Details of the Drug

General Information of Drug (ID: DMI6KQM)

Drug Name
GSK1059615
Synonyms KS-00001CUQ; CTK8F0346; HMS3654N17; BCP02498; AKOS026750445; NCGC00346509-01; FT-0669060
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Discontinued in Phase 1 [1]
Endometrial cancer 2C76 Discontinued in Phase 1 [1]
Lymphoma 2A80-2A86 Discontinued in Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 333.4
Logarithm of the Partition Coefficient (xlogp) 3
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C18H11N3O2S
IUPAC Name
(5Z)-5-[(4-pyridin-4-ylquinolin-6-yl)methylidene]-1,3-thiazolidine-2,4-dione
Canonical SMILES
C1=CC2=NC=CC(=C2C=C1/C=C\\3/C(=O)NC(=O)S3)C4=CC=NC=C4
InChI
InChI=1S/C18H11N3O2S/c22-17-16(24-18(23)21-17)10-11-1-2-15-14(9-11)13(5-8-20-15)12-3-6-19-7-4-12/h1-10H,(H,21,22,23)/b16-10-
InChIKey
QDITZBLZQQZVEE-YBEGLDIGSA-N
Cross-matching ID
PubChem CID
23582824
ChEBI ID
CHEBI:71955
CAS Number
958852-01-2
UNII
07YMO87363
DrugBank ID
DB11962
TTD ID
D0L0ZC
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Breast cancer
ICD Disease Classification 2C60-2C65
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase gamma (PIK3CG) DTT PIK3CG 1.98E-01 -0.05 -0.55
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 0.6738 4.8226 0.1934 46.5495
HuO9 GDSC1 -3.4029 0.3508 -3.4396 83.6396
H-EMC-SS GDSC1 -3.3551 0.1279 -3.3799 84.2997
ES4 GDSC1 -3.0871 -0.8685 -3.0884 87.0329
ES5 GDSC1 -2.8686 0.4819 -2.8956 81.235
EW-1 GDSC1 -2.7864 -0.0655 -2.7943 82.7649
NOS-1 [Human HNSCC] GDSC1 -2.7775 -0.0863 -2.7849 82.7935
EW-7 GDSC1 -2.5465 -0.5342 -2.5475 82.9403
ES7 GDSC1 -2.4039 1.2476 -2.461 76.5069
EW-13 GDSC1 -1.8652 0.8265 -1.8808 74.2956
ES8 GDSC1 -1.8477 0.7403 -1.8601 74.3743
MHH-ES-1 GDSC1 -1.815 0.3882 -1.8194 74.9227
EW-16 GDSC1 -1.7186 0.8023 -1.7304 73.1913
EW-3 GDSC1 -1.481 1.4554 -1.5153 69.8017
EW-18 GDSC1 -1.3123 0.7401 -1.3168 69.5633
CADO-ES1 GDSC1 -1.2649 1.0741 -1.2761 68.5932
CHSA8926 GDSC1 -1.2363 2.7054 -1.3913 65.3497
TC-71 GDSC1 -1.2234 0.5638 -1.2252 68.8423
ES1 GDSC1 -1.2211 2.1726 -1.3042 66.2337
HOS GDSC1; CTRP2 -1.2126 4.6645 -1.6842 42.6621
EW-22 GDSC1 -0.9904 1.4401 -1.0084 65.35
SK-PN-DW GDSC1 -0.9679 1.0646 -0.974 65.5592
ES6 GDSC1 -0.7945 3.2161 -1.0033 61.0239
SK-ES-1 GDSC1; CTRP2 -0.6908 1.922 -0.7098 38.2688
CAL-72 GDSC1 -0.6451 2.7107 -0.7589 60.3571
G-292 clone A141B1 GDSC1; CTRP2 -0.4324 4.6939 -0.8406 37.6473
SK-N-MC CTRP2 -0.4191 1.6103 -0.4241 36.4151
NY GDSC1 -0.2677 2.9716 -0.3932 56.4329
U2OS GDSC1 -0.1616 2.4307 -0.2132 55.6397
HuO-3N1 GDSC1 -0.0153 5.1459 -0.6596 52.9141
TC71 CTRP2 0.115 2.5645 0.0886 32.9279
A-673 GDSC1; CTRP2 0.1859 2.7677 0.1489 32.4907
SJSA-1 GDSC1 0.2724 3.8487 0.0222 50.5216
SaOS-2 GDSC1; CTRP2 0.4445 4.0899 0.2491 31.2941
CAL-78 GDSC1; CTRP2 0.4805 6.0881 -0.256 32.7536
MG-63 GDSC1; CTRP2 0.5985 4.3445 0.3641 30.4037
Hs 888.T CTRP2 0.8873 5.7818 0.2867 29.717
EW-24 GDSC1 2.8678 4.9411 2.5314 20.4538
Hs 822.T CTRP2 5.4206 11.9525 1.8987 12.4025
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 194 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -0.1601 3.5224 -0.304 35.1307
JM1 GDSC1; CTRP2 -0.1437 2.6851 -0.1887 34.711
Ri-1 CTRP2 -6.4479 4.4084 -7.3297 66.4903
DoHH2 GDSC1 -3.3227 -1.1945 -3.3234 89.1886
SU-DHL-6 GDSC1; CTRP2 -3.0606 1.3546 -3.1306 53.8078
NALM-6 GDSC1 -2.7195 -0.4333 -2.7219 83.6747
SU-DHL-16 GDSC1 -2.7078 -1.5938 -2.7078 86.9992
PL-21 GDSC1 -2.6549 2.1936 -2.8344 74.8957
HAL-01 GDSC1 -2.4722 0.3249 -2.4844 79.7882
Ku812 GDSC1 -2.3 -0.1484 -2.3022 80.1078
SU-DHL-5 GDSC1 -2.1862 -0.4939 -2.1865 80.0572
NK-92MI GDSC1 -2.1371 0.9379 -2.1646 75.8885
CESS GDSC1 -2.1143 -0.097 -2.1159 78.5431
RS4;11 GDSC1 -2.0358 2.0289 -2.1511 72.2324
697 GDSC1; CTRP2 -2.0294 -0.0736 -2.0301 47.1282
Ramos.2G6.4C10 GDSC1 -2.0066 0.1339 -2.0095 77.1113
NU-DUL-1 GDSC1; CTRP2 -1.8517 -0.1208 -1.8519 45.9433
A4/Fukuda GDSC1; CTRP2 -1.813 2.0371 -1.8816 45.8051
MN-60 GDSC1 -1.8084 0.4627 -1.8139 74.7034
THP-1 GDSC1; CTRP2 -1.8017 1.1353 -1.8176 45.643
ALL-SIL GDSC1 -1.735 1.0808 -1.7575 72.6736
ALL-PO GDSC1 -1.6857 1.1882 -1.7119 72.0352
Karpas-620 GDSC1; CTRP2 -1.6651 4.6543 -2.1752 45.4337
MOLP-8 GDSC1; CTRP2 -1.6549 0.8274 -1.6609 44.6471
Karpas-231 GDSC1 -1.6468 0.7055 -1.6549 72.7901
GDM-1 GDSC1; CTRP2 -1.6186 4.0724 -1.9867 44.9853
KMS-12-BM GDSC1 -1.5935 1.6176 -1.6437 70.3268
BC-1 GDSC1 -1.579 0.111 -1.5797 73.1582
MV4-11 GDSC1 -1.5546 0.577 -1.5591 72.1971
MC116 GDSC1; CTRP2 -1.5364 -0.1539 -1.5364 43.8421
GR-ST GDSC1 -1.4907 1.7594 -1.5477 69.2211
Loucy GDSC1 -1.4845 0.4875 -1.4873 71.6638
HH [Human lymphoma] GDSC1; CTRP2 -1.3656 3.6839 -1.6321 43.2593
OCI-AML-5 GDSC1; CTRP2 -1.3388 0.7764 -1.3413 42.5334
Pfeiffer CTRP2 -1.3107 1.9853 -1.3535 42.4508
MOLM-13 GDSC1 -1.3053 0.9574 -1.314 69.1695
CCRF-CEM GDSC1 -1.1999 0.9623 -1.2071 68.1143
KOPN-8 GDSC1 -1.1852 2.0322 -1.2518 66.1961
CTB-1 GDSC1 -1.1821 4.244 -1.6636 62.3749
MY-M12 GDSC1 -1.1399 3.3586 -1.406 63.484
ST486 GDSC1; CTRP2 -1.1154 0.7431 -1.1165 41.041
OPM-2 GDSC1; CTRP2 -1.0939 1.3144 -1.102 40.9189
QIMR-WIL GDSC1 -1.0807 1.4656 -1.1024 66.2053
SR GDSC1; CTRP2 -1.0747 1.6117 -1.091 40.815
MHH-PREB-1 GDSC1 -1.0029 1.774 -1.0398 64.9966
LP-1 GDSC1; CTRP2 -1.0018 2.7539 -1.0985 40.5473
RPMI-8866 GDSC1 -0.9686 1.5937 -0.9934 64.9253
GA-10 GDSC1; CTRP2 -0.948 0.9888 -0.95 39.9287
EM-2 GDSC1 -0.9382 2.0643 -0.9952 63.954
OCI-M1 GDSC1; CTRP2 -0.9286 1.1626 -0.9322 39.8043
DEL GDSC1 -0.9233 2.9773 -1.0993 62.4281
JJN-3 GDSC1; CTRP2 -0.9008 5.4208 -1.5503 41.0894
TUR GDSC1 -0.9007 1.0431 -0.9055 64.8445
SU-DHL-10 GDSC1; CTRP2 -0.8718 -0.198 -0.8718 39.4143
P30/OHK GDSC1 -0.8656 1.4864 -0.8822 64.0148
KE-37 GDSC1 -0.8523 1.173 -0.859 64.1948
BL-70 CTRP2 -0.8456 1.0782 -0.8477 39.2467
P32/ISH GDSC1 -0.8426 1.105 -0.8478 64.1456
VAL GDSC1 -0.8215 2.4792 -0.9163 62.281
WIL2 NS GDSC1 -0.8174 1.7515 -0.8458 63.207
YT GDSC1 -0.7978 1.6481 -0.82 63.1272
ML-2 GDSC1 -0.7692 1.913 -0.8063 62.5257
MOLT-16 GDSC1; CTRP2 -0.7414 2.0023 -0.7654 38.6211
RCH-ACV GDSC1; CTRP2 -0.7347 3.4006 -0.9017 38.9772
Daudi GDSC1; CTRP2 -0.7299 3.1722 -0.8624 38.8538
ATN-1 GDSC1 -0.662 4.3125 -1.1146 58.6414
BC-3 GDSC1 -0.6083 0.9254 -0.6095 61.529
EB1 CTRP2 -0.576 3.8716 -0.8135 38.1287
Jurkat GDSC1 -0.5751 1.6934 -0.5929 60.7011
Farage GDSC1 -0.5355 2.1717 -0.5824 59.8561
OCI-AML-3 GDSC1; CTRP2 -0.4698 2.7865 -0.5399 36.9561
PF-382 GDSC1 -0.4663 2.0197 -0.4987 59.2522
HT GDSC1 -0.4609 2.7477 -0.5673 58.5501
BL-41 GDSC1 -0.4458 0.4055 -0.4458 59.5959
NOMO-1 GDSC1; CTRP2 -0.4353 5.137 -0.9613 37.9595
Jiyoye GDSC1 -0.4127 1.8277 -0.4321 58.7968
HC-1 GDSC1 -0.3677 4.384 -0.8131 56.2523
SUP-B15 GDSC1; CTRP2 -0.3631 5.469 -0.9781 37.7242
RPMI-8402 GDSC1 -0.3627 1.7747 -0.3783 58.2596
KCL-22 GDSC1 -0.3559 2.6875 -0.4474 57.5483
Sc-1 GDSC1 -0.3526 2.592 -0.4322 57.591
BV-173 GDSC1; CTRP2 -0.2965 5.343 -0.8685 37.2025
