Details of the Drug

General Information of Drug (ID: DMIMPDL)

Drug Name
PCI-34051
Synonyms
PCI-34259; PCI-34260; PCI-40505; PCI-43744; PCI-45159; PCI-47634; PCI-48000; PCI-48001; PCI-48002; PCI-48003; PCI-48004; PCI-48006; PCI-48007; PCI-48008; PCI-48009; PCI-48010; PCI-48011; PCI-48012; PCI-48013; PCI-48018; PCI-48036; PCI-48039; HDAC 8 inhibitors (cancer/inflammation); HDAC 8 inhibitors (cancer/inflammation), Pharmacyclics
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 296.32
Logarithm of the Partition Coefficient (xlogp) 2.4
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C17H16N2O3
IUPAC Name
N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
Canonical SMILES
COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO
InChI
InChI=1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)
InChIKey
AJRGHIGYPXNABY-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
24753719
ChEBI ID
CHEBI:94192
CAS Number
950762-95-5
TTD ID
D0Q5MC

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase 8 (HDAC8) TTT6LFV HDAC8_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 4.9796 7.0989 2.5706 1.5963
EW-22 GDSC2 2.9432 5.7285 1.79 10.8531
EW-3 GDSC2 3.148 6.201 1.735 10.5527
CADO-ES1 GDSC2 3.1696 4.7525 2.4761 5.8156
EW-12 GDSC2 3.5769 6.0319 2.1731 6.5643
TC-71 GDSC2 3.7061 6.4611 2.0599 6.9379
HuO9 GDSC2 3.8991 6.9696 1.9539 7.1137
SK-ES-1 GDSC2 3.9442 7.3923 1.7792 8.0827
CHSA8926 GDSC2 3.9536 9.5257 0.7295 14.2801
NOS-1 [Human HNSCC] GDSC2 4.0846 8.2409 1.4655 9.6492
EW-16 GDSC2 4.1054 8.1322 1.5344 9.1815
A-673 GDSC2 4.1547 7.7082 1.7782 7.5824
ES7 GDSC2 4.2561 7.5703 1.9169 6.5076
EW-11 GDSC2 4.3116 8.0145 1.7405 7.4498
ES8 GDSC2 4.3312 7.3191 2.089 5.3094
SK-PN-DW GDSC2 4.3585 8.7908 1.3959 9.4045
SaOS-2 GDSC2 4.5184 7.8654 1.9533 5.7318
CHSA0108 GDSC2 4.562 7.1401 2.3206 3.5115
U2OS GDSC2 4.5686 9.0619 1.4128 8.8233
HOS GDSC2 4.631 7.7167 2.0961 4.6739
CAL-78 GDSC2 4.7761 10.8668 0.682 12.4828
EW-24 GDSC2 4.7766 9.3499 1.4171 8.343
HuO-3N1 GDSC2 4.8938 8.1613 2.0529 4.4444
ES4 GDSC2 4.9345 8.5496 1.8985 5.2468
ES5 GDSC2 4.9512 8.7483 1.8165 5.684
CHSA0011 GDSC2 5.2461 9.5319 1.6364 6.1593
ES6 GDSC2 5.2912 8.5623 2.1039 3.5234
CAL-72 GDSC2 5.3174 6.8483 2.8194 0.3879
EW-18 GDSC2 5.3553 7.6502 2.526 1.3983
MHH-ES-1 GDSC2 5.4206 10.9749 1.0712 8.9652
EW-7 GDSC2 5.5276 7.5017 2.6614 0.7428
G-292 clone A141B1 GDSC2 5.546 14.5578 -0.5677 16.8089
MG-63 GDSC2 5.5469 7.7647 2.5681 1.06
NY GDSC2 5.6119 17.106 -1.7673 21.3291
EW-13 GDSC2 6.1204 7.8506 2.7649 0.223
EW-1 GDSC2 6.2307 8.2626 2.6612 0.3911
U-CH2 GDSC2 6.4078 8.3991 2.6788 0.2972
H-EMC-SS GDSC2 6.5562 8.9362 2.5441 0.5354
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 157 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 2.3878 4.5426 1.827 12.584
MHH-CALL-2 GDSC2 1.0875 3.0851 0.9438 23.17
SU-DHL-5 GDSC2 1.3777 2.2728 1.3708 19.5454
HAL-01 GDSC2 1.4594 2.7858 1.4066 18.961
Loucy GDSC2 1.4902 3.6319 1.2305 19.7689
L-1236 GDSC2 1.5138 3.5833 1.2716 19.4364
SUP-B8 GDSC2 1.524 3.7453 1.2298 19.6221
KOPN-8 GDSC2 1.6174 3.6787 1.3533 18.5219
KE-37 GDSC2 1.6425 3.3626 1.4778 17.7226
H9 GDSC2 1.7157 4.9666 0.9521 20.3868
MOLT-16 GDSC2 1.8027 3.2236 1.6898 15.8367
P12-Ichikawa GDSC2 1.8683 4.5664 1.2819 17.8656
JeKo-1 GDSC2 1.9023 4.4217 1.3779 17.1684
NK-92MI GDSC2 2.0098 3.8565 1.7152 14.7743
MC116 GDSC2 2.06 5.753 0.9427 19.0898
697 GDSC2 2.1778 3.7921 1.9194 12.8913
P32/ISH GDSC2 2.2166 3.8098 1.9545 12.5251
OCI-Ly7 GDSC2 2.2205 4.0296 1.8731 12.9786
QIMR-WIL GDSC2 2.2285 4.1702 1.8241 13.2316
NU-DUL-1 GDSC2 2.3274 3.8416 2.0608 11.446
AMO1 GDSC2 2.3633 8.1973 0.0455 22.8289
EB2 GDSC2 2.3654 6.0211 1.1109 16.979
Farage GDSC2 2.391 4.5041 1.8475 12.4487
WSU-NHL GDSC2 2.4689 4.4984 1.9289 11.6597
CTV-1 GDSC2 2.4902 11.9667 -1.7117 29.4567
CTB-1 GDSC2 2.5307 4.8586 1.8244 12.062
JVM-3 GDSC2 2.5389 5.497 1.5286 13.8417
Namalwa GDSC2 2.5612 11.1307 -1.2333 27.6006
Jiyoye GDSC2 2.6133 5.2602 1.7135 12.4447
DoHH2 GDSC2 2.6912 3.9454 2.4011 7.9679
DEL GDSC2 2.7333 4.5024 2.1903 9.0825
IM-9 GDSC2 2.742 3.9069 2.4701 7.3568
CML-T1 GDSC2 2.7897 5.744 1.643 12.2734
HT GDSC2 2.8163 8.3031 0.3984 19.4737
NB4 GDSC2 2.8285 6.5674 1.2716 14.4258
CRO-AP2 GDSC2 2.8643 5.2043 1.9766 9.9473
TALL-1 [Human adult T-ALL] GDSC2 2.8692 5.4186 1.8759 10.5597
ST486 GDSC2 2.8772 5.7555 1.7172 11.5227
ML-2 GDSC2 2.9373 6.094 1.6036 12.0335
NALM-6 GDSC2 2.96 6.2503 1.5462 12.3171
RPMI-6666 GDSC2 2.968 5.0282 2.1584 8.4643
L-428 GDSC2 3.0063 5.6255 1.8976 9.9763
SR GDSC2 3.0126 4.6987 2.3614 7.045
L-540 GDSC2 3.0167 5.3055 2.0655 8.888
BE-13 GDSC2 3.0637 6.7093 1.4085 12.8391
BONNA-12 GDSC2 3.1078 4.992 2.3023 7.1062
RL GDSC2 3.1369 5.1891 2.23 7.4704
OCI-Ly19 GDSC2 3.1967 5.595 2.0794 8.2374
ARH-77 GDSC2 3.2288 5.9403 1.9344 9.0555
Daudi GDSC2 3.2444 4.4111 2.7114 4.0968
U-698-M GDSC2 3.246 5.7698 2.0341 8.3751
SU-DHL-1 GDSC2 3.2531 6.5907 1.6298 10.8926
SU-DHL-10 GDSC2 3.2938 5.2495 2.3346 6.3334
ALL-PO GDSC2 3.309 9.6923 0.126 19.339
