Details of the Drug

General Information of Drug (ID: DMHJQYS)

Drug Name

TEI-5178

Synonyms

[1R-[1alpha,2beta(1E,3S*),3alpha]]-6-[[2-(3-Cyclohexyl-3-hydroxy-1-propenyl)-3-hydroxy-5-oxocyclopentyl]thio]hexanoic acid methyl ester; 15-Cyclohexyl-16,17,18,19,20-pentanor-7-thiaprostaglandin E1 methyl ester

Indication

Disease Entry	ICD 11	Status	REF
Nephritis	GB40	Phase 1	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C21H34O5S
Canonical SMILES: COC(=O)CCCCCSC1C(C(CC1=O)O)C=CC(C2CCCCC2)O
InChI: 1S/C21H34O5S/c1-26-20(25)10-6-3-7-13-27-21-16(18(23)14-19(21)24)11-12-17(22)15-8-4-2-5-9-15/h11-12,15-18,21-23H,2-10,13-14H2,1H3/b12-11+/t16-,17?,18+,21+/m0/s1
InChIKey: QNKCYDKEIICCMC-RJOSLXAASA-N

Cross-matching ID

PubChem CID: 6439633
CAS Number: 83009-96-5
TTD ID: D04DSD

References

1	Antinephritic effects of PGE1 and thiaprostaglandin E1, TEI-5178 and TEI-6122, on crescentic-type anti-GBM nephritis in rats. Jpn J Pharmacol. 1989 Dec;51(4):521-30.