JURL-MK1 GDSC1 -0.2801 2.4617 -0.3411 56.9189
EB2 GDSC1 -0.2485 2.1898 -0.284 56.7372
KG-1 GDSC1 -0.2426 2.5743 -0.3135 56.4431
MOLT-4 GDSC1 -0.2355 1.8603 -0.2514 56.7492
H9 GDSC1 -0.2009 2.5892 -0.271 55.985
KMOE-2 GDSC1 -0.1736 2.7311 -0.259 55.6091
MM1.S CTRP2 -0.1622 3.4479 -0.2949 35.11
CA46 GDSC1; CTRP2 -0.1442 3.5553 -0.292 35.0376
Karpas-45 GDSC1 -0.1285 2.4846 -0.1836 55.2452
EoL-1 GDSC1; CTRP2 -0.1276 1.5435 -0.1293 34.4619
L-363 GDSC1; CTRP2 -0.0393 2.872 -0.0953 34.0518
HL-60 GDSC1; CTRP2 -0.0207 2.6588 -0.0585 33.869
RPMI-8226 GDSC1; CTRP2 0.022 3.5369 -0.1109 33.8912
SUP-M2 GDSC1; CTRP2 0.0425 2.2334 0.0294 33.3669
MLMA GDSC1 0.0811 2.7881 0.0047 52.7832
TK [Human B-cell lymphoma] GDSC1 0.1002 3.7652 -0.1461 52.3083
NKM-1 GDSC1 0.1084 3.3178 -0.0464 52.3443
Hs 445 GDSC1 0.1149 3.8602 -0.152 52.1354
SU-DHL-8 GDSC1; CTRP2 0.1279 2.9315 0.0748 32.9301
VL51 GDSC1 0.1438 3.8712 -0.123 51.8408
Namalwa CTRP2 0.1918 3.1961 0.1153 32.5815
Mino CTRP2 0.1954 2.8034 0.1561 32.4354
MOLM-16 CTRP2 0.1996 4.1136 -0.0209 32.9945
EJM GDSC1; CTRP2 0.2186 3.0713 0.157 32.3544
JeKo-1 CTRP2 0.278 5.5635 -0.3078 33.5993
Kasumi-2 CTRP2 0.2793 4.1382 0.0605 32.463
KMS-20 CTRP2 0.2963 3.2377 0.2213 31.882
SUP-T1 GDSC1; CTRP2 0.3217 4.1027 0.1136 32.1486
Hs 611.T CTRP2 0.3745 3.6819 0.2449 31.5421
KMS-11 GDSC1; CTRP2 0.3807 8.396 -1.2343 35.6554
SU-DHL-4 GDSC1; CTRP2 0.4041 3.0403 0.355 31.0782
RPMI-6666 GDSC1; CTRP2 0.4525 3.7473 0.3184 31.0391
Karpas-422 GDSC1; CTRP2 0.4642 5.0315 0.0494 31.8729
Reh GDSC1; CTRP2 0.5053 5.3391 0.0073 31.8677
U-698-M GDSC1 0.5186 3.1066 0.4289 47.7013
LC4-1 GDSC1 0.5298 4.0228 0.2612 47.7905
NB4 GDSC1; CTRP2 0.5608 5.5692 -0.0015 31.7096
P12-Ichikawa GDSC1 0.5888 2.5018 0.5652 46.7318
Kasumi-1 CTRP2 0.602 3.687 0.4881 29.9781
MOLT-3 CTRP2 0.6036 2.7173 0.5848 29.6479
JSC-1 GDSC1 0.6198 2.8862 0.5644 46.4293
DB GDSC1; CTRP2 0.6244 3.909 0.4765 29.9434
LAMA-84 GDSC1 0.6248 3.6246 0.4539 46.601
BALL-1 GDSC1 0.6349 4.2277 0.3235 46.7147
BE-13 GDSC1 0.6938 3.2181 0.6 45.6337
SUP-HD1 GDSC1; CTRP2 0.7069 2.8941 0.6817 28.9811
NU-DHL-1 CTRP2 0.7151 3.1127 0.6746 28.9781
AML-193 CTRP2 0.7433 2.7382 0.7275 28.7072
L-1236 GDSC1 0.7826 5.3464 0.138 45.7147
L-540 GDSC1; CTRP2 0.8067 3.7223 0.7021 28.5849
IM-9 GDSC1 0.8801 2.8915 0.8385 43.2073
ROS-50 GDSC1 0.8916 6.0664 -0.0095 45.0943
ME1 GDSC1 0.9588 5.2808 0.3514 43.9033
Ci-1 CTRP2 0.9717 3.3352 0.924 27.2931
CTV-1 GDSC1 1.003 3.3556 0.9106 41.9086
MEG-01 GDSC1 1.0132 4.2101 0.741 42.4304
U-937 CTRP2 1.0189 3.0954 0.9926 26.9068
SET-2 CTRP2 1.0273 4.1425 0.8696 27.2984
PL21 CTRP2 1.0634 6.3093 0.2988 29.1157
EHEB GDSC1 1.0852 4.2722 0.8031 41.6408
MHH-CALL-4 CTRP2 1.1211 4.8671 0.8099 27.2045
KY821 GDSC1 1.1692 4.0567 0.9499 40.4306
Mono-Mac-6 GDSC1; CTRP2 1.1694 6.8619 0.21 29.0729
A3/Kawakami GDSC1; CTRP2 1.1856 2.2701 1.1852 25.7092
OCI-Ly19 GDSC1; CTRP2 1.1999 3.3528 1.1619 25.74
HuNS1 CTRP2 1.2125 8.0207 -0.2063 30.2388
HEL GDSC1 1.2175 3.0662 1.1765 39.0333
K-562 GDSC1; CTRP2 1.2512 6.4195 0.4619 27.9868
F-36P CTRP2 1.2533 6.1845 0.5479 27.6899
AMO1 GDSC1; CTRP2 1.2591 3.4682 1.2136 25.3715
U266B1 GDSC1; CTRP2 1.2727 4.6448 1.0301 25.961
SU-DHL-1 GDSC1 1.312 2.5676 1.3061 37.6596
RL GDSC1; CTRP2 1.343 5.1002 0.9896 25.8818
SK-MM-2 GDSC1 1.3683 6.4372 0.3485 40.9263
Karpas-299 GDSC1; CTRP2 1.4246 5.2981 1.0219 25.515
ARH-77 GDSC1 1.4608 4.3558 1.1902 37.2121
RC-K8 GDSC1 1.4646 4.0925 1.2632 36.8268
SEM CTRP2 1.5073 3.5494 1.4668 23.7011
OCI-AML-2 GDSC1; CTRP2 1.514 9.894 -0.7119 30.7791
SIG-M5 GDSC1; CTRP2 1.5168 5.2835 1.1267 24.8605
HD-MY-Z CTRP2 1.5424 5.4856 1.0936 24.8994
OCI-Ly3 CTRP2 1.5577 4.671 1.3344 23.9992
SKM-1 GDSC1; CTRP2 1.6605 3.1395 1.6517 22.5734
L-428 GDSC1; CTRP2 1.7007 4.1258 1.5989 22.6228
DG-75 GDSC1 1.721 5.7554 0.9948 36.3139
DND-41 GDSC1; CTRP2 1.7641 7.7357 0.4897 26.3518
MOTN-1 CTRP2 1.7706 6.3955 1.0292 24.4435
SCC-3 GDSC1 1.8004 3.1234 1.7824 31.6313
MOLP-2 CTRP2 1.8495 9.8195 -0.3404 28.7513
HDLM-2 GDSC1 1.8896 4.94 1.4762 32.8673
TF-1 CTRP2 1.8898 4.622 1.7071 21.6468
KM-H2 GDSC1 1.9808 4.3375 1.7627 30.6278
Granta-519 GDSC1; CTRP2 2.0663 7.0699 1.0817 23.3952
MOLM-6 CTRP2 2.1277 5.8531 1.6088 21.2828
M-07e CTRP2 2.1291 7.1603 1.1111 23.1097
WSU-NHL GDSC1 2.1407 4.5167 1.8856 28.8913
MOLT-13 GDSC1; CTRP2 2.1746 6.9509 1.2443 22.4926
HuT 78 CTRP2 2.3255 7.5533 1.1515 22.4117
HEL 92.1.7 CTRP2 2.5106 7.9329 1.1775 21.8093
P31/FUJ GDSC1 2.5144 5.0608 2.1077 25.2888
KO52 CTRP2 2.53 5.1409 2.2734 17.6521
JVM-3 GDSC1 2.59 4.5589 2.3622 23.1527
P3HR-1 CTRP2 3.1235 12.3336 -0.3031 25.2784
MHH-CALL-3 CTRP2 3.2641 7.7747 2.0121 16.6358
OCI-Ly10 CTRP2 3.292 7.5569 2.1394 16.0622
ME1 CTRP2 3.3672 7.1566 2.3959 14.8538
Raji GDSC1; CTRP2 3.7891 10.8172 1.0551 19.0727
CMK CTRP2 3.9365 9.5795 1.7983 15.8687
WSU-DLCL2 GDSC1 4.097 7.7094 2.4373 15.5175
JVM-2 GDSC1 4.5453 13.7799 -0.2222 28.092
Toledo CTRP2 5.0107 11.1756 1.9507 12.9795
MJ CTRP2 5.3864 9.3543 3.1674 7.2513
⏷ Show the Full List of 194 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 0.7238 6.7119 -0.2121 31.8124
TE-5 GDSC1; CTRP2 -1.5762 2.2544 -1.6527 44.2708
TE-6 GDSC1 -1.4899 2.0912 -1.5796 68.4887
TE-8 GDSC1 -0.9428 6.2312 -2.0386 58.5557
TE-10 GDSC1 -0.9237 1.6894 -0.9522 64.3506
TE-15 GDSC1 -0.8608 3.6922 -1.1754 60.9052
KYSE-270 GDSC1 -0.126 2.8553 -0.2247 55.0328
TE-9 GDSC1 0.0019 2.7196 -0.0711 53.6939
EC-GI-10 GDSC1; CTRP2 0.003 3.667 -0.1518 34.086
OE21 GDSC1; CTRP2 0.409 3.0462 0.3596 31.0464
KYSE-520 GDSC1; CTRP2 0.4207 4.3265 0.1747 31.6172
KYSE-140 GDSC1 0.727 3.9779 0.487 45.5784
KYSE-410 GDSC1; CTRP2 0.76 4.6721 0.4649 29.538
COLO 680N GDSC1 0.8412 4.0472 0.5947 44.309
TE-11 GDSC1; CTRP2 1.1404 3.57 1.0775 26.2212
TE-4 GDSC1 1.2082 3.2116 1.1501 39.2367
OE33 GDSC1; CTRP2 1.2208 6.079 0.5493 27.786
KYSE-30 CTRP2 1.256 5.5368 0.7657 26.9339
KYSE-180 GDSC1 1.3021 5.0199 0.8123 39.9438
KYSE-150 GDSC1; CTRP2 1.3028 4.7038 1.0488 25.8008
TE-14 CTRP2 2.0585 6.0832 1.4529 22.0588
KYSE-70 GDSC1; CTRP2 2.1263 5.2578 1.799 20.5914
T.T GDSC1 2.3692 6.1241 1.5259 29.7114
TE-1 GDSC1; CTRP2 2.5386 8.2404 1.0694 22.1328
KYSE-450 GDSC1; CTRP2 2.8596 9.481 0.8184 22.202
KYSE-510 GDSC1; CTRP2 3.021 8.6564 1.3631 19.7726
OE19 GDSC1; CTRP2 4.854 12.5674 1.1231 16.513
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 1.828 6.8724 0.9083 24.707
KP-4 GDSC1 -0.9119 3.759 -1.2466 61.1995
MZ-PC-1 GDSC1 -0.8863 2.0729 -0.9415 63.4563
HuP-T4 GDSC1; CTRP2 -0.6528 2.5038 -0.7062 38.1203
SUIT-2 GDSC1 -0.4499 1.905 -0.4746 59.1596
BxPC-3 GDSC1 0.0822 2.8908 -0.0073 52.7436
HPAF-II GDSC1 0.2042 6.4978 -0.909 50.8874
Panc 08.13 GDSC1; CTRP2 0.3589 5.4097 -0.1733 32.9198
Panc 03.27 GDSC1; CTRP2 0.4199 3.6838 0.2934 31.2301
QGP-1 GDSC1 0.5632 4.9872 0.0207 47.7125
HPAC GDSC1; CTRP2 0.7253 6.3444 -0.0788 31.4043
PL4 GDSC1 0.9458 5.8853 0.1175 44.4714
DAN-G GDSC1; CTRP2 0.9916 3.8894 0.8748 27.3957
