Details of the Drug

General Information of Drug (ID: DMGCQ4E)

Drug Name
Lovastatin acid
Synonyms
Lovastatin acid; Mevinolinic acid; Monacolinic K acid; MSD 803 acid; MSD 803 free acid; UNII-5CLV35Y90C; MK 819; L-154819; L 154819; 5CLV35Y90C; CHEBI:82985; (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID; (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 422.6
Logarithm of the Partition Coefficient (xlogp) 3.5
Rotatable Bond Count (rotbonds) 11
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C24H38O6
IUPAC Name
(3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
Canonical SMILES
CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)O)O)O)C
InChI
InChI=1S/C24H38O6/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28/h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28)/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
InChIKey
QLJODMDSTUBWDW-BXMDZJJMSA-N
Cross-matching ID
PubChem CID
64727
ChEBI ID
CHEBI:82985
CAS Number
75225-51-3
UNII
5CLV35Y90C
DrugBank ID
DB03785
VARIDT ID
DR01679

Molecular Interaction Atlas of This Drug


Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 151 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 2.7065 8.3289 1.9005 31.5045
MEC1 CTRP2 3.4019 5.8077 3.3245 24.4761
JM1 CTRP2 4.8221 8.5304 4.09 17.4205
F-36P CTRP2 0.2399 7.535 -0.752 43.4027
EoL-1 CTRP2 1.107 3.1609 1.1037 39.5715
SU-DHL-1 CTRP2 1.217 2.3869 1.217 38.8256
OPM-2 CTRP2 1.6989 4.8723 1.6282 35.8297
A4/Fukuda CTRP2 1.8798 4.3652 1.856 34.4712
DEL CTRP2 1.9176 2.6655 1.9176 34.1396
P12-Ichikawa CTRP2 1.9209 4.8479 1.8642 34.3038
NCI-H929 CTRP2 1.9564 3.2939 1.9561 33.8811
MOLP-8 CTRP2 2.0158 5.321 1.9116 33.8241
MOLM-16 CTRP2; CTRP1 2.0481 3.7173 2.046 33.4366
GA-10 CTRP2 2.0522 4.704 2.0136 33.3678
SR CTRP2 2.0623 4.239 2.0491 33.2163
NALM-6 CTRP2 2.0738 4.2428 2.0608 33.1384
NB4 CTRP2 2.0884 3.3324 2.0882 32.9982
HD-MY-Z CTRP2 2.0902 4.7371 2.0507 33.1167
THP-1 CTRP2; CTRP1 2.1478 4.7456 2.1113 32.8856
MV4-11 CTRP2 2.1824 3.9697 2.1781 32.3833
JVM-3 CTRP2 2.3426 4.9166 2.3003 31.4391
SU-DHL-4 CTRP2; CTRP1 2.3599 6.8629 1.9829 32.5749
EM-2 CTRP2 2.4243 4.4304 2.4125 30.7905
SET-2 CTRP2 2.447 5.3566 2.3659 30.871
SUP-HD1 CTRP2 2.5454 4.5225 2.5331 29.9824
ST486 CTRP2 2.6306 4.6351 2.6159 29.4208
KE-37 CTRP2 2.6417 5.4832 2.5571 29.5823
KMS-11 CTRP2; CTRP1 2.6426 4.6013 2.6302 29.5048
L-540 CTRP2 2.6707 4.6283 2.6573 29.1482
RPMI-8402 CTRP2 2.684 5.846 2.5492 29.4696
Ki-JK CTRP2 2.691 4.4378 2.6842 28.9905
Reh CTRP2 2.7176 5.0159 2.684 28.9028
KMS-34 CTRP2 2.7606 5.7851 2.6414 28.9053
Karpas-299 CTRP2 2.8525 5.5221 2.7764 28.1445
JVM-2 CTRP2 2.9483 7.1724 2.5343 28.6608
Ci-1 CTRP2 2.9693 5.0352 2.9444 27.1902
MOLT-16 CTRP2 2.9821 5.316 2.9357 27.1772
HuT 78 CTRP2 3.018 5.0744 2.9925 26.8663
EB1 CTRP2 3.0623 6.3807 2.8574 27.1855
OCI-AML-5 CTRP2 3.0879 4.2606 3.0837 21.1715
HEL 92.1.7 CTRP2 3.1156 6.4248 2.9058 26.847
SKM-1 CTRP2; CTRP1 3.1288 5.1676 3.1023 26.3088
WSU-DLCL2 CTRP2; CTRP1 3.148 4.9037 3.1361 26.1311
SIG-M5 CTRP2 3.1811 4.1239 3.181 25.6904
MOLM-13 CTRP2 3.1832 6.9007 2.8651 26.7734
HuNS1 CTRP2 3.1851 4.4044 3.184 25.6667
RPMI-6666 CTRP2 3.195 4.2344 3.1947 25.5977
Pfeiffer CTRP2 3.2772 6.9642 2.9509 26.1768
Jurkat CTRP2 3.307 7.9628 2.6768 27.0408
RCH-ACV CTRP2 3.3141 7.6397 2.7915 26.62
Daudi CTRP2 3.3752 5.9014 3.2826 24.707
DoHH2 CTRP2 3.3895 13.3392 0.491 33.1239
OCI-AML-3 CTRP2; CTRP1 3.4004 5.3164 3.3745 24.4946
Mino CTRP2 3.4607 6.2148 3.3224 24.2943
OCI-Ly3 CTRP2 3.5117 7.8003 2.9536 25.4408
MOLM-6 CTRP2 3.5253 6.4718 3.341 24.0235
KMS-27 CTRP2 3.54 6.2256 3.406 23.7491
RPMI-8226 CTRP2; CTRP1 3.5778 6.6549 3.362 23.9692
SUP-T11 CTRP2 3.6271 6.3134 3.4837 23.2
M-07e CTRP2 3.6364 5.7655 3.4871 17.7858
HT CTRP2; CTRP1 3.7002 5.6454 3.6596 22.3555
K-562 CTRP2 3.722 6.4347 3.5624 22.6225
HEL CTRP2 3.7256 6.074 3.632 22.368
PF-382 CTRP2 3.7274 7.0305 3.4243 23.0963
BL-70 CTRP2; CTRP1 3.7426 5.4346 3.7211 22.0069
Namalwa CTRP2 3.7566 7.4306 3.3391 23.3136
Mono-Mac-1 CTRP2 3.814 8.4858 3.0353 24.2413
KM-H2 CTRP2 3.8148 6.6397 3.6184 22.1327
EHEB CTRP2 3.8333 7.5672 3.3793 22.9362
SU-DHL-5 CTRP1 3.8398 6.2668 3.726 46.3142
CA46 CTRP2 3.8429 8.2295 3.1615 23.6989
SEM CTRP2 3.8631 5.335 3.8512 21.1687
Hs 611.T CTRP2 3.9521 7.3816 3.5671 21.8951
U-937 CTRP2; CTRP1 3.9551 6.1079 3.8759 20.9767
AML-193 CTRP2 3.9576 5.9051 3.9035 20.6802
JJN-3 CTRP2 4.0189 6.7371 3.6123 16.0674
KE-97 CTRP2; CTRP1 4.0268 6.4561 3.8886 20.5105
OCI-AML-2 CTRP2 4.0612 5.6714 4.0359 19.8889
KMS-18 CTRP2 4.2043 7.1227 3.9189 19.8514
RL CTRP2 4.2056 6.5991 4.0527 19.3669
GDM-1 CTRP2; CTRP1 4.2219 7.9804 3.6699 20.9067
SU-DHL-8 CTRP2 4.2344 7.0751 3.9652 19.5915
KMS-20 CTRP2 4.2895 6.821 3.8725 14.1838
TALL-1 [Human adult T-ALL] CTRP2 4.3377 8.2452 3.6868 20.3172
CMK CTRP2 4.3729 6.0015 4.3325 17.8562
PL21 CTRP2; CTRP1 4.3821 7.652 3.9565 19.3764
NCO2 CTRP2 4.428 10.6202 2.7769 23.4358
SU-DHL-10 CTRP2 4.4616 5.3197 4.4605 17.1295
L-428 CTRP2 4.4819 7.73 3.7019 14.3334
KMS-28BM CTRP2 4.5024 10.7018 2.8148 23.0991
NU-DUL-1 CTRP2; CTRP1 4.5368 6.7003 4.3955 17.3142
NU-DHL-1 CTRP2 4.5487 6.4021 4.3021 11.6497
HL-60 CTRP2 4.5827 7.6166 4.1768 17.772