GA-10 GDSC2 3.3476 6.0471 1.9806 8.4144
SU-DHL-6 GDSC2 3.3702 6.9597 1.5431 11.0876
RCH-ACV GDSC2 3.3861 5.9094 2.0813 7.6683
HEL GDSC2 3.3955 5.1416 2.4727 5.1669
CCRF-CEM GDSC2 3.4087 6.9047 1.6024 10.6088
SUP-HD1 GDSC2 3.4236 6.5358 1.7989 9.3397
SK-MM-2 GDSC2 3.441 6.188 1.9869 8.1089
P30/OHK GDSC2 3.4701 6.5699 1.8197 9.0782
CESS GDSC2 3.4936 7.8733 1.1877 12.8988
MOLT-13 GDSC2 3.4944 5.6926 2.2771 6.1301
SU-DHL-16 GDSC2 3.5195 5.2957 2.4944 4.6923
WIL2 NS GDSC2 3.5247 5.4423 2.4256 5.112
SUP-T1 GDSC2 3.5454 5.0339 2.6443 3.6829
LC4-1 GDSC2 3.5502 5.912 2.2119 6.3914
MHH-CALL-4 GDSC2 3.5743 5.6038 2.3839 5.2447
VAL GDSC2 3.5864 7.29 1.5538 10.4103
A3/Kawakami GDSC2 3.5887 5.3982 2.4969 4.4976
BALL-1 GDSC2 3.5999 6.2224 2.0964 6.9859
BC-1 GDSC2 3.6093 6.4821 1.9745 7.7263
Raji GDSC2 3.6236 7.107 1.6745 9.5612
RS4;11 GDSC2 3.6484 6.456 2.018 7.3503
PL-21 GDSC2 3.6713 5.856 2.333 5.3161
ALL-SIL GDSC2 3.675 5.9185 2.3048 5.4828
DND-41 GDSC2 3.703 5.7298 2.4189 4.7001
GDM-1 GDSC2 3.7157 6.955 1.8222 8.3974
MY-M12 GDSC2 3.725 7.3932 1.6116 9.6787
BL-41 GDSC2 3.7306 5.4304 2.5858 3.5983
Karpas-1106P GDSC2 3.7566 6.1857 2.2342 5.7207
SU-DHL-4 GDSC2 3.7745 5.5895 2.5396 3.7821
VL51 GDSC2 3.8192 8.9227 0.9244 13.5383
PF-382 GDSC2 3.8211 7.7362 1.5157 10.0143
Reh GDSC2 3.827 5.5919 2.5753 3.445
Karpas-299 GDSC2 3.8407 7.4302 1.6825 8.9391
SUP-M2 GDSC2 3.8442 5.8725 2.4513 4.1662
KMS-11 GDSC2 3.8452 7.607 1.5983 9.446
BC-3 GDSC2 3.9003 6.0558 2.4019 4.343
OCI-AML-3 GDSC2 3.9252 7.1458 1.8865 7.4671
Jurkat GDSC2 3.9448 5.6804 2.6127 2.9697
LAMA-84 GDSC2 4.0008 10.1087 0.4763 15.5375
SU-DHL-8 GDSC2 4.0062 6.6318 2.1968 5.3618
MLMA GDSC2 4.032 10.4131 0.3493 16.1265
KMS-12-BM GDSC2 4.0326 6.4049 2.325 4.5202
SCC-3 GDSC2 4.0337 5.9026 2.5657 3.071
ROS-50 GDSC2 4.0517 6.2882 2.3941 4.0606
HC-1 GDSC2 4.0665 7.825 1.6568 8.5329
EoL-1 GDSC2 4.0711 6.4263 2.341 4.3399
Ku812 GDSC2 4.1085 6.503 2.3295 4.3303
KM-H2 GDSC2 4.1244 8.2945 1.4686 9.5319
Ramos.2G6.4C10 GDSC2 4.1292 9.4925 0.8809 12.9666
OPM-2 GDSC2 4.1464 5.9658 2.6076 2.6129
NCI-H929 GDSC2 4.1476 6.3058 2.4492 3.5354
Hs 445 GDSC2 4.1669 6.2739 2.4767 3.3355
RC-K8 GDSC2 4.175 5.7084 2.7423 1.8077
THP-1 GDSC2 4.1771 6.88 2.1953 4.9949
OCI-AML-2 GDSC2 4.2121 7.1185 2.1045 5.4683
TK [Human B-cell lymphoma] GDSC2 4.2282 6.1571 2.5696 2.6838
RPMI-8226 GDSC2 4.3313 6.8267 2.3224 3.9245
Karpas-422 GDSC2 4.3755 7.7378 1.9184 6.2384
Karpas-45 GDSC2 4.4147 7.0293 2.2806 4.01
OCI-AML-5 GDSC2 4.4264 5.9034 2.794 1.1925
MN-60 GDSC2 4.4311 6.2372 2.652 1.9022
CA46 GDSC2 4.4662 7.3234 2.1755 4.5255
KCL-22 GDSC2 4.4977 7.2398 2.2346 4.1208
DB GDSC2 4.5154 7.5347 2.1077 4.8273
MOLM-13 GDSC2 4.5174 7.3347 2.2028 4.2688
MOLM-16 GDSC2 4.5364 8.3285 1.7441 6.9353
Kasumi-1 GDSC2 4.5535 8.5754 1.6372 7.5326
GR-ST GDSC2 4.556 8.7162 1.5711 7.9185
HDLM-2 GDSC2 4.6033 6.9981 2.41 2.9416
JVM-2 GDSC2 4.6106 9.8585 1.0554 10.7946
RPMI-8866 GDSC2 4.6168 6.6757 2.5616 2.1064
MM1.S GDSC2 4.6295 7.0786 2.389 3.015
L-363 GDSC2 4.6597 9.9918 1.0254 10.8512
MEG-01 GDSC2 4.805 7.0689 2.4924 2.1994
KY821 GDSC2 4.8454 8.3214 1.949 5.1219
SIG-M5 GDSC2 4.8905 13.1774 -0.3675 17.4385
Karpas-620 GDSC2 4.9632 6.5839 2.7718 0.7595
Karpas-231 GDSC2 4.9875 6.6107 2.7721 0.7396
DG-75 GDSC2 5.0019 7.7591 2.2976 2.9306
SKM-1 GDSC2 5.0839 6.5419 2.8391 0.4522
NOMO-1 GDSC2 5.0985 6.6186 2.8164 0.5129
ME1 GDSC2 5.1214 6.3428 2.9258 0.2149
HL-60 GDSC2 5.1944 6.4785 2.9051 0.2333
MHH-PREB-1 GDSC2 5.2152 7.0269 2.7099 0.7934
EM-2 GDSC2 5.2416 6.6752 2.8527 0.3366
A4/Fukuda GDSC2 5.3053 6.7786 2.84 0.3406
SUP-B15 GDSC2 5.3055 6.976 2.7674 0.542
JURL-MK1 GDSC2 5.3494 7.0545 2.7561 0.5512
OCI-M1 GDSC2 5.3544 6.7595 2.8655 0.2619
MOLP-8 GDSC2 5.416 6.8915 2.8417 0.2917
LP-1 GDSC2 5.4552 7.0902 2.7853 0.4131
ATN-1 GDSC2 5.4838 7.0616 2.8067 0.3465
TUR GDSC2 5.5062 7.1541 2.782 0.3982
K-562 GDSC2 5.534 7.1468 2.7953 0.3531
EJM GDSC2 5.5898 7.2525 2.7788 0.37
U266B1 GDSC2 5.6642 7.9059 2.5647 0.9819
KMOE-2 GDSC2 5.7593 7.6558 2.6984 0.4996
Granta-519 GDSC2 5.9442 7.6705 2.7635 0.2752
KG-1 GDSC2 5.9495 7.8472 2.7029 0.4041
JJN-3 GDSC2 6.0596 7.5557 2.8439 0.1215
MOLT-4 GDSC2 6.0621 7.3643 2.9082 0.0581
JSC-1 GDSC2 6.129 7.938 2.7377 0.2687
HH [Human lymphoma] GDSC2 6.3492 8.5289 2.6111 0.4598
⏷ Show the Full List of 157 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 3.95 12.3628 -0.6864 21.2677
KYSE-50 GDSC2 4.3562 7.3748 2.0791 5.3165
KYAE-1 GDSC2 4.488 6.6393 2.5048 2.6071
SK-GT-4 GDSC2 5.0977 8.9776 1.8013 5.5015
HCE-4 GDSC2 5.1549 15.8501 -1.4879 21.3759
FLO-1 GDSC2 5.4574 8.3389 2.2902 2.3569
ESO-26 GDSC2 5.6884 7.953 2.5569 0.9918
ESO-51 GDSC2 5.7339 7.8714 2.6077 0.7856
OACM5.1 C GDSC2 5.8817 8.8442 2.29 1.8873
OACP4 C GDSC2 6.0965 8.1444 2.6524 0.4648
TE-12 GDSC2 6.3171 9.4497 2.249 1.65
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 4.0589 6.7238 2.1891 5.2903
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LA-N-6 GDSC2 2.2737 5.1496 1.4351 15.3754
SJNB-14 GDSC2 2.485 5.3277 1.558 13.8549
