Details of the Drug

General Information of Drug (ID: DMH7W9X)

Drug Name
SNDX-275
Synonyms
Entinostat; Histone Deacetylase Inhibitor I; IN1470; MS 275; SNDX 275; MS 27-275; Ms-275; Entinostat (USAN/INN); MS-27-275; Pyridin-3-ylmethyl 4-(2-aminophenylcarbamoyl)benzylcarbamate; Pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate; Pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Pyridin-3-ylmethyl{4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Carbamic acid, [[4-[[(2-aminophenyl)amino]carbonyl]phenyl] methyl]-, 3-pyridinylmethyl ester; Carbamic acid, [[4-[[(2-aminophenyl)carbaonyl]phenyl]methyl]-, 3-pyridinylmethyl ester; Entinostat, SNDX-275, MS-27-275, MS-275; N-(2-Aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]benzamide; N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide; Carbamic acid, ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)-, 3-pyridinylmethyl ester; 3-Pyridinylmethyl ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)carbamate
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Phase 3 [1]
Colorectal cancer 2B91.Z Phase 2 [2]
Melanoma 2C30 Phase 2 [2]
Non-small-cell lung cancer 2C25.Y Phase 2 [2]
Ovarian cancer 2C73 Phase 2 [2]
ATC Code
L01XH05: SNDX-275
L01XH: Histone deacetylase (HDAC) inhibitors
L01X: OTHER ANTINEOPLASTIC AGENTS
L01: ANTINEOPLASTIC AGENTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 376.4
Logarithm of the Partition Coefficient (xlogp) 2
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C21H20N4O3
IUPAC Name
pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
Canonical SMILES
C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
InChI
InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
InChIKey
INVTYAOGFAGBOE-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
4261
ChEBI ID
CHEBI:132082
CAS Number
209783-80-2
UNII
1ZNY4FKK9H
DrugBank ID
DB11841
TTD ID
D0M8FD
VARIDT ID
DR00732
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase (HDAC) TTBH0VX NOUNIPROTAC Inhibitor [2]
Histone deacetylase 1 (HDAC1) TT6R7JZ HDAC1_HUMAN Inhibitor [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) OTX1DWEF DHB8_HUMAN Gene/Protein Processing [4]
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1) OTG2T749 CP24A_HUMAN Gene/Protein Processing [4]
1,4-alpha-glucan-branching enzyme (GBE1) OTK2N05B GLGB_HUMAN Gene/Protein Processing [4]
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) OT5I4Y9K PLCB_HUMAN Gene/Protein Processing [5]
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (PNPLA3) OTR4990X PLPL3_HUMAN Gene/Protein Processing [5]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1) OT6Z1L2E PLCH1_HUMAN Gene/Protein Processing [5]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2) OTGVC9MY PLCG2_HUMAN Gene/Protein Processing [4]
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) OTHF4H9U DHI2_HUMAN Gene/Protein Processing [5]
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Gene/Protein Processing [4]
15-hydroxyprostaglandin dehydrogenase (HPGD) OTYZI6JB PGDH_HUMAN Gene/Protein Processing [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Breast cancer
ICD Disease Classification 2C60-2C65
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Histone deacetylase 1 (HDAC1) DTT HDAC1 6.73E-02 0.24 0.59
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 3.1852 6.0559 1.8394 9.7845
NOS-1 [Human HNSCC] GDSC1; GDSC2 -1.9971 0.7165 -2.03 53.2584
ES8 GDSC1; GDSC2 -1.1131 2.6459 -1.3517 45.0805
ES1 GDSC1 -0.249 5.1782 -1.5688 38.2238
CHSA0108 GDSC2 0.0123 4.7828 -0.7726 36.5118
HuO9 GDSC2 0.3861 2.9658 0.2077 30.3609
SK-PN-DW GDSC1; GDSC2 0.431 3.707 0.054 30.8918
ES4 GDSC1; GDSC2 0.5528 4.4948 -0.0854 30.9509
ES6 GDSC1; GDSC2 0.7065 5.2415 -0.2156 30.8048
EW-12 GDSC1; GDSC2 0.9939 4.2155 0.4915 26.0175
SW1353 CTRP2 1.1373 2.9077 1.1336 32.7042
EW-16 GDSC1; GDSC2 1.1588 6.1993 -0.1626 28.5243
EW-7 GDSC2 1.2316 4.6152 0.5922 24.4232
SK-N-MC CTRP2 1.3953 2.0802 1.3953 30.9726
NY GDSC2 1.4179 3.1184 1.2958 19.7434
U2OS GDSC2; CTRP2 1.4714 4.2536 1.4047 36.2932
EW-1 GDSC1; GDSC2 1.6431 5.2861 0.7376 21.891
ES5 GDSC1; GDSC2 1.6556 4.5295 1.0744 19.9366
MHH-ES-1 GDSC2; CTRP2 1.7337 4.1777 1.6885 34.1514
CHSA8926 GDSC2 1.758 6.3958 0.3448 23.5584
EW-22 GDSC1; GDSC2 1.808 5.4097 0.8498 20.5982
CADO-ES1 GDSC2 1.8583 5.5739 0.8256 20.5373
EW-18 GDSC1; GDSC2 1.8603 5.3597 0.9252 19.962
A-673 GDSC2; CTRP2 1.8913 4.4659 1.8255 27.8901
TC71 CTRP2 2.1101 3.2646 2.1095 26.2131
TC-71 GDSC1; GDSC2 2.1249 4.6235 1.5228 15.4234
ES7 GDSC1; GDSC2 2.2926 5.1783 1.4404 15.2722
SK-ES-1 GDSC1; GDSC2; CTRP2 2.3105 4.9846 2.2023 25.2433
EW-3 GDSC1; GDSC2 2.3485 4.8554 1.6453 13.8273
SaOS-2 GDSC2; CTRP2 2.3585 4.5967 2.3053 24.7355
CAL-78 GDSC2; CTRP2 2.3635 9.2752 0.8447 29.6227
EW-11 GDSC1; GDSC2 2.5309 7.4835 0.55 19.6112
CHSA0011 GDSC2 2.7298 10.3952 -0.7195 25.0566
EW-24 GDSC1; GDSC2 3.0965 6.6496 1.4667 12.3796
CAL-72 GDSC2 3.7543 5.4274 2.6042 3.4308
U-CH2 GDSC2 3.8217 6.9282 1.9165 7.5387
HOS GDSC2; CTRP2 3.9284 7.5532 3.2005 16.7824
EW-13 GDSC1; GDSC2 4.1253 8.366 1.4341 9.7372
HuO-3N1 GDSC2 4.3214 6.7791 2.3384 3.85
SJSA-1 GDSC1; CTRP2 4.697 13.0692 1.3544 21.7844
G-292 clone A141B1 GDSC2; CTRP2 4.8831 13.0255 1.5444 20.7016
H-EMC-SS GDSC1; GDSC2 5.3384 8.7173 2.0616 3.6759
Hs 888.T CTRP2 5.5046 9.0671 4.0626 9.4328
MG-63 GDSC2; CTRP2 6.243 10.8383 3.8108 9.0025
Hs 822.T CTRP2 7.4723 8.4106 5.7409 0.0987
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -1.1235 4.5013 -1.4173 47.9815
MEC1 CTRP2 0.9437 4.0758 0.8662 34.2342
JM1 GDSC1; GDSC2; CTRP2 -1.0676 0.7777 -1.068 47.3821
ALL-PO GDSC1; GDSC2 -3.6923 -0.6873 -3.7085 68.9685
EoL-1 GDSC1; GDSC2; CTRP2 -3.0967 0.5406 -3.1098 60.6293
SUP-B8 GDSC2 -2.8786 -0.28 -2.891 61.8034
697 GDSC1; GDSC2; CTRP2 -2.8074 0.5785 -2.8172 58.8175
KMS-34 CTRP2 -2.7522 -0.5119 -2.7526 58.5904
CRO-AP2 GDSC1; GDSC2 -2.48 -0.6234 -2.4817 58.1701
Ki-JK CTRP2 -2.474 1.1077 -2.4914 56.6084
Karpas-231 GDSC1; GDSC2 -2.4725 -1.0456 -2.4727 58.1384
NB4 GDSC1; GDSC2 -2.4301 -0.2944 -2.4353 57.6214
H9 GDSC1; GDSC2 -2.2964 -1.2068 -2.2964 56.3794
BCP-1 CTRP2 -2.2299 1.3185 -2.2491 55.0238
Mino CTRP2 -2.222 -0.4787 -2.222 55.0708
VL51 GDSC1; GDSC2 -2.2124 -0.6721 -2.2129 55.5277
WIL2 NS GDSC1; GDSC2 -2.1417 0.1208 -2.1519 54.7495
OCI-Ly7 GDSC2 -1.9482 -0.0838 -1.9516 52.8695
JSC-1 GDSC1; GDSC2 -1.7789 -0.0355 -1.7814 51.1826
A3/Kawakami GDSC1; GDSC2; CTRP2 -1.6927 0.204 -1.6929 51.545
Karpas-45 GDSC1; GDSC2 -1.6842 -0.2366 -1.6849 50.237
SEM CTRP2 -1.6467 -0.3847 -1.6467 51.2393
BV-173 GDSC1; CTRP2 -1.6355 2.0553 -1.6698 51.1378
Kasumi-1 GDSC1; GDSC2; CTRP2 -1.5989 -0.2387 -1.5989 50.9208
KMS-20 CTRP2 -1.5684 1.5977 -1.5829 50.7097
MOLT-13 GDSC1; GDSC2 -1.5298 0.3288 -1.5353 48.695
NU-DUL-1 GDSC1; GDSC2; CTRP2 -1.527 -0.1411 -1.527 50.4418
SCC-3 GDSC1; GDSC2 -1.5179 3.2341 -1.9362 48.8284
DoHH2 GDSC1; GDSC2; CTRP2 -1.4633 3.7418 -1.6545 50.0157
OPM-2 GDSC1; GDSC2; CTRP2 -1.389 0.4189 -1.3892 49.5224
ATN-1 GDSC1; GDSC2 -1.3757 0.261 -1.3784 47.1483
MOTN-1 CTRP2 -1.3012 0.7042 -1.3018 48.9382
NU-DHL-1 CTRP2 -1.2843 0.6622 -1.2848 48.8255
RCH-ACV GDSC2; CTRP2 -1.2758 2.3043 -1.3119 48.7925
MOLM-16 GDSC2 -1.2034 1.1697 -1.2357 45.5051
SU-DHL-6 GDSC1; GDSC2; CTRP2 -1.1611 2.0764 -1.1831 56.6009
KMS-28BM CTRP2 -1.1506 5.3091 -1.6198 48.2331
Peer CTRP2 -1.1182 0.2888 -1.1182 47.7184
MHH-CALL-4 GDSC2; CTRP2 -1.1099 0.6882 -1.1102 47.6635
BL-70 CTRP2 -1.078 1.6827 -1.0867 47.4637
Ramos.2G6.4C10 GDSC1; GDSC2 -1.0736 2.283 -1.2366 44.5541
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 -1.0692 1.662 -1.0774 47.4048
SU-DHL-5 GDSC2 -1.0476 0.1131 -1.0479 43.8497
SET-2 CTRP2 -0.9955 1.1126 -0.9968 46.9035
KMS-21-BM CTRP2 -0.9855 0.3752 -0.9855 46.8343
SU-DHL-1 GDSC1; GDSC2; CTRP2 -0.9811 1.2138 -0.9828 46.8084
KOPN-8 GDSC1; GDSC2 -0.9694 0.6073 -0.973 43.0792
SU-DHL-8 GDSC1; GDSC2; CTRP2 -0.9592 0.305 -0.9592 50.1169
MHH-CALL-2 GDSC2 -0.8966 0.9259 -0.9068 42.3768
MY-M12 GDSC1; GDSC2 -0.8854 0.9487 -0.8961 42.2664
ARH-77 GDSC1; GDSC2 -0.8693 4.5664 -1.6436 43.9509
Namalwa GDSC1; GDSC2; CTRP2 -0.8428 3.7498 -0.9923 46.1074
RPMI-8402 GDSC1; CTRP2 -0.8372 0.9876 -0.8377 45.8475
