Details of the Drug

General Information of Drug (ID: DMGQ0ZI)

Drug Name
Pralidoxime Chloride
Synonyms Protopam Chloride
Indication
Disease Entry ICD 11 Status REF
Poisoning due to pesticides and chemicals NE6Z Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 172.61
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 1
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 3
Chemical Identifiers
Formula
C7H9ClN2O
IUPAC Name
(NE)-N-[(1-methylpyridin-1-ium-2-yl)methylidene]hydroxylamine;chloride
Canonical SMILES
C[N+]1=CC=CC=C1/C=N/O.[Cl-]
InChI
InChI=1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H
InChIKey
HIGSLXSBYYMVKI-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
135445761
ChEBI ID
CHEMBL748
CAS Number
51-15-0
TTD ID
D0X7NU
ACDINA ID
D01354
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug
Drug Pharmacogenomic Perturbation (DPP)NEW Click to Jump to the Detailed DPP Information of This Drug
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Acetylcholinesterase (AChE) TT1RS9F ACES_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Poisoning due to pesticides and chemicals
ICD Disease Classification NE6Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Acetylcholinesterase (AChE) DTT ACHE 6.39E-02 -1.07 -1.15
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Drug Inactive Ingredient(s) (DIG) and Formulation(s) of This Drug

DIG
DIG Name DIG ID PubChem CID Functional Classification
Sodium hydroxide E00234 14798 Alkalizing agent
Pharmaceutical Formulation
Formulation Name Drug Dosage Dosage Form Route
Pralidoxime Chloride 1g powder 1g Powder Intravenous; Intramuscular; Subcutaneous
Jump to Detail Pharmaceutical Formulation Page of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.