Details of the Drug

General Information of Drug (ID: DMIXY1O)

Drug Name
HC067047
Synonyms HC 067047
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 471.5
Logarithm of the Partition Coefficient (xlogp) 4.4
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C26H28F3N3O2
IUPAC Name
2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
Canonical SMILES
CC1=C(C=C(N1CCCN2CCOCC2)C3=CC=CC=C3)C(=O)NC4=CC=CC(=C4)C(F)(F)F
InChI
InChI=1S/C26H28F3N3O2/c1-19-23(25(33)30-22-10-5-9-21(17-22)26(27,28)29)18-24(20-7-3-2-4-8-20)32(19)12-6-11-31-13-15-34-16-14-31/h2-5,7-10,17-18H,6,11-16H2,1H3,(H,30,33)
InChIKey
NCZYSQOTAYFTNM-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
2742550
CAS Number
883031-03-6
TTD ID
D0B1QM

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Transient receptor potential cation channel V4 (TRPV4) TTKP2SU TRPV4_HUMAN Blocker (channel blocker) [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 143 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 4.6173 6.8323 4.2184 10.9669
JK1 CTRP2 8.816 21.2494 0.6098 16.4243
JM1 CTRP2 5.3772 10.87 3.0553 13.8609
HuT 78 CTRP2 1.1324 10.5828 -0.9909 38.0458
EoL-1 CTRP2 2.4833 4.3444 2.4583 23.8084
HH [Human lymphoma] CTRP2 2.8329 6.7861 2.3123 23.2376
GA-10 CTRP2 2.9484 5.9107 2.7012 21.4857
697 CTRP2 2.9771 4.6743 2.9485 20.5312
Pfeiffer CTRP2 3.0258 5.5762 2.8651 20.6637
KMS-20 CTRP2 3.4004 5.2769 3.3264 17.8665
AML-193 CTRP2 3.4076 4.4275 3.4044 17.5774
K-562 CTRP2 3.4599 5.0655 3.4186 17.358
DND-41 CTRP2 3.4876 6.2156 3.2055 18.0264
KMS-34 CTRP2 3.6637 5.7741 3.5148 16.3755
Mino CTRP2 3.7476 7.3998 3.0712 17.7771
SEM CTRP2 3.7721 5.5424 3.6814 15.4492
MOLT-16 CTRP2 3.8354 6.0291 3.6378 15.4071
Daudi CTRP2 3.9708 6.0349 3.784 14.4675
LP-1 CTRP2 4.0675 8.1336 3.0996 16.8006
L-428 CTRP2 4.1034 5.5763 4.0331 13.1716
KMS-21-BM CTRP2 4.1068 7.6047 3.3664 15.6562
L-540 CTRP2 4.1643 5.2658 4.1413 12.6031
ST486 CTRP2 4.2023 7.6753 3.4362 15.1278
NCO2 CTRP2 4.2332 8.0573 3.303 15.5682
KMS-11 CTRP2 4.2532 6.8526 3.8218 13.5004
MOTN-1 CTRP2 4.2703 9.943 2.4731 18.7257
TALL-1 [Human adult T-ALL] CTRP2 4.2939 6.1057 4.117 12.2828
EB1 CTRP2 4.3099 6.8333 3.8898 13.0821
CML-T1 CTRP2 4.321 5.2536 4.3066 11.53
JVM-3 CTRP2 4.3299 6.0127 4.1819 11.9391
M-07e CTRP2 4.3313 7.2723 3.7394 13.6001
OPM-2 CTRP2 4.3364 6.847 3.913 12.919
DB CTRP2 4.3392 6.5163 4.0362 12.4464
KMS-12-BM CTRP2 4.4268 5.3317 4.4109 10.8304
WSU-DLCL2 CTRP2 4.4566 4.9603 4.4562 10.5795
NU-DUL-1 CTRP2 4.4813 5.9388 4.3662 10.8134
KE-37 CTRP2 4.5106 5.3942 4.4932 10.2769
JJN-3 CTRP2 4.522 9.2367 3.0522 15.8345
SUP-T11 CTRP2 4.5366 5.3004 4.5276 10.0753
Granta-519 CTRP2 4.546 8.3901 3.4703 14.1027
MOLM-13 CTRP2 4.5489 6.0858 4.4009 10.4824
OCI-M1 CTRP2 4.5733 6.3814 4.3357 10.649
NU-DHL-1 CTRP2 4.6067 5.7062 4.5531 9.7618
KHM-1B CTRP2 4.607 5.867 4.5203 9.8758
ALL-SIL CTRP2 4.656 6.3311 4.4422 10.0116
P12-Ichikawa CTRP2 4.6777 6.5688 4.3827 10.1717
BL-70 CTRP2 4.7192 5.6626 4.6817 8.9564
EM-2 CTRP2 4.746 5.6034 4.719 8.7416
Kasumi-2 CTRP2 4.7483 6.39 4.5225 9.4436
Mono-Mac-1 CTRP2 4.755 6.6955 4.418 9.819
THP-1 CTRP2 4.7934 5.8465 4.7277 8.5608
F-36P CTRP2 4.8475 6.9366 4.4199 9.557
BV-173 CTRP2 4.8577 7.2789 4.2851 10.0583
JURL-MK1 CTRP2 4.8621 6.8779 4.4593 9.3645
DoHH2 CTRP2 4.8691 13.8835 1.107 22.2174
Peer CTRP2 4.8911 8.9999 3.5221 13.0525
RL CTRP2 4.8934 6.9744 4.4523 9.3069
DEL CTRP2 4.9607 5.8659 4.9053 7.4104
Ci-1 CTRP2 4.9707 6.3092 4.791 7.7956
U-937 CTRP2 4.9736 6.1008 4.8599 7.5335
OCI-AML-3 CTRP2 4.9947 8.5357 3.8436 11.4966
MOLT-3 CTRP2 5.0259 5.8638 4.9765 6.9553
KMS-18 CTRP2 5.0864 6.5477 4.8285 7.3241
HD-MY-Z CTRP2 5.1221 6.5761 4.8554 7.1217
KO52 CTRP2 5.1649 9.2517 3.6595 11.856
RCH-ACV CTRP2 5.1908 9.215 3.7016 11.624
SET-2 CTRP2 5.1978 6.0349 5.1231 5.9011
HPB-ALL CTRP2 5.2176 6.8293 4.8512 6.8793
CA46 CTRP2 5.2189 11.0164 2.8409 15.0671
A3/Kawakami CTRP2 5.2257 5.9507 5.1747 5.6307
Namalwa CTRP2 5.2772 9.0574 3.8589 10.7803
SUP-M2 CTRP2 5.2822 6.0539 5.21 5.3308
Hs 611.T CTRP2 5.3145 9.2358 3.8059 10.9156
REC-1 CTRP2 5.3155 10.4627 3.2018 13.3987
NALM-6 CTRP2 5.4001 8.3876 4.3004 8.6764
RS4;11 CTRP2 5.4134 7.8684 4.5649 7.5545
OCI-Ly3 CTRP2 5.4496 7.3312 4.8567 6.2729
SK-MM-2 CTRP2 5.4692 10.2872 3.4264 12.1471
SIG-M5 CTRP2 5.5524 6.1577 5.4728 3.5619
Ri-1 CTRP2 5.626 8.9311 4.2391 8.4358
MOLM-6 CTRP2 5.6696 9.7654 3.863 9.9142
EJM CTRP2 5.6881 11.9748 2.7772 14.3231
KYO-1 CTRP2 5.7361 7.3493 5.1201 4.5241
MOLP-8 CTRP2 5.7575 6.5098 5.544 2.7316
TF-1 CTRP2 5.8909 9.7994 4.0375 8.7339
Mono-Mac-6 CTRP2 5.9547 13.7147 2.1342 16.268