MHH-NB-11 GDSC2 2.6017 4.7171 1.9604 10.9707
SiMa GDSC2 2.756 6.1498 1.4125 13.8072
KP-N-YS GDSC2 3.0316 5.0735 2.1938 8.0335
SJNB-13 GDSC2 3.1807 5.5992 2.0636 8.386
NB69 GDSC2 3.1917 11.5249 -0.8886 24.2949
CHP-126 GDSC2 3.2139 5.0431 2.3698 6.35
NB(TU)1 GDSC2 3.231 6.5491 1.632 10.9453
SK-N-DZ GDSC2 3.3841 5.4112 2.3286 6.1104
SK-N-MC-IXC GDSC2 3.3995 4.7526 2.6702 3.9064
Kelly GDSC2 3.4065 6.0296 2.0379 7.8847
SJNB-17 GDSC2 3.4566 7.0691 1.5594 10.7389
CHP-134 GDSC2 3.506 6.045 2.1105 7.1496
NH-12 GDSC2 3.6274 5.7361 2.359 5.2641
SJNB-5 GDSC2 3.6593 6.3746 2.0668 7.0153
KP-N-YN GDSC2 3.6723 7.7251 1.4051 11.0866
IMR-5 GDSC2 3.8864 9.9506 0.4655 15.9059
CHP-212 GDSC2 3.9804 6.6521 2.1686 5.5937
TGW GDSC2 4.0349 8.9048 1.1001 11.947
SJNB-10 GDSC2 4.1958 8.2533 1.5412 8.922
SK-N-BE(2)-M17 GDSC2 4.2247 9.1911 1.1015 11.4579
GOTO GDSC2 4.3168 7.1535 2.1583 4.9247
SJNB-6 GDSC2 4.6101 6.8735 2.47 2.6031
SJNB-7 GDSC2 4.7689 7.8797 2.1063 4.3627
KP-N-RT-BM-1 GDSC2 4.7975 6.8898 2.5658 1.8399
GI-ME-N GDSC2 5.8067 9.0682 2.16 2.5564
SK-N-AS GDSC2 6.7779 17.4004 -1.0871 16.3911
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 3.9067 6.1887 2.3418 4.6974
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUB-M GDSC2 1.9792 10.0987 -1.2416 29.6175
HCC1599 GDSC2 2.812 5.1314 1.9636 10.2059
YMB-1-E GDSC2 3.2298 5.6673 2.0716 8.1872
MDA-MB-468 GDSC2 3.3287 7.1713 1.4029 12.0719
HCC1569 GDSC2 3.645 8.573 0.9605 13.8104
CAL-51 GDSC2 3.7199 6.7578 1.9234 7.7557
Evsa-T GDSC2 3.8136 5.7004 2.5134 3.8543
AU565 GDSC2 3.8796 6.0264 2.4016 4.3918
HCC1428 GDSC2 4.1761 7.5376 1.8765 6.9335
CAL-85-1 GDSC2 4.2707 9.35 1.0574 11.599
MDA-MB-453 GDSC2 4.3968 6.9132 2.3235 3.794
EFM-19 GDSC2 4.4436 7.6614 2.0008 5.6032
HCC2218 GDSC2 4.6197 8.2296 1.8471 6.1525
HCC38 GDSC2 4.6863 6.6553 2.608 1.7746
DU4475 GDSC2 4.7428 6.3385 2.7689 0.9637
HDQ-P1 GDSC2 4.8414 6.7298 2.6558 1.3593
HCC1500 GDSC2 4.884 9.7038 1.3203 8.6723
MDA-MB-361 GDSC2 4.9277 9.5145 1.44 7.8939
Hs 578T GDSC2 4.9804 7.3431 2.4673 2.0912
COLO 824 GDSC2 5.0055 7.4744 2.424 2.2742
BT-20 GDSC2 5.0095 7.5229 2.4052 2.3639
HCC1806 GDSC2 5.0113 6.7744 2.7183 0.9257
T-47D GDSC2 5.0447 9.9776 1.2971 8.4682
BT-474 GDSC2 5.045 7.1139 2.5966 1.4059
MFM-223 GDSC2 5.0654 8.1471 2.1608 3.564
HCC2157 GDSC2 5.0846 6.877 2.7108 0.8928
CAL-120 GDSC2 5.0861 6.4575 2.8711 0.3604
HCC70 GDSC2 5.1571 7.4099 2.529 1.5887
MDA-MB-330 GDSC2 5.1973 9.6581 1.547 6.7523
MCF-7 GDSC2 5.2071 10.0473 1.3706 7.7266
HCC1143 GDSC2 5.2618 9.2258 1.7872 5.2903
HCC1937 GDSC2 5.3348 7.2388 2.6798 0.8129
CAMA-1 GDSC2 5.3997 7.5436 2.5893 1.1
ZR-75-30 GDSC2 5.4104 7.5322 2.5986 1.0548
HCC1419 GDSC2 5.4518 7.9739 2.4399 1.6733
EFM-192A GDSC2 5.4741 7.1428 2.7735 0.4354
JIMT-1 GDSC2 5.6557 7.2065 2.8199 0.2549
UACC-893 GDSC2 5.666 18.9159 -2.6182 23.931
HCC1954 GDSC2 5.6881 7.6621 2.6675 0.6253
MDA-MB-157 GDSC2 5.6925 7.7226 2.6467 0.6866
MDA-MB-231 GDSC2 5.8326 7.6362 2.7339 0.378
HCC1187 GDSC2 5.8585 7.4955 2.7932 0.2443
MRK-nu-1 GDSC2 5.9253 7.3935 2.852 0.1349
MDA-MB-436 GDSC2 5.9693 7.8581 2.7065 0.3877
MDA-MB-415 GDSC2 5.9923 7.9006 2.7001 0.3937
BT-549 GDSC2 6.2542 8.3473 2.6399 0.4304
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med GDSC2 3.513 7.1253 1.577 10.4705
8-MG-BA GDSC2 4.0261 6.8464 2.1065 5.8702
KS-1 [Human Krukenberg tumour] GDSC2 4.0641 10.2927 0.4341 15.5936
KALS-1 GDSC2 4.1302 6.2037 2.4861 3.3516
SF268 GDSC2 4.1463 6.9024 2.1635 5.2538
PFSK-1 GDSC2 4.1595 6.7483 2.2465 4.7231
LN-18 GDSC2 4.2733 5.6009 2.8436 1.1413
SF126 GDSC2 4.3055 6.0662 2.6569 2.0669
AM-38 GDSC2 4.3163 7.6487 1.9207 6.3525
U-251MG GDSC2 4.3649 6.8846 2.3167 3.8936
GaMG GDSC2 4.3718 7.0659 2.2359 4.3543
KINGS-1 GDSC2 4.4065 9.0749 1.2916 9.9065
U-87MG ATCC GDSC2 4.4286 7.616 2.0124 5.5652
D-336MG GDSC2 4.4594 7.2851 2.1892 4.4583
SF539 GDSC2 4.4795 11.4818 0.1619 15.9232
SF295 GDSC2 4.4823 6.3061 2.6499 1.8394
Hs 683 GDSC2 4.5129 6.0674 2.7687 1.2097
GB-1 GDSC2 4.5172 6.2416 2.6967 1.5535
YKG-1 GDSC2 4.5363 6.356 2.6574 1.7259
D-392MG GDSC2 4.7406 14.3288 -1.0485 20.7001
H4 GDSC2 4.754 14.6973 -1.2208 21.3385
GI-1 GDSC2 4.7565 8.7038 1.7121 6.667
Onda 10 GDSC2 4.8366 9.5518 1.361 8.5393
SNB-75 GDSC2 4.9194 10.2905 1.0623 10.0596
DK-MG GDSC2 4.9546 7.3765 2.4392 2.2657
D-502MG GDSC2 5.0264 14.5838 -0.9593 19.6494
Daoy GDSC2 5.1022 12.1655 0.2816 13.8245
NMC-G1 GDSC2 5.126 6.6203 2.827 0.4647
KNS-81-FD GDSC2 5.1577 17.4639 -2.2835 24.0481
D-542MG GDSC2 5.1783 6.8243 2.7719 0.6056
CAS-1 GDSC2 5.2237 6.7115 2.8325 0.3979
M059J GDSC2 5.2475 7.4764 2.5455 1.4213
LN-405 GDSC2 5.2722 7.5104 2.5434 1.4054
U-118MG GDSC2 5.2782 7.2954 2.6326 1.0336
42-MG-BA GDSC2 5.2999 8.7215 2.038 3.8598
DBTRG-05MG GDSC2 5.3034 7.2613 2.6573 0.9188
A-172 GDSC2 5.352 9.8313 1.5633 6.375
D-263MG GDSC2 5.3658 6.8878 2.8239 0.3543
SK-MG-1 GDSC2 5.4413 7.4682 2.6373 0.8866
Becker GDSC2 5.4659 7.3735 2.6842 0.7077
D-423MG GDSC2 5.4859 7.9761 2.4553 1.5713
D-247MG GDSC2 5.5349 7.6667 2.601 0.9474
SW1088 GDSC2 5.5934 8.4373 2.3175 2.0705
