Details of the Drug

General Information of Drug (ID: DMIYFQ5)

Drug Name
SB216763
Synonyms
280744-09-4; SB 216763; 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione; SB216763; SB-216763; 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione; 1H-Pyrrole-2,5-dione, 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-; CHEMBL102714; 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione; SR-01000076052; Tocris-1616; Lopac-S-3442; AC1L41YI; Lopac0_000934; SCHEMBL30251; MLS001074894; cid_176158; BDBM8296; GTPL8015; CTK8B4807; CHEBI:91421; AOB5004; SYN1075; EX-A291
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 371.2
Logarithm of the Partition Coefficient (xlogp) 3.9
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 2
Chemical Identifiers
Formula
C19H12Cl2N2O2
IUPAC Name
3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione
Canonical SMILES
CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl
InChI
InChI=1S/C19H12Cl2N2O2/c1-23-9-13(11-4-2-3-5-15(11)23)17-16(18(24)22-19(17)25)12-7-6-10(20)8-14(12)21/h2-9H,1H3,(H,22,24,25)
InChIKey
JCSGFHVFHSKIJH-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
176158
ChEBI ID
CHEBI:91421
CAS Number
280744-09-4
TTD ID
D0A1YQ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glycogen synthase kinase-3 alpha (GSK-3A) TTRZQE3 GSK3A_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Androgen receptor (AR) OTUBKAZZ ANDR_HUMAN Drug Response [3]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Gene/Protein Processing [4]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Gene/Protein Processing [5]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Post-Translational Modifications [6]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [7]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [7]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Gene/Protein Processing [8]
Glycogen synthase kinase-3 beta (GSK3B) OTL3L14B GSK3B_HUMAN Gene/Protein Processing [9]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Gene/Protein Processing [10]
Rapamycin-insensitive companion of mTOR (RICTOR) OTCC58QJ RICTR_HUMAN Gene/Protein Processing [10]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 5.2052 7.1776 2.6463 1.0426
CHSA8926 GDSC1; GDSC2 3.4879 5.444 2.3958 5.3985
CAL-72 GDSC1; GDSC2 3.6808 6.1611 2.1892 6.1927
G-292 clone A141B1 GDSC1; GDSC2 4.1377 6.5756 2.3145 4.3598
CAL-78 GDSC2 4.1608 12.017 -0.3478 19.2006
EW-24 GDSC1; GDSC2 4.5106 6.9804 2.3628 3.3624
TC-71 GDSC1; GDSC2 4.5133 6.1885 2.7175 1.4557
SaOS-2 GDSC1; GDSC2 4.7891 6.2246 2.8354 0.6597
NY GDSC1; GDSC2 4.9419 8.2882 2.0238 4.5244
CADO-ES1 GDSC1; GDSC2 5.0286 7.7744 2.3056 2.8494
HuO-3N1 GDSC1; GDSC2 5.0385 9.3661 1.5827 6.8546
HOS GDSC1; GDSC2 5.039 7.7449 2.3244 2.7368
HuO9 GDSC1; GDSC2 5.0567 8.6462 1.9291 4.8559
SJSA-1 GDSC1; GDSC2 5.2021 8.2122 2.2088 3.1037
MG-63 GDSC1; GDSC2 5.213 6.775 2.8047 0.4822
A-673 GDSC1; GDSC2 5.2946 6.5633 2.9123 0.1872
CHSA0011 GDSC1; GDSC2 5.4885 7.6864 2.5728 1.0894
U2OS GDSC1; GDSC2 5.5044 7.649 2.5946 0.9946
ES1 GDSC1; GDSC2 5.5318 7.2986 2.7392 0.5008
EW-16 GDSC1; GDSC2 5.5373 9.7802 1.6989 5.308
EW-18 GDSC1; GDSC2 5.5465 7.6727 2.6038 0.9287
ES5 GDSC1; GDSC2 5.5855 8.0819 2.4595 1.4574
NOS-1 [Human HNSCC] GDSC1; GDSC2 5.609 7.8048 2.5798 0.9687
ES6 GDSC1; GDSC2 5.6303 8.0639 2.4874 1.3031
ES4 GDSC1; GDSC2 5.6492 7.7262 2.6272 0.7762
SK-ES-1 GDSC1; GDSC2 5.6579 7.4175 2.7455 0.4234
EW-13 GDSC1; GDSC2 5.7169 7.5975 2.703 0.508
EW-1 GDSC1; GDSC2 5.73 7.5837 2.7132 0.4741
MHH-ES-1 GDSC1; GDSC2 5.7932 7.3475 2.8209 0.2126
EW-7 GDSC1; GDSC2 5.7935 7.9545 2.6011 0.7689
EW-12 GDSC2 5.8213 7.7805 2.6772 0.5267
ES7 GDSC1; GDSC2 5.8397 7.8791 2.6483 0.5984
ES8 GDSC1; GDSC2 5.8894 7.4375 2.8244 0.1825
U-CH2 GDSC2 5.9229 7.616 2.7747 0.2601
H-EMC-SS GDSC1; GDSC2 6.1168 8.4252 2.5576 0.7125
EW-22 GDSC1; GDSC2 6.2635 8.0461 2.7488 0.214
SK-PN-DW GDSC1; GDSC2 6.3578 8.1172 2.7579 0.1793
EW-3 GDSC1; GDSC2 6.5795 8.536 2.6933 0.2273
CHSA0108 GDSC1; GDSC2 6.6511 8.5347 2.7189 0.1753
EW-11 GDSC1; GDSC2 6.8364 9.4091 2.4816 0.5698
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 3.6826 5.0902 2.7174 2.8978
MV4-11 GDSC1; GDSC2 1.7542 6.8171 0.1422 24.6106
MOLM-16 GDSC1; GDSC2 2.9429 4.7902 2.2521 7.9622
ALL-PO GDSC1; GDSC2 3.1043 5.7942 1.9 9.6522
SIG-M5 GDSC2 3.1856 4.0964 2.8159 3.6232
RS4;11 GDSC1; GDSC2 3.3049 10.3762 -0.2194 21.0354
BL-41 GDSC1; GDSC2 3.4786 5.0684 2.5756 4.2892
ST486 GDSC1; GDSC2 3.4858 4.6082 2.8097 2.7965
RCH-ACV GDSC1; GDSC2 3.5258 5.2476 2.5233 4.494
MY-M12 GDSC1; GDSC2 3.5854 4.776 2.8011 2.6062
BV-173 GDSC1; GDSC2 3.6135 5.7345 2.3492 5.3613
P32/ISH GDSC1; GDSC2 3.6243 4.7156 2.8582 2.1648
NK-92MI GDSC2 3.626 5.1754 2.6348 3.5422
Kasumi-1 GDSC1; GDSC2 3.6427 5.485 2.4947 4.3759
SU-DHL-8 GDSC2 3.6544 5.2995 2.5947 3.7234
SU-DHL-4 GDSC1; GDSC2 3.6688 4.9489 2.7763 2.5672
OCI-Ly7 GDSC1; GDSC2 3.6792 5.0973 2.7115 2.9418
MC116 GDSC1; GDSC2 3.6965 5.3981 2.577 3.7327
JeKo-1 GDSC1; GDSC2 3.7 4.9806 2.7826 2.4596
H9 GDSC1; GDSC2 3.7007 5.2037 2.675 3.1175
SUP-B8 GDSC1; GDSC2 3.736 5.309 2.6487 3.1986
Reh GDSC1; GDSC2 3.7415 5.4063 2.6053 3.4528
MHH-CALL-2 GDSC1; GDSC2 3.7743 5.5915 2.5385 3.7896
JVM-3 GDSC1 3.7985 5.8379 2.4356 5.4403
Ramos.2G6.4C10 GDSC1; GDSC2 3.8048 5.6092 2.5514 3.6405
SU-DHL-1 GDSC2 3.8175 10.5409 0.1166 17.9088
OCI-Ly19 GDSC1; GDSC2 3.825 5.3237 2.7029 2.6754
DB GDSC1; GDSC2 3.8891 6.0852 2.3796 4.5049
DoHH2 GDSC1; GDSC2 3.8987 8.8054 1.0448 12.6265
KMS-11 GDSC1; GDSC2 3.9298 5.6818 2.602 3.0644
MHH-CALL-4 GDSC2 3.9494 6.4498 2.245 5.195
NALM-6 GDSC1; GDSC2 3.9618 5.5153 2.7016 2.4106
BALL-1 GDSC1; GDSC2 3.9984 6.0564 2.4691 3.7208
HEL GDSC1; GDSC2 4.0061 5.4515 2.7589 1.9979
BE-13 GDSC1; GDSC2 4.1197 7.8986 1.6596 8.3873
SUP-B15 GDSC1; GDSC2 4.1665 5.5887 2.791 1.5587
NKM-1 GDSC1; GDSC2 4.2085 8.7778 1.293 10.3744
SU-DHL-6 GDSC1; GDSC2 4.2261 6.5826 2.3695 3.8521
EM-2 GDSC1; GDSC2 4.2319 9.8755 0.7691 13.332
SU-DHL-10 GDSC2 4.2455 5.4436 2.896 0.9234
KMS-12-BM GDSC1; GDSC2 4.2484 5.9109 2.6937 1.9568
697 GDSC1; GDSC2 4.2858 6.1841 2.592 2.4573
CTV-1 GDSC1; GDSC2 4.2916 6.4137 2.49 3.0256
MEG-01 GDSC1; GDSC2 4.2944 6.421 2.4884 3.0299
SCC-3 GDSC2 4.3086 13.8548 -1.1465 22.1786
A3/Kawakami GDSC1; GDSC2 4.3161 5.7341 2.8089 1.2573
