Details of the Drug

General Information of Drug (ID: DMJCXHM)

• Drug Name: ISIS 15770

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]

• Therapeutic Class: Anticancer Agents
• Drug Type: Antisense drug
• Sequence: ATGCATTCTGCCCCCAAGGA
• Cross-matching ID: TTD ID: D08KOD

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Raf messenger RNA (Raf mRNA)	TTAN5W2	RAF1_HUMAN	Not Available	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Solid tumour/cancer
• ICD Disease Classification: 2A00-2F9Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Raf messenger RNA (Raf mRNA)	DTT	RAF1	2.12E-04	0.49	2.78

References

• [1] US patent application no. 7,425,545, Modulation of C-reactive protein expression.