CTRP2 2.8443 9.6282 0.7341 22.5427
SKM-1 CTRP2; CTRP1 2.8819 3.9511 2.8709 14.5264
HDLM-2 CTRP2 2.9382 12.435 -0.5254 26.4022
SU-DHL-4 CTRP2; CTRP1 2.9603 13.5379 -1.0354 27.8339
EB1 CTRP2 3.0343 6.6616 2.2668 16.2385
PL21 CTRP2; CTRP1 3.0439 9.7475 0.8789 21.5847
SIG-M5 CTRP2 3.0774 5.1379 2.8715 13.8279
MJ CTRP2 3.2026 10.3655 0.7274 21.6651
KMS-12-BM CTRP2 3.2365 10.3318 0.7758 21.4086
AML-193 CTRP2 3.2959 8.1103 1.889 17.0406
U-937 CTRP2; CTRP1 3.3502 6.4034 2.7104 13.7439
MOLP-2 CTRP2 3.4191 7.8386 2.1371 15.7506
Granta-519 CTRP2 3.4781 7.0953 2.5359 14.0133
DB CTRP2 3.5625 7.0813 2.6276 13.4327
SU-DHL-6 CTRP2 3.5935 13.6761 -0.5332 24.8516
Namalwa CTRP2 3.8596 6.6575 3.1191 10.7133
OCI-Ly3 CTRP2 3.9252 5.6762 3.6069 8.6218
EJM CTRP2; CTRP1 3.932 7.4283 2.8409 11.7402
KMS-18 CTRP2 3.9425 8.7425 2.2124 14.1917
DEL CTRP2 3.9602 7.0049 3.0602 10.699
HH [Human lymphoma] CTRP2 3.9773 15.1409 -0.9186 25.094
A4/Fukuda CTRP2 3.9986 10.2434 1.5291 16.7882
Hs 611.T CTRP2 4.0049 12.7874 0.2758 21.3492
PF-382 CTRP2 4.0681 10.4106 1.5098 16.7072
KHM-1B CTRP2 4.0732 13.8215 -0.1777 22.6767
THP-1 CTRP2; CTRP1 4.1122 6.1784 3.5963 8.25
MOTN-1 CTRP2 4.1609 8.9436 2.3171 13.2691
SUP-B15 CTRP2 4.2404 9.0906 2.3176 13.0904
HuT 78 CTRP2 4.2777 9.5148 2.142 13.7247
L-363 CTRP2 4.3478 9.9553 1.9867 14.2011
NOMO-1 CTRP2; CTRP1 4.3608 13.5936 0.1967 20.8952
NU-DHL-1 CTRP2 4.4141 12.057 0.9999 17.8894
KMS-21-BM CTRP2 4.6656 8.7545 2.8649 9.9146
TALL-1 [Human adult T-ALL] CTRP2 4.6818 10.406 2.0558 13.2174
RPMI-8226 CTRP2; CTRP1 4.8038 9.9454 2.3999 11.6395
ST486 CTRP2 4.8278 8.6794 3.0434 8.8361
SUP-T11 CTRP2 4.856 7.738 3.5375 6.707
NALM-6 CTRP2 4.8657 20.3682 -3.4138 26.3192
LP-1 CTRP2; CTRP1 4.9283 7.281 3.8372 5.3879
Karpas-620 CTRP2 4.9349 5.801 4.5714 2.2104
OCI-Ly19 CTRP2 5.0679 9.4605 2.8559 9.1464
HEL 92.1.7 CTRP2 5.1914 8.213 3.5808 5.8739
RL CTRP2 5.2168 9.6302 2.8935 8.7067
SR CTRP2 5.2392 11.8212 1.8169 13.0707
HPB-ALL CTRP2 5.4372 9.0298 3.3688 6.3195
RPMI-6666 CTRP2 5.5756 9.1244 3.4284 5.8333
EM-2 CTRP2 5.6516 10.2545 2.9264 7.7893
KMS-20 CTRP2 5.7667 10.8104 2.739 8.3663
Ci-1 CTRP2 5.7942 7.7773 4.2409 2.1747
KYO-1 CTRP2 5.8694 10.8307 2.8067 7.9148
Karpas-422 CTRP2 5.9309 9.6057 3.4537 5.1564
Kasumi-2 CTRP2 5.9447 16.0362 0.2796 17.4139
SUP-T1 CTRP2 5.9536 12.8468 1.8726 11.5469
HEL CTRP2 5.9588 7.1827 3.6918 0.1354
RPMI-8402 CTRP2 5.9801 9.2042 3.6832 4.1478
MOLM-6 CTRP2 6.0342 9.7094 3.4764 4.907
MC116 CTRP2 6.0628 9.3543 3.6678 4.0907
KM-H2 CTRP2 6.0755 8.9406 3.0489 1.8274
CML-T1 CTRP2 6.0984 9.054 3.8353 3.3714
SUP-HD1 CTRP2 6.1176 9.9564 3.415 5.0326
KE-37 CTRP2 6.1289 12.6867 2.0851 10.406
KE-97 CTRP2 6.1672 21.8733 -3.1372 23.3301
P12-Ichikawa CTRP2 6.2076 10.1425 3.3876 5.0122
OCI-Ly10 CTRP2; CTRP1 6.2864 13.0346 2.0421 10.3866
KMM-1 CTRP2 6.3384 9.5424 3.7607 3.3496
MHH-CALL-3 CTRP2 6.3642 22.1094 -2.4147 24.2426
HL-60 CTRP2 6.3714 7.9276 4.5011 0.6741
DND-41 CTRP2 6.3812 10.9844 3.1012 5.9142
JURL-MK1 CTRP2 6.3836 12.122 2.5501 8.1318
K-562 CTRP2 6.3949 9.0822 4.0091 2.3327
CMK CTRP2 6.4863 7.799 4.6041 0.3412
AMO1 CTRP2; CTRP1 6.5052 7.9345 4.5737 0.445
Toledo CTRP2 6.5638 8.3381 4.4254 0.7628
SU-DHL-1 CTRP2 6.5715 7.6793 4.6829 0.1587
Peer CTRP2 6.5855 9.4449 3.9571 2.3144
JJN-3 CTRP2 6.5987 10.8743 3.3008 4.8134
Reh CTRP2 6.6178 8.4765 4.3946 0.8154
Jurkat CTRP2 6.6328 15.1773 0.4937 11.1959
Karpas-299 CTRP2 6.6549 9.6712 3.8954 2.4652
NB4 CTRP2 6.7941 7.9078 4.6851 0.1053
OCI-AML-2 CTRP2 6.8476 7.9591 4.6866 0.0941
HT CTRP2 6.9186 8.4274 4.5464 0.2892
NCO2 CTRP2 6.9267 10.1827 3.8226 2.4429
MOLT-13 CTRP2 6.9981 13.9013 2.1195 8.9019
P31/FUJ CTRP2 7.0864 14.1141 2.0779 8.933
MOLT-16 CTRP2 7.1206 14.8564 1.7425 10.1649
U266B1 CTRP2 7.1291 13.2819 2.5067 7.209
Raji CTRP2 7.1368 8.4994 4.604 0.1391
HD-MY-Z CTRP2 7.1479 11.71 3.2588 4.2812
MM1.S CTRP2 7.214 8.715 4.5568 0.1862
ME1 CTRP2 7.2163 8.9248 4.482 0.3079
Ki-JK CTRP2 7.3464 8.9216 4.5332 0.1888
SK-MM-2 CTRP2 7.7294 9.4806 4.4783 0.1798
MHH-CALL-4 CTRP2 8.106 14.5178 2.5508 5.798
REC-1 CTRP2 8.5068 17.8175 1.2616 9.9691
SU-DHL-10 CTRP2 8.5484 21.8529 -0.649 16.1025
EHEB CTRP2 8.8505 19.9365 0.4816 12.1597
SU-DHL-8 CTRP2 9.482 20.9033 0.438 11.4734
P3HR-1 CTRP2 10.4962 23.2871 -0.0326 11.6902
⏷ Show the Full List of 143 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.0779 8.2658 0.5876 25.1177
TE15 CTRP2 2.3196 9.9995 0.0446 26.2601
OE21 CTRP2 1.4022 3.5613 1.3551 24.4235
EC-GI-10 CTRP2 2.1225 4.765 1.9273 20.1424
TE-11 CTRP2 3.5981 9.9201 1.3166 18.5327
TE-5 CTRP2 4.6647 8.7311 2.8758 9.871
TE-4 CTRP2 4.7758 8.5843 3.0459 8.9314