YH-13 GDSC2 5.6603 7.0898 2.8621 0.177
D-566MG GDSC2 5.6823 7.2864 2.8017 0.2833
T98G GDSC2 5.8779 7.7586 2.7073 0.4229
LN-229 GDSC2 5.8808 7.6575 2.7446 0.3356
KNS-42 GDSC2 6.2307 7.6322 2.8765 0.0666
D-245MG GDSC2 6.2818 9.1317 2.3583 1.2644
ONS-76 GDSC2 6.3093 14.4296 0.0169 12.5691
Onda 11 GDSC2 6.5855 8.8673 2.5799 0.4404
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC2 5.8842 8.2758 2.5169 0.9912
TGBC24TKB GDSC2 5.9887 8.1141 2.6212 0.5975
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC2 3.8678 6.1837 2.3165 4.9429
KLE GDSC2 4.0971 10.7478 0.2336 16.5516
RL95-2 GDSC2 4.3584 7.8997 1.8286 6.8149
MFE-280 GDSC2 4.5196 8.4875 1.6563 7.4928
EN GDSC2 4.654 6.7936 2.5303 2.2166
MFE-296 GDSC2 4.7723 7.0327 2.4904 2.2551
MFE-319 GDSC2 5.8807 7.476 2.808 0.2117
AN3-CA GDSC2 6.3931 14.5951 -0.0066 12.5162
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-26A GDSC2 3.5039 5.7783 2.2419 6.3262
Caki-1 GDSC2 3.7427 6.389 2.1234 6.4474
RCC10RGB GDSC2 3.7853 7.1953 1.7565 8.6244
A-498 GDSC2 4.0033 7.7242 1.6596 8.6709
UO-31 GDSC2 4.0563 6.229 2.4255 3.8618
RXF 393L GDSC2 4.0905 6.8554 2.1475 5.4738
786-O GDSC2 4.0928 6.714 2.2174 5.0428
KTCTL-13 GDSC2 4.1759 9.046 1.1367 11.3744
KTCTL-1M GDSC2 4.2122 6.5921 2.356 3.9598
SW13 GDSC2 4.376 7.4386 2.0619 5.3784
KTCTL-140 GDSC2 4.3771 6.8 2.3639 3.596
NCC010 GDSC2 4.4328 10.0762 0.82 12.5462
769-P GDSC2 4.5579 8.1261 1.8554 6.2305
ACHN GDSC2 4.5602 7.8297 1.9976 5.386
CAL-54 GDSC2 4.7529 13.1016 -0.4326 18.0674
LB1047-RCC GDSC2 4.7874 7.6727 2.2125 3.732
BB65-RCC GDSC2 4.8931 12.7001 -0.1309 16.3351
A-704 GDSC2 4.9494 7.063 2.5704 1.6318
VMRC-RCW GDSC2 5.0989 6.9562 2.6859 0.9779
KTCTL-21 GDSC2 5.1934 12.0755 0.3897 13.0688
NCC021 GDSC2 5.2788 9.0377 1.8833 4.7314
BFTC-909 GDSC2 5.2942 7.0044 2.7521 0.5964
SN12C GDSC2 5.31 7.2928 2.6479 0.9488
LB996-RCC GDSC2 5.7359 10.5293 1.4759 6.1799
KMRC-20 GDSC2 5.8021 12.3413 0.6738 10.3255
VMRC-RCZ GDSC2 5.8043 7.5994 2.7363 0.3837
TK-10 GDSC2 5.8385 8.4688 2.4212 1.3843
OS-RC-2 GDSC2 5.8471 7.3225 2.8487 0.155
HA7-RCC GDSC2 5.884 8.0433 2.6051 0.7018
SW156 GDSC2 5.9088 7.8487 2.6867 0.4609
KTCTL-195 GDSC2 5.9295 7.7708 2.7226 0.3663
LB2241-RCC GDSC2 5.9412 7.8434 2.7011 0.4117
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCT 15 GDSC2 2.8592 4.8198 2.1594 8.8258
HT-55 GDSC2 3.4534 5.9156 2.133 7.1528
SNU-407 GDSC2 3.6604 5.9258 2.2902 5.6114
LS513 GDSC2 3.8367 6.2305 2.2711 5.297
SNU-C5 GDSC2 3.9079 6.6947 2.0954 6.2157
HT-29 GDSC2 3.9569 5.8006 2.5635 3.2394
LoVo GDSC2 3.9595 7.3715 1.8008 7.9113
C2BBe1 GDSC2 4.0198 8.5579 1.2604 11.0405
HT115 GDSC2 4.1685 6.1737 2.5247 3.0516
CL-11 GDSC2 4.2048 7.6679 1.8335 7.1298
RCM-1 [Human ESC] GDSC2 4.2204 10.0714 0.6636 13.9445
LS411N GDSC2 4.2522 5.7617 2.7623 1.5835
KM12 GDSC2 4.2571 7.946 1.7353 7.6054
COLO 320HSR GDSC2 4.3226 6.0413 2.6778 1.9269
SW48 GDSC2 4.389 6.4855 2.5162 2.7074
SNU-C2B GDSC2 4.4478 9.8207 0.9564 11.7426
CaR-1 GDSC2 4.5253 7.3426 2.2041 4.2463
HCT 116 GDSC2 4.5312 6.3628 2.6518 1.7615
SW1116 GDSC2 4.5837 7.5407 2.1485 4.4591
SW626 GDSC2 4.5988 8.8486 1.5368 8.0273
CW-2 GDSC2 4.6405 6.9135 2.4695 2.5587
MDST8 GDSC2 4.6474 6.1742 2.7905 0.9653
SW1463 GDSC2 4.8583 7.3082 2.4167 2.515
SW837 GDSC2 4.9898 7.897 2.2294 3.3121
COLO205 GDSC2 5.0363 6.4754 2.8445 0.4629
SW620 GDSC2 5.0581 9.5393 1.5137 7.2095
RKO GDSC2 5.0661 6.8106 2.7287 0.8398
LS180 GDSC2 5.1715 6.8077 2.7753 0.5989
HCC2998 GDSC2 5.2022 7.1347 2.6619 0.9838
SNU-61 GDSC2 5.2037 6.8997 2.7539 0.6487
SW1417 GDSC2 5.2168 7.1904 2.6465 1.0318
SNU-1040 GDSC2 5.2953 7.0365 2.7404 0.6333
SW948 GDSC2 5.4442 6.8055 2.8825 0.1991
GP5d GDSC2 5.4467 6.9682 2.826 0.3158
CCK-81 GDSC2 5.4611 8.0086 2.4301 1.7065
NCI-H747 GDSC2 5.4964 7.5996 2.6103 0.9428
SK-CO-1 GDSC2 5.5252 7.1948 2.7746 0.4086
SNU-C1 GDSC2 5.5278 7.2194 2.7667 0.428
SNU-175 GDSC2 5.6296 7.8189 2.5833 0.9408
LS1034 GDSC2 5.6575 7.0621 2.8706 0.164
NCI-H508 GDSC2 5.663 7.3322 2.7781 0.3421
LS123 GDSC2 5.6868 7.6789 2.6607 0.6467
T84 GDSC2 5.718 7.7295 2.6545 0.6473
COLO 678 GDSC2 5.7479 7.2415 2.8412 0.1896
SNU-81 GDSC2 5.8938 7.3991 2.8391 0.1592
NCI-H716 GDSC2 6.0256 7.8203 2.741 0.2939
SNU-283 GDSC2 6.0904 7.4411 2.8924 0.0679
DiFi GDSC2 6.2143 8.7065 2.4923 0.8556
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 5.799 7.5285 2.7596 0.3324
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-449 GDSC2 3.5236 5.7312 2.281 6.0266
SNU-398 GDSC2 3.6148 6.6584 1.8911 8.2347
Hep-G2/C3A GDSC2 3.7467 5.304 2.6587 3.1134
JHH-6 GDSC2 3.7687 6.2932 2.1902 5.9652
Hep 3B2.1-7 GDSC2 3.8048 8.6139 1.0668 12.7497
JHH-1 GDSC2 4.019 6.5476 2.2467 5.0275
HuH-1 GDSC2 4.0909 6.1933 2.4654 3.5524
Huh-7 GDSC2 4.2444 6.6384 2.355 3.9017
HLE GDSC2 4.3602 7.1211 2.2023 4.5754
JHH-7 GDSC2 4.3745 6.6586 2.4279 3.2324
SK-HEP-1 GDSC2 4.8558 6.3453 2.8177 0.6734
JHH-4 GDSC2 5.0624 11.1676 0.7378 11.5307
SNU-423 GDSC2 5.5484 16.4668 -1.4999 20.5203
SNU-387 GDSC2 5.686 15.1781 -0.7702 17.3621
JHH-2 GDSC2 5.8612 7.6366 2.7446 0.3427