Peer CTRP2 4.5892 7.8165 4.1145 17.9857
OCI-M1 CTRP2 4.602 6.7609 4.4474 16.7243
KMS-26 CTRP2 4.6044 6.1303 4.563 16.3115
HDLM-2 CTRP2 4.682 10.5488 3.0648 21.7084
BV-173 CTRP2 4.6924 6.9099 4.5094 16.2219
MOTN-1 CTRP2 4.7003 8.0881 4.1342 17.5926
L-363 CTRP2 4.7721 6.8794 4.6041 15.6356
DB CTRP2 4.7863 7.9827 4.2659 16.8478
SUP-T1 CTRP2 4.7972 10.0727 3.3971 20.1567
Karpas-422 CTRP2 4.8759 8.4587 4.1758 16.9413
P31/FUJ CTRP2 4.9188 7.9117 4.4345 15.8303
MC116 CTRP2; CTRP1 5.0581 6.8697 4.9184 13.6234
KMS-12-BM CTRP2 5.1169 6.3812 5.0764 12.8811
JeKo-1 CTRP2 5.1822 8.3427 4.5459 14.6668
MM1.S CTRP2 5.3134 10.5397 3.6946 17.6855
RS4;11 CTRP2 5.3272 7.6096 4.9843 13.4623
Kasumi-1 CTRP2 5.3697 8.4001 4.7185 13.4843
HH [Human lymphoma] CTRP2 5.3792 11.1749 3.4566 18.4513
HPB-ALL CTRP2 5.3889 6.735 5.3092 11.1996
Ku812 CTRP2; CTRP1 5.3919 8.4472 4.7218 13.4116
KMS-21-BM CTRP2 5.3942 8.6001 4.6589 13.6531
LP-1 CTRP2; CTRP1 5.405 9.4263 4.3189 15.1782
Mono-Mac-6 CTRP2 5.4051 12.787 2.7019 21.2063
OCI-Ly19 CTRP2 5.4078 9.2853 4.3694 14.7677
697 CTRP2 5.4119 8.1397 4.8706 12.7763
ME1 CTRP2 5.5355 9.4429 4.4254 14.22
Raji CTRP2 5.5744 8.7274 4.7886 12.6657
KHM-1B CTRP2 5.6258 10.1574 4.1796 14.9875
MHH-CALL-4 CTRP2 5.6286 7.8339 5.2224 10.8161
JURL-MK1 CTRP2 5.6607 7.5966 5.3477 10.2457
SK-MM-2 CTRP2 5.7447 7.6291 5.4256 10.3934
KCL-22 CTRP2 5.7963 9.3563 4.7239 12.3663
KO52 CTRP2 5.8858 8.479 5.2162 10.1536
A3/Kawakami CTRP2 5.9997 7.3838 5.7902 7.598
Ri-1 CTRP2 6.0006 9.3461 4.9283 11.0365
MOLP-2 CTRP2 6.0043 12.058 3.6129 16.3719
MOLT-13 CTRP2 6.0049 10.3005 4.4737 12.8925
OCI-Ly10 CTRP2; CTRP1 6.0257 10.3962 4.4666 13.0756
CML-T1 CTRP2 6.0748 8.9603 5.1831 9.8156
Granta-519 CTRP2 6.0844 8.8992 5.2212 9.6365
MOLT-3 CTRP2 6.1387 6.9119 6.0858 6.0933
SU-DHL-6 CTRP2 6.1692 9.3483 5.0895 9.9741
Kasumi-2 CTRP2 6.1999 12.1694 3.1105 12.8205
MHH-CALL-3 CTRP2 6.2586 11.0534 4.3397 12.8702
SUP-B15 CTRP2 6.3072 9.711 5.0438 9.8452
NOMO-1 CTRP2; CTRP1 6.4271 9.5329 5.2626 8.8771
AMO1 CTRP2; CTRP1 6.4711 7.876 6.0961 5.3532
TF-1 CTRP2 6.5146 8.3822 5.8837 5.8883
SUP-M2 CTRP2 6.6184 7.0727 6.5669 2.8846
U266B1 CTRP2 6.6279 12.4729 3.3025 11.1414
LAMA-84 CTRP2 6.7951 20.294 0.1962 25.6681
EJM CTRP2; CTRP1 6.8982 8.9618 5.9704 4.9018
Toledo CTRP2 6.9121 8.0211 6.4283 2.7289
KYO-1 CTRP2 7.0156 8.902 6.0769 4.0024
P3HR-1 CTRP2; CTRP1 7.0275 10.4651 5.3053 7.2348
Karpas-620 CTRP2 7.9759 11.8897 5.3303 5.4888
REC-1 CTRP2 8.6178 15.4974 4.0297 9.7459
KMM-1 CTRP2 8.6948 14.2388 4.6949 6.9911
⏷ Show the Full List of 151 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 2.8827 6.2585 2.6879 28.3482
TE8 CTRP2 4.3495 5.9816 4.3099 19.2762
KYSE-150 CTRP2 0.4681 3.5167 0.4191 40.057
KYSE-30 CTRP2 2.6498 5.5263 2.4673 24.9641
TE-9 CTRP2 2.7539 5.076 2.7173 28.6701
TE-11 CTRP2 3.1265 5.9127 3.0141 26.4376
TE-6 CTRP2 3.472 6.8343 3.1975 24.6973
KYSE-180 CTRP2 3.987 6.8792 3.7477 21.1355
KYSE-520 CTRP2 4.0445 9.03 3.0673 23.4549
TE-5 CTRP2 4.7633 7.1879 4.5099 16.0043
EC-GI-10 CTRP2 4.7668 9.2803 3.717 19.0109
KYSE-450 CTRP2; CTRP1 4.9401 7.4687 4.6141 15.0931
KYSE-140 CTRP2; CTRP1 4.9881 8.1743 4.4081 15.7355
OE21 CTRP2 5.0567 8.1449 4.4925 15.2199
TE-4 CTRP2 5.1479 7.6846 4.7641 14.9046
OE33 CTRP2 5.4388 9.6183 4.2483 15.1734
KYSE-70 CTRP2 5.4792 6.9199 5.0777 5.6974
TE-10 CTRP2 5.6301 10.6501 3.9488 15.9047
KYSE-410 CTRP2; CTRP1 5.7702 8.8491 4.9323 11.5882
TE-14 CTRP2 6.2814 18.5579 -0.016 23.8497
TE-1 CTRP2 6.7427 11.675 4.4591 11.3485
KYSE-510 CTRP2 7.9624 12.9079 4.0492 5.7073
OE19 CTRP2 8.1127 11.7426 5.4975 4.6028
COLO 680N CTRP2 9.0697 11.1057 6.3306 0.6453
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 5.4333 8.2191 4.8605 12.7572
SW1990 CTRP2 1.9093 12.3653 -0.5679 39.7546
Panc 08.13 CTRP2 2.4913 9.0954 1.0538 37.3787
KP-3 CTRP2; CTRP1 2.7075 8.6852 1.7737 31.8851
MIA PaCa-2 CTRP2 2.7403 3.7117 2.7403 28.6377
Panc 03.27 CTRP2; CTRP1 2.8063 5.564 2.7219 28.4816
PSN1 CTRP2 2.8569 4.5566 2.8498 27.8817
Hs 766T CTRP2 3.1254 9.6462 1.4681 27.1292
KP-4 CTRP2 3.4696 7.4306 3.0265 25.3113
HuP-T4 CTRP2; CTRP1 3.5669 6.0166 3.4707 23.4378
KP-2 CTRP2 4.3066 6.0228 4.2597 18.3218
BxPC-3 CTRP2 4.3995 8.634 3.6017 20.462
PK-59 CTRP2 4.6913 9.7571 3.4308 20.3095
YAPC CTRP2 4.7231 8.9347 3.819 18.736
DAN-G CTRP2 4.9542 7.6266 4.5756 15.1953
SU.86.86 CTRP2 5.221 10.6263 3.5635 18.428
Panc 04.03 CTRP2 5.4114 9.1667 4.4266 14.5304
L3.3 CTRP2 5.5352 8.1628 4.9907 11.972
AsPC-1 CTRP2 5.7304 13.4466 2.6789 20.5193
SUIT-2 CTRP2; CTRP1 5.842 7.7925 5.465 9.2874
PK-45H CTRP2 5.8675 10.0927 4.4435 13.3375
HuP-T3 CTRP2 6.0999 12.9999 3.2339 17.6279
HPAF-II CTRP2 6.388 11.4324 4.2687 12.8799
Capan-2 CTRP2; CTRP1 6.3894 10.9082 3.8937 9.0041
TCC-Pan2 CTRP2 6.6925 11.9062 3.6345 9.5727
Capan-1 CTRP2 6.8978 9.3795 5.7385 5.6638
Panc 02.03 CTRP2 6.9286 10.2391 5.3352 7.3023
SNU-410 CTRP2 6.9593 10.9131 5.0242 8.5512
SNU-213 CTRP2 6.9655 11.2053 4.8833 9.1311
PaTu 8988t CTRP2 7.109 9.7536 5.7282 5.2952
PaTu 8988s CTRP2 7.1095 9.3232 5.9437 4.3855
CFPAC-1 CTRP2 7.4867 11.107 5.353 6.1932
Panc 05.04 CTRP2 7.6403 12.5595 4.7504 8.4399
Panc 10.05 CTRP2 8.4471 13.277 4.988 6.1761
HPAC CTRP2 8.4836 10.6547 6.2308 1.3568