NB4 GDSC1; GDSC2 4.3199 5.4708 2.9213 0.729
CMK GDSC1 4.3555 5.875 2.7691 1.7493
RL GDSC1; GDSC2 4.392 6.7329 2.4043 3.3363
LAMA-84 GDSC1; GDSC2 4.4053 7.0745 2.2534 4.1863
Daudi GDSC1; GDSC2 4.4412 6.3925 2.5886 2.2247
ATN-1 GDSC1; GDSC2 4.4431 6.4349 2.5707 2.3188
Karpas-422 GDSC1; GDSC2 4.4537 6.0876 2.7295 1.4733
U266B1 GDSC1; GDSC2 4.4587 8.4126 1.6504 7.6616
OPM-2 GDSC1; GDSC2 4.4674 6.4823 2.5634 2.3201
MM1.S GDSC1; GDSC2 4.494 6.4633 2.587 2.1528
ALL-SIL GDSC1; GDSC2 4.5004 6.3391 2.6454 1.8372
SR GDSC1; GDSC2 4.5155 6.715 2.4866 2.6626
OCI-M1 GDSC1; GDSC2 4.5342 6.2915 2.6842 1.5935
Mono-Mac-6 GDSC1; GDSC2 4.5561 7.6565 2.0766 4.9304
L-540 GDSC1; GDSC2 4.5742 9.0597 1.4178 8.7811
Farage GDSC1; GDSC2 4.5787 6.2706 2.7163 1.3801
SUP-M2 GDSC1; GDSC2 4.5939 5.866 2.8893 0.6122
OCI-AML-5 GDSC1; GDSC2 4.6082 5.7647 2.9347 0.4398
JSC-1 GDSC1; GDSC2 4.6175 6.8559 2.4821 2.5265
LC4-1 GDSC1; GDSC2 4.6334 7.2446 2.3158 3.4152
Karpas-45 GDSC1; GDSC2 4.649 6.5478 2.6346 1.6912
DND-41 GDSC1; GDSC2 4.6541 6.8974 2.4844 2.4586
SKM-1 GDSC1; GDSC2 4.6706 5.8819 2.9165 0.4594
Jurkat GDSC1; GDSC2 4.6829 6.1287 2.8255 0.7861
MOLT-4 GDSC1; GDSC2 4.6875 8.2023 1.9044 5.6813
L-363 GDSC1; GDSC2 4.6992 6.0498 2.864 0.6236
U-698-M GDSC1; GDSC2 4.7098 7.8445 2.0861 4.5854
P12-Ichikawa GDSC1; GDSC2 4.7219 6.5716 2.6622 1.4664
SU-DHL-5 GDSC1; GDSC2 4.7534 5.6745 3.0245 0.1361
YT GDSC1; GDSC2 4.7744 6.3242 2.7894 0.8497
MOLM-13 GDSC1; GDSC2 4.79 7.5105 2.2877 3.3115
CTB-1 GDSC1; GDSC2 4.8023 7.5154 2.2926 3.2644
RPMI-8402 GDSC1; GDSC2 4.8065 6.5804 2.7005 1.1956
MOLT-13 GDSC1; GDSC2 4.8366 8.1419 2.0268 4.6939
JJN-3 GDSC1; GDSC2 4.8589 6.7491 2.6564 1.3373
CML-T1 GDSC1; GDSC2 4.8947 7.0668 2.5408 1.8394
RPMI-8866 GDSC1; GDSC2 4.9076 8.6858 1.8182 5.7563
TUR GDSC1; GDSC2 4.9225 9.462 1.4615 7.7813
WSU-DLCL2 GDSC1; GDSC2 4.9441 6.3392 2.8576 0.4768
BC-1 GDSC1; GDSC2 4.9442 7.1101 2.5479 1.7445
SU-DHL-16 GDSC1; GDSC2 4.9467 6.2108 2.9063 0.3329
OCI-AML-2 GDSC1; GDSC2 4.9485 6.1427 2.9318 0.2668
MHH-PREB-1 GDSC1; GDSC2 4.9555 6.7242 2.7127 0.9974
KOPN-8 GDSC1; GDSC2 4.9648 7.0858 2.5686 1.6223
RC-K8 GDSC1; GDSC2 4.991 6.4358 2.8407 0.5018
HAL-01 GDSC1; GDSC2 4.9949 10.5742 0.9776 10.3671
GR-ST GDSC1; GDSC2 4.9999 7.8618 2.2509 3.1813
L-1236 GDSC1; GDSC2 5.0014 7.3095 2.4927 1.9406
K-562 GDSC1; GDSC2 5.0257 6.657 2.7708 0.7153
KM-H2 GDSC1; GDSC2 5.0349 7.8353 2.2823 2.9628
SUP-T1 GDSC1; GDSC2 5.0488 7.8377 2.2889 2.9074
HL-60 GDSC1; GDSC2 5.0756 6.0924 2.996 0.1038
NU-DUL-1 GDSC1; GDSC2 5.0948 6.5068 2.8564 0.3963
Karpas-231 GDSC1; GDSC2 5.1068 6.4048 2.8982 0.2821
Sc-1 GDSC1 5.1531 6.9801 2.7008 1.0898
ME1 GDSC1; GDSC2 5.1628 6.2343 2.9783 0.111
SK-MM-2 GDSC1; GDSC2 5.1632 7.13 2.646 1.0807
AMO1 GDSC1; GDSC2 5.1892 6.4717 2.9055 0.2343
HT GDSC1; GDSC2 5.1999 6.6744 2.8366 0.3982
MOLP-8 GDSC1; GDSC2 5.2265 6.7879 2.8054 0.4728
RPMI-6666 GDSC1; GDSC2 5.2375 6.7972 2.8064 0.4639
Granta-519 GDSC1; GDSC2 5.2433 6.9845 2.7383 0.6744
P31/FUJ GDSC1; GDSC2 5.2456 6.6106 2.8774 0.2757
OCI-AML-3 GDSC1; GDSC2 5.2593 6.7544 2.8308 0.3851
BC-3 GDSC2 5.2715 6.775 2.8281 0.3864
ML-2 GDSC1; GDSC2 5.2755 7.0618 2.7225 0.7064
CCRF-CEM GDSC1; GDSC2 5.2792 7.5137 2.5454 1.3902
Karpas-620 GDSC1; GDSC2 5.2804 6.585 2.8995 0.2161
LP-1 GDSC1; GDSC2 5.3058 6.9212 2.788 0.4806
NOMO-1 GDSC1; GDSC2 5.3083 6.8557 2.8131 0.4089
JURL-MK1 GDSC1; GDSC2 5.317 6.7815 2.8434 0.3271
SUP-HD1 GDSC1; GDSC2 5.3173 7.4896 2.573 1.2378
JVM-2 GDSC1; GDSC2 5.3184 7.8403 2.4298 1.8631
ROS-50 GDSC1; GDSC2 5.3232 7.2255 2.6799 0.8212
KE-37 GDSC1; GDSC2 5.3235 6.579 2.9173 0.1701
L-428 GDSC1; GDSC2 5.3543 7.0105 2.7745 0.4938
HC-1 GDSC1; GDSC2 5.3573 6.9122 2.8118 0.3893
Karpas-299 GDSC1; GDSC2 5.4081 6.7362 2.8934 0.1893
IM-9 GDSC1; GDSC2 5.43 6.7264 2.9047 0.1639
GA-10 GDSC1; GDSC2 5.4612 6.995 2.822 0.3195
WIL2 NS GDSC1; GDSC2 5.4717 7.7295 2.5482 1.1999
Raji GDSC1; GDSC2 5.4767 6.5735 2.9726 0.0664
EoL-1 GDSC1; GDSC2 5.4839 10.9349 1.1311 8.5141
QIMR-WIL GDSC1; GDSC2 5.5028 12.6133 0.3441 12.6247
TK [Human B-cell lymphoma] GDSC1; GDSC2 5.5048 6.9121 2.8675 0.2093
A4/Fukuda GDSC1; GDSC2 5.5208 6.9651 2.8548 0.2285
DG-75 GDSC1; GDSC2 5.5535 7.7834 2.5637 1.0713
MLMA GDSC1; GDSC2 5.5664 7.3041 2.751 0.4514
TALL-1 [Human adult T-ALL] GDSC2 5.5783 8.622 2.2322 2.4877
MOLT-16 GDSC1; GDSC2 5.6193 7.1252 2.835 0.2367
WSU-NHL GDSC1; GDSC2 5.6307 7.3234 2.7689 0.3768
KG-1 GDSC1; GDSC2 5.638 7.2598 2.7945 0.3145
HH [Human lymphoma] GDSC1; GDSC2 5.6385 8.2661 2.4098 1.6154
RPMI-8226 GDSC1; GDSC2 5.6581 8.0931 2.4884 1.2747
NCI-H929 GDSC1; GDSC2 5.6703 7.2254 2.8187 0.2527
HDLM-2 GDSC1; GDSC2 5.6717 7.8053 2.6066 0.8302
ARH-77 GDSC1; GDSC2 5.7 7.5012 2.7315 0.4402
MN-60 GDSC1; GDSC2 5.7049 7.9215 2.5762 0.9114
P30/OHK GDSC1; GDSC2 5.707 8.4862 2.3527 1.7923
Loucy GDSC1; GDSC2 5.7454 7.3006 2.8199 0.2278
KMOE-2 GDSC1; GDSC2 5.7645 7.5968 2.7219 0.4358
EB2 GDSC1; GDSC2 5.7757 7.3762 2.8046 0.2475
Hs 445 GDSC2 5.7924 7.7065 2.6929 0.4984
EJM GDSC1; GDSC2 5.7988 7.3251 2.8307 0.1944
THP-1 GDSC1; GDSC2 5.8043 7.5018 2.771 0.3058
KY821 GDSC1; GDSC2 5.8196 7.1862 2.8852 0.1115
CESS GDSC1; GDSC2 5.8216 7.2469 2.8655 0.1366
VAL GDSC1; GDSC2 5.8243 7.4545 2.795 0.2511
Ku812 GDSC1; GDSC2 5.8345 7.4048 2.816 0.2101
Karpas-1106P GDSC1; GDSC2 5.8559 7.6256 2.7465 0.3404
KCL-22 GDSC1; GDSC2 5.8712 7.52 2.7893 0.2479
CRO-AP2 GDSC1; GDSC2 5.9236 7.6666 2.7573 0.2941
CA46 GDSC1; GDSC2 6.0353 7.8499 2.7342 0.3045
Namalwa GDSC1; GDSC2 6.0549 7.9511 2.7058 0.3574
BONNA-12 GDSC2 6.0981 8.5015 2.5214 0.8347
EHEB GDSC1 6.2065 7.7487 2.8297 0.1428
GDM-1 GDSC1; GDSC2 6.3599 7.9985 2.7987 0.1263
Jiyoye GDSC1; GDSC2 6.4258 8.0607 2.8005 0.1143
PL-21 GDSC1; GDSC2 6.4542 8.3459 2.7139 0.2243
VL51 GDSC1; GDSC2 6.494 8.343 2.729 0.1926
PF-382 GDSC1; GDSC2 7.4381 24.5389 -4.0825 24.3368
DEL GDSC1; GDSC2 9.167 23.6142 -2.4648 17.0169
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FLO-1 GDSC1; GDSC2 4.6617 7.9598 2.0018 5.1632
KYAE-1 GDSC1; GDSC2 5.0283 6.7537 2.7342 0.8495
ESO-26 GDSC1; GDSC2 5.043 10.501 1.0457 9.8847
OACM5.1 C GDSC1; GDSC2 5.3772 8.1245 2.3399 2.2159
HCE-4 GDSC1; GDSC2 5.4607 7.4893 2.6375 0.8713
KYSE-50 GDSC1; GDSC2 5.5642 7.1799 2.795 0.3416
ESO-51 GDSC1; GDSC2 5.7217 7.5649 2.7168 0.4685