PaTu 8988t GDSC1 1.1274 6.5827 0.0354 43.3161
MIA PaCa-2 GDSC1; CTRP2 1.3307 4.4977 1.1267 25.4408
Capan-2 GDSC1; CTRP2 1.4745 6.1295 0.8062 26.1206
Panc 05.04 CTRP2 1.5311 12.9321 -2.1073 34.0295
PaTu 8988s CTRP2 1.5437 4.9985 1.2364 24.3888
Capan-1 GDSC1; CTRP2 1.5464 5.7266 1.021 25.1452
Panc 04.03 GDSC1; CTRP2 1.6868 4.9596 1.403 23.3549
PK-59 CTRP2 1.7667 7.7821 0.473 26.4012
CFPAC-1 GDSC1 1.866 5.0679 1.4064 33.3961
PSN1 GDSC1; CTRP2 1.9045 5.4197 1.5083 22.3132
Panc 02.03 GDSC1; CTRP2 1.9752 7.8466 0.6627 25.1481
KP-1N GDSC1 2.022 5.6507 1.3558 32.6855
SW1990 GDSC1; CTRP2 2.0894 7.0644 1.1084 23.2323
HuP-T3 GDSC1; CTRP2 2.1138 6.5365 1.3433 22.3017
SU.86.86 GDSC1 2.2288 5.7725 1.5259 30.5214
AsPC-1 GDSC1; CTRP2 2.5392 7.4412 1.421 20.8222
KP-3 GDSC1 2.5434 7.2198 1.2144 30.4204
L3.3 CTRP2 2.6797 7.2811 1.6354 19.6287
Panc 10.05 GDSC1; CTRP2 2.7116 8.1844 1.2698 20.9277
KP-2 CTRP2 2.9481 8.2199 1.4919 19.468
TCC-Pan2 CTRP2 3.029 8.2194 1.573 18.9485
PK-45H CTRP2 3.0302 11.4784 0.0259 24.4759
Hs 766T GDSC1; CTRP2 3.4305 9.4682 1.3766 18.7044
PaTu 8902 GDSC1; CTRP2 3.4569 7.0951 2.5145 14.153
YAPC GDSC1; CTRP2 4.5707 10.8844 1.7208 14.7913
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 74 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.3459 11.3594 2.1345 13.3273
MMAc-SF GDSC1 -6.4631 3.8139 -7.3134 79.8824
CP50-MEL-B GDSC1 -6.0266 0.3985 -6.1917 87.5173
CHL-1 GDSC1 -5.8778 2.1323 -6.2971 82.8145
WM35 GDSC1 -5.1238 -0.3644 -5.1784 89.1311
RPMI-7951 GDSC1 -4.5956 7.6133 -6.4725 70.0709
Mel Ho GDSC1 -4.4789 0.8586 -4.6052 84.3473
A101D GDSC1 -4.4192 3.8485 -5.0925 76.1984
A-431 GDSC1 -4.3025 -1.2813 -4.3077 91.5823
MZ-MEL-2 GDSC1 -4.242 1.2959 -4.4052 82.5265
DJM-1 GDSC1 -4.145 3.4536 -4.6965 76.4402
VMRC-MELG GDSC1 -4.081 -0.3178 -4.1062 87.689
WM278 GDSC1 -3.822 11.9337 -7.3797 63.7314
G-mel GDSC1 -3.47 -1.4606 -3.4704 90.7045
MZ-MEL-7 GDSC1 -3.4164 1.7373 -3.5835 79.0592
SK-MEL-28 GDSC1; CTRP2 -3.2826 22.602 -11.3679 51.6868
M14 GDSC1 -2.9913 3.803 -3.5238 72.1486
COLO 783 GDSC1 -2.8939 5.565 -3.9244 68.3638
WM1552C GDSC1 -2.7466 1.4141 -2.8351 77.6223
WM115 GDSC1; CTRP2 -2.63 1.0148 -2.6621 51.1035
451Lu GDSC1 -2.4219 3.0346 -2.7306 71.6388
Hs 938.T GDSC1 -2.3365 8.2652 -4.3031 62.7634
SH-4 GDSC1 -1.9426 1.9132 -2.0388 71.9791
LB373-MEL-D GDSC1 -1.9292 7.211 -3.4607 62.3339
HMV-II GDSC1 -1.378 3.5657 -1.7096 64.7542
IST-MEL1 GDSC1 -1.3017 6.0547 -2.3627 60.7117
COLO 679 GDSC1 -1.1839 3.64 -1.5152 63.3298
A-388 GDSC1 -1.155 1.0753 -1.1642 67.5041
LB2518-MEL GDSC1 -1.1345 2.6111 -1.268 64.7329
WM266-4 CTRP2 -0.8965 2.6501 -0.9759 39.8076
SK-MEL-2 GDSC1; CTRP2 -0.8075 2.0073 -0.8338 39.0673
A2058 GDSC1 -0.6401 7.6296 -2.2532 55.8253
SK-MEL-5 GDSC1; CTRP2 -0.5573 3.4505 -0.7191 37.8003
MeWo GDSC1; CTRP2 -0.4387 3.786 -0.6489 37.1587
COLO 792 GDSC1 -0.2122 2.309 -0.2554 56.2662
SK-MEL-24 GDSC1; CTRP2 -0.0504 2.9353 -0.1129 34.147
GAK GDSC1 -0.0386 5.953 -0.9643 52.815
SK-MEL-1 GDSC1 0.1317 12.726 -3.7339 50.7977
CP66-MEL GDSC1 0.1679 3.5649 -0.0295 51.6553
WM88 CTRP2 0.4257 3.3077 0.3504 31.0216
Hs 940.T GDSC1; CTRP2 0.4501 7.5905 -0.8381 34.461
HT-144 GDSC1; CTRP2 0.5483 4.0868 0.362 30.5767
G-361 GDSC1; CTRP2 0.8065 5.7668 0.2038 30.2478
RVH-421 GDSC1; CTRP2 0.9798 6.9504 -0.0264 30.4197
A-375 GDSC1; CTRP2 0.9866 8.4859 -0.6369 32.1783
SK-MEL-3 GDSC1; CTRP2 1.0066 6.1629 0.2886 29.3295
COLO 829 GDSC1; CTRP2 1.1816 10.3262 -1.2428 33.1287
Hs 852.T CTRP2 1.182 7.391 0.0177 29.6462
WM983B CTRP2 1.2236 5.2603 0.8137 26.8683
Hs 294T CTRP2 1.2988 5.146 0.9285 26.2334
IGR-1 GDSC1; CTRP2 1.3326 3.3664 1.2996 24.8393
UACC-62 GDSC1; CTRP2 1.4031 5.1287 1.0472 25.4928
LOX-IMVI GDSC1; CTRP2 1.4236 4.3656 1.2554 24.6981
WM1799 CTRP2 1.4361 8.1397 -0.0224 28.9941
CJM [Human melanoma] CTRP2 1.5008 4.9161 1.2114 24.6101
COLO 800 GDSC1; CTRP2 1.5434 10.1553 -0.8008 30.9336
Hs 944.T CTRP2 1.564 6.8561 0.6337 26.4501
Hs 895.T CTRP2 1.6518 7.6488 0.4085 26.9553
IGR-39 CTRP2 1.6967 9.5591 -0.3762 29.2953
IPC-298 GDSC1; CTRP2 1.9176 4.3482 1.7938 21.2547
IGR-37 GDSC1; CTRP2 2.0274 5.6342 1.5738 21.7073
SK-MEL-30 GDSC1; CTRP2 2.1449 4.1959 2.0648 19.5892
WM793 GDSC1; CTRP2 2.3944 11.1558 -0.4269 27.5104
MDA-MB-435S CTRP2 2.4635 8.6385 0.8142 23.2597
UACC-257 GDSC1; CTRP2 2.5574 8.8098 0.8307 22.9491
Hs 934.T CTRP2 3.1078 8.8809 1.3436 19.6266
Hs 688(A).T CTRP2 3.1594 9.5882 1.059 20.5659
Mel JuSo GDSC1; CTRP2 3.232 9.7081 1.0714 20.3402
Hs 839.T CTRP2 3.2563 11.4064 0.2732 23.106
WT2-iPS GDSC1; CTRP2 3.7534 8.0426 2.369 14.0017
SK-MEL-31 CTRP2 3.9402 10.4345 1.3816 17.4912
K029AX CTRP2 4.2128 10.2358 1.7268 15.5343
Malme-3M CTRP2 4.669 17.2949 -1.3965 24.9195
Hs 936.T CTRP2 5.2244 15.9051 -0.2367 20.4609
⏷ Show the Full List of 74 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC1 -1.3471 1.2853 -1.368 68.9937
TE-12 GDSC1 -1.1699 10.311 -3.94 56.7687
ESO-26 GDSC1 -0.5484 2.5928 -0.6402 59.5645
KYSE-50 GDSC1 -0.2873 2.3736 -0.34 57.0545
KYAE-1 GDSC1 -0.0853 2.6593 -0.1566 54.6864
OACM5.1 C GDSC1 -0.0086 4.2368 -0.3811 53.2027
FLO-1 GDSC1 0.0567 4.2502 -0.3135 52.5878
SK-GT-4 GDSC1 0.5399 4.2046 0.226 47.7298
KYSE-220 GDSC1 0.6638 4.0509 0.4003 46.3246
HCE-4 GDSC1 0.9861 5.1841 0.4142 43.5451
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 -1.7374 5.4461 -2.4703 46.0686
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-5 GDSC1 -5.9047 9.2916 -8.5025 70.6293
SK-N-SH GDSC1 -5.1028 -0.5803 -5.1446 89.8224
NB69 GDSC1 -5.0703 0.1832 -5.1626 87.3184
GI-ME-N GDSC1 -4.9346 4.7421 -5.8978 75.4853
SK-N-BE(2)-M17 GDSC1 -4.466 -0.4283 -4.4966 88.6704
SJNB-10 GDSC1 -4.4365 -0.6489 -4.4578 89.4206
SJNB-5 GDSC1 -4.407 1.7193 -4.6406 81.5914
SK-N-MC-IXC GDSC1 -4.256 -1.811 -4.257 93.5129
NH-12 GDSC1 -3.6511 2.044 -3.8799 78.8347
NB1 GDSC1; CTRP2 -3.3114 -2.6827 -3.3114 55.6677
KP-N-YS GDSC1 -3.2748 -0.3168 -3.2843 85.6867
SJNB-17 GDSC1 -2.9311 1.3516 -3.0232 78.5814
NB(TU)1 GDSC1 -2.5484 3.418 -2.9497 71.2842
CHP-212 GDSC1; CTRP2 -2.4934 0.3048 -2.5002 50.2166
SJNB-14 GDSC1 -2.4367 0.3929 -2.4502 79.3662
GOTO GDSC1 -1.6589 3.2124 -1.9391 67.1981
CHP-134 GDSC1 -1.443 1.9895 -1.5191 68.3562
SJNB-13 GDSC1 -1.3574 2.2573 -1.4585 67.1435
SiMa GDSC1 -1.318 2.4027 -1.435 66.5509
LA-N-6 GDSC1 -1.2344 3.6804 -1.5795 63.6076
Kelly GDSC1; CTRP2 -1.0639 3.8404 -1.3359 41.3548
SJNB-12 GDSC1 -0.968 1.9947 -1.0203 64.3343
IMR-32 CTRP2 -0.9514 1.4536 -0.9605 39.9736
MHH-NB-11 GDSC1 -0.7625 2.6737 -0.8792 61.4813
SK-N-FI GDSC1; CTRP2 -0.4768 3.5544 -0.6494 37.3021
SJNB-7 GDSC1 -0.1466 1.8355 -0.1593 55.7134
KP-N-YN GDSC1; CTRP2 0.3335 4.0424 0.1381 32.029
KP-N-SI9s CTRP2 0.7362 7.9458 -0.6764 33.0878
SJNB-6 GDSC1 0.9052 5.3064 0.2845 44.468
SK-N-AS GDSC1; CTRP2 1.0166 4.2204 0.8432 27.4232
SK-N-BE(2) CTRP2 1.0274 5.3377 0.5771 28.2998
SK-N-DZ GDSC1; CTRP2 1.3067 4.1295 1.1737 25.3544
NH-6 CTRP2 1.344 6.0158 0.7044 26.8735
