Details of the Drug

General Information of Drug (ID: DMJSADP)

Drug Name
BI 2536
Synonyms BI2536, BI 2536
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Phase 2 [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 521.7
Logarithm of the Partition Coefficient (xlogp) 3.7
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C28H39N7O3
IUPAC Name
4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
Canonical SMILES
CC[C@@H]1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
InChI
InChI=1S/C28H39N7O3/c1-5-22-27(37)34(3)23-17-29-28(32-25(23)35(22)20-8-6-7-9-20)31-21-11-10-18(16-24(21)38-4)26(36)30-19-12-14-33(2)15-13-19/h10-11,16-17,19-20,22H,5-9,12-15H2,1-4H3,(H,30,36)(H,29,31,32)/t22-/m1/s1
InChIKey
XQVVPGYIWAGRNI-JOCHJYFZSA-N
Cross-matching ID
PubChem CID
11364421
CAS Number
755038-02-9
UNII
4LJG22T9C6
DrugBank ID
DB16107
TTD ID
D0O0LQ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Polo-like kinase 1 (PLK1) TTIYVQP PLK1_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Acute myeloid leukaemia
ICD Disease Classification 2A60
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Polo-like kinase 1 (PLK1) DTT PLK1 4.16E-07 -0.38 -0.72
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 0.0001 5.3142 -2.657 16.4316
TC71 CTRP2 -8.7019 -7.1699 -8.7019 90.8776
A-673 GDSC2; CTRP2 -8.5148 -7.8524 -8.5148 90.3171
SK-N-MC CTRP2 -8.3275 -7.8337 -8.3275 89.0848
HOS GDSC2; CTRP2 -8.1666 0.5859 -8.4456 75.8866
EW-22 GDSC2 -7.1647 -4.927 -7.1665 71.2742
ES8 GDSC1; GDSC2 -6.2299 -4.5192 -6.2305 62.4517
MG-63 GDSC2; CTRP2 -5.7248 5.5543 -6.8515 63.2881
MHH-ES-1 GDSC2; CTRP2 -5.5134 -3.8254 -5.5134 65.9434
EW-1 GDSC1; GDSC2 -5.34 -4.0177 -5.3402 53.5818
SK-ES-1 GDSC1; GDSC2; CTRP2 -5.0648 -3.4228 -5.0648 67.3418
HuO9 GDSC2 -4.8727 0.9018 -5.5888 49.1859
ES6 GDSC1; GDSC2 -4.8369 -1.3936 -4.9738 48.6522
EW-16 GDSC1; GDSC2 -4.8082 -3.3192 -4.8093 48.249
ES4 GDSC1; GDSC2 -4.275 -2.5311 -4.2822 42.9266
SK-PN-DW GDSC1; GDSC2 -3.9774 -1.1235 -4.0936 40.3774
SaOS-2 GDSC2; CTRP2 -3.7194 4.0031 -4.2569 56.5862
ES1 GDSC1; GDSC2 -3.619 -2.8612 -3.619 36.3143
EW-3 GDSC1; GDSC2 -3.3752 -1.1986 -3.4387 34.1787
TC-71 GDSC1; GDSC2 -3.055 -1.3845 -3.0819 30.79
SJSA-1 GDSC1; GDSC2; CTRP2 -2.8493 2.5893 -3.0453 52.35
ES7 GDSC1; GDSC2 -1.917 0.4742 -2.2384 20.9602
EW-12 GDSC1; GDSC2 -1.4279 0.1744 -1.9732 7.5301
SW1353 CTRP2 -1.3281 3.1446 -1.4986 42.8409
NY GDSC2 -1.3115 8.1688 -5.223 31.6238
EW-18 GDSC1; GDSC2 -1.2518 2.7034 -2.4975 19.7291
ES5 GDSC1; GDSC2 -1.2214 0.8076 -2.0944 7.6004
U2OS GDSC2; CTRP2; CTRP1 -1.156 5.1739 -1.7554 40.1651
H-EMC-SS GDSC1; GDSC2 -0.8842 2.7909 -2.1868 16.5756
CADO-ES1 GDSC2 -0.8307 1.3813 -1.4643 12.0059
EW-24 GDSC1; GDSC2 -0.7152 3.6138 -2.4328 17.4355
G-292 clone A141B1 GDSC2; CTRP2 -0.5794 5.3265 -1.1723 39.0132
EW-7 GDSC2 -0.5379 11.2443 -6.0765 31.5078
CHSA0011 GDSC2 -0.4677 4.7729 -3.4558 13.7769
CAL-72 GDSC2 0.0903 12.0226 -5.9362 29.3766
U-CH2 GDSC2 0.4895 6.6398 -3.661 12.5142
EW-11 GDSC1; GDSC2 0.8209 4.0796 -1.4028 6.7493
CAL-78 GDSC2; CTRP2 0.8948 9.2403 -1.0547 33.5535
HuO-3N1 GDSC2 1.2299 7.4126 -2.738 13.5471
EW-13 GDSC1; GDSC2 1.3046 5.7976 -1.8967 8.6211
CHSA0108 GDSC2 1.4527 4.6638 -2.1434 2.5074
NOS-1 [Human HNSCC] GDSC1; GDSC2 1.5392 7.8907 -2.7478 12.8621
Hs 888.T CTRP2 1.8781 13.8502 -2.2125 33.309
CHSA8926 GDSC2 1.9385 3.7757 -0.6197 0.7877
Hs 822.T CTRP2 2.8042 5.8259 2.3491 16.5646
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 219 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -8.2162 -7.6529 -8.2162 88.3422
JK1 CTRP2 -6.1354 -0.5011 -6.2001 71.238
JM1 GDSC1; GDSC2; CTRP2 -5.8864 -4.5023 -5.8864 68.2762
PL21 CTRP2; CTRP1 -11.364 -9.3996 -11.364 98.8691
MOLT-3 CTRP2 -11.2027 -10.0358 -11.2027 99.6712
KMS-11 GDSC2; CTRP2; CTRP1 -10.8584 3.9261 -12.0163 74.3281
HuT 78 CTRP2 -9.7934 -3.0629 -9.8413 85.4325
SR GDSC1; GDSC2; CTRP2 -9.7468 -3.9994 -9.765 87.237
EB1 CTRP2 -9.7063 -0.7823 -9.9158 81.0735
Mono-Mac-1 CTRP2 -9.5906 3.4295 -10.5169 74.5727
KMS-18 CTRP2 -9.2105 16.2056 -14.5252 63.7464
NB4 GDSC1; GDSC2; CTRP2 -8.9823 -6.259 -8.9823 86.1912
MOLM-6 CTRP2 -8.982 3.8713 -9.9593 72.9632
L-363 GDSC1; GDSC2; CTRP2 -8.8803 0.9578 -9.2629 76.7908
MOLT-13 GDSC1; GDSC2; CTRP2 -8.8794 -4.1076 -8.8865 85.9281
HPB-ALL CTRP2 -8.8777 -7.9561 -8.8777 92.5496
KO52 CTRP2 -8.8179 0.3457 -9.108 77.6381
KMS-34 CTRP2 -8.6934 -7.8739 -8.6934 91.4424
U-937 CTRP2; CTRP1 -8.6902 -7.6554 -8.6902 91.3077
MJ CTRP2 -8.6482 34.9949 -22.4537 57.6369
BL-70 CTRP2; CTRP1 -8.6282 -7.1964 -8.6282 90.5735
JeKo-1 GDSC2; CTRP2 -8.5884 -8.0014 -8.5884 85.1545
MOTN-1 CTRP2 -8.5741 3.3122 -9.3833 72.8818
OCI-Ly3 CTRP2 -8.4114 -7.6868 -8.4114 89.6248
OPM-2 GDSC1; GDSC2; CTRP2 -8.3984 -2.6142 -8.4301 81.9624
SEM CTRP2 -8.3646 -7.8552 -8.3646 89.3308
Pfeiffer CTRP2 -8.3597 -7.5942 -8.3597 89.2772
BCP-1 CTRP2 -8.3331 -6.9161 -8.3331 88.7939
M-07e CTRP2 -8.3297 -6.4719 -8.3297 88.3402
Kasumi-2 CTRP2 -8.2495 -1.0316 -8.3624 78.7541
Mino CTRP2 -8.2283 -7.7595 -8.2283 88.4239
HEL 92.1.7 CTRP2 -8.0514 -1.209 -8.1429 81.4202
HuNS1 CTRP2 -7.6767 -5.8223 -7.6767 84.3882
Ci-1 CTRP2 -7.624 -6.1218 -7.624 84.2526
Peer CTRP2 -7.6043 -6.6514 -7.6043 84.2549
CMK CTRP2 -7.4886 -6.5007 -7.4886 83.4849
RPMI-8402 GDSC1; GDSC2; CTRP2 -7.4517 -6.8544 -7.4517 83.2505
P12-Ichikawa CTRP2 -7.3357 -6.843 -7.3357 82.4778
CML-T1 GDSC2; CTRP2 -7.2633 -6.4635 -7.2633 81.9945
NCO2 CTRP2 -7.2067 -5.8937 -7.2067 81.5794
KMS-21-BM CTRP2 -7.1887 -5.9574 -7.1887 81.4723
DB GDSC1; GDSC2; CTRP2 -7.184 0.2382 -7.3603 73.8734
SUP-T1 GDSC1; GDSC2; CTRP2 -7.0186 1.5507 -7.3574 71.5135
KMS-26 CTRP2 -7.0029 -6.3448 -7.0029 80.2609
KYO-1 CTRP2 -6.9335 -0.514 -7.0288 74.2165
BE-13 GDSC1; GDSC2 -6.9143 -1.4226 -7.2104 64.4275
EoL-1 GDSC1; GDSC2; CTRP2 -6.9082 -2.5371 -6.918 77.0811
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 -6.872 6.4887 -8.3816 63.7845
KE-37 GDSC1; GDSC2; CTRP2 -6.6992 -5.766 -6.6992 78.236
A4/Fukuda GDSC1; GDSC2; CTRP2 -6.6861 -1.7108 -6.7114 75.0514
MY-M12 GDSC1; GDSC2 -6.6814 -4.5948 -6.6862 56.9337
BV-173 GDSC1; GDSC2; CTRP2 -6.6625 0.1092 -6.7976 72.4023
ALL-SIL GDSC1; GDSC2; CTRP2 -6.6597 -4.9425 -6.6597 77.8989
SUP-B8 GDSC2 -6.6372 -5.193 -6.6374 56.562
ALL-PO GDSC1; GDSC2 -6.4844 -4.2191 -6.4882 64.7379
SET-2 CTRP2 -6.4512 -3.38 -6.452 75.8634
Hs 611.T CTRP2 -6.4399 7.8157 -8.3419 63.5162
ME1 CTRP2 -6.3709 53.4766 -29.2379 53.5604
SU-DHL-5 GDSC2; CTRP1 -6.3415 -3.814 -6.3416 75.5606
ML-2 GDSC1; GDSC2 -6.3408 -2.1711 -6.4706 61.6591
PF-382 GDSC1; GDSC2; CTRP2 -6.2811 -4.2484 -6.2811 75.3385
Ri-1 CTRP2 -6.1993 6.0412 -7.5123 64.2773
697 GDSC1; GDSC2; CTRP2 -6.199 -5.1215 -6.199 74.9035
Namalwa GDSC1; GDSC2; CTRP2 -6.194 -4.1751 -6.194 74.7715
SKM-1 GDSC1; GDSC2; CTRP2; CTRP1 -6.1854 -4.4432 -6.1854 70.1601
GA-10 GDSC1; GDSC2; CTRP2 -6.1733 -5.0308 -6.1733 74.7315
CRO-AP2 GDSC2 -6.0747 -2.711 -6.1821 50.856
Karpas-45 GDSC1; GDSC2 -6.024 -2.0391 -6.1504 59.1308
Jurkat GDSC2; CTRP2 -6.0239 -5.1996 -6.0239 73.7387
NALM-6 GDSC1; GDSC2; CTRP2 -5.9815 -4.4846 -5.9815 73.4432
KMS-12-BM GDSC1; GDSC2; CTRP2 -5.9787 -5.1824 -5.9787 73.4371
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 -5.9785 -4.5974 -5.9785 68.8795
PL-21 GDSC1; GDSC2 -5.9218 -3.1807 -5.9692 49.4133
RS4;11 GDSC1; GDSC2; CTRP2 -5.9215 -4.2732 -5.9215 73.0339
RL GDSC1; GDSC2; CTRP2 -5.8795 -3.0404 -5.88 68.0797
MOLM-13 GDSC1; GDSC2; CTRP2 -5.8731 -4.6036 -5.8731 72.7309
OCI-AML-2 GDSC1; GDSC2; CTRP2 -5.8645 -4.3315 -5.8645 72.6636
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 -5.861 -3.8544 -5.861 72.612
Reh GDSC1; GDSC2; CTRP2 -5.8513 -2.818 -5.8524 72.1369