PaTu 8902 CTRP2; CTRP1 8.7522 14.1304 4.7861 6.5459
QGP-1 CTRP2; CTRP1 10.294 18.6943 3.6357 8.8385
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.6929 17.9244 1.2944 22.9132
LOX-IMVI CTRP2 1.2389 4.4899 1.1807 38.8552
Mel JuSo CTRP2 1.666 2.5438 1.666 35.8227
MDA-MB-435S CTRP2 1.8427 5.4627 1.7065 35.0764
CJM [Human melanoma] CTRP2 1.8617 3.9126 1.8543 34.5382
HMCB CTRP2 1.9096 3.5601 1.9079 34.1991
MeWo CTRP2 2.3223 5.0699 2.2653 31.6236
WM266-4 CTRP2 2.7314 5.4829 2.6526 28.9631
A101D CTRP2 2.8356 3.5395 2.8356 28.0002
Hs 294T CTRP2 2.9978 3.8134 2.9977 26.9159
UACC-62 CTRP2 3.0091 6.0408 2.8663 27.3267
IGR-39 CTRP2 3.2314 6.0494 3.1044 25.787
RPMI-7951 CTRP2 3.2431 4.8935 3.2334 25.3075
WM115 CTRP2 3.3862 5.9956 3.2799 24.6808
WM983B CTRP2 3.4246 9.8506 2.0785 28.6769
SK-MEL-2 CTRP2 3.4951 4.4304 3.4949 23.5904
G-361 CTRP2; CTRP1 3.5014 5.1826 3.4862 23.5987
Hs 944.T CTRP2; CTRP1 3.6661 5.5697 3.6308 22.5654
COLO 792 CTRP2 3.6854 6.9176 3.4087 23.2824
IGR-1 CTRP2 3.6866 7.5412 3.2282 23.9262
Hs 895.T CTRP2 3.8247 12.6562 1.2392 29.9924
RVH-421 CTRP2 4.1526 6.7881 3.9512 19.8937
SK-MEL-31 CTRP2 4.4656 10.6677 2.7933 23.2756
K029AX CTRP2 4.4917 9.545 3.3185 21.2735
HT-144 CTRP2 4.5217 8.0104 3.9716 18.7179
SK-MEL-5 CTRP2; CTRP1 4.8971 6.5379 4.8187 14.6906
WM88 CTRP2 4.9516 7.1939 4.7134 14.6916
SK-MEL-24 CTRP2 4.9818 7.9844 4.4747 15.4984
Hs 852.T CTRP2; CTRP1 5.0129 7.7818 4.5835 14.996
A2058 CTRP2 5.1931 7.773 4.7804 13.7345
Malme-3M CTRP2 5.2115 9.2252 4.1974 15.9571
A-375 CTRP2; CTRP1 5.2294 7.4774 4.9341 13.2613
UACC-257 CTRP2 5.8008 9.3228 4.7441 12.2732
IPC-298 CTRP2 5.9751 7.7039 5.6413 8.2376
SK-MEL-3 CTRP2 6.2826 11.0348 4.3706 12.6898
Hs 936.T CTRP2; CTRP1 6.3938 9.9811 4.9913 9.8694
COLO 829 CTRP2 6.4989 14.958 2.6104 19.0567
WT2-iPS CTRP2 6.708 7.1963 6.62 2.4258
IGR-37 CTRP2 6.7318 9.5132 4.8441 4.1491
WM793 CTRP2 6.8386 10.7045 5.026 8.7839
SK-MEL-28 CTRP2; CTRP1 6.9177 7.3831 6.768 1.5274
SK-MEL-30 CTRP2 6.9623 7.8619 6.5515 2.1064
SK-MEL-1 CTRP2; CTRP1 7.1788 12.9137 4.2308 11.6209
Hs 940.T CTRP2 7.5116 16.4182 2.7257 16.61
COLO 741 CTRP2 7.5628 9.3154 6.289 2.1907
Mel Ho CTRP2 7.7419 10.7464 5.7206 4.2458
COLO 800 CTRP2 8.2619 14.6474 4.1871 9.6921
WM1799 CTRP2 8.5617 12.0244 5.6582 3.3678
Hs 839.T CTRP2 8.9571 21.8112 1.172 19.0589
Hs 688(A).T CTRP2 9.8011 18.4323 3.4341 10.2417
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 5.2124 9.6694 3.9983 16.7426
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 CTRP2 1.1914 4.1463 1.1566 39.1036
SK-N-SH CTRP2 1.9995 4.4592 1.9746 33.6746
KP-N-SI9s CTRP2 2.2718 4.1264 2.2658 31.791
SK-N-BE(2) CTRP2 4.1631 8.0106 3.5855 21.2005
NB1 CTRP2 4.1925 6.5313 4.0529 19.4077
SK-N-FI CTRP2 4.768 10.0713 3.3683 20.343
SK-N-AS CTRP2 5.1488 7.292 4.8981 13.4222
Kelly CTRP2 5.5803 12.4488 3.0302 19.5886
MHH-NB-11 CTRP2 5.7582 7.0824 5.6259 8.9212
KP-N-YN CTRP2 6.5519 7.6448 6.266 4.2377
SK-N-DZ CTRP2 6.8834 7.6122 6.6049 2.0507
NH-6 CTRP2 6.8977 10.6727 5.0923 8.3868
IMR-32 CTRP2 6.9818 26.7062 -2.8534 31.3102
CHP-126 CTRP2 7.5715 10.7644 5.587 5.0722
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 0.0836 3.1167 0.0656 46.438
HuH-28 CTRP2 1.6785 7.0801 1.1746 37.1834
SNU-869 CTRP2 4.0233 7.6403 3.562 21.7001
SNU-478 CTRP2 5.0625 9.4348 3.9524 17.3111
SNU-308 CTRP2 5.1198 8.7933 4.2918 15.8274
HuCC-T1 CTRP2 6.065 10.1804 4.5885 12.2817
SNU-245 CTRP2 6.1166 10.61 4.4272 12.8275
SNU-1196 CTRP2 6.9254 10.2351 5.3345 7.3118
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MG-63 CTRP2 1.2015 4.4505 1.1449 39.0997
SaOS-2 CTRP2 1.8485 4.2422 1.8298 34.6636
A-673 CTRP2 2.5584 4.1447 2.5554 29.8643
CAL-78 CTRP2 2.6928 8.1868 1.9349 31.4438
TC71 CTRP2 3.0612 4.1276 3.0609 26.4926
SK-ES-1 CTRP2 3.0903 4.9415 3.0746 26.3499
HOS CTRP2 3.4686 4.3715 3.4684 23.7677
U2OS CTRP2 3.5989 5.8599 3.5275 23.1385
MHH-ES-1 CTRP2 3.7953 5.4618 3.774 21.6537
SJSA-1 CTRP2 4.4919 7.6186 4.0777 19.6996
G-292 clone A141B1 CTRP2 4.5862 8.6661 3.3827 15.4109
SK-N-MC CTRP2 4.9838 7.1717 4.7551 14.4424
Hs 888.T CTRP2 5.4108 10.9695 3.5853 17.8739
SW1353 CTRP2 6.1468 9.3991 5.0437 10.2157
Hs 822.T CTRP2 6.7267 14.6441 2.9623 17.3041
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 72 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-157 CTRP2 -0.2336 12.8036 -3.362 47.317
MDA-MB-231 CTRP2 1.9471 5.7287 1.7755 34.4937
SK-BR-3 CTRP2 3.5683 6.1827 3.3031 18.7198
DU4475 CTRP2 3.883 6.1519 3.7887 21.3181
HCC1806 CTRP2 3.8967 6.2425 3.7881 21.2762
BT-549 CTRP2 3.9836 7.4357 3.5846 21.7362
CAL-51 CTRP2 4.1013 6.7217 3.9113 20.1957
HCC1954 CTRP2 4.1603 6.8179 3.9523 19.8659
HMC-1-8 CTRP2 4.5118 7.4355 4.1595 18.0451
CAL-85-1 CTRP2 4.5829 9.2803 3.5266 20.2378
MDA-MB-415 CTRP2 4.6691 9.9197 3.3359 20.7285
MDA-MB-468 CTRP2 4.7306 7.0791 4.5055 16.1191
JIMT-1 CTRP2 4.8792 7.1242 4.6549 15.1242
Hs 578Bst CTRP2 5.3369 15.8066 1.1572 26.3102
BT-20 CTRP2 5.3862 9.0876 4.4365 14.5556
AU565 CTRP2 5.591 9.2645 4.5628 13.5281
Hs 578T CTRP2 5.6295 7.9336 5.1836 10.9634
HDQ-P1 CTRP2 5.7111 10.6027 4.049 15.3092
CAL-120 CTRP2 5.7602 7.6024 5.4523 9.5649
CAL-148 CTRP2 5.8381 7.9912 5.3792 9.633
HCC1569 CTRP2 6.0301 8.9541 5.1422 10.0915