CHP-126 CTRP2 2.9687 8.0032 1.6113 18.9564
TGW GDSC1 4.6461 9.3311 2.0821 15.9935
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 -0.4872 2.3378 -0.5468 59.2008
SNU-869 CTRP2 4.6394 12.4441 1.0019 17.4058
Cancer Drug Sensitivity Data Curated from 88 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EFM-19 GDSC1 -3.2251 4.8909 -4.0765 70.7056
UACC-893 GDSC1 -2.3341 -0.2207 -2.336 80.5556
HCC1954 GDSC1 -2.1141 2.9435 -2.3793 70.3574
OCUB-M GDSC1 -2.0761 -0.4241 -2.0764 78.9226
HCC1187 GDSC1 -2.0693 1.0934 -2.1029 75.0103
HCC1599 GDSC1 -1.6713 -0.2176 -1.6715 74.5275
Hs 578T GDSC1; CTRP2 -1.5053 2.9881 -1.6651 43.962
MDA-MB-361 GDSC1; CTRP2 -1.4619 2.4052 -1.5472 43.5403
MRK-nu-1 GDSC1 -1.4016 0.9235 -1.411 70.1472
EFM-192A GDSC1; CTRP2 -1.3239 2.8198 -1.4485 42.7205
CAL-148 GDSC1 -1.0391 0.8201 -1.0421 66.5736
MDA-MB-175-VII GDSC1 -0.9524 4.7216 -1.548 60.2261
MDA-MB-330 GDSC1 -0.9402 4.6557 -1.5153 60.2258
HCC70 GDSC1 -0.8943 1.2016 -0.9023 64.6258
BT-20 GDSC1; CTRP2 -0.7616 2.2505 -0.8008 38.8008
HCC2157 GDSC1 -0.5744 2.2493 -0.6301 60.1811
DU4475 GDSC1; CTRP2 -0.5155 2.2599 -0.5461 37.1387
HCC1143 CTRP2 -0.5045 3.9511 -0.7516 37.6892
SK-BR-3 CTRP2 -0.4826 1.9287 -0.4968 36.8678
AU565 GDSC1; CTRP2 -0.3664 3.6865 -0.553 36.6175
CAMA-1 GDSC1 -0.3651 3.948 -0.6962 56.5803
COLO 824 GDSC1 -0.2301 2.8663 -0.3374 56.1211
MDA-MB-453 GDSC1; CTRP2 -0.23 3.1763 -0.33 35.4581
CAL-120 GDSC1 -0.0609 7.108 -1.4313 52.612
CAL-85-1 GDSC1; CTRP2 0.0535 4.5543 -0.2767 34.2923
MDA-MB-415 GDSC1 0.0707 3.3735 -0.0973 52.7289
MFM-223 GDSC1 0.1141 2.3665 0.0808 52.4945
HCC1806 GDSC1 0.1999 3.039 0.0977 51.3928
HCC1569 GDSC1 0.2566 4.6964 -0.2223 50.6182
HCC1419 GDSC1; CTRP2 0.5158 5.7333 -0.1017 32.1703
HCC202 GDSC1; CTRP2 0.5292 6.4033 -0.3113 32.7517
Evsa-T GDSC1 0.6272 5.8498 -0.2106 47.3817
BT-549 GDSC1; CTRP2 0.6788 5.1178 0.2599 30.4828
BT-483 GDSC1 0.8243 114.5813 -53.7489 49.7576
MCF-7 GDSC1 0.8293 5.5666 0.1103 45.3833
MDA-MB-436 GDSC1 0.8451 5.7968 0.0428 45.3666
HDQ-P1 GDSC1 0.8465 5.6826 0.0866 45.2862
T-47D GDSC1; CTRP2 0.9047 7.4648 -0.3056 31.5015
MDA-MB-157 GDSC1; CTRP2 0.9411 4.119 0.7808 27.8805
HCC1937 GDSC1 1.009 5.495 0.3297 43.5601
BT-474 GDSC1; CTRP2 1.0505 4.9976 0.6985 27.8118
HCC38 GDSC1; CTRP2 1.0824 5.1202 0.6997 27.7065
CAL-51 GDSC1; CTRP2 1.168 6.4122 0.375 28.536
YMB-1-E GDSC1 1.1897 6.4482 0.1559 42.6289
MDA-MB-468 GDSC1; CTRP2 1.3632 4.4753 1.1669 25.198
HCC2218 GDSC1; CTRP2 1.6704 6.122 1.0204 24.7732
HCC1500 GDSC1; CTRP2 1.8579 10.2316 -0.5211 29.2545
HCC1428 GDSC1; CTRP2 1.9183 8.0033 0.5367 25.7461
ZR-75-1 CTRP2 1.9194 7.6587 0.6843 25.2322
ZR-75-30 GDSC1; CTRP2 2.094 7.4344 0.9607 23.7543
HCC1395 GDSC1 2.1262 5.6129 1.4814 31.3786
MDA-MB-231 GDSC1; CTRP2 2.3263 7.5286 1.163 22.3672
Hs 578Bst CTRP2 3.606 8.7089 1.9089 16.2016
UACC-812 GDSC1 3.6123 8.1786 1.7744 22.051
BT 416 CTRP2 -0.8353 0.5815 -0.8354 39.1716
BT 239 CTRP2 -0.695 4.0061 -0.9693 38.994
BT 145 CTRP2 -0.1597 4.3708 -0.4663 35.6119
BT 231 CTRP2 0.4955 7.12 -0.6088 33.7032
BT 248 CTRP2 1.1027 5.8546 0.497 28.3328
BT 139 CTRP2 1.2821 7.3509 0.1398 28.95
BT164 CTRP2 1.2929 5.7014 0.7537 26.8607
BT 179 CTRP2 1.5504 8.5896 -0.0964 28.882
BT 330 CTRP2 1.6137 7.1237 0.5816 26.4809
BT 228 CTRP2 1.7286 9.2076 -0.186 28.6346
BT 159 CTRP2 1.7391 8.9045 -0.0406 28.1555
BT 286 CTRP2 1.7605 6.8932 0.8284 25.1876
BT 271 CTRP2 1.775 6.9978 0.8026 25.2362
BT 112 CTRP2 1.8671 7.1748 0.8291 24.8742
BT 482 CTRP2 1.8819 6.825 0.9842 24.2787
BT 172 CTRP2 1.9495 8.4087 0.3932 26.1437
BT 440 CTRP2 2.2332 8.7667 0.5236 24.9062
BT 504 CTRP2 2.4789 8.715 0.795 23.2868
BT 359 CTRP2 2.7119 11.484 -0.2787 26.2365
BT 245 CTRP2 2.7757 7.7597 1.525 19.7927
BT 224 CTRP2 2.9479 9.9023 0.7049 22.382
BT 187 CTRP2 3.5482 11.2152 0.6379 21.1493
BT 333 CTRP2 3.886 11.2062 0.9518 19.2327
BT 320 CTRP2 3.9381 10.3084 1.4418 17.2637
BT147 CTRP2 4.1753 12.3971 0.6209 19.779
BT 428 CTRP2 4.2329 7.8361 2.9256 10.6052
BT 232 CTRP2 4.2797 10.6927 1.5601 16.0445
BT 340 CTRP2 4.7397 11.7527 1.4331 15.5671
BT 422 CTRP2 4.8481 12.4911 1.1562 16.4009
BT 328 CTRP2 4.8702 11.2097 1.8155 13.8002
BT 444 CTRP2 4.9869 10.9749 2.0311 12.7023
BT 216 CTRP2 5.3298 11.654 1.9743 12.2702
BT 131 CTRP2 5.5241 11.2432 2.3351 10.4501
BT 498 CTRP2 6.5565 8.4691 4.3676 0.9403
⏷ Show the Full List of 88 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PFSK-1 GDSC1 -1.737 1.5637 -1.7893 71.5095
YH-13 GDSC1 -1.62 1.0141 -1.6368 71.9032
GI-1 GDSC1 -1.0612 1.2813 -1.0748 66.2765
AM-38 GDSC1 -0.9863 2.0217 -1.0418 64.4611
MOG-G-CCM GDSC1 -0.9124 1.8172 -0.9486 64.0654
D283 Med GDSC1; CTRP2 -0.8212 2.4435 -0.8774 39.2455
GB-1 GDSC1 -0.5238 3.0228 -0.6767 58.8765
D-336MG GDSC1 -0.5173 1.7282 -0.5351 60.035
CAS-1 GDSC1 -0.4181 3.0277 -0.5638 57.8721
D-502MG GDSC1 -0.3882 2.1934 -0.4301 58.2736
Daoy GDSC1 -0.3695 2.931 -0.4962 57.4833
KS-1 [Human Krukenberg tumour] GDSC1 -0.3575 2.3115 -0.408 57.8556
D-542MG GDSC1 -0.3199 2.6652 -0.4063 57.195
M059J GDSC1 -0.1795 2.3778 -0.2272 55.8659
MOG-G-UVW GDSC1 -0.1789 3.6583 -0.426 55.0976
SF126 GDSC1 -0.1652 2.4113 -0.2152 55.69
D-263MG GDSC1 -0.1454 2.1442 -0.1736 55.5874
SF539 GDSC1; CTRP2 -0.1159 3.0229 -0.191 34.6224
D-247MG GDSC1 -0.0906 2.2504 -0.1239 54.9145
NMC-G1 GDSC1 -0.053 2.184 -0.0804 54.5022
D-423MG GDSC1 0.0038 3.6201 -0.2192 53.3305
KNS-81-FD GDSC1 0.0147 4.3772 -0.3939 52.9344
D-566MG GDSC1 0.0178 1.8974 0.0067 53.7298
H4 GDSC1 0.0534 2.5905 -0.0025 53.1511
KINGS-1 GDSC1 0.1151 2.8845 0.0286 52.3764
Hs 683 GDSC1; CTRP2 0.1304 2.6219 0.1011 32.835
DK-MG GDSC1; CTRP2 0.1426 4.11 -0.082 33.3835
LN-18 GDSC1 0.2367 3.5953 0.0389 50.9206
U-251MG GDSC1; CTRP2 0.2495 4.3093 -0.0075 32.7814
8-MG-BA GDSC1 0.2591 2.6719 0.2061 50.7454
LN-405 GDSC1 0.2698 3.3283 0.126 50.5818
YKG-1 GDSC1; CTRP2 0.3763 3.6831 0.2466 31.5304
SNB-75 GDSC1; CTRP2 0.4178 5.3551 -0.0929 32.4743
Onda 11 GDSC1 0.4212 4.1129 0.1202 48.9692
LNZTA3WT4 GDSC1 0.4488 2.6663 0.4062 48.4734
ONS-76 GDSC1 0.4663 3.1439 0.3675 48.3259
GaMG GDSC1; CTRP2 0.4677 6.414 -0.3816 33.1631
U-87MG ATCC GDSC1 0.4725 4.5618 0.0531 48.511
42-MG-BA GDSC1; CTRP2 0.5743 4.2027 0.3674 30.4727
SF268 GDSC1; CTRP2 0.733 4.138 0.5521 29.3328
LN-229 GDSC1 0.7724 3.6085 0.6171 44.8637
D-392MG GDSC1 0.808 4.0156 0.5662 44.6725
SW1783 GDSC1; CTRP2 0.8347 4.4684 0.5937 28.8615
KG-1-C CTRP2 0.8887 5.7352 0.3033 29.6579
Becker GDSC1; CTRP2 1.0348 5.2151 0.6208 28.1276
SW1088 GDSC1; CTRP2 1.1393 6.3996 0.3485 28.7138
SF295 GDSC1 1.3417 4.0469 1.1403 38.3037
U-118MG GDSC1; CTRP2 1.3685 6.3482 0.614 27.1095
Onda 10 GDSC1 1.4382 4.0045 1.2555 37.0519
DBTRG-05MG GDSC1; CTRP2 1.4837 6.9574 0.5088 27.1183
KALS-1 GDSC1; CTRP2 1.9935 7.2204 0.9438 24.1013
SK-MG-1 GDSC1 2.0028 6.1535 1.1315 33.9178
A-172 GDSC1; CTRP2 2.2869 6.7358 1.4493 21.416
T98G GDSC1; CTRP2 2.3448 4.7201 2.18 18.555
KNS-42 GDSC1; CTRP2 2.4296 6.2732 1.7814 19.7685