Karpas-231 GDSC1; GDSC2 -5.8425 -4.9096 -5.8425 58.6251
MOLM-16 GDSC2; CTRP2; CTRP1 -5.8318 -2.5533 -5.8339 67.6779
ST486 GDSC1; CTRP2 -5.8294 -2.4734 -5.8319 71.7946
Karpas-299 GDSC1; GDSC2; CTRP2 -5.8195 -2.3082 -5.8231 71.6221
Ki-JK CTRP2 -5.8014 -2.3159 -5.8048 71.5286
EM-2 GDSC1; GDSC2; CTRP2 -5.7742 -4.1707 -5.7742 72.0594
DEL GDSC1; GDSC2; CTRP2 -5.752 -4.6571 -5.752 71.9265
JJN-3 GDSC1; GDSC2; CTRP2 -5.7352 -3.9932 -5.7352 71.7898
HC-1 GDSC1; GDSC2 -5.6565 -5.0186 -5.6565 56.7589
TK [Human B-cell lymphoma] GDSC2 -5.6447 -4.6511 -5.6447 56.6453
CCRF-CEM GDSC1; GDSC2 -5.6294 -4.6023 -5.6295 56.4873
OCI-Ly19 GDSC1; GDSC2; CTRP2 -5.5833 -4.2957 -5.5833 66.3837
CTV-1 GDSC1; GDSC2 -5.5476 -4.8692 -5.5476 55.6667
Loucy GDSC1; GDSC2 -5.5131 -4.3642 -5.5131 55.3191
HL-60 GDSC1; GDSC2; CTRP2 -5.5082 -3.8121 -5.5082 70.2871
KM-H2 GDSC1; GDSC2; CTRP2 -5.5057 -2.6631 -5.5065 70.0188
JURL-MK1 GDSC2; CTRP2 -5.5028 -4.141 -5.5028 70.2638
HD-MY-Z CTRP2 -5.5016 5.4894 -6.5893 62.6365
JSC-1 GDSC1; GDSC2 -5.4631 -4.6734 -5.4631 54.8185
SU-DHL-1 GDSC1; GDSC2; CTRP2 -5.4573 -3.6885 -5.4573 65.5917
SU-DHL-6 GDSC1; GDSC2; CTRP2 -5.4409 -2.3655 -5.4424 69.4988
MOLT-4 GDSC1; GDSC2 -5.4386 -4.6983 -5.4386 54.5724
KE-97 CTRP2 -5.4191 -4.6887 -5.4191 69.7091
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 -5.4099 -3.8339 -5.4099 69.6688
HT GDSC1; GDSC2; CTRP2 -5.4055 -3.5946 -5.4055 65.2676
Ramos.2G6.4C10 GDSC1; GDSC2 -5.36 -3.1271 -5.3704 53.7273
SU-DHL-10 GDSC2; CTRP2 -5.3354 -3.689 -5.3354 69.1417
Raji GDSC1; GDSC2; CTRP2 -5.2976 -3.714 -5.2976 68.8922
RCH-ACV GDSC2; CTRP2 -5.2955 -4.3647 -5.2955 64.5862
SU-DHL-8 GDSC1; GDSC2; CTRP2 -5.2621 -2.823 -5.2623 68.558
SUP-M2 GDSC1; GDSC2; CTRP2 -5.2515 -3.4943 -5.2515 68.578
P32/ISH GDSC1; GDSC2 -5.2444 -4.4432 -5.2444 52.6243
MOLP-8 GDSC1; GDSC2; CTRP2 -5.2012 0.6753 -5.3148 65.8673
OCI-Ly7 GDSC2 -5.178 -4.2116 -5.178 41.9266
OCI-AML-5 GDSC1; GDSC2; CTRP2 -5.0941 -3.576 -5.0941 67.5398
BONNA-12 GDSC2 -5.0542 -2.5446 -5.118 40.9439
AML-193 CTRP2 -5.0508 4.6022 -5.8553 61.7841
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 -5.018 -3.653 -5.018 67.0675
NU-DHL-1 CTRP2 -5.0143 1.489 -5.2058 64.2688
A3/Kawakami GDSC1; GDSC2; CTRP2 -5.0102 -3.3527 -5.0102 66.9781
MV4-11 GDSC1; GDSC2; CTRP2 -4.9953 -3.594 -4.9953 66.8841
MOLT-16 GDSC1; GDSC2; CTRP2 -4.9951 -4.0581 -4.9951 66.8843
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 -4.9714 -3.6721 -4.9714 62.5958
BALL-1 GDSC1; GDSC2 -4.9704 -3.4377 -4.9715 49.8749
MOLP-2 CTRP2 -4.9483 11.7664 -8.2216 57.5178
ATN-1 GDSC1; GDSC2 -4.9071 -3.7371 -4.9072 49.2393
KCL-22 GDSC1; GDSC2; CTRP2 -4.8844 -2.7734 -4.8845 66.1152
K-562 GDSC1; GDSC2; CTRP2 -4.8685 -0.7344 -4.8878 65.2974
KMS-28BM CTRP2 -4.8589 6.349 -6.1458 59.8988
JVM-3 GDSC1; GDSC2; CTRP2 -4.8472 -2.8397 -4.8472 65.8767
MC116 GDSC1; GDSC2; CTRP2 -4.8457 -3.2203 -4.8457 61.7755
P3HR-1 CTRP2 -4.8204 -1.3362 -4.8267 65.3379
KOPN-8 GDSC1; GDSC2 -4.7742 -3.6507 -4.7743 47.9063
LAMA-84 GDSC1; GDSC2; CTRP2 -4.7667 -2.8351 -4.7668 65.3474
SIG-M5 GDSC1; GDSC2; CTRP2 -4.7481 -4.132 -4.7481 61.1671
Ku812 GDSC1; GDSC2; CTRP2 -4.7443 -1.2114 -4.7516 64.8293
F-36P CTRP2 -4.6745 4.2571 -5.358 60.604
Kasumi-1 GDSC1; GDSC2; CTRP2 -4.6599 -1.652 -4.6621 60.538
SUP-T11 CTRP2 -4.6307 24.1987 -13.4384 54.017
H9 GDSC1; GDSC2 -4.6307 -3.4895 -4.6308 46.4661
NKM-1 GDSC1; GDSC2 -4.6175 -2.6269 -4.6285 46.364
KY821 GDSC1; GDSC2 -4.5933 -2.695 -4.6017 46.1159
U266B1 GDSC1; GDSC2; CTRP2 -4.5723 1.4469 -4.7314 62.2202
VAL GDSC2 -4.5495 0.5919 -5.1385 46.5823
OCI-M1 GDSC1; GDSC2; CTRP2 -4.5094 -1.5031 -4.5119 63.4896
CA46 GDSC1; GDSC2; CTRP2 -4.4827 3.8767 -5.0588 60.0789
Farage GDSC1; GDSC2 -4.4379 -3.3292 -4.439 34.5055
ARH-77 GDSC1; GDSC2 -4.3841 -1.9859 -4.4227 44.1213
EJM GDSC1; GDSC2; CTRP2; CTRP1 -4.329 5.3028 -5.2541 58.6032
RPMI-6666 GDSC1; GDSC2; CTRP2 -4.3138 -1.0465 -4.3193 62.1448
MHH-PREB-1 GDSC1; GDSC2 -4.3095 -2.3863 -4.3221 43.2929
DoHH2 GDSC1; GDSC2 -4.2467 -3.2804 -4.2472 32.5833
MM1.S GDSC2; CTRP2 -4.2452 3.2281 -4.6617 59.4528
OCI-Ly10 CTRP2; CTRP1 -4.1512 4.4378 -4.8298 58.3559
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 -4.1318 0.1599 -4.1668 60.6478
NOMO-1 GDSC1; GDSC2; CTRP2; CTRP1 -4.0924 -1.5793 -4.0932 60.8662
WIL2 NS GDSC1; GDSC2 -4.0287 -2.5563 -4.0319 40.4405
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 -3.9689 -0.5021 -3.9792 56.2557
Hs 445 GDSC1; GDSC2 -3.894 -1.4392 -3.9604 39.363
Granta-519 GDSC1; GDSC2; CTRP2 -3.8734 4.0428 -4.4337 57.2899
Daudi GDSC1; GDSC2; CTRP2 -3.8358 -0.9568 -3.8388 59.0907
SU-DHL-16 GDSC1; GDSC2 -3.8253 -2.7151 -3.829 28.3708
L-540 GDSC1; GDSC2; CTRP2 -3.8161 0.7048 -3.8708 58.5401
HEL GDSC1; GDSC2; CTRP2 -3.8145 -1.6353 -3.8147 55.3315
CESS GDSC1; GDSC2 -3.7797 -0.0011 -4.1247 39.2778
SUP-HD1 GDSC1; GDSC2; CTRP2 -3.7698 0.304 -3.8015 58.398
JVM-2 GDSC1; GDSC2; CTRP2 -3.7664 1.7315 -3.9101 57.8408
QIMR-WIL GDSC1; GDSC2 -3.7111 -2.4251 -3.7224 27.2627
SCC-3 GDSC1; GDSC2 -3.6538 -2.7821 -3.6539 36.6642
Karpas-1106P GDSC2 -3.6475 3.632 -5.3368 41.5433
Mono-Mac-6 GDSC1; GDSC2; CTRP2 -3.6345 2.0914 -3.8146 56.9649
RPMI-8866 GDSC1; GDSC2 -3.5862 -2.4454 -3.5872 35.9903
BC-3 GDSC1; GDSC2 -3.5305 -0.673 -3.8574 27.0937
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 -3.5175 2.7169 -3.7811 53.1252
VL51 GDSC1; GDSC2 -3.5007 0.575 -3.9916 37.1906
TF-1 CTRP2 -3.4887 4.3772 -4.0947 55.3354
DG-75 GDSC1; GDSC2 -3.4668 -0.4919 -3.6614 35.6869
DND-41 GDSC1; GDSC2; CTRP2 -3.304 8.4173 -5.1678 53.4033
L-428 GDSC1; GDSC2; CTRP2 -3.2633 1.323 -3.3398 55.0546
CTB-1 GDSC1; GDSC2 -3.2626 1.1972 -4.2864 28.0305
GR-ST GDSC1; GDSC2 -3.2304 1.7997 -4.1399 36.2472
KHM-1B CTRP2 -2.9839 2.6705 -3.2017 53.1253
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 -2.9483 4.3665 -3.5007 52.6676
KMOE-2 GDSC1; GDSC2 -2.8971 0.1808 -3.2129 30.6537
P30/OHK GDSC1; GDSC2 -2.7462 3.728 -4.4576 34.9254
Jiyoye GDSC1; GDSC2 -2.6128 -0.9633 -2.6577 26.446
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 -2.3939 2.5315 -2.5507 49.5852
Karpas-422 GDSC1; GDSC2; CTRP2 -2.3779 1.4606 -2.4271 49.4631
LC4-1 GDSC1; GDSC2 -2.3372 2.1817 -3.3571 28.6979
MLMA GDSC1; GDSC2 -2.1814 1.305 -2.8309 25.3616
NK-92MI GDSC1; GDSC2 -2.1741 -0.5682 -2.4206 13.123
HDLM-2 GDSC1; GDSC2; CTRP2 -2.1595 6.5774 -3.2838 48.5216
BC-1 GDSC1; GDSC2 -1.8232 0.0777 -2.0115 19.2901
MHH-CALL-4 GDSC2; CTRP2 -1.7542 7.9513 -3.3314 44.5976
MEG-01 GDSC1; GDSC2 -1.6802 0.8947 -2.1371 19.3639
NCI-H929 GDSC2; CTRP2 -1.6241 2.8847 -1.7774 44.7139
SUP-B15 GDSC1; GDSC2; CTRP2 -1.6018 5.391 -2.3063 45.2759
L-1236 GDSC1; GDSC2 -1.4167 2.859 -2.7319 21.6687
P31/FUJ GDSC1; GDSC2; CTRP2 -1.2263 3.2862 -1.4116 42.2146
HAL-01 GDSC1; GDSC2 -1.1844 0.1873 -1.3482 12.7606
EB2 GDSC1; GDSC2 -1.111 1.9325 -1.9977 16.2739
KMS-20 CTRP2 -1.0611 6.7349 -2.1465 42.7192
U-698-M GDSC1; GDSC2 -0.9874 0.3855 -1.2029 11.0819
EHEB GDSC1; CTRP2 -0.8586 4.1402 -1.1752 40.1437
TUR GDSC1; GDSC2 -0.8113 0.0385 -0.8962 8.5903
MHH-CALL-3 CTRP2 -0.7662 83.2468 -38.9987 48.8958
IM-9 GDSC1; GDSC2 -0.648 0.201 -0.7707 7.1663
KG-1 GDSC1; GDSC2 -0.5003 0.7919 -0.8635 7.1194
ME1 GDSC1; GDSC2 -0.3747 7.2243 -3.9289 23.8824
KMS-27 CTRP2 -0.1972 4.9792 -0.6582 36.2846
SK-MM-2 GDSC1; GDSC2; CTRP2 -0.188 3.1327 -0.28 35.1544
ROS-50 GDSC1; GDSC2 -0.1564 5.7479 -3.6993 14.311
YT GDSC1; GDSC2 -0.0311 1.9794 -1.0157 6.5215
WSU-NHL GDSC1 0.5383 2.3669 -2.5629 0.501
MN-60 GDSC1; GDSC2 0.6078 5.0554 -2.0407 11.1479
Toledo CTRP2 5.5345 27.3551 -5.7052 31.6372
Karpas-620 GDSC1; GDSC2; CTRP2 5.6866 7.3355 4.3796 1.7706
