Details of the Drug

General Information of Drug (ID: DMI7PGZ)

Drug Name
ISIS 100743
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Antisense drug
Sequence
CTACACCAGTCATCTGGTAT
Cross-matching ID
TTD ID
D0JV0I

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ADAM10 messenger RNA (ADAM10 mRNA) TTVXEGU ADA10_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
ADAM10 messenger RNA (ADAM10 mRNA) DTT ADAM10 9.12E-20 0.59 0.82
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 US patent application no. 6,228,648, Antisense modulation of ADAM10 expression.