Details of the Drug

General Information of Drug (ID: DMJ7WRI)

Drug Name

GCC-1290K

Synonyms

GC-1290K; GC-2101; GCC-1290A; GCC-1290K (salt formulation, oral), Green Cross; Dopamine modulators (Parkinson's disease, oral), Kangwon University/Green Cross; (+)-3-hydroxymorphinan; 3-HM; 3-HM prodrugs (Parkinson's disease), Green Cross; 3-hydroxymorphinan prodrugs (Parkinson's disease), Green Cross

Indication

Disease Entry	ICD 11	Status	REF
Parkinson disease	8A00.0	Phase 1	[1]
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Structure

3D MOL

2D MOL

Cross-matching ID

PubChem CID: 46213529
TTD ID: D07HYR

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Protein kinase C (PRKC)	TTYVX59	NOUNIPROTAC	Modulator	[1]
Voltage-gated calcium channel (Cav)	TTCRJKY	NOUNIPROTAC	Modulator	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Inhibitory effect of glutamate release from rat cerebrocortical synaptosomes by dextromethorphan and its metabolite 3-hydroxymorphinan. Neurochem Int. 2009 Jul;54(8):526-34.