KMM-1 CTRP2 6.3182 11.0136 3.0432 6.2414
BL-41 GDSC1; GDSC2; CTRP2 7.1866 28.0047 -4.703 27.4554
REC-1 CTRP2 7.4992 9.3111 4.4521 0.2731
⏷ Show the Full List of 219 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 -7.2397 19.2847 -13.807 59.4777
TE8 CTRP2 -4.5699 13.3025 -8.4605 56.0312
TE-8 GDSC1; GDSC2 -6.605 -4.9932 -6.6051 66.2023
TE-15 GDSC1; GDSC2 -5.7297 -4.0361 -5.7306 57.4665
TE-10 GDSC1; GDSC2; CTRP2 -5.6826 -3.4199 -5.6826 66.9662
TE-11 GDSC1; GDSC2; CTRP2 -5.3253 -3.7579 -5.3253 64.771
TE-9 GDSC1; GDSC2; CTRP2 -5.0749 -2.916 -5.075 67.3717
TE-6 GDSC1; GDSC2; CTRP2 -5.0392 -0.7913 -5.0601 66.2783
TE-4 GDSC2; CTRP2 -4.1448 2.2973 -4.3896 59.5385
KYSE-180 GDSC2; CTRP2 -3.9372 -0.4121 -3.9491 59.6297
TE-14 CTRP2 -3.8228 4.1263 -4.3983 57.0162
OE21 GDSC2; CTRP2 -2.946 4.7098 -3.5867 52.5596
KYSE-510 GDSC2; CTRP2 -2.2616 3.3208 -2.5331 45.9981
TE-5 GDSC1; GDSC2; CTRP2 -1.8023 8.1592 -3.4609 47.0232
KYSE-410 GDSC2; CTRP2 -1.6208 5.4566 -2.3462 45.4052
KYSE-150 GDSC2; CTRP2 -1.1225 6.4308 -2.1096 42.9232
T.T GDSC2 0.3368 7.4366 -3.4415 19.5194
KYSE-140 GDSC2; CTRP2 0.408 7.0053 -0.6596 34.1369
EC-GI-10 GDSC1; GDSC2; CTRP2 0.4645 8.1866 -1.0606 34.9651
KYSE-450 GDSC2; CTRP2 0.4893 9.1132 -1.4201 35.7118
KYSE-70 GDSC2; CTRP2 0.9386 9.0612 -0.9321 33.108
KYSE-520 GDSC2; CTRP2 1.466 12.9753 -2.191 34.3772
KYSE-270 GDSC2 1.504 8.9797 -3.3064 15.7935
KYSE-30 CTRP2 2.0267 13.2034 -1.7596 31.947
COLO 680N GDSC2; CTRP2 2.2666 7.8999 0.9413 23.3411
TE-1 GDSC1; GDSC2; CTRP2 2.5445 11.2693 -0.3362 26.8444
OE19 GDSC2; CTRP2 3.2659 18.6414 -3.2877 32.06
OE33 GDSC2; CTRP2 3.4067 12.7648 -0.2532 24.4414
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.285 25.4621 -6.6653 36.7027
PaTu 8988s CTRP2 -6.7554 7.9024 -8.7131 64.2239
MIA PaCa-2 GDSC2; CTRP2 -6.0774 -0.3505 -6.1495 70.8136
KP-4 GDSC2; CTRP2 -5.5454 -1.8681 -5.5514 69.803
L3.3 CTRP2 -5.3252 -2.6812 -5.3256 68.9174
MZ-PC-1 GDSC1; GDSC2 -3.5981 1.1546 -4.617 31.0729
PL4 GDSC2 -3.4275 1.6552 -4.2941 37.8125
QGP-1 GDSC2; CTRP2 -2.5917 8.2427 -4.3384 48.4565
Panc 10.05 GDSC2; CTRP2 -2.0198 4.0788 -2.4244 47.4325
PSN1 GDSC1; GDSC2; CTRP2 -2.0147 7.1741 -3.3306 47.8764
Panc 08.13 GDSC2; CTRP2 -0.9723 2.9464 -1.0905 40.408
AsPC-1 GDSC2; CTRP2 -0.9589 5.9888 -1.7875 41.7489
DAN-G GDSC2; CTRP2 -0.7691 7.2055 -1.9983 41.3237
KP-1N GDSC2 -0.7128 5.8205 -3.5237 23.1732
KP-3 GDSC2; CTRP2 -0.6653 4.6241 -1.0772 39.1361
BxPC-3 GDSC2; CTRP2 -0.6227 6.3496 -1.5402 39.9468
PaTu 8988t GDSC2; CTRP2 -0.6152 4.9823 -1.1152 39.0253
PaTu 8902 GDSC2; CTRP2; CTRP1 0.025 5.2878 -0.499 35.0989
Panc 02.03 GDSC2; CTRP2 0.025 8.4829 -1.6443 37.7533
HuP-T4 GDSC2; CTRP2 0.0334 2.6892 -0.0042 33.5082
SU.86.86 GDSC2; CTRP2 0.6614 7.0442 -0.4026 32.5746
Hs 766T GDSC2; CTRP2 0.741 5.5772 0.1923 30.4983
SW1990 GDSC2; CTRP2 0.9158 5.7366 0.3323 29.4757
TCC-Pan2 CTRP2 1.294 7.6279 0.0409 29.2274
SUIT-2 GDSC2; CTRP2 1.5564 7.3654 0.4241 27.1862
PK-45H CTRP2 1.5569 4.8902 1.2793 24.196
SNU-213 CTRP2 1.753 4.015 1.6721 22.2027
Capan-1 GDSC2; CTRP2 1.8607 6.2531 1.1784 23.64
Panc 05.04 CTRP2 2.1948 4.4582 2.0727 19.4033
HuP-T3 GDSC2; CTRP2 2.2013 6.8749 1.303 22.2006
Panc 03.27 GDSC2; CTRP2 2.2771 12.1858 -1.0316 29.5093
PK-59 CTRP2 2.3495 8.3936 0.8088 23.5882
HPAC GDSC2; CTRP2 2.3713 4.2993 2.2916 18.08
Capan-2 CTRP2 2.5464 5.2066 2.2723 17.6063
CFPAC-1 GDSC2; CTRP2 2.8239 4.1056 2.7986 14.8785
YAPC GDSC2; CTRP2 2.8943 6.3776 2.2355 16.742
HPAF-II CTRP2 2.8993 15.3768 -2.0027 30.304
KP-2 GDSC2; CTRP2 3.1076 8.8739 1.3467 19.6152
Panc 04.03 GDSC2; CTRP2 3.725 9.3525 1.7117 16.7007
SNU-410 CTRP2 6.3934 8.8483 4.1143 1.9468
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 0.4349 10.0624 -1.8862 36.8533
Hs 294T CTRP2 -14.4881 7.6614 -17.0401 75.8753
HMCB CTRP2 -11.0422 11.5679 -14.6425 69.0096
CJM [Human melanoma] CTRP2 -9.4044 19.2568 -16.0206 62.6776
WM983B CTRP2 -8.2941 5.0565 -9.5156 70.2642
Mel JuSo GDSC2; CTRP2 -6.7408 16.2524 -11.9719 59.6893
CHL-1 GDSC2 -5.7434 -2.6191 -5.7926 57.1699
RPMI-7951 GDSC2; CTRP2 -5.7165 -2.6212 -5.7178 71.2463
MDA-MB-435S CTRP2 -5.5305 -0.5042 -5.575 68.5518
A-388 GDSC1; GDSC2 -4.9127 -0.8788 -5.3038 40.6612
CP50-MEL-B GDSC2 -4.909 1.0399 -5.9559 42.2274
LOX-IMVI GDSC1; GDSC2; CTRP2 -4.1238 0.5075 -4.1775 60.4078
Hs 944.T CTRP2 -3.9934 6.8013 -5.349 56.5379
A101D GDSC1; GDSC2; CTRP2 -3.9563 -0.7644 -3.9622 59.8302
DJM-1 GDSC1; GDSC2 -3.9336 -0.3772 -4.3909 31.6857
A2058 GDSC2; CTRP2 -3.4348 3.7075 -3.8814 55.3031
LB2518-MEL GDSC1; GDSC2 -3.3517 -1.391 -3.4713 24.2177
MZ-MEL-2 GDSC1; GDSC2 -3.3279 -0.4299 -3.7163 25.4123
Hs 852.T CTRP2; CTRP1 -3.304 11.717 -6.4679 52.8283
IGR-1 GDSC2; CTRP2 -3.0654 4.5612 -3.679 53.1943
WM793 GDSC2; CTRP2 -2.5489 2.8846 -2.7684 50.534
IGR-37 GDSC2; CTRP2 -2.329 3.81 -2.7021 49.2347
WM35 GDSC2 -2.2241 1.161 -2.8199 25.4945
Hs 936.T CTRP2 -2.0889 9.0602 -4.1136 48.4429
WM278 GDSC2 -1.9764 1.6505 -2.7563 24.0739
IST-MEL1 GDSC1; GDSC2 -1.741 4.3131 -3.7366 27.8937
WM88 CTRP2 -1.5499 21.7897 -9.3039 47.9424
CP66-MEL GDSC1; GDSC2 -1.5232 2.0235 -2.9672 14.0178
COLO 800 GDSC1; GDSC2; CTRP2 -1.4139 5.2288 -2.0549 41.6634
A-375 GDSC2; CTRP2; CTRP1 -1.1827 6.0971 -2.0621 40.8251
A-431 GDSC2 -1.028 6.8911 -4.9689 22.9847
LB373-MEL-D GDSC1; GDSC2 -0.8129 4.3337 -3.5126 15.0668
MZ-MEL-7 GDSC1; GDSC2 -0.7223 4.2524 -3.3985 14.1527
SH-4 GDSC1; GDSC2 -0.5813 6.6947 -3.8433 24.1783
CP67-MEL GDSC1 -0.567 5.0022 -4.3641 13.6423
K029AX CTRP2 -0.5189 88.9457 -41.628 48.8113
WM115 GDSC2; CTRP2 -0.2348 5.3657 -0.8078 36.8173
SK-MEL-5 GDSC2; CTRP2; CTRP1 0.1202 5.7816 -0.5442 32.8109
COLO 792 GDSC2; CTRP2 0.1572 5.025 -0.2838 33.9491
Hs 940.T GDSC2; CTRP2 0.194 3.8135 0.0292 30.8129
WT2-iPS GDSC2 0.3774 5.8634 -2.6234 13.8861
MeWo GDSC2; CTRP2 0.4245 4.6205 0.1116 31.8083
G-mel GDSC2 0.4376 5.5021 -3.1449 9.7629
Hs 938.T GDSC2 0.6374 5.4595 -2.9882 8.4366
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 0.6477 5.2058 0.2039 30.8328
Mel Ho GDSC2; CTRP2 0.8514 6.1729 0.1171 28.5427
SK-MEL-2 GDSC1; GDSC2 0.8617 6.1933 -2.4111 12.6564
Malme-3M CTRP2 0.9873 4.8305 0.6733 28.0996
IPC-298 GDSC2; CTRP2 1.0235 7.9422 -0.3722 29.5218
G-361 GDSC2; CTRP2 1.0272 4.7612 0.7343 27.7631
MMAc-SF GDSC1; GDSC2 1.0469 6.5445 -3.2332 8.9724
COLO 679 GDSC2 1.12 6.7884 -2.5121 12.5803
COLO 741 CTRP2 1.1542 13.1351 -2.5703 35.9586
WM1552C GDSC2 1.2036 11.072 -4.5677 22.0035
VMRC-MELG GDSC2 1.208 11.2541 -5.3986 18.9544
COLO 783 GDSC2 1.2509 2.7523 -1.4862 0.2498
451Lu GDSC2 1.3394 3.1238 -1.5854 0.4449
SK-MEL-24 GDSC2; CTRP2 1.3867 3.6957 1.3239 24.5802
IGR-39 CTRP2 1.4043 10.6754 -1.1779 32.3105
RVH-421 GDSC2; CTRP2 1.4341 3.9455 1.3409 22.8481
HMV-II GDSC2 1.5817 7.4831 -2.5194 11.5342
SK-MEL-31 GDSC2; CTRP2 1.7316 9.4238 -0.2799 27.291
GAK GDSC1; GDSC2 1.7866 6.4114 -1.8671 7.4446
HT-144 GDSC1; GDSC2; CTRP2 1.8042 10.9542 -0.9092 30.4756
WM1799 CTRP2 2.2027 7.5799 1.0127 23.2603
Hs 934.T CTRP2 2.379 2.979 2.3789 17.7575
SK-MEL-30 GDSC2; CTRP2 2.5322 4.3011 2.4641 15.9093
SK-MEL-3 GDSC2; CTRP2 2.5507 11.2238 -0.3084 25.2983
Hs 895.T CTRP2 2.6591 6.5267 1.9269 18.5733
UACC-257 GDSC1; GDSC2; CTRP2 2.7641 13.0652 -0.9952 28.1582
Hs 688(A).T CTRP2 3.0795 5.1288 2.8764 13.8037
SK-MEL-28 GDSC2; CTRP2; CTRP1 3.6905 4.0567 3.6905 8.5396
UACC-62 GDSC2; CTRP2 3.7268 12.1599 0.3367 21.7756
WM266-4 CTRP2 4.8729 22.7935 -3.9735 30.0733
COLO 829 GDSC1; GDSC2; CTRP2 5.0755 17.6604 -1.2377 23.6799
Hs 839.T CTRP2 5.2203 12.4662 1.479 14.4317
EquiPSC Line K2 GDSC2 -2.7824 1.225 -3.8058 23.5281
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FLO-1 GDSC2 -6.7029 -4.5873 -6.7047 66.9521