KE-97 CTRP2 6.0554 7.3669 5.3923 2.7196
MOLP-2 CTRP2 6.0658 9.3922 4.3883 6.9193
Ku812 CTRP2 6.0729 9.4097 4.3854 6.9179
U266B1 CTRP2 6.0746 8.744 4.7197 5.5102
Toledo CTRP2 6.0835 7.725 5.2365 3.3211
MOLM-16 CTRP2 6.2189 8.7746 4.8219 4.8116
RPMI-8402 CTRP2 6.2919 10.0283 4.2547 7.057
JeKo-1 CTRP2 6.4726 12.1956 3.3179 10.614
SR CTRP2 6.5216 9.2049 4.8421 4.2041
SU-DHL-4 CTRP2 6.5831 11.1811 3.9101 7.9756
SUP-T1 CTRP2 6.7091 10.6684 4.2603 6.3082
OCI-AML-2 CTRP2 6.7764 10.1279 4.5759 4.8946
OCI-Ly19 CTRP2 6.8556 16.2636 1.5941 16.4981
PL21 CTRP2 6.9222 10.9387 4.2846 5.8631
EHEB CTRP2 6.9342 10.0385 4.7315 4.0194
MHH-CALL-4 CTRP2 6.9399 11.064 4.2362 6.0341
MHH-CALL-3 CTRP2 6.9633 11.1779 4.1974 6.1564
Karpas-299 CTRP2 6.9985 11.0242 4.2979 5.6896
Raji CTRP2 7.0145 9.9722 4.8183 3.5546
Ki-JK CTRP2 7.0169 12.8409 3.4187 9.2536
SU-DHL-1 CTRP2 7.0367 11.4669 4.109 6.4035
HEL 92.1.7 CTRP2 7.0524 10.6575 4.5143 4.7264
MOLT-13 CTRP2 7.0885 11.2638 4.2453 5.7665
CMK CTRP2 7.1487 8.8573 5.4167 1.1214
P31/FUJ CTRP2 7.1576 10.6492 4.5907 4.2659
MM1.S CTRP2 7.1611 12.4511 3.7173 7.8059
Karpas-620 CTRP2 7.1981 8.7634 5.4834 0.8573
HEL CTRP2 7.2597 9.8649 5.0269 2.422
NOMO-1 CTRP2 7.2773 9.1065 5.3777 1.1366
HL-60 CTRP2 7.3214 9.078 5.4132 0.9819
OCI-AML-5 CTRP2 7.3289 11.1443 4.4692 4.5127
MC116 CTRP2 7.3306 8.1268 5.7881 0.0684
Reh CTRP2 7.339 10.7761 4.6509 3.7788
Kasumi-1 CTRP2 7.4149 10.654 4.7571 3.2671
SU-DHL-10 CTRP2 7.4558 8.3197 5.7665 0.0713
ME1 CTRP2 7.4614 11.0939 4.5803 3.8956
HuNS1 CTRP2 7.469 10.3192 4.9452 2.4869
NB4 CTRP2 7.4733 11.9151 4.1976 5.3955
AMO1 CTRP2 7.5603 8.7775 5.6427 0.2317
SUP-HD1 CTRP2 7.5719 12.0638 4.1928 5.2772
HT CTRP2 7.5978 12.7705 3.8714 6.5215
LAMA-84 CTRP2 7.6423 17.1549 1.7581 14.5424
SKM-1 CTRP2 7.6473 10.1275 5.1332 1.628
Karpas-422 CTRP2 7.6548 9.6644 5.335 0.9667
SUP-B15 CTRP2 7.6817 12.489 4.0632 5.6398
L-363 CTRP2 7.7154 9.8991 5.2671 1.1301
P3HR-1 CTRP2 7.8219 15.8295 2.5426 11.3817
RPMI-8226 CTRP2 7.8262 13.5795 3.6385 7.1186
OCI-Ly10 CTRP2 7.8846 17.0413 1.994 13.303
RPMI-6666 CTRP2 7.9053 10.2154 5.2297 1.1018
JVM-2 CTRP2 7.9493 10.2928 5.2193 1.1012
Jurkat CTRP2 7.9798 15.3866 2.8715 9.8857
SU-DHL-8 CTRP2 8.2175 16.2263 2.6311 10.4397
GDM-1 CTRP2 8.3075 11.1173 5.0534 1.3405
KM-H2 CTRP2 8.5809 15.7912 3.0883 8.1941
KCL-22 CTRP2 8.6177 17.9812 2.0607 11.9272
KMM-1 CTRP2 8.6463 11.4491 5.0798 1.0391
⏷ Show the Full List of 143 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 5.4628 11.1278 3.0031 13.8889
TE8 CTRP2 5.7288 9.5856 4.0044 9.2016
KYSE-410 CTRP2 4.5466 6.558 4.2455 11.0634
TE-6 CTRP2 5.1862 7.9832 3.6914 5.8058
KYSE-30 CTRP2 5.2702 6.0926 5.1858 5.4549
TE-5 CTRP2 5.379 6.8899 4.9903 5.9082
OE21 CTRP2 5.395 12.5897 2.216 17.1212
TE-4 CTRP2 5.4523 9.6632 3.7206 10.9673
TE-14 CTRP2 5.6251 9.5452 3.9333 9.7143
KYSE-510 CTRP2 6.225 7.4564 5.4826 2.0348
KYSE-150 CTRP2 6.9885 9.0167 5.2519 1.8891
COLO 680N CTRP2 7.3441 11.3761 4.3685 4.8939
KYSE-180 CTRP2 7.3617 11.619 4.2639 5.2883
EC-GI-10 CTRP2 7.4288 13.5619 3.3677 8.792
KYSE-520 CTRP2 7.6427 10.5437 4.9458 2.2944
KYSE-450 CTRP2 7.6742 13.1716 3.7307 6.9719
KYSE-70 CTRP2 7.7445 10.7749 4.9007 2.3506
TE-11 CTRP2 7.8736 15.7801 2.604 11.0681
OE19 CTRP2 7.9078 11.5415 4.6497 3.0926
TE-1 CTRP2 7.955 14.0351 3.5074 7.4505
KYSE-140 CTRP2 8.4709 16.0216 2.9044 9.0416
OE33 CTRP2 8.5971 15.4402 3.2655 7.5009
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.8009 13.345 3.7338 6.7776
Panc 08.13 CTRP2 5.0139 8.057 4.0887 10.4521
MIA PaCa-2 CTRP2 5.3157 8.7 4.0693 9.8236
SW1990 CTRP2 5.3542 24.9047 -3.9669 32.6241
Panc 03.27 CTRP2 5.4101 6.9864 4.9781 5.8785
HuP-T3 CTRP2 5.6817 12.8688 2.3254 16.1006
PaTu 8988s CTRP2 5.7898 8.4084 4.6441 6.3965
Capan-1 CTRP2 5.8151 7.9876 4.8757 5.3739
DAN-G CTRP2 5.8297 7.4225 5.1691 4.1157
SNU-410 CTRP2 5.8677 8.2978 4.7673 5.719
PSN1 CTRP2 5.8739 9.4014 4.2218 7.9954
HuP-T4 CTRP2 5.9789 11.9799 3.0219 12.7552
PaTu 8902 CTRP2 6.0607 7.6968 5.2318 3.3843
KP-4 CTRP2 6.1196 9.4873 4.3852 6.8296
Hs 766T CTRP2 6.167 10.2086 4.0636 8.0893
BxPC-3 CTRP2 6.1751 13.3947 2.4775 14.5253
Panc 04.03 CTRP2 6.1773 7.9794 5.1853 3.3628
SU.86.86 CTRP2 6.2511 13.5297 2.4726 14.3973
Capan-2 CTRP2 6.6828 8.7114 5.1981 2.4974
HPAF-II CTRP2 6.6935 13.9217 2.6327 12.9487
TCC-Pan2 CTRP2 7.3883 13.2274 3.5019 8.3179
AsPC-1 CTRP2 7.4736 19.9729 0.2324 19.7567
PaTu 8988t CTRP2 7.5046 11.7518 4.2967 4.9571
HPAC CTRP2 7.6894 13.2431 3.7067 7.0453
Panc 02.03 CTRP2 7.742 9.3427 5.5049 0.4504
YAPC CTRP2 7.7474 8.9007 5.6704 0.1338