KYSE-410 CTRP2 4.8943 15.6092 -0.3636 21.5158
TE-6 CTRP2 4.8974 12.3368 1.275 15.852
TE-14 CTRP2 5.6385 22.5079 -3.1974 27.2161
KYSE-150 CTRP2 5.7255 10.8058 2.7098 8.5573
KYSE-180 CTRP2 6.3471 13.7013 1.0084 9.6197
KYSE-510 CTRP2 6.4616 12.7574 2.2957 9.0272
TE-9 CTRP2 6.6388 8.4284 4.4242 0.7168
KYSE-140 CTRP2 6.6999 20.2144 -1.2089 20.6176
TE-1 CTRP2 6.9808 9.4852 4.1546 1.2753
COLO 680N CTRP2 7.0505 17.566 0.3667 15.2149
KYSE-70 CTRP2 7.4292 10.9653 3.7557 2.195
OE33 CTRP2 7.5214 9.4697 4.4031 0.3509
KYSE-520 CTRP2 7.7303 9.5593 4.451 0.2159
TE-10 CTRP2 7.8462 15.3849 1.9812 8.2387
KYSE-30 CTRP2 8.0033 14.7389 2.3852 6.533
OE19 CTRP2 8.7957 18.5833 1.0878 10.1945
KYSE-450 CTRP2 11.5688 31.3198 -3.1342 18.4146
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 8.7574 16.168 2.1878 6.3641
HuP-T4 CTRP2 1.9093 13.7848 -2.1512 33.101
PaTu 8988s CTRP2 2.1428 5.7099 1.6739 20.9991
SW1990 CTRP2 2.4482 6.7016 1.6338 20.2712
BxPC-3 CTRP2 2.4816 8.7801 0.7682 23.3748
Capan-2 CTRP2 2.9404 7.0051 2.0237 17.4337
Panc 04.03 CTRP2 3.7009 7.0177 2.7959 12.4091
PaTu 8902 CTRP2; CTRP1 3.7337 5.8416 3.3431 10.2512
Panc 10.05 CTRP2 3.9449 7.4443 2.8388 11.6351
Panc 08.13 CTRP2 4.3519 11.2721 1.3361 16.7559
Panc 03.27 CTRP2 4.378 7.6488 3.1523 9.3397
MIA PaCa-2 CTRP2 4.6368 8.207 3.1118 8.9446
Capan-1 CTRP2 4.717 8.6543 2.9598 9.4119
HuP-T3 CTRP2 5.5459 10.7006 2.6226 9.2309
L3.3 CTRP2 5.9918 12.4786 2.0843 10.6411
PaTu 8988t CTRP2 6.1223 8.1802 4.2577 1.7151
SNU-213 CTRP2 6.1666 10.5985 3.1379 6.0849
PSN1 CTRP2 6.1869 10.3576 3.2692 5.5212
KP-3 CTRP2 6.3211 19.9996 -2.0925 20.3428
SNU-410 CTRP2 6.3227 13.9407 1.6115 11.9329
SU.86.86 CTRP2 6.5091 10.9977 3.1822 5.4067
QGP-1 CTRP2 6.7099 8.6206 4.3798 0.7961
KP-4 CTRP2 6.9704 12.3969 2.8228 6.1923
AsPC-1 CTRP2 7.0112 11.8599 3.1032 5.046
TCC-Pan2 CTRP2 7.018 8.3737 4.6043 0.1644
Panc 05.04 CTRP2 7.0217 13.9944 2.0909 8.9776
YAPC CTRP2 7.0965 8.1552 4.707 0.0451
CFPAC-1 CTRP2 7.1129 12.1688 3.0232 5.2253
HPAC CTRP2 7.3544 16.7089 1.0072 12.5155
Hs 766T CTRP2 7.3831 11.4216 3.5295 3.0232
Panc 02.03 CTRP2 7.4135 8.7389 4.6204 0.0784
SUIT-2 CTRP2 7.4995 8.887 4.6003 0.0853
PK-45H CTRP2 7.6922 9.4495 4.4756 0.191
PK-59 CTRP2 8.7128 16.0901 2.1967 6.3831
HPAF-II CTRP2 9.9032 26.2389 -1.8278 17.4372
DAN-G CTRP2 10.5668 37.1544 -6.6731 25.9981
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 9.2906 27.0577 -2.6555 20.2701
Hs 940.T CTRP2 2.4665 12.0045 -0.7633 28.2854
Hs 688(A).T CTRP2 3.8579 11.9097 0.5789 20.6381
WM983B CTRP2 4.1253 9.4625 2.0293 14.5176
Hs 895.T CTRP2 4.5582 10.7023 1.8007 14.4997
SK-MEL-24 CTRP2 4.5793 11.0644 1.6385 15.098
Hs 852.T CTRP2; CTRP1 4.7105 13.7751 0.4071 19.4445
G-361 CTRP2 4.9597 13.0789 0.9564 16.9177
A-375 CTRP2; CTRP1 4.9885 8.0265 3.5161 6.6155
IGR-1 CTRP2 5.236 9.0091 3.2194 7.3078
HMCB CTRP2 5.2734 7.0189 4.2409 2.9601
SK-MEL-1 CTRP2; CTRP1 5.3317 7.1524 4.2298 2.9896
RPMI-7951 CTRP2 5.3372 10.6369 2.4882 10.1643
CJM [Human melanoma] CTRP2 5.4007 9.4417 3.1352 7.3603
Hs 934.T CTRP2 5.5866 11.8086 2.1029 11.279
Hs 839.T CTRP2 6.0876 16.7511 0.0361 17.9606
SK-MEL-2 CTRP2 6.1608 7.1243 4.7236 0.2205
LOX-IMVI CTRP2 6.2129 10.3602 3.2861 5.4146
SK-MEL-3 CTRP2 6.2202 11.7687 2.6047 8.1685
IGR-39 CTRP2 6.2252 10.4986 3.2277 5.6328
SK-MEL-5 CTRP2; CTRP1 6.3929 9.3726 3.8865 2.8673
Hs 944.T CTRP2 6.4019 9.3478 3.8913 2.7683
Hs 294T CTRP2 6.426 11.3015 2.979 6.3405
A2058 CTRP2 6.4475 7.5555 4.6795 0.2018
HT-144 CTRP2 6.4841 8.2516 4.4223 0.8277
UACC-257 CTRP2 6.5644 11.7996 2.8343 6.7184
WT2-iPS CTRP2 6.5986 7.7434 4.6702 0.1715
SK-MEL-31 CTRP2 6.6313 12.0811 2.7447 6.9783
Mel Ho CTRP2 6.6624 14.0449 1.0566 8.9559
IGR-37 CTRP2 6.688 10.0958 3.7215 3.0742
A101D CTRP2 6.703 8.0686 4.5924 0.2776
MeWo CTRP2 6.8274 15.4059 1.264 12.4122
SK-MEL-30 CTRP2 6.9506 7.9285 4.7328 0.0406
Hs 936.T CTRP2 7.0504 8.2462 4.6604 0.0898
Mel JuSo CTRP2 7.1572 8.7092 4.5373 0.2306
K029AX CTRP2 7.1874 8.2804 4.6963 0.0443
IPC-298 CTRP2 7.1901 8.2532 4.7061 0.038
COLO 800 CTRP2 7.2491 10.2939 3.9495 1.7117
WM793 CTRP2 7.3598 9.1546 4.4546 0.3106
COLO 829 CTRP2 7.5415 18.1298 0.448 14.163
WM88 CTRP2 8.1464 14.6261 2.5256 5.8435
MDA-MB-435S CTRP2 8.225 15.7351 2.0601 7.4586
UACC-62 CTRP2 8.5655 17.0291 1.6707 8.4427
WM1799 CTRP2 8.5907 18.0171 1.2219 9.9973
WM266-4 CTRP2 8.7942 15.1718 2.6588 4.6641
WM115 CTRP2 8.8793 17.0717 1.8467 7.4349
SK-MEL-28 CTRP2; CTRP1 8.9269 17.5724 1.6567 8.1096
COLO 792 CTRP2 9.3103 20.7867 0.3814 11.876
RVH-421 CTRP2 11.2436 29.5585 -2.5107 17.3986
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 CTRP2 1.5095 2.9444 1.5037 23.5691