HCC1419 CTRP2 6.1676 10.818 4.3724 12.9378
ZR-75-30 CTRP2 6.3784 7.5905 6.1115 5.3062
MDA-MB-453 CTRP2 6.444 10.9181 4.5738 11.4984
HCC1395 CTRP2 6.5888 12.2008 4.0635 13.2934
HCC38 CTRP2 6.8641 11.8315 4.4847 10.9968
MCF-7 CTRP2; CTRP1 6.9221 11.9478 4.4995 11.0174
HCC1143 CTRP2 6.9677 9.9431 5.5162 6.4617
ZR-75-1 CTRP2 7.0742 12.3274 3.7144 8.5357
HCC1428 CTRP2 7.1803 11.3057 5.0108 8.1827
BT-474 CTRP2 7.5006 9.581 5.2915 1.3184
UACC-812 CTRP2 7.5699 10.8832 5.527 5.3247
KPL-1 CTRP2 7.6842 8.6924 6.6531 0.6511
T-47D CTRP2 7.9145 13.9857 3.5035 8.0613
HCC1937 CTRP2 7.9302 15.1556 3.6853 12.241
MDA-MB-361 CTRP2 7.9376 9.7503 6.3246 2.3592
HCC202 CTRP2 8.1641 11.6728 5.566 4.2528
CAMA-1 CTRP2 8.2936 11.9395 5.5255 4.2355
BT 416 CTRP2 1.748 13.7146 -1.3288 41.3052
BT 248 CTRP2 6.179 7.0901 6.0827 5.981
BT 428 CTRP2 6.3015 7.2506 6.1634 5.3196
BT 498 CTRP2 6.4903 15.7655 2.1998 20.4917
BT 245 CTRP2 6.4937 11.9062 4.127 13.2347
BT 172 CTRP2 6.5875 9.4914 5.4091 7.6994
BT 482 CTRP2 6.5997 8.0046 6.1462 4.6066
BT147 CTRP2 6.601 14.4659 2.9439 17.6341
BT 444 CTRP2 6.6013 7.4758 6.3915 3.6091
BT 286 CTRP2 6.6182 15.1875 2.5983 18.8473
BT 139 CTRP2 6.6957 9.4617 4.8434 4.2117
BT 422 CTRP2 7.0519 9.6044 5.7559 5.2869
BT 131 CTRP2 7.1165 10.1004 5.5611 5.9856
BT 271 CTRP2 7.2122 22.3177 -0.4677 26.4191
BT 216 CTRP2 7.4709 12.6931 4.5516 9.5641
BT 228 CTRP2 7.4922 12.1303 4.1071 6.1512
BT 231 CTRP2 7.6234 20.0047 0.3326 20.2204
BT 340 CTRP2 7.7082 12.0926 5.0337 7.1474
BT 320 CTRP2 7.7852 9.175 6.4957 1.108
BT 145 CTRP2 7.8558 17.5446 2.4387 16.9747
BT 159 CTRP2 8.0227 12.0495 4.4865 3.8337
BT 232 CTRP2 8.1106 14.2972 4.2473 9.6997
BT164 CTRP2 8.2114 19.5257 1.7319 18.6566
BT 440 CTRP2 8.2765 12.3794 5.3033 5.1517
BT 239 CTRP2 8.3663 15.3958 3.1335 8.8963
BT 333 CTRP2 8.7227 13.8169 4.9164 6.0698
BT 330 CTRP2 8.8931 19.0055 2.5094 14.9252
BT 328 CTRP2 9.1208 13.5419 5.301 4.0601
BT 504 CTRP2 9.1746 19.961 2.2473 15.3508
BT 224 CTRP2 10.0881 18.4015 3.6401 9.0947
BT 359 CTRP2 10.4754 24.9327 0.7564 17.8482
BT 187 CTRP2 11.0757 24.1586 0.7587 13.511
BT 179 CTRP2 11.2347 22.8422 2.2874 12.2135
BT 112 CTRP2 11.5662 25.2797 1.3465 14.6478
⏷ Show the Full List of 72 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.3998 5.577 3.3498 24.3963
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF268 CTRP2 0.7632 4.5738 0.6717 42.0934
SNU-1105 CTRP2 1.5728 3.8521 1.562 36.4814
KG-1-C CTRP2 1.6229 8.7054 0.3001 35.6934
GB-1 CTRP2 1.6561 4.5923 1.6088 36.0416
YKG-1 CTRP2 1.7793 4.7877 1.721 35.2541
SNU-466 CTRP2 1.8456 7.1659 1.333 36.1429
42-MG-BA CTRP2 2.0956 5.0499 1.9601 28.7484
U-251MG CTRP2 2.3028 5.8711 2.1342 32.1221
SF126 CTRP2 2.3851 3.6637 2.3847 31.0143
DK-MG CTRP2 2.4399 4.52 2.4251 30.6962
SF295 CTRP2; CTRP1 2.4599 5.3573 2.3795 30.7825
Daoy CTRP2 2.5107 4.4503 2.5001 30.2089
ONS-76 CTRP2 2.8696 4.8318 2.8527 27.8295
YH-13 CTRP2 2.8858 4.2007 2.8846 27.6687
A-172 CTRP2 2.9262 6.4623 2.6916 28.1947
SNU-626 CTRP2 2.9672 6.7774 2.6613 28.1665
LN-18 CTRP2 3.0283 5.4085 2.9754 26.8903
SNU-201 CTRP2 3.1628 6.8754 2.8496 26.892
M059K CTRP2 3.2219 4.5356 3.2198 25.4239
D283 Med CTRP2 3.5837 6.0121 3.4894 23.3189
Hs 683 CTRP2 3.5845 6.0963 3.4768 23.3601
KNS-42 CTRP2 3.5845 5.7805 3.5224 23.2026
SF539 CTRP2 3.6403 7.7339 3.1152 24.4728
KNS-60 CTRP2 3.6859 6.0618 3.5913 22.6367
SNU-489 CTRP2 3.7545 5.7736 3.7035 22.0277
KALS-1 CTRP2 3.7602 7.1389 3.4298 22.9759
U-118MG CTRP2 3.9383 6.5823 3.7658 21.2228
GMS-10 CTRP2 4.082 9.0316 3.1062 23.2057
LN-229 CTRP2; CTRP1 4.213 6.9903 3.9716 19.8293
8-MG-BA CTRP2 4.3237 6.6581 4.1681 18.5876
KNS-81 CTRP2 4.462 9.8075 3.1736 23.3829
T98G CTRP2 4.487 6.3589 4.4043 17.2395
SNB-75 CTRP2 4.9417 9.351 3.4015 14.4105
CCF-STTG1 CTRP2 5.0945 8.2139 4.5054 15.0651
SW1783 CTRP2 5.3195 11.1794 3.3971 18.8273
SNU-738 CTRP2 5.3518 8.079 4.8315 13.0931
Becker CTRP2 5.3672 10.9934 3.5318 18.189
SW1088 CTRP2 5.4071 9.1221 4.4424 14.4784
GaMG CTRP2; CTRP1 5.5919 7.2208 5.4029 10.2389
NMC-G1 CTRP2 5.62 8.9508 4.7349 12.7634
CAS-1 CTRP2 5.6906 10.257 4.1949 14.7695
TM-31 CTRP2 6.1803 9.5863 4.9852 10.3785
GOS-3 CTRP2 6.3727 11.3739 4.284 12.8499
U-87MG ATCC CTRP2 6.4826 11.1333 4.5014 11.716
DBTRG-05MG CTRP2 7.3934 13.4851 4.0948 11.5791
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 CTRP2 1.8903 3.7316 1.8867 34.3345
ESS-1 CTRP2 2.3202 4.3583 2.3086 31.4861
JHUEM-2 CTRP2; CTRP1 2.3982 5.6421 2.2776 31.4955
HEC-1-A CTRP2 2.5481 4.7173 2.4925 25.2205
JHUEM-3 CTRP2 2.8621 7.0642 2.4706 29.1541
AN3-CA CTRP2 3.144 5.8501 3.0427 26.2826
MFE-296 CTRP2 3.4287 6.311 3.1128 19.914
HEC-1-B CTRP2 3.8068 7.3406 3.4214 22.8637
HEC-50B CTRP2 3.8193 9.7187 2.5463 25.954
JHUEM-7 CTRP2 4.2557 6.5225 4.1233 18.9599
HEC-265 CTRP2; CTRP1 4.3108 5.5166 4.303 18.1607
KLE CTRP2; CTRP1 4.3658 7.7524 3.8954 19.4558
HEC-251 CTRP2; CTRP1 4.4548 7.2623 4.1513 18.2457
MFE-319 CTRP2; CTRP1 4.7104 6.1673 4.6711 15.5954
HEC-6 CTRP2; CTRP1 5.0859 6.5645 5.0141 13.1974
HEC-151 CTRP2; CTRP1 5.2273 7.3079 4.9869 13.0722
JHUEM-1 CTRP2 6.1337 8.3105 5.5428 8.2097
EFE-184 CTRP2 6.5838 10.3146 4.9979 9.4297
HEC-59 CTRP2; CTRP1 7.2129 9.9094 5.7344 5.0768
HEC-108 CTRP2; CTRP1 7.4515 10.7844 5.4859 5.6977