CCF-STTG1 CTRP2 3.8269 11.2591 0.872 19.6599
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 -0.5336 3.4243 -0.7617 58.543
ETK-1 GDSC1 0.0576 2.1291 0.0374 53.2089
TGBC1TKB GDSC1 1.359 5.2187 0.8057 39.5517
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC1 -2.9908 1.4295 -3.0942 78.5636
RL95-2 GDSC1 -2.3675 1.8254 -2.4788 74.6012
AN3-CA GDSC1; CTRP2 -1.3446 2.4101 -1.424 42.7589
JHUEM-7 CTRP2 -0.5233 4.7883 -0.9638 38.3063
JHUEM-3 CTRP2 0.0969 4.4828 -0.2127 33.9464
JHUEM-1 CTRP2 0.5117 2.955 0.4746 30.3217
ESS-1 GDSC1; CTRP2 0.8028 6.5361 -0.0633 31.1032
MFE-296 GDSC1; CTRP2 1.0452 4.4167 0.8339 27.3636
MFE-319 GDSC1; CTRP2 1.1304 3.6912 1.052 26.3403
HEC-1-A CTRP2 1.2801 6.8984 0.3145 28.3883
KLE GDSC1 1.7584 12.138 -1.8848 42.868
EN GDSC1; CTRP2 1.8926 6.0311 1.2925 23.1319
HEC-151 CTRP2 2.8885 5.5993 2.5196 15.6829
EFE-184 CTRP2 2.917 8.3374 1.407 19.8725
HEC-50B CTRP2 3.7548 9.948 1.4495 17.6552
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB996-RCC GDSC1 -1.8916 0.5104 -1.899 75.2799
KTCTL-21 GDSC1 -1.3561 1.8299 -1.4127 68.0037
KTCTL-1M GDSC1 -1.3047 1.5159 -1.3363 68.186
KTCTL-140 GDSC1 -1.1658 2.1859 -1.2472 65.7528
KTCTL-13 GDSC1 -1.0491 2.1356 -1.1186 64.8413
KTCTL-26A GDSC1 -0.9856 1.521 -1.0071 65.1929
NCC021 GDSC1 -0.802 1.9578 -0.8438 62.7976
KTCTL-195 GDSC1 -0.7262 5.2633 -1.4703 58.1315
HA7-RCC GDSC1 -0.1671 3.1349 -0.3115 55.3035
LB1047-RCC GDSC1 -0.1319 2.5944 -0.1986 55.2295
CAL-54 GDSC1; CTRP2 0.0517 3.3659 -0.0546 33.6091
SW13 GDSC1 0.1329 2.7911 0.0593 52.1954
LB2241-RCC GDSC1 0.2864 3.5057 0.1108 50.3895
769-P GDSC1 0.396 3.1329 0.2938 49.1456
SN12C GDSC1 0.4219 4.5688 -0.0042 49.0188
VMRC-RCZ GDSC1; CTRP2 0.5174 3.7778 0.3832 30.6083
UO-31 GDSC1; CTRP2 0.6291 6.2534 -0.1511 31.9419
KMRC-2 CTRP2 0.7247 4.4283 0.483 29.5926
Caki-1 GDSC1; CTRP2 0.9016 3.5941 0.821 27.8716
TK-10 GDSC1 0.9037 4.2189 0.6191 43.7063
BB65-RCC GDSC1 0.949 4.809 0.4972 43.6437
BFTC-909 GDSC1 1.0874 5.6278 0.3656 42.8813
Caki-2 CTRP2 1.4249 22.4135 -6.8146 40.4369
KMRC-1 GDSC1; CTRP2 1.4395 5.2607 1.0492 25.3728
OS-RC-2 GDSC1 1.6222 7.6272 0.1009 39.9712
786-O GDSC1; CTRP2 1.7755 4.953 1.5015 22.7307
SW156 GDSC1 1.9081 5.4093 1.3274 33.5416
KMRC-20 GDSC1 1.9602 6.7201 0.8463 35.4339
VMRC-RCW GDSC1; CTRP2 2.0861 5.7617 1.5951 21.4554
ACHN GDSC1; CTRP2 2.2953 7.0183 1.3441 21.7835
TUHR10TKB CTRP2 2.3136 8.7621 0.607 24.3972
RXF 393L GDSC1 2.322 4.9463 1.9418 27.4659
A-704 GDSC1 2.4254 3.6878 2.3846 23.9658
KMRC-3 CTRP2 2.6036 9.3446 0.6302 23.5369
RCC10RGB GDSC1; CTRP2 3.0944 10.9679 0.3337 23.3003
A-498 GDSC1; CTRP2 4.247 8.8446 2.4448 12.5546
TUHR14TKB CTRP2 5.2545 10.9715 2.254 11.2798
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 GDSC1 -3.5245 6.4136 -4.8915 69.0299
GP2d CTRP2 -1.9309 2.5556 -2.0609 46.647
LoVo GDSC1; CTRP2 -1.1917 4.0541 -1.5186 42.2739
SNU-175 GDSC1 -0.8616 4.5541 -1.4 59.8132
NCI-H747 GDSC1; CTRP2 -0.5596 4.1211 -0.8463 38.1515
GP5d GDSC1 -0.4992 2.333 -0.559 59.3293
CaR-1 GDSC1 -0.1032 3.4142 -0.2933 54.4999
CCK-81 GDSC1; CTRP2 -0.0491 4.4035 -0.3533 34.884
COLO 320 CTRP2 0.1428 3.6743 -0.0027 33.1311
COLO 320HSR GDSC1 0.3155 5.1929 -0.3159 50.0576
LS180 GDSC1 0.318 6.0076 -0.6011 50.0319
C2BBe1 GDSC1; CTRP2 0.4512 7.5968 -0.8394 34.4602
SW837 GDSC1 0.5345 3.4806 0.3842 47.5994
SW948 GDSC1; CTRP2 0.5622 4.0704 0.3802 30.4697
SNU-C1 GDSC1; CTRP2 0.6375 5.0259 0.24 30.6835
HT-29 GDSC1 0.6748 3.5635 0.5201 45.9955
HT115 GDSC1 0.8065 4.0094 0.5661 44.6857
HCT 15 GDSC1; CTRP2 0.8548 5.2532 0.4135 29.4026
SNU-C2B GDSC1 0.9102 4.6926 0.4912 43.9772
HT-55 GDSC1; CTRP2 1.048 7.498 -0.1668 30.6333
COLO205 GDSC1 1.077 3.0242 1.0326 40.7911
LS513 GDSC1 1.1117 4.9843 0.6175 42.0236
T84 GDSC1; CTRP2 1.1197 5.9412 0.4866 28.3141
MDST8 GDSC1; CTRP2 1.1389 5.0815 0.772 27.2788
HCT 116 GDSC1 1.1967 4.2795 0.9228 40.3256
SNU-407 GDSC1; CTRP2 1.273 6.7154 0.3762 28.2064
SNU-C5 GDSC1; CTRP2 1.4599 8.3294 -0.0781 29.0955
SNU-1040 GDSC1 1.491 6.2626 0.5489 39.5058
RCM-1 [Human ESC] GDSC1; CTRP2 1.5223 6.2484 0.8156 25.9429
SW48 GDSC1 1.6505 5.3936 1.0569 36.5112
SNU-1033 CTRP2 1.656 7.5096 0.4702 26.7351
LS411N GDSC1 1.7188 5.9319 0.9228 36.6315
NCI-H716 GDSC1; CTRP2 1.8911 6.3706 1.1677 23.5896
SW626 GDSC1 1.9837 7.4265 0.5578 36.4053
SW1417 GDSC1; CTRP2 2.2059 8.389 0.6645 24.4932
SNU-503 CTRP2 2.3151 9.9878 0.0457 26.269
LS1034 GDSC1; CTRP2 2.4587 8.9876 0.6504 23.8522
SW620 GDSC1; CTRP2 2.5349 7.2636 1.4924 20.5647
COLO 678 GDSC1; CTRP2 2.7126 8.8665 0.9597 22.0722
SW1463 GDSC1 2.7292 8.7332 0.6803 31.9341
KM12 GDSC1; CTRP2 2.8769 7.175 1.885 18.1404
SW1116 GDSC1 3.114 12.6732 -0.8986 35.4053
CW-2 GDSC1; CTRP2 3.187 8.6655 1.5225 18.7429
NCI-H508 CTRP2 3.235 9.3879 1.2274 19.7494
LS123 GDSC1 3.6274 6.3871 2.6657 15.7687
CL-11 GDSC1; CTRP2 3.6379 13.0593 -0.1881 23.6958
HCT 8 CTRP2 3.7284 8.3455 2.2004 14.7421
HCC2998 GDSC1 3.77 10.0612 0.9803 25.8629
SNU-61 GDSC1; CTRP2 3.9002 11.3864 0.8757 19.4791
HCC-56 CTRP2 4.1944 9.4429 2.102 14.0701
SNU-C4 CTRP2 4.9123 9.6322 2.6395 10.3524
RKO GDSC1; CTRP2 6.1949 13.7344 1.617 12.1279
COLO201 CTRP2 6.6843 16.9824 0.3809 15.7737
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 -1.3257 3.1656 -1.5687 65.1357
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC1 -4.3333 -1.1913 -4.34 91.2822
HLE GDSC1 -2.6639 2.658 -2.9206 73.6637
Huh-7 GDSC1 -1.9501 2.3898 -2.1086 70.8065
SNU-398 GDSC1; CTRP2 -1.6463 3.4018 -1.8834 44.9807
JHH-7 GDSC1 -0.7681 3.0201 -0.9393 61.0653
JHH-2 GDSC1; CTRP2 -0.0534 3.2106 -0.1465 34.2649
SNU-475 GDSC1; CTRP2 0.1746 4.1904 -0.0637 33.2155
SNU-423 GDSC1; CTRP2 0.1985 4.3598 -0.0741 33.1659
JHH-5 CTRP2 0.2748 3.2865 0.1928 32.0479
PLC/PRF/5 CTRP2 0.5949 4.9958 0.2018 30.9486
SNU-449 GDSC1; CTRP2 0.6256 3.9552 0.4698 29.9619
SNU-387 GDSC1; CTRP2 0.7061 5.9375 0.039 31.1014
JHH-1 GDSC1; CTRP2 1.0475 4.5793 0.8002 27.472
JHH-4 GDSC1; CTRP2 1.2098 4.7057 0.9469 26.449
Hep-G2/C3A GDSC1 1.7899 7.7026 0.2374 38.5906
HLF CTRP2 1.86 6.452 1.1041 23.9108
HuH-1 GDSC1 1.8984 5.9398 1.1096 34.6659
SK-HEP-1 GDSC1; CTRP2 2.1831 10.1159 -0.1444 27.2268
HuH-6 CTRP2 2.8743 6.9767 1.9672 17.8298
Hep-G2 CTRP2 4.2107 8.4843 2.5883 12.0452
JHH-6 GDSC1; CTRP2 10.0549 20.4772 0.9961 8.9699
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 198 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1048 GDSC1 -3.6007 -0.9033 -3.6046 88.8964
NCI-H1666 GDSC1; CTRP2 -3.421 7.6078 -5.0023 54.0469
NCI-H1876 GDSC1 -2.6312 -0.3808 -2.6335 82.9936
NCI-H1304 GDSC1 -2.619 0.7776 -2.6533 79.09
NCI-H1341 GDSC1; CTRP2 -2.1851 1.7094 -2.2441 48.2166
NCI-H1648 GDSC1 -1.5376 0.4876 -1.5408 72.1866
NCI-H847 GDSC1 -1.5199 1.8352 -1.585 69.2775
NCI-H69 GDSC1 -1.4472 3.4833 -1.7665 65.3496
Calu-3 GDSC1 -1.2981 4.2324 -1.7872 63.1291
NCI-H1184 CTRP2 -1.2784 3.8742 -1.5752 42.7632
NCI-H2795 GDSC1 -1.2492 1.3344 -1.2696 68.0137
HCC78 GDSC1 -1.1589 1.9509 -1.2166 66.1173