MV4-11 GDSC1; CTRP2 -0.8103 0.4039 -0.8104 53.1753
ALL-SIL GDSC1; GDSC2; CTRP2 -0.7934 0.0551 -0.7934 45.5543
EM-2 GDSC1; GDSC2; CTRP2 -0.7679 1.2725 -0.7691 45.3874
BL-41 GDSC1; GDSC2 -0.7571 1.5513 -0.7995 41.1096
SK-MM-2 GDSC1; GDSC2; CTRP2 -0.7456 1.1082 -0.7461 45.2373
OCI-Ly3 CTRP2 -0.726 3.4349 -0.8292 45.292
BE-13 GDSC1; GDSC2 -0.7183 1.3943 -0.7466 40.6666
KMS-12-BM GDSC2; CTRP2 -0.6931 1.6901 -0.6975 44.8973
SIG-M5 GDSC1; GDSC2; CTRP2 -0.6735 1.1548 -0.674 44.7572
Sc-1 GDSC1 -0.6572 1.5238 -0.7513 37.7624
Karpas-299 GDSC1; GDSC2 -0.6339 0.7261 -0.6359 39.7067
MOLM-13 GDSC1; GDSC2; CTRP2 -0.6324 1.2532 -0.6331 44.4838
MOLT-16 GDSC1; GDSC2; CTRP2 -0.5973 0.774 -0.5973 44.248
KE-37 GDSC1; GDSC2 -0.5754 0.8858 -0.5792 39.1287
Kasumi-2 CTRP2 -0.5718 1.1564 -0.5721 44.0788
MOLP-8 GDSC1; GDSC2; CTRP2 -0.5696 1.6034 -0.5721 44.0703
SUP-B15 GDSC1; GDSC2; CTRP2 -0.5678 1.488 -0.5694 44.0561
BC-3 GDSC1; GDSC2 -0.5041 4.2137 -1.1271 40.5452
M-07e CTRP2 -0.4864 0.7708 -0.4864 43.5093
HuT 78 CTRP2 -0.4699 1.1694 -0.4702 43.4002
MM1.S GDSC2; CTRP2 -0.467 0.7217 -0.467 43.3797
A4/Fukuda GDSC1; GDSC2; CTRP2 -0.4452 1.3877 -0.4459 43.237
GA-10 GDSC1; GDSC2; CTRP2 -0.4336 3.8756 -0.5728 43.4617
Ri-1 CTRP2 -0.4127 4.6426 -0.6752 43.5494
HC-1 GDSC1; GDSC2 -0.3947 4.6274 -1.153 39.9718
DEL GDSC1; GDSC2; CTRP2 -0.3743 1.1021 -0.3743 42.7623
NCO2 CTRP2 -0.3704 2.3499 -0.3843 42.7746
SKM-1 GDSC1; GDSC2; CTRP2 -0.3526 1.4905 -0.3534 42.6201
BONNA-12 GDSC2 -0.3507 1.3178 -0.3627 36.9136
Loucy GDSC1; GDSC2 -0.3332 1.6347 -0.363 36.8225
BALL-1 GDSC1; GDSC2 -0.332 2.4757 -0.4707 37.291
Mono-Mac-1 CTRP2 -0.3108 5.5196 -0.7553 43.2167
Daudi GDSC1; GDSC2; CTRP2 -0.3051 3.0889 -0.3549 42.4306
L-363 GDSC1; GDSC2; CTRP2 -0.3 1.7553 -0.3021 42.2736
CML-T1 GDSC2; CTRP2 -0.2921 1.4551 -0.2927 42.2165
ST486 GDSC1; GDSC2; CTRP2 -0.2655 2.4031 -0.2789 42.0761
JeKo-1 GDSC2; CTRP2 -0.2569 1.9978 -0.2614 41.9937
KE-97 CTRP2 -0.2528 2.2416 -0.2617 52.4078
HuNS1 CTRP2 -0.1908 3.276 -0.2503 41.6993
HPB-ALL CTRP2 -0.1804 1.3 -0.1805 41.4706
KMS-11 GDSC2 -0.1079 1.4574 -0.1193 34.4755
NALM-6 GDSC1; GDSC2; CTRP2 -0.1065 1.1983 -0.1066 48.4803
LAMA-84 GDSC1; GDSC2; CTRP2 -0.102 2.6037 -0.1186 48.4626
OCI-AML-3 GDSC1; GDSC2; CTRP2 -0.0776 2.2113 -0.0835 40.804
F-36P CTRP2 -0.0418 1.5765 -0.0421 40.5481
QIMR-WIL GDSC1; GDSC2 -0.0259 4.8503 -0.8389 36.9454
RPMI-8226 GDSC1; GDSC2; CTRP2 -0.0214 1.9723 -0.0237 40.4184
MHH-PREB-1 GDSC1; GDSC2 -0.0099 4.0537 -0.5375 35.7635
SUP-M2 GDSC1; GDSC2; CTRP2 -0.0065 1.7836 -0.0075 40.3151
NK-92MI GDSC1; GDSC2 0.0096 2.1185 -0.0494 33.5307
MOLT-3 CTRP2 0.011 2.3681 0.0033 40.2193
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 0.0337 2.3037 0.0275 40.0636
MC116 GDSC1; GDSC2; CTRP2 0.0385 2.7175 0.0209 40.0658
CA46 GDSC1; GDSC2; CTRP2 0.0386 4.9081 -0.2383 40.7108
P31/FUJ GDSC1; CTRP2 0.0396 1.6924 0.0391 40.0063
RPMI-6666 GDSC1; GDSC2; CTRP2 0.0423 3.7586 -0.0523 40.2514
EHEB GDSC1; CTRP2 0.0691 3.8106 -0.0299 40.0868
SR GDSC1; GDSC2; CTRP2 0.0943 3.916 -0.0158 39.9498
CESS GDSC1; GDSC2 0.1072 2.0533 0.0614 32.4888
PL-21 GDSC1; GDSC2 0.1576 5.012 -0.7048 35.5032
P12-Ichikawa GDSC2; CTRP2 0.1715 0.9224 0.1715 39.126
SUP-HD1 GDSC1; GDSC2; CTRP2 0.1715 4.2616 0.0192 39.5526
LC4-1 GDSC1; GDSC2 0.177 2.3559 0.0971 31.9585
EB1 CTRP2 0.2471 3.816 0.158 38.886
OCI-AML-2 GDSC1; GDSC2 0.2579 1.1251 0.2576 30.7495
PF-382 GDSC1; GDSC2 0.2589 1.7732 0.2429 30.8185
KMS-18 CTRP2 0.261 2.2512 0.2579 38.54
OCI-M1 GDSC1; GDSC2; CTRP2 0.2933 1.8497 0.2929 38.3157
OCI-Ly19 GDSC1; GDSC2 0.3001 2.341 0.231 30.6724
Farage GDSC1; GDSC2 0.3291 4.8465 -0.458 33.6752
L-540 GDSC1; GDSC2; CTRP2 0.3333 2.283 0.3305 38.0574
CTV-1 GDSC1; GDSC2 0.3454 1.2578 0.3448 29.8729
MOLP-2 CTRP2 0.4659 3.31 0.4316 37.2737
JURL-MK1 GDSC1; GDSC2; CTRP2 0.4721 2.5906 0.4661 37.143
MLMA GDSC1; GDSC2 0.484 3.7661 0.0931 30.4418
RL GDSC1; GDSC2; CTRP2 0.4864 3.4315 0.4446 37.1608
SU-DHL-4 GDSC1; GDSC2; CTRP2 0.4878 2.4949 0.4836 37.0328
Karpas-422 GDSC1; GDSC2; CTRP2 0.4914 4.7191 0.2879 37.597
HEL GDSC1; GDSC2; CTRP2 0.5035 1.9376 0.5033 43.6727
SU-DHL-16 GDSC1; GDSC2 0.5243 2.172 0.4892 28.2522
OCI-AML-5 GDSC1; GDSC2; CTRP2 0.5349 1.6717 0.5348 36.7054
HT GDSC1; GDSC2; CTRP2 0.5427 3.0099 0.5261 36.7072
BC-1 GDSC1; GDSC2 0.5499 3.3624 0.2856 29.1657
KCL-22 GDSC1; GDSC2; CTRP2 0.5838 3.0728 0.5656 43.096
HDLM-2 GDSC1; GDSC2; CTRP2 0.6305 5.1976 0.1847 39.2455
DND-41 GDSC1; GDSC2; CTRP2 0.6623 2.4102 0.6605 35.8621
HEL 92.1.7 CTRP2 0.6671 1.9783 0.667 35.8245
EJM GDSC1; GDSC2; CTRP2 0.669 2.0496 0.6688 35.8124
ML-2 GDSC1; GDSC2 0.6744 2.437 0.6173 26.8586
Jurkat GDSC2; CTRP2 0.6945 2.5208 0.6918 42.1763
DB GDSC1; GDSC2; CTRP2 0.7069 3.0094 0.6941 35.6011
P30/OHK GDSC1; GDSC2 0.7337 3.7425 0.3723 27.8431
HL-60 GDSC1; GDSC2; CTRP2 0.7359 2.2044 0.7354 35.3676
CMK CTRP2 0.774 2.1287 0.7738 35.113
AMO1 GDSC1; GDSC2; CTRP2 0.7902 4.5212 0.6429 38.0657
KHM-1B CTRP2 0.8099 3.3686 0.7842 43.663
Jiyoye GDSC1; GDSC2 0.8222 3.3252 0.593 26.2768
KMOE-2 GDSC1; GDSC2 0.8314 2.7942 0.7277 25.5258
TF-1 CTRP2 0.8533 2.5677 0.8512 34.5908
GDM-1 GDSC1; GDSC2 0.8706 4.255 0.3444 27.3467
PL21 CTRP2 0.9171 3.2715 0.8994 34.2172
KG-1 GDSC1; GDSC2 0.9335 2.029 0.9253 24.0091
WSU-DLCL2 GDSC1; CTRP2 0.9451 2.729 0.9421 33.9823
NCI-H929 GDSC2; CTRP2 0.9736 2.5171 0.9693 34.8486
RPMI-8866 GDSC1; GDSC2 0.9798 4.2719 0.4555 26.2704
ROS-50 GDSC1; GDSC2 1.0089 5.0313 0.1885 27.5064
SU-DHL-10 GDSC2; CTRP2 1.0291 3.1621 1.018 35.928
Ku812 GDSC1; GDSC2; CTRP2 1.0297 3.5207 1.0028 39.6212
JJN-3 GDSC1; GDSC2; CTRP2 1.0378 2.8783 1.0336 33.3686
IM-9 GDSC1; GDSC2 1.0568 3.5554 0.7825 24.1768
TK [Human B-cell lymphoma] GDSC1; GDSC2 1.1186 3.2696 0.9315 23.0906
U266B1 GDSC1; GDSC2; CTRP2 1.1682 4.3874 1.0667 32.8204
JVM-3 GDSC1; GDSC2; CTRP2 1.2178 3.8514 1.1758 38.196
KM-H2 GDSC1; GDSC2; CTRP2 1.219 5.0778 1.0073 38.7356
MEG-01 GDSC1; GDSC2 1.2233 3.6942 0.9201 22.673
KO52 CTRP2 1.2816 2.7254 1.2807 31.7334
LP-1 GDSC1; GDSC2; CTRP2 1.291 2.6305 1.2905 31.6693
CCRF-CEM GDSC1; GDSC2 1.3156 4.134 0.8672 22.5532
HAL-01 GDSC1; GDSC2 1.3486 5.7167 0.2461 25.7366
MOLT-4 GDSC1; GDSC2 1.3495 5.5041 0.3409 25.2461
JVM-2 GDSC1; GDSC2; CTRP2 1.3892 5.8729 1.0099 37.9444
P32/ISH GDSC1; GDSC2 1.401 2.2537 1.3956 19.3038
Hs 445 GDSC1; GDSC2 1.4042 6.1773 0.0947 26.2602
ME1 GDSC1; GDSC2 1.4727 5.8658 0.3051 24.9156
L-428 GDSC1; GDSC2; CTRP2 1.4984 3.4404 1.4881 30.3204
Ci-1 CTRP2 1.5185 2.8608 1.5178 30.1544
CTB-1 GDSC1; GDSC2 1.519 5.9349 0.3204 24.6454
OCI-Ly10 CTRP2 1.5241 6.1108 1.0929 31.5343
THP-1 GDSC1; GDSC2; CTRP2 1.5631 4.6303 1.4547 30.2183
AML-193 CTRP2 1.5847 2.4859 1.5847 29.7111
SUP-T1 GDSC1; GDSC2; CTRP2 1.6135 4.0005 1.5773 29.6405
DG-75 GDSC1; GDSC2 1.6355 5.2897 0.7282 21.9748
K-562 GDSC1; GDSC2; CTRP2 1.6774 4.8387 1.5453 29.5377
U-937 CTRP2 1.8196 3.302 1.8171 28.1545
NKM-1 GDSC1 1.8214 11.4227 -2.652 32.0499
WSU-NHL GDSC1; GDSC2 1.8566 8.76 -0.6976 28.0159
RC-K8 GDSC1; GDSC2 1.8638 3.9301 1.5312 16.4469
Mono-Mac-6 GDSC1; CTRP2 1.8875 14.5497 -2.0263 37.468
HD-MY-Z CTRP2 1.9424 4.8407 1.8297 27.7092
ME1 CTRP2 1.9652 5.3538 1.7604 27.8723
Pfeiffer CTRP2 2.0137 4.0871 1.9877 26.9405
GR-ST GDSC1; GDSC2 2.1106 8.5928 -0.3804 25.7328
NOMO-1 GDSC1; GDSC2 2.2142 7.3692 0.3144 21.9937
Karpas-1106P GDSC2 2.243 3.5048 2.0899 11.6465
Raji GDSC1; GDSC2 2.2491 6.0019 1.0087 18.0018
EB2 GDSC1; GDSC2 2.4085 6.5881 0.8766 18.1969
U-698-M GDSC1; GDSC2 2.5135 10.01 -0.7176 25.7654
Granta-519 GDSC1; GDSC2; CTRP2 2.5228 4.5883 2.4794 23.6078
KY821 GDSC1; GDSC2 2.7778 3.3383 2.7236 5.7468
Reh GDSC1; GDSC2 2.7969 9.0533 0.0078 21.5422
RS4;11 GDSC1; GDSC2; CTRP2 2.8449 3.8866 2.8438 21.3191
Hs 611.T CTRP2 2.9606 6.2475 2.6213 21.7353
YT GDSC1 2.9794 4.6583 1.6457 3.3689
SUP-T11 CTRP2 2.9795 6.0551 2.6966 21.4067
MN-60 GDSC1; GDSC2 2.9879 6.162 1.6148 11.8026
MHH-CALL-3 CTRP2 3.0875 16.127 -1.6324 33.5947
TUR GDSC1; GDSC2 3.2131 10.571 -0.3937 22.1179
L-1236 GDSC1; GDSC2; CTRP2 3.2957 9.05 1.9058 23.3883
VAL GDSC1; GDSC2 3.8576 16.0719 -2.6123 28.1877
P3HR-1 CTRP2 5.5042 12.8147 2.1992 16.9519
Toledo CTRP2 6.1318 17.3166 0.4809 21.5136