EN CTRP2 7.6937 12.0276 5.0548 7.084
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 4.8692 5.9317 4.8581 14.4372
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 1.0055 39.3186 -14.3785 53.5742
ACHN CTRP2 1.1449 3.7044 1.13 39.3546
UO-31 CTRP2 1.7469 4.6173 1.653 31.0885
TUHR10TKB CTRP2 2.0671 5.2713 1.9726 33.4508
786-O CTRP2 2.9242 5.1818 2.8869 27.5336
VMRC-RCW CTRP2; CTRP1 3.6993 6.3313 3.5584 22.7085
TUHR4TKB CTRP2 4.3512 8.9001 3.4433 21.1936
Caki-2 CTRP2 4.3941 5.9859 4.3565 17.7048
BFTC-909 CTRP2 4.5996 7.4534 4.2492 17.4528
769-P CTRP2 4.7296 7.1889 4.4728 16.2414
Caki-1 CTRP2 5.1208 7.9858 4.6227 14.5408
CAL-54 CTRP2 5.2352 10.0795 3.8326 17.3384
VMRC-RCZ CTRP2 5.6606 8.1361 5.133 11.0762
KMRC-1 CTRP2 5.94 8.9665 5.0476 10.6977
KMRC-20 CTRP2 6.494 10.686 4.7335 10.7265
OS-RC-2 CTRP2 6.8899 13.1464 3.8492 13.5438
RCC10RGB CTRP2; CTRP1 6.9892 10.2738 5.393 7.1472
SNU-1272 CTRP2 7.1779 12.788 4.2682 11.2777
KMRC-2 CTRP2 7.4661 10.1528 5.8098 4.3184
KMRC-3 CTRP2 8.3138 12.2668 4.5591 3.2091
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCT 15 CTRP2 1.558 4.8463 1.4823 36.7833
GP2d CTRP2 1.5581 7.1455 1.025 38.0175
T84 CTRP2 2.0518 5.0592 1.9112 29.0799
SW1417 CTRP2 2.6553 14.3491 -0.7054 37.6248
SK-CO-1 CTRP2 2.7479 6.4753 2.4948 29.4439
NCI-H747 CTRP2 3.0341 5.2978 2.9921 26.8146
SNU-1033 CTRP2 3.0793 25.2452 -6.1267 40.5241
NCI-H716 CTRP2 3.1063 5.0748 3.084 26.2651
CL-11 CTRP2 3.2376 8.753 2.3174 28.4746
SW403 CTRP1 3.4754 5.8779 3.0542 25.8065
LS180 CTRP2; CTRP1 3.5509 5.6524 3.5032 23.5646
HCC-56 CTRP2 3.7205 4.3074 3.7205 22.0821
COLO 678 CTRP2; CTRP1 3.7387 7.9366 3.1628 24.1876
COLO 320 CTRP2; CTRP1 3.9674 9.2754 2.899 24.4631
SNU-C2A CTRP2; CTRP1 4.4424 7.7768 3.9698 18.9545
HT115 CTRP2; CTRP1 4.7075 6.424 4.634 15.938
LS123 CTRP2; CTRP1 4.776 10.0458 3.4038 20.3736
SW620 CTRP2; CTRP1 4.842 8.5722 4.1069 17.4994
SW480 CTRP1 4.9245 13.1604 2.0873 41.5758
SW48 CTRP2 4.9701 7.5723 4.6116 15.0144
MDST8 CTRP2; CTRP1 5.0114 6.7362 4.9035 14.0318
SW948 CTRP2; CTRP1 5.0793 8.1228 4.5371 15.1905
HCT 8 CTRP2; CTRP1 5.3506 7.2908 5.1264 12.1917
DLD-1 CTRP2 5.5441 7.2621 5.3378 10.6214
LoVo CTRP2; CTRP1 5.6596 9.1064 4.7204 12.9284
LS1034 CTRP2 5.7248 8.1307 5.2023 10.6315
COLO201 CTRP2 5.747 8.2222 5.1865 10.6344
CCK-81 CTRP2 5.7659 8.2348 5.2007 10.5281
COLO205 CTRP2 5.7949 7.8083 5.4088 9.635
SW1116 CTRP2 5.7977 10.1094 4.3686 13.8088
SNU-1040 CTRP1 5.847 7.5016 5.5936 19.2687
RCM-1 [Human ESC] CTRP2; CTRP1 5.9557 9.0033 5.0633 10.8069
SNU-C5 CTRP2; CTRP1 5.9652 9.4797 4.849 11.6548
SNU-407 CTRP2 5.9818 7.7384 5.6344 8.246
SNU-61 CTRP2; CTRP1 6.0225 9.0011 5.1303 10.3709
SNU-C1 CTRP2 6.1345 11.5571 3.9784 14.6197
HCT 116 CTRP2; CTRP1 6.1434 8.6298 5.4227 8.888
SNU-81 CTRP1 6.5287 7.4257 6.3509 8.9812
HT-55 CTRP2; CTRP1 6.5586 8.1611 6.0504 5.3225
KM12 CTRP2; CTRP1 6.67 8.2294 6.1246 4.7549
SNU-175 CTRP1 6.7341 13.0573 3.7848 27.0266
LS513 CTRP2 6.7702 7.9708 6.3245 3.4725
LS411N CTRP2 6.7905 8.1608 6.25 3.738
RKO CTRP2; CTRP1 6.8298 9.7341 5.5259 6.9095
SNU-C4 CTRP2; CTRP1 6.9996 8.0378 6.5192 2.3887
CL-40 CTRP1 7.0783 9.644 5.7825 11.3832
NCI-H508 CTRP2; CTRP1 7.2203 8.5345 6.4509 2.2634
C2BBe1 CTRP2 7.251 13.5661 3.939 12.4767
CW-2 CTRP2; CTRP1 7.346 10.9766 5.3338 6.724
CL-34 CTRP1 7.5797 11.5574 5.2276 14.0694
HT-29 CTRP2; CTRP1 7.8925 9.6022 6.3965 1.529
OUMS-23 CTRP2 8.3164 10.4831 6.2143 1.5721
SNU-503 CTRP2 8.3297 13.7054 4.6978 7.526
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-886 CTRP2 -2.2422 2.8031 -2.3221 60.9909
JHH-2 CTRP2 1.1047 5.8563 0.8411 40.2646
SNU-423 CTRP2 1.3024 4.008 1.2789 38.3286
SNU-878 CTRP2 1.9466 2.9033 1.9466 33.9456
SNU-761 CTRP2 2.1113 6.1453 1.8742 33.611
JHH-4 CTRP2 2.9107 3.7103 2.9107 27.4982
SNU-387 CTRP2 2.9563 7.5285 2.4371 28.9631
SNU-449 CTRP2; CTRP1 2.9734 5.3751 2.9208 27.2566
SNU-182 CTRP2 3.0391 7.8238 2.4327 28.7138
Li-7 CTRP2 3.1525 7.7405 2.5832 27.8452
PLC/PRF/5 CTRP2 3.3689 5.9122 3.2743 24.7559
JHH-5 CTRP2 3.7744 6.4373 3.6187 22.2585
HLF CTRP2 4.2985 7.0027 4.055 19.0708
SK-HEP-1 CTRP2 5.877 8.8498 5.039 10.8892
SNU-398 CTRP2; CTRP1 5.9411 10.8923 4.1462 14.5747
HuH-1 CTRP2 7.0747 8.2997 6.4267 2.4139
JHH-1 CTRP2 7.1157 8.0141 6.6019 1.6013
Hep-G2 CTRP2; CTRP1 7.1565 9.4219 5.9577 4.4497
JHH-6 CTRP2; CTRP1 7.2673 10.6483 5.4092 6.3465
Hep 3B2.1-7 CTRP2 7.4328 11.2179 5.2561 6.6932
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 158 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HOP-92 CTRP2 -2.0401 0.0884 -2.0406 86.375
LC-1F CTRP2 0.6502 7.4466 -3.8958 18.0546
SW1573 CTRP2 1.0092 12.6475 -1.6198 44.0747
HOP-62 CTRP2 1.1468 5.4699 0.9576 39.8129
HCC44 CTRP2; CTRP1 1.1656 4.2232 1.1249 39.2927
PC-14 CTRP2 1.2721 3.2785 1.2688 41.1718
Calu-1 CTRP2 1.4288 5.3806 1.2751 37.868
HCC827 CTRP2; CTRP1 1.467 6.5616 1.0845 38.3683
RERF-LC-MS CTRP2 1.4948 4.215 1.4667 37.0578
NCI-H838 CTRP2 1.7371 3.8092 1.7302 35.3701
NCI-H1734 CTRP2 1.8918 4.3413 1.8696 34.3858
NCI-H1915 CTRP2; CTRP1 1.8986 4.2506 1.8809 34.3259
NCI-H1793 CTRP2 1.9197 6.9494 1.4734 35.485
Lu-99 CTRP2 1.9468 4.1646 1.9336 33.9885
HCC2279 CTRP2 2.0222 4.5486 1.9928 33.5379
NCI-H446 CTRP2 2.0727 4.1813 2.0617 33.1393