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 166 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC33 GDSC2 2.5334 6.5569 1.008 16.9948
NCI-H211 GDSC2 3.0153 5.521 1.9575 9.5715
NCI-H1915 GDSC2 3.1302 7.8563 0.8931 15.7164
NCI-H82 GDSC2 3.2926 5.1966 2.36 6.1758
NCI-H1876 GDSC2 3.3137 5.4136 2.2692 6.6891
BEN GDSC2 3.3501 6.4849 1.7639 9.7701
NCI-H2227 GDSC2 3.4644 5.5255 2.3365 5.8367
NCI-H748 GDSC2 3.4693 6.8741 1.6671 10.0342
NCI-H146 GDSC2 3.4885 6.4998 1.8696 8.714
NCI-H290 GDSC2 3.4951 5.7178 2.2651 6.2039
SHP-77 GDSC2 3.5372 6.7504 1.7836 9.1178
COR-L321 GDSC2 3.5964 5.3734 2.515 4.3643
LK-2 GDSC2 3.6206 5.3875 2.5263 4.2331
Lu-139 GDSC2 3.7373 5.7947 2.4124 4.6577
LCLC-103H GDSC2 3.7388 6.703 1.965 7.4473
NCI-H2122 GDSC2 3.752 5.5555 2.5401 3.8309
COR-L303 GDSC2 3.7658 7.0109 1.8331 8.1996
NCI-H526 GDSC2 3.7663 6.5416 2.0658 6.7478
NCI-H2795 GDSC2 3.8135 18.1202 -3.6717 30.9197
NCI-H209 GDSC2 3.814 6.611 2.0673 6.6194
LB647-SCLC GDSC2 3.9456 6.8548 2.0445 6.4412
COR-L311 GDSC2 3.9568 6.296 2.325 4.6873
RERF-LC-MS GDSC2 3.9918 11.6881 -0.3168 19.5149
NCI-H2141 GDSC2 3.9931 5.9707 2.5065 3.5067
CPC-N GDSC2 4.0155 5.834 2.5862 2.9857
NCI-H3122 GDSC2 4.0278 6.9851 2.0401 6.2746
NCI-H810 GDSC2 4.0291 6.3527 2.3477 4.3896
NCI-H1651 GDSC2 4.0462 9.7326 0.6984 14.2066
NCI-H647 GDSC2 4.0549 6.1452 2.4645 3.6311
COLO 668 GDSC2 4.0756 6.18 2.4617 3.6056
NCI-H838 GDSC2 4.0816 7.3968 1.8777 7.1456
NCI-H1993 GDSC2 4.0915 7.2135 1.9742 6.5312
NCI-H1792 GDSC2 4.094 6.2127 2.4582 3.5889
SBC-5 GDSC2 4.0954 7.2722 1.9484 6.6805
SBC-1 GDSC2 4.1275 6.4183 2.3827 3.9717
NCI-H1781 GDSC2 4.1454 10.2582 0.5139 14.9524
NCI-H1105 GDSC2 4.1641 6.3016 2.4619 3.4283
HCC78 GDSC2 4.177 10.1366 0.5984 14.4132
COR-L105 GDSC2 4.1969 10.3987 0.4836 14.9799
NCI-H2085 GDSC2 4.2575 7.7793 1.8166 7.1127
IA-LM GDSC2 4.2709 6.6939 2.3461 3.9024
NCI-H460 GDSC2 4.2774 8.0343 1.7067 7.7316
NCI-H2030 GDSC2 4.278 6.2089 2.576 2.5605
NCI-H841 GDSC2 4.2891 6.5789 2.4116 3.4833
NCI-H513 GDSC2 4.3131 6.4237 2.4986 2.9379
Lu-65 GDSC2 4.3175 6.8023 2.325 3.936
NCI-H1836 GDSC2 4.3532 6.1958 2.6263 2.1582
EPLC-272H GDSC2 4.3607 6.9011 2.3062 3.9627
SK-MES-1 GDSC2 4.3711 8.3662 1.6117 8.0894
Lu-135 GDSC2 4.3798 6.3461 2.574 2.4016
NCI-H2029 GDSC2 4.3831 7.0521 2.2497 4.2508
DMS 53 GDSC2 4.3848 9.0173 1.3041 9.8843
NCI-H250 GDSC2 4.4028 6.5975 2.4732 2.9252
HCC44 GDSC2 4.457 6.836 2.3966 3.2645
NCI-H2810 GDSC2 4.4643 7.1429 2.2588 4.0429
NCI-H2171 GDSC2 4.4684 6.3435 2.6257 1.9857
NCI-H720 GDSC2 4.4693 6.0157 2.7684 1.2632
Calu-3 GDSC2 4.4778 7.3445 2.173 4.5176
NCI-H2373 GDSC2 4.4811 7.9771 1.8751 6.2732
Lu-134-A GDSC2 4.4945 7.1016 2.297 3.7666
NCI-H196 GDSC2 4.4968 7.6388 2.0465 5.224
LOU-NH91 GDSC2 4.5336 7.6387 2.0705 5.0102
EMC-BAC-2 GDSC2 4.5396 9.714 1.0751 10.8484
SBC-3 GDSC2 4.5549 8.4338 1.7062 7.1206
Ms-1 GDSC2 4.5706 6.4544 2.6332 1.8023
NCI-H1581 GDSC2 4.5751 8.3456 1.7621 6.7471
NCI-H740 GDSC2 4.5791 7.2017 2.3027 3.5828
NCI-H358 GDSC2 4.5915 9.0808 1.4196 8.7324
HOP-62 GDSC2 4.6028 7.23 2.3041 3.5335
NCI-H2291 GDSC2 4.6108 6.7602 2.5209 2.3291
NCI-H1770 GDSC2 4.6394 6.8571 2.494 2.4295
NCI-H23 GDSC2 4.6833 7.8598 2.0623 4.7714
NCI-H2722 GDSC2 4.6892 7.0757 2.4249 2.7241
NCI-H2081 GDSC2 4.7033 7.2257 2.3657 3.0237
NCI-H446 GDSC2 4.7049 8.4992 1.7753 6.402
SW1271 GDSC2 4.7179 7.317 2.333 3.1793
NCI-H522 GDSC2 4.7237 11.261 0.4513 13.8357
NCI-H322M GDSC2 4.7249 8.7965 1.6471 7.1118
NCI-H2804 GDSC2 4.7298 11.2462 0.463 13.7597
NCI-H1299 GDSC2 4.7354 8.6929 1.7033 6.761
NCI-H2803 GDSC2 4.7467 7.4094 2.308 3.2698
NCI-H345 GDSC2 4.7698 5.9716 2.9238 0.3757
NCI-H3255 GDSC2 4.7736 7.9224 2.0895 4.4498
Calu-6 GDSC2 4.8008 10.3705 0.9411 11.0019
NCI-H2731 GDSC2 4.8149 6.97 2.5405 1.943
DMS 79 GDSC2 4.8319 6.7442 2.6451 1.4191
RERF-LC-Sq1 GDSC2 4.8334 8.5396 1.8395 5.7749
NCI-H2196 GDSC2 4.8395 7.3114 2.4049 2.6043
Lu-165 GDSC2 4.8409 6.9323 2.5703 1.7633
IST-SL2 GDSC2 4.8617 7.9361 2.1367 4.0295
LC-2/ad GDSC2 4.864 7.9567 2.1287 4.0702
NCI-H1650 GDSC2 4.8787 6.9794 2.5697 1.7193
HCC366 GDSC2 4.8794 10.3427 1.0095 10.4436
NCI-H727 GDSC2 4.8878 9.6761 1.3361 8.5735
CAL-12T GDSC2 4.8896 12.1448 0.139 15.034
NCI-H1694 GDSC2 4.8991 6.8107 2.6506 1.3198
NCI-H2444 GDSC2 4.9271 5.9793 2.9817 0.1654
COR-L32 GDSC2 4.9391 7.8047 2.2417 3.3245
PC-14 GDSC2 4.9434 7.3658 2.4379 2.2878
NCI-H226 GDSC2 4.9739 8.0571 2.1482 3.7787
NCI-H1963 GDSC2 4.9778 7.1968 2.5284 1.7973
COR-L23 GDSC2 4.9787 6.3344 2.8735 0.4087
SW1573 GDSC2 5.0164 8.2794 2.0725 4.126
NCI-H2461 GDSC2 5.0313 8.0886 2.1674 3.5821
NCI-H1435 GDSC2 5.0803 6.9614 2.6753 1.0366
NCI-H2369 GDSC2 5.09 6.6044 2.8182 0.5124
RERF-LC-KJ GDSC2 5.0935 12.9437 -0.1043 15.7356
ABC-1 GDSC2 5.104 9.4852 1.5687 6.8077
KNS-62 GDSC2 5.1061 11.2415 0.7324 11.463
HOP-92 GDSC2 5.167 7.9124 2.3208 2.5783
LCLC-97TM1 GDSC2 5.173 8.1379 2.2255 3.0591
NCI-H1975 GDSC2 5.1768 7.2009 2.6238 1.1586
HARA [Human squamous cell lung carcinoma] GDSC2 5.1881 7.8618 2.3538 2.3849
NCI-H1092 GDSC2 5.2182 6.6966 2.8358 0.3915