Karpas-620 GDSC2; CTRP2 6.837 9.1727 5.0813 2.7496
REC-1 CTRP2 7.8092 10.2111 5.183 1.3217
KMM-1 CTRP2 8.5126 18.4592 1.7544 13.1616
⏷ Show the Full List of 217 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 1.767 4.687 1.6647 28.8411
TE8 CTRP2 1.8212 5.8294 1.4923 29.2476
TE-8 GDSC1; GDSC2 -0.9238 3.0061 -1.2293 43.4856
TE-1 GDSC1; GDSC2; CTRP2 0.7911 4.4607 0.6531 35.4351
OE33 GDSC2; CTRP2 0.8833 4.0272 0.8077 34.6296
EC-GI-10 GDSC1; GDSC2; CTRP2 1.0016 3.7086 0.9611 33.7292
TE-5 GDSC1; GDSC2; CTRP2 2.2512 7.0649 1.5871 27.5632
KYSE-410 GDSC2; CTRP2 2.3951 5.4851 2.1994 24.9841
OE19 GDSC2; CTRP2 2.4588 5.2473 2.3166 24.3737
KYSE-510 GDSC2; CTRP2 2.5908 6.8488 2.0286 24.9831
OE21 GDSC2; CTRP2 2.7481 6.1187 2.4265 23.0828
TE-9 GDSC1; GDSC2; CTRP2 2.8732 5.5653 2.5146 20.2187
TE-4 GDSC2; CTRP2 3.1249 5.3887 3.0104 19.8422
KYSE-150 CTRP2 3.3475 8.111 2.3607 21.576
TE-14 CTRP2 3.366 4.8244 3.343 17.9212
KYSE-70 GDSC2; CTRP2 3.4512 5.1976 3.3926 17.4749
TE-11 GDSC2; CTRP2 3.6609 6.1795 3.4051 16.7784
COLO 680N GDSC2; CTRP2 3.6855 7.5655 2.9393 18.4524
TE-6 GDSC1; GDSC2; CTRP2 3.7112 5.5477 3.6145 15.8754
KYSE-140 GDSC2; CTRP2 3.9908 7.9454 3.1015 20.0805
TE-15 GDSC1; GDSC2 4.0159 9.7184 0.682 14.3773
TE-10 GDSC1; GDSC2; CTRP2 4.0421 7.6392 2.8397 14.6233
KYSE-180 GDSC2; CTRP2 4.3386 7.3359 3.7208 16.1492
KYSE-270 GDSC2 4.7451 7.1054 2.4432 2.5412
KYSE-30 CTRP2 4.8182 8.4654 3.705 12.485
KYSE-520 GDSC2; CTRP2 5.1352 9.8732 3.3279 13.2827
KYSE-450 GDSC2; CTRP2 5.1835 7.2916 4.6114 7.9213
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.8104 9.4857 3.2117 14.5022
Panc 05.04 CTRP2 1.1161 3.4481 1.0959 32.9
Panc 08.13 GDSC2; CTRP2 1.7949 4.4823 1.7214 28.5579
HuP-T4 GDSC2; CTRP2 1.8635 4.4011 1.8032 28.0565
PK-59 CTRP2 2.037 4.7182 1.9488 26.9957
DAN-G GDSC2; CTRP2 2.237 4.3158 2.2038 25.4769
MZ-PC-1 GDSC1; GDSC2 2.3196 8.6563 -0.2206 24.2589
MIA PaCa-2 GDSC2; CTRP2 2.517 4.1301 2.505 23.5401
TCC-Pan2 CTRP2 2.7331 3.5324 2.7331 22.0603
BxPC-3 GDSC2; CTRP2 2.7377 5.3079 2.6068 22.4776
KP-3 GDSC2; CTRP2 2.7813 5.5984 2.5944 26.4757
PL4 GDSC2 2.7919 5.7656 1.6344 12.3195
L3.3 CTRP2 2.962 4.9431 2.9048 20.729
PSN1 GDSC1; GDSC2; CTRP2 3.0763 9.5339 1.4679 25.5327
QGP-1 GDSC2; CTRP2 3.0829 9.2181 1.6136 25.0138
Panc 04.03 CTRP2 3.1393 6.4333 2.7599 20.6947
PaTu 8902 GDSC2; CTRP2 3.1669 5.418 3.0503 19.5695
SNU-213 CTRP2 3.6456 8.8515 2.3515 20.7964
SU.86.86 GDSC2; CTRP2 3.6675 4.3586 3.6671 15.8366
SW1990 CTRP2 3.7238 8.9357 2.3938 20.4284
AsPC-1 GDSC2; CTRP2 3.903 7.6699 3.1258 17.14
Capan-1 GDSC2; CTRP2 3.9849 6.0724 3.7891 14.4062
HPAC GDSC2; CTRP2 4.2199 6.1212 4.0317 12.816
PK-45H CTRP2 4.2675 8.3879 3.1911 15.9203
Hs 766T CTRP2 4.3103 7.0069 3.8235 13.3338
Panc 03.27 CTRP2 4.5744 8.7563 3.3291 14.598
CFPAC-1 GDSC2; CTRP2 4.642 6.3847 4.4091 10.1756
KP-1N GDSC2 4.7021 7.1258 2.4098 2.7856
Panc 10.05 GDSC2; CTRP2 4.7367 7.6455 3.9998 11.5038
Panc 02.03 GDSC2; CTRP2 4.739 9.1998 3.2802 14.3949
KP-2 GDSC2; CTRP2 4.7986 7.9556 3.9222 11.657
SNU-410 CTRP2 4.8882 12.7461 1.6872 20.1859
HPAF-II GDSC2; CTRP2 5.0959 7.9892 4.2009 11.5897
PaTu 8988s CTRP2 5.1663 8.6055 3.9745 10.5566
HuP-T3 GDSC2; CTRP2 5.1721 12.2582 2.1837 17.7276
KP-4 GDSC2; CTRP2 5.3567 7.4426 4.7134 7.0807
PaTu 8988t GDSC2; CTRP2 6.0448 7.4196 5.3571 2.8882
SUIT-2 GDSC2; CTRP2 6.0845 9.2682 4.4658 6.5581
YAPC GDSC2; CTRP2 6.2832 9.4344 4.544 5.8604
Capan-2 GDSC2; CTRP2 8.3424 14.4728 3.557 6.7254
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACM5.1 C GDSC2 0.4975 5.1329 -0.3918 32.5667
ESO-26 GDSC2 2.2679 3.8977 1.9756 12.187
KYSE-220 GDSC2 2.3734 7.4958 0.4 20.972
KYAE-1 GDSC2 2.5276 4.8778 1.8124 12.1468
ESO-51 GDSC2 2.7077 4.1012 2.3494 8.2119
TE-12 GDSC1; GDSC2 2.7863 6.5356 1.2495 14.6986
HCE-4 GDSC2 2.8628 5.6276 1.7672 11.2587
FLO-1 GDSC2 3.3685 5.5126 2.2652 6.5565
OACP4 C GDSC2 3.4387 6.6185 1.7699 9.4785
KYSE-50 GDSC2 4.4759 6.8989 2.3792 3.3302
SK-GT-4 GDSC2 4.5046 9.7407 1.0369 11.1494
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 4.4321 8.0833 3.4946 14.2954
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 GDSC2; CTRP2 -1.6757 1.2325 -1.6834 51.4224
SJNB-12 GDSC1 -1.5395 3.6423 -2.3144 48.8051
CHP-126 GDSC1; GDSC2; CTRP2 -0.7064 1.5937 -0.7097 44.9832
SJNB-14 GDSC1; GDSC2 -0.6047 1.6874 -0.652 39.6123
KP-N-RT-BM-1 GDSC2 -0.4032 3.2499 -0.7239 38.6819
SK-N-BE(2) CTRP2 -0.3059 5.3192 -0.7021 43.1077
SJNB-13 GDSC1; GDSC2 -0.2778 2.2286 -0.3711 36.5583
SK-N-MC-IXC GDSC2 -0.0133 2.0205 -0.0624 33.7118
SJNB-17 GDSC1; GDSC2 0.3294 3.4988 0.0061 31.6288
TGW GDSC1; GDSC2 0.3401 2.4867 0.2518 30.3682
NB69 GDSC1; GDSC2 0.4468 1.5482 0.4436 28.8679
MHH-NB-11 GDSC1; GDSC2; CTRP2 0.4606 4.128 0.3469 37.546
NB(TU)1 GDSC1; GDSC2 0.4645 2.8305 0.3227 29.3949
NH-6 CTRP2 0.4981 3.3895 0.4597 37.0725
GOTO GDSC1; GDSC2 0.5375 5.4003 -0.4585 32.6473
SK-N-DZ GDSC1; GDSC2; CTRP2 0.7589 2.6102 0.7557 35.2235
Kelly GDSC1; GDSC2; CTRP2 0.7981 3.67 0.7517 35.1025
SiMa GDSC1; GDSC2; CTRP2 0.9933 3.4025 0.9716 33.723
SK-N-BE(2)-M17 GDSC1; GDSC2 1.01 3.3558 0.7895 24.3559
NB1 GDSC1; CTRP2 1.0832 2.6533 1.0818 33.0571
SJNB-6 GDSC1; GDSC2 1.1577 3.1008 1.0166 22.4534
IMR-32 CTRP2 1.1696 2.4126 1.1694 32.4771
LA-N-6 GDSC1; GDSC2 1.172 4.5068 0.5718 24.7939
SJNB-10 GDSC1; GDSC2 1.2336 4.8719 0.4902 24.9596
SJNB-5 GDSC1; GDSC2 1.5227 3.3181 1.3594 18.9156
SK-N-FI GDSC1; CTRP2 1.7232 3.6722 1.7097 28.8337
KP-N-YS GDSC1; GDSC2 1.8321 6.3958 0.4173 22.8864
CHP-134 GDSC2 1.9777 4.884 1.2574 17.5703
KP-N-YN GDSC1; GDSC2; CTRP2 2.1994 10.6229 0.0901 32.2449
SK-N-SH CTRP2 2.3355 5.7547 2.0721 25.6163
SK-N-AS GDSC2; CTRP2 2.6749 5.921 2.4001 23.4023
SJNB-7 GDSC1; GDSC2 2.8352 9.3723 -0.1179 22.027
IMR-5 GDSC1; GDSC2 2.8635 5.4195 1.8703 10.6137
NH-12 GDSC1; GDSC2 2.8892 4.3216 2.4277 7.0596
GI-ME-N GDSC1; GDSC2 2.9174 10.8055 -0.7621 24.63
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -1.3819 2.0899 -1.4104 49.4844
HuH-28 CTRP2 1.5203 3.5132 1.4837 32.1734
SNU-245 CTRP2 1.7487 4.6494 1.6505 28.9489
SNU-869 CTRP2 2.8359 6.5478 2.3934 22.9353
HuCC-T1 GDSC2; CTRP2 3.0652 8.4199 1.9366 23.9226
SNU-308 CTRP2 3.7792 7.6961 2.5582 17.899
SNU-1196 CTRP2 4.1744 6.6594 3.8079 13.7776
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC1; GDSC2; CTRP2 -0.8206 2.3097 -0.8435 45.6776
HCC1599 GDSC1; GDSC2 -0.8078 2.7074 -1.0332 34.3848
MDA-MB-361 GDSC2; CTRP2 -0.1643 2.39 -0.1754 41.3024
MDA-MB-330 GDSC2 -0.1157 2.5097 -0.2432 35.1032
Evsa-T GDSC1; GDSC2 -0.113 2.5421 -0.2462 28.4259
CAL-148 GDSC1; GDSC2 -0.0551 2.5272 -0.331 22.2797
HCC2157 GDSC1; GDSC2 0.1795 2.0886 0.134 31.7627
MDA-MB-453 GDSC2; CTRP2 0.5859 2.2923 0.5845 36.2874
HCC2218 GDSC1; GDSC2; CTRP2 0.8541 3.1283 0.8404 34.5449
HCC1428 GDSC2; CTRP2 1.0616 3.3272 1.0453 33.1748
AU565 GDSC2; CTRP2 1.1195 2.9636 1.1148 32.7514
SK-BR-3 CTRP2 1.4036 2.8792 1.4023 30.922
EFM-192A GDSC2 1.4454 6.3368 0.0628 21.5321
Hs 578T GDSC2; CTRP2 1.5469 3.604 1.5316 29.9458
HCC1500 GDSC1; GDSC2; CTRP2 1.7041 5.0157 1.5437 29.3888
MCF-7 GDSC2; CTRP2 1.73 5.2606 1.5245 29.3692
UACC-893 GDSC2 1.8382 4.7847 1.1573 15.1479
BT-474 GDSC1; GDSC2; CTRP2 1.9062 5.5115 1.6618 28.3351
BT-483 GDSC2 2.0083 4.1376 0.1706 2.9319
MDA-MB-175-VII GDSC2 2.0805 5.5238 -0.4371 6.3598
MDA-MB-231 GDSC2; CTRP2 2.1164 4.8345 2.0172 26.4446
CAL-85-1 GDSC2; CTRP2 2.1889 4.8316 2.0951 25.9446
HCC202 CTRP2 2.2427 4.8232 2.1539 25.6284
HCC1954 GDSC2; CTRP2 2.2766 5.2586 2.1173 25.5871
CAMA-1 GDSC2; CTRP2 2.3167 4.9397 2.2159 25.1193
HCC1806 GDSC2; CTRP2 2.5998 5.0049 2.5095 23.2024
MRK-nu-1 GDSC1; GDSC2 2.6328 9.2426 -0.2307 19.3733
OCUB-M GDSC1; GDSC2 2.6668 11.0943 -1.1229 22.8957
MDA-MB-468 GDSC2; CTRP2 2.6841 5.6868 2.4683 23.0795
HCC70 GDSC2 2.7328 9.6265 -0.3338 19.5539
HCC1569 GDSC2; CTRP2 2.7838 6.3478 2.1301 18.6484
HCC1143 GDSC2; CTRP2 2.9198 7.0758 2.306 22.9511
T-47D GDSC2; CTRP2 3.1003 5.7209 2.9137 20.2136
BT-549 GDSC2; CTRP2 3.1302 7.8791 2.2262 22.6347
MDA-MB-157 GDSC2; CTRP2 3.2064 6.1557 2.9161 19.8801
JIMT-1 GDSC2; CTRP2 3.2277 4.6306 3.2124 18.7737
HCC1419 GDSC2 3.2696 4.8672 2.5053 4.3061
CAL-51 GDSC2; CTRP2 3.4775 6.9584 2.9493 18.9592
HMC-1-8 CTRP2 3.5222 4.8738 3.5021 21.0846
