Details of the Drug

General Information of Drug (ID: DMJN1SA)

Drug Name
GKT-136901
Synonyms GKT-02; Nox4 inhibitors (oral); NADPH oxidase 4 inhibitors (oral), GenKyoTex; Nox4 inhibitors (oral), GenKyoTex
Indication
Disease Entry ICD 11 Status REF
Cardiovascular disease BA00-BE2Z Investigative [1]
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C19H15ClN4O2
Canonical SMILES
CC1=C2C(=CC(=O)N1CC3=CC=CC=N3)NN(C2=O)C4=CC=CC=C4Cl
InChI
InChI=1S/C19H15ClN4O2/c1-12-18-15(10-17(25)23(12)11-13-6-4-5-9-21-13)22-24(19(18)26)16-8-3-2-7-14(16)20/h2-10,22H,11H2,1H3
InChIKey
DNKYHHFCPXKFIY-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
17027464
ChEBI ID
CHEMBL1276946
CAS Number
955272-06-7
TTD ID
D06UEP
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.