NCI-H1563 CTRP2 2.1337 6.7226 1.5738 30.0012
HCC78 CTRP2 2.4105 3.9211 2.4088 30.8492
SCLC-21H CTRP1 2.5534 7.2052 2.1012 59.6499
COR-L105 CTRP2 2.6183 6.2712 2.3983 30.194
HCC1438 CTRP2 2.6995 3.3192 2.6995 23.9353
NCI-H292 CTRP2 2.7195 4.9307 2.6919 28.8697
NCI-H2286 CTRP2; CTRP1 2.7588 5.2683 2.7054 28.6939
T3M-10 CTRP2; CTRP1 3.0464 9.661 1.7712 30.9528
HCC2108 CTRP2; CTRP1 3.13 5.788 3.0395 26.5184
SK-MES-1 CTRP2 3.1313 4.2676 3.1308 26.0245
NCI-H810 CTRP2; CTRP1 3.1566 6.9391 2.826 26.9939
LXF 289 CTRP2; CTRP1 3.214 4.7986 3.2067 25.4943
NCI-H647 CTRP2 3.2533 7.1873 2.8629 26.5602
NCI-H1703 CTRP2 3.3009 7.2371 2.9004 26.28
NCI-H1299 CTRP2; CTRP1 3.3103 5.5991 3.2528 25.0205
NCI-H1838 CTRP2 3.4844 7.5079 3.0185 25.294
NCI-H1155 CTRP2 3.5207 5.5868 3.4764 23.5682
EBC-1 CTRP2 3.5924 7.6254 3.0987 24.6776
NCI-H2087 CTRP2 3.5994 7.5998 3.1145 24.6
NCI-H1666 CTRP2; CTRP1 3.6199 7.9692 3.0134 24.8994
DMS 273 CTRP2; CTRP1 3.641 5.4171 3.6167 22.6957
NCI-H1048 CTRP1 3.6479 5.5023 3.3786 22.2157
COR-L279 CTRP1 3.6815 5.1437 3.5318 20.8028
NCI-H661 CTRP2; CTRP1 3.8156 6.4671 3.6572 21.993
SW1271 CTRP2 3.8891 6.3097 3.7678 22.8737
NCI-H2171 CTRP2 3.928 5.5116 3.9086 20.7597
LUDLU-1 CTRP2 3.9443 12.6429 1.3636 29.3101
LOU-NH91 CTRP2 3.9739 8.8573 3.0618 23.6785
NCI-H1693 CTRP2 3.9941 7.3208 3.6315 21.5336
NCI-H1339 CTRP2 4.0022 7.0945 3.7064 21.2372
NCI-H82 CTRP1 4.0637 7.7183 2.83 23.9911
HCC366 CTRP2 4.1247 9.3157 3.0341 23.3473
HCC1195 CTRP2; CTRP1 4.2016 7.6581 3.7586 20.6389
RERF-LC-KJ CTRP1 4.3445 7.8193 3.0459 20.9125
NCI-H23 CTRP2; CTRP1 4.3689 6.9847 4.1368 18.5594
NCI-H211 CTRP2 4.387 8.1364 3.7804 19.8243
NCI-H2030 CTRP2; CTRP1 4.4379 8.3293 3.7733 19.8988
NCI-H1341 CTRP2 4.4796 7.1095 4.223 17.9093
RERF-LC-A1 CTRP2 4.5208 7.2449 4.2285 17.7646
NCI-H1755 CTRP2; CTRP1 4.5293 8.5379 3.7898 19.578
NCI-H1355 CTRP2; CTRP1 4.5532 6.7759 4.3907 17.0785
NCI-H196 CTRP2 4.5837 8.0731 4.0149 18.3767
EKVX CTRP2 4.5896 8.245 3.5805 14.5537
HCC4006 CTRP2; CTRP1 4.6116 8.744 3.7942 19.3317
NCI-H2081 CTRP2; CTRP1 4.8041 7.8714 4.3366 16.7311
NCI-H1650 CTRP2 4.8186 10.0099 3.4471 19.9097
SBC-5 CTRP2 4.8266 8.3174 4.1802 17.061
LCLC-97TM1 CTRP2; CTRP1 4.8435 8.1803 4.2519 16.7391
LCLC-103H CTRP2; CTRP1 4.8492 6.7515 4.7188 14.9864
DV-90 CTRP2; CTRP1 4.8542 7.6302 4.4662 15.8965
Calu-3 CTRP2; CTRP1 4.8545 6.8286 4.7064 15.0139
Lu-65 CTRP2; CTRP1 4.8661 6.5944 4.7707 14.7495
COR-L88 CTRP2; CTRP1 4.9045 6.9979 4.7178 14.8188
NCI-H358 CTRP2 4.908 8.2557 4.291 16.4089
NCI-H2009 CTRP2; CTRP1 4.9222 7.1041 4.7076 14.8016
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 4.9282 8.1862 4.3397 16.1658
NCI-H2085 CTRP2 4.9282 9.8699 3.621 18.9537
NCI-H2228 CTRP2 4.9551 7.7253 4.5417 16.3974
NCI-H1395 CTRP2 4.9841 13.7756 1.8263 25.182
NCI-H1930 CTRP1 4.991 11.1825 1.9403 25.0896
NCI-H1975 CTRP2; CTRP1 5.0191 6.6676 4.9218 13.7334
SK-LU-1 CTRP2; CTRP1 5.0238 9.8895 3.7248 18.494
COR-L51 CTRP2; CTRP1 5.0578 7.2987 4.8051 14.2452
NCI-H2122 CTRP2; CTRP1 5.0639 7.3153 4.8066 14.2217
NCI-H1435 CTRP2; CTRP1 5.0982 7.7284 4.6947 14.3307
NCI-H522 CTRP2 5.1049 10.8048 3.3658 19.4826
NCI-H1581 CTRP2 5.1192 7.3103 4.8602 13.65
VMRC-LCD CTRP2; CTRP1 5.1794 8.1598 4.6168 14.4001
HCC15 CTRP2; CTRP1 5.1875 6.8803 5.0625 12.9187
EPLC-272H CTRP2; CTRP1 5.1926 8.0193 4.6863 14.0954
A-549 CTRP2; CTRP1 5.1961 8.1163 4.6518 14.2182
NCI-H1694 CTRP2; CTRP1 5.2103 7.1501 5.0158 13.0172
NCI-H1568 CTRP2; CTRP1 5.2667 7.1569 5.068 12.4445
NCI-H2405 CTRP2; CTRP1 5.3834 9.5827 4.2093 15.4689
NCI-H1573 CTRP2; CTRP1 5.3904 7.9756 4.9137 12.6688
NCI-H3255 CTRP1 5.4002 8.4208 4.7554 28.4366
CAL-12T CTRP2; CTRP1 5.4268 9.0586 4.5064 14.3772
NCI-H1792 CTRP2; CTRP1 5.4402 8.6696 4.6763 13.463
DMS 53 CTRP2 5.4507 10.3261 3.3907 13.2333
NCI-H1963 CTRP1 5.4634 6.5624 5.4238 23.0809
NCI-H2291 CTRP2 5.5593 12.1301 3.166 19.1291
HCC33 CTRP1 5.6093 10.6068 2.7292 17.6725
HCC1359 CTRP1 5.6332 7.6765 5.2994 22.9304
Sq-1 CTRP2; CTRP1 5.6808 9.1522 4.7208 12.8735
NCI-H1781 CTRP1 5.7236 18.8397 0.0217 41.273
COLO 668 CTRP2; CTRP1 5.8265 8.3284 5.2225 10.2822
NCI-H2023 CTRP2; CTRP1 5.8514 8.8349 5.0368 11.1741
NCI-H1836 CTRP1 5.8529 8.3972 5.2344 22.1182
NCI-H2106 CTRP2 5.8901 10.6201 4.2105 14.2343
ChaGo-K-1 CTRP2; CTRP1 5.8907 8.3314 5.287 9.8582
NCI-H322 CTRP2 5.9043 10.3683 4.3458 13.6499
NCI-H1184 CTRP2 5.9378 8.3171 5.3413 9.5193
DMS 114 CTRP2 6 9.8813 4.6717 12.0906
NCI-H596 CTRP1 6.0725 7.236 5.9293 15.1825
NCI-H2073 CTRP1 6.103 8.5164 5.4346 19.0815
DMS 454 CTRP2 6.2124 9.0457 5.276 9.1044
NCI-H1105 CTRP2; CTRP1 6.2328 7.2864 6.0864 6.0365
NCI-H1876 CTRP1 6.2335 11.7389 3.9998 28.2675
NCI-H2170 CTRP2 6.3368 10.0417 4.9091 10.3383
NCI-H841 CTRP2; CTRP1 6.3819 9.4198 5.2757 8.9253
LC-1/sq-SF CTRP2; CTRP1 6.3944 8.3148 5.7995 6.5211
NCI-H226 CTRP2 6.4013 11.7087 4.1434 14.2816
SHP-77 CTRP2; CTRP1 6.4071 10.0635 4.9629 9.9583
NCI-H2110 CTRP2; CTRP1 6.4502 9.3084 5.3938 8.2812
NCI-H2029 CTRP2; CTRP1 6.4597 11.5264 4.2858 12.6556
COR-L23 CTRP1 6.5227 8.1522 6.0196 11.8491
NCI-H1092 CTRP2 6.5631 10.3591 4.9574 9.6434
Calu-6 CTRP2; CTRP1 6.5644 9.2938 5.4855 7.4302
LK2 CTRP2 6.6009 7.033 6.5595 2.9645
NCI-H650 CTRP2; CTRP1 6.6214 10.2654 5.0557 9.1078