KYSE-220 GDSC1; GDSC2 5.8799 7.908 2.6537 0.5622
OACP4 C GDSC1; GDSC2 6.3482 8.3153 2.6863 0.3007
SK-GT-4 GDSC2 6.5091 8.5268 2.6713 0.2822
TE-12 GDSC1; GDSC2 7.5018 17.5524 -0.6846 13.4402
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 5.4996 9.0426 2.0078 3.7195
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-MC-IXC GDSC1; GDSC2 3.8019 5.6461 2.5315 3.7698
CHP-212 GDSC1; GDSC2 3.9925 6.3217 2.3374 4.5323
NB1 GDSC1; GDSC2 4.1593 5.8689 2.6602 2.2902
NH-12 GDSC1; GDSC2 4.251 10.9254 0.264 15.9899
SK-N-AS GDSC1; GDSC2 4.3659 6.4608 2.5136 2.7612
SK-N-DZ GDSC1; GDSC2 4.5225 6.4612 2.6039 2.0215
NB69 GDSC1; GDSC2 4.6105 11.1384 0.4287 14.2282
SJNB-13 GDSC1; GDSC2 4.654 7.4772 2.2216 3.9117
NB(TU)1 GDSC1 5.0228 7.4911 2.426 2.7899
SJNB-14 GDSC1; GDSC2 5.0259 10.3213 1.1203 9.5048
SJNB-5 GDSC1; GDSC2 5.0514 11.2528 0.689 11.8175
SK-N-FI GDSC1; GDSC2 5.0547 13.0406 -0.1799 16.1826
MHH-NB-11 GDSC1; GDSC2 5.0793 9.7614 1.4226 7.6859
SJNB-17 GDSC1; GDSC2 5.1326 7.1289 2.6322 1.1651
TGW GDSC1; GDSC2 5.1785 7.0784 2.6735 0.9586
SJNB-7 GDSC1; GDSC2 5.2499 6.6383 2.8692 0.293
Kelly GDSC1; GDSC2 5.2561 6.6245 2.8764 0.2739
SK-N-BE(2)-M17 GDSC1; GDSC2 5.2993 8.0751 2.3207 2.4055
SK-N-SH GDSC1; GDSC2 5.4555 7.3749 2.6792 0.731
SJNB-6 GDSC1; GDSC2 5.4958 7.2266 2.7514 0.4853
IMR-5 GDSC1; GDSC2 5.4985 7.5502 2.6304 0.8692
LA-N-6 GDSC1; GDSC2 5.5166 7.0883 2.8097 0.3263
KP-N-RT-BM-1 GDSC2 5.5905 8.0671 2.4677 1.4186
SJNB-10 GDSC1; GDSC2 5.6081 7.7129 2.6149 0.8455
GI-ME-N GDSC1; GDSC2 5.6717 8.3189 2.4041 1.6072
GOTO GDSC1; GDSC2 5.6934 7.4943 2.7314 0.4434
CHP-126 GDSC1; GDSC2 5.7841 7.4804 2.771 0.3129
KP-N-YN GDSC1; GDSC2 5.9698 8.0871 2.6236 0.6005
SJNB-12 GDSC1; GDSC2 6.0237 11.3827 1.2585 6.8501
KP-N-YS GDSC1; GDSC2 6.2141 8.1084 2.7094 0.2969
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 5.4493 7.2772 2.7137 0.6233
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-468 GDSC1; GDSC2 4.1536 5.633 2.7638 1.7186
MCF-7 GDSC1; GDSC2 4.2001 8.7779 1.2868 10.3972
Evsa-T GDSC2 4.262 5.8007 2.7506 1.6252
Hs 578T GDSC1; GDSC2 4.3936 7.6269 1.9838 5.7882
AU565 GDSC1; GDSC2 4.4803 6.6948 2.4751 2.7739
HCC2157 GDSC1; GDSC2 4.4866 6.0061 2.7812 1.1817
MDA-MB-231 GDSC1; GDSC2 4.5531 6.6932 2.5181 2.4236
CAL-120 GDSC1; GDSC2 4.6123 6.3287 2.709 1.3698
JIMT-1 GDSC1; GDSC2 4.6287 6.5421 2.6263 1.7529
EFM-192A GDSC1; GDSC2 4.6314 6.6962 2.5606 2.0836
MFM-223 GDSC1; GDSC2 4.6755 7.8973 2.0399 4.8987
T-47D GDSC1; GDSC2 4.8116 6.9497 2.5475 1.9057
HCC2218 GDSC1; GDSC2 4.8747 7.0924 2.5194 1.963
HCC1428 GDSC1; GDSC2 4.978 6.8327 2.6795 1.1104
HCC1599 GDSC2 5.0115 7.7214 2.3196 2.7916
BT-474 GDSC1; GDSC2 5.0299 6.5421 2.8167 0.5526
OCUB-M GDSC1; GDSC2 5.063 7.2379 2.554 1.573
CAL-148 GDSC2 5.0708 6.2305 2.9466 0.1886
BT-549 GDSC1; GDSC2 5.0791 7.2593 2.5531 1.5594
MDA-MB-175-VII GDSC1; GDSC2 5.093 6.4177 2.8882 0.3114
ZR-75-30 GDSC1; GDSC2 5.1042 7.5282 2.4527 1.9999
HCC1500 GDSC1; GDSC2 5.2456 7.3994 2.5759 1.2888
DU4475 GDSC1; GDSC2 5.2513 6.3799 2.9599 0.1187
HCC1937 GDSC1; GDSC2 5.2578 7.2486 2.6419 1.0112
CAL-51 GDSC1; GDSC2 5.3409 7.5081 2.5765 1.1979
MDA-MB-330 GDSC2 5.3419 7.4702 2.5922 1.1344
MDA-MB-453 GDSC1; GDSC2 5.4327 7.3878 2.6646 0.7935
CAMA-1 GDSC1; GDSC2 5.4553 9.3459 1.8473 4.6237
HDQ-P1 GDSC1; GDSC2 5.5001 7.3598 2.7036 0.622
MDA-MB-415 GDSC2 5.5243 7.458 2.6766 0.6926
HCC1569 GDSC1; GDSC2 5.5286 8.0871 2.4304 1.6301
HCC1187 GDSC1; GDSC2 5.5736 7.7228 2.5962 0.9327
MDA-MB-436 GDSC2 5.7013 7.4701 2.7433 0.4083
HCC70 GDSC1; GDSC2 5.7053 7.3424 2.7904 0.298
HCC1395 GDSC1; GDSC2 5.7327 7.3887 2.7843 0.3015
MRK-nu-1 GDSC1; GDSC2 5.7997 7.2315 2.863 0.1439
HCC1806 GDSC1; GDSC2 5.8005 7.2065 2.8718 0.1316
UACC-893 GDSC1; GDSC2 5.8049 7.6658 2.7126 0.4398
HCC202 GDSC1 5.8142 7.8458 2.6503 0.755
HCC1419 GDSC1; GDSC2 5.8969 7.4636 2.8181 0.1901
CAL-85-1 GDSC1; GDSC2 5.9081 8.1247 2.5845 0.7486
COLO 824 GDSC1; GDSC2 5.9166 7.8275 2.6974 0.4294
HCC38 GDSC1; GDSC2 5.9449 7.7257 2.7444 0.3125
BT-483 GDSC1; GDSC2 5.9629 7.4915 2.832 0.1545
HCC1954 GDSC1; GDSC2 6.2082 8.0772 2.7182 0.2811
BT-20 GDSC1; GDSC2 6.2365 7.7025 2.8553 0.084
MDA-MB-157 GDSC1; GDSC2 6.2554 8.096 2.7287 0.2488
MDA-MB-361 GDSC1; GDSC2 6.2605 8.2763 2.6676 0.3654
YMB-1-E GDSC2 6.5146 8.3413 2.7368 0.1774
EFM-19 GDSC1; GDSC2 6.6967 8.4338 2.7684 0.1099
HCC1143 GDSC2 6.9036 9.2742 2.5547 0.3833
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-251MG GDSC1; GDSC2 3.3866 4.8927 2.5898 4.4508
MOG-G-CCM GDSC1; GDSC2 3.4154 5.8555 2.1322 7.264
GaMG GDSC1; GDSC2 3.5434 7.7922 1.2685 12.2716
8-MG-BA GDSC1; GDSC2 3.6055 4.8036 2.8021 2.5529
D-566MG GDSC1; GDSC2 3.6708 5.4937 2.5113 4.2031
GB-1 GDSC1; GDSC2 3.674 5.0325 2.7394 2.782
T98G GDSC1; GDSC2 3.7583 6.2482 2.2046 5.9009
SF539 GDSC1; GDSC2 3.8212 7.2204 1.7716 8.4389
H4 GDSC1; GDSC2 3.8221 5.3957 2.6665 2.9012
Hs 683 GDSC1; GDSC2 3.8523 5.6694 2.5554 3.5106
CAS-1 GDSC1; GDSC2 3.9226 5.786 2.5474 3.4082
DK-MG GDSC1; GDSC2 4.0221 5.3919 2.7959 1.7617
NMC-G1 GDSC1; GDSC2 4.0551 8.0946 1.5157 9.4186
Daoy GDSC1; GDSC2 4.0988 7.0344 2.0665 5.9496
SK-MG-1 GDSC2 4.103 6.9077 2.1309 5.5476
SW1783 GDSC1; GDSC2 4.1101 7.6364 1.7811 7.6698
M059J GDSC1; GDSC2 4.1543 5.7735 2.7007 2.0712
YKG-1 GDSC1; GDSC2 4.2236 6.2133 2.5408 2.857
YH-13 GDSC1; GDSC2 4.3077 7.7993 1.842 6.8459
PFSK-1 GDSC1; GDSC2 4.3556 8.6385 1.4681 8.9821
LN-405 GDSC1; GDSC2 4.4599 7.3102 2.1777 4.5249
D-423MG GDSC1; GDSC2 4.5153 6.667 2.5081 2.5454
SF126 GDSC1; GDSC2 4.5185 6.3199 2.6636 1.7187
42-MG-BA GDSC1; GDSC2 4.5459 8.0586 1.8796 6.112
D-263MG GDSC1; GDSC2 4.5845 7.2224 2.2965 3.6087
LN-229 GDSC1; GDSC2 4.5907 6.3462 2.6904 1.4905
SF295 GDSC1; GDSC2 4.7544 6.3646 2.7639 0.9738
KINGS-1 GDSC1; GDSC2 4.9086 7.2949 2.4499 2.274
DBTRG-05MG GDSC1; GDSC2 4.9497 7.066 2.5693 1.6365
U-87MG ATCC GDSC1; GDSC2 5.0333 6.8595 2.6944 1.0015
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 5.1211 7.5184 2.4655 1.925
LNZTA3WT4 GDSC2 5.206 9.9405 1.4202 7.4501
GI-1 GDSC1; GDSC2 5.2082 7.0191 2.7099 0.7987
D-502MG GDSC1; GDSC2 5.2201 7.1899 2.6481 1.0224
D-245MG GDSC2 5.2225 8.1902 2.2297 2.9666
D-247MG GDSC1; GDSC2 5.2421 7.5803 2.5002 1.6267
U-118MG GDSC1; GDSC2 5.3133 7.1994 2.6857 0.8076
D-336MG GDSC1; GDSC2 5.3817 7.8531 2.4556 1.677