OACP4 C GDSC2 -5.1133 -0.8942 -5.364 51.1296
HCE-4 GDSC1; GDSC2 -5.0745 -3.2129 -5.0882 40.9492
TE-12 GDSC1; GDSC2 -4.0992 1.8932 -5.4516 36.5964
KYSE-220 GDSC2 -3.9626 1.8977 -4.9585 42.5453
OACM5.1 C GDSC2 -3.3575 1.3801 -4.1158 36.8432
ESO-26 GDSC2 -2.525 5.9528 -5.2749 36.2882
KYSE-50 GDSC2 -0.4374 5.8828 -3.3134 21.2532
ESO-51 GDSC2 0.3915 6.1958 -2.778 15.9625
SK-GT-4 GDSC2 1.6744 6.5933 -2.0273 8.5822
KYAE-1 GDSC2 2.0305 3.7261 -0.5622 0.5384
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 -3.7654 3.3244 -4.1609 57.1132
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-SI9s CTRP2 -16.2201 2.4616 -17.5114 82.2873
NH-6 CTRP2 -9.4447 3.4933 -10.373 74.2485
IMR-32 CTRP2 -8.3419 -7.9416 -8.3419 89.181
SK-N-AS GDSC2; CTRP2 -8.3067 1.2668 -8.6957 75.1547
NB1 GDSC1; GDSC2; CTRP2 -8.104 3.2822 -8.8648 71.9417
Kelly GDSC1; GDSC2; CTRP2 -5.6011 -4.1717 -5.6011 70.9165
SK-N-MC-IXC GDSC2 -5.4107 -3.2232 -5.4341 44.3421
SK-N-BE(2) CTRP2 -5.2302 6.1612 -6.4924 61.2606
IMR-5 GDSC1; GDSC2 -4.9678 -3.5732 -4.9683 49.8487
CHP-212 GDSC2; CTRP2 -4.8944 -1.3989 -4.9006 65.8059
SK-N-DZ GDSC1; GDSC2; CTRP2 -4.8447 -1.8649 -4.8465 65.6839
KP-N-YS GDSC1; GDSC2 -4.749 -2.6264 -4.788 37.8035
MHH-NB-11 GDSC1; GDSC2; CTRP2 -4.5461 -1.2439 -4.5512 59.7912
SiMa GDSC1; GDSC2; CTRP2 -4.2181 -2.2823 -4.2182 61.7
SJNB-13 GDSC1; GDSC2 -4.0582 -1.5271 -4.1243 40.9894
SK-N-BE(2)-M17 GDSC1; GDSC2 -3.895 -2.3386 -3.9007 39.1111
CHP-126 GDSC1; GDSC2; CTRP2 -3.2209 1.976 -3.3603 51.5206
NB69 GDSC1; GDSC2 -3.1425 -1.5264 -3.1627 31.634
GI-ME-N GDSC1; GDSC2 -3.0473 2.8992 -4.4004 36.1768
KP-N-RT-BM-1 GDSC1; GDSC2 -2.9465 1.5189 -4.104 25.7666
TGW GDSC1; GDSC2 -2.9435 -1.8615 -2.946 29.5484
SJNB-17 GDSC1; GDSC2 -2.8111 -0.4144 -3.1625 20.0729
SK-N-SH GDSC2; CTRP2 -2.771 1.7685 -2.863 51.9605
SJNB-6 GDSC1; GDSC2 -1.8948 1.5388 -3.075 15.9464
NB(TU)1 GDSC1; GDSC2 -1.8426 0.2941 -2.0983 19.8538
SJNB-5 GDSC1; GDSC2 -1.6105 -0.0348 -2.0531 8.6842
GOTO GDSC1; GDSC2 -1.429 3.6741 -3.131 23.826
NH-12 GDSC1; GDSC2 -1.1484 2.3946 -2.2508 17.914
SJNB-14 GDSC1; GDSC2 -0.9924 0.0593 -1.0999 10.5276
SJNB-10 GDSC1; GDSC2 -0.8755 0.18 -1.01 9.5069
SJNB-7 GDSC1; GDSC2 -0.5811 0.4764 -0.8067 7.0944
LA-N-6 GDSC1; GDSC2 -0.5436 4.3303 -3.295 13.055
SK-N-FI GDSC1; GDSC2; CTRP2 -0.4128 5.2235 -0.9611 37.8727
SJNB-12 GDSC2 -0.1387 19.1634 -9.6975 36.8792
KP-N-YN GDSC1; GDSC2; CTRP2 4.8881 15.1752 -0.1518 20.8648
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 -5.2958 -0.8034 -5.3217 67.6531
SNU-1079 CTRP2 -2.3639 0.9537 -2.386 49.3638
SNU-1196 CTRP2 -0.205 7.2752 -1.4177 38.1153
HuH-28 CTRP2 0.8657 3.8852 0.7402 28.2634
SNU-869 CTRP2 1.1496 8.9021 -0.6453 31.693
HuCC-T1 GDSC2; CTRP2 1.8724 6.2129 1.2057 23.5068
SNU-308 CTRP2 1.9464 6.2177 1.2835 23.0065
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 88 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-468 GDSC2; CTRP2 -8.3645 6.7444 -10.0864 68.6961
Hs 578T GDSC2; CTRP2 -6.253 5.0128 -7.2761 65.3416
OCUB-M GDSC1; GDSC2 -5.4078 -4.3685 -5.4078 65.6975
HCC1599 GDSC1; GDSC2 -4.6953 -0.5572 -4.7479 55.8373
CAL-51 GDSC2; CTRP2 -4.5447 0.8331 -4.6402 62.5158
HMC-1-8 CTRP2 -4.1941 -1.3378 -4.1962 61.4535
DU4475 GDSC1; GDSC2; CTRP2 -3.9716 -0.6856 -3.9788 59.9103
CAL-148 GDSC1; GDSC2; CTRP2 -3.8433 2.398 -4.0816 57.947
HCC1806 GDSC2; CTRP2 -2.9638 4.4823 -3.5483 52.6901
Evsa-T GDSC1; GDSC2 -2.8609 1.4094 -3.016 46.7524
BT-549 GDSC2; CTRP2 -2.4515 10.9703 -5.2698 49.9663
HCC1143 GDSC2; CTRP2 -2.3944 8.0951 -4.0719 49.7103
MRK-nu-1 GDSC1; GDSC2 -2.3751 2.0907 -2.6077 43.4136
MDA-MB-453 GDSC2; CTRP2 -2.0397 4.0205 -2.4331 47.5426
HCC2157 GDSC1; GDSC2 -1.8365 -0.0408 -1.9932 19.2516
COLO 824 GDSC1; GDSC2 -1.6567 3.4453 -2.1456 38.9227
MCF-7 GDSC2; CTRP2; CTRP1 -1.2002 5.6411 -1.9393 43.0583
JIMT-1 GDSC2; CTRP2 -0.9055 4.5087 -1.3108 40.6344
MDA-MB-231 GDSC2; CTRP2 -0.5917 13.1803 -4.3237 43.3596
EFM-19 GDSC2 -0.4879 26.0861 -11.3726 44.3097
CAL-85-1 GDSC2; CTRP2 -0.366 7.3776 -1.6286 39.1331
Hs 578Bst CTRP2 -0.3457 10.2501 -7.5206 22.8067
HCC38 GDSC2; CTRP2 -0.3229 17.4482 -6.0494 43.8577
HCC1395 GDSC2; CTRP2 -0.1383 8.0978 -1.6628 38.3669
AU565 GDSC2; CTRP2 0.3477 122.7063 -58.8665 48.3551
UACC-893 GDSC2 0.3907 9.6579 -2.5289 30.5343
MDA-MB-361 GDSC2; CTRP2 0.6126 7.7495 -0.7283 33.6318
BT-474 GDSC1; GDSC2; CTRP2 0.7806 9.1803 -1.1468 34.1397
YMB-1-E GDSC2 1.0722 5.8635 -2.8969 7.0656
MDA-MB-157 GDSC2 1.0859 9.1913 -1.635 27.5598
HCC1954 GDSC2; CTRP2 1.3064 17.8837 -4.7057 38.64
HCC1428 GDSC2; CTRP2 1.365 5.127 1.0061 25.7552
EFM-192A GDSC2; CTRP2 1.4025 24.7975 -8.0103 41.371
HCC1569 GDSC2 1.4227 10.8952 -2.1443 26.6301
MDA-MB-330 GDSC2 1.5853 17.562 -5.2925 33.3799
ZR-75-1 CTRP2 1.7793 5.1747 1.4447 22.9223
CAL-120 GDSC2; CTRP2 1.8414 8.6314 0.1846 27.1426
HCC1937 GDSC2; CTRP2 1.9609 5.9854 1.3824 22.6032
HCC2218 GDSC1; GDSC2; CTRP2 2.0635 9.1961 0.1583 25.0675
HCC70 GDSC2 2.162 4.2538 1.7197 10.586
T-47D GDSC2; CTRP2 2.2028 9.898 -0.0239 26.7963
HCC1500 GDSC2; CTRP2 2.249 5.0688 1.987 19.5396
HCC202 CTRP2 2.2671 9.3008 0.3152 25.5188
UACC-812 GDSC2 2.3134 4.304 -0.6626 0.6812
HDQ-P1 GDSC2; CTRP2 2.4355 13.3154 -1.4254 30.0966
MFM-223 GDSC1; GDSC2 2.5526 10.0476 -0.7018 20.2059
HCC1419 GDSC2; CTRP2 2.7441 6.2785 2.115 17.6203
CAMA-1 GDSC2; CTRP2 2.9374 6.0613 2.4048 15.9753
MDA-MB-175-VII GDSC2 2.972 8.0717 0.6495 13.4082
KPL-1 CTRP2 3.1399 4.0273 3.1327 12.7123
BT-483 GDSC2 3.5946 8.6974 0.8579 11.0682
ZR-75-30 GDSC2; CTRP2 3.9445 7.9034 2.6195 12.5297
MDA-MB-415 GDSC2 4.6071 14.0734 -1.0239 16.9154
HCC1187 GDSC1; GDSC2 4.6714 13.5132 -0.6974 15.5504
MDA-MB-436 GDSC2 5.9096 16.8625 -1.4317 15.9952
BT-20 GDSC2; CTRP2 6.2834 58.6167 -20.7164 40.9956
BT 145 CTRP2 -12.2716 6.3914 -14.2375 74.8639
BT 286 CTRP2 -5.0354 6.175 -6.2843 60.6078
BT 245 CTRP2 -3.2292 6.9441 -4.5668 53.4252
BT 179 CTRP2 -3.2277 6.8593 -4.5368 53.4381
BT 172 CTRP2 -3.1122 4.1089 -3.6203 53.5338
BT 428 CTRP2 -2.6456 12.6173 -6.1707 50.6076
BT 504 CTRP2 -2.4742 7.9364 -4.0993 50.0595
BT147 CTRP2 -0.6377 7.8258 -2.0888 40.9585
BT 231 CTRP2 -0.6109 7.3529 -1.8822 40.5189
BT 224 CTRP2 -0.4385 24.6735 -9.6449 45.7389
BT164 CTRP2 0.0993 1148.6408 -570.8799 49.8776
BT 239 CTRP2 0.1638 5.9945 -0.5687 34.7387
BT 248 CTRP2 0.2406 6.4012 -0.6226 34.6154
BT 416 CTRP2 0.2695 14.7218 -4.1828 40.7173
BT 359 CTRP2 0.2717 13.7637 -3.7317 40.1943
BT 159 CTRP2 0.3956 9.938 -1.8723 36.9538
BT 232 CTRP2 0.4864 9.2429 -1.4785 35.849
BT 139 CTRP2 0.4869 5.926 -0.1953 32.5513
BT 482 CTRP2 1.1274 6.5784 0.2708 29.0061
BT 187 CTRP2 2.1746 7.6435 0.9564 23.5429
BT 440 CTRP2 2.2428 5.1056 1.97 19.62
BT 216 CTRP2 2.3279 4.4429 2.2197 18.4682
BT 330 CTRP2 2.4985 3.6046 2.4922 16.9821
BT 228 CTRP2 2.5181 3.1292 2.5181 16.8306
BT 340 CTRP2 2.5964 3.3079 2.5961 16.3097
BT 444 CTRP2 2.6308 4.3558 2.5614 16.3158
BT 131 CTRP2 2.6894 16.7075 -2.8498 32.5472
BT 333 CTRP2 2.7204 12.3503 -0.6889 27.4224
BT 498 CTRP2 2.9056 4.664 2.8021 14.6048
BT 422 CTRP2 3.5156 4.6031 3.4725 10.3318
BT 328 CTRP2 3.9485 4.8135 3.9027 7.458
BT 320 CTRP2 4.7626 5.6153 4.4999 2.8978
⏷ Show the Full List of 88 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -1.646 3.1316 -1.8378 44.9129
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-60 CTRP2 -8.459 -6.8882 -8.459 89.4154
Hs 683 GDSC2; CTRP2 -7.1357 6.7969 -8.7649 64.2217
YH-13 GDSC2; CTRP2 -6.4166 7.0183 -8.0532 64.0648
M059K CTRP2 -6.2394 8.7056 -8.4335 62.3939
Daoy GDSC2; CTRP2 -6.2139 -4.6342 -6.2139 74.9788
MOG-G-UVW GDSC2 -5.9855 -0.1099 -6.5025 57.3213
D283 Med GDSC1; GDSC2; CTRP2 -5.8371 -4.3425 -5.8371 72.484