NCI-H1568 GDSC2 5.2297 11.5931 0.648 11.6434
DMS 114 GDSC2 5.2304 7.8936 2.3623 2.2888
NCI-H2110 GDSC2 5.2331 7.7283 2.4339 1.942
NCI-H2818 GDSC2 5.2403 7.3218 2.6047 1.1786
NCI-H510A GDSC2 5.3124 8.0687 2.3303 2.3421
NCI-H524 GDSC2 5.3264 7.0243 2.7579 0.5588
SK-LU-1 GDSC2 5.3327 7.5346 2.5621 1.2686
NCI-H1734 GDSC2 5.3376 7.5588 2.5546 1.2949
NCI-H2595 GDSC2 5.3558 7.8145 2.4589 1.6897
NCI-H2869 GDSC2 5.3679 13.3391 -0.1009 15.0926
NCI-H2170 GDSC2 5.3756 9.5348 1.7143 5.4972
NCI-H650 GDSC2 5.3821 10.5271 1.2575 8.0165
NCI-H2591 GDSC2 5.4296 9.0517 1.9644 4.0528
NCI-H1869 GDSC2 5.4382 9.4765 1.7783 5.0411
ChaGo-K-1 GDSC2 5.4524 11.4432 0.8701 9.9907
NCI-H1436 GDSC2 5.4566 7.1731 2.7554 0.4942
NCI-H1944 GDSC2 5.4706 9.1963 1.9232 4.2088
EKVX GDSC2 5.4733 8.5663 2.2013 2.7705
UMC-11 GDSC2 5.4886 7.0824 2.8011 0.3582
A-427 GDSC2 5.5482 15.3878 -0.9713 18.493
NCI-H1666 GDSC2 5.5484 10.3245 1.4564 6.6121
NCI-H1048 GDSC2 5.5496 7.521 2.6633 0.722
NCI-H1755 GDSC2 5.5714 12.6078 0.3935 12.2299
DMS 273 GDSC2 5.5963 12.231 0.5905 11.1702
NCI-H1793 GDSC2 5.6025 10.4161 1.4472 6.5661
NCI-H2172 GDSC2 5.6149 7.1527 2.8237 0.2604
VMRC-LCD GDSC2 5.6166 7.614 2.6561 0.7031
NCI-H596 GDSC2 5.651 8.2728 2.413 1.5895
NCI-H1563 GDSC2 5.6613 13.8435 -0.1399 14.6306
NCI-H2087 GDSC2 5.6725 8.3291 2.4003 1.6226
IST-SL1 GDSC2 5.6737 7.4866 2.7265 0.4655
Lu-99A GDSC2 5.6985 7.9119 2.5771 0.9128
LC-1/sq GDSC2 5.7048 8.0553 2.5243 1.099
NCI-H292 GDSC2 5.7185 7.2016 2.8445 0.1917
EMC-BAC-1 GDSC2 5.7442 8.5517 2.3437 1.7935
HCC827 GDSC2 5.7706 7.3631 2.8073 0.2439
NCI-H1355 GDSC2 5.7879 11.0377 1.2741 7.175
NCI-H1693 GDSC2 5.7916 7.4516 2.784 0.2832
NCI-H2135 GDSC2 5.8656 7.1943 2.8983 0.0897
NCI-H2405 GDSC2 5.896 8.1653 2.5642 0.8237
LXF 289 GDSC2 5.9043 8.3503 2.4969 1.0473
NCI-H1155 GDSC2 5.9613 7.4144 2.8574 0.1216
NCI-H441 GDSC2 6.0261 17.7041 -1.759 20.4041
NCI-H2228 GDSC2 6.028 9.4024 2.1309 2.4379
EBC-1 GDSC2 6.0561 8.5876 2.4709 1.0299
NCI-H2023 GDSC2 6.0867 7.6223 2.8309 0.1329
NCI-H661 GDSC2 6.1214 8.0094 2.71 0.3255
A-549 GDSC2 6.1238 14.6596 -0.2161 14.0143
NCI-H1437 GDSC2 6.197 8.2545 2.6513 0.4263
NCI-H1623 GDSC2 6.2944 8.1459 2.7256 0.2448
HCC15 GDSC2 6.3281 17.4077 -1.4002 18.4833
NCI-H520 GDSC2 6.4596 8.5789 2.6349 0.3671
⏷ Show the Full List of 166 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 3.383 6.1518 1.9576 8.4579
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OE19 GDSC2 3.6848 5.1709 2.6796 3.1252
OE33 GDSC2 3.8214 7.4881 1.6391 9.2566
TE-6 GDSC2 3.9387 6.1349 2.3904 4.3273
KYSE-270 GDSC2 4.2923 6.6874 2.3628 3.7623
KYSE-140 GDSC2 4.4077 9.9015 0.8873 12.2308
COLO 680N GDSC2 4.4092 6.6886 2.4353 3.1286
TE-15 GDSC2 4.4962 8.5121 1.6283 7.7103
TE-4 GDSC2 4.7836 7.9043 2.104 4.3498
TE-11 GDSC2 5.1088 9.1098 1.7469 5.7882
KYSE-520 GDSC2 5.2224 9.4143 1.6763 5.9792
KYSE-70 GDSC2 5.4189 8.0218 2.404 1.8692
TE-10 GDSC2 5.455 8.0362 2.4158 1.7768
TE-9 GDSC2 5.4977 7.0932 2.8007 0.3553
TE-8 GDSC2 5.6148 8.7241 2.2076 2.5612
KYSE-410 GDSC2 5.7181 11.7682 0.8898 9.3584
TE-5 GDSC2 5.8022 8.0085 2.5843 0.8182
KYSE-180 GDSC2 5.8371 7.7191 2.7058 0.4444
EC-GI-10 GDSC2 5.886 7.8145 2.6902 0.462
OE21 GDSC2 6.0072 7.9162 2.7002 0.3877
TE-1 GDSC2 6.0519 7.8491 2.7406 0.2866
KYSE-450 GDSC2 7.4276 19.9312 -1.8605 17.9951
KYSE-510 GDSC2 9.0628 24.3838 -2.895 18.47
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHOS-4 GDSC2 2.4319 5.6607 1.3477 15.3223
TOV-21G GDSC2 3.4715 6.8595 1.6762 9.9715
A2780 GDSC2 3.5599 6.358 1.9973 7.7157
OVCAR-4 GDSC2 3.9563 6.2484 2.3477 4.5497
ES-2 GDSC2 4.1031 6.3064 2.4198 3.7999
OVCAR-8 GDSC2 4.1288 6.1303 2.5197 3.1565
EFO-27 GDSC2 4.1338 9.0532 1.1016 11.6852
OVK18 GDSC2 4.202 6.405 2.4376 3.4975
SK-OV-3 GDSC2 4.2593 7.3962 2.0032 5.9788
OVCAR-3 GDSC2 4.2757 6.8181 2.2905 4.2213
OV56 GDSC2 4.3414 5.9563 2.726 1.6447
Caov-3 GDSC2 4.3429 7.0421 2.2284 4.4557
OVCAR-5 GDSC2 4.3467 11.3084 0.1473 16.3351
IGROV-1 GDSC2 4.3572 8.9216 1.331 9.7914
TOV-112D GDSC2 4.38 7.6947 1.9421 6.0866
OAW42 GDSC2 4.4278 7.5082 2.0631 5.2651
TYK-nu GDSC2 4.5242 7.8707 1.9546 5.7122
Kuramochi GDSC2 4.6882 10.8026 0.6501 12.8626
OVTOKO GDSC2 4.7894 12.0552 0.1098 15.4186
OVISE GDSC2 4.8764 6.4241 2.7959 0.7381
EFO-21 GDSC2 5.0914 13.3131 -0.2867 16.592
JHOS-2 GDSC2 5.5201 7.465 2.6722 0.7121
OAW28 GDSC2 5.5851 7.98 2.5001 1.292
DOV13 GDSC2 5.5937 7.0402 2.8553 0.2063
OV-90 GDSC2 6.4741 13.1095 0.739 8.7507
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaTu 8988t GDSC2 3.8527 16.8214 -2.9907 29.2065
HuP-T3 GDSC2 4.0033 6.5774 2.2212 5.2188
CFPAC-1 GDSC2 4.0451 5.9907 2.5314 3.2516
QGP-1 GDSC2 4.2693 9.8691 0.8005 13.0621
KP-2 GDSC2 4.3644 6.0853 2.6819 1.8425
HPAC GDSC2 4.3689 8.1641 1.7081 7.5164
PSN1 GDSC2 4.5335 6.8424 2.4395 2.8931
Panc 02.03 GDSC2 4.5438 9.3259 1.2672 9.73
SU.86.86 GDSC2 4.5682 6.4324 2.6414 1.7636
Panc 10.05 GDSC2 4.6537 8.3496 1.8126 6.2867
HuP-T4 GDSC2 4.7215 8.8837 1.6032 7.3757
KP-1N GDSC2 4.8707 7.2922 2.4305 2.4258
DAN-G GDSC2 5.0289 12.388 0.1207 14.7969