AM-38 GDSC1; GDSC2 5.4062 6.8157 2.865 0.2451
D-542MG GDSC1; GDSC2 5.4075 6.8853 2.8408 0.2971
D283 Med GDSC1; GDSC2 5.4659 8.6697 2.1526 3.0237
Becker GDSC1; GDSC2 5.4866 7.3642 2.6964 0.6552
ONS-76 GDSC1; GDSC2 5.4891 7.0887 2.799 0.363
KNS-42 GDSC1; GDSC2 5.5393 6.9855 2.8544 0.2236
A-172 GDSC1; GDSC2 5.5475 21.4183 -3.945 27.6321
LN-18 GDSC2 5.5488 16.3884 -1.4611 20.3772
D-392MG GDSC1; GDSC2 5.5883 7.4198 2.7171 0.5342
KNS-81-FD GDSC1; GDSC2 5.6333 7.7247 2.6211 0.8073
Onda 10 GDSC1; GDSC2 5.6449 7.3897 2.7505 0.4164
SW1088 GDSC1; GDSC2 6.2515 14.1509 0.1111 12.2378
MOG-G-UVW GDSC2 6.2736 8.0064 2.766 0.1853
SNB-75 GDSC1; GDSC2 6.3086 7.9665 2.7918 0.1432
Onda 11 GDSC1; GDSC2 6.3358 8.1937 2.7239 0.2369
KALS-1 GDSC1; GDSC2 6.4558 8.8609 2.5324 0.6098
SF268 GDSC1; GDSC2 6.5436 8.5342 2.6811 0.2559
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 5.2597 7.6516 2.4793 1.702
TGBC1TKB GDSC1; GDSC2 5.5217 7.1682 2.7829 0.3891
TGBC24TKB GDSC1; GDSC2 6.0314 7.7873 2.7546 0.2658
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC1; GDSC2 4.7958 6.3676 2.7819 0.861
AN3-CA GDSC1; GDSC2 4.8019 9.3848 1.4176 8.2863
EN GDSC1; GDSC2 5.0275 6.2782 2.9133 0.2785
KLE GDSC1; GDSC2 5.0294 10.8076 0.8888 10.7816
ESS-1 GDSC1; GDSC2 5.1792 6.7768 2.7902 0.5462
MFE-319 GDSC1; GDSC2 5.841 7.1491 2.9049 0.0862
MFE-296 GDSC1; GDSC2 5.8866 7.4357 2.824 0.1838
MFE-280 GDSC1; GDSC2 6.7993 9.5758 2.4064 0.784
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB2241-RCC GDSC1; GDSC2 2.1754 4.8465 1.4752 15.5094
KTCTL-13 GDSC1; GDSC2 3.3807 6.2916 1.8858 8.9163
NCC010 GDSC2 3.3952 6.4596 1.8137 9.3279
RCC10RGB GDSC1; GDSC2 3.5272 4.9509 2.6716 3.558
BFTC-909 GDSC1; GDSC2 3.5901 5.1379 2.6266 3.6819
LB996-RCC GDSC2 3.7216 7.0551 1.777 8.6633
A-704 GDSC2 3.8505 7.1423 1.8323 7.9882
KTCTL-26A GDSC1; GDSC2 4.0114 5.6278 2.6804 2.44
A-498 GDSC1; GDSC2 4.0508 8.5088 1.308 10.6779
KTCTL-1M GDSC1; GDSC2 4.0976 6.1282 2.5006 3.3299
769-P GDSC1; GDSC2 4.1844 7.2285 2.0324 5.9662
CAL-54 GDSC1; GDSC2 4.2057 8.189 1.5799 8.6648
KTCTL-195 GDSC1; GDSC2 4.6319 6.4837 2.6531 1.6215
KMRC-1 GDSC1; GDSC2 4.7581 8.6774 1.7257 6.5842
KTCTL-140 GDSC1; GDSC2 4.8346 6.9816 2.5459 1.8905
HA7-RCC GDSC1; GDSC2 5.0006 6.7753 2.713 0.9558
KMRC-20 GDSC1; GDSC2 5.0446 8.3787 2.0441 4.236
UO-31 GDSC1; GDSC2 5.1098 6.8839 2.7193 0.8399
TK-10 GDSC1; GDSC2 5.1893 8.3116 2.1578 3.3904
SN12C GDSC1; GDSC2 5.2087 7.0141 2.7121 0.7906
VMRC-RCZ GDSC1; GDSC2 5.3167 7.189 2.6913 0.7856
ACHN GDSC1; GDSC2 5.3407 6.9785 2.7808 0.4826
VMRC-RCW GDSC1; GDSC2 5.4002 7.0806 2.767 0.4908
786-O GDSC1; GDSC2 5.6981 7.8044 2.6181 0.7746
Caki-1 GDSC1; GDSC2 5.7365 9.0459 2.1335 2.7677
RXF 393L GDSC1; GDSC2 5.8853 8.3582 2.4855 1.1023
LB1047-RCC GDSC1; GDSC2 5.8859 8.2177 2.54 0.9106
BB65-RCC GDSC1; GDSC2 5.9724 7.6379 2.7851 0.2271
SW13 GDSC1; GDSC2 5.9889 7.562 2.8171 0.1711
NCC021 GDSC2 6.288 8.5551 2.578 0.5685
KTCTL-21 GDSC2 6.6112 8.613 2.6782 0.2439
OS-RC-2 GDSC1; GDSC2 6.6755 19.7577 -2.2966 20.8646
SW156 GDSC1; GDSC2 6.6869 8.653 2.6913 0.2066
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H747 GDSC1; GDSC2 3.9157 6.3266 2.2811 5.0327
HT115 GDSC1; GDSC2 3.917 5.8453 2.5151 3.6028
SW1116 GDSC1; GDSC2 4.1734 6.4008 2.4212 3.6376
LS123 GDSC1; GDSC2 4.2057 6.5207 2.3855 3.7843
SK-CO-1 GDSC1; GDSC2 4.2282 6.9544 2.1942 4.8764
SW48 GDSC1; GDSC2 4.2772 7.4198 2.0041 5.9139
SNU-C5 GDSC2 4.2831 7.3107 2.0605 5.5621
LS513 GDSC1; GDSC2 4.3314 8.3332 1.5996 8.2247
CCK-81 GDSC1; GDSC2 4.4391 7.7158 1.9718 5.7646
KM12 GDSC1; GDSC2 4.4398 5.9453 2.7831 1.2243
HCT 15 GDSC1; GDSC2 4.4886 6.4349 2.5966 2.1027
HT-55 GDSC2 4.8235 6.9062 2.5724 1.7686
DiFi GDSC2 4.8299 9.9599 1.1601 9.6722
LoVo GDSC1; GDSC2 4.855 7.9842 2.1107 4.1722
RCM-1 [Human ESC] GDSC1; GDSC2 4.8844 7.5044 2.3446 2.8464
NCI-H508 GDSC1; GDSC2 4.8959 10.2117 1.0842 9.9558
SW948 GDSC1; GDSC2 4.9281 6.523 2.7801 0.7536
HCT 116 GDSC1; GDSC2 4.971 9.4155 1.5155 7.3481
SNU-175 GDSC2 5.0231 10.7677 0.9037 10.6803
LS411N GDSC1; GDSC2 5.1533 6.7471 2.7906 0.5588
MDST8 GDSC1; GDSC2 5.1655 6.8753 2.747 0.6959
LS180 GDSC1; GDSC2 5.2078 6.9719 2.728 0.7322
SW1417 GDSC1; GDSC2 5.2294 7.6255 2.4751 1.7487
SNU-1040 GDSC2 5.2599 6.6593 2.8655 0.2967
C2BBe1 GDSC1; GDSC2 5.3054 7.1793 2.6901 0.7949
SW837 GDSC1; GDSC2 5.3112 7.9421 2.3834 2.0812
SW620 GDSC1; GDSC2 5.3423 7.1464 2.7184 0.6728
SNU-81 GDSC2 5.3465 6.6624 2.8967 0.2004
CaR-1 GDSC1; GDSC2 5.3519 9.9001 1.5314 6.5307
HT-29 GDSC1; GDSC2 5.3778 6.469 2.9737 0.0785
GP5d GDSC1; GDSC2 5.3957 7.0614 2.7723 0.4764
LS1034 GDSC1; GDSC2 5.4078 6.9165 2.8297 0.3215
COLO205 GDSC1; GDSC2 5.4233 9.8151 1.6146 5.9437
SNU-283 GDSC2 5.4347 6.9845 2.8156 0.3454
CL-11 GDSC1; GDSC2 5.4505 9.5921 1.733 5.2498
SW1463 GDSC1; GDSC2 5.6566 7.4886 2.719 0.4921
T84 GDSC1; GDSC2 5.6781 7.6089 2.6832 0.5821
RKO GDSC1; GDSC2 5.6966 7.4735 2.7402 0.418
SNU-61 GDSC1; GDSC2 5.7423 7.4202 2.7767 0.3155
NCI-H716 GDSC1; GDSC2 5.7912 7.9436 2.6043 0.7576
COLO 320HSR GDSC1; GDSC2 5.8714 7.3881 2.8349 0.1697
SNU-C1 GDSC1; GDSC2 5.8837 7.7374 2.7171 0.3956
CW-2 GDSC1; GDSC2 6.007 8.0942 2.6358 0.5465
SW626 GDSC1; GDSC2 6.0973 8.2211 2.625 0.5342
COLO 678 GDSC1; GDSC2 6.3159 8.3302 2.6691 0.3434
SNU-C2B GDSC1; GDSC2 6.4918 8.81 2.5648 0.5104
HCC2998 GDSC1; GDSC2 6.508 8.297 2.7495 0.1611
SNU-407 GDSC2 7.2919 19.1991 -1.6015 17.3035
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 5.9712 7.7201 2.756 0.2814
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-4 GDSC1; GDSC2 2.3053 4.9057 1.5791 14.3902
Hep 3B2.1-7 GDSC2 3.3941 6.7748 1.6552 10.3221
JHH-7 GDSC1; GDSC2 3.9647 6.148 2.4021 4.1988
Huh-7 GDSC1; GDSC2 4.069 5.9051 2.5872 2.8755
JHH-1 GDSC1; GDSC2 4.3946 5.9649 2.751 1.4432
SNU-449 GDSC1; GDSC2 4.5763 6.7771 2.4938 2.527
HLE GDSC1; GDSC2 4.8102 7.497 2.3055 3.1816
JHH-6 GDSC1; GDSC2 4.8998 5.7761 3.0417 0.0759
Hep-G2/C3A GDSC1; GDSC2 5.1428 6.3422 2.9339 0.1916
HuH-1 GDSC1; GDSC2 5.2287 6.7907 2.8053 0.4721
SNU-423 GDSC2 5.2436 11.4892 0.7076 11.2966
SNU-398 GDSC2 5.3003 16.154 -1.5292 21.1887
JHH-2 GDSC1; GDSC2 5.5377 7.3764 2.7128 0.5745
SK-HEP-1 GDSC1; GDSC2 5.5929 6.957 2.8837 0.1586
SNU-387 GDSC1; GDSC2 5.6988 8.1306 2.492 1.2262
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 186 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1299 GDSC1; GDSC2 2.177 11.6675 -1.8396 30.8802