Becker GDSC1; GDSC2; CTRP2 -5.5313 -2.8479 -5.5317 70.2456
GI-1 GDSC1; GDSC2 -5.4226 -0.8565 -5.7079 53.6722
H4 GDSC2 -5.2206 -2.5127 -5.2557 52.3061
GaMG GDSC2; CTRP2; CTRP1 -4.9095 14.924 -9.4999 56.4018
D-423MG GDSC2 -4.6415 0.0895 -5.3172 39.0815
D-566MG GDSC2 -4.264 -2.0405 -4.3413 33.1363
TM-31 CTRP2 -4.1603 29.8884 -15.6888 52.6871
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -4.0641 -2.2245 -4.0771 40.8387
A-172 GDSC2; CTRP2 -3.9629 5.3311 -4.8653 57.0688
LN-18 GDSC2; CTRP2 -3.623 -1.0877 -3.6242 57.716
SF268 GDSC1; GDSC2; CTRP2 -3.4201 1.2096 -3.4947 56.0278
MOG-G-CCM GDSC2 -3.344 4.7368 -5.5173 40.4057
D-336MG GDSC1; GDSC2 -3.1994 3.0193 -5.0448 31.0435
SK-MG-1 GDSC2 -2.8007 1.1868 -3.4464 31.2839
AM-38 GDSC1; GDSC2; CTRP2 -2.6067 4.3708 -3.1317 50.8055
KINGS-1 GDSC1; GDSC2 -2.5305 3.339 -4.0642 32.5681
KALS-1 GDSC1; GDSC2; CTRP2 -1.7607 7.9973 -3.3556 46.7929
SF539 GDSC1; GDSC2 -1.6501 1.4395 -2.3272 20.322
LN-229 GDSC2; CTRP2; CTRP1 -1.6092 3.2103 -1.8096 44.7431
M059J GDSC2 -1.4915 7.0938 -4.8555 31.1277
LNZTA3WT4 GDSC2 -1.2778 3.2998 -2.8066 21.5501
SF126 GDSC1; GDSC2; CTRP2 -1.1684 3.2002 -1.3359 39.2517
8-MG-BA GDSC1; GDSC2; CTRP2 -1.0051 9.9042 -3.3119 43.8333
D-247MG GDSC1; GDSC2 -0.717 5.5018 -4.0181 17.552
U-251MG GDSC2; CTRP2 -0.6651 5.7401 -1.3896 39.8171
SW1783 GDSC2 -0.6163 10.2548 -5.6497 30.6151
YKG-1 GDSC2; CTRP2 -0.5893 45.1656 -19.885 47.191
Onda 10 GDSC1; GDSC2 -0.5188 7.9383 -5.0748 21.9555
D-542MG GDSC2 -0.5121 8.9763 -5.5876 23.9689
42-MG-BA GDSC2; CTRP2 -0.4484 7.9792 -1.9459 40.0136
KNS-81-FD GDSC1; GDSC2 -0.3127 2.9851 -2.4528 7.3701
KG-1-C CTRP2 -0.2078 3.176 -0.3063 35.3063
D-245MG GDSC2 -0.1467 5.2333 -3.4372 12.8266
Onda 11 GDSC1; GDSC2 0.2535 5.6068 -3.326 11.2145
KNS-42 GDSC1; GDSC2; CTRP2 0.2996 11.2241 -2.5397 36.6882
D-502MG GDSC1; GDSC2 0.3014 4.9857 -2.9899 9.1727
DK-MG GDSC2; CTRP2 0.3369 6.9655 -0.7211 34.5438
SF295 GDSC2; CTRP2 0.4831 7.8256 -0.8958 32.5709
SNU-466 CTRP2 0.5568 3.4086 0.4775 30.1624
ONS-76 GDSC1; GDSC2; CTRP2 0.6073 8.1924 -0.9126 34.1253
SNB-75 GDSC1; GDSC2; CTRP2 0.7486 8.4886 -0.8867 31.7503
D-392MG GDSC2 0.8099 4.2337 -1.4857 7.2815
D-263MG GDSC1; GDSC2 0.837 6.6168 -2.6394 13.9982
GB-1 GDSC1; GDSC2; CTRP2 0.8706 6.3679 0.0699 30.4684
SNU-626 CTRP2 0.9715 11.4029 -1.9443 35.3043
CAS-1 GDSC1; GDSC2; CTRP2 1.0844 8.7011 -0.6265 31.8437
LN-405 GDSC2 1.4674 9.4775 -3.5783 17.1745
SNU-738 CTRP2 1.8017 19.0372 -4.8093 37.6094
SNU-1105 CTRP2 1.8942 9.172 -0.002 27.5887
SNU-489 CTRP2 2.0023 10.9463 -0.7104 29.3847
U-87MG ATCC GDSC1; CTRP2 2.0722 7.3184 0.9862 23.7241
SNU-201 CTRP2 2.6782 5.3461 2.3738 16.8412
SW1088 GDSC2; CTRP2 2.8817 16.8819 -2.7609 31.9302
KNS-81 CTRP2 3.3138 4.0093 3.3112 11.5382
T98G GDSC2; CTRP2 3.5269 15.4013 -1.4473 27.5152
NMC-G1 GDSC1; GDSC2; CTRP2 3.5351 4.2825 3.5272 9.4524
CCF-STTG1 CTRP2 4.2866 11.2079 1.3104 16.9956
GMS-10 CTRP2 4.9727 37.225 -11.1057 37.8512
GOS-3 CTRP2 6.4198 28.0378 -5.3272 29.6591
U-118MG GDSC2; CTRP2 9.0634 27.419 -2.996 21.3538
DBTRG-05MG GDSC2; CTRP2 9.1749 30.7578 -4.5534 24.3208
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 -3.16 5.8421 -5.8429 40.1859
TGBC24TKB GDSC1; GDSC2 -2.4294 1.5788 -3.2029 28.3747
TGBC1TKB GDSC1; GDSC2 1.9943 3.5696 -0.5188 0.4322
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-7 CTRP2 -10.9643 3.8485 -12.1149 76.0675
MFE-319 GDSC2; CTRP2 -8.34 7.6404 -10.3457 67.837
HEC-151 CTRP2; CTRP1 -6.9059 1.8471 -7.2828 70.8139
HEC-50B CTRP2 -6.1068 37.2431 -21.0846 54.5527
RL95-2 GDSC1; GDSC2; CTRP2 -5.6874 -4.4473 -5.6874 71.4946
AN3-CA GDSC2; CTRP2 -5.6367 11.4256 -8.8134 59.3925
JHUEM-1 CTRP2 -4.7244 4.732 -5.5329 60.4695
JHUEM-3 CTRP2 -4.4128 5.9166 -5.5273 58.5539
HEC-1-A CTRP2 -4.3235 4.262 -4.9766 59.1612
JHUEM-2 CTRP2; CTRP1 -3.865 0.2921 -3.8985 59.0158
HEC-265 CTRP2 -3.4622 3.0368 -3.7782 55.6797
HEC-1-B CTRP2 -2.8362 3.9443 -3.2824 52.0968
HEC-6 CTRP2 -1.9285 4.7446 -2.4856 47.009
MFE-296 GDSC2; CTRP2 -1.5662 4.6022 -2.0542 44.821
KLE GDSC1; GDSC2; CTRP2; CTRP1 -1.2213 6.2806 -2.1635 43.4601
ESS-1 GDSC2; CTRP2 -0.9268 20.0264 -7.8616 46.1814
HEC-59 CTRP2; CTRP1 -0.7629 7.1169 -1.9554 41.2783
HEC-251 CTRP2 -0.76 6.4124 -1.7103 40.8058
EFE-184 CTRP2 0.6502 4.3779 0.4131 30.0706
MFE-280 GDSC2 1.7 5.8939 -1.6793 6.5442
EN GDSC2; CTRP2 4.1633 5.4628 3.9432 6.6709
HEC-108 CTRP2; CTRP1 4.5697 10.6666 1.8376 14.4029
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 -5.0935 -2.8119 -5.0936 67.5086
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW13 GDSC2 -5.327 -2.6479 -5.3575 53.3416
KTCTL-140 GDSC2 -3.4334 -0.2616 -3.8885 26.8041
BB65-RCC GDSC1; GDSC2 -2.9325 0.5905 -3.6853 23.5026
RXF 393L GDSC1; GDSC2 -2.8242 2.1287 -4.2596 26.0326
TUHR4TKB CTRP2 -2.1922 10.4941 -4.8007 48.9778
KTCTL-13 GDSC2 -2.149 0.8868 -3.0144 16.5181
KTCTL-21 GDSC2 -1.9615 1.7278 -3.2296 17.1065
769-P GDSC2; CTRP2 -1.7107 2.8232 -1.8614 45.2653
BFTC-909 GDSC2; CTRP2 -1.1651 7.5946 -2.5667 43.6743
NCC010 GDSC2 -1.0913 2.7927 -2.973 12.6935
LB2241-RCC GDSC1; GDSC2 -0.9221 7.6519 -5.2612 23.8765
VMRC-RCZ GDSC2; CTRP2 -0.8587 5.4944 -1.5261 40.8699
HA7-RCC GDSC1; GDSC2 -0.7563 5.0865 -3.8427 16.7342
KTCTL-26A GDSC2 -0.7092 1.8839 -2.2074 6.8379
LB1047-RCC GDSC1; GDSC2 -0.695 3.5585 -3.0303 11.8989
KTCTL-1M GDSC2 -0.308 4.821 -3.3558 12.7787
786-O GDSC2; CTRP2 -0.129 4.1257 -0.3797 35.2498
SW156 GDSC2 -0.0789 4.0017 -2.781 8.811
CAL-54 GDSC2; CTRP2 -0.0531 6.3155 -0.9112 36.4079
NCC021 GDSC2 0.2133 3.8422 -2.4998 6.4748
LB996-RCC GDSC1; GDSC2 0.2491 7.8365 -3.7126 21.0365
A-498 GDSC1; GDSC2 0.2686 3.2059 -1.3849 8.0113
KTCTL-195 GDSC2 0.3383 5.8543 -2.6503 15.4097
SNU-1272 CTRP2 0.3932 11.5787 -2.605 38.2579
VMRC-RCW GDSC2; CTRP2 0.422 4.7878 0.0676 29.9889
A-704 GDSC1; GDSC2 0.9023 4.7535 -1.6731 8.2042
TK-10 GDSC1; GDSC2 0.9784 6.2517 -2.3526 12.0297
UO-31 GDSC2; CTRP2 1.2201 4.5001 1.0059 24.5779
SN12C GDSC2 1.9874 3.7101 -0.5739 0.6003
KMRC-20 GDSC2; CTRP2 2.0243 8.2697 0.5308 25.4647
KMRC-3 CTRP2 2.2647 6.6633 1.4545 21.4591
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 2.3308 10.6848 -0.2586 27.2363
KMRC-2 CTRP2 3.3636 7.4624 2.2543 15.4243
OS-RC-2 GDSC1; GDSC2; CTRP2 4.1694 9.8805 1.8633 15.0866
KMRC-1 GDSC2; CTRP2 4.212 12.994 0.3563 20.6174
Caki-2 CTRP2 4.3752 9.9687 2.0045 14.0701
Caki-1 GDSC2; CTRP2 4.5828 13.4631 0.4445 18.4481
ACHN GDSC2; CTRP2 4.6964 11.5517 1.4964 15.4108
TUHR10TKB CTRP2 5.1466 7.6659 3.8178 4.962
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GP2d CTRP2 -8.995 11.7377 -12.5121 65.9109
CCK-81 GDSC2; CTRP2 -8.9918 6.3184 -10.6397 70.2784
KM12 GDSC1; GDSC2; CTRP2; CTRP1 -8.1741 9.3245 -10.7373 66.1752
CL-34 CTRP2; CTRP1 -8.0222 1.2495 -8.3863 74.564
SW48 GDSC2; CTRP2 -6.6035 -0.0308 -6.723 72.3939
SNU-C2B GDSC1; GDSC2 -6.3745 -3.1101 -6.4146 62.893
SNU-1040 CTRP1 -6.3276 3.3772 -6.952 84.7347
SW948 GDSC2; CTRP2; CTRP1 -6.0449 13.6885 -10.1581 59.3475
NCI-H508 GDSC2; CTRP2; CTRP1 -5.7121 4.7827 -6.6215 61.6241
SNU-283 GDSC2 -5.4702 -3.1286 -5.5019 44.9576
SNU-C2A CTRP2 -5.1529 1.1658 -5.3141 65.1869
GP5d GDSC2 -5.0861 -3.5045 -5.0873 51.0375
SNU-175 GDSC2; CTRP2; CTRP1 -4.8331 1.3408 -4.9946 63.5925
HCC2998 GDSC2 -4.5694 -1.2809 -4.7045 46.1445
SNU-407 GDSC2; CTRP2 -4.2925 3.6275 -4.7962 59.4177
LoVo GDSC2; CTRP2; CTRP1 -4.1056 2.757 -4.4213 59.1109
LS180 GDSC2; CTRP2; CTRP1 -3.9932 -1.2443 -3.995 60.1839
HT115 GDSC2; CTRP2; CTRP1 -3.7567 -1.0612 -3.7586 54.9998
SNU-C5 GDSC2; CTRP2; CTRP1 -3.2056 5.808 -4.1756 53.6187
CaR-1 GDSC2 -3.1762 3.5093 -4.7982 37.9688
SNU-503 CTRP2 -2.9107 23.6387 -11.4981 50.9022
