Details of the Drug

General Information of Drug (ID: DMJBIBK)

Drug Name

MB07133

Synonyms

MB-7133; MB-07133; 685111-92-6; CHEMBL218922; SCHEMBL12132117; HY-16311; CS-0006286; Z-3285; 2(1H)-PYRIMIDINONE, 4-AMINO-1-[5-O-[(2R,4S)-2-OXIDO-4-(4-PYRIDINYL)-1,3,2-DIOXAPHOSPHORINAN-2-YL]-BETA-D-ARABINOFURANOSYL]-

Indication

Disease Entry	ICD 11	Status	REF
Hepatocellular carcinoma	2C12.02	Phase 1/2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C17H21N4O8P
Canonical SMILES: C1COP(=O)(OC1C2=CC=NC=C2)OCC3C(C(C(O3)N4C=CC(=NC4=O)N)O)O
InChI: 1S/C17H21N4O8P/c18-13-3-7-21(17(24)20-13)16-15(23)14(22)12(28-16)9-27-30(25)26-8-4-11(29-30)10-1-5-19-6-2-10/h1-3,5-7,11-12,14-16,22-23H,4,8-9H2,(H2,18,20,24)/t11-,12+,14+,15-,16+,30?/m0/s1
InChIKey: HOAHIHGOMCBTFW-WUTQSZGESA-N

Cross-matching ID

PubChem CID: 44418783
UNII: BNL5ERR07R
DrugBank ID: DB17139
TTD ID: D0D1CL

References

1	ClinicalTrials.gov (NCT00073736) Safety and Tolerability of I.V. Infusion of MB07133 in Patients With Unresectable Hepatocellular Carcinoma. U.S. National Institutes of Health.