Details of the Drug

General Information of Drug (ID: DMHQEA0)

Drug Name

Oltipraz

Synonyms

CB-1400; Oltipraz (mucositis/radiation sickness/cancer); Oltipraz (mucositis/radiation sickness/cancer), Canopus Biopharma; Syntheticdithiolethione (oral, acute radiation syndrome/mucositis/cancer), Canopus

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 3	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C8H6N2S3
Canonical SMILES: CC1=C(SSC1=S)C2=NC=CN=C2
InChI: 1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H,1H3
InChIKey: CKNAQFVBEHDJQV-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 47318
ChEBI ID: CHEBI:77319
CAS Number: 64224-21-1
UNII: 6N510JUL1Y
DrugBank ID: DB12539
TTD ID: D0W4NM

Combinatorial Drugs (CBD)

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References

1	ClinicalTrials.gov (NCT02068339) Efficacy and Safety of Oltipraz for Liver Fat Reduction in Patients With Non-Alcoholic Fatty Liver Disease Except for Liver Cirrhosis. U.S. National Institutes of Health.