KP-3 CTRP2 7.8259 14.4801 3.2032 8.8322
PK-45H CTRP2 7.849 13.7025 3.5949 7.2579
SNU-213 CTRP2 7.8918 13.1469 3.8896 6.037
QGP-1 CTRP2 7.9213 11.2766 4.7775 2.6105
SUIT-2 CTRP2 8.026 9.3203 5.626 0.1335
KP-2 CTRP2 8.0364 13.4143 3.858 5.966
CFPAC-1 CTRP2 8.2754 14.2906 3.5995 6.6507
L3.3 CTRP2 8.3695 13.7842 3.898 5.3832
Panc 05.04 CTRP2 9.1825 15.6784 3.5235 5.8094
PK-59 CTRP2 9.6528 19.4036 2.0796 10.4098
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 4.1738 11.8327 1.4743 22.6239
COLO 792 CTRP2 4.777 7.2782 4.2021 10.5978
SK-MEL-5 CTRP2 4.7975 5.7212 4.7563 8.4474
RPMI-7951 CTRP2 4.8858 6.0457 4.7797 8.0899
Hs 940.T CTRP2 4.9721 9.3247 3.4429 13.1859
SK-MEL-24 CTRP2 5.3263 9.7315 3.5728 11.8526
Hs 895.T CTRP2 5.392 10.8572 3.0748 13.7496
Hs 294T CTRP2 5.3949 8.1247 4.4233 8.1805
MeWo CTRP2 5.3965 7.8395 4.5627 7.6029
WM115 CTRP2 5.4459 6.2742 5.3167 4.4545
UACC-62 CTRP2 5.4855 6.0798 5.4244 3.9384
CJM [Human melanoma] CTRP2 5.516 14.0407 1.5978 19.1248
RVH-421 CTRP2 5.563 8.9565 4.17 8.859
HT-144 CTRP2 5.569 10.1302 3.593 11.2474
IGR-1 CTRP2 5.5723 7.4793 4.9036 5.7917
WM266-4 CTRP2 5.7485 6.663 5.4637 3.0792
IGR-37 CTRP2 5.7852 19.8374 -1.0693 26.3596
UACC-257 CTRP2 5.8004 6.8039 5.4461 3.029
WM88 CTRP2 5.932 8.3593 4.792 5.4852
SK-MEL-2 CTRP2 5.984 6.6646 5.6826 1.6415
WM983B CTRP2 6.0263 7.6029 5.25 3.374
COLO 829 CTRP2 6.1337 7.5514 5.364 2.6921
WT2-iPS CTRP2 6.2123 7.3273 5.5369 1.83
IPC-298 CTRP2 6.6041 8.6651 5.1662 2.7409
Hs 934.T CTRP2 6.8438 9.9683 4.7021 4.2732
Hs 839.T CTRP2 6.8596 12.6463 3.3958 9.6124
A2058 CTRP2 6.9519 9.3111 5.0913 2.556
SK-MEL-28 CTRP2 7.0094 7.7561 5.799 0.1286
Hs 688(A).T CTRP2 7.0114 9.9028 4.8494 3.4346
SK-MEL-30 CTRP2 7.0309 9.9889 4.8214 3.5195
HMCB CTRP2 7.0468 10.2034 4.7293 3.8661
IGR-39 CTRP2 7.1584 12.5647 3.6597 8.0444
Hs 944.T CTRP2 7.2623 11.1933 4.4006 4.881
G-361 CTRP2 7.3565 11.9682 4.0918 5.9882
SK-MEL-3 CTRP2 7.4676 12.7689 3.7817 7.0722
WM793 CTRP2 7.5331 10.3738 4.9585 2.366
SK-MEL-31 CTRP2 7.554 12.8703 3.7929 6.8992
WM1799 CTRP2 7.6531 9.2451 5.5039 0.4976
Hs 936.T CTRP2 7.7748 8.8782 5.6884 0.105
A101D CTRP2 7.9631 11.261 4.8083 2.4567
A-375 CTRP2 7.9716 9.8616 5.4035 0.5796
Hs 852.T CTRP2 8.0595 9.6205 5.5314 0.2697
MDA-MB-435S CTRP2 8.1153 12.7545 4.218 4.4754
Mel Ho CTRP2 8.2195 14.3903 3.5153 7.0516
Mel JuSo CTRP2 8.2504 12.7608 4.298 4.014
COLO 800 CTRP2 8.3881 12.4442 4.5222 3.0438
LOX-IMVI CTRP2 8.4637 15.665 3.0703 8.4237
K029AX CTRP2 10.6212 26.8268 -0.824 17.8055
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 5.1221 8.2564 4.0997 10.1474
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-BE(2) CTRP2 4.2353 7.4205 3.5776 14.4886
SiMa CTRP2 4.4176 6.4418 4.1466 11.8068
CHP-212 CTRP2 5.0446 7.6482 4.3091 9.4847
SK-N-AS CTRP2 5.5302 6.3586 5.3746 3.9971
SK-N-DZ CTRP2 5.6683 6.2553 5.5619 2.895
IMR-32 CTRP2 5.8877 10.6484 3.6105 10.5216
MHH-NB-11 CTRP2 5.9286 7.2658 5.3347 3.2145
KP-N-YN CTRP2 6.3183 13.5172 2.5337 14.0319
CHP-126 CTRP2 6.9907 11.7241 3.9493 7.1309
SK-N-SH CTRP2 7.2676 11.944 4.0414 6.3243
SK-N-FI CTRP2 7.7781 12.4641 4.1389 5.2105
NB1 CTRP2 7.8302 9.3946 5.5225 0.3713
NH-6 CTRP2 8.1007 11.9992 4.556 3.2255
Kelly CTRP2 8.2513 9.7699 5.5513 0.1852
KP-N-SI9s CTRP2 8.6082 13.5285 4.1615 4.1165
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 3.7896 11.8086 1.1198 24.7795
HuCC-T1 CTRP2 4.9748 7.4523 4.3281 9.5848
SNU-869 CTRP2 5.6909 8.3717 4.5744 6.8967
SNU-245 CTRP2 6.9509 13.8704 2.8588 11.6061
SNU-1196 CTRP2 7.9452 14.7388 3.1613 8.8179
SNU-308 CTRP2 8.2414 14.6025 3.4288 7.3563
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 888.T CTRP2 4.9487 10.8512 2.6762 16.3243
SK-ES-1 CTRP2 5.6414 7.403 5.0056 5.2119
SaOS-2 CTRP2 5.7773 7.6121 5.0281 4.8168
A-673 CTRP2 5.7812 7.2788 5.1961 4.1082
CAL-78 CTRP2 5.933 10.8726 3.5368 10.7373
HOS CTRP2 6.199 8.0722 5.1563 3.4449
SJSA-1 CTRP2 6.6797 10.6212 4.2615 6.3518
Hs 822.T CTRP2 6.8808 8.0682 5.6152 0.6943
SK-N-MC CTRP2 7.5318 12.5419 3.9361 6.3581
TC71 CTRP2 7.5947 8.8698 5.6224 0.2586
MHH-ES-1 CTRP2 8.1567 10.4553 5.252 0.8689
G-292 clone A141B1 CTRP2 8.3663 14.0898 3.753 5.9415
MG-63 CTRP2 9.8068 19.748 2.0172 10.4222
SW1353 CTRP2 12.04 23.9834 1.4422 9.6264
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 66 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 3.0418 5.0735 2.9725 20.2387
HCC1954 CTRP2 4.6242 6.0935 4.4808 9.9647
HCC1500 CTRP2 4.7442 11.312 2.2616 18.3997
CAL-85-1 CTRP2 5.1166 8.5669 3.9457 10.7908
BT-20 CTRP2 5.2852 8.4286 4.1727 9.4664
Hs 578T CTRP2 5.5564 7.7062 4.7785 6.3442
