Details of the Drug

General Information of Drug (ID: DMJ9RN8)

Drug Name

SAR-339658

Synonyms

CHR-1103; GBR-500; TMC-2003; Integrin antibody (inflammation), Chromos; Integrin antibody (inflammation), Targeted Molecules Corp; Integrin antibody (multiple sclerosis), Chromos; Integrin antibody (multiple sclerosis), Glenmark; CD49b antagonist (inflammation/multiple sclerosis), Glenmark

Indication

Disease Entry	ICD 11	Status	REF
Inflammatory bowel disease	DD72	Phase 2	[1]

Drug Type

Antibody

Cross-matching ID

TTD ID: D0R9IH

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Integrin alpha-2/beta-1 (ITGA2/B1)	TTMSB0A	ITA2_HUMAN-ITB1_HUMAN	Not Available	[2]

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT01659138) Efficacy and Safety of SAR339658 in Patients With Moderate to Severe Ulcerative Colitis. U.S. National Institutes of Health.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2578).