BT-20 GDSC2; CTRP2 3.5323 5.417 3.4451 16.9951
HCC38 GDSC2; CTRP2 3.575 6.7849 3.1162 18.0563
MFM-223 GDSC1; GDSC2 3.9045 5.4941 2.6745 2.1694
ZR-75-30 GDSC2; CTRP2 3.9677 8.7241 2.7362 18.4349
UACC-812 GDSC1 4.0611 11.1103 -0.7207 16.5008
YMB-1-E GDSC2 4.1072 11.6483 -0.2063 18.6872
MDA-MB-436 GDSC2 4.4201 6.8385 2.3728 2.8037
ZR-75-1 CTRP2 4.5193 7.548 3.8194 12.7842
HCC1187 GDSC1; GDSC2 4.6488 15.3544 -1.6275 20.0584
CAL-120 GDSC2; CTRP2 4.8813 7.2542 4.3202 9.8353
MDA-MB-415 GDSC2 4.8867 9.5871 1.3779 6.7944
HCC1395 GDSC2; CTRP2 5.0298 9.6772 2.7158 10.4712
EFM-19 GDSC2 5.2239 7.8542 2.3758 1.805
HDQ-P1 GDSC2; CTRP2 5.243 10.46 3.1377 13.7872
COLO 824 GDSC1; GDSC2 5.2533 11.5553 0.6824 9.4313
HCC1937 GDSC2; CTRP2 5.4131 11.2443 2.2461 11.7485
Hs 578Bst CTRP2 6.9474 9.7157 4.8958 3.3381
KPL-1 CTRP2 6.9832 7.5922 5.8476 0.0614
BT 145 CTRP2 1.4785 5.6309 1.168 31.4453
BT 428 CTRP2 1.6065 4.6354 1.5005 29.9214
BT 239 CTRP2 2.0954 4.7599 2.0054 26.6134
BT 231 CTRP2 2.5877 7.6765 1.7278 26.053
BT164 CTRP2 2.8496 6.1679 2.5233 22.4255
BT 245 CTRP2 2.8869 7.2931 2.1919 23.5139
BT 416 CTRP2 3.4372 5.6657 3.2928 17.8675
BT 216 CTRP2 3.4971 7.0614 2.9329 19.0073
BT 112 CTRP2 3.7806 8.6094 2.5965 19.5068
BT 131 CTRP2 4.1225 9.4546 2.5573 18.7709
BT 159 CTRP2 4.1937 8.888 2.8897 17.2959
BT 330 CTRP2 4.5382 13.4626 1.0158 23.2794
BT 179 CTRP2 4.5673 7.0316 4.086 11.6145
BT 333 CTRP2 4.5837 9.7365 2.8743 16.3927
BT 224 CTRP2 4.6237 8.5039 3.4952 13.8094
BT 187 CTRP2 4.7083 7.5181 4.0271 11.469
BT 320 CTRP2 5.0627 9.7149 3.3382 13.4046
BT 228 CTRP2 5.1119 6.9812 4.6765 7.8462
BT 139 CTRP2 5.4024 7.3113 4.8199 6.5366
BT147 CTRP2 5.4713 13.5457 1.8061 18.4764
BT 286 CTRP2 5.6709 11.8857 2.807 14.2401
BT 504 CTRP2 5.7993 10.2769 3.7206 10.2415
BT 232 CTRP2 5.8278 11.6063 3.081 12.8177
BT 248 CTRP2 5.9893 9.1846 4.4282 6.9002
BT 271 CTRP2 6.0478 12.6708 2.734 13.7708
BT 359 CTRP2 6.0928 12.7313 2.7412 13.654
BT 172 CTRP2 6.2108 12.9431 2.7327 13.4587
BT 482 CTRP2 6.4535 17.5612 0.6232 20.4514
BT 498 CTRP2 6.5484 11.4282 3.7601 8.6583
BT 340 CTRP2 6.7939 10.1852 4.5605 4.9306
BT 422 CTRP2 7.0913 11.7578 4.0063 6.738
BT 444 CTRP2 7.5172 16.7747 1.8517 14.4211
BT 440 CTRP2 7.8044 16.1975 2.3495 12.1327
BT 328 CTRP2 11.6287 26.2957 0.1087 14.0176
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.0084 5.133 2.7976 19.5002
Cancer Drug Sensitivity Data Curated from 66 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 0.4604 5.3649 -0.525 33.2909
Onda 10 GDSC1; GDSC2 0.9464 6.4559 -0.4932 30.8934
D283 Med GDSC1; GDSC2; CTRP2 1.0571 2.3727 1.0568 33.2272
PFSK-1 GDSC2 1.0697 3.9395 0.6714 24.7157
Daoy GDSC2; CTRP2 1.263 3.3161 1.2518 37.7287
D-542MG GDSC1; GDSC2 1.3698 5.4232 0.3973 24.8661
KINGS-1 GDSC1; GDSC2 1.4314 6.7175 -0.1272 27.2097
GI-1 GDSC1; GDSC2 1.4702 4.8247 0.7577 22.4957
SNU-466 CTRP2 1.5938 2.7982 1.5918 31.3494
AM-38 GDSC1; GDSC2; CTRP2 1.6482 3.0904 1.6466 29.2937
D-566MG GDSC2 1.6763 3.8396 1.3621 18.2138
D-423MG GDSC2 2.0209 5.3347 1.0979 18.3364
SF268 GDSC1; GDSC2; CTRP2 2.0864 4.7944 1.9908 26.6922
DK-MG GDSC2; CTRP2 2.2845 6.1749 1.9048 26.361
SF295 GDSC2; CTRP2 2.3151 5.1861 2.026 24.6457
SF126 GDSC1; GDSC2; CTRP2 2.3534 4.6237 2.2969 29.3161
SNU-201 CTRP2 2.3697 5.9465 2.0604 25.5501
GB-1 GDSC1; GDSC2; CTRP2 2.4447 6.2952 2.0447 29.9611
U-87MG ATCC GDSC1; GDSC2; CTRP2 2.5653 6.7269 2.0415 25.0147
U-118MG GDSC2; CTRP2 2.6439 6.0094 2.3428 23.7015
SNU-1105 CTRP2 2.708 4.6878 2.6646 22.3738
A-172 GDSC2; CTRP2 2.7153 4.1872 2.7061 22.2098
M059K CTRP2 2.8084 5.7479 2.5892 22.3173
D-502MG GDSC1; GDSC2 2.8499 6.0258 1.559 12.5944
KNS-60 CTRP2 2.915 3.684 2.9149 20.8487
Hs 683 GDSC2; CTRP2 2.9559 5.5946 2.7851 21.1648
D-247MG GDSC1; GDSC2 3.0151 14.7367 -2.6431 30.5585
42-MG-BA GDSC2; CTRP2 3.0347 4.3948 3.0252 20.0825
GMS-10 CTRP2 3.0782 5.6936 2.8959 20.3912
D-263MG GDSC1; GDSC2 3.1072 8.0691 0.7671 16.5106
8-MG-BA GDSC1; GDSC2; CTRP2 3.1563 5.6733 2.9855 19.8309
U-251MG GDSC2; CTRP2 3.2388 5.322 3.1452 19.0106
H4 GDSC2 3.2554 5.2061 2.3239 6.5152
ONS-76 GDSC1; GDSC2; CTRP2 3.2604 6.4934 2.8727 19.9212
D-336MG GDSC1; GDSC2 3.3088 5.6513 2.1463 7.4804
YH-13 GDSC2; CTRP2 3.352 5.9419 3.1335 18.6983
SK-MG-1 GDSC2 3.3582 5.3712 2.3274 6.1923
TM-31 CTRP2 3.4184 7.456 2.6992 20.109
KG-1-C CTRP2 3.4313 5.2213 3.368 17.6238
KNS-81-FD GDSC1; GDSC2 3.5071 6.0016 2.1331 7.0042
Becker GDSC1; GDSC2; CTRP2 3.5259 6.2853 3.2265 17.835
LN-18 GDSC2; CTRP2 3.6065 5.0251 3.4804 12.8689
SNU-489 CTRP2 3.6879 7.9269 2.7937 19.002
CAS-1 GDSC1; GDSC2; CTRP2 3.6895 10.6043 1.5936 23.4391
KALS-1 GDSC1; GDSC2; CTRP2 3.7198 9.3364 2.2094 21.132
SNU-738 CTRP2 3.7505 5.9634 3.5626 15.9374
LN-405 GDSC2 3.8206 7.4171 1.6736 9.0457
GaMG GDSC2; CTRP2 3.8441 5.6088 3.7465 14.994
D-392MG GDSC1; GDSC2 4.1349 6.2494 2.4676 3.452
D-245MG GDSC2 4.2143 10.6044 0.395 15.404
DBTRG-05MG GDSC2; CTRP2 4.2177 6.6926 3.8427 13.5224
SF539 GDSC1; GDSC2; CTRP2 4.2208 10.8239 2.0052 20.6124
LN-229 GDSC2; CTRP2 4.2221 5.5163 3.9852 8.1502
SW1088 GDSC2; CTRP2 4.2289 6.2631 3.9993 12.9075
YKG-1 GDSC2; CTRP2 4.4435 7.3274 3.8343 12.9278
M059J GDSC2 4.4741 7.6578 2.0227 5.4109
Onda 11 GDSC1; GDSC2 4.4792 15.8055 -1.9836 24.7159
NMC-G1 GDSC1; GDSC2; CTRP2 4.6229 7.174 4.086 11.4633
SNU-626 CTRP2 4.7662 9.1307 3.3394 14.0908
T98G GDSC2; CTRP2 5.1404 7.8934 4.2896 9.3285
GOS-3 CTRP2 5.2152 7.6118 4.4951 8.3119
KNS-81 CTRP2 5.4697 8.8916 4.1174 9.2807
CCF-STTG1 CTRP2 6.2392 10.1169 4.1681 7.5167
KNS-42 GDSC1; GDSC2; CTRP2 6.2431 8.6466 4.905 4.4194
SW1783 CTRP2 6.6181 15.678 1.6969 16.5763
SNB-75 GDSC1; GDSC2; CTRP2 6.7868 12.5836 3.371 9.8385
⏷ Show the Full List of 66 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 1.9918 11.3822 -1.8641 31.5784
TGBC24TKB GDSC2 3.4325 6.4557 1.8462 9.018
TGBC1TKB GDSC1 8.1256 23.6294 -3.9702 20.4571
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-6 CTRP2 0.2068 3.1134 0.1751 48.6349
ESS-1 GDSC2; CTRP2 0.7691 3.614 0.7258 35.2854
JHUEM-2 CTRP2 1.2853 6.0247 0.856 40.8895
JHUEM-7 CTRP2 1.43 5.5957 1.1236 31.7513
RL95-2 GDSC1; GDSC2; CTRP2 1.8507 5.1644 1.6744 28.5356
HEC-59 CTRP2 2.1624 5.432 1.958 33.1502
MFE-319 GDSC2; CTRP2 2.2116 4.0776 2.1932 25.5963
HEC-151 CTRP2 2.3021 5.7119 2.0461 25.8122
JHUEM-3 CTRP2 2.4431 7.7694 1.5379 27.1424
JHUEM-1 CTRP2 3.173 5.2816 3.0813 19.4424
EFE-184 CTRP2 3.4781 9.154 2.0464 22.3798
AN3-CA GDSC2; CTRP2 3.6449 7.7148 2.836 18.9586
HEC-1-B CTRP2 3.6887 6.451 3.352 16.89
HEC-1-A CTRP2 3.8485 8.0264 2.9192 18.0844
KLE GDSC2; CTRP2 3.8564 7.3081 2.8163 15.3212
EN GDSC2; CTRP2 3.8908 7.4903 3.1865 16.9398
HEC-265 CTRP2 3.8983 6.0883 3.6902 18.7798
HEC-108 CTRP2 4.1867 7.5802 3.4601 18.8272
MFE-280 GDSC2 4.3027 9.0695 1.2189 10.581
HEC-251 CTRP2 5.2638 8.8597 3.943 13.0645
MFE-296 GDSC2; CTRP2 5.5398 9.912 3.6756 10.9667
HEC-50B CTRP2 5.9818 9.3937 4.3173 7.9266
Ishikawa (Heraklio) 02 ER- CTRP2 3.3405 5.163 3.2792 22.7732
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB2241-RCC GDSC1; GDSC2 0.7325 5.1124 -0.1355 30.3222
LB996-RCC GDSC1; GDSC2 1.2865 8.0866 -0.914 31.082
LB1047-RCC GDSC1; GDSC2 1.2955 8.2429 -0.9798 31.2854
BB65-RCC GDSC1; GDSC2 1.4287 6.1962 0.1107 26.0798
TK-10 GDSC1; GDSC2 1.5977 8.9831 -1.0485 30.3416
SNU-1272 CTRP2 1.6006 8.237 0.1073 36.736
KTCTL-140 GDSC2 2.1124 5.9573 0.8977 19.1519
Caki-1 GDSC2; CTRP2 2.333 7.6389 1.4692 27.7106
KTCTL-21 GDSC2 2.3361 6.4126 0.8939 18.3547
SW156 GDSC2 2.4969 7.2682 0.6251 19.3134
KTCTL-13 GDSC2 2.5601 5.7435 1.4295 14.3721
A-498 GDSC2; CTRP2 2.5602 4.1998 2.5463 23.2587
SW13 GDSC2 2.6349 4.653 2.0231 10.4657
TUHR10TKB CTRP2 2.6724 3.1951 2.6724 22.4644
KTCTL-1M GDSC2 2.795 5.1384 1.9443 10.3839
UO-31 GDSC2; CTRP2 2.8962 6.4257 2.4975 22.3774
VMRC-RCZ GDSC2; CTRP2 3.0687 5.9046 2.834 20.641
RXF 393L GDSC1; GDSC2 3.0689 6.1351 1.6993 11.0206
ACHN GDSC2; CTRP2 3.1112 5.9322 2.8732 20.3702
KTCTL-26A GDSC2 3.1359 6.5057 1.5725 11.6033
NCC021 GDSC2 3.2504 5.9454 1.9501 8.8921
CAL-54 GDSC2; CTRP2 3.4202 6.0822 3.1701 18.3582
KTCTL-195 GDSC2 3.4385 6.494 1.832 9.0902
786-O GDSC2; CTRP2 3.4963 6.9788 2.9622 18.8997
HA7-RCC GDSC1; GDSC2 3.6315 9.096 0.6886 15.3966
TUHR4TKB CTRP2 3.6922 7.3569 3.0292 18.0916