IMR-32 CTRP2 1.7467 4.1881 1.638 22.3405
NH-6 CTRP2 2.0342 4.7051 1.8453 20.7078
SK-N-DZ CTRP2 2.7144 5.6572 2.3113 16.9656
SK-N-BE(2) CTRP2 4.6383 10.3284 2.0567 13.3035
SK-N-AS CTRP2 5.4544 9.2167 3.2893 6.6215
SK-N-SH CTRP2 5.811 12.1839 2.0917 10.9245
Kelly CTRP2 6.7276 8.4779 4.4455 0.6056
CHP-126 CTRP2 7.0829 13.8619 2.1971 8.4771
NB1 CTRP2 7.4408 8.6911 4.6458 0.0558
KP-N-YN CTRP2 8.0969 9.7731 4.5087 0.0921
KP-N-SI9s CTRP2 8.8532 20.3965 0.2636 12.8634
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -1.9994 1.5513 -2.0403 46.9863
HuH-28 CTRP2 0.3878 3.0052 0.341 31.1789
SNU-478 CTRP2 3.5411 10.0754 1.1877 19.1566
HuCC-T1 CTRP2 5.1623 9.8135 2.7574 9.3767
SNU-308 CTRP2 5.9999 12.7408 1.9606 11.1191
SNU-1196 CTRP2 6.5053 13.0793 2.1698 9.4573
SNU-869 CTRP2 7.8229 14.0232 2.6052 5.933
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MG-63 CTRP2 2.1786 5.7041 1.7147 20.7436
SK-ES-1 CTRP2 2.844 8.8867 1.0809 21.285
U2OS CTRP2; CTRP1 3.1994 8.9845 1.3916 19.2875
SJSA-1 CTRP2 3.8963 7.8882 2.5805 12.8027
TC71 CTRP2 4.0378 10.2769 1.5482 16.6253
A-673 CTRP2 4.409 7.4357 3.2852 8.7196
SaOS-2 CTRP2 4.8011 11.5556 1.5839 14.8549
HOS CTRP2 5.1888 9.2975 3.0369 8.1597
CAL-78 CTRP2 5.2282 17.4986 -1.0302 22.8094
G-292 clone A141B1 CTRP2 5.2447 13.4114 1.0266 16.0954
SK-N-MC CTRP2 5.9942 7.3216 4.566 0.7593
SW1353 CTRP2 6.2146 8.0026 4.3891 1.1548
Hs 822.T CTRP2 6.421 15.251 1.038 13.9129
Hs 888.T CTRP2 6.4617 19.6832 -1.13 20.8106
MHH-ES-1 CTRP2 11.455 26.2481 -0.8101 12.8135
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-85-1 CTRP2 3.1528 10.0576 0.8281 21.427
MDA-MB-415 CTRP2 4.2809 9.2358 2.2827 13.1443
MCF-7 CTRP2; CTRP1 4.4625 7.7097 3.2087 9.0011
CAL-120 CTRP2 4.8725 11.2963 1.7741 13.9603
AU565 CTRP2 5.0417 9.3895 2.8696 9.1397
Hs 578T CTRP2 5.2589 9.465 3.0102 8.1409
HMC-1-8 CTRP2 5.3915 11.5886 1.3604 9.7168
EFM-192A CTRP2 5.4508 10.2532 2.7704 8.7898
KPL-1 CTRP2 5.7979 15.3288 0.5159 16.8763
HCC1806 CTRP2 5.9538 10.9795 2.7965 7.8175
BT-20 CTRP2 6.0402 10.5912 3.0507 6.6366
SK-BR-3 CTRP2 6.1871 8.5283 4.1375 2.0891
HCC1143 CTRP2 6.335 13.9754 1.6035 11.9429
HCC1395 CTRP2 6.356 14.6607 1.2808 13.1287
MDA-MB-361 CTRP2 6.4682 12.4455 2.4529 8.3902
HCC1954 CTRP2 6.4747 16.9188 0.253 16.5614
CAL-51 CTRP2 6.5416 12.3693 2.5422 7.9205
HCC2218 CTRP2 6.5809 11.7527 2.8684 6.558
CAL-148 CTRP2 6.6731 8.0833 4.5747 0.3253
HCC1937 CTRP2 6.7525 14.4449 1.6805 10.9681
MDA-MB-453 CTRP2 6.7661 11.562 3.0845 5.4405
JIMT-1 CTRP2 6.8491 8.3275 4.5554 0.2966
Hs 578Bst CTRP2 6.8496 16.3832 0.8001 14.0507
ZR-75-1 CTRP2 6.8527 8.3163 4.561 0.2845
HCC1419 CTRP2 6.9827 8.4704 4.556 0.2506
BT-474 CTRP2 7.0426 8.5283 4.5583 0.2287
HCC38 CTRP2 7.1726 9.1625 4.3744 0.5497
MDA-MB-231 CTRP2 7.3001 16.028 1.3 11.5414
CAMA-1 CTRP2 7.3019 9.4528 4.3182 0.6196
HCC1500 CTRP2 7.5877 13.9057 2.5116 6.5789
BT-549 CTRP2 7.5921 9.1521 4.5425 0.129
MDA-MB-468 CTRP2 7.8252 9.4158 4.5349 0.1024
T-47D CTRP2 7.9223 17.071 1.2275 10.8905
MDA-MB-157 CTRP2 8.3036 21.4926 -0.6471 16.4561
HCC1428 CTRP2 11.2096 23.7931 0.1736 10.2547
ZR-75-30 CTRP2 11.6458 28.9797 -1.9702 15.6219
BT 440 CTRP2 -0.6254 3.4908 -0.7988 38.2789
BT 416 CTRP2 0.4751 4.3335 0.2323 31.2475
BT 482 CTRP2 1.6294 10.4256 -0.8383 30.7847
BT 179 CTRP2 1.8541 4.7182 1.6461 21.9737
BT 271 CTRP2 2.404 13.8043 -1.6924 30.8146
BT 286 CTRP2 2.9268 6.7572 2.1144 17.1192
BT 504 CTRP2 2.9949 8.1005 1.5934 18.9577
BT 172 CTRP2 4.0546 8.0202 2.6683 12.0725
BT 330 CTRP2 4.4659 9.4422 2.3466 12.4826
BT 139 CTRP2 5.0861 8.3783 3.4121 6.7806
BT 131 CTRP2 5.1061 10.8944 2.1706 11.9036
BT 444 CTRP2 5.4574 14.2302 0.7909 16.5445
BT 159 CTRP2 5.6536 9.8232 3.1418 6.8926
BT 498 CTRP2 5.9145 10.1824 3.1596 6.3894
BT 333 CTRP2 6.3814 11.4496 2.876 6.8219
BT 428 CTRP2 6.4776 12.5976 2.3854 8.6451
BT147 CTRP2 6.5095 18.4655 -0.4877 18.8604
BT164 CTRP2 6.6151 7.5691 4.7377 0.0766
BT 112 CTRP2 6.7656 8.1353 4.5929 0.2546
BT 145 CTRP2 6.9616 10.7419 3.5905 3.252
BT 224 CTRP2 6.9987 8.0633 4.7043 0.0567
BT 239 CTRP2 7.2287 14.9406 1.7772 9.8723
BT 232 CTRP2 7.3277 17.3219 0.6889 13.6743
BT 422 CTRP2 7.3731 15.4707 1.6212 10.2459
BT 231 CTRP2 7.5765 14.9387 2.0151 8.4767
BT 328 CTRP2 7.6248 20.5379 -0.6712 17.5643
BT 216 CTRP2 8.4902 19.3567 0.5164 12.5402
BT 228 CTRP2 8.5714 17.8974 1.266 9.8687
BT 340 CTRP2 8.6992 19.2705 0.6982 11.6461
BT 245 CTRP2 9.1383 28.2391 -3.3433 21.9978
BT 359 CTRP2 9.8136 21.9098 0.1779 11.8781
BT 320 CTRP2 10.9604 23.7078 0.0611 10.8697
BT 187 CTRP2 11.236 24.7279 -0.2407 11.4488
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.0877 13.0946 2.5685 7.0256