DMS 79 CTRP2 6.6299 12.3483 4.0256 13.3619
NCI-H1869 CTRP2 6.6602 11.1624 4.6433 10.7523
NCI-H727 CTRP2; CTRP1 6.6657 10.5552 4.9506 9.4552
NCI-H1373 CTRP2 6.8475 11.4118 4.6803 10.2153
NCI-H526 CTRP2 6.8704 11.4133 4.699 10.0915
KNS-62 CTRP2; CTRP1 6.8721 10.2295 4.5951 5.013
NCI-H441 CTRP2; CTRP1 6.8768 10.1779 5.3452 7.5726
NCI-H2172 CTRP2; CTRP1 6.9086 9.135 5.8931 5.2053
HCC1171 CTRP2 6.9676 13.5949 3.6904 14.022
NCI-H460 CTRP2; CTRP1 6.9723 7.9042 6.562 2.2649
NCI-H1651 CTRP2 6.9846 13.0508 3.2906 10.5261
NCI-H69 CTRP2 7.0389 16.5975 2.2486 19.1938
RERF-LC-Ad1 CTRP2 7.057 10.8961 5.1143 7.9821
MOR/CPR CTRP2 7.1204 8.4635 6.3818 2.5189
HCC2935 CTRP2; CTRP1 7.1341 11.2407 5.0303 8.3905
COLO 699 CTRP2; CTRP1 7.285 12.5086 4.52 10.2313
NCI-H520 CTRP2 7.301 11.2865 5.1179 7.5097
NCI-H1437 CTRP1 7.3726 11.886 3.3265 7.9265
NCI-H2342 CTRP2; CTRP1 7.4104 10.0771 5.8317 4.5245
NCI-H2126 CTRP2; CTRP1 7.445 11.0299 5.359 6.2405
RERF-LC-Ad2 CTRP2 7.5538 12.9522 4.4878 9.6784
NCI-H2141 CTRP1 7.5587 9.6005 6.1767 6.1015
NCI-H2196 CTRP2 7.6003 9.7087 6.1251 2.8021
COR-L95 CTRP2 7.6306 9.6202 6.1887 2.4991
NCI-H889 CTRP2 7.683 10.0907 5.9978 3.1986
HCC1588 CTRP2 7.6924 10.1394 5.9808 3.2543
HCC1833 CTRP2; CTRP1 7.7298 11.4547 5.392 5.8204
NCI-H1623 CTRP2 7.9177 11.7002 5.3811 5.37
BEN CTRP2; CTRP1 7.9931 8.8834 6.7235 0.2362
HCC95 CTRP2 8.9841 12.3335 5.7686 2.4857
NCI-H1944 CTRP2; CTRP1 10.7328 31.0529 -2.0583 23.9812
Hs 888.Lu CTRP2 2.9769 6.914 2.6366 28.22
⏷ Show the Full List of 158 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -9.4111 -7.085 -9.4111 98.4379
Yamato-SS CTRP2 7.3637 11.7703 4.9265 8.1976
BT-16 CTRP2 0.3303 2.7938 0.3246 44.7697
KYM-1 CTRP2 0.4913 3.9534 0.401 40.0113
TE 617.T CTRP2 0.8476 3.2677 0.8395 41.3203
SW982 CTRP2 1.3781 2.6372 1.378 37.7481
TTC-709 CTRP2 1.4244 6.6446 1.012 38.5701
A-204 CTRP2 1.7061 6.2693 1.4075 36.4553
HT-1080 CTRP2; CTRP1 1.7735 4.5206 1.7375 35.3791
SK-LMS-1 CTRP2 1.9612 3.9519 1.9544 33.8708
G-402 CTRP2 2.0886 5.7076 1.9316 33.5087
Rh18 CTRP2 2.6809 5.7771 2.5571 29.4529
SK-UT-1 CTRP2 2.8454 5.4507 2.7774 28.1647
MES-SA CTRP2 2.9255 3.645 2.9255 27.3988
Hs 729.T CTRP2 2.9572 6.9537 2.6045 28.3928
RKN CTRP2; CTRP1 3.0688 6.294 2.8868 27.2404
Rh41 CTRP2 3.1714 4.9565 3.1573 25.8019
GCT CTRP2 3.9434 7.8231 3.4139 22.4803
G-401 CTRP2; CTRP1 4.5177 6.6517 4.3805 17.2261
BT-12 CTRP2 4.757 11.7537 2.5787 23.2638
TE 441.T CTRP2 5.6764 7.681 5.3327 10.2587
RD CTRP2 5.7406 10.2936 4.2256 14.5253
Tm87-16 CTRP2 10.7941 21.8158 2.4837 12.1648
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 3.5017 5.4655 3.4675 23.661
P-STS CTRP2 5.2547 8.3168 4.6327 14.1313
SYO-1 CTRP2 9.2798 10.5575 6.6133 0.0794
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 4.2854 10.0881 2.8693 23.4947
A2780 CTRP2; CTRP1 0.0852 3.3275 0.0593 46.5689
OVKATE CTRP1 0.8669 4.949 0.7388 76.1401
OVCAR-8 CTRP2; CTRP1 1.5586 4.8786 1.4813 36.9375
OVSAHO CTRP2 1.9514 5.0214 1.8792 34.1503
COV434 CTRP2; CTRP1 1.9542 6.1582 1.7055 34.8398
MCAS CTRP2 2.0406 7.6822 1.3921 35.2725
OVCAR-5 CTRP2 2.2232 5.2804 2.1375 32.3806
OVK18 CTRP2; CTRP1 2.2965 6.6862 1.9584 32.8683
JHOM-1 CTRP2; CTRP1 2.5934 5.5381 2.501 30.1016
SNU-119 CTRP2 2.6914 6.3174 2.468 29.7192
HEY A8 CTRP2; CTRP1 2.7265 5.4417 2.6523 28.9803
OV-90 CTRP2; CTRP1 2.7599 5.5478 2.6769 28.9603
TOV-112D CTRP2 3.7149 7.0811 3.3966 23.2343
OVISE CTRP2 3.8651 5.8701 3.8095 21.3042
SNU-8 CTRP2 3.9192 6.3493 3.793 21.1873
Kuramochi CTRP2 3.9934 8.9738 3.036 23.7159
IGROV-1 CTRP2; CTRP1 4.1979 6.731 4.0197 19.7043
OC 314 CTRP2 4.4442 6.5755 4.1288 12.6704
JHOC-5 CTRP2; CTRP1 4.7198 6.7827 4.5759 16.1033
JHOS-4 CTRP1 4.791 6.9877 3.8631 11.9229
OVTOKO CTRP2 4.8625 11.7386 2.6887 22.6035
OAW28 CTRP2 4.9387 8.4647 4.2396 16.5221
SNU-840 CTRP2; CTRP1 4.955 9.9308 3.6366 19.014
OV56 CTRP2 4.9928 7.7663 4.5675 15.1147
SK-OV-3 CTRP2; CTRP1 4.9999 7.3391 4.7212 14.5185
COV362 CTRP2; CTRP1 5.0336 9.7836 3.7825 18.2446
TYK-nu CTRP2; CTRP1 5.1502 8.3186 4.5347 15.0032
RMG-I CTRP2; CTRP1 5.1706 10.7525 3.4725 19.0941
OAW42 CTRP2; CTRP1 5.1852 6.215 5.1683 12.5574
OVMANA CTRP1 5.2859 7.8359 3.8547 9.9162
FU-OV-1 CTRP2 5.4184 15.9185 1.1758 26.0653
COV318 CTRP1 5.5622 7.36 4.2959 5.0502
RMUG-S CTRP1 5.5979 8.7264 4.8283 26.6904
TOV-21G CTRP2 5.6432 8.1814 5.0958 11.2689
EFO-21 CTRP2; CTRP1 5.6775 9.6153 4.4858 13.6236
OV7 CTRP2; CTRP1 6.0056 9.3236 4.9622 11.0959
EFO-27 CTRP2; CTRP1 6.6089 9.1001 5.6426 6.8921
OVCAR-4 CTRP2; CTRP1 6.6247 10.6739 4.8779 10.0509
ONCO-DG-1 CTRP2 6.7814 9.6825 5.4865 6.9631
DOV13 CTRP2 6.8879 10.7264 5.0571 8.5543
COV644 CTRP2; CTRP1 7.0747 9.2315 5.9857 4.4868
JHOS-2 CTRP2 7.2476 12.239 4.5993 9.7772
Caov-3 CTRP2; CTRP1 7.2895 10.583 5.4851 6.1915
ES2 CTRP2 7.7601 12.7562 4.7447 8.2576
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.9727 12.0201 4.482 10.7925
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2; CTRP1 1.5869 5.1635 1.4754 36.6994
IST-Mes1 CTRP2 3.1779 6.5135 2.954 26.4805
NCI-H28 CTRP2; CTRP1 3.353 6.3503 3.1794 25.1368
MPP 89 CTRP2 3.3573 5.2158 3.3354 24.5851
ACC-MESO-1 CTRP2 3.4053 5.6763 3.3447 24.3958
NCI-H2052 CTRP2; CTRP1 4.5755 8.525 3.8315 19.0963
