Details of the Drug

General Information of Drug (ID: DMIAUB1)

• Drug Name: Biphenyl-3-ylboronic acid
• Synonyms: 3-Biphenylboronic acid; 5122-95-2; Biphenyl-3-boronic acid; [1,1'-Biphenyl]-3-ylboronic acid; biphenyl-3-ylboronic acid; (3-phenylphenyl)boronic Acid; 3-biphenyl boronic acid; (3-phenylphenyl)boranediol; 3-PHENYLBENZENEBORONIC ACID; (1,1'-biphenyl-3-yl)boronic acid; [1,1'-Diphenyl]-3-ylboronic acid; MFCD01318102; Boronic acid, [1,1'-biphenyl]-3-yl-; AK-35405; Biphenyl-3-boronicacid; PubChem6404; Phenylboronic Acid, 5; Biphenyl-3-bronic acid; 3-biphenyl-boronic acid; ACMC-1AKSL; AC1MC0UE; Biphenyl-3-ylbronic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight; 198.03
  Logarithm of the Partition Coefficient; Not Available
  Rotatable Bond Count; 2
  Hydrogen Bond Donor Count; 2
  Hydrogen Bond Acceptor Count; 2
• Chemical Identifiers:
  Formula: C12H11BO2
  IUPAC Name: (3-phenylphenyl)boronic acid
  Canonical SMILES: B(C1=CC(=CC=C1)C2=CC=CC=C2)(O)O
  InChI: InChI=1S/C12H11BO2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14-15H
  InChIKey: GOXICVKOZJFRMB-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 2734315
  CAS Number: 5122-95-2
  TTD ID: D05GPK

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase. J Med Chem. 2008 Nov 27;51(22):7057-60.