769-P GDSC2; CTRP2 3.7595 6.3654 3.4563 19.2785
A-704 GDSC2 3.8376 8.5792 1.1097 12.4093
NCC010 GDSC2 3.9371 8.2533 1.3483 10.7277
TUHR14TKB CTRP2 4.103 7.7613 3.2965 15.9385
VMRC-RCW GDSC2; CTRP2 4.1203 6.7618 3.7127 14.291
KMRC-20 GDSC2; CTRP2 4.2896 7.5396 3.5846 14.315
OS-RC-2 GDSC1; GDSC2; CTRP2 4.4552 11.3741 1.9618 20.2024
KMRC-1 CTRP2 4.5708 7.3953 3.9384 12.1802
RCC10RGB GDSC1; GDSC2; CTRP2 4.9121 7.3786 4.2972 9.8686
KMRC-3 CTRP2 4.97 8.4127 3.8781 11.4146
BFTC-909 GDSC2; CTRP2 5.0169 9.7468 3.28 13.7462
Caki-2 CTRP2 5.3247 5.9546 5.2815 4.9441
KMRC-2 CTRP2 5.5312 10.0126 3.6179 11.224
SN12C GDSC2 5.7523 7.7909 2.6456 0.6547
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 58 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2998 GDSC1; GDSC2 0.0413 2.2248 -0.0293 33.27
LoVo GDSC2; CTRP2 0.1465 5.0906 -0.159 40.0859
RCM-1 [Human ESC] GDSC2; CTRP2 0.6391 2.5541 0.6356 36.0226
SW948 GDSC2; CTRP2 0.7116 2.6618 0.7072 35.5426
SNU-C1 GDSC1; GDSC2; CTRP2 0.717 2.9478 0.7064 35.5266
OUMS-23 CTRP2 1.3332 2.734 1.3324 31.3895
SK-CO-1 GDSC2; CTRP2 1.4016 3.5024 1.3868 30.9804
LS180 GDSC2; CTRP2 1.4209 3.1274 1.4169 36.4568
CCK-81 GDSC2 1.5076 3.5774 1.2666 19.4917
SNU-283 GDSC2 1.539 3.6876 1.2653 19.3583
MDST8 GDSC1; GDSC2; CTRP2 1.546 2.7283 1.5457 29.97
GP2d CTRP2 1.5908 4.4508 1.5084 29.9469
COLO 320HSR GDSC1; GDSC2 1.6437 5.6513 0.5747 22.7859
HT115 GDSC2; CTRP2 1.7552 3.378 1.7382 28.2162
DiFi GDSC2 1.8816 3.5066 1.6961 15.4428
HCC-56 CTRP2 1.9162 3.5737 1.9099 27.5239
NCI-H747 GDSC1; GDSC2; CTRP2 1.9564 4.5109 1.8893 27.4608
HCT 8 CTRP2 1.989 4.1964 1.9541 27.1348
SW1417 GDSC2; CTRP2 2.0793 4.1952 2.0484 26.5199
LS513 GDSC1; GDSC2; CTRP2 2.0806 4.395 2.0328 26.5684
SNU-503 CTRP2 2.1614 5.928 1.838 26.98
NCI-H716 GDSC1; GDSC2; CTRP2 2.1623 4.32 2.1253 25.9877
SNU-61 GDSC2; CTRP2 2.1756 6.1713 1.787 27.1115
SNU-175 GDSC2 2.1981 4.7536 1.54 15.035
CW-2 GDSC1; GDSC2; CTRP2 2.2747 5.9162 1.9647 28.1111
NCI-H508 GDSC2; CTRP2 2.2789 4.1241 2.2601 25.1493
SW48 GDSC2; CTRP2 2.2912 4.2875 2.2625 25.1005
SNU-C5 GDSC2; CTRP2 2.3656 5.5898 2.144 25.2704
COLO 320 CTRP2 2.367 5.668 2.1273 25.3241
LS411N GDSC1; GDSC2; CTRP2 2.378 3.6689 2.3758 24.4334
HT-55 GDSC2; CTRP2 2.413 4.2407 2.3921 24.2629
HCT 116 GDSC2; CTRP2 2.6972 4.9012 2.6283 26.6571
KM12 GDSC1; GDSC2; CTRP2 2.716 6.7584 2.1946 24.0122
COLO205 GDSC2; CTRP2 2.8244 4.8897 2.7652 21.6523
SNU-1033 CTRP2 2.8561 4.0194 2.8535 21.2495
CaR-1 GDSC2 2.9227 5.554 1.858 10.4948
SNU-C2A CTRP2 2.9874 6.3952 2.6062 27.0973
CL-11 GDSC1; GDSC2; CTRP2 2.9923 4.243 2.987 20.3514
SW626 GDSC2 3.0429 6.9707 1.2601 13.8096
HCT 15 GDSC2; CTRP2 3.0982 5.5876 2.9413 20.1686
LS123 GDSC1; GDSC2; CTRP2 3.1982 5.5642 3.055 19.4546
SW1116 GDSC2 3.2542 5.4055 2.2232 7.1558
GP5d GDSC2 3.2653 5.5583 2.1562 7.5462
DLD-1 CTRP2 3.3425 7.1004 2.7524 20.126
SW1463 GDSC2 3.3814 5.6752 2.1945 6.9668
SNU-C2B GDSC2 3.4315 7.5733 1.2868 12.4803
SW620 GDSC2; CTRP2 3.4999 6.2012 3.2232 17.9248
SNU-81 GDSC2 3.5066 6.2 2.0337 7.6317
C2BBe1 GDSC1; GDSC2; CTRP2 3.6604 6.8815 3.1741 17.6345
COLO 678 GDSC2; CTRP2 3.7359 6.5389 3.3746 16.6676
SW837 GDSC2 3.8121 5.9584 2.3865 4.6401
LS1034 GDSC1; GDSC2; CTRP2 3.8132 6.0669 3.6032 15.5997
SNU-1040 GDSC2 3.8473 6.2231 2.2825 5.2016
T84 GDSC2; CTRP2 3.9289 5.5261 3.8538 14.3503
SNU-407 GDSC2; CTRP2 3.9736 6.2357 3.7294 14.6575
RKO GDSC1; GDSC2; CTRP2 4.2986 7.9342 3.4242 14.9199
SNU-C4 CTRP2 5.527 9.4365 3.8999 10.0615
HT-29 GDSC2; CTRP2 5.8151 10.3535 3.6959 12.1738
⏷ Show the Full List of 58 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 3.4911 4.7824 2.7274 3.3002
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC2; CTRP2 -1.1995 1.2015 -1.2024 48.2637
SNU-886 CTRP2 0.0173 3.5308 -0.0548 40.3578
JHH-4 GDSC2; CTRP2 1.2289 4.0478 1.1702 32.2764
HuH-6 CTRP2 1.2307 5.9585 0.8142 33.399
JHH-2 GDSC2; CTRP2 1.5586 3.3866 1.5511 29.9101
Li-7 CTRP2 1.6094 5.8133 1.2654 30.6934
SNU-182 CTRP2 1.73 7.1365 0.9982 38.3161
PLC/PRF/5 CTRP2 2.4992 5.1438 2.3789 24.0289
Hep-G2 CTRP2 2.5314 5.5963 2.323 24.1216
SNU-878 CTRP2 2.5564 4.4244 2.5288 23.3303
HLF CTRP2 2.5579 3.141 2.5579 23.2275
HuH-1 GDSC2; CTRP2 2.5986 4.3154 2.5798 23.0195
Hep-G2/C3A GDSC2 2.7903 6.1747 1.4314 13.5768
SNU-423 GDSC2; CTRP2 2.8143 5.1594 2.7155 21.856
JHH-5 CTRP2 3.0632 8.565 1.8736 24.1538
SK-HEP-1 GDSC2; CTRP2 3.4006 5.9601 3.1817 18.3763
HLE GDSC2 3.406 6.2177 1.9435 8.4811
SNU-387 GDSC2; CTRP2 3.4473 8.1999 2.428 21.0477
SNU-398 GDSC2; CTRP2 3.8573 6.4502 3.5356 16.8792
SNU-449 GDSC2; CTRP2 4.079 7.3035 3.4606 15.3678
SNU-761 CTRP2 4.2215 7.1926 3.6558 14.2239
JHH-7 GDSC2 4.6318 7.9389 1.9925 5.2754
Hep 3B2.1-7 GDSC2; CTRP2 4.9974 7.5051 4.3271 9.531
Huh-7 GDSC2 5.0666 6.9403 2.6775 1.0401
JHH-6 GDSC2; CTRP2 5.7054 6.7621 5.3749 3.5449
SNU-475 CTRP2 6.1068 7.0423 5.5964 1.7661
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 214 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H748 GDSC1; GDSC2 -3.0118 -1.178 -3.0126 63.4564
NCI-H1105 GDSC2; CTRP2 -2.6657 0.2085 -2.6691 57.9691
COR-L321 GDSC2 -2.359 -1.3087 -2.3591 57.0086
NCI-H146 GDSC2; CTRP2 -2.2555 -0.9119 -2.2555 55.2949
NCI-H1975 GDSC1; GDSC2 -2.1907 0.42 -2.2135 55.1568
NCI-H1963 GDSC1; GDSC2 -2.141 2.6237 -2.4649 53.9356
COR-L303 GDSC2 -1.9457 -0.3222 -1.9469 52.8546
NCI-H740 GDSC2 -1.7574 0.0626 -1.7609 50.9664
HCC33 GDSC1; GDSC2 -1.65 0.6159 -1.6665 49.8955
COR-L88 GDSC1; CTRP2 -1.6405 2.9368 -1.7421 51.1342
NCI-H187 GDSC1 -1.322 1.0859 -1.3981 45.7784
HCC44 GDSC2; CTRP2 -1.2538 2.8969 -1.3315 56.997
Lu-139 GDSC1; GDSC2 -1.2183 1.4055 -1.2705 45.6998
Lu-134-A GDSC1; GDSC2 -1.0356 1.3887 -1.0773 43.8706
DV-90 CTRP2 -0.858 2.3967 -0.8858 46.0364
NCI-H69 GDSC1 -0.8503 2.4174 -1.1666 41.0249
NCI-H524 GDSC1; GDSC2; CTRP2 -0.7648 2.4738 -0.7935 45.4224
HCC827 GDSC2; CTRP2 -0.7552 3.5326 -0.8714 53.323
NCI-H211 GDSC1; GDSC2; CTRP2 -0.7129 1.4786 -0.7152 53.2483
IST-SL1 GDSC1; GDSC2 -0.6057 2.1801 -0.7153 39.8675
LB647-SCLC GDSC1; GDSC2 -0.5128 4.1371 -1.111 40.5537
Lu-165 GDSC1; GDSC2 -0.3549 3.3764 -0.7057 38.3336
NCI-H250 GDSC2 -0.345 1.6275 -0.3747 36.9403
COR-L32 GDSC2 -0.3161 1.0488 -0.3196 36.5251
CPC-N GDSC1; GDSC2 -0.2893 1.7433 -0.3259 36.415
LC-2/ad GDSC1; GDSC2 -0.2729 4.0788 -0.8312 38.2909
NCI-H1437 GDSC2 -0.238 3.9127 -0.7392 37.7772
NCI-H810 GDSC2; CTRP2 -0.2187 2.6237 -0.239 41.7837
HCC15 GDSC2; CTRP2 -0.2126 3.4877 -0.2927 41.893
NCI-H2171 GDSC1; GDSC2; CTRP2 -0.1856 1.8251 -0.1876 41.5113
DMS 273 GDSC2; CTRP2 -0.0779 4.3356 -0.26 41.2486
NCI-H2106 CTRP2 -0.0376 2.2362 -0.0434 40.5371
NCI-H847 GDSC1 0.01 1.1031 0.0005 28.959
SBC-1 GDSC1; GDSC2 0.051 1.8953 0.0176 32.9905
NCI-H526 GDSC1; GDSC2; CTRP2 0.102 2.8676 0.0533 42.4477
NCI-H2110 GDSC2; CTRP2 0.3227 3.6935 0.2507 38.3375
NCI-H2009 CTRP2 0.3292 2.3587 0.3254 38.0876
NCI-H1341 CTRP2 0.3674 2.2624 0.365 37.829
EMC-BAC-1 GDSC2 0.3939 3.541 0.064 31.0281
NCI-H1876 GDSC1; GDSC2 0.3975 3.113 0.1849 30.418
COR-L95 GDSC1; CTRP2 0.4291 2.741 0.419 37.4428
NCI-H290 GDSC2 0.4291 1.7369 0.42 29.0758
NCI-H82 GDSC1; GDSC2 0.4531 2.5063 0.3701 29.2101
NCI-H209 GDSC1; GDSC2; CTRP2 0.4712 5.3679 0.1327 38.0863
EBC-1 GDSC2; CTRP2 0.5263 3.7609 0.4586 36.975
NCI-H1734 GDSC2; CTRP2 0.542 3.9526 0.38 39.1053
Calu-3 GDSC2; CTRP2 0.5875 6.6358 -0.0823 44.2951
NCI-H1944 GDSC2; CTRP2 0.6182 4.1043 0.5176 36.4652
NCI-H1184 CTRP2 0.6337 3.2127 0.6105 36.1222
COR-L51 CTRP2 0.7101 3.1655 0.6914 35.599
DMS 79 GDSC1; GDSC2; CTRP2 0.716 3.5974 0.6716 42.136
NCI-H510A GDSC1; GDSC2 0.7657 3.142 0.5793 26.6161
NCI-H1623 GDSC2; CTRP2 0.8064 3.8967 0.7401 35.1105
NCI-H446 GDSC1; GDSC2; CTRP2 0.8779 4.0126 0.8035 34.6614
NCI-H2081 GDSC1; GDSC2; CTRP2 0.881 2.9773 0.8725 34.4275
HCC1833 CTRP2 0.9476 2.3115 0.9473 42.4383
NCI-H1915 GDSC2; CTRP2 1.0066 3.085 0.9974 33.593
NCI-H647 GDSC2; CTRP2 1.0756 3.7057 1.0385 33.2258
MOR/CPR CTRP2 1.1119 2.4839 1.1114 41.0715
NCI-H1770 GDSC1; GDSC2 1.1316 4.0817 0.6882 24.3466
NCI-H1693 GDSC2; CTRP2 1.1435 4.9652 0.9472 33.2881
IA-LM GDSC2; CTRP2 1.1918 5.0021 0.9925 32.9788
HCC2108 CTRP2 1.2136 4.1289 1.1457 40.4596
IST-SL2 GDSC1; GDSC2 1.2207 4.288 0.7078 23.8447