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 1.6828 3.7552 1.6308 22.571
SNU-489 CTRP2 2.0077 3.5927 1.9865 20.302
GaMG CTRP2; CTRP1 2.9529 7.1496 1.9803 17.6465
SW1088 CTRP2 3.4795 9.6238 1.3482 18.6947
CAS-1 CTRP2 3.8848 10.9294 1.0873 18.7334
Hs 683 CTRP2 4.231 8.0135 2.8373 10.9734
SNB-75 CTRP2 4.3022 10.9001 1.4771 16.3196
SF539 CTRP2 4.5226 13.5548 0.3469 19.9806
42-MG-BA CTRP2 5.1115 11.535 1.8549 13.166
KG-1-C CTRP2 5.5605 14.0142 0.982 15.656
M059K CTRP2 5.6291 8.8648 3.5969 5.0443
YKG-1 CTRP2 5.6632 9.4683 3.3245 6.1178
A-172 CTRP2 5.6923 10.5208 2.8256 8.1364
KNS-42 CTRP2 5.8415 10.11 3.1413 6.5826
SNU-626 CTRP2 6.0792 11.7928 2.4889 8.8657
SNU-466 CTRP2 6.106 12.3081 2.2549 9.7657
LN-229 CTRP2; CTRP1 6.1279 12.4901 2.1922 10.053
KNS-81 CTRP2 6.264 8.505 4.1938 1.7956
SNU-201 CTRP2 6.3502 11.8028 2.682 7.6524
T98G CTRP2 6.3724 12.363 2.4242 8.6548
SF268 CTRP2 6.4902 15.1953 1.1177 13.5048
SF295 CTRP2 6.5973 8.1221 4.5273 0.4687
SW1783 CTRP2 6.6015 12.3227 2.6071 7.5714
U-118MG CTRP2 6.6146 18.0666 -0.2089 17.8172
U-87MG ATCC CTRP2 6.7248 8.6517 4.3742 0.8023
CCF-STTG1 CTRP2 6.7387 8.0949 4.597 0.2561
ONS-76 CTRP2 6.7607 11.8342 2.9513 5.9735
GB-1 CTRP2 6.8032 18.4655 -0.2627 17.6646
GMS-10 CTRP2 6.8322 13.1555 2.3648 8.1887
DK-MG CTRP2 6.8388 12.4157 2.7257 6.7559
KNS-60 CTRP2 6.9212 14.6617 1.696 10.6455
LN-18 CTRP2 6.9443 8.0271 4.6976 0.0688
NMC-G1 CTRP2 7.0324 8.4114 4.5963 0.1725
YH-13 CTRP2 7.1146 12.8688 2.6938 6.5005
8-MG-BA CTRP2 7.426 12.6448 2.998 4.9352
U-251MG CTRP2 7.9912 14.744 2.3752 6.5847
Becker CTRP2 8.0226 15.8824 1.861 8.4505
TM-31 CTRP2 8.3024 15.2506 2.3332 6.3649
DBTRG-05MG CTRP2 8.635 18.3592 1.0889 10.4012
SNU-1105 CTRP2 9.1923 18.6166 1.3249 8.8814
GOS-3 CTRP2 9.6077 17.2369 2.2 5.4225
KALS-1 CTRP2 11.0213 25.6986 -0.8279 13.3675
Daoy CTRP2 11.056 23.1627 0.3698 9.83
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 0.2396 4.0121 0.0438 32.7161
JHUEM-3 CTRP2 1.8931 6.2655 1.2087 23.4348
ESS-1 CTRP2 2.6873 4.2449 2.6381 15.8701
HEC-151 CTRP2; CTRP1 2.8312 5.2016 2.5873 15.6841
MFE-296 CTRP2 3.5256 9.8174 1.2983 18.7748
KLE CTRP2; CTRP1 4.9886 8.9881 3.0354 8.6306
AN3-CA CTRP2 5.5696 10.5041 2.739 8.7082
HEC-6 CTRP2 5.8053 7.0393 3.6852 0.1833
HEC-265 CTRP2 5.8567 6.8294 3.7766 0.0574
JHUEM-1 CTRP2 5.8947 10.6263 2.9265 7.3804
EN CTRP2 6.1493 7.6866 4.4908 0.8736
JHUEM-7 CTRP2 6.255 10.5811 3.2085 5.6663
HEC-251 CTRP2 6.5126 8.7295 3.3435 0.6212
HEC-108 CTRP2; CTRP1 6.6005 10.2314 3.6167 3.6482
HEC-50B CTRP2 6.7724 13.7381 2.0399 9.551
MFE-319 CTRP2 6.9447 9.2846 4.2204 1.1012
HEC-1-A CTRP2 7.087 14.1451 2.0634 8.9877
EFE-184 CTRP2 7.3107 14.7078 1.9461 9.1124
RL95-2 CTRP2 7.6815 15.5494 1.7938 9.1615
HEC-59 CTRP2; CTRP1 8.125 13.3907 3.0856 3.9067
HEC-1-B CTRP2 9.7456 21.7079 0.2292 11.8032
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 4.0302 5.938 3.6158 8.3887
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 0.2097 4.5338 -4.4964 4.9844
CAL-54 CTRP2 0.8126 2.8785 0.7919 28.2622
KMRC-2 CTRP2 1.6694 6.0908 1.0304 24.7404
UO-31 CTRP2 2.2671 11.1627 -0.5537 28.2203
Caki-1 CTRP2 3.8704 8.9757 2.0314 15.0888
TUHR10TKB CTRP2 4.1331 8.7278 2.3973 13.0041
VMRC-RCZ CTRP2 5.3791 13.9255 0.8796 16.3744
BFTC-909 CTRP2 5.5231 9.0814 3.4096 6.0006
KMRC-1 CTRP2 5.7175 9.1207 3.5363 5.1518
769-P CTRP2 5.8177 13.8734 1.2567 14.1624
TUHR4TKB CTRP2 5.913 14.0372 1.2498 14.0166
KMRC-20 CTRP2 6.1622 12.2406 2.3301 9.3708
OS-RC-2 CTRP2 6.2126 9.1923 3.8445 3.1842
RCC10RGB CTRP2; CTRP1 6.2891 13.2465 1.9397 10.7853
SNU-1272 CTRP2 6.3146 12.6989 2.2172 9.5742
VMRC-RCW CTRP2 6.3589 12.5788 2.3086 9.1383
A-498 CTRP2 6.6223 7.9622 4.5992 0.2946
786-O CTRP2 6.8625 10.974 3.423 4
Caki-2 CTRP2 8.5994 15.1023 2.5783 5.1486
ACHN CTRP2 8.7615 19.219 0.7641 11.3409
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KM12 CTRP2; CTRP1 0.5998 5.238 0.1424 31.1889
SW48 CTRP2 0.8025 4.2429 0.6067 28.9219
SNU-C1 CTRP2 1.7228 3.716 1.6774 22.282
SNU-1040 CTRP1 2.2756 3.7515 2.2546 39.8941
LS180 CTRP2; CTRP1 2.5108 5.1976 2.239 17.9138
COLO 678 CTRP2; CTRP1 2.8576 8.1959 1.4185 20.0571
SNU-175 CTRP1 2.9349 6.0701 2.4033 33.8334
RCM-1 [Human ESC] CTRP2; CTRP1 3.3775 7.918 2.0659 16.2151
NCI-H716 CTRP2 3.6284 8.2882 2.1312 15.2599
LoVo CTRP2; CTRP1 3.6339 12.7368 -0.0239 23.2448
SW620 CTRP2; CTRP1 3.7528 10.2589 1.3037 18.2917
SW948 CTRP2; CTRP1 3.8283 5.9196 3.4118 9.7269
SNU-81 CTRP1 4.0496 7.3058 3.0134 22.7195
SW480 CTRP1 4.0617 8.9297 2.2405 27.8159
HCT 116 CTRP2; CTRP1 4.0834 6.0288 3.6322 8.1834
RKO CTRP2; CTRP1 4.2114 7.0084 3.3115 9.1539
HT-55 CTRP2; CTRP1 4.2944 6.1666 3.7863 7.0277
