Details of the Drug

General Information of Drug (ID: DMJAJSJ)

• Drug Name: Clobutinol
• Synonyms: Clobutinol hydrochloride; Silomat; Biotertussin; Petoxil; Pertoxil; Silom; 1215-83-4; UNII-N2U6799DZQ; Clobutinol HCl; KAT 256; EINECS 214-931-7; Clobutinol hydrochloride [JAN]; N2U6799DZQ; 2-(p-Chlorobenzyl)-3-dimethylaminomethyl-2-butanol hydrochloride; 1-p-Chlorophenyl-2,3-dimethyl-4-dimethylamino-2-butanol hydrochloride; Benzeneethanol, 4-chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methyl-, hydrochloride; p-Cloro-alpha-(2-(dimetilamino)-1-metiletil)-alpha-metil fenetil alcool cloridrato [Italian]

Indication

Disease Entry	ICD 11	Status	REF
Cough	MD12	Withdrawn from market	[1]

• ATC Code:
  R05DB03: Clobutinol
  R05DB: Other cough suppressants
  R05D: COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
  R05: COUGH AND COLD PREPARATIONS
  R: RESPIRATORY SYSTEM
  R05DB03: Clobutinol
  R05DB: Other cough suppressants
  R05D: COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
  R05: COUGH AND COLD PREPARATIONS
  R: RESPIRATORY SYSTEM
• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C14H22ClNO
  Canonical SMILES: CC(CN(C)C)C(C)(CC1=CC=C(C=C1)Cl)O
  InChI: InChI=1S/C14H22ClNO/c1-11(10-16(3)4)14(2,17)9-12-5-7-13(15)8-6-12/h5-8,11,17H,9-10H2,1-4H3
  InChIKey: KVHHQGIIZCJATJ-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 26937
  ChEBI ID: CHEMBL94381
  CAS Number: 14860-49-2
  UNII: 1NY2IX043A
  DrugBank ID: DB09004
  TTD ID: D06UWD
• Drug Pharmacogenomic Perturbation (DPP)NEW: Click to Jump to the Detailed DPP Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015