Details of the Drug

General Information of Drug (ID: DMJF6S0)

Drug Name
Sphinx
Synonyms
SPHINX; AC1NI3K3; SCHEMBL15648757; US9695160, SPHINX; BDBM221070; ZINC6790230; AKOS001099848; MCULE-7133870197; 5-methyl-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]furan-2-carboxamide; 5-methyl-N-(2-morpholino-5-(trifluoromethyl)phenyl)furan-2-carboxamide; 5-methyl-N-[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide; 848057-98-7
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 354.32
Logarithm of the Partition Coefficient (xlogp) 3.2
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C17H17F3N2O3
IUPAC Name
5-methyl-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Canonical SMILES
CC1=CC=C(O1)C(=O)NC2=C(C=CC(=C2)C(F)(F)F)N3CCOCC3
InChI
InChI=1S/C17H17F3N2O3/c1-11-2-5-15(25-11)16(23)21-13-10-12(17(18,19)20)3-4-14(13)22-6-8-24-9-7-22/h2-5,10H,6-9H2,1H3,(H,21,23)
InChIKey
FZCPNRVICXFZJR-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
4799939
ChEBI ID
CHEMBL5184609
TTD ID
D0LA9D
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SRSF protein kinase 1 (SRPK1) TTU3WV6 SRPK1_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Piperazine derivatives for treating disorders. US9695160.