NCI-H526 GDSC1; GDSC2 3.1227 13.0758 -1.7221 27.5387
NCI-H2810 GDSC1; GDSC2 3.1238 4.9329 2.3459 6.7807
NCI-H2405 GDSC1; GDSC2 3.5133 5.1167 2.5786 4.1786
RERF-LC-MS GDSC1; GDSC2 3.5323 4.5998 2.8487 2.4371
NCI-H290 GDSC1; GDSC2 3.6838 5.4951 2.5202 4.1162
NCI-H1975 GDSC2 3.7842 6.9024 1.9009 7.7305
NCI-H1993 GDSC1; GDSC2 3.8711 6.8481 1.993 6.9404
NCI-H510A GDSC1; GDSC2 3.9217 7.6571 1.6317 9.0456
A-549 GDSC1; GDSC2 3.941 6.0107 2.4519 3.9475
IST-SL1 GDSC1; GDSC2 3.9448 8.7585 1.1037 12.1607
NCI-H1341 GDSC1; GDSC2 4.0052 6.644 2.1901 5.4047
NCI-H1792 GDSC1; GDSC2 4.1336 6.0194 2.5747 2.8263
SK-MES-1 GDSC1; GDSC2 4.1463 6.4645 2.3732 3.9904
SBC-5 GDSC1; GDSC2 4.2543 5.5841 2.8408 1.179
NCI-H2122 GDSC1; GDSC2 4.2705 7.7832 1.8238 7.0394
NCI-H2722 GDSC1; GDSC2 4.3863 6.5077 2.5044 2.778
NCI-H1755 GDSC1; GDSC2 4.3919 6.7775 2.3836 3.4552
NCI-H292 GDSC1; GDSC2 4.4439 6.6851 2.4579 2.941
NCI-H1048 GDSC1; GDSC2 4.4709 6.206 2.6874 1.6626
NCI-H1781 GDSC2 4.4748 6.737 2.4527 2.9179
SK-LU-1 GDSC1; GDSC2 4.4752 6.385 2.6112 2.0525
HCC827 GDSC1; GDSC2 4.4774 8.3167 1.7096 7.2679
NCI-H2171 GDSC2 4.4815 6.8263 2.4159 3.1127
BEN GDSC1; GDSC2 4.5114 5.3551 3.0472 0.1702
NCI-H2804 GDSC1; GDSC2 4.5131 7.745 2.0069 5.4254
NCI-H209 GDSC1; GDSC2 4.5426 6.6622 2.5259 2.4059
NCI-H2023 GDSC1; GDSC2 4.5719 8.5468 1.6635 7.3373
NCI-H1648 GDSC1; GDSC2 4.6206 6.5223 2.6305 1.7485
HARA [Human squamous cell lung carcinoma] GDSC2 4.6813 9.848 1.1106 10.3177
NCI-H727 GDSC1; GDSC2 4.6824 6.8224 2.5333 2.1601
NCI-H2369 GDSC2 4.709 10.8552 0.6394 12.8706
NCI-H2803 GDSC1; GDSC2 4.7273 6.9467 2.5034 2.2514
CAL-12T GDSC1; GDSC2 4.7512 10.6097 0.7896 11.9544
NCI-H82 GDSC1; GDSC2 4.7554 7.3164 2.355 2.9992
NCI-H226 GDSC1; GDSC2 4.7584 6.1189 2.863 0.5825
NCI-H2196 GDSC2 4.7591 6.5171 2.7036 1.2326
DMS 273 GDSC1; GDSC2 4.7787 7.5787 2.2502 3.537
LCLC-103H GDSC1; GDSC2 4.8177 7.6228 2.2532 3.4562
HCC78 GDSC1; GDSC2 4.8189 6.6263 2.6877 1.2397
NCI-H64 GDSC1; GDSC2 4.8296 6.0457 2.9204 0.353
NCI-H345 GDSC1; GDSC2 4.8472 5.7478 3.0329 0.0984
NCI-H441 GDSC1; GDSC2 4.8561 7.2461 2.4427 2.3834
NCI-H2595 GDSC1; GDSC2 4.8632 9.3062 1.4962 7.7031
NCI-H1703 GDSC1; GDSC2 4.8761 6.6433 2.7082 1.0915
NCI-H2029 GDSC1; GDSC2 4.9031 6.1138 2.9246 0.3051
IA-LM GDSC2 4.9068 6.781 2.6666 1.2407
NCI-H2227 GDSC1; GDSC2 4.9253 6.5724 2.7594 0.8375
Lu-135 GDSC1; GDSC2 4.9282 6.8556 2.6463 1.3082
NCI-H524 GDSC1; GDSC2 4.9321 7.1094 2.542 1.7874
NCI-H1155 GDSC1; GDSC2 4.9339 7.3831 2.4252 2.365
UMC-11 GDSC1; GDSC2 4.9471 6.4402 2.8205 0.5971
COR-L303 GDSC2 4.9504 6.254 2.8919 0.3709
A-427 GDSC1; GDSC2 4.9654 7.8945 2.2165 3.4195
NCI-H2066 GDSC2 4.9684 6.7094 2.7246 0.9379
NCI-H460 GDSC1; GDSC2 4.9785 6.4138 2.8438 0.4996
NCI-H2030 GDSC1; GDSC2 4.979 7.3252 2.4742 2.059
NCI-H2141 GDSC1; GDSC2 4.9912 6.4111 2.8501 0.4722
Lu-134-A GDSC1; GDSC2 5.0106 7.8212 2.2749 3.0374
KNS-62 GDSC2 5.0165 8.7295 1.866 5.2824
NCI-H1573 GDSC1; GDSC2 5.0829 7.2442 2.5613 1.5235
NCI-H720 GDSC1 5.0861 6.5451 2.8387 0.563
NCI-H1436 GDSC1; GDSC2 5.1167 6.4148 2.8985 0.2775
NCI-H1435 GDSC1; GDSC2 5.1337 6.9447 2.7061 0.8707
COR-L279 GDSC1; GDSC2 5.1425 6.4402 2.8992 0.2656
NCI-H196 GDSC1; GDSC2 5.1558 6.6534 2.8268 0.4489
COR-L321 GDSC1; GDSC2 5.1729 6.7857 2.7842 0.5691
LCLC-97TM1 GDSC1; GDSC2 5.1777 10.5064 1.1337 9.1119
NCI-H847 GDSC1 5.1979 6.7229 2.818 0.5627
NCI-H1092 GDSC1; GDSC2 5.2014 6.873 2.7631 0.6197
NCI-H596 GDSC1; GDSC2 5.236 8.2519 2.2101 3.0487
NCI-H810 GDSC1; GDSC2 5.2444 6.8021 2.8074 0.4575
EMC-BAC-2 GDSC2 5.2549 7.7161 2.45 1.8419
HOP-92 GDSC1; GDSC2 5.2716 10.5153 1.1914 8.6006
CPC-N GDSC1; GDSC2 5.2922 10.4688 1.2269 8.3625
NCI-H187 GDSC1 5.2932 6.484 2.9392 0.1761
NCI-H1304 GDSC1 5.2968 6.6443 2.8847 0.3003
COR-L105 GDSC1; GDSC2 5.2977 7.4576 2.5768 1.2403
NCI-H2085 GDSC1; GDSC2 5.3056 11.8267 0.5877 11.7969
COR-L23 GDSC1; GDSC2 5.3177 6.5919 2.9108 0.1834
Lu-139 GDSC1; GDSC2 5.3228 6.9355 2.7895 0.4671
Lu-165 GDSC1; GDSC2 5.347 6.5937 2.9207 0.1582
NCI-H146 GDSC1; GDSC2 5.3554 7.0367 2.7652 0.5204
NCI-H1694 GDSC1; GDSC2 5.3649 6.6579 2.905 0.1806
NCI-H522 GDSC2 5.3671 7.6707 2.5232 1.3984
PC-14 GDSC1; GDSC2 5.3847 7.2893 2.6818 0.7703
NCI-H2172 GDSC1; GDSC2 5.3989 6.8778 2.8402 0.3018
NCI-H2110 GDSC1; GDSC2 5.4001 7.8554 2.4636 1.6226
NCI-H2869 GDSC1; GDSC2 5.4074 7.5232 2.6007 1.0491
HCC44 GDSC1; GDSC2 5.4109 7.3079 2.6859 0.7383
NCI-H2444 GDSC2 5.424 6.6237 2.9377 0.1154
NCI-H513 GDSC2 5.4358 14.3558 -0.5479 16.9694
NCI-H1915 GDSC1; GDSC2 5.4591 7.3446 2.6923 0.6856
NCI-H2087 GDSC1; GDSC2 5.4832 7.3222 2.7107 0.6122
NCI-H2009 GDSC2 5.4892 7.7458 2.5496 1.179
NCI-H1581 GDSC1; GDSC2 5.5 6.8672 2.8813 0.1858
DMS 79 GDSC1; GDSC2 5.5071 7.1212 2.7942 0.3672
NCI-H1563 GDSC1; GDSC2 5.525 6.8152 2.908 0.1368
NCI-H2228 GDSC1; GDSC2 5.5389 7.6278 2.6179 0.8841
EPLC-272H GDSC1; GDSC2 5.5489 7.5613 2.6477 0.7744
SHP-77 GDSC1; GDSC2 5.5557 7.0079 2.8527 0.2221
COR-L95 GDSC1; GDSC2 5.5631 6.9032 2.8915 0.1532
NCI-H2818 GDSC1; GDSC2 5.5701 7.4233 2.7085 0.5692
COR-L88 GDSC1; GDSC2 5.5781 6.9686 2.8744 0.1772
LOU-NH91 GDSC2 5.6006 7.3089 2.7626 0.4055
DMS 53 GDSC2 5.6038 7.7879 2.5841 0.9571
NCI-H2135 GDSC1; GDSC2 5.6167 7.1635 2.8206 0.2662
NCI-H1876 GDSC1; GDSC2 5.6226 7.3485 2.7568 0.4104
NCI-H748 GDSC2 5.624 7.7135 2.6214 0.8124
DMS 114 GDSC1; GDSC2 5.6428 7.1898 2.821 0.2568
PaCa-3 GDSC1; GDSC2 5.6599 7.7807 2.611 0.8234
NCI-H1838 GDSC1; GDSC2 5.6715 7.5352 2.7078 0.5172
ChaGo-K-1 GDSC1; GDSC2 5.6797 7.4243 2.7515 0.3988
NCI-H1693 GDSC1; GDSC2 5.6817 9.7137 1.8124 4.4715
Calu-6 GDSC1; GDSC2 5.7009 13.8944 -0.137 14.5321
NCI-H1836 GDSC1; GDSC2 5.7028 7.2298 2.829 0.2232
SW1573 GDSC1; GDSC2 5.705 9.8659 1.7578 4.724
SBC-1 GDSC1; GDSC2 5.7136 7.7615 2.6407 0.6925
NCI-H1793 GDSC1; GDSC2 5.7186 7.4408 2.7604 0.3612
NCI-H1105 GDSC1; GDSC2 5.7219 7.2736 2.8207 0.233
LXF 289 GDSC1; GDSC2 5.7228 10.2512 1.5946 5.5643
HCC33 GDSC2 5.7246 7.3023 2.8117 0.2494
NCI-H2731 GDSC1; GDSC2 5.7303 8.5868 2.3227 1.8998
NCI-H838 GDSC1; GDSC2 5.743 7.1529 2.8698 0.1463
NCI-H2081 GDSC1; GDSC2 5.7552 7.4817 2.7597 0.3486
Calu-3 GDSC1; GDSC2 5.7765 7.5122 2.7569 0.3469
NCI-H835 GDSC1; GDSC2 5.7875 8.085 2.5488 0.9486