SNU-61 GDSC2; CTRP2; CTRP1 -2.2374 3.8116 -2.6012 48.7384
COLO 320HSR GDSC1; GDSC2 -2.2312 -0.6019 -2.301 22.7468
DiFi GDSC2 -2.1157 2.8536 -3.4259 28.0492
SNU-81 GDSC2; CTRP2; CTRP1 -2.04 4.2617 -2.4861 44.9684
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 -1.6785 5.5299 -2.4277 45.7975
T84 GDSC2 -1.5347 2.5934 -2.7243 22.0883
SW620 GDSC2; CTRP2; CTRP1 -1.4891 7.0583 -2.7181 42.9635
COLO205 GDSC2; CTRP2 -1.4623 4.5566 -1.9295 44.1701
SNU-C4 CTRP2; CTRP1 -1.1133 5.024 -1.6675 42.2502
SW837 GDSC2 -1.0993 5.1132 -3.522 24.5078
LS513 GDSC1; GDSC2; CTRP2 -1.0876 2.0272 -1.1246 40.9586
LS411N GDSC1; GDSC2; CTRP2 -1.0767 3.1789 -1.2344 41.185
HCT 15 GDSC2; CTRP2 -1.048 2.6187 -1.1325 40.8203
NCI-H747 GDSC1; GDSC2; CTRP2 -0.9632 4.1989 -1.3018 40.8566
SW1463 GDSC2 -0.8338 6.862 -4.1484 26.2938
CL-11 GDSC1; GDSC2; CTRP2 -0.8337 4.0532 -1.1297 39.9374
NCI-H716 GDSC1; GDSC2; CTRP2 -0.817 7.3486 -2.1021 41.6723
HCT 116 GDSC2; CTRP2; CTRP1 -0.5022 3.1519 -0.6157 37.3597
OUMS-23 CTRP2 -0.4048 3.5594 -0.5727 36.8158
SNU-1033 CTRP2 0.086 5.4704 -0.4889 34.7929
HT-55 GDSC2; CTRP2; CTRP1 0.1353 7.734 -1.2243 36.5284
SNU-C1 GDSC1; GDSC2; CTRP2 0.1665 5.623 -0.4476 34.3916
RKO GDSC1; GDSC2; CTRP2; CTRP1 0.185 20.0216 -6.7912 43.1293
COLO 320 CTRP2; CTRP1 0.3309 11.5963 -2.6695 38.5954
RCM-1 [Human ESC] GDSC2; CTRP2; CTRP1 0.3399 5.3271 -0.1668 33.0281
CL-40 CTRP1 0.3575 7.3406 -0.8356 58.5223
LS1034 GDSC1; GDSC2; CTRP2 0.6819 6.5953 -0.2149 31.9587
SW626 GDSC2 0.7394 6.2507 -2.5325 13.6591
SW1417 GDSC2; CTRP2 0.7985 5.7421 0.2029 30.2768
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 0.8499 5.9297 0.2013 30.1806
SW1116 GDSC2; CTRP2 0.9444 6.4946 0.1043 30.1222
HCT 8 CTRP2; CTRP1 1.1358 3.2306 1.1052 26.2137
C2BBe1 GDSC1; GDSC2; CTRP2 1.4934 5.1308 1.1452 24.8673
COLO 678 GDSC2; CTRP2; CTRP1 1.5957 6.917 0.6484 26.3731
DLD-1 CTRP2 1.83 10.3705 -0.6128 29.5937
SK-CO-1 GDSC2; CTRP2 2.0339 8.3338 0.5127 25.4994
SW480 CTRP1 2.424 10.2231 0.0498 44.3789
HT-29 GDSC2; CTRP2; CTRP1 2.7902 5.6829 2.3883 15.507
LS123 GDSC1; GDSC2; CTRP2; CTRP1 2.9591 12.3987 -0.4802 26.2755
HCC-56 CTRP2 3.4821 11.5865 0.3949 22.1507
⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 1.5233 3.763 -0.8149 2.0705
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-5 CTRP2 -8.5709 7.0245 -10.3987 68.8288
HLF CTRP2 -5.0944 6.4673 -6.4393 60.6109
SNU-182 CTRP2 -4.0483 4.0382 -4.6232 58.0898
PLC/PRF/5 CTRP2 -3.9948 4.0664 -4.5715 57.8335
Li-7 CTRP2 -3.7022 1.1051 -3.7811 57.727
HuH-1 GDSC2; CTRP2 -3.2832 6.815 -4.5823 53.6832
SNU-878 CTRP2 -3.1143 -0.2092 -3.1199 54.3237
HLE GDSC2 -2.1566 2.6134 -3.3599 27.9161
JHH-4 GDSC2; CTRP2 -2.143 2.0172 -2.2262 47.9626
SNU-398 GDSC2; CTRP2; CTRP1 -1.9764 31.8485 -14.5717 49.2404
HuH-6 CTRP2 -1.9604 4.2292 -2.394 47.103
Hep 3B2.1-7 GDSC2; CTRP2 -0.5727 6.5273 -1.5463 37.5612
SK-HEP-1 GDSC2; CTRP2 -0.4671 13.5059 -4.3472 43.0025
JHH-7 GDSC2 -0.1889 6.5151 -3.4163 20.9673
SNU-387 GDSC2; CTRP2 -0.0207 10.6965 -2.6318 39.6163
SNU-423 GDSC2; CTRP2 -0.0135 7.5376 -1.3118 37.196
Hep-G2 CTRP2; CTRP1 0.0035 6.8005 -1.0157 36.5126
SNU-761 CTRP2 0.4902 6.1411 -0.2633 32.7423
SNU-475 CTRP2 0.7152 13.7686 -3.298 38.3592
Huh-7 GDSC2 1.7232 4.4771 -1.018 2.8343
SNU-449 GDSC2; CTRP2; CTRP1 1.9303 5.9298 1.3725 22.8034
JHH-1 GDSC2; CTRP2 2.1321 4.1383 2.0598 19.6479
Hep-G2/C3A GDSC2 2.1509 3.7073 -0.5078 0.3333
JHH-2 GDSC2; CTRP2 2.588 14.7917 -2.0022 31.0563
SNU-886 CTRP2 3.286 19.8075 -3.8493 32.9868
JHH-6 GDSC2; CTRP2; CTRP1 4.5374 4.8588 4.5293 3.4982
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 227 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2286 CTRP2; CTRP1 -13.6027 13.0804 -17.9479 70.922
NCI-H1341 GDSC2; CTRP2 -12.1907 4.5832 -13.6409 76.6796
NCI-H1792 GDSC2; CTRP2 -10.9119 36.9079 -25.5663 59.4972
LUDLU-1 CTRP2 -10.4745 11.1626 -13.8834 68.5314
SCLC-21H CTRP2; CTRP1 -10.1855 1.2725 -10.718 78.4831
NCI-H2122 GDSC2; CTRP2; CTRP1 -9.6173 8.6983 -12.081 69.1743
COR-L279 GDSC2; CTRP2 -9.154 6.5297 -10.8805 70.3549
DV-90 CTRP2 -8.8796 -0.1861 -9.1074 78.6331
LK2 CTRP2 -8.3597 -8.095 -8.3597 89.3002
NCI-H146 GDSC2; CTRP2 -8.3316 -2.5077 -8.3655 78.4417
DMS 53 GDSC2; CTRP2 -7.7756 2.4179 -8.3268 72.3182
NCI-H522 GDSC2; CTRP2 -7.5949 2.3386 -8.1159 71.987
COR-L47 CTRP2 -7.3426 21.1452 -14.7406 59.0606
NCI-H2073 CTRP1 -7.2676 9.397 -9.7855 75.8687
COR-L311 GDSC2 -7.1031 -1.047 -7.4931 64.9226
NCI-H1703 GDSC2; CTRP2 -7.0332 -4.3673 -7.0333 79.7724
COR-L51 CTRP2; CTRP1 -6.8455 5.4053 -8.0289 66.6064
NCI-H211 GDSC1; GDSC2; CTRP2 -6.2801 -4.2652 -6.2801 75.3369
HARA [Human squamous cell lung carcinoma] GDSC2; CTRP2 -6.1941 -1.4479 -6.2178 72.6374
LC-2/ad GDSC1; GDSC2 -6.194 -2.7806 -6.3 51.9567
MOR/CPR CTRP2 -6.097 -5.0767 -6.097 74.2248
NCI-H810 GDSC2; CTRP2 -6.0235 3.1772 -6.5805 66.4653
NCI-H322 CTRP2 -5.7857 12.4602 -9.3862 59.2785
NCI-H1339 CTRP2 -5.7019 7.7805 -7.5301 61.5836
NCI-H446 GDSC1; GDSC2; CTRP2 -5.6822 -2.1557 -5.6862 70.7589
NCI-H1184 CTRP2 -5.625 3.7813 -6.2804 64.52
Lu-135 GDSC2 -5.6102 3.3673 -7.2849 53.4212
SBC-5 GDSC2; CTRP2 -5.5174 -4.366 -5.5174 70.3637
NCI-H82 GDSC1; GDSC2 -5.5167 -2.5537 -5.5611 55.0904
LC-1/sq GDSC2 -5.4973 -3.1003 -5.5114 55.0561
NCI-H838 GDSC2; CTRP2 -5.3708 -2.1979 -5.3729 64.8778
A-549 GDSC2; CTRP2 -5.2712 3.6954 -5.8758 63.3361
HCC1438 CTRP2 -5.248 17.0128 -10.7669 56.5437
NCI-H524 GDSC1; GDSC2; CTRP2 -5.2473 2.2418 -5.5649 64.5716
A-427 GDSC2 -5.2444 -3.3713 -5.256 42.6408
NCI-H1437 GDSC2 -5.1871 -1.7054 -5.398 42.7016
NCI-H1048 GDSC2 -5.1202 -3.3983 -5.1225 51.3774
PC-14 GDSC2; CTRP2 -5.0264 -1.4734 -5.0328 62.6719
LB647-SCLC GDSC1; GDSC2 -4.9803 -3.6003 -4.9825 39.953
HCC95 CTRP2 -4.9731 3.4615 -5.5 62.3929
NCI-H526 GDSC1; GDSC2; CTRP2 -4.9101 0.7463 -5.0156 64.4214
NCI-H847 GDSC1; GDSC2 -4.8634 -2.9144 -4.8708 48.8098
Ms-1 GDSC1; GDSC2 -4.8372 -2.7419 -4.849 48.5535
NCI-H661 GDSC2; CTRP2 -4.8099 -0.9229 -4.8233 65.0729
NCI-H510A GDSC1; GDSC2 -4.7983 -3.8698 -4.7984 38.117
VMRC-LCD GDSC2; CTRP2 -4.7751 5.997 -5.9464 59.8266
NCI-H2227 GDSC2 -4.7506 0.9534 -5.7536 40.878
NCI-H1975 GDSC1; GDSC2; CTRP2 -4.6385 -1.4322 -4.6423 64.2724
LCLC-97TM1 GDSC2; CTRP2 -4.6212 3.9854 -5.2348 60.5793
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 -4.5472 -0.2776 -4.5747 63.2553
RERF-LC-Sq1 GDSC2 -4.5288 -0.084 -4.9197 46.1664
NCI-H1581 GDSC1; GDSC2; CTRP2 -4.5173 -0.7545 -4.5301 63.2802
NCI-H1963 GDSC1; GDSC2; CTRP1 -4.4534 2.7947 -4.8032 60.7228
RERF-LC-MS GDSC2; CTRP2 -4.4127 5.6955 -5.4613 56.3361
NCI-H2009 GDSC2; CTRP2; CTRP1 -4.3851 -0.6182 -4.399 62.4709
NCI-H2087 GDSC2; CTRP2 -4.3319 3.4811 -4.8077 59.6853
NCI-H23 GDSC1; GDSC2; CTRP2 -4.3086 -0.8564 -4.3167 62.0559
LCLC-103H GDSC2; CTRP2 -4.1861 -0.5079 -4.1996 61.1922
NCI-H1651 GDSC2; CTRP2 -4.1801 2.9659 -4.5408 59.31
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 -4.1389 0.8906 -4.2198 60.3394
NCI-H2171 GDSC1; GDSC2; CTRP2 -4.0516 0.2573 -4.0892 56.5789
HCC2279 CTRP2 -4.0401 3.9354 -4.5905 58.1081
NCI-H841 GDSC2; CTRP2; CTRP1 -4.0388 6.3875 -5.2619 56.9202
NCI-H3122 GDSC2 -4.0252 2.9757 -5.4532 43.7464
HCC44 GDSC2; CTRP2 -4.0009 2.9927 -4.3521 58.435
CPC-N GDSC1; GDSC2 -3.9975 0.7427 -4.5859 41.9448
SHP-77 GDSC1; GDSC2; CTRP2 -3.877 -2.829 -3.877 59.4354
NCI-H1304 GDSC1 -3.7688 -0.4166 -4.4986 27.314
HCC33 GDSC1; GDSC2 -3.6684 0.4792 -4.4168 30.5099
NCI-H1734 GDSC2; CTRP2 -3.5575 2.179 -3.7443 53.3954
Lu-139 GDSC1; GDSC2 -3.422 3.4194 -5.0121 39.7191
NCI-H1155 GDSC1; GDSC2; CTRP2 -3.3665 -1.1006 -3.3671 56.0251
Lu-99 CTRP2 -3.0725 5.6877 -3.9975 52.9964
IST-SL1 GDSC1; GDSC2 -3.0612 1.1302 -4.0495 25.9773