NCI-H1092 GDSC1; GDSC2; CTRP2 1.2301 4.1292 1.1632 32.2953
COR-L47 CTRP2 1.2447 3.0306 1.2403 31.9909
NCI-H2227 GDSC1; GDSC2 1.2449 3.7353 0.9302 22.5207
HCC78 GDSC2; CTRP2 1.251 4.2911 1.167 32.2128
VMRC-LCD GDSC2; CTRP2 1.2536 4.3569 1.1616 32.2219
COR-L311 GDSC2 1.3056 3.8194 0.9679 22.0419
NCI-H345 GDSC1; GDSC2 1.3369 5.2651 0.432 24.823
NCI-H1869 GDSC1; GDSC2; CTRP2 1.3545 4.6289 1.2316 31.6528
NCI-H64 GDSC1 1.3795 4.5779 0.3369 19.2971
LXF 289 GDSC1; GDSC2; CTRP2 1.4092 5.2837 1.1714 31.6662
NCI-H1694 GDSC1; GDSC2; CTRP2 1.4449 3.362 1.4359 30.6725
NCI-H2029 GDSC2; CTRP2 1.4466 2.8215 1.4458 30.6338
NCI-H2126 CTRP2 1.4598 3.0933 1.4567 30.5538
NCI-H1304 GDSC1 1.4908 3.7032 0.8572 14.9519
NCI-H1436 GDSC1; GDSC2 1.4994 3.96 1.1283 20.2968
Ms-1 GDSC1; GDSC2 1.514 4.5751 0.9068 21.4789
DMS 53 GDSC2; CTRP2 1.5715 3.6898 1.553 29.8609
NCI-H1648 GDSC1 1.5853 3.2325 1.1663 12.1869
LUDLU-1 CTRP2 1.586 3.5666 1.5733 29.7449
COLO 699 CTRP2 1.5867 5.2481 1.3716 37.8921
UMC-11 GDSC2 1.5917 3.9608 1.2274 19.3393
SHP-77 GDSC1; GDSC2; CTRP2 1.6037 4.3503 1.5341 29.8179
Lu-65 GDSC1; GDSC2; CTRP2 1.6164 7.0584 0.9015 31.8242
NCI-H2141 GDSC1; GDSC2; CTRP2 1.6725 3.666 1.6579 29.175
NCI-H720 GDSC1; GDSC2 1.6834 6.8534 0.0563 25.3149
NCI-H2122 GDSC2; CTRP2 1.7114 3.9873 1.6803 28.971
COR-L105 GDSC2; CTRP2 1.7728 6.7849 1.1613 30.4945
PC-14 GDSC2; CTRP2 1.8184 4.7752 1.7067 28.5308
NCI-H2373 GDSC2 1.8378 4.1264 1.4287 17.1432
Sq-1 CTRP2 1.845 4.4971 1.7727 28.2204
HOP-92 GDSC2; CTRP2 1.8671 5.6374 1.59 28.7693
NCI-H1339 CTRP2 1.9042 4.5536 1.8288 27.8368
NCI-H3122 GDSC2 1.925 5.9738 0.7066 20.9485
DMS 454 CTRP2 1.9345 7.5914 1.0585 30.2989
NCI-H1155 GDSC1; GDSC2; CTRP2 1.9384 3.631 1.931 27.3796
Lu-135 GDSC2 1.9561 3.4622 1.7908 14.5856
HCC1588 CTRP2 1.997 3.6314 1.9906 33.726
LCLC-97TM1 GDSC2; CTRP2 1.9984 5.0495 1.8553 27.4403
NCI-H838 GDSC2; CTRP2 2.0356 4.8737 1.9246 27.083
NCI-H2803 GDSC2 2.0364 4.1258 1.6398 15.0957
NCI-H358 GDSC2; CTRP2 2.0465 4.1189 2.0197 26.7246
LCLC-103H GDSC2; CTRP2 2.0744 3.2827 2.0736 26.4514
NCI-H2795 GDSC2 2.0791 7.485 0.1317 23.4258
NCI-H23 GDSC1; GDSC2; CTRP2 2.1044 5.8828 1.7876 27.3343
NCI-H2135 GDSC1; GDSC2 2.146 5.818 0.9964 18.4549
NCI-H1836 GDSC1; GDSC2 2.1668 5.3553 1.2336 16.9806
NCI-H292 GDSC2; CTRP2 2.1823 4.1213 2.1159 24.7774
COR-L23 GDSC2 2.2391 5.5042 1.2353 16.7001
COLO 668 GDSC1; GDSC2; CTRP2 2.2512 4.6648 2.1837 25.4988
NCI-H2196 GDSC1; GDSC2; CTRP2 2.3426 6.2313 1.952 26.0148
NCI-H2818 GDSC2 2.3989 7.5532 0.3952 20.9074
NCI-H2810 GDSC2 2.4389 6.37 1.0114 17.3045
RERF-LC-A1 CTRP2 2.4646 5.3027 2.3123 30.4429
NCI-H2087 GDSC2; CTRP2 2.4948 7.5487 1.6763 26.5108
NCI-H841 GDSC2; CTRP2 2.4998 4.1982 2.4842 23.6668
NCI-H2291 GDSC2; CTRP2 2.5104 6.5953 1.742 25.1906
NCI-H196 GDSC2 2.5306 5.4626 1.5372 13.8183
NCI-H520 GDSC2; CTRP2 2.5594 5.7399 2.3197 24.0456
BEN GDSC2; CTRP2 2.5648 4.1493 2.5533 23.2198
LK2 CTRP2 2.5662 4.5866 2.5253 23.31
NCI-H2170 GDSC2; CTRP2 2.5757 5.3445 2.4245 23.627
SBC-3 GDSC2 2.5967 4.5327 2.0413 10.4964
NCI-H650 GDSC2; CTRP2 2.6012 5.6123 2.3953 23.6487
NCI-H2228 GDSC2; CTRP2 2.6096 7.1533 1.9437 25.228
NCI-H522 GDSC2 2.6114 3.8343 2.3646 8.505
NCI-H1435 GDSC2; CTRP2 2.6523 3.4995 2.6521 22.5993
NCI-H1666 GDSC1; GDSC2; CTRP2 2.6608 5.6611 2.4489 23.2733
HCC1195 CTRP2 2.6688 4.5122 2.6393 22.5881
HCC4006 CTRP2 2.7119 6.2191 2.3583 23.4375
RERF-LC-MS GDSC2; CTRP2 2.7486 6.3653 2.3551 23.3372
NCI-H2172 GDSC2 2.7648 8.0334 0.4872 19.165
T3M-10 CTRP2 2.7709 8.6017 1.5528 26.1165
NCI-H2030 GDSC2; CTRP2 2.8742 7.7424 2.0083 28.4942
LC-1/sq GDSC2 2.9261 6.7149 1.2852 14.027
LC-1/sq-SF CTRP2 2.9341 6.7182 2.4447 22.4555
NCI-H1755 GDSC2; CTRP2 2.9623 5.0259 2.8942 20.7643
NCI-H1651 GDSC2; CTRP2 3.0237 6.152 2.7178 21.1956
NCI-H661 GDSC2; CTRP2 3.0776 4.1724 3.075 21.239
HCC366 GDSC2; CTRP2 3.113 5.8071 2.9068 20.2444
EPLC-272H GDSC2; CTRP2 3.1262 8.3673 2.0224 23.4402
SBC-5 GDSC2; CTRP2 3.1342 4.4561 3.1248 22.9746
NCI-H3255 GDSC2 3.1649 6.755 1.4728 12.1315
RERF-LC-Sq1 GDSC2 3.2515 9.338 0.255 18.8535
NCI-H226 GDSC1; GDSC2; CTRP2 3.2669 7.8616 2.3777 21.7384
NCI-H1568 GDSC2; CTRP2 3.2786 5.9246 3.0578 19.1949
RERF-LC-KJ GDSC2 3.2875 7.3428 1.2827 12.9266
Lu-99A GDSC2 3.3026 9.3776 0.2779 18.5793
NCI-H1581 GDSC1; GDSC2; CTRP2 3.3107 4.7646 3.2898 18.2825
ChaGo-K-1 GDSC2; CTRP2 3.3238 6.8043 2.8378 19.863
Lu-99 CTRP2 3.333 7.2336 2.6928 20.3761
NCI-H2444 GDSC2; CTRP2 3.3342 5.062 3.2856 18.2202
A-549 GDSC2; CTRP2 3.3411 6.7129 2.888 19.6268
NCI-H2722 GDSC2 3.429 6.5411 1.8007 9.3133
NCI-H2804 GDSC2 3.4346 6.6972 1.7272 9.7573
NCI-H1355 GDSC1; GDSC2; CTRP2 3.452 9.3688 1.924 22.8957
NCI-H1048 GDSC2 3.4792 5.8809 2.171 6.8416
NCI-H322M GDSC1; GDSC2 3.4952 6.2661 1.9916 7.9282
EMC-BAC-2 GDSC2 3.5181 6.8059 1.7406 9.4395
NCI-H1993 GDSC2 3.5355 7.0605 1.6275 10.0949
SK-MES-1 GDSC2; CTRP2 3.5392 5.8184 3.3687 17.2812
NCI-H1385 CTRP2 3.5772 7.2389 2.9522 18.7069
HCC1438 CTRP2 3.5818 5.129 3.5404 16.5459
NCI-H2369 GDSC2 3.6063 6.2056 2.1097 6.8852
NCI-H2461 GDSC2 3.6492 6.7693 1.8628 8.3198
Calu-6 GDSC1; GDSC2; CTRP2 3.6536 6.5731 3.2738 17.2825
A-427 GDSC2 3.6789 6.5851 1.9775 7.524
NCI-H1793 GDSC2; CTRP2 3.7168 6.4392 3.3864 16.6803
DMS 114 GDSC1; GDSC2; CTRP2 3.7193 5.8002 3.5692 16.0099
NCI-H1781 GDSC2 3.726 9.6713 0.4773 16.2877
SW1271 GDSC2; CTRP2 3.7425 7.0178 3.2125 17.2554
NCI-H1703 CTRP2 3.7982 6.692 3.39 16.4289
NCI-H2591 GDSC2 3.8776 7.4881 1.6819 8.8492
NCI-H2023 GDSC2; CTRP2 3.9001 6.4756 3.5738 15.448
HCC2279 CTRP2 3.9211 5.7058 3.8101 18.1568
NCI-H2731 GDSC2 3.9374 8.6946 1.1297 12.0272
NCI-H2405 GDSC2; CTRP2 3.9399 8.0967 2.9838 17.5896
LOU-NH91 GDSC2; CTRP2 3.9618 6.5485 3.6164 15.1092
ABC-1 GDSC2 4.0598 10.2431 0.4554 15.4913
NCI-H596 GDSC2 4.086 7.8198 1.6736 8.383
NCI-H322 CTRP2 4.0988 7.4123 3.4375 15.4025
HOP-62 GDSC1; GDSC2; CTRP2 4.1611 8.9152 2.8446 17.5556
NCI-H1650 GDSC1; GDSC2; CTRP2 4.2381 6.3889 3.9694 12.9901
NCI-H1373 CTRP2 4.2449 7.8329 3.4129 15.1057
HCC2935 CTRP2 4.2617 6.3837 3.9967 12.8195
NCI-H441 GDSC2 4.2688 9.2665 1.0971 11.3735
NCI-H2085 GDSC2; CTRP2 4.3451 8.3995 3.2643 16.5685
NCI-H513 GDSC2 4.372 9.6004 1.009 11.6276
LK-2 GDSC2 4.3775 9.8362 0.8972 12.2494
NCI-H2342 CTRP2 4.4848 10.3264 2.4965 18.1116
CAL-12T GDSC2; CTRP2 4.556 9.0566 3.1702 18.0311
NCI-H2869 GDSC2 4.6199 7.2868 2.2884 3.593
NCI-H1395 CTRP2 4.6434 10.3869 2.618 17.2604
NCI-H1299 GDSC1; GDSC2; CTRP2 4.6447 8.3253 3.5986 13.3417
NCI-H2595 GDSC2 4.7618 7.3327 2.3514 3.0085
HARA [Human squamous cell lung carcinoma] GDSC2; CTRP2 4.8937 8.8596 3.5917 12.7636
SW1573 GDSC2; CTRP2 4.9485 10.0328 3.0767 14.7264
RERF-LC-Ad1 CTRP2 5.1623 7.0116 4.1573 4.7818
NCI-H460 GDSC2; CTRP2 5.1783 10.4665 3.0757 14.2125
NCI-H1838 GDSC1 5.2515 7.0502 1.7432 0.2817
RERF-LC-Ad2 CTRP2 5.2551 9.1068 3.8142 11.0142
SK-LU-1 GDSC2; CTRP2 5.2744 8.023 4.3578 8.73
NCI-H1563 GDSC2; CTRP2 5.3383 9.487 3.7043 11.2831
HCC1171 CTRP2 5.6262 11.0572 3.1815 15.8919
KNS-62 GDSC2; CTRP2 5.7037 12.3411 2.6078 14.9605
NCI-H727 GDSC2; CTRP2 5.8091 13.9268 1.9055 17.4098
NCI-H1792 GDSC2; CTRP2 6.0941 10.3986 3.9086 8.8761
Calu-1 CTRP2 6.4207 13.1125 2.8189 12.7197
EKVX GDSC1; GDSC2; CTRP2 7.5412 14.6244 2.9289 10.3465
NCI-H128 GDSC1 8.0886 22.2798 -3.3579 18.657
Hs 888.Lu CTRP2 4.008 9.03 2.6386 18.7496
⏷ Show the Full List of 214 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 1.945 5.2349 1.0671 18.8103
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 -2.9943 -1.5044 -2.9943 60.2164
H-STS CTRP2 -2.1567 -1.1167 -2.1567 54.6372
SYO-1 CTRP2 1.5231 4.5001 1.43 30.433
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 2.0959 4.4762 2.0407 26.4913
Aska-SS CTRP2 2.4943 3.6812 2.4928 23.6565
Rh41 GDSC2; CTRP2 -0.254 1.8637 -0.2568 41.9692
STS-0421 GDSC2 0.3448 4.4856 -0.3054 32.9599
SW872 GDSC1; GDSC2 0.89 2.3613 0.8555 24.5797
HT-1080 GDSC2; CTRP2 0.9169 5.8506 0.5003 35.4296
TE 441.T GDSC1; GDSC2; CTRP2 0.9557 4.6765 0.7957 34.4152
MFH-ino GDSC1 1.0239 4.9515 -0.1859 24.5223
G-401 GDSC2; CTRP2 1.4089 5.6619 1.0846 31.9474
GCT GDSC2; CTRP2 1.423 4.1874 1.3606 30.9966
Rh18 CTRP2 1.4439 3.7401 1.4186 30.7336
TTC-709 CTRP2 1.6477 7.7445 0.6942 32.3401