ABC-1 GDSC1 -1.1537 3.4927 -1.4495 63.3608
IST-SL2 GDSC1 -1.0809 2.5035 -1.1957 64.4884
NCI-H1793 GDSC1; CTRP2 -1.0618 6.0645 -1.9236 42.3962
NCI-H1623 GDSC1; CTRP2 -1.0461 3.6396 -1.2783 41.1552
SBC-3 GDSC1 -1.0006 1.1299 -1.0086 65.8386
COR-L311 GDSC1 -0.921 1.167 -0.9286 64.949
EMC-BAC-2 GDSC1 -0.9067 0.9685 -0.9104 64.9741
NCI-H187 GDSC1 -0.8988 3.3832 -1.1495 61.6314
NCI-H322M GDSC1 -0.8882 2.5453 -0.9959 62.7822
EPLC-272H GDSC1; CTRP2 -0.8847 2.7909 -0.9786 39.7688
COR-L303 GDSC1 -0.8563 1.4678 -0.872 63.939
Lu-135 GDSC1 -0.7734 1.8484 -0.8063 62.6457
NCI-H720 GDSC1 -0.7612 1.1468 -0.7662 63.1993
NCI-H596 GDSC1 -0.7559 2.4302 -0.8408 61.7434
NCI-H292 GDSC1 -0.6687 2.3996 -0.7449 60.9515
NCI-H64 GDSC1 -0.6596 1.3025 -0.6663 61.9377
Ms-1 GDSC1 -0.6435 2.1234 -0.6914 61.0159
SBC-1 GDSC1 -0.6177 2.7488 -0.735 60.0555
HCC4006 CTRP2 -0.5932 2.8742 -0.6795 37.8223
SW1271 GDSC1 -0.5275 3.9264 -0.8679 57.9763
NCI-H2347 GDSC1 -0.5148 3.7942 -0.8224 58.0021
NCI-H1688 GDSC1 -0.4917 3.2114 -0.6752 58.3861
NCI-H2171 GDSC1; CTRP2 -0.4709 1.5407 -0.4753 36.758
NCI-H2818 GDSC1 -0.47 2.4584 -0.5412 58.913
NCI-H2444 GDSC1 -0.4329 2.8743 -0.5556 58.1571
NCI-H1770 GDSC1 -0.4013 1.4869 -0.4083 58.8497
DV-90 CTRP2 -0.3818 3.1693 -0.4906 36.4899
NCI-H2810 GDSC1 -0.3506 2.6833 -0.4412 57.4974
CPC-N GDSC1 -0.3414 2.5951 -0.4206 57.4722
NCI-H446 GDSC1 -0.3199 1.5816 -0.3279 57.8518
SBC-5 GDSC1 -0.2275 1.6592 -0.236 56.7301
UMC-11 GDSC1 -0.1812 2.4828 -0.2389 55.8295
NCI-H2196 GDSC1; CTRP2 -0.1649 4.7202 -0.5555 35.884
NCI-H727 GDSC1 -0.1638 3.0537 -0.2947 55.3184
NCI-H209 GDSC1 -0.1136 2.3502 -0.1557 55.1379
NCI-H1581 GDSC1 -0.1092 2.604 -0.1756 54.9749
NCI-H810 GDSC1; CTRP2 -0.0946 4.2892 -0.3772 35.1173
NCI-H1693 CTRP2 -0.0747 5.2679 -0.6048 35.6912
NCI-H146 GDSC1; CTRP2 -0.0673 3.6219 -0.2201 34.5448
NCI-H1781 GDSC1 -0.0441 3.4053 -0.2275 53.9061
NCI-H650 GDSC1 -0.0353 4.2954 -0.4261 53.4245
LB647-SCLC GDSC1 -0.035 3.127 -0.168 53.9355
NCI-H290 GDSC1 -0.0184 4.1707 -0.3743 53.3205
HOP-92 CTRP2 0.0179 4.9505 -0.4158 34.8276
CAL-12T GDSC1 0.0546 3.6695 -0.1746 52.7999
LCLC-97TM1 GDSC1; CTRP2 0.0618 4.7219 -0.3087 34.3582
A-427 GDSC1 0.077 2.3468 0.0436 52.9357
COR-L105 GDSC1; CTRP2 0.079 4.2904 -0.1888 33.9362
NCI-H661 GDSC1; CTRP2 0.0814 7.45 -1.177 36.557
IST-SL1 GDSC1 0.0927 3.1448 -0.0336 52.5594
NCI-H1568 GDSC1; CTRP2 0.1025 3.9572 -0.0956 33.5646
HCC33 GDSC1 0.1132 3.0572 0.002 52.3577
NCI-H1155 GDSC1 0.1487 3.8214 -0.1061 51.8019
LC-2/ad GDSC1 0.1574 2.4334 0.1208 51.972
NCI-H1975 GDSC1 0.2179 3.0629 0.1134 51.1869
DMS 53 GDSC1; CTRP2 0.2235 4.3409 -0.0427 32.9815
NCI-H1734 GDSC1 0.2245 5.432 -0.4955 50.8373
HOP-62 GDSC1; CTRP2 0.2554 4.5595 -0.0579 32.9198
NCI-H2087 GDSC1; CTRP2 0.2611 4.5976 -0.0609 32.9095
NCI-H1435 GDSC1; CTRP2 0.2815 9.3283 -1.7276 37.0447
Lu-139 GDSC1 0.2841 3.3038 0.1457 50.4241
LK-2 GDSC1 0.2992 2.6031 0.2549 50.2721
NCI-H2135 GDSC1 0.3112 3.7808 0.0799 50.1145
BEN GDSC1 0.3265 5.206 -0.3082 49.9587
PaCa-3 GDSC1 0.3348 3.4634 0.1714 49.8571
NCI-H510A GDSC1 0.3353 2.4817 0.3028 49.8387
NCI-H2066 GDSC1 0.3912 3.1681 0.2832 49.2047
NCI-H841 GDSC1; CTRP2 0.3962 4.449 0.121 31.8732
NCI-H82 GDSC1 0.4087 2.6687 0.3638 48.9594
COR-L321 GDSC1 0.4331 3.2005 0.3231 48.7224
RERF-LC-MS GDSC1; CTRP2 0.4873 3.8803 0.3337 30.8726
EKVX GDSC1; CTRP2 0.4896 5.339 -0.0099 31.9741
COLO 668 GDSC1; CTRP2 0.5334 4.218 0.32 30.765
NCI-H524 GDSC1; CTRP2 0.5373 3.7547 0.4083 30.4588
NCI-H2085 CTRP2 0.5914 6.6856 -0.345 32.6415
Lu-65 GDSC1; CTRP2 0.6005 4.1158 0.4129 30.2347
NCI-H1436 GDSC1 0.628 6.0935 -0.3014 47.4526
NCI-H1105 GDSC1; CTRP2 0.6318 5.1455 0.2008 30.8295
NCI-H835 GDSC1 0.6336 4.0948 0.3565 46.6768
NCI-H226 GDSC1 0.6561 3.5942 0.4939 46.226
NCI-H211 GDSC1 0.7015 5.3417 0.0519 46.5007
NCI-H1563 GDSC1; CTRP2 0.7136 4.6483 0.42 29.8399
NCI-H1836 GDSC1 0.7188 8.7336 -1.3117 47.5254
NCI-H1694 GDSC1; CTRP2 0.7918 3.5993 0.7033 28.6295
NCI-H647 GDSC1; CTRP2 0.8098 3.9694 0.666 28.6972
NCI-H3255 GDSC1 0.8268 3.084 0.7606 43.9505
NCI-H520 GDSC1; CTRP2 0.8543 4.1828 0.6748 28.5226
HCC827 GDSC1 0.8742 4.4695 0.5181 44.2146
NCI-H2803 GDSC1 0.8889 3.7665 0.7111 43.5683
NCI-H2869 GDSC1 0.8898 5.4069 0.2326 44.691
NCI-H2009 GDSC1 0.9032 4.9474 0.4032 44.2361
NCI-H1755 GDSC1; CTRP2 0.91 4.1759 0.7364 28.1328
NCI-H2722 GDSC1 0.9297 6.1184 0.0111 44.7772
HCC2935 CTRP2 0.9441 4.082 0.7908 27.8365
NCI-H1355 GDSC1; CTRP2 1.0316 6.0075 0.3688 28.9857
NCI-H1944 GDSC1; CTRP2 1.0331 4.001 0.9011 27.1717
DMS 114 GDSC1; CTRP2 1.0461 5.664 0.4972 28.5106
NCI-H1703 GDSC1; CTRP2 1.0599 6.1371 0.3552 28.9412
LUDLU-1 CTRP2 1.0643 4.2788 0.8833 27.1324
NCI-H2731 GDSC1 1.0723 4.2705 0.7895 41.7908
NCI-H1869 GDSC1; CTRP2 1.0728 7.4466 -0.1201 30.4131
LCLC-103H GDSC1 1.1059 5.0384 0.5934 42.1385
NCI-H1573 GDSC1; CTRP2 1.1219 4.77 0.8353 27.1142
NCI-H1650 GDSC1 1.1566 3.7254 1.0102 40.2778
Sq-1 CTRP2 1.202 5.7807 0.6291 27.5727
NCI-H358 GDSC1 1.239 5.0181 0.7445 40.6504
NCI-H2405 GDSC1 1.2437 6.444 0.2145 42.1199
SK-MES-1 GDSC1; CTRP2 1.2458 3.8096 1.1591 25.6006
NCI-H2029 GDSC1; CTRP2 1.2504 8.3733 -0.3145 30.4436
LOU-NH91 GDSC1; CTRP2 1.2678 5.5934 0.7609 26.9136
LXF 289 GDSC1; CTRP2 1.2904 4.6992 1.0364 25.8827
NCI-H2373 GDSC1 1.3067 18.9292 -5.625 46.996
NCI-H1385 CTRP2 1.3111 4.7869 1.0375 25.814
NCI-H2141 GDSC1; CTRP2 1.4355 8.0715 0.0057 28.9079
NCI-H2591 GDSC1 1.4557 5.1933 0.9191 38.4295
NCI-H322 CTRP2 1.4623 4.1493 1.3382 24.2876
NCI-H2081 GDSC1; CTRP2 1.4789 5.2072 1.1076 25.0447
DMS 454 CTRP2 1.4845 4.874 1.2046 24.6851
LK2 CTRP2 1.4869 3.2296 1.4692 23.7598
NCI-H2286 CTRP2 1.5093 9.5353 -0.5553 30.3582
PC-14 GDSC1 1.5698 4.021 1.3949 35.4117
ChaGo-K-1 GDSC1; CTRP2 1.5796 4.8201 1.322 23.9745
NCI-H2291 GDSC1 1.5968 26.5319 -9.1286 47.2231
T3M-10 CTRP2 1.6058 9.8541 -0.6012 30.2044
NCI-H23 GDSC1; CTRP2 1.6254 5.2181 1.2643 24.0376
NCI-H2170 GDSC1; CTRP2 1.6353 3.5723 1.5992 22.8332
DMS 273 GDSC1; CTRP2 1.6928 5.8049 1.154 24.2276
NCI-H522 GDSC1; CTRP2 1.7355 5.2838 1.3652 23.3409
HARA [Human squamous cell lung carcinoma] GDSC1 1.8436 7.1193 0.552 37.2559
NCI-H2595 GDSC1 1.8794 6.1188 1.0165 35.2062
EBC-1 GDSC1; CTRP2 1.9055 6.1457 1.2655 23.1922
SW1573 GDSC1; CTRP2 1.9158 10.3632 -0.5242 29.1002
NCI-H2110 GDSC1; CTRP2 1.9519 5.944 1.387 22.6128
NCI-H196 GDSC1 1.964 4.1557 1.7921 30.5513
NCI-H3122 GDSC1 1.9763 5.7539 1.2665 33.4245
NCI-H2030 GDSC1 1.9848 5.5932 1.3389 33.0029
HCC1438 CTRP2 2.0199 7.257 0.9565 23.9802
NCI-H1092 GDSC1; CTRP2 2.0394 8.0314 0.6499 25.0104
NCI-H1915 GDSC1; CTRP2 2.0407 4.631 1.8693 20.6023
HCC44 GDSC1 2.0497 4.5659 1.7716 30.1504
NCI-H2369 GDSC1 2.08 6.0854 1.2408 32.9195
IA-LM GDSC1; CTRP2 2.1109 6.1799 1.4743 21.8272
NCI-H2804 GDSC1 2.1355 6.2095 1.2467 32.5584
EMC-BAC-1 GDSC1 2.1566 9.253 -0.1189 37.6051
NCI-H1395 CTRP2 2.1694 6.8135 1.2938 22.325
Lu-134-A GDSC1 2.2363 7.1825 0.9232 33.4936