HCC15 GDSC2; CTRP2; CTRP1 -2.9932 3.2402 -3.3073 53.1154
NCI-H1944 GDSC2; CTRP2 -2.9584 4.7186 -3.6025 52.6208
NCI-H1105 GDSC2; CTRP2; CTRP1 -2.8795 18.5747 -9.0799 49.8215
NCI-H69 GDSC1; GDSC2; CTRP2 -2.7968 4.104 -3.2757 51.8626
NCI-H1436 GDSC1; GDSC2 -2.7872 1.162 -3.7826 23.4226
NCI-H520 GDSC2; CTRP2 -2.755 4.2095 -3.2547 51.6243
NCI-H187 GDSC1 -2.6898 5.3571 -6.2469 30.5967
ABC-1 GDSC2 -2.6764 2.4971 -4.2864 25.5665
LOU-NH91 GDSC2; CTRP2 -2.5815 5.6393 -3.4478 50.6142
Calu-6 GDSC1; GDSC2; CTRP2 -2.5327 3.4538 -2.8511 50.4223
NCI-H2804 GDSC2 -2.5139 6.6703 -6.1599 32.1387
NCI-H1355 GDSC1; GDSC2; CTRP2 -2.4057 7.112 -3.7318 49.7439
Lu-134-A GDSC1; GDSC2 -2.375 3.8525 -4.6496 26.101
NCI-H1648 GDSC1; GDSC2 -2.2672 7.1004 -5.5802 36.0131
EBC-1 GDSC2; CTRP2 -2.0993 3.6174 -2.4136 47.8478
NCI-H1299 GDSC2; CTRP2 -2.081 2.6815 -2.2372 47.6249
SBC-3 GDSC2 -2.0088 5.4145 -4.5212 31.9821
NCI-H1876 GDSC1; GDSC2; CTRP1 -2.0085 7.1272 -3.3036 47.8748
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 -1.9809 8.4953 -3.775 45.846
EPLC-272H GDSC2; CTRP2 -1.9784 10.9677 -4.7745 48.1926
NCI-H596 GDSC2; CTRP1 -1.9738 1.1485 -1.9938 46.8426
HCC1588 CTRP2 -1.9511 3.1842 -2.1744 46.8696
EMC-BAC-2 GDSC2 -1.9224 1.8061 -2.7662 23.8983
CAL-12T GDSC2; CTRP2; CTRP1 -1.8294 6.3133 -2.8351 44.4512
NCI-H1573 GDSC2; CTRP2 -1.8121 5.3024 -2.5103 46.4576
DMS 273 GDSC2; CTRP2 -1.8086 8.7512 -3.6945 47.1647
Lu-65 GDSC1; GDSC2; CTRP2 -1.7978 3.9042 -2.1451 46.0518
RERF-LC-A1 CTRP2 -1.7841 5.9403 -2.6704 46.45
HCC2108 CTRP2; CTRP1 -1.7452 5.2386 -2.4164 46.1016
DMS 114 GDSC1; GDSC2; CTRP2 -1.6464 4.4917 -2.1143 45.2752
SK-LU-1 CTRP2; CTRP1 -1.6171 6.1984 -2.5671 45.6431
HCC827 GDSC2; CTRP2; CTRP1 -1.5949 4.0693 -1.9583 44.8831
NCI-H2106 CTRP2 -1.5337 6.5582 -2.5983 45.2584
COR-L303 GDSC2 -1.259 8.5909 -6.013 27.6141
NCI-H2135 GDSC1; GDSC2 -1.2586 3.3596 -3.3989 15.75
NCI-H2228 GDSC2; CTRP2 -1.1375 7.7211 -2.5841 43.5831
NCI-H2030 GDSC2; CTRP2; CTRP1 -1.0995 9.4949 -3.2363 42.1755
SW1271 GDSC2; CTRP2 -0.9799 4.3077 -1.3446 41.0169
NCI-H2029 GDSC2; CTRP2 -0.9763 8.1281 -2.5662 40.8215
IST-SL2 GDSC1; GDSC2 -0.9351 6.498 -4.6951 21.5001
NCI-H650 GDSC2; CTRP2 -0.9034 5.8456 -1.6818 41.3384
NCI-H290 GDSC2 -0.7386 3.4637 -3.0179 11.9448
NCI-H1666 GDSC1; GDSC2; CTRP2 -0.7339 3.8987 -0.9898 39.1989
NCI-H1373 CTRP2 -0.7192 14.6965 -5.1466 44.3478
NCI-H647 GDSC2; CTRP2 -0.7033 9.6008 -2.8696 40.3292
NCI-H1770 GDSC1; GDSC2 -0.6614 0.7122 -1.5929 2.8765
NCI-H1793 GDSC2; CTRP2 -0.613 9.641 -2.7919 41.857
NCI-H1693 GDSC2; CTRP2 -0.5811 4.9513 -1.0697 38.7852
NCI-H460 GDSC2; CTRP2; CTRP1 -0.5719 7.6139 -1.9335 38.3882
NCI-H2170 GDSC2; CTRP2 -0.4878 8.8891 -2.35 40.802
NCI-H720 GDSC1; GDSC2 -0.4548 10.63 -5.6986 30.2681
NCI-H322M GDSC1; GDSC2 -0.4215 1.3012 -1.0283 7.8486
NCI-H209 GDSC1; GDSC2; CTRP2 -0.3654 16.6768 -5.7248 43.7586
HCC1833 CTRP2; CTRP1 -0.3337 6.7652 -1.3669 38.5395
NCI-H2172 GDSC2; CTRP2; CTRP1 -0.2933 7.7144 -1.6738 36.929
NCI-H2869 GDSC2 -0.2798 3.8016 -2.8302 9.5955
NCI-H2405 GDSC2; CTRP2 -0.273 4.8645 -0.7105 36.7061
NCI-H1930 CTRP1 -0.2629 6.8152 -1.3082 62.638
NCI-H889 CTRP2 -0.2596 54.333 -24.1486 47.8034
SK-MES-1 GDSC2; CTRP2 -0.2349 5.4092 -0.8207 36.8506
NCI-H2795 GDSC2 -0.2084 4.2318 -2.292 14.9671
COR-L105 GDSC2; CTRP2 -0.2064 5.0299 -0.682 36.3828
NCI-H2373 GDSC2 -0.1505 13.0969 -6.6742 31.8504
SBC-1 GDSC1; GDSC2 -0.1413 5.0593 -3.3472 12.2998
UMC-11 GDSC2 -0.1169 5.2165 -2.7063 17.0601
NCI-H358 GDSC2; CTRP2 -0.0793 8.2656 -1.6669 38.1645
COR-L23 GDSC2; CTRP1 -0.0495 5.4536 -0.6286 35.7251
NCI-H1993 GDSC2 -0.0296 3.9242 -1.9868 12.5939
NCI-H250 GDSC2 -0.0005 8.8504 -5.119 20.7409
LK-2 GDSC2 0.0308 33.3698 -16.6593 41.8851
HCC366 GDSC2; CTRP2 0.1745 5.9208 -0.533 32.5484
RERF-LC-KJ GDSC2; CTRP1 0.1892 5.334 -0.3331 34.0453
Lu-99A GDSC2 0.2365 7.5249 -3.5672 20.405
COR-L88 GDSC1; GDSC2; CTRP2 0.2541 10.7997 -2.3965 38.3541
COR-L321 GDSC2 0.2948 4.3087 -2.6682 7.2995
HOP-92 GDSC2; CTRP2 0.3068 6.3763 -0.5424 34.1664
NCI-H1836 GDSC1; GDSC2; CTRP1 0.3331 5.7568 -0.3047 31.4529
COR-L32 GDSC2 0.3969 13.7846 -7.2628 26.966
HOP-62 GDSC1; GDSC2; CTRP2 0.4135 4.3157 0.1693 31.6587
NCI-H2810 GDSC2 0.4415 7.7697 -4.2492 15.6643
NCI-H2731 GDSC2 0.4417 5.4437 -2.3631 13.4912
NCI-H345 GDSC1; GDSC2 0.4428 6.7378 -3.7423 13.0594
HCC78 GDSC2; CTRP2 0.4441 7.3456 -0.7496 34.2524
NCI-H1435 GDSC2; CTRP2; CTRP1 0.4471 6.2017 -0.3268 33.1357
NCI-H748 GDSC1; GDSC2 0.5437 9.3338 -4.9436 18.6246
NCI-H1650 GDSC1; GDSC2; CTRP2 0.5654 5.5158 0.02 31.6267
NCI-H1092 GDSC1; GDSC2 0.5791 8.971 -4.0126 21.4195
NCI-H2369 GDSC2 0.6497 4.1854 -1.579 8.238
T3M-10 CTRP2; CTRP1 0.6582 9.3453 -1.3387 35.0325
NCI-H2803 GDSC2 0.6623 3.6899 -2.1472 3.6171
ChaGo-K-1 GDSC2; CTRP2 0.7404 4.9371 0.3762 28.0496
NCI-H128 GDSC1 0.7776 2.471 -2.5109 0.2702
EMC-BAC-1 GDSC2 0.9099 7.5442 -3.8041 12.3222
NCI-H1915 GDSC2; CTRP2; CTRP1 0.919 16.5146 -4.4015 39.273
NCI-H2291 GDSC2; CTRP2 0.9408 4.237 0.7578 26.2182
DMS 79 GDSC1; GDSC2 0.9655 7.8072 -3.8926 12.6576
BEN GDSC2; CTRP2 0.9663 1.9812 0.9661 25.4737
NCI-H740 GDSC2 1.0025 9.1173 -4.5024 15.5638
EKVX GDSC1; GDSC2; CTRP2 1.0334 7.359 -0.1273 28.7656
Calu-3 GDSC2; CTRP2 1.0535 4.5954 0.8029 27.4435
DMS 454 CTRP2 1.0955 4.7216 0.8185 27.256
NCI-H513 GDSC2 1.1414 6.6777 -2.4419 12.1362
Sq-1 CTRP2; CTRP1 1.1795 3.809 1.0894 26.125
NCI-H1755 GDSC2; CTRP2; CTRP1 1.1796 7.3877 0.0214 29.7053
NCI-H2461 GDSC2 1.2815 8.8909 -3.4279 16.9251
NCI-H1568 GDSC2; CTRP2 1.3035 5.9057 0.6979 27.021
NCI-H2818 GDSC2 1.3216 6.4641 -2.2079 10.3844
COR-L95 GDSC1; GDSC2; CTRP2 1.3762 8.028 -0.0379 29.2233
KNS-62 GDSC2; CTRP2 1.4 11.8397 -1.7211 33.5839
NCI-H2023 GDSC2; CTRP2; CTRP1 1.4291 8.6295 -0.2331 29.7209
NCI-H64 GDSC1; GDSC2 1.439 7.9324 -2.8402 13.5866
NCI-H1688 GDSC2 1.4481 14.5168 -6.0897 26.3727
NCI-H1869 GDSC1; CTRP2 1.4489 8.2002 -0.0346 28.9936
NCI-H196 GDSC2; CTRP2 1.4696 6.7668 0.5671 26.9625
NCI-H2591 GDSC2 1.491 6.2304 -1.9773 8.6837
PaCa-3 GDSC2 1.5157 8.9381 -3.2774 15.6237
HCC2935 CTRP2; CTRP1 1.5932 3.5941 1.5535 23.2002
NCI-H1781 GDSC2; CTRP1 1.6773 12.6448 -1.8218 33.0759
NCI-H3255 GDSC2; CTRP1 1.751 3.8066 1.698 20.8113
NCI-H1395 CTRP2 1.7604 8.5398 0.1415 27.5158
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 1.7701 8.8455 0.0232 27.9286
NCI-H2126 CTRP2 1.7733 3.5984 1.7415 21.8994
LC-1/sq-SF CTRP2 1.9154 14.698 -2.5864 33.9451
NCI-H2722 GDSC2 1.9404 3.479 -0.5069 0.4266
HCC4006 CTRP2; CTRP1 1.9428 6.8224 1.0548 23.9193
NCI-H727 GDSC2; CTRP2 1.9642 5.8249 1.4414 22.3782
NCI-H441 GDSC2; CTRP2; CTRP1 1.9682 5.2267 1.6387 21.7249
NCI-H1623 GDSC2; CTRP2 2.0361 9.0865 0.1802 26.6039
NCI-H835 GDSC2 2.2163 4.0089 -0.592 0.5239
NCI-H2342 GDSC2; CTRP2; CTRP1 2.2503 4.9575 2.0208 19.4919
NCI-H1563 GDSC2; CTRP2 2.2521 5.1995 1.9534 19.6518
NCI-H2066 GDSC2 2.3507 4.0277 -0.5464 0.3441
NCI-H2347 GDSC2 2.3678 6.5677 -1.5835 4.8503
HCC1359 CTRP1 2.6284 4.9066 2.4464 35.8982
HCC1171 CTRP2 2.6705 7.2422 1.6424 19.6269
SW1573 GDSC2; CTRP2 2.739 16.7173 -2.8094 32.3546
COLO 699 CTRP2; CTRP1 2.8894 10.6104 0.3181 23.9328
NCI-H1838 GDSC1; GDSC2; CTRP2 3.0583 9.8491 0.8369 21.6309
NCI-H2595 GDSC2 3.0897 5.1846 -0.6793 0.3673
NCI-H292 GDSC2; CTRP2 3.0898 10.6564 0.4798 21.5093
NCI-H2141 GDSC1; GDSC2; CTRP2; CTRP1 3.1981 20.13 -4.0785 33.5758
RERF-LC-Ad1 CTRP2 3.2751 4.4881 3.232 11.9336
NCI-H2444 GDSC2; CTRP2 3.3185 4.0933 3.3133 10.7969
NCI-H226 GDSC1; GDSC2; CTRP2 3.3998 7.5131 2.2677 15.2796
IA-LM GDSC1; GDSC2; CTRP2 3.5857 11.249 0.656 20.9967
NCI-H2196 GDSC1; GDSC2; CTRP2 3.7098 4.7707 3.6524 8.521
NCI-H2085 GDSC2; CTRP2 3.7243 11.7473 0.5379 21.0888