MIA PaCa-2 GDSC2 5.0357 6.7456 2.7407 0.8189
SUIT-2 GDSC2 5.0633 6.7468 2.7523 0.754
KP-4 GDSC2 5.1519 6.4363 2.9041 0.2509
PL4 GDSC2 5.3144 6.9845 2.7679 0.5353
YAPC GDSC2 5.5407 9.7998 1.692 5.3401
Capan-2 GDSC2 5.6395 12.2495 0.6104 10.9786
Panc 08.13 GDSC2 5.641 7.531 2.6972 0.5636
PaTu 8902 GDSC2 5.713 7.3792 2.7803 0.3183
Capan-1 GDSC2 5.7259 7.4028 2.7767 0.3214
KP-3 GDSC2 5.8049 8.0759 2.5598 0.8986
AsPC-1 GDSC2 6.0074 8.5633 2.4592 1.1059
BxPC-3 GDSC2 6.15 8.1453 2.6726 0.3959
HPAF-II GDSC2 6.1848 8.1583 2.681 0.3646
MZ-PC-1 GDSC2 6.5737 8.8728 2.5735 0.4592
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC2 3.7191 7.826 1.3918 11.0406
MPP 89 GDSC2 4.2023 6.4477 2.4177 3.614
MSTO-211H GDSC2 4.2421 7.0506 2.1575 5.0851
IST-Mes1 GDSC2 4.4531 11.529 0.1188 16.206
NCI-H2052 GDSC2 6.1141 8.2319 2.6276 0.5196
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC2 4.1131 7.0985 2.0455 6.0462
NCI-H660 GDSC2 4.771 6.1692 2.849 0.6236
LNCaP clone FGC GDSC2 4.8812 7.7582 2.2291 3.4853
PC-3 GDSC2 5.1233 7.879 2.3117 2.684
22Rv1 GDSC2 5.966 8.2764 2.5514 0.8208
DU145 GDSC2 5.9946 7.896 2.7026 0.3871
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 5.632 7.586 2.673 0.6408
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IPC-298 GDSC2 2.8968 10.1806 -0.4678 23.439
Hs 940.T GDSC2 3.5577 6.0401 2.154 6.736
DJM-1 GDSC2 3.6571 9.619 0.4481 16.6394
A2058 GDSC2 3.6952 6.7466 1.9099 7.904
G-mel GDSC2 3.7679 6.1466 2.2618 5.5211
G-361 GDSC2 3.7811 6.4195 2.1372 6.2653
MZ-MEL-7 GDSC2 3.7937 5.4865 2.6031 3.3486
SK-MEL-30 GDSC2 3.8156 6.4234 2.1609 6.0327
A101D GDSC2 3.887 6.1969 2.3239 4.853
A-431 GDSC2 3.9808 7.1117 1.9442 6.9761
WM1552C GDSC2 4.0265 10.6779 0.2134 16.8443
GAK GDSC2 4.1131 7.1067 2.0415 6.0706
COLO 800 GDSC2 4.1642 7.4198 1.9254 6.6628
SK-MEL-31 GDSC2 4.1911 10.9846 0.1886 16.5315
Hs 938.T GDSC2 4.2131 6.6328 2.3373 4.0689
LOX-IMVI GDSC2 4.2628 7.8393 1.7912 7.2542
A-375 GDSC2 4.2806 8.7908 1.3394 9.9242
IGR-37 GDSC2 4.4019 8.7582 1.4428 9.0257
SK-MEL-2 GDSC2 4.4469 6.4651 2.5593 2.3747
HMV-II GDSC2 4.4495 10.9092 0.4221 14.6609
COLO 679 GDSC2 4.4621 7.7627 1.9648 5.7789
SK-MEL-3 GDSC2 4.4671 7.5544 2.0671 5.1621
WM35 GDSC2 4.4782 8.8302 1.4618 8.7384
WT2-iPS GDSC2 4.4986 7.6337 2.0501 5.1991
CP50-MEL-B GDSC2 4.5219 10.0658 0.8903 11.9371
WM793 GDSC2 4.541 6.3278 2.6721 1.6452
SK-MEL-24 GDSC2 4.5654 9.0307 1.4257 8.7544
CP66-MEL GDSC2 4.5893 6.1829 2.7586 1.1689
Mel Ho GDSC2 4.5911 9.4433 1.2436 9.7589
COLO 792 GDSC2 4.5944 7.4659 2.19 4.1993
SK-MEL-5 GDSC2 4.6023 7.975 1.9564 5.545
COLO 783 GDSC2 4.8693 6.3365 2.8269 0.6299
451Lu GDSC2 4.8852 10.5068 0.9342 10.8502
WM115 GDSC2 4.9731 6.889 2.6543 1.2268
LB373-MEL-D GDSC2 5.0188 6.1832 2.9439 0.2121
RPMI-7951 GDSC2 5.0197 7.1918 2.5517 1.638
SH-4 GDSC2 5.0907 7.2701 2.5544 1.5462
WM278 GDSC2 5.1463 10.2553 1.2324 8.6248
MMAc-SF GDSC2 5.2152 10.561 1.1326 9.0411
LB2518-MEL GDSC2 5.2674 6.6876 2.8582 0.3121
IGR-1 GDSC2 5.2831 7.0386 2.7345 0.6606
MZ-MEL-2 GDSC2 5.3578 14.5094 -0.6792 17.7122
A-388 GDSC2 5.3975 8.343 2.2573 2.5919
VMRC-MELG GDSC2 5.4156 6.9215 2.8309 0.3168
UACC-62 GDSC2 5.4282 6.7636 2.8912 0.1877
SK-MEL-28 GDSC2 5.4824 15.2666 -0.9596 18.5936
Mel JuSo GDSC2 5.4889 6.9218 2.8583 0.2317
UACC-257 GDSC2 5.5743 7.5314 2.6697 0.6859
RVH-421 GDSC2 5.6721 7.4752 2.73 0.4569
CHL-1 GDSC2 5.8508 7.3835 2.8292 0.1841
M14 GDSC2 5.9588 7.5508 2.8103 0.1885
COLO 829 GDSC2 6.0678 7.8121 2.7593 0.2467
HT-144 GDSC2 7.0031 17.2964 -0.8869 15.1673
EquiPSC Line K2 GDSC2 4.7997 7.9374 2.0986 4.352
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 3.8529 7.1918 1.8097 8.1225
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-401 GDSC2 2.7453 7.9447 0.514 19.0839
TE 441.T GDSC2 3.5628 5.2844 2.5334 4.3344
Rh41 GDSC2 3.5671 7.3342 1.5163 10.6949
KYM-1 GDSC2 3.7487 7.2364 1.708 9.0201
STS-0421 GDSC2 3.8095 6.1177 2.3066 5.142
G-402 GDSC2 3.9413 7.4124 1.7672 8.1638
SK-LMS-1 GDSC2 4.1686 8.1238 1.5849 8.723
SW872 GDSC2 4.3185 9.3882 1.0739 11.3856
GCT GDSC2 4.3531 8.2405 1.66 7.8402
VA-ES-BJ GDSC2 4.3792 8.0987 1.7469 7.26
RD GDSC2 4.6296 8.3268 1.8075 6.366
SK-UT-1 GDSC2 4.7408 8.2089 1.9355 5.3968
HT-1080 GDSC2 4.768 7.719 2.1797 3.9491
SW982 GDSC2 4.8058 12.7663 -0.2279 17.0019
SW684 GDSC2 5.1757 6.6318 2.8427 0.3936
MES-SA GDSC2 5.3164 6.8615 2.8142 0.4022
A-204 GDSC2 5.4116 10.1035 1.474 6.7617
Rh30 GDSC2 5.6199 7.2272 2.7992 0.3106
EW-8 GDSC2 5.6688 7.2909 2.795 0.3022
RKN GDSC2 5.6782 6.9319 2.9218 0.0914
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AGS GDSC2 3.298 10.9475 -0.5108 22.382
MKN45 GDSC2 3.3786 7.1114 1.4742 11.4885
SNU-5 GDSC2 3.6673 13.0617 -1.2632 24.3569
MKN7 GDSC2 3.6728 11.5065 -0.4817 21.1531
MKN1 GDSC2 3.8823 8.3027 1.2818 11.2694
RF-48 GDSC2 4.214 7.6051 1.8706 6.8834
NUGC-3 GDSC2 4.2284 6.1148 2.5892 2.5721
ECC12 GDSC2 4.3179 8.8143 1.355 9.7428
SCH GDSC2 4.3732 10.152 0.7385 13.1455
23132/87 GDSC2 4.4147 9.4309 1.1234 10.8671
ECC10 GDSC2 4.4734 8.3661 1.683 7.4348
MKN28 GDSC2 4.5039 8.9996 1.3976 9.0586