VMRC-LCD GDSC1; GDSC2 5.7967 7.5636 2.7462 0.3635
NCI-H1963 GDSC1; GDSC2 5.8039 7.4547 2.7875 0.2722
NCI-H2591 GDSC1; GDSC2 5.8054 8.6659 2.3264 1.8071
NCI-H446 GDSC1; GDSC2 5.8116 7.3279 2.8343 0.1853
NCI-H1568 GDSC1; GDSC2 5.8247 7.4914 2.7823 0.2759
NCI-H1688 GDSC1; GDSC2 5.8517 7.4415 2.8095 0.2168
HOP-62 GDSC2 5.8625 16.4874 -1.2824 19.0201
NCI-H2347 GDSC1; GDSC2 5.8716 8.1148 2.5731 0.8101
LK-2 GDSC1; GDSC2 5.9014 7.6121 2.7682 0.2794
Lu-65 GDSC1; GDSC2 5.9018 7.5045 2.8058 0.21
NCI-H1734 GDSC1; GDSC2 5.9056 7.6585 2.7535 0.3079
NCI-H2461 GDSC2 5.9083 8.6144 2.3951 1.4272
NCI-H1869 GDSC1 5.9195 7.716 2.7383 0.4177
Ms-1 GDSC1; GDSC2 5.9309 7.631 2.7724 0.2621
COR-L311 GDSC2 5.9481 7.8445 2.7033 0.4036
Lu-99A GDSC1; GDSC2 5.9542 8.3303 2.5259 0.912
NCI-H3255 GDSC1; GDSC2 5.9549 7.7092 2.7539 0.2909
NCI-H2170 GDSC1; GDSC2 5.9712 7.6858 2.768 0.2584
RERF-LC-KJ GDSC1; GDSC2 5.9761 7.5816 2.8058 0.1914
NCI-H1651 GDSC1; GDSC2 5.9767 7.8988 2.6948 0.4122
NCI-H358 GDSC1; GDSC2 5.9809 8.5842 2.4395 1.1977
NCI-H211 GDSC1; GDSC2 5.9825 7.7909 2.7354 0.3196
SBC-3 GDSC1; GDSC2 5.9884 7.6597 2.7833 0.2259
NCI-H2291 GDSC1; GDSC2 5.9973 7.788 2.7419 0.3013
NCI-H520 GDSC1; GDSC2 6.0144 7.7275 2.7692 0.2438
NCI-H250 GDSC2 6.0246 7.8414 2.7332 0.3099
NCI-H1437 GDSC1; GDSC2 6.041 8.1779 2.6186 0.5784
NCI-H2342 GDSC1; GDSC2 6.0518 7.7466 2.7762 0.2216
NCI-H23 GDSC1; GDSC2 6.0758 8.0088 2.6931 0.3776
ABC-1 GDSC1; GDSC2 6.0804 7.852 2.75 0.2601
NCI-H1650 GDSC1; GDSC2 6.1088 8.2597 2.6154 0.5541
EBC-1 GDSC1; GDSC2 6.1147 7.8819 2.752 0.2468
LC-1/sq GDSC2 6.1208 8.3378 2.5915 0.613
LB647-SCLC GDSC1; GDSC2 6.126 7.8122 2.7801 0.1968
NCI-H1355 GDSC1; GDSC2 6.1424 8.3489 2.596 0.5899
HCC15 GDSC2 6.155 8.1027 2.6896 0.3567
NCI-H740 GDSC2 6.1588 8.303 2.6192 0.521
NCI-H2795 GDSC1; GDSC2 6.1696 8.1306 2.6851 0.3611
NCI-H69 GDSC1; GDSC2 6.1703 7.9143 2.7609 0.2172
COLO 668 GDSC1; GDSC2 6.1773 7.8064 2.8002 0.1565
RERF-LC-Sq1 GDSC2 6.184 8.6407 2.5045 0.8354
NCI-H841 GDSC2 6.2021 7.8849 2.7822 0.1768
NCI-H1623 GDSC1; GDSC2 6.2546 8.0827 2.7331 0.2424
SW1271 GDSC1; GDSC2 6.2642 8.0807 2.7372 0.2329
NCI-H2373 GDSC1; GDSC2 6.27 8.0118 2.7629 0.1907
NCI-H3122 GDSC1; GDSC2 6.2828 7.9676 2.7824 0.1602
NCI-H647 GDSC1; GDSC2 6.2959 8.4922 2.6039 0.4993
LC-2/ad GDSC1; GDSC2 6.3112 8.1348 2.7354 0.2242
IST-SL2 GDSC1; GDSC2 6.3338 8.211 2.7172 0.2488
NCI-H1944 GDSC2 6.3674 8.3446 2.6831 0.3011
NCI-H661 GDSC1; GDSC2 6.4337 8.1973 2.7573 0.1651
EKVX GDSC2 6.4382 9.0728 2.447 0.8627
COR-L32 GDSC2 6.458 8.2287 2.7551 0.1635
NCI-H1666 GDSC1; GDSC2 6.5682 8.3098 2.7659 0.1313
NCI-H1770 GDSC1; GDSC2 6.6057 14.2924 0.2722 10.803
NCI-H650 GDSC1; GDSC2 6.6263 16.6074 -0.8097 15.5765
HCC366 GDSC2 6.7066 8.3908 2.786 0.0924
EMC-BAC-1 GDSC2 7.526 9.893 2.5644 0.2161
NCI-H322M GDSC1; GDSC2 7.9739 18.6908 -0.9181 13.5661
⏷ Show the Full List of 186 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 6.1948 8.1056 2.7033 0.315
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OE33 GDSC1; GDSC2 3.5494 5.2941 2.5184 4.4633
OE19 GDSC1; GDSC2 3.973 6.6524 2.1631 5.6445
KYSE-140 GDSC1; GDSC2 4.5814 8.4215 1.73 6.9236
TE-1 GDSC1; GDSC2 4.8713 7.1654 2.4861 2.1409
EC-GI-10 GDSC1; GDSC2 5.1675 6.9747 2.7093 0.832
KYSE-150 GDSC1; GDSC2 5.2215 10.8642 0.9922 9.8033
OE21 GDSC2 5.5409 7.5231 2.6589 0.7423
TE-5 GDSC1; GDSC2 5.548 7.1015 2.8168 0.2981
TE-8 GDSC1; GDSC2 5.5552 7.9054 2.5162 1.2541
TE-11 GDSC1; GDSC2 5.5736 6.9831 2.8678 0.1896
TE-6 GDSC1; GDSC2 5.5831 7.2847 2.7645 0.4084
TE-9 GDSC1; GDSC2 5.6073 7.0755 2.8479 0.2158
KYSE-450 GDSC1; GDSC2 5.6359 15.1096 -0.7724 17.4818
KYSE-180 GDSC1; GDSC2 5.8007 12.0056 0.8312 9.508
T.T GDSC2 5.8303 7.6874 2.7146 0.4252
KYSE-510 GDSC1; GDSC2 5.8616 7.7021 2.7214 0.3958
COLO 680N GDSC1; GDSC2 5.8657 7.2397 2.8832 0.1065
KYSE-520 GDSC1; GDSC2 5.8766 8.5037 2.4246 1.3387
TE-4 GDSC2 5.9423 7.7638 2.7299 0.3453
KYSE-270 GDSC1; GDSC2 5.9876 8.2166 2.5827 0.7101
TE-15 GDSC1; GDSC2 6.0371 8.1602 2.6235 0.5668
TE-10 GDSC1; GDSC2 6.059 7.8115 2.7563 0.2547
KYSE-70 GDSC1; GDSC2 6.2461 7.857 2.807 0.135
KYSE-410 GDSC1; GDSC2 7.2494 17.683 -0.9085 14.7977
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OAW42 GDSC2 4.3596 6.5159 2.4846 2.9359
OVCAR-8 GDSC1; GDSC2 4.5387 7.2998 2.2324 4.0576
OV56 GDSC1; GDSC2 4.6086 6.198 2.7619 1.1326
JHOS-2 GDSC1; GDSC2 4.6183 6.7125 2.5462 2.1847
TYK-nu GDSC1; GDSC2 4.6347 6.8591 2.4905 2.4553
TOV-21G GDSC2 4.641 12.8594 -0.397 18.1849
JHOS-4 GDSC1; GDSC2 4.7695 6.8959 2.5484 1.9634
OVISE GDSC1; GDSC2 4.9695 8.4003 1.9891 4.6715
OC 314 GDSC1; GDSC2 4.9944 8.7212 1.8562 5.3784
SK-OV-3 GDSC1; GDSC2 5.1228 6.973 2.69 0.9412
OVTOKO GDSC1; GDSC2 5.294 7.5404 2.5415 1.3921
DOV13 GDSC1; GDSC2 5.3238 7.1995 2.6903 0.784
EFO-21 GDSC1; GDSC2 5.3282 6.8696 2.8159 0.3921
ES-2 GDSC1; GDSC2 5.4753 6.9776 2.8335 0.2881
IGROV-1 GDSC1; GDSC2 5.5142 9.7171 1.7139 5.2647
Caov-3 GDSC2 5.5694 6.8996 2.8949 0.1466
OVKATE GDSC1; GDSC2 5.5901 7.2197 2.7906 0.3417
FU-OV-1 GDSC1; GDSC2 5.6222 13.6135 -0.0558 14.3206
OVK18 GDSC2 5.6687 7.3222 2.7838 0.3268
OVCAR-5 GDSC1; GDSC2 5.8021 7.2895 2.8441 0.1719
EFO-27 GDSC1; GDSC2 5.8081 7.8705 2.6387 0.6438
Caov-4 GDSC2 5.8224 8.4149 2.4352 1.3429
Kuramochi GDSC1; GDSC2 5.8741 8.1858 2.5471 0.8944
OV-90 GDSC2 5.8764 7.9311 2.6438 0.592
OVCAR-4 GDSC1; GDSC2 5.9158 7.7946 2.7089 0.4035
TOV-112D GDSC1; GDSC2 6.0505 8.1429 2.6351 0.5295
OVCAR-3 GDSC1; GDSC2 6.0861 7.8092 2.7669 0.2285
A2780 GDSC1; GDSC2 6.1947 7.8119 2.8044 0.1476
OAW28 GDSC1; GDSC2 6.2085 10.304 1.8417 3.5859
RMG-I GDSC1; GDSC2 6.6361 8.666 2.6689 0.2531
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PSN1 GDSC1; GDSC2 4.0724 5.7591 2.6575 2.4601
MIA PaCa-2 GDSC1; GDSC2 4.279 5.5596 2.8641 1.035
Panc 02.03 GDSC2 4.3436 6.8822 2.3042 4.0075
PL4 GDSC1; GDSC2 4.534 6.4266 2.6254 1.8933
HPAC GDSC1; GDSC2 4.6375 10.526 0.7488 12.4457
HuP-T4 GDSC1; GDSC2 5.0935 7.1888 2.5893 1.3874
SUIT-2 GDSC1; GDSC2 5.1774 6.5955 2.8566 0.3555
YAPC GDSC1; GDSC2 5.2401 6.4429 2.9343 0.1628
KP-2 GDSC1; GDSC2 5.2621 9.6854 1.5751 6.4736
PaTu 8988t GDSC1; GDSC2 5.3288 13.0197 0.0267 14.5713
KP-3 GDSC1; GDSC2 5.3489 8.2122 2.2879 2.503
SU.86.86 GDSC1; GDSC2 5.3702 6.5514 2.9434 0.1182
KP-1N GDSC1; GDSC2 5.3822 7.9536 2.4142 1.8632
Hs 766T GDSC2 5.3992 7.099 2.7597 0.5123