T-47D CTRP2 5.7801 8.4965 4.5917 6.6364
ZR-75-30 CTRP2 5.7867 7.761 4.9629 5.0692
HCC2218 CTRP2 5.8002 7.4562 5.126 4.3592
HCC1806 CTRP2 6.0489 8.1696 4.9856 4.4419
BT-474 CTRP2 6.0495 10.1184 4.0117 8.5307
MDA-MB-453 CTRP2 6.2079 8.5653 4.9175 4.4305
MDA-MB-361 CTRP2 6.2791 7.463 5.5199 1.791
HCC38 CTRP2 6.3894 11.7262 3.4857 10.0786
HCC1419 CTRP2 6.4418 9.4001 4.6852 4.9907
CAL-120 CTRP2 6.554 8.6121 5.1565 2.8561
CAL-51 CTRP2 6.5546 9.658 4.6432 4.9754
SK-BR-3 CTRP2 6.6685 9.7881 4.6637 4.7041
MDA-MB-468 CTRP2 6.7463 11.5731 3.841 7.9805
Hs 578Bst CTRP2 6.9642 9.2663 5.1204 2.426
ZR-75-1 CTRP2 7.2017 11.5555 4.1836 5.8465
HCC1143 CTRP2 7.4577 12.4479 3.9303 6.4897
HCC202 CTRP2 7.4843 13.7757 3.3032 8.9618
JIMT-1 CTRP2 7.4887 12.1076 4.1156 5.7015
HMC-1-8 CTRP2 7.7491 12.1889 4.2502 4.8129
MCF-7 CTRP2 7.9154 14.0416 3.4772 7.6259
BT-549 CTRP2 8.0231 13.9688 3.5852 7.05
MDA-MB-231 CTRP2 8.0783 16.9273 2.1908 12.2821
HDQ-P1 CTRP2 8.1869 10.059 5.42 0.4416
CAMA-1 CTRP2 8.4266 9.8935 5.5723 0.1237
KPL-1 CTRP2 9.0038 25.3945 -1.2887 21.2822
HCC1428 CTRP2 9.7899 21.289 1.2724 12.922
BT 239 CTRP2 3.3139 4.0692 3.3136 18.1919
BT 228 CTRP2 3.6972 5.0906 3.6666 15.7403
BT 416 CTRP2 3.7169 5.2536 3.6684 15.6704
BT 139 CTRP2 3.887 5.0487 3.8695 14.4317
BT 231 CTRP2 4.4115 8.4583 3.3044 15.1039
BT164 CTRP2 4.7585 7.2052 4.2142 10.5993
BT 428 CTRP2 4.9118 6.8306 4.5309 8.9514
BT 172 CTRP2 5.0003 6.7499 4.657 8.2215
BT 286 CTRP2 5.1234 8.7764 3.8513 11.1625
BT 504 CTRP2 5.1706 8.3629 4.0953 10.0507
BT 271 CTRP2 5.2186 7.6086 4.5 8.2838
BT 440 CTRP2 5.24 8.1852 4.247 9.2655
BT 159 CTRP2 5.3616 8.5382 4.191 9.2162
BT 330 CTRP2 5.8426 8.6537 4.568 6.6067
BT 359 CTRP2 5.8945 7.5481 5.1642 3.9994
BT 131 CTRP2 6.0542 7.7198 5.2148 3.4681
BT 145 CTRP2 6.1659 11.9025 3.216 11.6036
BT 328 CTRP2 6.1967 8.481 4.9506 4.3121
BT 422 CTRP2 6.2809 10.0641 4.2281 7.1887
BT 333 CTRP2 6.3226 9.4138 4.5855 5.6156
BT 248 CTRP2 6.3623 8.2934 5.1726 3.0949
BT 482 CTRP2 6.5218 9.8053 4.5454 5.437
BT 444 CTRP2 6.7135 9.9175 4.6332 4.7584
BT 498 CTRP2 6.7719 23.1864 -1.9281 26.4199
BT 187 CTRP2 6.8648 9.8735 4.763 3.9937
BT 232 CTRP2 6.9067 10.373 4.5498 4.8
BT 245 CTRP2 6.9513 8.6845 5.3817 1.4459
BT147 CTRP2 7.3255 24.24 -2.009 25.6244
BT 112 CTRP2 7.3529 12.5451 3.8095 7.1334
BT 320 CTRP2 7.4093 8.6361 5.6337 0.3094
BT 340 CTRP2 7.7196 11.9166 4.3594 4.4248
BT 216 CTRP2 7.7549 15.1809 2.8113 10.4633
BT 224 CTRP2 8.3177 13.5785 3.9613 5.2061
BT 179 CTRP2 8.4376 15.7057 3.0333 8.6006
⏷ Show the Full List of 66 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAS-1 CTRP2 4.3294 18.3146 -1.5726 30.538
Hs 683 CTRP2 4.6059 6.7166 4.2507 10.8756
SF539 CTRP2 4.6215 6.6719 4.2842 10.7042
GaMG CTRP2 4.626 6.083 4.4858 9.9414
D283 Med CTRP2 5.2131 9.8042 3.4336 12.676
SF268 CTRP2 5.3132 8.0973 4.3592 8.6337
U-118MG CTRP2 5.5577 7.1689 5.0385 5.2718
KG-1-C CTRP2 5.7127 7.3576 5.0943 4.6837
U-251MG CTRP2 5.8031 8.2955 4.712 6.0844
SW1088 CTRP2 5.9946 9.8621 4.0939 8.293
SW1783 CTRP2 6.1426 13.7158 2.2902 15.3066
DK-MG CTRP2 6.2361 10.8526 3.7981 9.0682
42-MG-BA CTRP2 6.2442 8.809 4.8249 4.7532
NMC-G1 CTRP2 6.2995 8.259 5.1419 3.329
Daoy CTRP2 6.3038 8.8803 4.8364 4.5985
KNS-60 CTRP2 6.366 10.036 3.5454 4.4555
KNS-42 CTRP2 6.4693 9.0311 4.8887 4.0968
SF126 CTRP2 6.709 11.5568 3.8206 8.1287
SNU-489 CTRP2 6.7282 8.8153 5.179 2.5101
SNU-738 CTRP2 6.7576 10.62 4.3204 5.9794
SNB-75 CTRP2 6.8801 9.8208 4.7992 3.824
YKG-1 CTRP2 6.9733 10.3795 4.5936 4.5211
KNS-81 CTRP2 7.0664 13.9492 2.9081 11.2127
Becker CTRP2 7.1843 10.7717 4.55 4.3916
CCF-STTG1 CTRP2 7.2312 8.7997 5.4849 0.8259
SNU-626 CTRP2 7.2634 11.6163 4.1973 5.6992
SNU-1105 CTRP2 7.3152 9.193 5.3605 1.1605
SNU-201 CTRP2 7.3607 11.8073 4.1725 5.6573
U-87MG ATCC CTRP2 7.4074 9.8819 5.1073 1.9576
KALS-1 CTRP2 7.5866 12.8192 3.8402 6.6622
M059K CTRP2 7.7093 13.0098 3.8325 6.5165
8-MG-BA CTRP2 7.7415 11.5146 4.561 3.6192
A-172 CTRP2 7.7454 9.8667 5.2957 1.0193
GB-1 CTRP2 8.2191 13.7806 3.8037 5.9359
T98G CTRP2 8.2502 15.3344 3.0843 8.671
ONS-76 CTRP2 8.2955 10.2912 5.3775 0.4874
GOS-3 CTRP2 8.3699 16.1285 2.7842 9.6396
YH-13 CTRP2 8.5276 14.6239 3.6054 6.2991
TM-31 CTRP2 8.7119 13.1002 4.4133 3.1047
GMS-10 CTRP2 8.7525 16.4327 2.8968 8.6797
DBTRG-05MG CTRP2 9.7008 16.393 3.5062 5.2958
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-7 CTRP2 5.0164 10.61 2.8569 15.4541
JHUEM-1 CTRP2 5.5361 6.8878 5.1493 4.8739
HEC-151 CTRP2 5.6076 6.6602 5.325 3.988
HEC-1-A CTRP2 5.7779 7.5791 5.045 4.7451
ESS-1 CTRP2 6.0438 7.3553 5.3884 2.7584
MFE-319 CTRP2 6.0676 8.1397 5.016 4.2782