SNU-C4 CTRP2; CTRP1 4.3037 6.6171 3.5866 7.8115
CW-2 CTRP2; CTRP1 4.3458 5.8932 3.9611 6.199
SNU-C5 CTRP2; CTRP1 4.4647 8.0281 3.0541 9.6376
HCT 8 CTRP2; CTRP1 4.472 7.8477 3.1495 9.2256
T84 CTRP2 4.4788 13.1545 0.5089 19.5155
COLO 320 CTRP2; CTRP1 4.5929 13.5527 0.4177 19.654
SK-CO-1 CTRP2 4.7433 9.3049 2.6583 10.6146
SW1116 CTRP2 4.7631 10.8491 1.9044 26.1665
NCI-H508 CTRP2; CTRP1 4.8081 6.6741 4.0338 4.8139
HT115 CTRP2; CTRP1 4.9262 7.6969 3.6277 6.2705
CL-34 CTRP1 5.0459 7.2099 3.9725 9.8338
CL-40 CTRP1 5.1534 9.3022 3.0155 17.4079
CL-11 CTRP2 5.1856 15.1719 0.0978 19.4603
SNU-407 CTRP2 5.2556 12.2359 1.6231 13.8035
HT-29 CTRP2; CTRP1 5.2781 8.9694 3.2831 7.0436
LS123 CTRP2; CTRP1 5.31 8.8097 3.3884 6.5447
C2BBe1 CTRP2 5.4727 10.1604 2.834 8.4867
SNU-61 CTRP2; CTRP1 5.4746 9.3516 3.2484 6.8363
GP2d CTRP2 5.8437 8.4681 3.9442 3.2902
SW1417 CTRP2 5.8824 8.9057 3.7597 3.9811
LS513 CTRP2 6.1351 9.3799 3.7044 3.8421
DLD-1 CTRP2 6.2089 7.2755 4.6864 0.2812
OUMS-23 CTRP2 6.3687 7.3741 4.7147 0.1643
HCC-56 CTRP2 6.5536 7.8385 4.6173 0.2843
LS411N CTRP2 6.7225 8.1724 4.5616 0.3327
LS1034 CTRP2 6.8363 10.7379 3.5162 3.6761
COLO205 CTRP2 6.8685 8.1934 4.612 0.1904
COLO201 CTRP2 7.174 8.4197 4.6448 0.0873
MDST8 CTRP2; CTRP1 7.1794 11.6495 3.3183 4.0871
CCK-81 CTRP2 7.21 8.7962 4.5262 0.2337
SNU-503 CTRP2 7.2228 14.5229 1.9748 9.1298
HCT 15 CTRP2 7.3365 13.5368 2.5229 6.8644
SNU-C2A CTRP2 8.7394 24.6547 -1.8779 19.177
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Li-7 CTRP2 -0.1442 3.6351 -0.3049 35.0769
SNU-886 CTRP2 0.6535 2.2952 0.6493 29.2666
JHH-2 CTRP2 1.2729 3.4033 1.234 25.2569
SNU-449 CTRP2; CTRP1 1.8685 4.5855 1.694 21.8347
HuH-6 CTRP2 3.3119 9.8191 1.0946 20.0576
SNU-878 CTRP2 3.6979 7.1553 2.7299 12.6815
SNU-387 CTRP2 3.7072 10.1223 1.3201 18.2631
SNU-398 CTRP2; CTRP1 4.3432 6.9288 3.4764 8.1673
JHH-5 CTRP2 4.3786 7.826 3.0661 9.6957
SNU-423 CTRP2 4.847 9.3072 2.7463 10.0383
SNU-475 CTRP2 5.2249 6.4947 4.4636 2.1145
JHH-6 CTRP2; CTRP1 5.7272 9.3997 3.4172 5.7066
HuH-1 CTRP2 5.949 7.8965 4.2831 1.8175
SNU-761 CTRP2 6.1394 14.1905 1.3488 13.2454
JHH-1 CTRP2 6.2694 7.6179 4.5787 0.5209
HLF CTRP2 6.3556 8.7875 4.1197 1.9676
Hep 3B2.1-7 CTRP2 6.4043 8.4622 4.2915 1.3124
JHH-4 CTRP2 6.5624 12.852 2.322 8.7654
Hep-G2 CTRP1 7.0412 12.6304 2.7704 12.6717
PLC/PRF/5 CTRP2 7.2846 9.5662 4.2663 0.757
SK-HEP-1 CTRP2 8.2603 13.1505 3.2537 3.1347
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 153 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H3255 CTRP1 -0.1862 3.5316 -0.3322 68.6616
NCI-H1703 CTRP2 0.3586 3.5491 0.2477 31.5861
PC-14 CTRP2 0.4969 2.2145 0.4923 30.3115
NCI-H2073 CTRP1 0.5032 3.0122 0.4617 63.5666
EPLC-272H CTRP2 0.6572 8.0807 -0.8144 33.7099
NCI-H1650 CTRP2 0.7634 3.5523 0.6792 28.8039
DV-90 CTRP2 0.7986 2.19 0.797 28.2913
NCI-H1755 CTRP2; CTRP1 0.8337 8.5742 -0.8281 33.2295
NCI-H1666 CTRP2 0.9426 9.3961 -1.0732 33.4491
NCI-H1341 CTRP2 1.108 3.6631 1.0318 26.4824
LOU-NH91 CTRP2 1.309 6.0251 0.6634 27.1227
NCI-H647 CTRP2 1.3218 4.2057 1.1762 25.2975
LXF 289 CTRP2; CTRP1 1.352 4.1755 1.2159 25.1357
NCI-H1581 CTRP2 1.412 6.8966 0.4559 27.514
NCI-H2009 CTRP2; CTRP1 1.4661 4.793 1.2072 24.8058
SK-LU-1 CTRP2; CTRP1 1.5237 6.2877 0.8071 26.0383
HCC827 CTRP1 1.6353 3.7914 1.5771 48.969
HCC15 CTRP2; CTRP1 1.6972 5.3851 1.2962 23.7779
DMS 114 CTRP2 1.766 3.7814 1.7159 22.0103
NCI-H1963 CTRP1 1.9734 6.8246 1.0864 46.0993
NCI-H2286 CTRP2; CTRP1 2.3213 7.2313 1.2885 21.9904
NCI-H358 CTRP2 2.3356 9.6766 0.2105 25.679
COR-L105 CTRP2 2.5303 5.7017 2.0968 18.2997
EKVX CTRP2 2.5316 8.0036 1.1677 21.7887
NCI-H1781 CTRP1 2.5555 6.1916 1.9514 38.957
CAL-12T CTRP1 2.5651 6.3207 1.9125 39.0398
NCI-H596 CTRP1 2.5925 6.2344 1.9747 38.567
HCC2935 CTRP2; CTRP1 2.6187 6.5879 1.8646 18.9993
NCI-H446 CTRP2 2.7627 8.5954 1.1343 21.2988
T3M-10 CTRP2; CTRP1 2.8099 5.4881 2.4752 16.1586
COR-L51 CTRP1 2.9879 10.1607 0.6279 40.1164
HOP-62 CTRP2 3.0265 11.332 0.0933 24.2669
NCI-H226 CTRP2 3.0913 6.6508 2.3309 15.8361
NCI-H1563 CTRP2 3.1153 11.8582 -0.0788 24.5998
HCC1833 CTRP2; CTRP1 3.3228 13.5165 -0.6915 26.0054
NCI-H211 CTRP2 3.3508 9.4681 1.3004 19.1884
NCI-H2170 CTRP2 3.3967 7.0846 2.4581 14.5314
HCC4006 CTRP2; CTRP1 3.424 8.2128 1.9745 16.4614
NCI-H524 CTRP2 3.5354 5.8466 3.1256 11.5505
NCI-H841 CTRP2; CTRP1 3.6395 9.0728 1.7738 16.7331
HOP-92 CTRP2 3.693 12.7029 0.0378 22.8469
Sq-1 CTRP2; CTRP1 3.7185 7.7299 2.4901 13.6774
LK2 CTRP2 3.746 13.6589 -0.3876 24.0634
NCI-H441 CTRP2; CTRP1 3.7471 8.7184 2.0469 15.3925
NCI-H2030 CTRP2; CTRP1 4.0001 10.1798 1.5701 16.6984
