Details of the Drug

General Information of Drug (ID: DMGC970)

Drug Name

AG-013

Synonyms

ActoBiotic (oral mucositis), ActoGenix; TFF-producing Lactococci lactis (mucositis), ActoGenix/VIB/University of Ghent; Trefoil factor producing micro-organisms (TopAct, oral, mucositis), ActoGenix

Indication

Disease Entry	ICD 11	Status	REF
Oral mucositis	DA01.11	Phase 2/3	[1]
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Cross-matching ID

TTD ID: D0IJ0F

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Trefoil factor-1 (TFF1)	TTNOJIZ	TFF1_HUMAN	Modulator	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis. Oral Oncol. 2010 Jul;46(7):564-70.