JHUEM-2 CTRP2 6.1801 14.1437 2.1073 15.9218
MFE-296 CTRP2 6.274 8.1962 5.1533 3.3253
JHUEM-3 CTRP2 6.5155 14.059 2.4226 14.0882
EFE-184 CTRP2 6.5846 8.5433 5.2115 2.5857
HEC-59 CTRP2 7.0264 12.153 3.7649 7.8285
HEC-6 CTRP2 7.1343 10.5831 4.6065 4.2353
HEC-265 CTRP2 7.3667 8.6238 5.6201 0.3603
HEC-1-B CTRP2 7.8342 12.3382 4.2348 4.7624
HEC-108 CTRP2 7.9162 9.0145 5.692 0.0778
HEC-251 CTRP2 7.9286 9.414 5.5553 0.2691
RL95-2 CTRP2 8.0777 12.8947 4.1292 4.8617
AN3-CA CTRP2 8.2094 15.3304 3.0583 8.8293
EN CTRP2 8.4728 14.4266 3.663 6.1493
HEC-50B CTRP2 9.381 16.9602 3.0532 7.2913
Ishikawa (Heraklio) 02 ER- CTRP2 6.849 8.1174 5.5767 0.8524
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 4.1777 6.1422 3.9797 13.1323
KMRC-3 CTRP2 4.3421 6.7281 3.9635 12.7115
TUHR10TKB CTRP2 4.5322 5.8919 4.4331 10.4175
CAL-54 CTRP2 5.0231 8.1876 4.0363 10.6431
KMRC-2 CTRP2 5.3624 9.3156 3.8106 10.7902
BFTC-909 CTRP2 6.1691 7.893 5.2218 3.2244
VMRC-RCW CTRP2 6.219 9.2261 4.5966 5.7568
769-P CTRP2 6.2664 8.5318 4.9806 4.0611
VMRC-RCZ CTRP2 6.3658 9.6505 4.5017 5.8899
TUHR4TKB CTRP2 6.966 12.1942 3.6997 8.1941
SNU-1272 CTRP2 7.0447 12.0937 3.8076 7.6243
RCC10RGB CTRP2 7.0583 9.2908 5.1682 2.1244
KMRC-1 CTRP2 7.5509 9.239 5.4596 0.6739
ACHN CTRP2 7.786 13.64 3.5818 7.4006
Caki-1 CTRP2 7.8096 12.3683 4.2048 4.9112
786-O CTRP2 7.909 12.3063 4.2975 4.4247
OS-RC-2 CTRP2 8.0224 9.7749 5.4589 0.4273
KMRC-20 CTRP2 8.2051 13.0148 4.1531 4.6134
TUHR14TKB CTRP2 8.4866 10.3823 5.4213 0.3293
Caki-2 CTRP2 10.9375 18.7788 3.1443 5.2882
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OUMS-23 CTRP2 3.0667 5.4114 2.9431 20.2611
SW948 CTRP2 3.8008 8.6661 2.5921 19.4701
T84 CTRP2 3.8321 7.3762 3.1702 17.1643
HCT 15 CTRP2 4.1906 5.8233 4.077 12.7431
SW48 CTRP2 4.3473 10.3461 2.3555 18.9871
NCI-H747 CTRP2 4.4923 6.7974 4.0985 11.7746
C2BBe1 CTRP2 4.5362 9.1582 3.1031 15.5966
SNU-C1 CTRP2 4.6688 6.8605 4.2619 10.6572
SW1116 CTRP2 4.7495 7.2375 4.1912 10.7136
SNU-407 CTRP2 4.8767 7.417 4.2441 10.1712
DLD-1 CTRP2 4.9908 6.2485 4.833 7.5807
SNU-61 CTRP2 5.0417 9.5233 3.412 13.1512
SNU-1033 CTRP2 5.0792 9.0673 3.6687 12.0142
HCC-56 CTRP2 5.3588 6.356 5.1928 5.1711
KM12 CTRP2 5.4611 7.1604 4.9483 5.8725
CL-11 CTRP2 5.5171 7.633 4.777 6.4409
SK-CO-1 CTRP2 5.6368 9.1965 4.117 8.9226
SNU-C5 CTRP2 5.7595 9.1137 4.2663 8.0419
LS513 CTRP2 5.9128 7.4262 5.241 3.6401
SW1417 CTRP2 6.0036 9.1007 4.4821 6.6458
COLO 678 CTRP2 6.0536 9.9339 4.1073 8.122
SNU-C2A CTRP2 6.1563 11.7161 3.3012 11.2735
HCT 8 CTRP2 6.2084 8.1711 5.1145 3.6035
LS411N CTRP2 6.59 8.4856 5.2431 2.4493
LoVo CTRP2 6.6807 13.5757 2.795 12.3366
CCK-81 CTRP2 6.9083 11.76 3.8707 7.5876
LS123 CTRP2 6.9394 11.2526 4.1433 6.4164
COLO205 CTRP2 7.4338 8.6525 5.6377 0.2901
SNU-C4 CTRP2 7.5164 8.6065 5.6879 0.1658
RKO CTRP2 7.5735 13.1177 3.6868 7.2946
CW-2 CTRP2 7.6241 12.4255 4.0549 5.7526
COLO201 CTRP2 7.683 9.4097 5.4523 0.6134
MDST8 CTRP2 7.7327 10.8884 4.8427 2.5739
HT-55 CTRP2 7.7378 9.6774 5.37 0.8059
HT-29 CTRP2 7.7812 9.1384 5.5979 0.2402
NCI-H716 CTRP2 7.7927 13.9331 3.4449 7.9317
NCI-H508 CTRP2 7.8611 13.8386 3.5377 7.4661
GP2d CTRP2 7.9841 16.0753 2.5392 11.1405
LS1034 CTRP2 7.9984 11.3734 4.7783 2.5279
SW620 CTRP2 8.0807 9.9282 5.4251 0.4764
RCM-1 [Human ESC] CTRP2 8.0976 12.0264 4.5418 3.2808
LS180 CTRP2 8.1261 10.5588 5.1956 1.0473
HCT 116 CTRP2 8.3103 9.7854 5.5677 0.1504
SNU-503 CTRP2 10.1739 27.246 -1.3431 19.7009
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-6 CTRP2 4.2987 6.6953 3.9289 12.9658
SNU-182 CTRP2 4.3688 7.2032 3.8071 13.2357
SNU-878 CTRP2 4.3881 6.5523 4.0765 12.154
Li-7 CTRP2 4.8264 7.3398 4.2264 10.3724
SNU-761 CTRP2 5.1567 6.7704 4.2732 3.2478
SNU-886 CTRP2 5.4816 19.3594 -1.0877 27.0141
PLC/PRF/5 CTRP2 5.5215 6.7277 5.2076 4.6769
SNU-423 CTRP2 5.5852 6.8992 5.1925 4.5782
JHH-2 CTRP2 5.8044 7.4284 5.1434 4.2772
JHH-1 CTRP2 5.8983 6.5519 5.6606 1.9192
JHH-5 CTRP2 6.2006 10.1703 4.1101 7.8311
JHH-6 CTRP2 6.7494 8.0585 5.5465 1.0605
HLF CTRP2 6.8433 11.0524 4.171 7.4528
SNU-387 CTRP2 6.9826 13.0684 3.2803 9.8705
HuH-1 CTRP2 7.2428 10.0885 4.9125 2.8811
SNU-475 CTRP2 7.2473 9.2409 5.3023 1.4239
SNU-449 CTRP2 7.3662 13.6818 3.2635 9.3069
SK-HEP-1 CTRP2 7.3985 10.863 4.6485 3.7102
Hep-G2 CTRP2 7.5654 9.0539 5.5399 0.4544
JHH-4 CTRP2 7.8393 11.3824 4.6815 3.0514
Hep 3B2.1-7 CTRP2 8.0681 9.2332 5.6711 0.0769
SNU-398 CTRP2 8.561 11.4007 5.0595 1.1482
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 132 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LC-1F CTRP2 0.0965 20.1294 -11.3292 35.3965
