Details of the Drug

General Information of Drug (ID: DMGLSPC)

• Drug Name: Salicylhydroxamic acid
• Synonyms: Salicylhydroxamic acid; N,2-Dihydroxybenzamide; 89-73-6; 2-Hydroxybenzohydroxamic acid; Salicylohydroxamic acid; SHAM; Salicylohydroximic acid; Benzamide, N,2-dihydroxy-; 2-Hydroxybenzhydroxamic acid; O-Hydroxybenzohydroxamic acid; SalicylhydroxaMicacid; SHA; 2,N-Dihydroxy-benzamide; NSC 5088; NSC 193440; Saliaylhydroxamic acid; UNII-8Q07182D0T; 2-hydroxybenzenecarbohydroxamic acid; Salicylic Hydroxamic Acid; EINECS 201-934-3; Salicylhydroxamic acid, 99%; MLS000069410; CHEMBL309339; CHEBI:45615; NSC5088

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 153.14
  Logarithm of the Partition Coefficient (xlogp); 0.9
  Rotatable Bond Count (rotbonds); 1
  Hydrogen Bond Donor Count (hbonddonor); 3
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C7H7NO3
  IUPAC Name: N,2-dihydroxybenzamide
  Canonical SMILES: C1=CC=C(C(=C1)C(=O)NO)O
  InChI: InChI=1S/C7H7NO3/c9-6-4-2-1-3-5(6)7(10)8-11/h1-4,9,11H,(H,8,10)
  InChIKey: HBROZNQEVUILML-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 66644
  ChEBI ID: CHEMBL309339
  CAS Number: 89-73-6
  UNII: 8Q07182D0T
  DrugBank ID: DB03819
  TTD ID: D0H6QL
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase)	TT3PQ2Y	PYRD_PLAF7	Inhibitor	[1]

References

• [1] Effects of atovaquone and other inhibitors on Pneumocystis carinii dihydroorotate dehydrogenase. Antimicrob Agents Chemother. 1995 Feb;39(2):325-8.