Details of the Drug

General Information of Drug (ID: DMIRCF1)

Drug Name
QR1123
Synonyms ION357
Indication
Disease Entry ICD 11 Status REF
Retinitis pigmentosa 9B70 Phase 1/2 [1]
Drug Type
Antisense oligonucleotide
Cross-matching ID
DrugBank ID
DB17869
TTD ID
DX71CK

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Rhodopsin P23H mutant messenger RNA (RHO P23H mRNA) TTG6VJM OPSD_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04123626) A Prospective First-In-Human Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa (adRP) Due to the P23H Mutation in the RHO Gene. U.S.National Institutes of Health.