HCC2108 CTRP2; CTRP1 4.0286 8.8961 2.226 14.0174
HCC1438 CTRP2 4.0586 8.8862 2.2507 13.7706
NCI-H1435 CTRP2; CTRP1 4.0868 13.3342 0.0856 21.8612
NCI-H2081 CTRP1 4.1943 7.8975 2.8674 23.0245
NCI-H322 CTRP2 4.1977 6.8297 3.3756 8.84
HCC366 CTRP2 4.2317 8.6765 2.5134 12.3064
NCI-H2122 CTRP2; CTRP1 4.2424 6.7505 3.4637 8.4591
NCI-H1876 CTRP1 4.2846 8.5031 2.6554 24.0455
NCI-H1693 CTRP2 4.297 9.4871 2.1731 13.556
COLO 668 CTRP2; CTRP1 4.3499 9.0692 2.4361 12.4437
Calu-3 CTRP2 4.5045 10.5183 1.8454 14.4341
SK-MES-1 CTRP2 4.5103 9.4311 2.3915 12.2036
SCLC-21H CTRP1 4.5256 5.5316 4.3035 9.3951
NCI-H838 CTRP2 4.6311 8.5541 2.9342 9.6977
NCI-H1355 CTRP2 4.8864 16.6176 -0.8744 23.0479
NCI-H522 CTRP2 4.945 9.1143 2.926 9.0929
NCI-H1694 CTRP2; CTRP1 4.9698 12.2941 1.3668 15.4268
Lu-65 CTRP2 4.9762 9.2075 2.9057 9.1168
COR-L88 CTRP2 5.0589 7.4307 3.8633 4.9367
COR-L23 CTRP1 5.0652 6.0495 4.5688 4.391
NCI-H2172 CTRP2; CTRP1 5.0831 9.2027 3.0071 8.5655
COLO 699 CTRP2; CTRP1 5.1077 15.0056 0.1261 19.5825
Lu-99 CTRP2 5.1338 10.052 2.6147 10.0241
NCI-H292 CTRP2 5.2109 10.9528 2.2278 11.4696
NCI-H1836 CTRP1 5.2499 7.3418 4.0725 8.1236
HARA [Human squamous cell lung carcinoma] CTRP2 5.2522 10.4916 2.492 10.3075
NCI-H1793 CTRP2 5.2714 16.1673 -0.329 20.6569
NCI-H1568 CTRP2 5.2743 12.7592 1.3769 14.7205
RERF-LC-KJ CTRP1 5.3101 8.3445 3.6204 11.8581
DMS 53 CTRP2 5.3892 13.4576 1.1216 15.4646
NCI-H1734 CTRP2 5.4082 17.2603 -0.7632 21.6975
LUDLU-1 CTRP2 5.5569 9.0338 3.4591 5.737
LCLC-97TM1 CTRP2 5.5952 20.2839 -2.1214 24.9297
SW1271 CTRP2 5.6247 11.4542 2.3094 10.3744
NCI-H1339 CTRP2 5.6257 9.2285 3.4148 5.8055
NCI-H1155 CTRP2 5.735 9.0754 3.5715 4.9785
NCI-H2110 CTRP2; CTRP1 5.7635 12.6255 1.8456 12.0603
NCI-H23 CTRP2 5.8902 8.1849 4.1107 2.5608
RERF-LC-Ad1 CTRP2 5.9074 7.7546 4.3232 1.7148
ChaGo-K-1 CTRP2 5.9224 10.5867 2.9666 7.1702
NCI-H520 CTRP2 5.9343 9.966 3.2801 5.8628
NCI-H460 CTRP2; CTRP1 5.9621 7.5757 4.4496 1.2535
NCI-H196 CTRP2 5.9983 11.7424 2.4533 9.1443
DMS 79 CTRP2 6.0239 7.8619 3.4673 0.5608
NCI-H2085 CTRP2 6.0293 17.6502 -0.4577 19.623
HCC1359 CTRP1 6.0376 8.4043 4.1145 5.2022
NCI-H1930 CTRP1 6.0457 8.7892 3.9382 6.6427
COR-L95 CTRP2 6.0563 9.1077 3.7816 3.643
NCI-H1105 CTRP2; CTRP1 6.1367 12.3305 2.2776 9.6969
COR-L47 CTRP2 6.1433 11.4306 2.7144 7.8463
NCI-H526 CTRP2 6.1868 9.204 3.8222 3.3053
HCC1171 CTRP2 6.2216 26.5469 -4.7423 29.0454
NCI-H2196 CTRP2 6.2282 8.323 4.2549 1.6119
HCC1195 CTRP2; CTRP1 6.2292 12.3842 2.3199 9.3751
EBC-1 CTRP2 6.2292 9.4692 3.7244 3.6349
HCC78 CTRP2 6.2797 10.8141 3.1129 6.0165
NCI-H1838 CTRP2 6.2802 11.2513 2.9008 6.8752
SBC-5 CTRP2 6.3004 7.1615 4.7649 0.1038
NCI-H2106 CTRP2 6.3117 10.6377 3.2205 5.5348
HCC1588 CTRP2 6.3404 9.5753 3.7465 3.4022
NCI-H2444 CTRP2 6.3663 9.3032 3.8899 2.8162
NCI-H1573 CTRP2 6.4535 21.9479 -2.2636 23.7355
DMS 454 CTRP2 6.5462 9.9134 3.7186 3.2533
Calu-1 CTRP2 6.6138 16.3571 0.6367 15.0155
NCI-H2342 CTRP2; CTRP1 6.6325 11.6308 2.9738 6.1358
BEN CTRP2 6.6626 7.6537 4.7255 0.082
IA-LM CTRP2 6.6778 7.9977 4.6085 0.2555
VMRC-LCD CTRP2 6.6953 14.1638 1.7766 10.6907
DMS 273 CTRP2 6.704 11.8678 2.8971 6.2676
A-549 CTRP2 6.7371 13.5683 2.0975 9.3806
NCI-H2405 CTRP2 6.7488 11.5839 3.0627 5.5499
MOR/CPR CTRP2 6.7571 7.5885 4.7801 0.0271
SHP-77 CTRP2 6.777 8.2437 4.5572 0.32
NCI-H2126 CTRP2 6.7994 8.4135 4.5022 0.4296
LCLC-103H CTRP2 6.8468 7.94 4.693 0.0873
NCI-H2228 CTRP2 6.849 14.18 1.8792 10.0559
RERF-LC-Ad2 CTRP2 6.8862 8.2144 4.6112 0.1869
KNS-62 CTRP2 6.9352 9.4474 4.1474 1.3336
LC-1/sq-SF CTRP2 6.9548 8.3269 4.5971 0.1907
NCI-H810 CTRP2 6.9982 9.9453 3.9669 1.8716
Calu-6 CTRP2 7.0414 10.1119 3.9177 1.9992
NCI-H69 CTRP2 7.0438 9.8766 4.0208 1.652
NCI-H2029 CTRP2 7.0533 8.7824 4.4689 0.3931
NCI-H2291 CTRP2 7.0655 14.128 2.0567 9.0454
SW1573 CTRP2 7.0973 17.3743 0.4954 14.7037
NCI-H2023 CTRP2; CTRP1 7.1636 14.7232 1.8485 9.7662
NCI-H1651 CTRP2 7.1765 10.0849 4.0009 1.6058
HCC95 CTRP2 7.2334 13.5216 2.462 7.2389
RERF-LC-MS CTRP2 7.2682 12.6265 2.9077 5.4729
NCI-H1184 CTRP2 7.3285 11.0772 3.6517 2.6458
NCI-H1395 CTRP2 7.3956 9.597 4.3031 0.6099
NCI-H1092 CTRP2 7.5421 8.9398 4.5972 0.0827
NCI-H1299 CTRP2 7.552 12.0868 3.3284 3.5697
NCI-H1869 CTRP2 7.5608 19.5589 -0.2375 16.3514
NCI-H2141 CTRP2; CTRP1 7.587 9.5426 4.4164 0.3362
NCI-H1623 CTRP2 7.595 9.1721 4.5367 0.135
NCI-H650 CTRP2 7.6178 15.656 1.6998 9.6004
NCI-H889 CTRP2 7.6647 19.2027 0.0125 15.4007
NCI-H727 CTRP2 7.7471 9.6992 4.4076 0.276
HCC2279 CTRP2 7.9163 20.1087 -1.0005 14.5083
NCI-H1792 CTRP2 7.9331 16.3306 1.5892 9.5686
NCI-H661 CTRP2 8.24 19.8982 0.0827 14.3107
NCI-H2087 CTRP2 8.4917 23.2484 -1.369 18.2107