NCI-H810 CTRP2 2.9644 4.8714 2.9159 20.6833
LUDLU-1 CTRP2 3.2995 12.1089 0.5034 27.9682
NCI-H1341 CTRP2 3.4573 7.8039 2.6021 20.3651
NCI-H1568 CTRP2 3.4999 6.7567 3.0449 18.5811
NCI-H2081 CTRP2 3.8278 5.9367 3.6539 15.373
NCI-H2141 CTRP2 3.9013 10.5148 1.8432 22.0057
NCI-H522 CTRP2 3.913 8.6689 2.7053 18.7389
NCI-H211 CTRP2 3.9352 6.6672 3.5468 15.4457
NCI-H1944 CTRP2 3.9952 19.6633 -2.5401 33.0943
EBC-1 CTRP2 4.0345 5.8719 3.8955 13.8725
NCI-H1666 CTRP2 4.0803 8.4686 2.9649 17.2933
DV-90 CTRP2 4.269 8.0297 3.352 15.2819
NCI-H1581 CTRP2 4.3014 6.8787 3.8635 13.2062
Calu-3 CTRP2 4.3101 6.7159 3.9336 12.9155
DMS 53 CTRP2 4.3328 6.0245 4.1819 11.9304
HCC95 CTRP2 4.4593 5.3363 4.4445 10.6101
SK-MES-1 CTRP2 4.703 7.4352 4.0579 11.3612
ChaGo-K-1 CTRP2 4.7322 8.4229 3.6402 12.9575
NCI-H1694 CTRP2 4.9034 7.3378 4.3063 9.855
NCI-H446 CTRP2 4.9269 7.501 4.2577 9.9881
HCC15 CTRP2 4.9386 7.5816 4.2331 10.0566
T3M-10 CTRP2 4.9522 11.2247 2.4959 17.0223
NCI-H2106 CTRP2 4.9589 6.7061 4.6308 8.4363
LCLC-97TM1 CTRP2 5.008 6.8612 4.6194 8.3466
NCI-H1703 CTRP2 5.0245 9.5284 3.3934 13.2665
NCI-H1563 CTRP2 5.0475 6.6658 4.7408 7.7688
COLO 668 CTRP2 5.1164 7.3437 4.5202 8.4565
NCI-H358 CTRP2 5.1272 6.5844 4.8576 7.0994
SW1271 CTRP2 5.1773 8.2685 4.147 9.8231
NCI-H1693 CTRP2 5.2248 7.8682 4.3838 8.7415
NCI-H647 CTRP2 5.2381 8.3784 4.1523 9.6588
EKVX CTRP2 5.2667 8.1391 4.2947 9.007
Sq-1 CTRP2 5.2728 8.925 3.9196 10.5391
NCI-H1355 CTRP2 5.3027 9.278 3.7744 11.0722
NCI-H1155 CTRP2 5.3327 7.4424 4.6899 7.2345
EPLC-272H CTRP2 5.3761 10.5211 3.2274 13.1633
NCI-H1105 CTRP2 5.4132 7.9052 4.547 7.6287
NCI-H841 CTRP2 5.4173 8.6589 4.1837 9.1213
DMS 454 CTRP2 5.4474 8.1668 4.4523 7.9412
COR-L88 CTRP2 5.4498 10.1389 3.4827 11.9567
DMS 273 CTRP2 5.4775 6.6555 5.1947 4.8413
COR-L105 CTRP2 5.5472 7.6956 4.7751 6.3795
NCI-H2087 CTRP2 5.5544 8.774 4.2525 8.5338
NCI-H2170 CTRP2 5.5919 7.9421 4.6963 6.6048
NCI-H2110 CTRP2 5.6012 7.5115 4.9152 5.6773
NCI-H1755 CTRP2 5.6741 9.9823 3.759 10.3384
PC-14 CTRP2 5.7551 9.3125 4.1634 8.4818
COR-L51 CTRP2 5.8796 20.5397 -1.341 26.8016
NCI-H2196 CTRP2 5.8844 8.9643 4.449 7.021
NCI-H1915 CTRP2 5.917 7.1694 5.3724 3.0804
HCC44 CTRP2 5.9317 13.0811 2.4317 15.1826
VMRC-LCD CTRP2 6.0048 10.568 3.7495 9.7126
Lu-65 CTRP2 6.0352 13.1647 2.4766 14.803
Lu-99 CTRP2 6.049 8.1927 4.9741 4.4899
NCI-H322 CTRP2 6.0525 7.2784 5.4341 2.5494
NCI-H1573 CTRP2 6.0642 15.4656 1.3503 18.8552
NCI-H520 CTRP2 6.113 8.4071 4.9197 4.5966
KNS-62 CTRP2 6.1362 7.3356 5.4736 2.2277
NCI-H1395 CTRP2 6.1479 10.4885 3.908 8.7761
RERF-LC-MS CTRP2 6.1946 10.9441 3.7186 9.4771
HOP-62 CTRP2 6.2295 8.9574 4.7391 5.1397
COLO 699 CTRP2 6.3522 10.7521 3.9419 8.2549
NCI-H1339 CTRP2 6.4011 7.8534 5.4171 2.0226
NCI-H2029 CTRP2 6.4431 11.4604 3.6611 9.2563
HARA [Human squamous cell lung carcinoma] CTRP2 6.4462 10.4152 4.1841 7.0753
SBC-5 CTRP2 6.4835 7.8971 5.4535 1.7532
HCC4006 CTRP2 6.52 8.398 5.2365 2.5804
DMS 114 CTRP2 6.5413 9.4534 4.7342 4.6194
NCI-H1651 CTRP2 6.5473 10.0479 4.4447 5.813
NCI-H661 CTRP2 6.6128 11.3411 3.8535 8.1585
RERF-LC-A1 CTRP2 6.6238 10.7373 4.1616 6.861
NCI-H2228 CTRP2 6.6445 11.3937 3.8519 8.1101
HCC1438 CTRP2 6.7751 8.7622 5.2356 2.221
MOR/CPR CTRP2 6.7917 7.8974 5.6416 0.6844
HCC2935 CTRP2 6.8537 8.7092 5.3109 1.8264
HCC2279 CTRP2 6.9426 12.6088 3.4774 9.1398
HOP-92 CTRP2 6.9762 9.4452 5.0438 2.7108
SK-LU-1 CTRP2 7.0009 10.5891 4.5114 4.8146
LK2 CTRP2 7.0233 9.1021 5.2339 1.9165
NCI-H838 CTRP2 7.0314 13.007 3.3475 9.5172
LXF 289 CTRP2 7.0325 12.4393 3.6284 8.3755
NCI-H1092 CTRP2 7.1345 13.0122 3.4219 9.0462
Calu-1 CTRP2 7.1438 9.4776 5.1345 2.1508
NCI-H23 CTRP2 7.1801 13.406 3.2619 9.6153
LC-1/sq-SF CTRP2 7.2208 8.7655 5.4941 0.8053
BEN CTRP2 7.2252 8.1792 5.7294 0.1846
HCC1588 CTRP2 7.3117 8.9921 5.4446 0.8893
CAL-12T CTRP2 7.3637 10.3681 4.8581 2.941
NCI-H2023 CTRP2 7.377 12.6333 3.7837 7.201
HCC1195 CTRP2 7.3917 11.7066 4.2422 5.3323
RERF-LC-Ad1 CTRP2 7.453 8.3204 5.7652 0.0732
LOU-NH91 CTRP2 7.4544 13.2362 3.5451 8.0421
LCLC-103H CTRP2 7.4767 9.0053 5.5191 0.5567
NCI-H226 CTRP2 7.5203 9.0251 5.5311 0.5004
NCI-H2009 CTRP2 7.5225 12.6911 3.8577 6.6857
NCI-H196 CTRP2 7.5414 12.8297 3.8038 6.874
NCI-H1435 CTRP2 7.6037 13.6078 3.4703 8.1132
HCC366 CTRP2 7.6191 12.6115 3.9624 6.1281
HCC78 CTRP2 7.647 10.6462 4.9021 2.4494
NCI-H460 CTRP2 7.6785 11.0524 4.7357 3.032
IA-LM CTRP2 7.6903 12.2496 4.183 5.1549
NCI-H727 CTRP2 7.6987 11.8292 4.3871 4.3436
NCI-H2030 CTRP2 7.6997 10.9078 4.8145 2.714
NCI-H1650 CTRP2 7.7437 12.9139 3.9018 6.1932
NCI-H1299 CTRP2 7.7719 11.1714 4.7374 2.9192
