Details of the Drug

General Information of Drug (ID: DMIEOAP)

Drug Name
COR-003
Synonyms
Panfungol; Orifungal M; Nizoral; Ketozole; Normocort; 65277-42-1; Ketoisdin; Nizoral a-D; Sebazole; Levoketoconazole; UNII-2DJ8R0NT7K; Ketoconazolum [INN-Latin]; Ketoconazol [INN-Spanish]; Ketoconazole, (2S,4R)-; (2S,4R)-ketoconazole; 142128-57-2; 2DJ8R0NT7K; Ketocanazole; Ketoconazolum; Brizoral; CHEMBL295698; CHEBI:47518; HSDB 7447; Terzolin; Teryzolin; EINECS 265-667-4; Onofin K; NSC 317629; BRN 4303081; 1-acetyl-4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imi
Indication
Disease Entry ICD 11 Status REF
Cushing disease 5A70 Phase 3 [1]
Affected Organisms
Humans and other mammals
ATC Code
H02CA04: COR-003
H02CA: Anticorticosteroids
H02C: ANTIADRENAL PREPARATIONS
H02: CORTICOSTEROIDS FOR SYSTEMIC USE
H: SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C26H28Cl2N4O4
Canonical SMILES
CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
InChI
InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1
InChIKey
XMAYWYJOQHXEEK-ZEQKJWHPSA-N
Cross-matching ID
PubChem CID
47576
ChEBI ID
CHEMBL295698
CAS Number
142128-57-2
UNII
2DJ8R0NT7K
DrugBank ID
DB05667
TTD ID
D0ES9U
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)