NCI-H2452 CTRP2 5.0518 12.4258 2.543 24.0615
JL-1 CTRP2 6.7925 11.998 4.3405 11.7378
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP2; CTRP1 1.9741 4.4574 1.9484 33.8473
LNCaP clone FGC CTRP2 5.1857 8.3526 4.5455 14.6588
22Rv1 CTRP2 5.3537 9.356 4.2829 15.2509
DU145 CTRP2 5.9155 8.8008 5.1 10.5461
VCaP CTRP2 6.3235 10.1127 4.8621 10.5633
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 2.0725 7.284 1.5468 34.727
A-253 CTRP2 5.7519 9.7797 4.4812 13.4611
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LMSU CTRP2 0.5547 2.7886 0.5511 43.2651
SNU-16 CTRP2 1.0883 4.3415 1.0354 39.842
Hs 746.T CTRP2 1.2125 5.2296 1.0662 39.2725
SNU-1 CTRP2 2.2551 5.4271 2.1525 32.2235
ECC12 CTRP2 2.3338 2.9995 2.3338 31.3563
SNU-719 CTRP2 2.6763 7.0611 2.2687 30.4329
SNU-216 CTRP2 2.6813 5.7025 2.4615 24.8795
GSS CTRP2 2.9819 4.9244 2.9637 27.0831
MKN1 CTRP2 3.1532 5.2804 3.1183 25.994
ECC10 CTRP2 3.5594 6.1345 3.4432 23.5574
SH-10-TC CTRP2; CTRP1 3.8534 6.4175 3.7083 21.6935
HuG1-N CTRP2 3.9258 11.7647 1.7512 28.2278
MKN74 CTRP2; CTRP1 4.4423 7.9223 3.9181 19.1479
SNU-668 CTRP2 4.5126 8.3907 3.8177 19.3257
SNU-620 CTRP2 4.757 8.1817 4.1591 17.3374
SNU-5 CTRP2 4.8674 8.0491 4.3278 16.382
HGC-27 CTRP2 5.0951 7.3154 4.8323 13.825
NUGC-4 CTRP2; CTRP1 5.1474 7.208 4.9226 13.3359
NCC-StC-K140 CTRP2 5.1806 7.6483 4.8124 13.6492
KATO III CTRP2 5.2993 7.8066 4.8817 13.0469
23132/87 CTRP2 5.4912 6.6953 5.428 10.4575
AGS CTRP2; CTRP1 5.5834 6.9551 5.4758 10.2179
KE-39 CTRP2 5.8251 11.1147 3.9091 15.6034
NCI-N87 CTRP2 5.8824 7.986 5.4277 9.3232
MKN7 CTRP2; CTRP1 6.1607 8.3482 5.5527 8.1013
NUGC-3 CTRP2 6.3143 9.3642 5.2193 9.1008
SNU-601 CTRP2 6.3752 9.1347 4.7656 5.1231
IM95 CTRP2 7.2197 15.6423 2.8757 16.6308
MKN45 CTRP2 8.2178 9.3269 6.6494 0.3022
OCUM-1 CTRP2 8.8127 28.5619 -2.2942 27.3025
Fu97 CTRP2; CTRP1 10.851 19.5197 3.6032 8.2526
SNG-M CTRP2; CTRP1 2.1072 4.2801 2.0935 32.9176
SNU-685 CTRP2 2.446 4.9535 2.4054 30.742
SNU-1077 CTRP2 2.8527 4.7232 2.8401 27.9284
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-238 CTRP2 0.0876 2.2119 0.0861 46.3821
B-CPAP CTRP2 1.2555 2.0474 1.2555 38.568
8505C CTRP2 2.0896 6.2185 1.8354 33.8078
SW579 CTRP2 2.57 5.0262 2.5291 29.9144
FTC-133 CTRP2 2.8262 6.0915 2.6594 28.6296
8305C CTRP2 3.3497 7.457 2.8876 26.1728
TT2609-C02 CTRP2 3.8241 7.8816 3.2646 23.3806
CGTH-W-1 CTRP2 3.941 6.8758 3.6985 21.4541
ML-1 [Human leukemia] CTRP2 4.7414 6.5119 4.6515 16.658
CAL-62 CTRP2 5.1548 10.5023 3.5564 18.6219
BHT-101 CTRP2 5.6649 9.9218 4.3293 14.2882
TT CTRP2 5.8562 8.4858 5.1832 10.3616
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-25 CTRP2 2.127 6.3542 1.8464 33.6428
SNU-46 CTRP2 2.2725 8.318 1.4348 34.334
SCC-4 CTRP2 2.2881 5.8443 2.1231 32.208
YD-8 CTRP2 2.3895 8.4445 1.5173 33.6993
SNU-1214 CTRP2 2.5276 5.7083 2.4034 30.4774
HSC-2 CTRP2; CTRP1 2.8378 4.2986 2.8354 27.9938
PE/CA-PJ49 CTRP2 3.0174 4.1223 3.017 26.7859
HSC-3 CTRP2 3.0634 5.3654 3.0166 26.635
CAL-27 CTRP2 3.4184 4.4631 3.4179 24.1042
SNU-1041 CTRP2 3.5868 8.8116 2.6681 26.2188
SCC-9 CTRP2; CTRP1 3.9073 6.7345 3.7024 21.7356
BICR 56 CTRP2 4.0682 8.3539 3.3572 22.3225
SNU-899 CTRP2 4.0784 7.9065 3.531 21.6506
CAL-33 CTRP2 4.2235 6.5546 3.8977 14.2847
BICR 18 CTRP2 4.3349 6.8802 4.1271 18.6992
BICR 6 CTRP2 4.6789 7.727 4.2429 17.2436
FaDu CTRP2 4.688 6.762 4.5409 16.1228
SNU-1076 CTRP2 4.7509 7.766 4.3068 16.7949
PE/CA-PJ34 (clone C12) CTRP2 4.7658 7.5583 4.395 16.4215
PE/CA-PJ15 CTRP2 4.8286 9.0269 3.8898 18.1764
BHY CTRP2 5.4158 8.5894 4.6859 13.4892
PE/CA-PJ41 (clone D2) CTRP2 5.4488 9.2816 4.4125 14.491
YD-10B CTRP2 5.5605 8.6282 4.818 12.5852
BICR 31 CTRP2 5.8524 8.97 4.9591 11.2735
HSC-4 CTRP2 5.9928 12.6427 3.314 17.5614
SNU-1066 CTRP2 6.013 8.7321 5.2287 9.7816
BICR 22 CTRP2 6.0179 9.1228 5.0509 10.4934
Detroit 562 CTRP2 7.5297 10.8867 5.495 5.5255
BICR 16 CTRP2 9.2291 42.7217 -9.7124 34.1579
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 CTRP2; CTRP1 0.6205 4.9211 0.4772 43.1377
JMSU-1 CTRP2 2.6328 4.5749 2.6206 29.3977
647V CTRP2 2.7836 4.4354 2.7783 28.3659
SW1710 CTRP2 2.9742 5.6675 2.8872 27.3686
RT-112 CTRP2 3.1481 5.2293 3.117 26.0153
SCaBER CTRP2 3.6269 5.866 3.5566 22.9472
T24 CTRP2 3.7477 6.9349 3.4721 22.8626
BC-3C CTRP2 3.7597 5.3427 3.7443 21.872
TCCSUP CTRP2 3.9117 6.9471 3.6479 21.726
HT-1376 CTRP2; CTRP1 4.3645 8.2022 3.7317 20.0719
KMBC-2 CTRP2; CTRP1 4.7774 8.5899 4.0187 17.8186
U-BLC1 CTRP2 4.8161 8.2473 4.1966 17.0276
HT-1197 CTRP2 5.2484 9.1746 4.2575 15.6237
UM-UC-1 CTRP2 5.2793 8.1244 4.7368 13.6598
KU-19-19 CTRP2 5.3145 7.8557 4.8794 13.0131
UM-UC-3 CTRP2; CTRP1 5.4476 9.9473 4.1043 15.7277
639V CTRP2 5.8111 7.0048 5.7053 8.4718
BFTC-905 CTRP2 6.0287 7.3768 5.824 7.3869
253J-BV CTRP2 6.3221 8.887 5.4573 8.099
CAL-29 CTRP2 6.3239 10.219 4.8102 10.7781
J82 CTRP2 6.7799 9.2192 5.7159 6.0013
VM-CUB-1 CTRP2 7.0132 11.358 4.8469 9.1902
RT-4 CTRP2; CTRP1 8.3095 13.7865 4.6437 7.7762
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 5.3168 7.1947 5.1113 12.1351

References

1 Human intestinal transporter database: QSAR modeling and virtual profiling of drug uptake, efflux and interactions. Pharm Res. 2013 Apr;30(4):996-1007.