SK-LMS-1 GDSC1; GDSC2; CTRP2 1.9574 6.4547 1.4657 28.8989
Tm87-16 CTRP2 2.0463 6.4386 1.5675 28.2722
Rh30 GDSC2 2.1561 5.0373 1.3693 16.2142
TE 617.T CTRP2 2.3603 4.532 2.3139 24.7001
KYM-1 GDSC1; GDSC2; CTRP2 2.433 4.9939 2.3323 24.4019
RD GDSC2; CTRP2 2.4435 5.7956 2.1796 24.9009
A-204 GDSC2; CTRP2 2.5939 9.2334 1.1019 28.1308
SW982 GDSC2; CTRP2 2.7833 4.8777 2.723 21.93
BT-12 CTRP2 2.9048 4.4839 2.8869 20.9764
G-402 GDSC2; CTRP2 2.9723 7.0229 2.3814 22.5731
EW-8 GDSC1; GDSC2 3.0251 4.2237 2.6048 5.4844
MES-SA GDSC2; CTRP2 3.383 5.0261 3.3416 17.8703
VA-ES-BJ GDSC1; GDSC2 3.4015 12.3667 -1.1343 24.6327
RKN GDSC2; CTRP2 3.6503 5.5702 3.5442 16.3139
SW684 GDSC1; GDSC2 3.6887 6.8567 1.8501 8.2942
BT-16 CTRP2 4.6703 8.5458 3.5219 13.5866
SK-UT-1 GDSC1; GDSC2; CTRP2 5.8206 13.4199 2.1685 16.4104
Hs 729.T CTRP2 6.0963 15.9706 1.1245 19.5493
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 2.2803 5.4702 2.0779 25.7705
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.9062 5.8463 3.7618 14.7455
RMG-I CTRP2 -2.5487 5.2868 -3.138 55.6561
A2780 GDSC2; CTRP2 0.939 3.7356 0.8937 34.1614
ES-2 GDSC1; GDSC2 1.0615 6.4239 -0.3623 29.8343
SNU-8 CTRP2 1.0826 3.5676 1.0548 33.1481
OVCAR-5 GDSC2; CTRP2 2.0501 6.6533 1.505 28.4717
IGROV-1 GDSC2; CTRP2 2.0739 5.1937 1.9103 27.0087
COV644 CTRP2 2.2253 7.0617 1.5602 27.7352
MCAS CTRP2 2.3808 4.7376 2.3125 24.6385
HEY A8 CTRP2 2.4956 4.5433 2.4551 23.7788
OC 314 CTRP2 2.4981 4.8975 2.4163 23.9032
EFO-27 GDSC2; CTRP2 2.5348 6.211 2.1675 24.6603
COV434 CTRP2 2.6062 4.286 2.5894 22.9619
OAW28 GDSC2; CTRP2 2.6069 5.1245 2.4982 23.2716
JHOM-1 CTRP2 2.633 4.7438 2.5794 22.9082
TYK-nu GDSC2; CTRP2 2.7823 5.7736 2.5545 22.5212
OVCAR-4 GDSC1; GDSC2; CTRP2 2.8059 5.8194 2.5689 22.3973
JHOC-5 CTRP2 2.9572 4.7452 2.9214 25.8554
JHOS-4 GDSC2 3.1205 9.5577 0.0347 20.3748
OV-90 GDSC2; CTRP2 3.3454 6.1299 3.0751 18.929
TOV-112D GDSC2; CTRP2 3.3918 5.6799 3.2403 18.1948
ONCO-DG-1 CTRP2 3.4334 5.2641 3.3638 17.6315
OVCAR-8 GDSC2; CTRP2 3.4596 6.9122 2.9467 19.0639
OVK18 GDSC2; CTRP2 3.4799 4.8424 3.4604 17.1506
OVTOKO GDSC2; CTRP2 3.5472 9.6431 1.8964 22.7398
SNU-119 CTRP2 3.6889 11.9377 0.9614 30.6848
ES2 CTRP2 3.7204 6.2829 3.4392 20.5892
OVCAR-3 GDSC2 3.7648 5.6274 2.5142 3.9616
OVISE GDSC2; CTRP2 3.7981 4.8123 3.791 17.7327
OV7 CTRP2 3.993 9.6473 2.3396 19.9331
OAW42 GDSC2; CTRP2 4.0644 8.426 2.9676 17.3244
EFO-21 GDSC2; CTRP2 4.0858 7.698 3.3053 15.9503
Caov-3 GDSC2; CTRP2 4.2628 7.91 3.3979 15.1176
OVSAHO CTRP2 4.5577 7.7215 3.7833 12.8262
SK-OV-3 GDSC2; CTRP2 4.7753 7.731 4.0007 11.401
SNU-840 CTRP2 5.0134 10.1456 3.0819 14.5573
TOV-21G GDSC2; CTRP2 5.0249 8.9279 3.6846 12.0748
Kuramochi GDSC1; GDSC2; CTRP2 5.2907 9.1623 3.8201 10.9102
DOV13 GDSC2; CTRP2 5.5523 12.084 2.6053 17.8757
JHOS-2 GDSC2; CTRP2 6.047 11.234 3.4518 10.8654
FU-OV-1 CTRP2 6.4339 9.5179 4.6206 5.2739
OV56 GDSC2; CTRP2 6.7897 11.6231 3.8492 7.8737
COV362 CTRP2 6.8705 10.4312 4.4955 5.078
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP2 1.0933 5.6586 0.7413 34.0982
NCI-H2452 CTRP2 1.6559 6.7798 1.0358 31.2766
IST-Mes1 GDSC1; GDSC2; CTRP2 1.9176 4.6046 1.8367 27.7662
MPP 89 GDSC1; GDSC2; CTRP2 2.0443 6.2829 1.6116 28.1288
NCI-H28 GDSC2; CTRP2 2.8549 6.2213 2.5137 22.4441
JL-1 CTRP2 4.4551 5.5916 4.4093 10.7442
NCI-H2052 GDSC2; CTRP2 4.7094 7.0147 4.2426 11.4074
ACC-MESO-1 CTRP2 4.7925 6.3243 4.5926 9.0536
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; GDSC2; CTRP2 0.6088 3.6674 0.5538 36.3884
NCI-H660 GDSC2 0.6106 2.2411 0.5731 27.3983
LNCaP clone FGC GDSC1; GDSC2; CTRP2 0.8898 4.1205 0.8041 34.6184
22Rv1 GDSC2; CTRP2 1.6672 3.1948 1.6647 34.5098
DU145 GDSC2; CTRP2 2.7269 7.6769 1.8764 25.1175
PC-3 GDSC2 4.2182 10.8819 0.2604 16.0939
PaCa-3 CTRP2 5.889 15.9834 0.9448 20.5535
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 2.9043 5.2914 2.637 20.7229
A-253 GDSC1; GDSC2; CTRP2 3.0964 6.9519 2.5405 21.6256
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MZ-MEL-7 GDSC1; GDSC2 -1.3742 1.4564 -1.4398 47.2446
G-361 GDSC2; CTRP2 -0.3222 2.2218 -0.3317 42.4424
HT-144 GDSC1; GDSC2; CTRP2 -0.2632 3.0336 -0.3074 42.1404
Malme-3M CTRP2 -0.09 6.4312 -0.7597 42.2551
G-mel GDSC2 0.0573 1.7494 0.0354 32.8706
IST-MEL1 GDSC1 0.3511 4.3635 -0.5959 30.4874
Mel Ho GDSC2; CTRP2 0.3866 2.469 0.3818 44.6079
WM278 GDSC2 0.5081 5.5265 -0.5416 33.1242
COLO 741 CTRP2 0.5633 10.1114 -1.3873 40.6737
IGR-1 GDSC2; CTRP2 0.6568 3.2254 0.6337 35.9681
COLO 783 GDSC2 0.6614 3.7757 0.2829 28.6423
LOX-IMVI GDSC1; GDSC2; CTRP2 0.8116 2.7864 0.8063 34.8793
SH-4 GDSC1; GDSC2 0.9313 4.1319 0.4543 26.4984
LB2518-MEL GDSC1; GDSC2 0.9711 3.5862 0.6797 25.1221
SK-MEL-30 GDSC2; CTRP2 0.9742 3.4393 0.95 33.8582
UACC-62 GDSC2; CTRP2 1.0282 2.7692 1.0253 33.4283
A-388 GDSC1; GDSC2 1.0514 4.5101 0.442 26.0184
Hs 944.T CTRP2 1.1055 3.689 1.0708 33.0186
451Lu GDSC2 1.1264 3.1614 0.9677 22.8605
Hs 938.T GDSC2 1.1325 5.2916 0.2088 26.8559
COLO 800 GDSC1; GDSC2; CTRP2 1.2172 3.4064 1.2017 32.2111
WM88 CTRP2 1.2244 3.6347 1.1976 32.2005
UACC-257 GDSC1; GDSC2; CTRP2 1.2298 5.0688 1.0207 32.7592
WM266-4 CTRP2 1.2742 2.5753 1.2738 31.7809
SK-MEL-5 GDSC2; CTRP2 1.3219 3.212 1.3148 31.4855
LB373-MEL-D GDSC1; GDSC2 1.4195 4.144 0.975 21.5016
SK-MEL-3 GDSC2; CTRP2 1.5056 4.9413 1.3427 30.782
MeWo CTRP2 1.5588 5.0782 1.375 30.4983
A-431 GDSC2 1.576 6.4569 0.137 25.3459
K029AX CTRP2 1.6924 3.2027 1.6899 29.0018
Hs 294T CTRP2 1.7009 2.4749 1.7009 28.9367
M14 GDSC2 1.7096 4.7189 1.052 19.841
A101D GDSC1; GDSC2; CTRP2 1.7117 3.3541 1.7072 28.8801
CP66-MEL GDSC1; GDSC2 1.7537 4.1709 1.3218 18.1107
RVH-421 GDSC2; CTRP2 1.7773 3.292 1.7745 28.4375
SK-MEL-31 GDSC2; CTRP2 1.8206 3.9997 1.793 28.2319
SK-MEL-2 GDSC1; GDSC2; CTRP2 1.8371 3.7066 1.8251 28.0696
WM115 GDSC2; CTRP2 1.8372 2.3783 1.8372 28.0292
Hs 852.T CTRP2 1.8702 6.03 1.4929 29.0872
MZ-MEL-2 GDSC1; GDSC2 1.9423 4.4226 1.4194 16.7635
SK-MEL-24 GDSC2; CTRP2 1.997 3.7104 1.9884 26.9929
DJM-1 GDSC1; GDSC2 2.0404 6.1387 0.7419 20.3103
IPC-298 GDSC2; CTRP2 2.0505 6.1881 1.6456 27.9929
A2058 GDSC2; CTRP2 2.2493 3.9733 2.2369 25.3249
VMRC-MELG GDSC2 2.2509 5.1423 1.4158 15.5763
COLO 829 GDSC1; GDSC2; CTRP2 2.2687 5.1676 2.1259 25.6409
CP50-MEL-B GDSC2 2.3088 5.2981 1.4003 15.4534
RPMI-7951 GDSC2; CTRP2 2.3772 4.3142 2.3501 24.5224
WM983B CTRP2 2.4123 6.2534 2.0215 25.5545
A-375 GDSC2; CTRP2 2.4439 4.6683 2.3877 24.1765
SK-MEL-1 GDSC1 2.6282 5.2067 1.1262 8.3656
GAK GDSC2 2.6296 3.8752 2.3668 8.4176
WM35 GDSC2 2.7139 6.5682 1.1679 15.4306
WM793 GDSC2; CTRP2 2.761 3.4346 2.761 21.8744
COLO 792 GDSC2; CTRP2 2.7744 8.0296 1.7894 25.2847
Hs 936.T CTRP2 2.7749 3.2037 2.7749 21.7818
WM1799 CTRP2 2.8179 6.5666 2.368 23.0812
IGR-37 GDSC2; CTRP2 2.855 6.6016 2.397 22.8647
Mel JuSo GDSC2; CTRP2 2.8601 5.9833 2.5858 22.1698
MDA-MB-435S CTRP2 2.8752 4.2982 2.8655 21.1461
SK-MEL-28 GDSC2; CTRP2 2.9943 5.0294 2.928 20.5449
HMCB CTRP2 3.1217 8.7506 1.8558 24.0523
HMV-II GDSC2 3.1617 5.716 1.9889 8.9152
MMAc-SF GDSC1; GDSC2 3.2839 10.8049 -0.4513 22.1612
CJM [Human melanoma] CTRP2 3.3731 5.0814 3.3246 17.9604
COLO 679 GDSC2 3.4408 5.8285 2.1663 6.9777
WM1552C GDSC2 3.4986 6.3808 1.9371 8.2616
CHL-1 GDSC2 3.5277 6.06 2.1204 7.0284
IGR-39 CTRP2 5.6841 8.5526 4.4787 7.311
Hs 895.T CTRP2 6.0576 13.6586 2.2483 15.6334
Hs 940.T GDSC2; CTRP2 6.2652 8.7328 4.8795 4.4864
WT2-iPS GDSC2; CTRP2 6.6521 13.1631 2.9779 11.6621
Hs 688(A).T CTRP2 7.45 8.4613 5.7146 0.1414
Hs 934.T CTRP2 7.5323 8.743 5.6443 0.2387
Hs 839.T CTRP2 8.304 17.9523 1.8524 13.1411
EquiPSC Line K2 GDSC2 1.3616 5.8415 0.2036 25.8968
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 0.9241 2.7119 0.8429 24.4793
Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GSS CTRP2 -3.255 4.029 -3.6337 59.6222
TMK-1 GDSC2 -1.5035 3.8687 -2.1031 48.7875
ECC10 GDSC2; CTRP2 -1.0313 2.4422 -1.0668 47.1888
ECC12 GDSC1; GDSC2; CTRP2 -0.311 2.4336 -0.3264 42.3839
SNU-620 CTRP2 0.0147 1.6045 0.0144 40.1718
AGS GDSC2; CTRP2 0.0395 1.7659 0.0387 47.331
NUGC-4 GDSC2; CTRP2 0.1245 3.6611 0.0451 46.7882
SCH GDSC1; GDSC2 0.461 3.7031 0.0878 30.5807
SNU-16 GDSC1; CTRP2 0.6306 2.9745 0.6173 36.1111
Fu97 CTRP2 1.0028 4.6986 0.8427 36.6041
NUGC-3 GDSC2; CTRP2 1.1902 2.9503 1.1864 32.3519
