Details of the Drug

General Information of Drug (ID: DMJPW7C)

• Drug Name: C06909
• Synonyms: Cidofovir - Vistide; AC1LAD1W; SCHEMBL151807; CHEMBL27710; US10071110, Compound CDV; BDBM275767; AKOS015901501; RL00545; US10071110, Compound Cidofovir(CDV); SC-20872; AB0109968; C06909; A803101; I14-14184; Phosphonic acid, [[2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-; [1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid; [1-(4-amino-2-oxo-1-pyrimidinyl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid; [1-[(4-amino-2-oxo-pyrimidin-1-yl)methyl]-2-hydroxy-ethoxy]methylphosphon
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 1:
  Molecular Weight (mw); 279.19
  Logarithm of the Partition Coefficient (xlogp); -3.6
  Rotatable Bond Count (rotbonds); 6
  Hydrogen Bond Donor Count (hbonddonor); 4
  Hydrogen Bond Acceptor Count (hbondacc); 6
• Chemical Identifiers:
  Formula: C8H14N3O6P
  IUPAC Name: [1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid
  Canonical SMILES: C1=CN(C(=O)N=C1N)CC(CO)OCP(=O)(O)O
  InChI: InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)
  InChIKey: VWFCHDSQECPREK-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 466146
  ChEBI ID: CHEMBL27710
  TTD ID: D0XA0Y
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Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cytomegalovirus Protease (CMV UL80)	TT5DOVB	SCAF_HCMVA	Inhibitor	[1]

References

• [1] Phosphonate compounds. US10071110.