PaTu 8902 GDSC1; GDSC2 5.4543 6.6057 2.9542 0.0891
BxPC-3 GDSC1; GDSC2 5.49 11.0005 1.1042 8.6489
HPAF-II GDSC1; GDSC2 5.525 7.9358 2.4901 1.3872
QGP-1 GDSC1; GDSC2 5.6726 7.8443 2.592 0.8794
KP-4 GDSC1; GDSC2 5.7197 7.3862 2.7803 0.3157
Capan-1 GDSC1; GDSC2 5.7712 7.5069 2.7568 0.3491
HuP-T3 GDSC1; GDSC2 5.7793 7.5286 2.7521 0.3567
Panc 10.05 GDSC1; GDSC2 5.8084 8.2436 2.4964 1.1213
DAN-G GDSC1; GDSC2 5.831 7.5741 2.7554 0.3299
Panc 03.27 GDSC1; GDSC2 5.9048 7.4889 2.8122 0.1984
AsPC-1 GDSC1; GDSC2 5.949 8.7129 2.3744 1.4737
Capan-2 GDSC1; GDSC2 5.9795 7.9051 2.6936 0.4139
Panc 04.03 GDSC1; GDSC2 6.0116 7.4213 2.8724 0.0966
MZ-PC-1 GDSC1; GDSC2 6.166 8.3781 2.5947 0.5821
Panc 08.13 GDSC1; GDSC2 6.2294 12.008 1.0962 7.35
SW1990 GDSC1; GDSC2 6.5029 8.3973 2.7136 0.2135
CFPAC-1 GDSC1; GDSC2 8.7782 21.9787 -1.9458 15.9656
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC1; GDSC2 4.2162 6.9392 2.1933 4.9239
NCI-H2452 GDSC1; GDSC2 4.3464 7.6915 1.9208 6.2869
IST-Mes1 GDSC1; GDSC2 5.6541 10.7001 1.3478 7.0152
MPP 89 GDSC1; GDSC2 5.7349 7.7113 2.6682 0.597
NCI-H2052 GDSC1; GDSC2 5.7884 7.5854 2.7353 0.3926
MSTO-211H GDSC1; GDSC2 6.1482 7.7047 2.8244 0.1304
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC1; GDSC2 2.7224 7.2406 0.843 17.3141
PC-3 GDSC1; GDSC2 4.2964 6.3358 2.5289 2.7949
VCaP GDSC1; GDSC2 4.642 10.472 0.7785 12.2719
NCI-H660 GDSC2 4.8751 6.3541 2.8227 0.6409
22Rv1 GDSC1; GDSC2 6.5502 8.3317 2.7524 0.1504
LNCaP clone FGC GDSC1; GDSC2 9.1376 27.9964 -4.5695 22.6603
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 5.7349 7.9901 2.5627 0.9374
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-7951 GDSC1; GDSC2 3.5429 6.7662 1.7803 9.1227
SK-MEL-2 GDSC1; GDSC2 3.6757 8.9168 0.8136 14.5681
COLO 829 GDSC1; GDSC2 3.746 9.2629 0.697 15.0282
A101D GDSC1; GDSC2 3.9428 6.5995 2.1673 5.6889
HT-144 GDSC1; GDSC2 4.0944 6.3928 2.3728 4.0997
COLO 792 GDSC1; GDSC2 4.1123 6.9894 2.0978 5.7285
WM35 GDSC1; GDSC2 4.203 6.1186 2.5718 2.7159
SK-MEL-28 GDSC1; GDSC2 4.4166 5.4892 2.9583 0.4944
WM278 GDSC1; GDSC2 4.4657 8.6209 1.5545 8.217
A-375 GDSC1; GDSC2 4.5643 7.8357 1.9974 5.379
DJM-1 GDSC1; GDSC2 4.6241 6.9277 2.4538 2.6693
SK-MEL-31 GDSC1; GDSC2 4.7062 6.3927 2.7291 1.1746
SK-MEL-30 GDSC1; GDSC2 4.7113 5.8705 2.9376 0.3672
A2058 GDSC1; GDSC2 4.7355 5.9642 2.9124 0.4311
LB373-MEL-D GDSC2 4.7541 6.1052 2.8665 0.5735
CP50-MEL-B GDSC1; GDSC2 4.7905 6.5648 2.6992 1.2185
CP66-MEL GDSC2 4.8275 6.1987 2.862 0.5373
WM793 GDSC1; GDSC2 4.8678 8.9959 1.6467 6.8231
VMRC-MELG GDSC1; GDSC2 4.9233 6.2055 2.899 0.3649
IGR-1 GDSC1; GDSC2 4.9614 10.1156 1.1752 9.3332
WM115 GDSC1; GDSC2 4.9873 9.0393 1.7034 6.2632
IGR-37 GDSC1; GDSC2 5.022 6.12 2.9673 0.1643
LB2518-MEL GDSC1; GDSC2 5.0423 6.4884 2.8421 0.4668
Hs 940.T GDSC2 5.0431 6.5241 2.829 0.5068
SK-MEL-5 GDSC2 5.1012 6.4725 2.8716 0.3518
GAK GDSC1; GDSC2 5.1272 7.1449 2.6233 1.2076
WM1552C GDSC1; GDSC2 5.1354 7.0275 2.6741 0.9928
COLO 800 GDSC1; GDSC2 5.1613 6.954 2.7147 0.8169
IST-MEL1 GDSC1; GDSC2 5.1893 7.3649 2.5632 1.4033
MZ-MEL-7 GDSC1; GDSC2 5.2101 7.1919 2.6428 1.0521
WT2-iPS GDSC1; GDSC2 5.2881 6.9907 2.7548 0.5917
LOX-IMVI GDSC1; GDSC2 5.2968 6.7577 2.8442 0.3337
UACC-62 GDSC1; GDSC2 5.3064 8.2936 2.2302 2.8479
CHL-1 GDSC1; GDSC2 5.3459 7.3841 2.628 0.9952
IPC-298 GDSC1; GDSC2 5.3773 6.7435 2.8796 0.2248
SK-MEL-1 GDSC1; GDSC2 5.3974 10.1278 1.454 6.899
SK-MEL-24 GDSC1; GDSC2 5.4331 7.1346 2.7602 0.4928
G-mel GDSC1; GDSC2 5.454 7.1769 2.753 0.5024
G-361 GDSC1; GDSC2 5.4639 6.7973 2.8925 0.1759
COLO 783 GDSC2 5.4857 6.8269 2.8901 0.1744
Mel JuSo GDSC1; GDSC2 5.5408 7.1158 2.809 0.3184
M14 GDSC1 5.6453 7.2866 2.7877 0.4074
RVH-421 GDSC1; GDSC2 5.6485 7.1977 2.8203 0.2564
SK-MEL-3 GDSC1; GDSC2 5.6567 7.0375 2.8787 0.1517
451Lu GDSC1; GDSC2 5.6922 7.3955 2.7666 0.3573
MMAc-SF GDSC1; GDSC2 5.71 7.064 2.8884 0.127
A-431 GDSC1; GDSC2 5.7784 7.3935 2.7995 0.2564
SH-4 GDSC1; GDSC2 5.7965 7.4936 2.771 0.3085
COLO 679 GDSC1; GDSC2 5.8144 7.2708 2.8548 0.153
Mel Ho GDSC1; GDSC2 5.892 7.2394 2.8922 0.0924
Hs 938.T GDSC2 5.922 7.3041 2.8809 0.1003
MeWo GDSC1; GDSC2 6.035 8.6634 2.4324 1.1823
A-388 GDSC1; GDSC2 6.3453 8.2857 2.6955 0.2842
MZ-MEL-2 GDSC1; GDSC2 6.4648 8.5114 2.6605 0.3147
HMV-II GDSC1; GDSC2 6.5764 8.7496 2.6181 0.3629
UACC-257 GDSC1; GDSC2 9.2436 23.0543 -2.1541 15.9162
EquiPSC Line K2 GDSC1; GDSC2 6.6973 8.734 2.6674 0.2407
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 5.6409 7.3343 2.7689 0.3725
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GCT GDSC1; GDSC2 3.5996 5.6546 2.3782 5.2151
VA-ES-BJ GDSC1; GDSC2 4.3166 8.0522 1.7257 7.5275
SW982 GDSC1; GDSC2 4.3718 8.5715 1.5123 8.6818
MES-SA GDSC2 4.5464 6.7496 2.4889 2.6005
SK-UT-1 GDSC1; GDSC2 4.605 7.3042 2.2713 3.7158
HT-1080 GDSC1; GDSC2 4.6593 7.1174 2.3888 2.9674
EW-8 GDSC1; GDSC2 4.686 6.3565 2.7342 1.1734
Rh30 GDSC1; GDSC2 5.1381 7.2089 2.6025 1.2853
SW872 GDSC1; GDSC2 5.1407 7.7572 2.3738 2.3475
SW684 GDSC1; GDSC2 5.2044 13.9161 -0.5 17.2886
RKN GDSC1; GDSC2 5.2724 6.5733 2.9007 0.2163
KYM-1 GDSC1; GDSC2 5.4851 7.0186 2.8226 0.3088
SK-LMS-1 GDSC2 5.6798 11.6918 0.901 9.373
G-401 GDSC1; GDSC2 5.7292 9.1786 2.0729 3.0724
MFH-ino GDSC1; GDSC2 5.7331 7.8573 2.6127 0.7697
Rh18 GDSC1 5.7857 7.0213 2.9286 0.0874
TE 441.T GDSC2 5.8003 7.1979 2.8746 0.1284
Rh41 GDSC1; GDSC2 5.9447 7.3965 2.8577 0.1241
RD GDSC1; GDSC2 6.1305 8.0917 2.6842 0.3771
G-402 GDSC1; GDSC2 6.232 15.5971 -0.5924 15.4547
A-204 GDSC1; GDSC2 6.9066 9.3769 2.5197 0.4559
Hs 633.T GDSC1; GDSC2 7.1735 15.2504 0.18 10.2397
STS-0421 GDSC1; GDSC2 7.1776 9.1119 2.7062 0.11
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1 GDSC1; GDSC2 4.1172 6.2949 2.4345 3.6834
SNU-16 GDSC1; GDSC2 4.1524 7.1515 2.0473 5.9469
NCI-N87 GDSC1; GDSC2 4.3005 6.9126 2.2619 4.3414
AGS GDSC1; GDSC2 4.4417 5.9967 2.7622 1.3274
MKN7 GDSC1; GDSC2 4.571 6.9461 2.4146 2.9693
MKN28 GDSC1; GDSC2 4.7614 8.4357 1.8421 5.8995
KATO III GDSC1; GDSC2 4.8382 6.9044 2.5807 1.7158
MKN45 GDSC1; GDSC2 4.9062 8.3315 1.9821 4.8229
SNU-5 GDSC1; GDSC2 4.9078 6.059 2.9462 0.2488
HSC-39 GDSC1; GDSC2 4.9636 7.0582 2.5796 1.5726
Hs 746.T GDSC1; GDSC2 5.0524 6.8001 2.7267 0.8585
SCH GDSC1; GDSC2 5.2379 6.6231 2.87 0.2958
ECC12 GDSC2 5.3077 6.4932 2.9412 0.1348