HSC-39 GDSC1 1.3251 3.2746 0.8807 15.5778
SK-GT-2 GDSC2 1.4616 3.4336 1.2601 19.735
RF-48 GDSC1; GDSC2 1.5729 4.9646 0.8055 21.8006
MKN7 GDSC2; CTRP2 1.6269 5.6525 1.3246 30.4408
IM95 GDSC2; CTRP2 1.656 3.5878 1.6441 29.2757
GSU CTRP2 1.6654 4.5222 1.5788 29.4642
Hs 746.T GDSC2; CTRP2 1.8328 4.4557 1.7646 28.2877
KATO III GDSC2; CTRP2 2.0331 5.2211 1.8609 27.3097
OCUM-1 GDSC2; CTRP2 2.2896 5.5414 2.0722 25.7607
SNU-5 GDSC1; GDSC2; CTRP2 2.3884 4.9579 2.169 23.7036
NCI-N87 GDSC2; CTRP2 2.4436 5.2073 2.1599 23.5269
23132/87 GDSC2; CTRP2 2.5136 4.6601 2.4624 23.6953
KE-39 CTRP2 2.6396 6.5893 2.1667 24.343
SNU-601 CTRP2 2.7321 5.0431 2.6455 22.3611
HGC-27 GDSC2; CTRP2 2.9378 7.9963 1.9757 24.1471
LMSU CTRP2 2.9942 6.96 2.4273 22.341
MKN74 CTRP2 3.0713 6.5191 2.6587 21.2666
SNU-1 GDSC1; GDSC2; CTRP2 3.1342 7.0497 2.5466 21.4929
SNU-216 CTRP2 3.2965 8.2021 2.2694 22.0573
RERF-GC-1B GDSC2 3.3066 7.8526 1.0438 14.3001
SH-10-TC CTRP2 3.3523 5.8084 3.1674 18.5763
MKN1 GDSC2; CTRP2 3.4071 6.7132 2.9593 19.1696
SNU-668 CTRP2 3.4629 7.9118 2.1465 21.1231
HuG1-N CTRP2 3.8312 7.6068 3.0763 17.5269
GCIY GDSC1; GDSC2 3.8651 8.6513 1.0953 12.421
MKN28 GDSC2 3.9628 6.1272 2.4108 4.1501
SNU-719 CTRP2 5.2139 10.6254 3.0297 17.7437
MKN45 GDSC2; CTRP2 8.1602 14.4519 3.4463 7.4005
SNG-M GDSC2; CTRP2 1.2406 4.4174 1.1399 32.3368
SNU-685 CTRP2 1.5209 5.7341 1.189 31.2358
SNU-1077 CTRP2 4.0012 6.3465 3.7253 14.5902
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC1; GDSC2 -0.1 4.9054 -0.939 37.6767
KMH-2 GDSC2 1.1669 3.4043 0.9471 22.7836
8505C GDSC2; CTRP2 1.4221 5.0365 1.2351 37.0937
SW579 CTRP2 1.8635 6.3018 1.4088 29.3902
CGTH-W-1 GDSC1; CTRP2 2.0014 5.5413 1.7587 27.762
IHH-4 GDSC2 2.2596 3.2665 2.1772 11.0929
8305C GDSC2; CTRP2 2.3531 4.314 2.3251 24.6859
HTC-C3 GDSC2 2.3587 4.9247 1.6235 13.9209
FTC-238 CTRP2 2.5212 4.3042 2.5004 23.5416
FTC-133 GDSC2; CTRP2 2.5619 3.5053 2.5617 23.2015
ASH-3 GDSC2 2.6463 4.7269 1.9995 10.5685
B-CPAP GDSC2; CTRP2 2.7676 5.4731 2.6065 22.3842
BHT-101 GDSC2; CTRP2 2.7809 6.9386 1.8859 23.5333
TT CTRP2 3.6593 6.335 3.3567 21.1931
WRO GDSC2 3.9157 5.9505 2.4636 3.9316
ML-1 [Human leukemia] GDSC2; CTRP2 4.0499 6.8219 3.615 14.8605
TT2609-C02 GDSC2; CTRP2 4.306 8.9568 2.9701 16.6957
CAL-62 GDSC2; CTRP2 5.3839 8.9143 4.0276 9.843
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-15A GDSC2 -0.1263 4.4978 -0.8171 37.4188
BB30-HNC GDSC1; GDSC2 1.0659 4.8053 0.3408 26.4793
BICR 18 CTRP2 1.2173 4.9113 1.0369 32.7496
PCI-06A GDSC2 1.4566 3.2499 1.3055 19.5116
KOSC-2 GDSC2 1.4713 3.6645 1.1994 20.0253
JHU-029 GDSC2 1.4879 4.4305 0.9373 21.4184
JHU-011 GDSC2 1.4988 5.5984 0.4516 24.0405
PE/CA-PJ49 CTRP2 1.5653 3.1458 1.5625 29.8497
SNU-899 CTRP2 1.7808 5.1927 1.4411 31.1726
SAS GDSC2 1.7891 5.0226 1.0032 19.798
HO-1-N-1 GDSC2 1.9023 3.9594 1.5615 16.1099
OSC-19 GDSC2 2.1212 6.2095 0.7865 19.7548
NCI-H3118 GDSC2 2.2916 4.4965 1.7495 13.4208
SKN-3 GDSC2 2.3724 5.7321 1.2564 16.0858
BICR 56 CTRP2 2.3856 5.1436 2.2564 24.8162
SCC-9 GDSC2; CTRP2 2.4208 6.3768 1.9943 25.624
KON GDSC2 2.425 5.6944 1.3249 15.4847
SAT [Human HNSCC] GDSC2 2.6224 4.5425 2.0623 10.2725
CAL-27 GDSC2; CTRP2 2.6391 4.3895 2.6172 22.7598
SCC-25 GDSC2; CTRP2 2.6503 6.8669 2.087 24.5953
BICR 78 GDSC2 2.6718 4.502 2.1301 9.6765
Detroit 562 GDSC2; CTRP2 2.7521 6.0759 2.4428 23.0121
BB49-HNC GDSC1; GDSC2 2.7658 11.8384 -1.4082 27.5652
Ca9-22 GDSC2 2.8271 4.4124 2.3244 7.9188
SNU-1066 CTRP2 2.8555 7.001 2.2629 23.3493
BICR 22 GDSC2; CTRP2 2.9114 5.7475 2.7015 21.5994
SCC-4 GDSC2; CTRP2 2.9128 5.3995 2.7788 21.3222
PCI-04B GDSC2 2.9868 7.3528 1.0208 15.4181
SNU-1214 CTRP2 2.9882 4.9858 2.8161 19.4932
SNU-46 CTRP2 3.0893 5.9287 2.6176 20.0828
DOK GDSC2 3.3534 5.6458 2.1861 7.0997
SNU-1076 CTRP2 3.4907 5.701 3.3431 17.5228
BICR 6 CTRP2 3.5658 6.0236 3.345 17.2844
YD-8 CTRP2 3.7078 6.1987 3.4506 16.472
HSC-3 GDSC2; CTRP2 3.824 6.3215 3.5402 15.7965
FaDu GDSC2; CTRP2 3.8271 6.9235 3.3382 16.5402
BHY GDSC2; CTRP2 3.8649 9.1314 2.4486 19.8496
JHU-022 GDSC2 3.9146 9.6459 0.6392 14.8855
BICR 10 GDSC2 3.9905 10.3744 0.3362 16.3069
OSC-20 GDSC2 4.0142 6.6912 2.1736 5.486
SCC-15 GDSC2 4.0636 8.0744 1.5319 9.299
HSC-2 GDSC2; CTRP2 4.0677 8.1158 3.1075 16.7692
PE/CA-PJ34 (clone C12) CTRP2 4.1161 6.4859 3.8047 13.9586
BICR 31 GDSC2; CTRP2 4.1307 7.3405 3.5003 15.0729
YD-10B CTRP2 4.1577 6.236 3.6105 10.8925
HSC-4 GDSC2; CTRP2 4.172 7.3704 3.5317 14.8386
PE/CA-PJ41 (clone D2) CTRP2 4.1982 6.6895 3.8227 13.6533
UPCI-SCC-090 GDSC2 4.4524 7.4382 2.1125 4.9233
LB771-HNC GDSC1; GDSC2 4.6267 8.4601 1.742 6.7577
SNU-1041 CTRP2 4.7962 8.4658 3.6832 12.6269
CAL-33 GDSC2; CTRP2 4.9307 7.6455 4.1963 10.2243
PE/CA-PJ15 GDSC2; CTRP2 4.9618 9.2587 3.465 13.1195
BICR 16 CTRP2 5.5943 10.2374 3.5619 11.3229
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 GDSC2; CTRP2 0.4308 2.4681 0.4265 44.2587
TCCSUP GDSC2; CTRP2 0.5312 3.2082 0.5051 43.5305
UM-UC-1 CTRP2 0.7609 5.5983 0.3937 36.2976
KU-19-19 GDSC2; CTRP2 1.1466 3.6011 1.119 32.7215
U-BLC1 CTRP2 1.6987 3.1069 1.6972 28.9565
HT-1197 GDSC2; CTRP2 1.9426 2.4143 1.9426 27.3268
KMBC-2 CTRP2 2.181 6.3882 1.7295 27.2933
647V GDSC2; CTRP2 2.3236 4.5341 2.2749 24.9525
JMSU-1 CTRP2 2.5448 4.4081 2.5179 23.4052
RT-112 GDSC2; CTRP2 2.5768 7.5832 1.7513 26.0036
SCaBER CTRP2 2.6924 4.7416 2.6425 22.4997
SW780 GDSC2 2.7508 6.2746 1.3463 14.2287
253J CTRP2 2.7997 6.2533 2.4442 22.8617
HT-1376 CTRP2 3.0138 5.1322 2.9341 20.4612
253J-BV CTRP2 3.0686 6.9136 2.5238 21.7687
CAL-29 GDSC2; CTRP2 3.2144 6.4049 2.8505 20.1397
VM-CUB-1 CTRP2 3.3158 6.148 3.0376 19.1544
SW1710 GDSC2; CTRP2 3.4056 6.1675 3.1301 18.5474
BC-3C CTRP2 3.5473 7.2272 2.9247 18.8953
RT-4 GDSC2; CTRP2 3.7996 7.3364 3.1513 17.3268
T24 GDSC2; CTRP2 4.3699 8.416 3.2818 15.2994
BFTC-905 GDSC2; CTRP2 4.617 6.9058 4.1891 11.0802
639V GDSC2; CTRP2 5.217 6.9826 4.7839 7.1472
J82 GDSC2; CTRP2 5.363 12.1179 2.4226 16.3993
UM-UC-3 CTRP2 6.1885 9.221 4.5746 5.9054
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NT2-D1 GDSC1 -2.2384 1.5615 -2.4698 55.7263
NEC8 GDSC1; GDSC2 -2.1208 0.6952 -2.157 54.429
NCC-IT GDSC1 -1.3026 0.1387 -1.3078 45.3287
DSH1 GDSC1; GDSC2 -0.5226 6.2439 -1.9194 42.4078
JAR GDSC1; GDSC2 -0.3913 1.896 -0.4484 37.5273
PA-1 GDSC2 0.2377 2.5728 0.127 31.5041
SW954 GDSC1; GDSC2 0.5055 5.599 -0.5745 33.2664
JEG-3 GDSC2 0.9021 3.2054 0.712 25.2727
HT-3 GDSC2 0.9594 5.6504 -0.1245 29.2293
KGN GDSC1 0.9932 11.0104 -3.1739 36.5433
LB831-BLC GDSC1; GDSC2 1.176 3.9955 0.7668 23.7218
SKG-IIIa GDSC2 1.525 4.8965 0.7847 22.1159
CAL-39 GDSC2 1.9776 4.7762 1.3047 17.2926
HEY GDSC2 1.9973 5.1886 1.1408 18.1766
DoTc2 4510 GDSC2 2.2213 5.4577 1.2396 16.7405
BPH-1 GDSC2 2.2723 8.3466 -0.1111 23.9115
TC-YIK GDSC2 2.2916 4.9797 1.5313 14.7294
SW962 GDSC1; GDSC2 2.4136 8.0191 0.1792 21.9814
OVCA420 GDSC2 2.4401 4.456 1.9189 11.83
OV17R GDSC2 2.564 6.867 0.8839 17.6132
OVCA433 GDSC2 2.877 6.7455 1.2265 14.5408
HeLa GDSC2; CTRP2 2.8956 5.0953 2.8129 21.2586
ACC-OV7 GDSC2 2.9603 6.7379 1.3039 13.804
PWR-1E GDSC2 3.0427 4.2136 2.6263 5.2895
SiSo GDSC2 3.1333 7.952 0.8479 15.9682
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 3.2396 5.6787 2.0743 8.1406
C-33 A GDSC2 3.2589 4.8528 2.5033 5.3694
PEO1 GDSC2 3.3426 5.675 2.1625 7.2799
ME-180 GDSC2 3.3566 5.2476 2.3878 5.8141
HEC-1 GDSC2 3.3773 5.9182 2.0696 7.7672
C-4-I GDSC2 3.3899 10.8756 -0.3984 21.6056
UWB1.289 GDSC2 3.5102 8.142 1.0669 13.5688
Ca Ski GDSC2 3.8102 6.6252 2.0575 6.6896
OVMIU GDSC2 3.9053 6.791 2.0463 6.5259
SKN GDSC2 3.9745 7.9489 1.5272 9.55
SW756 GDSC2 4.0913 9.4593 0.8685 13.1346
SiHa GDSC2 4.2536 7.424 1.9858 6.0963
JHOS-3 GDSC2 4.5906 6.42 2.6587 1.6472
MS751 GDSC2 4.6904 9.0854 1.4855 8.1297
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 ClinicalTrials.gov (NCT03538171) Ph3 Study of Exemestane With or Without Entinostat in Chinese Patients With Hormone Receptor-Positive, Locally Advanced or Metastatic Breast Cancer. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.
4 Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests. Arch Toxicol. 2017 Feb;91(2):839-864.
5 A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.