A-549 GDSC1; CTRP2 2.2399 5.8587 1.7282 20.5135
NCI-H2228 GDSC1 2.2698 6.7482 1.1517 32.2458
COR-L23 GDSC1 2.2788 7.2163 0.9509 33.1313
RERF-LC-Ad2 CTRP2 2.312 7.9539 0.9646 23.1312
NCI-H2023 GDSC1; CTRP2 2.3138 7.4392 1.188 22.3097
Lu-165 GDSC1 2.3207 7.1332 1.0307 32.5329
NCI-H1339 CTRP2 2.363 7.178 1.3491 21.5758
NCI-H1651 GDSC1; CTRP2 2.4833 6.3339 1.8155 19.4881
SHP-77 GDSC1 2.5137 5.046 2.1124 25.2612
COR-L88 GDSC1; CTRP2 2.6251 5.4287 2.29 17.3064
SK-LU-1 GDSC1; CTRP2 2.6468 8.066 1.2574 21.1462
NCI-H460 GDSC1; CTRP2 2.6949 6.9365 1.7971 18.9697
NCI-H441 GDSC1; CTRP2 2.695 10.5062 0.173 24.8496
NCI-H2122 GDSC1; CTRP2 2.7705 6.44 2.0794 17.6821
NCI-H345 GDSC1 2.7972 11.6884 -0.6982 36.1825
Calu-1 CTRP2 2.8132 9.3376 0.8402 22.2435
COR-L95 GDSC1; CTRP2 2.8139 6.8189 1.9706 17.9798
NCI-H526 GDSC1 2.8654 3.3725 2.8645 18.2122
Lu-99A GDSC1 2.875 6.3729 1.934 24.503
NCI-H2342 GDSC1; CTRP2 2.9894 10.4114 0.5018 22.9887
RERF-LC-Sq1 GDSC1 2.9955 8.0179 1.2784 27.7801
NCI-H1838 GDSC1 3.0154 9.693 0.4826 31.3861
NCI-H2461 GDSC1 3.2426 9.4992 0.7866 29.0514
KNS-62 GDSC1; CTRP2 3.264 8.1803 1.8248 17.373
Calu-6 GDSC1; CTRP2 3.3162 7.6526 2.1201 16.0768
VMRC-LCD CTRP2 3.3256 10.6498 0.7061 21.4405
NCI-H1437 GDSC1 3.4994 7.2954 2.1043 20.3791
NCI-H2126 CTRP2 3.5812 9.6173 1.4477 18.0698
NCI-H513 GDSC1 3.6872 9.3588 1.2568 24.7666
NCI-H1993 GDSC1 4.1564 14.1968 -0.7541 31.1796
NCI-H1299 GDSC1 4.2508 9.1685 1.8391 19.0418
LC-1/sq-SF CTRP2 4.2672 13.9939 -0.0935 21.9838
NCI-H1373 CTRP2 4.5851 11.7158 1.3186 16.3275
HCC15 GDSC1 4.6718 10.0868 1.7257 18.2202
NCI-H838 GDSC1; CTRP2 4.9089 7.3661 3.7687 5.6295
RERF-LC-KJ GDSC1 4.9103 13.6795 0.1239 25.5512
NCI-H889 CTRP2 4.9893 13.049 0.9961 16.7122
NCI-H1792 GDSC1; CTRP2 5.3569 12.84 1.4039 14.459
NCI-H2172 GDSC1; CTRP2 9.3747 19.2065 1.1645 9.2073
Hs 888.Lu CTRP2 1.1654 5.4724 0.6869 27.4887
⏷ Show the Full List of 198 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 -1.4646 2.7497 -1.6438 66.9056
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 0.5217 6.1319 -0.226 32.5255
Aska-SS CTRP2 1.5885 6.4249 0.8227 25.7186
Rh41 GDSC1 -5.9153 -3.4299 -5.9156 98.1691
SW982 GDSC1 -4.9148 -1.6376 -4.9209 93.2862
EW-8 GDSC1 -4.7151 -2.899 -4.7151 97.4079
Hs 633.T GDSC1 -4.4053 -2.1369 -4.4058 94.8184
VA-ES-BJ GDSC1 -2.7276 6.9657 -4.2265 65.6766
SW872 GDSC1 -1.8857 4.0465 -2.3794 66.8057
SW684 GDSC1 -1.8617 20.3433 -9.2856 55.3125
A-204 GDSC1; CTRP2 -1.6046 4.3661 -2.0385 44.9834
Rh30 GDSC1 -1.1624 2.0237 -1.227 66.0172
GCT GDSC1; CTRP2 -0.4678 3.4635 -0.625 37.1994
Rh18 GDSC1; CTRP2 -0.2327 5.0333 -0.7116 36.5587
KYM-1 GDSC1; CTRP2 -0.0514 3.0785 -0.1289 34.2016
SK-LMS-1 GDSC1; CTRP2 -0.0173 4.6085 -0.3669 34.8108
G-401 GDSC1; CTRP2 0.0525 3.4593 -0.0667 33.6452
G-402 GDSC1; CTRP2 0.1057 4.4466 -0.1947 33.8607
TE 441.T CTRP2 0.4583 4.1333 0.2555 31.2274
HT-1080 GDSC1; CTRP2 1.0879 4.1118 0.9407 26.8593
MFH-ino GDSC1 1.3536 7.059 0.0728 41.719
Hs 729.T CTRP2 1.4341 5.1273 1.0815 25.2757
TE 617.T CTRP2 1.6237 3.9056 1.5493 23.0415
RKN GDSC1; CTRP2 1.7123 4.1383 1.6093 22.55
RD GDSC1; CTRP2 1.7164 6.1576 1.0574 24.5035
MES-SA GDSC1 1.7949 6.2055 0.8921 36.2689
TTC-709 CTRP2 1.8051 6.0524 1.1905 23.7608
Tm87-16 CTRP2 2.3869 6.378 1.6958 20.211
SK-UT-1 GDSC1; CTRP2 2.7527 9.1155 0.8842 22.2414
BT-16 CTRP2 4.3477 9.8413 2.0432 13.9733
BT-12 CTRP2 5.7287 7.1803 4.4785 1.3369
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.3879 8.7877 0.6703 23.9737
JHOS-4 GDSC1 -1.9032 1.6158 -1.9676 72.5092
A2780 GDSC1; CTRP2 -1.2096 3.832 -1.4921 42.3019
DOV13 GDSC1 -1.1244 1.5046 -1.1494 66.5635
RMG-I GDSC1; CTRP2 -0.9213 10.4168 -3.4407 43.6566
SNU-840 CTRP2 -0.3031 9.6527 -2.4734 40.3314
TOV-112D GDSC1; CTRP2 0.1078 3.4247 -0.0028 33.2509
OVCAR-3 GDSC1 0.3485 7.2499 -1.0572 49.8129
JHOM-1 CTRP2 0.3512 5.3541 -0.1652 32.9218
FU-OV-1 GDSC1; CTRP2 0.4472 6.5193 -0.4407 33.401
OVISE GDSC1 0.568 7.622 -0.9831 48.299
Kuramochi GDSC1 0.5899 4.9861 0.05 47.4515
IGROV-1 GDSC1; CTRP2 0.6194 7.0211 -0.4389 32.8172
OVK18 GDSC1; CTRP2 0.7169 3.8442 0.5869 29.2681
Caov-3 GDSC1; CTRP2 0.7535 6.258 -0.0182 31.1246
TYK-nu GDSC1; CTRP2 0.7923 4.4392 0.5541 29.1332
SK-OV-3 GDSC1; CTRP2 0.838 5.211 0.4072 29.478
OVCAR-5 GDSC1; CTRP2 0.9051 7.7969 -0.4378 31.8822
OAW28 GDSC1; CTRP2 0.9234 5.7125 0.3483 29.3985
COV644 CTRP2 0.9846 4.7847 0.6819 28.0789
JHOS-2 GDSC1; CTRP2 1.1094 4.6253 0.8568 27.0796
OAW42 GDSC1; CTRP2 1.1947 5.8358 0.6031 27.6839
Caov-4 GDSC1 1.1989 8.8436 -0.8752 44.3338
OV7 CTRP2 1.2107 7.0902 0.1664 29.0849
MCAS CTRP2 1.3275 5.1793 0.9504 26.0674
OV-90 GDSC1; CTRP2 1.3313 4.4223 1.1435 25.3808
ES-2 GDSC1 1.4142 4.0543 1.2175 37.4109
HEY A8 CTRP2 1.4215 7.8425 0.0867 28.6946
OVCAR-4 GDSC1 1.5063 6.5146 0.4615 39.6776
COV362 CTRP2 1.5935 6.4193 0.8302 25.677
COV434 CTRP2 1.6422 6.0988 0.9982 24.9364
OV56 GDSC1; CTRP2 2.3529 4.2227 2.2837 18.1664
TOV-21G GDSC1; CTRP2 2.4407 5.2875 2.133 18.4315
OVTOKO GDSC1 2.5305 6.6003 1.483 29.0562
OC 314 GDSC1; CTRP2 2.8778 9.2103 0.9634 21.6299
EFO-27 GDSC1; CTRP2 2.8802 6.6027 2.1295 17.1879
EFO-21 GDSC1; CTRP2 3.1664 10.2653 0.7411 21.7055
OVCAR-8 GDSC1; CTRP2 6.4253 14.8873 1.2211 13.2333
OVKATE GDSC1 9.4602 21.1754 -0.3046 16.0952
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 2.4854 6.8538 1.6113 20.2522
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 3.603 7.6469 2.4083 14.2095
P-STS CTRP2 4.2368 8.46 2.6243 11.8388
SYO-1 CTRP2 6.8697 13.841 2.0588 9.3292
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1 0.2254 2.6924 0.1685 51.1396
MSTO-211H GDSC1; CTRP2 0.4354 6.4453 -0.4275 33.4038
NCI-H2452 GDSC1 1.8795 5.4145 1.2948 33.8895
NCI-H28 GDSC1 1.9927 5.8389 1.2499 33.4056
MPP 89 GDSC1; CTRP2 2.2613 6.4621 1.5293 21.1905
NCI-H2052 GDSC1; CTRP2 2.5836 6.5703 1.8295 19.1534
JL-1 CTRP2 5.4837 12.2684 1.7916 12.7102
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 GDSC1 -1.5904 1.7145 -1.6483 70.0802
PC-3 GDSC1 -0.5428 3.8839 -0.8742 58.1454
VCaP GDSC1; CTRP2 0.8051 4.6826 0.5115 29.2351
LNCaP clone FGC GDSC1; CTRP2 1.2869 3.9597 1.1808 25.3933
PaCa-3 CTRP2 1.8309 7.7726 0.544 25.9727
DU145 GDSC1; CTRP2 1.9895 7.5475 0.8041 24.6106
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; CTRP2 5.5289 10.4519 2.733 8.8052
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -0.061 2.9572 -0.1697 54.2878
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AGS GDSC1 -6.739 -0.4592 -6.8558 90.2105
23132/87 GDSC1 -5.7241 15.9275 -11.0771 64.6916
GCIY GDSC1 -5.5431 0.5242 -5.694 86.7554
SCH GDSC1 -4.8394 16.5698 -10.4636 62.7744
MKN1 GDSC1 -3.8645 2.0902 -4.1167 79.2769
HSC-39 GDSC1 -3.6556 -1.5759 -3.656 91.6604
ECC10 GDSC1 -2.7042 0.9714 -2.7536 78.8569
OCUM-1 GDSC1 -2.031 10.8606 -5.0655 59.5409
HGC-27 GDSC1; CTRP2 -1.8305 1.2706 -1.852 45.8438
TGBC11TKB GDSC1 -1.612 3.9855 -2.0652 65.4237
RERF-GC-1B GDSC1 -1.5446 3.2621 -1.8253 66.3922
NCC-StC-K140 CTRP2 -1.4055 2.1564 -1.465 43.1153