A-549 CTRP2 7.7896 12.4785 4.1396 5.1924
NCI-H2126 CTRP2 7.792 10.6807 4.9698 2.0564
SHP-77 CTRP2 7.8245 9.3559 5.5347 0.3478
HCC1833 CTRP2 7.9144 13.031 3.9596 5.7316
NCI-H2342 CTRP2 7.9362 10.6692 5.0533 1.6376
COR-L95 CTRP2 7.9405 10.4771 5.1375 1.3606
NCI-H2286 CTRP2 7.9757 9.4935 5.5448 0.2728
NCI-H2122 CTRP2 8.0026 9.4166 5.5832 0.1998
NCI-H650 CTRP2 8.0378 14.1786 3.4947 7.383
Calu-6 CTRP2 8.0906 14.1853 3.527 7.1833
RERF-LC-Ad2 CTRP2 8.1395 13.8902 3.7 6.4428
NCI-H2085 CTRP2 8.1416 9.9189 5.454 0.3888
NCI-H441 CTRP2 8.3089 13.8571 3.8255 5.7365
NCI-H1184 CTRP2 8.3371 10.1468 5.4484 0.3291
NCI-H1975 CTRP2 8.3733 20.5271 0.6404 17.0263
NCI-H1623 CTRP2 8.428 11.9678 4.754 2.2019
HCC2108 CTRP2 8.7794 16.5148 2.8756 8.722
HCC827 CTRP2 9.1034 17.8442 2.4578 9.8124
NCI-H2405 CTRP2 9.3669 16.8363 3.102 7.131
NCI-H2172 CTRP2 9.5161 16.9202 3.1553 6.759
SW1573 CTRP2 9.7904 23.0046 0.4469 15.4728
NCI-H1869 CTRP2 9.8689 20.2336 1.8279 10.9835
NCI-H1792 CTRP2 9.9775 18.1993 2.848 7.3159
HCC1171 CTRP2 10.8054 22.396 1.4141 11.1449
NCI-H1373 CTRP2 11.9049 22.9183 1.8464 8.5175
Hs 888.Lu CTRP2 6.0138 9.5974 4.2424 7.6326
⏷ Show the Full List of 132 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 4.7841 9.9466 2.9641 15.5596
P-STS CTRP2 5.9039 12.4139 2.7418 14.0256
SYO-1 CTRP2 5.9313 10.1483 3.8974 9.2397
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 5.2495 14.0816 1.3455 20.5722
A2780 CTRP2 4.0682 6.7513 3.6604 14.6366
SNU-119 CTRP2 4.1842 10.9581 1.9058 21.0675
COV434 CTRP2 4.3494 6.8297 3.9334 12.805
TYK-nu CTRP2 5.0426 7.0466 4.5766 8.4226
Kuramochi CTRP2 5.2155 12.0405 2.3304 17.0744
OAW28 CTRP2 5.6371 11.2897 3.075 13.2318
OAW42 CTRP2 5.6549 7.2605 5.0876 4.8427
DOV13 CTRP2 5.691 6.8443 5.3219 3.7955
COV362 CTRP2 5.8389 11.0131 3.3868 11.5448
TOV-112D CTRP2 6.0269 8.0503 5.0268 4.311
JHOS-2 CTRP2 6.0805 12.6377 2.7778 13.533
OVCAR-5 CTRP2 6.2591 8.8123 4.835 4.6838
EFO-27 CTRP2 6.2636 8.7389 4.8752 4.5075
OC 314 CTRP2 6.5057 8.8423 5.0088 3.5393
OV7 CTRP2 6.6065 9.5818 4.7194 4.5739
ONCO-DG-1 CTRP2 6.6402 10.8806 4.1031 7.0758
MCAS CTRP2 6.7467 10.7509 4.2477 6.2978
ES2 CTRP2 6.8533 9.1766 5.0903 2.6916
Caov-3 CTRP2 6.9609 13.0032 3.2962 9.8433
SNU-840 CTRP2 7.0249 12.9387 3.3764 9.4113
OVISE CTRP2 7.0359 10.7192 4.4729 4.9187
IGROV-1 CTRP2 7.1178 10.2065 4.7756 3.5824
OV56 CTRP2 7.2223 8.2674 5.6951 0.2557
SNU-8 CTRP2 7.3195 12.1938 3.9566 6.5894
OVK18 CTRP2 7.353 13.779 3.206 9.5566
RMG-I CTRP2 7.3766 14.1732 3.0298 10.2161
OV-90 CTRP2 7.479 11.0089 4.6316 3.6728
JHOC-5 CTRP2 7.8812 9.6457 5.4479 0.5175
JHOM-1 CTRP2 7.892 12.5158 4.1884 4.8681
EFO-21 CTRP2 7.9348 9.7872 5.4164 0.5669
OVTOKO CTRP2 8.0402 15.7679 2.7288 10.3384
OVCAR-4 CTRP2 8.2914 14.2476 3.6303 6.5106
OVCAR-8 CTRP2 8.3571 13.0617 4.2245 4.1656
FU-OV-1 CTRP2 8.5213 10.28 5.4717 0.2362
SK-OV-3 CTRP2 8.6421 14.7661 3.6116 6.1312
COV644 CTRP2 8.8882 19.2664 1.6272 13.0334
HEY A8 CTRP2 9.998 17.5435 3.1599 6.1952
OVSAHO CTRP2 11.9605 21.3392 2.5829 6.1366
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 5.9114 8.3969 4.7556 5.6795
Aska-SS CTRP2 6.5252 10.1809 4.3619 6.1956
Rh18 CTRP2 3.9777 6.1508 3.759 14.5375
Rh41 CTRP2 4.2639 6.4126 3.9896 12.8392
A-204 CTRP2 4.7137 7.6561 3.9716 11.6751
GCT CTRP2 4.9625 6.1348 4.8378 7.6472
TE 617.T CTRP2 4.9697 8.1258 4.0131 10.8668
HT-1080 CTRP2 5.2207 7.2754 4.6562 7.6477
TE 441.T CTRP2 5.2802 6.1025 5.1938 5.3956
G-402 CTRP2 5.3218 8.4198 4.2114 9.2229
SK-LMS-1 CTRP2 5.6105 8.1704 4.6012 6.9592
Hs 729.T CTRP2 5.6586 10.5759 3.4496 11.6533
BT-16 CTRP2 5.7069 7.984 4.7807 6.0013
Tm87-16 CTRP2 5.9172 11.4331 3.2433 11.9773
G-401 CTRP2 5.9385 10.8793 3.5382 10.7209
TTC-709 CTRP2 5.9668 10.7328 3.6352 10.2625
KYM-1 CTRP2 6.0368 7.8779 5.1213 3.8947
SW982 CTRP2 6.1443 11.4596 3.4195 10.8108
MES-SA CTRP2 6.1855 7.2535 5.5531 1.8083
BT-12 CTRP2 6.936 7.6815 5.7972 0.1576
RKN CTRP2 7.557 9.0642 5.5321 0.4779
SK-UT-1 CTRP2 8.68 16.5 2.8164 9.0791
RD CTRP2 8.8576 18.7856 1.8386 12.3529
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 8.0711 10.0554 5.3718 0.6062
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 CTRP2 5.7839 7.5347 5.0724 4.6179
NCI-H28 CTRP2 5.7865 10.1087 3.7935 9.964
MSTO-211H CTRP2 6.5295 10.2887 4.3118 6.3972
ACC-MESO-1 CTRP2 6.642 10.6269 4.2301 6.5455
NCI-H2452 CTRP2 6.7222 10.7819 4.214 6.4779
IST-Mes1 CTRP2 7.5825 15.0245 2.7628 10.9241
JL-1 CTRP2 8.7104 15.5493 3.2877 7.2681
NCI-H2052 CTRP2 9.6667 16.2729 3.5405 5.2109
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 CTRP2 5.5566 8.2142 4.5302 7.3732