NCI-H1915 CTRP2; CTRP1 8.8225 16.2818 2.1873 6.3548
NCI-H1373 CTRP2 8.8916 18.8282 1.0345 10.253
RERF-LC-A1 CTRP2 9.7024 18.3586 1.7518 6.8406
NCI-H1944 CTRP2 9.8911 35.6764 -6.444 26.4885
Hs 888.Lu CTRP2 3.9379 9.1017 2.0331 14.9263
⏷ Show the Full List of 153 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.4548 13.9497 -0.7937 25.9298
OVKATE CTRP1 -2.0691 2.4945 -2.1992 81.2777
IGROV-1 CTRP2; CTRP1 1.2852 5.8204 0.71 27.1046
JHOM-1 CTRP2; CTRP1 1.4928 4.7273 1.2524 24.5631
SNU-840 CTRP2; CTRP1 2.4384 9.2985 0.4941 24.5158
RMUG-S CTRP1 2.5108 11.1054 -0.2829 44.3148
RMG-I CTRP2; CTRP1 2.586 11.1755 -0.2439 26.5162
OVCAR-4 CTRP2; CTRP1 2.6595 5.6398 2.2615 17.3899
A2780 CTRP2; CTRP1 2.8446 11.0735 0.053 24.9182
JHOS-4 CTRP1 3.5254 7.321 2.4879 29.3913
EFO-27 CTRP2; CTRP1 3.5948 7.8373 2.3183 14.671
Caov-3 CTRP2; CTRP1 3.8114 8.101 2.4046 13.7992
COV362 CTRP2; CTRP1 4.0508 9.1644 2.1155 14.4142
OVK18 CTRP2; CTRP1 4.1779 7.6385 2.9773 10.6014
TYK-nu CTRP2; CTRP1 4.3233 6.0935 3.8486 6.7052
SNU-119 CTRP2 4.6457 16.5166 -1.0272 23.9702
JHOC-5 CTRP2; CTRP1 4.6579 15.1232 -0.3112 21.8977
COV434 CTRP2; CTRP1 5.5076 16.028 -0.0564 19.3965
OVMANA CTRP1 5.8418 10.1685 3.1236 13.923
COV318 CTRP1 5.9297 10.8331 2.8615 15.5561
TOV-112D CTRP2 5.9314 16.6166 -0.0202 18.4271
OVTOKO CTRP2 5.9405 13.0733 1.7501 12.0509
ONCO-DG-1 CTRP2 6.0047 11.0718 2.7887 7.7663
SNU-8 CTRP2 6.1245 9.9701 3.4132 5.0298
FU-OV-1 CTRP2 6.2209 21.5968 -2.2729 24.1613
Kuramochi CTRP2 6.3702 10.7583 3.2026 5.5223
OVCAR-5 CTRP2 6.5093 16.2735 0.5991 15.3239
COV644 CTRP2; CTRP1 6.7336 13.0307 2.3677 8.3952
EFO-21 CTRP2 6.789 9.525 4.0366 1.8268
ES2 CTRP2 6.8206 7.9005 4.6972 0.087
OV56 CTRP2 6.8657 7.8141 4.742 0.042
MCAS CTRP2 7.0037 14.1454 2.0053 9.3353
TOV-21G CTRP2 7.0568 8.3097 4.6409 0.1098
OVSAHO CTRP2 7.0739 11.7952 3.1732 4.6974
OV-90 CTRP2; CTRP1 7.2641 8.9203 4.5164 0.2621
OVCAR-8 CTRP2; CTRP1 7.3062 9.0933 4.4698 0.3312
JHOS-2 CTRP2 7.3594 13.7651 2.4296 7.1928
OV7 CTRP2; CTRP1 7.421 18.4506 0.215 15.1837
SK-OV-3 CTRP2 7.4399 16.9721 0.9399 12.6233
OAW42 CTRP2; CTRP1 7.5418 13.2261 2.8124 5.5633
OAW28 CTRP2 8.0715 16.726 1.4929 9.729
HEY A8 CTRP2 8.1133 14.603 2.516 5.9173
OC 314 CTRP2 8.2032 17.2726 1.3201 10.1696
DOV13 CTRP2 9.392 20.6857 0.4823 11.4454
OVISE CTRP2 9.5015 18.843 1.4109 8.2216
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 5.7915 17.3199 -0.4824 20.1356
Aska-SS CTRP2 9.51 20.2239 0.7751 10.3418
A-204 CTRP2 0.61 5.7131 0.0071 31.5188
KYM-1 CTRP2 1.1299 4.2279 0.9644 26.6428
G-401 CTRP2 1.3232 4.1524 1.1875 25.254
G-402 CTRP2 1.475 3.7251 1.4141 23.9858
TE 617.T CTRP2 2.4739 4.5323 2.3605 17.5143
GCT CTRP2 2.4793 9.8771 0.2592 25.1322
Rh41 CTRP2 3.0402 11.0581 0.2388 23.7537
RKN CTRP2; CTRP1 4.804 7.1202 3.8088 5.7624
TE 441.T CTRP2 5.5204 9.3153 3.2915 6.4973
BT-16 CTRP2 5.6366 7.9092 4.0705 3.0822
BT-12 CTRP2 5.9907 7.3857 4.5365 0.8594
HT-1080 CTRP2; CTRP1 6.0905 9.9702 3.4008 5.2061
TTC-709 CTRP2 6.4125 15.8558 0.7322 15.0241
Rh18 CTRP2 6.4419 20.0372 -1.3216 21.3706
SW982 CTRP2 6.8091 16.6981 0.6149 14.7647
SK-LMS-1 CTRP2 7.2088 14.7123 1.8737 9.5355
RD CTRP2 7.2661 10.0997 4.0402 1.4116
Tm87-16 CTRP2 8.6356 30.2374 -4.6988 25.326
SK-UT-1 CTRP2 8.7125 16.1306 2.1779 6.4505
Hs 729.T CTRP2 9.5411 18.6195 1.5375 7.746
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 6.1762 7.0355 4.7626 0.1404
P-STS CTRP2 6.8816 8.5799 4.4736 0.4572
SYO-1 CTRP2 7.081 13.1258 2.549 7.1107
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.3298 8.7196 4.5975 0.1121
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 0.1507 12.217 -3.1391 39.7964
MPP 89 CTRP2 1.5801 2.7884 1.5781 23.0863
NCI-H2452 CTRP2 3.193 9.4991 1.1338 20.2043
IST-Mes1 CTRP2 4.8261 10.0278 2.3685 11.6457
NCI-H28 CTRP2 5.7389 10.6762 2.7842 8.2276
ACC-MESO-1 CTRP2 6.4294 13.6041 1.8568 10.8078
NCI-H2052 CTRP2 8.2476 19.5534 0.2548 13.7449
JL-1 CTRP2 11.1295 40.8771 -8.0883 27.2759
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP2; CTRP1 3.8279 7.4735 2.7178 12.4913
DU145 CTRP2 4.2747 9.7584 2.0187 14.2308
VCaP CTRP2 5.3541 7.8157 3.9076 4.2129
LNCaP clone FGC CTRP2 5.5777 10.3432 2.8252 8.337
NCI-H660 CTRP2 6.5618 7.9495 4.5787 0.3645
22Rv1 CTRP2 7.573 10.9537 3.8359 1.8115
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 4.9609 12.3079 1.3428 15.4657
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 0.504 3.4221 0.4197 30.5305
SNU-216 CTRP2 1.1086 5.0458 0.7487 27.4552
NCC-StC-K140 CTRP2 1.6829 5.9635 1.0893 24.4893
AGS CTRP2; CTRP1 2.4758 4.8185 2.3017 17.7951
SNU-1 CTRP2 2.5887 5.8491 2.1084 18.0871
LMSU CTRP2 2.7789 6.8854 1.9063 18.3225