ECC10 GDSC1; GDSC2 5.3443 7.0665 2.7495 0.5744
GCIY GDSC1; GDSC2 5.4517 7.5495 2.6102 0.9778
NUGC-4 GDSC1; GDSC2 5.4636 7.2721 2.7215 0.5905
TMK-1 GDSC1; GDSC2 5.4703 8.5987 2.1857 2.8518
MKN1 GDSC1; GDSC2 5.526 6.8432 2.8989 0.1504
RF-48 GDSC1; GDSC2 5.575 7.7639 2.5808 0.9907
NUGC-3 GDSC1; GDSC2 5.6993 7.1947 2.8399 0.2045
23132/87 GDSC2 5.9182 15.2386 -0.6359 16.2936
Fu97 GDSC1; GDSC2 6.0099 7.454 2.8609 0.1095
OCUM-1 GDSC2 6.0768 8.3877 2.5553 0.7422
IM95 GDSC1; GDSC2 6.2072 8.1047 2.7082 0.3015
TGBC11TKB GDSC1; GDSC2 6.3231 7.9235 2.8112 0.1177
RERF-GC-1B GDSC1; GDSC2 6.3582 8.8758 2.4879 0.7849
SK-GT-2 GDSC2 6.52 8.9109 2.5393 0.563
HGC-27 GDSC1; GDSC2 7.9351 19.1067 -1.137 14.4775
SNG-M GDSC1; GDSC2 5.5094 7.5203 2.6466 0.8049
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHT-101 GDSC1; GDSC2 3.8497 7.3372 1.7354 8.5898
K5 GDSC1; GDSC2 4.0816 6.1613 2.4744 3.5174
KMH-2 GDSC1; GDSC2 4.2817 6.2816 2.5449 2.7302
FTC-133 GDSC1; GDSC2 4.4612 7.0573 2.2968 3.8291
TT2609-C02 GDSC1; GDSC2 4.5669 6.8456 2.4577 2.7384
B-CPAP GDSC1; GDSC2 4.6309 8.0557 1.9368 5.6029
IHH-4 GDSC1; GDSC2 4.6982 6.9924 2.4671 2.4846
CGTH-W-1 GDSC1; GDSC2 4.8131 7.4772 2.3161 3.1191
8505C GDSC2 4.8792 8.9034 1.6978 6.505
WRO GDSC1; GDSC2 4.9415 7.8163 2.2378 3.3417
CAL-62 GDSC1; GDSC2 5.0759 6.409 2.8847 0.3291
HTC-C3 GDSC1; GDSC2 5.1867 7.5354 2.4915 1.7272
TT GDSC1; GDSC2 5.2509 6.6962 2.8487 0.3426
8305C GDSC1; GDSC2 5.6163 7.2356 2.7949 0.3217
ASH-3 GDSC2 5.844 7.1462 2.9069 0.0838
ML-1 [Human leukemia] GDSC1; GDSC2 5.8962 7.5397 2.7916 0.2366
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-27 GDSC1; GDSC2 3.4836 5.7764 2.2267 6.4778
BICR 10 GDSC1 3.7623 5.4297 2.6086 4.2167
BB49-HNC GDSC1 3.8488 7.3293 1.7386 10.6136
HO-1-u-1 GDSC1; GDSC2 4.0247 6.0242 2.502 3.4685
PE/CA-PJ15 GDSC1; GDSC2 4.0394 5.7839 2.6252 2.7098
SCC-4 GDSC1; GDSC2 4.1076 7.1305 2.026 6.1775
LB771-HNC GDSC1; GDSC2 4.1141 5.8237 2.6535 2.4078
HO-1-N-1 GDSC1; GDSC2 4.4485 6.5814 2.5078 2.6549
KOSC-2 GDSC1; GDSC2 4.4551 9.4313 1.1524 10.603
Ca9-22 GDSC1; GDSC2 4.5811 6.1674 2.761 1.1671
HSC-4 GDSC1; GDSC2 4.617 8.0904 1.9114 5.78
HSC-3 GDSC1; GDSC2 4.8047 15.1858 -1.4241 21.9776
SAT [Human HNSCC] GDSC2 4.9547 17.0663 -2.2414 24.3878
SKN-3 GDSC2 5.1032 16.5317 -1.8635 22.814
PCI-38 GDSC1 5.1129 7.0051 2.6728 1.2677
BICR 22 GDSC2 5.1141 6.5564 2.8459 0.4161
PCI-15A GDSC1; GDSC2 5.2134 7.0772 2.6895 0.8695
PCI-30 GDSC2 5.2391 9.4366 1.6762 5.9491
HSC-2 GDSC1; GDSC2 5.2576 6.8012 2.813 0.4346
DOK GDSC1; GDSC2 5.3902 9.708 1.6437 5.861
NCI-H3118 GDSC2 5.4061 7.9668 2.4205 1.8081
Detroit 562 GDSC1; GDSC2 5.5082 10.5419 1.3306 7.3748
JHU-022 GDSC2 5.5146 8.4593 2.2684 2.3915
KON GDSC1; GDSC2 5.5316 7.3649 2.7146 0.5725
BHY GDSC1; GDSC2 5.5583 7.1184 2.8147 0.299
PCI-04B GDSC1; GDSC2 5.5645 7.4989 2.6779 0.6659
FaDu GDSC1; GDSC2 5.6079 7.0049 2.8726 0.1728
JHU-011 GDSC2 5.6365 7.8998 2.5549 1.0388
BICR 31 GDSC2 5.6534 7.606 2.6743 0.6246
BB30-HNC GDSC1; GDSC2 5.7608 7.7999 2.6457 0.6494
BICR 78 GDSC1; GDSC2 5.793 7.9078 2.6185 0.7141
CAL-33 GDSC1; GDSC2 5.8084 7.3458 2.827 0.1981
SCC-25 GDSC1; GDSC2 5.829 7.5538 2.7619 0.3167
OSC-19 GDSC2 5.8477 7.5927 2.7551 0.3246
UPCI-SCC-090 GDSC1; GDSC2 5.8726 7.681 2.7331 0.3643
SCC-9 GDSC1; GDSC2 5.8846 7.6463 2.75 0.3226
OSC-20 GDSC1; GDSC2 5.892 8.0632 2.601 0.7099
PCI-06A GDSC1; GDSC2 5.9653 7.9414 2.6751 0.4653
SAS GDSC1; GDSC2 6.125 7.8958 2.751 0.2459
SCC-15 GDSC1; GDSC2 6.1778 8.1225 2.6911 0.3457
JHU-029 GDSC1; GDSC2 6.3521 8.4282 2.6481 0.3762
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
639V GDSC1; GDSC2 3.6406 5.2064 2.6303 3.5355
HT-1197 GDSC1; GDSC2 3.9444 5.8518 2.5306 3.4635
SW1710 GDSC1; GDSC2 4.0698 6.4528 2.3274 4.4256
CAL-29 GDSC1; GDSC2 4.3612 8.7393 1.4229 9.2378
UM-UC-3 GDSC1; GDSC2 4.5209 6.4451 2.6101 1.9914
BFTC-905 GDSC1; GDSC2 4.5271 7.0039 2.362 3.3378
5637 GDSC1; GDSC2 4.6052 8.6727 1.6257 7.4891
647V GDSC1; GDSC2 4.7267 6.3701 2.7484 1.0678
KU-19-19 GDSC1; GDSC2 4.8057 8.509 1.8361 5.8481
RT-4 GDSC2 5.1609 6.9885 2.701 0.868
RT-112 GDSC1; GDSC2 5.1724 6.6206 2.8455 0.3875
TCCSUP GDSC1; GDSC2 5.2058 12.2619 0.308 13.4567
SW780 GDSC1; GDSC2 5.8229 7.3816 2.8198 0.2066
HT-1376 GDSC1; GDSC2 6.0858 8.255 2.608 0.5852
J82 GDSC1; GDSC2 6.192 8.2457 2.6526 0.4253
T24 GDSC1; GDSC2 6.4416 8.5475 2.6393 0.364
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB831-BLC GDSC1; GDSC2 3.7169 5.2767 2.6509 3.2286
PWR-1E GDSC2 4.1411 9.0033 1.1317 11.4911
ACC-OV7 GDSC1; GDSC2 4.1899 7.7598 1.7781 7.5006
HeLa GDSC2 4.1944 5.4938 2.848 1.2224
SKN GDSC2 4.2484 7.4618 1.964 6.2399
NEC8 GDSC2 4.4158 7.0651 2.2645 4.1016
C-4-I GDSC2 4.5135 7.8134 1.9747 5.6149
SKG-IIIa GDSC1; GDSC2 4.521 6.3113 2.6686 1.6897
SW954 GDSC1; GDSC2 4.6597 6.773 2.5424 2.1451
SiHa GDSC1; GDSC2 4.6921 5.9762 2.8895 0.5371
PA-1 GDSC1; GDSC2 4.7519 6.6787 2.6322 1.5737
SW756 GDSC2 4.8889 7.1228 2.5138 1.9794
OVMIU GDSC1; GDSC2 4.9142 7.2812 2.4589 2.2205
JEG-3 GDSC1; GDSC2 4.968 7.5383 2.376 2.5703
HEC-1 GDSC1; GDSC2 4.9889 6.7269 2.727 0.9105
SiSo GDSC2 4.9889 8.0761 2.1484 3.7534
DoTc2 4510 GDSC1; GDSC2 5.0931 7.0172 2.6589 1.0919
HT-3 GDSC1; GDSC2 5.1086 7.6281 2.4124 2.1981
PEO1 GDSC2 5.1294 13.4902 -0.3459 16.7734
OVCA420 GDSC2 5.1401 15.4483 -1.3007 20.7156
MS751 GDSC2 5.3058 6.9037 2.7945 0.4619
JAR GDSC1; GDSC2 5.3372 6.7639 2.8574 0.2861
NT2-D1 GDSC1; GDSC2 5.3393 7.2612 2.6731 0.8337
OMC-1 [Human cervical carcinoma] GDSC2 5.3733 7.0802 2.7563 0.537
KGN GDSC1; GDSC2 5.4674 7.7841 2.5244 1.2995
DSH1 GDSC1; GDSC2 5.5047 8.5032 2.2447 2.5178
HEY GDSC2 5.556 8.3484 2.3359 2.0277
NCC-IT GDSC2 5.5991 7.089 2.8402 0.2327
OV17R GDSC1; GDSC2 5.6166 7.4102 2.7319 0.4785
C-33 A GDSC1; GDSC2 5.6494 7.5111 2.7079 0.5284
BPH-1 GDSC1; GDSC2 5.6577 8.1574 2.4626 1.3784
SW962 GDSC1; GDSC2 5.6622 7.2788 2.7968 0.3005
TC-YIK GDSC1; GDSC2 5.7416 7.4824 2.7543 0.3665
CAL-39 GDSC1; GDSC2 5.8145 7.5996 2.7401 0.3707
UWB1.289 GDSC1; GDSC2 5.9991 8.2781 2.5644 0.7595
JHOS-3 GDSC1; GDSC2 6.0778 7.8021 2.7664 0.2316
OVCA433 GDSC1; GDSC2 6.187 8.0039 2.7359 0.2556
Ca Ski GDSC1; GDSC2 6.2099 8.6412 2.5149 0.788
ME-180 GDSC1; GDSC2 6.8166 9.033 2.6071 0.3119
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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