PaCa-3 CTRP2 5.947 8.0128 4.9779 4.6747
VCaP CTRP2 6.0164 7.4895 5.2984 3.1904
DU145 CTRP2 6.2855 9.6416 4.4426 6.2815
LNCaP clone FGC CTRP2 7.2562 10.916 4.5295 4.373
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 5.0338 6.7416 4.6957 7.9803
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 2.452 4.4103 2.4209 24.0375
HGC-27 CTRP2 4.0766 5.7257 3.9748 13.4604
GSS CTRP2 4.4133 6.1159 4.2443 11.46
SNU-601 CTRP2 4.5108 6.887 4.0837 11.7793
ECC10 CTRP2 4.522 5.2913 4.5131 10.1723
HuG1-N CTRP2 4.6773 10.0532 2.8115 16.4185
KATO III CTRP2 5.4009 7.384 4.7843 6.6853
IM95 CTRP2 5.5899 12.0725 2.6437 15.0556
OCUM-1 CTRP2 5.7626 18.2624 -0.301 24.4766
Hs 746.T CTRP2 5.9854 8.8776 4.5783 6.277
SNU-1 CTRP2 6.3718 11.8766 3.3964 10.4779
SNU-216 CTRP2 6.4091 8.4764 5.1173 3.2468
MKN1 CTRP2 6.448 11.0062 3.8913 8.2927
KE-39 CTRP2 6.4968 10.2041 4.3285 6.3843
GSU CTRP2 6.6629 7.4008 5.786 0.3294
SNU-620 CTRP2 6.8236 8.5642 5.3596 1.6764
Fu97 CTRP2 7.0193 13.1158 3.2847 9.791
NUGC-4 CTRP2 7.0619 9.3296 5.1525 2.1802
ECC12 CTRP2 7.0633 10.2306 4.7275 3.8503
MKN74 CTRP2 7.1196 11.8578 3.9777 6.8105
NUGC-3 CTRP2 7.1304 11.5599 4.1309 6.1687
MKN45 CTRP2 7.2784 8.456 5.6468 0.3403
23132/87 CTRP2 7.4159 12.2463 3.9987 6.2761
AGS CTRP2 7.895 9.2052 5.6178 0.1745
SH-10-TC CTRP2 7.9372 13.5321 3.7362 6.5772
MKN7 CTRP2 7.9406 12.4688 4.2415 4.6011
LMSU CTRP2 8.6204 14.8015 3.5813 6.2731
SNU-719 CTRP2 10.3572 19.5005 2.4806 8.1511
SNG-M CTRP2 6.5328 9.4777 4.7159 4.7095
SNU-1077 CTRP2 8.0746 13.7499 3.7239 6.4374
SNU-685 CTRP2 8.2224 15.9129 2.7862 9.8477
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
B-CPAP CTRP2 4.8256 6.6489 4.5113 9.2655
SW579 CTRP2 5.0657 6.3101 4.8936 7.1369
8505C CTRP2 5.7396 8.4922 4.558 6.8622
TT2609-C02 CTRP2 6.1722 8.4905 4.9262 4.4594
8305C CTRP2 6.2069 10.7687 3.8163 9.0472
CGTH-W-1 CTRP2 6.3342 9.113 4.7445 4.9296
CAL-62 CTRP2 6.9334 8.8992 5.2723 1.8774
ML-1 [Human leukemia] CTRP2 7.0277 9.7435 4.9361 3.0672
TT CTRP2 7.2666 12.6399 3.7015 7.7036
FTC-238 CTRP2 7.4276 11.9829 4.1338 5.7159
FTC-133 CTRP2 8.0099 11.4893 4.733 2.6782
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-33 CTRP2 4.9706 6.3711 4.7694 7.8767
SCC-25 CTRP2 4.9747 9.5518 3.3353 13.6182
PE/CA-PJ49 CTRP2 5.1926 9.4773 3.575 12.1409
CAL-27 CTRP2 5.4094 9.6463 3.6903 11.1854
YD-8 CTRP2 5.4095 8.804 4.1054 9.4637
SNU-1076 CTRP2 5.4428 9.274 3.9044 10.2249
PE/CA-PJ34 (clone C12) CTRP2 5.5686 8.7737 4.2655 8.449
FaDu CTRP2 5.6934 7.1591 5.173 4.4019
BICR 22 CTRP2 5.7625 6.6366 5.4898 2.9389
BICR 18 CTRP2 5.938 7.3558 5.2981 3.3486
PE/CA-PJ15 CTRP2 5.9506 9.236 4.3698 7.2218
SCC-9 CTRP2 5.9797 8.1918 4.9163 4.8679
BHY CTRP2 5.9808 8.0878 4.9692 4.6435
HSC-2 CTRP2 6.1632 8.0613 5.1332 3.607
HSC-4 CTRP2 6.1941 9.7872 4.2962 7.0636
BICR 31 CTRP2 6.5255 8.8496 5.0197 3.4627
BICR 16 CTRP2 7.0079 10.4642 4.5768 4.538
Detroit 562 CTRP2 7.4255 10.6884 4.7477 3.2901
SCC-4 CTRP2 7.4715 9.7786 5.1897 1.5995
HSC-3 CTRP2 7.8818 9.0262 5.6758 0.1004
BICR 6 CTRP2 7.9282 9.7273 5.4368 0.5208
PE/CA-PJ41 (clone D2) CTRP2 8.1685 14.2767 3.5354 7.043
BICR 56 CTRP2 8.2318 9.5023 5.6371 0.0867
SNU-899 CTRP2 8.3765 12.8801 4.319 3.7937
SNU-1066 CTRP2 8.4936 11.1177 5.1421 0.9628
SNU-1041 CTRP2 10.0014 17.2291 3.3041 5.6864
SNU-46 CTRP2 11.1571 25.2985 0.2723 14.1458
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J CTRP2 4.5083 6.271 4.301 10.9688
U-BLC1 CTRP2 4.5098 5.3611 4.4953 10.2725
JMSU-1 CTRP2 4.6503 6.5233 4.3697 10.2991
UM-UC-1 CTRP2 4.8003 8.7699 3.5439 13.1811
253J-BV CTRP2 4.8108 7.496 4.1418 10.7479
BFTC-905 CTRP2 4.8206 5.6603 4.7907 8.2545
CAL-29 CTRP2 4.9625 7.7566 4.1773 10.2205
HT-1197 CTRP2 5.1741 9.4189 3.5864 12.1354
BC-3C CTRP2 5.4961 7.2326 4.9485 5.7865
TCCSUP CTRP2 5.8831 9.4355 4.2126 8.0157
UM-UC-3 CTRP2 6.0558 7.826 5.1631 3.6824
T24 CTRP2 6.1528 8.5269 4.8923 4.6374
SW1710 CTRP2 6.4201 9.1342 4.8003 4.5475
KMBC-2 CTRP2 6.5173 9.7886 4.5503 5.4243
639V CTRP2 6.8224 8.5364 5.3717 1.6317
HT-1376 CTRP2 7.3401 12.03 4.0505 6.1789
KU-19-19 CTRP2 7.6147 9.958 5.1894 1.4673
RT-4 CTRP2 7.6403 12.7701 3.9007 6.3435
5637 CTRP2 7.7985 10.119 5.2165 1.2238
RT-112 CTRP2 7.8999 13.2098 3.865 6.1225
SCaBER CTRP2 8.1166 11.9811 4.5735 3.144
J82 CTRP2 8.1587 13.2595 4.0099 5.2187
VM-CUB-1 CTRP2 9.3647 17.083 2.9858 7.5564
647V CTRP2 9.8418 19.203 2.2966 9.4133
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.3178 8.2898 5.7255 0.1612

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4213).
2 Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19084-9.