ECC10 CTRP2 3.7292 13.6224 -0.3846 24.0926
KATO III CTRP2 3.985 11.0748 1.1064 18.4346
HGC-27 CTRP2 4.0622 10.7661 1.3287 17.4199
NCI-N87 CTRP2 4.1946 12.2515 0.7103 19.4189
KE-39 CTRP2 4.8065 10.7825 1.9748 13.2903
MKN1 CTRP2 4.8938 11.4703 1.7051 14.191
NUGC-4 CTRP2 5.0667 16.8754 -1.5099 20.9185
HuG1-N CTRP2 5.483 10.6843 2.5811 9.5148
GSU CTRP2 5.5497 6.3913 4.7309 0.6045
GSS CTRP2 5.7673 11.7721 2.2624 10.3135
IM95 CTRP2 5.8417 8.9718 3.699 4.2891
MKN45 CTRP2 6.0698 7.4975 4.5302 0.812
ECC12 CTRP2 6.085 11.8205 2.4797 8.8937
23132/87 CTRP2 6.3003 10.272 3.3887 4.8749
MKN7 CTRP2 6.453 12.1984 2.5625 7.9746
SNU-719 CTRP2 6.4828 8.4716 3.4285 0.4412
SNU-620 CTRP2 6.5472 8.0325 4.5402 0.4629
SNU-5 CTRP2 6.5546 8.0049 4.5542 0.425
Hs 746.T CTRP2 6.8388 11.5258 3.1493 5.0896
Fu97 CTRP2 6.8527 12.5541 2.6687 6.9614
SNU-601 CTRP2 7.0169 12.6559 2.7304 6.4905
SNU-668 CTRP2 7.1075 12.4113 2.9057 5.6869
MKN74 CTRP2; CTRP1 7.289 19.0629 -0.1826 16.6689
NUGC-3 CTRP2 7.8759 9.8699 4.3956 0.2612
SH-10-TC CTRP2 8.418 20.7493 -0.2051 14.9554
SNU-1077 CTRP2 6.7173 11.7844 2.946 6.0548
SNG-M CTRP2; CTRP1 8.1668 16.675 1.5919 9.306
SNU-685 CTRP2 9.9869 19.1141 1.5768 7.1256
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CGTH-W-1 CTRP2 0.1246 4.3339 -0.1487 33.6535
SW579 CTRP2 0.3078 3.0855 0.2495 31.7501
ML-1 [Human leukemia] CTRP2 3.389 13.5652 -0.6636 25.7121
TT2609-C02 CTRP2 5.8969 11.2208 2.6347 8.5749
FTC-238 CTRP2 5.9195 8.742 3.8643 3.5039
CAL-62 CTRP2 6.2918 10.4454 3.2995 5.2455
FTC-133 CTRP2 6.5902 11.7143 2.8933 6.4451
BHT-101 CTRP2 7.0651 13.1249 2.5388 7.1726
8505C CTRP2 8.0915 14.6025 2.5029 5.9914
B-CPAP CTRP2 8.4236 18.6029 0.8325 11.5684
8305C CTRP2 8.5938 19.2848 0.6208 12.0488
TT CTRP2 10.022 24.5758 -0.9493 14.9433
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-8 CTRP2 0.6804 2.3786 0.6749 29.092
BICR 56 CTRP2 1.5727 5.8905 0.9949 25.1577
PE/CA-PJ49 CTRP2 1.643 4.1446 1.5336 23.0336
BICR 6 CTRP2 1.9155 13.0798 -1.8068 32.348
SCC-25 CTRP2 1.9931 7.323 0.9012 24.2551
BICR 18 CTRP2 2.2553 5.0479 1.9996 19.4754
BICR 31 CTRP2 2.3982 5.9214 1.8772 19.5004
SCC-9 CTRP2; CTRP1 2.5164 8.0762 1.1262 22.0553
CAL-33 CTRP2 2.7383 8.5151 1.1467 21.3167
YD-10B CTRP2 2.7602 8.8634 1.0085 21.7694
BICR 16 CTRP2 2.802 13.0855 -0.9697 27.9947
SNU-1076 CTRP2 3.715 12.4766 0.1695 22.3638
HSC-4 CTRP2 4.0295 11.6535 0.8602 19.2441
HSC-2 CTRP2 4.7603 8.3517 3.1485 8.5337
SNU-1214 CTRP2 4.9558 14.5393 0.2229 19.5036
PE/CA-PJ34 (clone C12) CTRP2 5.1175 13.248 1.0034 16.4304
HSC-3 CTRP2 5.7295 7.7288 4.2213 2.3395
SCC-4 CTRP2 6.0588 15.3349 0.7181 15.6941
Detroit 562 CTRP2 6.3802 9.222 3.9361 2.6238
SNU-46 CTRP2 6.499 19.3021 -0.9115 20.1289
BICR 22 CTRP2 6.6286 10.652 3.4253 4.2849
CAL-27 CTRP2 6.6722 13.1988 2.2313 8.9552
SNU-899 CTRP2 7.0845 9.7673 4.0883 1.4019
SNU-1066 CTRP2 7.3548 12.9724 2.8007 5.7731
PE/CA-PJ41 (clone D2) CTRP2 7.4205 13.3315 2.6742 6.1735
PE/CA-PJ15 CTRP2 7.613 13.5916 2.6747 5.9288
BHY CTRP2 7.8244 16.001 1.6738 9.4079
SNU-1041 CTRP2 8.3785 15.2038 2.4011 6.0293
FaDu CTRP2 8.8391 20.8363 0.0433 13.5836
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JMSU-1 CTRP2 -0.4882 2.6712 -0.5483 37.0482
U-BLC1 CTRP2 2.6278 10.8559 -0.0585 25.7698
RT-112 CTRP2 4.6004 10.1428 2.1163 13.1403
UM-UC-1 CTRP2 4.6956 9.1197 2.7093 10.5007
5637 CTRP2 4.7236 20.2919 -3.4909 26.7612
VM-CUB-1 CTRP2 4.8161 11.02 1.8643 13.7143
BC-3C CTRP2 4.9469 13.0368 0.9667 16.9054
CAL-29 CTRP2 5.2916 9.8443 2.8472 8.7607
SW1710 CTRP2 5.6523 13.9288 1.0981 15.0572
BFTC-905 CTRP2 5.7694 7.0988 4.54 1.0629
KMBC-2 CTRP2 5.9604 12.9551 1.8241 11.726
KU-19-19 CTRP2 5.9837 9.142 3.7157 4.011
253J-BV CTRP2 6.0391 10.8856 2.9056 7.2323
SCaBER CTRP2 6.1415 12.3525 2.2594 9.6886
639V CTRP2 6.4162 10.6276 3.2968 5.0794
UM-UC-3 CTRP2 6.7446 13.9957 1.8944 10.1588
HT-1376 CTRP2 6.8013 17.1717 0.3754 15.5961
HT-1197 CTRP2 6.802 8.5243 4.4605 0.5271
RT-4 CTRP2 7.4809 12.7867 2.9662 4.9891
T24 CTRP2 7.6934 15.9997 1.5862 9.9137
TCCSUP CTRP2 8.2457 19.6387 0.2123 13.8854
J82 CTRP2 8.4657 14.3989 2.8169 4.4451
647V CTRP2 8.8092 15.8063 2.3829 5.6153
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 6.0872 21.4141 -2.2885 24.4337

References

1 Developmental toxicity associated with receptor tyrosine kinase Ret inhibition in reproductive toxicity testing. Birth Defects Res A Clin Mol Teratol. 2009 Feb;85(2):130-6.
2 Pharmacophore modeling study based on known spleen tyrosine kinase inhibitors together with virtual screening for identifying novel inhibitors. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1944-9.