KATO III GDSC2 4.5578 7.049 2.3599 3.2971
NCI-N87 GDSC2 4.9392 9.0952 1.6462 6.6849
OCUM-1 GDSC2 4.9912 12.0718 0.2481 14.2494
IM95 GDSC2 5.2255 8.9769 1.8793 4.8431
Hs 746.T GDSC2 5.3498 7.8103 2.4577 1.7015
TMK-1 GDSC2 5.4619 7.453 2.6521 0.8193
NUGC-4 GDSC2 5.4709 7.2343 2.7385 0.5353
HGC-27 GDSC2 5.5873 8.204 2.4107 1.662
GCIY GDSC2 5.6245 8.4539 2.326 1.9976
SK-GT-2 GDSC2 5.6499 7.8682 2.5731 0.9625
SNU-1 GDSC2 5.7451 7.4053 2.7831 0.3009
RERF-GC-1B GDSC2 6.5273 9.1024 2.4722 0.7393
SNG-M GDSC2 5.4408 9.7622 1.6495 5.7415
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC2 3.8925 6.7181 2.0727 6.3935
8505C GDSC2 3.9088 8.8332 1.0388 12.6346
8305C GDSC2 3.9121 6.7594 2.0668 6.3827
K5 GDSC2 4.1385 7.4544 1.8904 6.9354
HTC-C3 GDSC2 4.3907 8.3722 1.6226 7.9796
B-CPAP GDSC2 4.5797 11.3153 0.3189 14.8742
FTC-133 GDSC2 4.5927 7.7932 2.0359 5.0978
WRO GDSC2 4.7608 10.4898 0.8548 11.573
CAL-62 GDSC2 5.1185 6.4963 2.8697 0.3487
ML-1 [Human leukemia] GDSC2 5.3239 14.9469 -0.9183 18.7864
IHH-4 GDSC2 5.3869 6.9961 2.7928 0.4256
ASH-3 GDSC2 5.5722 7.3642 2.7312 0.5027
TT2609-C02 GDSC2 5.7247 8.8454 2.2123 2.4075
BHT-101 GDSC2 6.37 16.0977 -0.7389 15.7929
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KON GDSC2 3.8428 6.292 2.2454 5.4417
PCI-15A GDSC2 3.8697 7.6841 1.5788 9.5018
OSC-20 GDSC2 3.9871 7.5219 1.7472 8.1734
FaDu GDSC2 4.1279 5.7104 2.7138 2.0425
PCI-04B GDSC2 4.1944 6.4194 2.4259 3.581
KOSC-2 GDSC2 4.2941 8.442 1.5199 8.8167
CAL-27 GDSC2 4.3262 5.9617 2.7152 1.7232
PE/CA-PJ15 GDSC2 4.3591 7.6637 1.9428 6.1274
BB49-HNC GDSC2 4.388 10.339 0.6574 13.5541
HSC-2 GDSC2 4.4174 5.7732 2.844 0.9692
PCI-06A GDSC2 4.4763 7.9845 1.8683 6.3238
Detroit 562 GDSC2 4.5802 6.7159 2.5234 2.3622
JHU-029 GDSC2 4.6084 7.3556 2.2497 3.8326
HO-1-N-1 GDSC2 4.7799 6.9223 2.5425 1.9793
SAS GDSC2 4.8212 9.7889 1.2365 9.2867
JHU-022 GDSC2 4.8831 9.728 1.308 8.7443
NCI-H3118 GDSC2 4.8934 7.3136 2.4335 2.3785
DOK GDSC2 4.9066 7.7869 2.2309 3.4344
BB30-HNC GDSC2 4.9302 17.2369 -2.3449 24.7643
SKN-3 GDSC2 4.9559 8.3547 2.0018 4.6237
JHU-011 GDSC2 5.0525 12.7432 -0.0359 15.5044
Ca9-22 GDSC2 5.0845 7.1432 2.6037 1.3337
HSC-3 GDSC2 5.1066 6.5839 2.8326 0.4587
SCC-15 GDSC2 5.2723 6.9824 2.7513 0.6127
LB771-HNC GDSC2 5.2732 11.7809 0.5874 11.8682
SCC-9 GDSC2 5.4156 7.3098 2.6872 0.7311
SCC-25 GDSC2 5.4415 7.4958 2.6266 0.925
SCC-4 GDSC2 5.4432 8.296 2.3011 2.3219
SAT [Human HNSCC] GDSC2 5.4671 8.976 2.0191 3.7082
OSC-19 GDSC2 5.4745 7.4141 2.6724 0.7413
BICR 22 GDSC2 5.5381 7.0627 2.8269 0.28
BICR 78 GDSC2 5.6685 8.332 2.3972 1.6394
CAL-33 GDSC2 5.6782 7.7721 2.622 0.7745
BICR 10 GDSC2 5.7431 7.5687 2.7238 0.4405
UPCI-SCC-090 GDSC2 5.7859 7.8163 2.6498 0.6231
HSC-4 GDSC2 5.8473 7.2337 2.8788 0.1146
BHY GDSC2 5.8873 7.9051 2.6577 0.5474
BICR 31 GDSC2 6.0917 7.9663 2.7141 0.3268
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC2 3.8748 9.4561 0.7026 14.6428
BFTC-905 GDSC2 4.0276 6.2005 2.4198 3.9561
SW780 GDSC2 4.1365 7.6163 1.8099 7.4314
RT-112 GDSC2 4.2531 5.914 2.695 1.9419
647V GDSC2 4.372 8.2395 1.6738 7.7153
SW1710 GDSC2 4.4567 7.0997 2.2742 3.9681
639V GDSC2 4.5582 5.7637 2.9136 0.5499
TCCSUP GDSC2 4.7708 7.705 2.1878 3.8986
HT-1197 GDSC2 4.8474 10.1577 1.0767 10.1369
RT-4 GDSC2 5.2967 12.5049 0.2539 13.5262
J82 GDSC2 5.3771 8.8492 2.0248 3.8123
CAL-29 GDSC2 5.5182 7.0839 2.8118 0.3207
T24 GDSC2 5.5788 9.1084 2.0226 3.5295
5637 GDSC2 5.9951 7.6087 2.8033 0.191
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PA-1 GDSC2 2.212 5.7066 1.1133 17.5237
OV17R GDSC2 2.9781 6.4923 1.4418 12.9039
OVMIU GDSC2 3.6853 7.6648 1.4454 10.8057
C-33 A GDSC2 3.7413 5.9458 2.341 5.0926
HeLa GDSC2 3.7509 6.5292 2.0603 6.8212
NEC8 GDSC2 3.9839 7.5499 1.7311 8.2802
JHOS-3 GDSC2 4.1318 7.2131 2.003 6.2634
SiHa GDSC2 4.3322 6.7566 2.3558 3.7273
DSH1 GDSC2 4.3419 8.6833 1.4364 9.2028
SW756 GDSC2 4.3688 7.8481 1.8607 6.5992
JEG-3 GDSC2 4.3873 8.6856 1.4677 8.9111
HEC-1 GDSC2 4.5129 7.1721 2.2757 3.8555
DoTc2 4510 GDSC2 4.5397 9.2709 1.2911 9.6003
SKN GDSC2 4.5854 6.8997 2.4441 2.7835
ACC-OV7 GDSC2 4.6872 8.2911 1.8622 5.9285
MS751 GDSC2 4.8208 6.9783 2.54 1.9377
SKG-IIIa GDSC2 4.8955 8.9224 1.6994 6.4638
TC-YIK GDSC2 4.9725 7.5822 2.3592 2.6509
SW954 GDSC2 5.003 6.8957 2.6657 1.1483
UWB1.289 GDSC2 5.1054 7.8237 2.3261 2.6348
C-4-I GDSC2 5.1806 6.9107 2.7399 0.7125
LB831-BLC GDSC2 5.3064 12.233 0.3922 12.8058
PWR-1E GDSC2 5.3126 8.2613 2.2475 2.7521
ME-180 GDSC2 5.3453 10.044 1.4603 6.9607
JAR GDSC2 5.3789 7.7879 2.481 1.568
HEY GDSC2 5.4373 7.8909 2.467 1.5698
HT-3 GDSC2 5.5127 7.4216 2.6855 0.6737
OVCA420 GDSC2 5.5393 7.8163 2.5444 1.157
PEO1 GDSC2 5.6192 7.6929 2.6273 0.7958
SiSo GDSC2 5.6982 9.0524 2.1108 2.9262
OMC-1 [Human cervical carcinoma] GDSC2 5.8095 7.7821 2.6719 0.5472
SW962 GDSC2 5.8323 7.703 2.7097 0.4366
BPH-1 GDSC2 5.8881 9.2568 2.1218 2.6401
Ca Ski GDSC2 5.9309 8.3191 2.5203 0.9468
OVCA433 GDSC2 6.1714 8.1234 2.6884 0.3536
CAL-39 GDSC2 6.235 8.5069 2.5748 0.6023
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2619).