SNU-1 GDSC1; CTRP2 -1.3143 2.7729 -1.4324 42.6442
RF-48 GDSC1 -0.765 5.1248 -1.4679 58.5279
Hs 746.T GDSC1; CTRP2 -0.3425 4.3372 -0.6576 36.8229
SNU-216 CTRP2 -0.2819 3.1761 -0.3852 35.8121
Fu97 GDSC1; CTRP2 0.2609 3.9987 0.0678 32.5021
IM95 GDSC1; CTRP2 0.2744 4.5307 -0.0305 32.7691
NUGC-4 GDSC1 0.8575 5.6779 0.1001 45.1789
MKN28 GDSC1 1.2006 9.5324 -1.1893 44.7086
SNU-601 CTRP2 1.2276 6.0416 0.5696 27.6957
SNU-16 GDSC1; CTRP2 1.3349 3.0394 1.322 24.7561
MKN7 GDSC1; CTRP2 1.651 6.2815 0.9423 25.1088
HuG1-N CTRP2 1.8161 12.5203 -1.6355 32.2312
KATO III GDSC1; CTRP2 2.1001 7.0163 1.1391 23.0901
LMSU CTRP2 2.1694 10.0041 -0.1062 27.146
NUGC-3 GDSC1; CTRP2 2.4518 10.8089 -0.2065 26.6938
MKN74 CTRP2 2.4975 10.0766 0.1836 25.333
SH-10-TC CTRP2 2.7173 7.9567 1.3778 20.5065
MKN45 GDSC1 2.9961 13.0562 -1.1939 36.5775
KE-39 CTRP2 3.2791 10.8332 0.5733 22.0224
SNU-5 GDSC1 6.2299 10.9989 2.4081 9.1403
NCI-N87 GDSC1 6.7276 22.3796 -2.7888 29.366
SNU-685 CTRP2 2.284 6.6896 1.4645 21.3673
SNG-M GDSC1; CTRP2 4.2816 11.5553 1.1333 17.6776
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8505C GDSC1 -5.5474 1.7281 -5.8676 83.4157
IHH-4 GDSC1 -4.7789 1.9099 -5.0707 81.7532
CAL-62 GDSC1 -4.6491 4.0438 -5.3938 76.2921
KMH-2 GDSC1 -4.6456 0.2851 -4.7267 86.4679
B-CPAP GDSC1 -4.503 0.3738 -4.5847 85.9642
K5 GDSC1 -4.3834 2.4707 -4.7446 79.4546
HTC-C3 GDSC1 -4.0021 4.2892 -4.7534 74.2156
8305C GDSC1 -3.1147 2.2488 -3.3364 76.5429
BHT-101 GDSC1 -0.5554 1.8322 -0.5795 60.3718
ML-1 [Human leukemia] GDSC1 0.2751 3.584 0.0829 50.5081
SW579 CTRP2 0.2876 3.7654 0.1381 32.1839
ASH-3 GDSC1 0.3119 2.7897 0.2493 50.1178
CGTH-W-1 GDSC1 0.4865 4.3394 0.1314 48.3247
WRO GDSC1 0.6728 9.6459 -1.7691 48.0097
TT2609-C02 GDSC1; CTRP2 1.5392 6.1771 0.8593 25.7384
TT GDSC1 1.9073 6.1692 1.025 34.9939
FTC-133 GDSC1; CTRP2 2.043 12.6914 -1.4984 31.2994
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SAT [Human HNSCC] GDSC1 -7.7802 5.4021 -9.1955 78.7231
SKN-3 GDSC1 -6.5815 12.0536 -10.3147 68.9962
SCC-15 GDSC1 -5.7391 0.9394 -5.9534 85.7655
Detroit 562 GDSC1 -4.9282 2.5264 -5.3455 80.3904
BHY GDSC1 -4.9132 -0.0373 -4.9813 87.8607
BB30-HNC GDSC1 -4.823 -0.7445 -4.8497 90.1541
OSC-20 GDSC1 -4.5936 3.7111 -5.2481 76.8958
NCI-H3118 GDSC1 -4.4846 2.3627 -4.8336 79.9569
Ca9-22 GDSC1 -4.4091 -0.684 -4.4286 89.5134
PCI-15A GDSC1 -4.382 1.7155 -4.6132 81.5519
BICR 10 GDSC1 -3.232 4.9027 -4.0875 70.7059
OSC-19 GDSC1 -2.9531 5.815 -4.0703 68.1572
CAL-27 GDSC1 -2.5507 1.9361 -2.6872 75.1678
SCC-25 GDSC1; CTRP2 -2.5052 4.674 -3.0966 50.2422
DOK GDSC1 -2.0102 0.4364 -2.0177 76.3899
HO-1-N-1 GDSC1 -1.8853 1.709 -1.9573 72.1489
HSC-2 GDSC1; CTRP2 -1.4355 0.4708 -1.4365 43.1728
CAL-33 GDSC1; CTRP2 -1.4333 1.3511 -1.4485 43.1959
LB771-HNC GDSC1 -1.4003 3.2765 -1.6717 65.4324
PCI-04B GDSC1 -1.2333 1.6514 -1.2709 67.3077
JHU-011 GDSC1 -1.0533 1.6967 -1.087 65.5902
HSC-3 GDSC1 -0.9408 3.4483 -1.2086 61.8618
BICR 56 CTRP2 -0.524 4.5292 -0.9 38.1508
PE/CA-PJ15 GDSC1; CTRP2 -0.4702 3.9069 -0.7057 37.4343
PCI-06A GDSC1 -0.344 3.3951 -0.5504 56.8478
HSC-4 GDSC1; CTRP2 -0.3409 6.4809 -1.2794 38.3278
BICR 78 GDSC1 -0.0965 3.106 -0.2307 54.5912
SCC-4 GDSC1; CTRP2 0.0093 3.637 -0.1402 34.0276
SCC-9 GDSC1; CTRP2 0.1608 5.0953 -0.2992 33.9822
PE/CA-PJ49 CTRP2 0.2245 3.5547 0.1035 32.5098
BICR 31 GDSC1; CTRP2 0.2248 5.9423 -0.4853 34.2932
PE/CA-PJ41 (clone D2) CTRP2 0.4034 5.2598 -0.0809 32.4859
PE/CA-PJ34 (clone C12) CTRP2 0.4797 3.8159 0.3364 30.8887
JHU-022 GDSC1 0.6673 84.5295 -38.8667 49.774
BICR 6 CTRP2 0.872 6.9557 -0.1437 31.1246
KOSC-2 GDSC1 0.9145 4.9734 0.407 44.1358
FaDu GDSC1; CTRP2 1.6489 5.6591 1.1544 24.3588
BICR 16 CTRP2 2.286 8.1517 0.8511 23.6114
BICR 18 CTRP2 2.3527 8.593 0.7227 23.8853
HO-1-u-1 GDSC1 2.9792 6.3099 2.0674 23.094
PCI-30 GDSC1 4.6563 16.6024 -1.542 31.7641
BICR 22 GDSC1; CTRP2 4.9232 8.8524 3.0385 8.6654
PCI-38 GDSC1 6.6308 8.3869 3.746 0.5409
KON GDSC1 6.6356 8.585 3.6749 0.7884
SAS GDSC1 6.9121 8.9665 3.645 0.7101
BB49-HNC GDSC1 7.27 9.9433 3.4258 1.2899
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 GDSC1 -1.9291 1.384 -1.9761 73.2942
CAL-29 GDSC1 -1.882 0.7867 -1.8966 74.5232
BFTC-905 GDSC1 -0.9121 1.323 -0.9238 64.6868
RT-112 GDSC1; CTRP2 -0.9063 1.1605 -0.9096 39.655
UM-UC-3 GDSC1; CTRP2 -0.7736 2.2489 -0.813 38.881
SW780 GDSC1 -0.7437 2.544 -0.8417 61.4807
SW1710 GDSC1; CTRP2 -0.6783 1.8603 -0.6945 38.1774
U-BLC1 CTRP2 -0.6539 2.8182 -0.7375 38.2161
647V GDSC1 0.0249 2.8453 -0.0623 53.395
TCCSUP GDSC1 0.0616 2.6738 -0.0027 53.0351
639V GDSC1 0.5091 4.9422 -0.0237 48.2275
KMBC-2 CTRP2 1.1641 5.5383 0.6652 27.5672
T24 GDSC1; CTRP2 1.4925 6.0222 0.863 25.867
BC-3C CTRP2 1.6356 3.4706 1.6078 22.8032
HT-1197 GDSC1; CTRP2 1.8487 8.7262 0.1502 27.233
J82 GDSC1; CTRP2 1.869 5.6111 1.4091 22.7792
KU-19-19 GDSC1 2.104 5.7798 1.3912 32.0003
HT-1376 GDSC1; CTRP2 2.2094 5.6795 1.7564 20.4991
UM-UC-1 CTRP2 2.274 6.0819 1.6855 20.5726
RT-4 GDSC1; CTRP2 3.3237 7.7844 2.0672 16.2673
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ME-180 GDSC1 -6.404 0.2248 -6.5717 88.2359
OMC-1 [Human cervical carcinoma] GDSC1 -5.4441 1.7757 -5.7644 83.1529
Ca Ski GDSC1 -5.3373 0.5476 -5.4789 86.4798
SKN GDSC1 -3.3659 4.1241 -4.0148 72.7174
C-33 A GDSC1 -2.2339 2.1302 -2.3752 73.0579
TC-YIK GDSC1 -2.2155 1.2892 -2.2676 75.3414
HT-3 GDSC1 -1.9548 3.4886 -2.3198 68.2936
SiHa GDSC1 -1.8073 15.5818 -6.9777 56.5493
PA-1 GDSC1 -1.7953 0.1927 -1.7974 75.1481
BPH-1 GDSC1 -1.7646 0.2474 -1.767 74.761
HEC-1 GDSC1 -1.6806 7.1874 -3.1857 61.2966
UWB1.289 GDSC1 -1.5822 2.9889 -1.8125 67.1866
JAR GDSC1 -1.4706 0.3664 -1.4723 71.6969
SW954 GDSC1 -1.4529 0.8604 -1.4616 70.739
C-4-I GDSC1 -1.3967 3.3141 -1.6756 65.3381
NEC8 GDSC1 -1.2153 1.0847 -1.2258 68.0928
NCC-IT GDSC1 -1.0246 1.7119 -1.0582 65.2955
NT2-D1 GDSC1 -0.944 0.7791 -0.9459 65.5402
OVMIU GDSC1 -0.8977 7.6489 -2.5332 57.1682
LB831-BLC GDSC1 -0.7983 3.4889 -1.0625 60.6893
KGN GDSC1 -0.7626 1.2899 -0.7707 63.1035
SW962 GDSC1 -0.2032 3.4731 -0.4133 55.4492
HEY GDSC1 -0.1968 2.5776 -0.2654 55.9473
SW756 GDSC1 -0.0864 8.9107 -2.2144 52.3103
MS751 GDSC1 -0.0234 3.2488 -0.1763 53.762
OVCA433 GDSC1 -0.0109 3.5148 -0.2133 53.5219
PWR-1E GDSC1 -0.0107 3.1219 -0.1411 53.6799
DoTc2 4510 GDSC1 0.0872 5.5944 -0.7004 51.9443
DSH1 GDSC1 0.2924 4.628 -0.1629 50.2832
ACC-OV7 GDSC1 0.5032 3.0366 0.4221 47.8715
JHOS-3 GDSC1 0.5363 4.4331 0.1597 47.8296
PEO1 GDSC1 0.6431 3.6804 0.4623 46.41
OVCA420 GDSC1 0.653 3.2409 0.5528 46.1335
CAL-39 GDSC1 0.765 3.2478 0.6719 44.7815
OV17R GDSC1 1.0704 5.6702 0.3317 43.089
SiSo GDSC1 1.243 11.0336 -1.8504 45.1674
JEG-3 GDSC1 1.4531 4.8642 1.0278 38.0008
HeLa GDSC1; CTRP2 2.1916 4.7506 2.0061 19.6479
SKG-IIIa GDSC1 8.42 19.928 -0.3869 18.4578
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028447)
2 Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov. 2009 Aug;8(8):627-44.