Details of the Drug

General Information of Drug (ID: DMIEOAP)

Drug Name

COR-003

Synonyms

Panfungol; Orifungal M; Nizoral; Ketozole; Normocort; 65277-42-1; Ketoisdin; Nizoral a-D; Sebazole; Levoketoconazole; UNII-2DJ8R0NT7K; Ketoconazolum [INN-Latin]; Ketoconazol [INN-Spanish]; Ketoconazole, (2S,4R)-; (2S,4R)-ketoconazole; 142128-57-2; 2DJ8R0NT7K; Ketocanazole; Ketoconazolum; Brizoral; CHEMBL295698; CHEBI:47518; HSDB 7447; Terzolin; Teryzolin; EINECS 265-667-4; Onofin K; NSC 317629; BRN 4303081; 1-acetyl-4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imi

Indication

Disease Entry	ICD 11	Status	REF
Cushing disease	5A70	Phase 3	[1]
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Affected Organisms

Humans and other mammals

ATC Code

H02CA04: COR-003

H02CA: Anticorticosteroids

H02C: ANTIADRENAL PREPARATIONS

H02: CORTICOSTEROIDS FOR SYSTEMIC USE

H: SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C26H28Cl2N4O4
Canonical SMILES: CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
InChI: 1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1
InChIKey: XMAYWYJOQHXEEK-ZEQKJWHPSA-N

Cross-matching ID

PubChem CID: 47576
ChEBI ID: CHEBI:47518
CAS Number: 142128-57-2
UNII: 2DJ8R0NT7K
DrugBank ID: DB05667
TTD ID: D0ES9U

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)