RERF-LC-Ad2 CTRP2 4.1215 7.435 3.0138 10.5003
HCC1195 CTRP2; CTRP1 4.6534 46.3893 -15.9452 40.8687
Lu-165 GDSC1; GDSC2 4.7106 17.753 -5.3244 17.3977
NCI-H2110 GDSC2; CTRP2; CTRP1 4.9509 36.0882 -10.5458 36.7328
Calu-1 CTRP2 5.7725 17.4944 -0.5847 20.4798
Hs 888.Lu CTRP2 1.9406 11.7314 -1.1405 30.697
⏷ Show the Full List of 227 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 0.2365 7.7232 -3.6663 20.8624
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 -7.1508 -6.6396 -7.1508 81.2465
SYO-1 CTRP2 -6.2913 0.0132 -6.3996 71.1974
P-STS CTRP2 -1.8976 5.3968 -2.6307 46.9596
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -3.955 4.5012 -4.634 57.4345
Yamato-SS CTRP2 -1.3433 6.365 -2.3274 44.1428
MES-SA GDSC2; CTRP2 -14.7376 1.3023 -15.6498 82.7654
TE 617.T CTRP2 -6.3834 12.7662 -10.1408 60.4576
KYM-1 GDSC2; CTRP2 -6.0376 -1.7186 -6.0516 72.2119
RD GDSC2; CTRP2 -5.6695 1.8152 -5.9509 66.6736
G-402 GDSC2; CTRP2 -5.6451 -0.9431 -5.6738 69.5335
SW982 GDSC1; GDSC2; CTRP2 -4.8646 -2.0702 -4.8657 65.8666
G-401 GDSC2; CTRP2 -4.7611 1.6829 -4.9612 62.9436
VA-ES-BJ GDSC1; GDSC2 -4.4823 -3.7081 -4.4823 44.9767
TTC-709 CTRP2 -3.9249 4.3942 -4.5745 57.3535
Rh41 GDSC2; CTRP2 -3.8347 2.9851 -4.171 57.6182
SK-UT-1 GDSC1; GDSC2; CTRP2 -3.6022 1.674 -3.7299 56.9436
STS-0421 GDSC2 -3.5574 0.6048 -4.3486 29.6682
GCT GDSC2; CTRP2 -3.4329 4.9866 -4.1914 54.8644
Hs 633.T GDSC2 -3.3756 0.0543 -3.6989 35.3522
HT-1080 GDSC2; CTRP2; CTRP1 -3.3231 5.5345 -4.2228 54.2259
EW-8 GDSC1; GDSC2 -3.1318 -0.811 -3.2355 31.9424
BT-16 CTRP2 -2.8852 6.3752 -4.0063 52.0116
Rh30 GDSC2 -2.3414 1.5859 -3.1128 27.5309
A-204 GDSC2; CTRP2 -2.1619 2.8438 -2.3469 48.1521
SW872 GDSC1; GDSC2 -1.9805 0.2256 -2.227 21.1817
RKN GDSC2; CTRP2; CTRP1 -1.6498 5.1828 -2.2967 45.5356
Rh18 CTRP2 -0.9984 5.9722 -1.8252 41.9751
Tm87-16 CTRP2 -0.9801 8.7845 -2.8279 43.2453
MFH-ino GDSC1; GDSC2 -0.0785 9.8867 -5.0089 27.0667
SW684 GDSC1; GDSC2 1.2482 7.7021 -2.8668 14.1871
TE 441.T GDSC1; GDSC2; CTRP2 1.8835 8.655 0.2173 25.3474
BT-12 CTRP2 2.2178 3.3108 2.2145 18.8423
SK-LMS-1 GDSC1; GDSC2; CTRP2 2.5646 16.7363 -2.9781 33.0792
Hs 729.T CTRP2 8.1209 24.6261 -2.3157 21.1688
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -3.6828 2.7202 -3.9608 56.9631
OVCAR-8 GDSC2; CTRP2; CTRP1 -14.6307 -2.6636 -14.9162 88.133
A2780 GDSC2; CTRP2; CTRP1 -10.3445 3.976 -11.4684 75.0752
OC 314 GDSC2; CTRP2 -7.3575 -6.2764 -7.3575 82.6067
COV434 CTRP2; CTRP1 -5.8475 1.5947 -6.1079 67.62
TOV-112D GDSC2; CTRP2 -5.489 -3.6029 -5.489 70.1441
MCAS CTRP2 -4.6456 39.3526 -20.7298 52.6937
IGROV-1 GDSC2; CTRP2; CTRP1 -4.0736 4.2911 -4.709 58.099
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 -3.6643 1.9271 -3.8243 57.2328
OVK18 GDSC2; CTRP2; CTRP1 -3.5657 -0.1728 -3.5772 53.7796
OV7 CTRP2; CTRP1 -3.1033 11.4111 -6.1305 52.2234
OVCAR-5 GDSC2; CTRP2 -2.6877 4.1621 -3.1704 51.2623
OVCAR-3 GDSC2 -2.5919 1.6025 -3.3842 29.9968
Caov-3 GDSC2; CTRP2; CTRP1 -2.5698 4.2897 -3.0698 47.9501
ES-2 GDSC1; GDSC2 -2.4262 0.3895 -2.7635 26.1127
JHOS-4 GDSC2; CTRP1 -2.3087 5.6366 -3.1464 46.7726
TOV-21G GDSC2; CTRP2 -1.9265 7.1827 -3.2383 47.4436
FU-OV-1 GDSC2; CTRP2 -1.7865 9.7707 -4.0774 47.2499
SK-OV-3 GDSC2; CTRP2 -1.6233 3.4224 -1.8622 44.8385
ONCO-DG-1 CTRP2 -1.3216 4.5254 -1.7684 43.2866
COV644 CTRP2; CTRP1 -1.2844 7.3165 -2.5892 44.2294
OAW42 CTRP2; CTRP1 -1.2346 4.9429 -1.7781 42.9634
TYK-nu GDSC2; CTRP2; CTRP1 -0.7397 5.5624 -1.4136 40.2175
OVKATE GDSC2; CTRP1 -0.7098 2.5603 -0.7703 38.5805
DOV13 GDSC2; CTRP2 -0.5095 7.6545 -1.8865 40.1404
HEY A8 CTRP2 -0.3394 5.85 -1.0694 37.8508
COV362 CTRP2; CTRP1 -0.1827 11.4992 -3.1466 40.8914
RMUG-S CTRP1 -0.1708 5.5863 -0.8007 64.0822
EFO-27 GDSC2; CTRP2; CTRP1 -0.0987 10.7512 -2.7298 38.2411
OAW28 GDSC2; CTRP2 0.0718 8.0677 -1.428 37.145
JHOM-1 CTRP2; CTRP1 0.1834 108.2122 -50.635 48.6621
OV-90 GDSC2; CTRP2; CTRP1 0.4164 4.3093 0.1756 31.6941
SNU-8 CTRP2 0.7495 7.6663 -0.5502 32.7004
OVTOKO GDSC2; CTRP2 1.0454 7.0779 -0.005 30.1452
Kuramochi GDSC1; GDSC2; CTRP2 1.1639 6.5381 0.3248 28.7147
RMG-I GDSC2; CTRP2; CTRP1 1.2934 6.0862 0.6293 27.3566
OVSAHO CTRP2 1.3349 7.9601 -0.0529 29.3953
JHOC-5 CTRP2; CTRP1 1.4952 6.6904 0.628 26.7448
ES2 CTRP2 1.6672 7.5904 0.4488 26.7746
Caov-4 GDSC2 1.7953 6.6174 -1.9587 7.9467
SNU-840 CTRP2; CTRP1 1.8 6.442 1.0478 24.3618
SNU-119 CTRP2 2.0392 4.5637 1.8823 20.5614
EFO-21 GDSC2; CTRP2 2.54 13.5444 -1.4383 29.8621
OVISE GDSC2; CTRP2 2.8346 7.5373 1.6835 19.03
OV56 GDSC2; CTRP2 3.1051 7.5016 1.9753 17.1882
JHOS-2 GDSC2; CTRP2 3.5861 9.7274 1.3989 17.1479
COV318 CTRP1 3.7319 7.3492 2.6811 26.9015
OVMANA CTRP1 3.8267 4.7799 3.7788 17.9534
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 2.7083 6.0532 2.1626 17.5406
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC2; CTRP2 -6.4266 -4.7603 -6.4266 76.374
MPP 89 GDSC1; GDSC2; CTRP2 -3.11 8.0394 -4.8209 52.7181
NCI-H2452 GDSC2; CTRP2 -2.6587 6.6438 -3.8476 50.9358
NCI-H2052 GDSC2; CTRP2 -2.0943 3.9735 -2.4821 47.8619
IST-Mes1 GDSC1; GDSC2; CTRP2 -1.5015 2.8975 -1.6482 43.9141
MSTO-211H GDSC1; GDSC2; CTRP2 0.5998 5.771 -0.0224 31.6447
ACC-MESO-1 CTRP2 2.1127 6.0286 1.5309 21.6135
JL-1 CTRP2 12.0859 38.4907 -6.2359 23.5701
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; GDSC2; CTRP2 -3.6358 2.993 -3.9576 56.6036
LNCaP clone FGC GDSC1; GDSC2; CTRP2 -2.6289 3.601 -2.9843 50.9721
DU145 GDSC2; CTRP2 -1.6557 14.1904 -5.8541 47.4389
22Rv1 GDSC2; CTRP2 -0.5165 10.043 -2.8609 41.6053
NCI-H660 GDSC2 0.6699 2.3053 -1.5544 0.7531
PaCa-3 CTRP2; CTRP1 0.7335 11.2179 -2.0921 36.3579
PC-3 GDSC2 1.8042 6.244 -1.7769 6.8995
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -5.9625 -0.8347 -6.0039 70.8962
A-253 GDSC1; GDSC2 0.6861 4.9403 -1.9242 10.2482
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -4.6826 -3.3823 -4.6849 36.9668
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH-10-TC CTRP2 -8.5026 1.4104 -8.9297 75.3552
GSS CTRP2 -6.3604 -5.4837 -6.3604 75.9803
SNU-16 GDSC1; GDSC2; CTRP2 -6.0379 -0.9358 -6.0768 71.3461
MKN74 CTRP2; CTRP1 -5.8532 15.5289 -10.7365 58.2522
TMK-1 GDSC2 -5.1974 -2.7514 -5.2476 42.3133
23132/87 GDSC2; CTRP2 -5.1473 -2.1296 -5.1489 67.6339
SNU-620 CTRP2 -4.8923 -1.5588 -4.8966 65.8633
NCI-N87 CTRP2 -4.8203 3.9963 -5.4542 61.3703
NCC-StC-K140 CTRP2 -4.4605 5.5773 -5.4788 58.9264
SNU-216 CTRP2 -4.3202 3.2314 -4.7436 59.7926
NUGC-3 GDSC2; CTRP2 -4.1022 1.5891 -4.2496 59.7271
HSC-39 GDSC1; GDSC2 -3.9117 -2.6191 -3.9132 39.2585
HGC-27 GDSC2; CTRP2 -3.7752 0.7633 -3.8322 58.2781
RF-48 GDSC1; GDSC2 -3.6336 -2.4824 -3.6346 36.4661
TGBC11TKB GDSC2 -3.6309 5.26 -6.0437 42.6139
SNU-5 GDSC1; GDSC2; CTRP2 -3.6007 -0.2448 -3.6113 57.4736
MKN1 GDSC2; CTRP2 -2.521 2.2972 -2.6559 50.3761
HuG1-N CTRP2 -2.3724 15.1083 -6.9926 49.7416
AGS GDSC2; CTRP2; CTRP1 -2.164 1.7419 -2.2241 48.1292
GSU CTRP2 -2.0746 4.2489 -2.5229 47.7815
Fu97 GDSC2; CTRP2 -1.9286 3.4729 -2.2012 46.777
Hs 746.T GDSC2; CTRP2 -1.864 9.1889 -3.9255 47.4866
NUGC-4 GDSC2; CTRP2 -1.6457 3.3035 -1.8657 44.9521
IM95 GDSC2; CTRP2 -1.5663 4.3311 -1.9886 44.7379
SNU-719 CTRP2 -1.3707 5.4523 -2.0722 43.9467
SNU-1 GDSC1; GDSC2; CTRP2 -1.2462 2.6724 -1.3481 42.164
GCIY GDSC1; GDSC2 -0.7023 4.3257 -2.7729 19.312
SK-GT-2 GDSC2 -0.3811 6.0115 -3.329 21.1485
KE-39 CTRP2 -0.1358 9.5221 -2.244 39.3951
SCH GDSC1; GDSC2 -0.106 4.3768 -2.9846 10.0933
SNU-601 CTRP2 -0.0544 4.7062 -0.4315 35.1314
RERF-GC-1B GDSC2 -0.0164 7.1048 -3.5661 21.1496
ECC10 GDSC2; CTRP2 0.4267 10.6592 -2.1581 37.3897
MKN28 GDSC2 0.5018 11.3813 -5.2781 26.3223
KATO III GDSC2; CTRP2 1.7425 9.5015 -0.3038 28.9489
SNU-668 CTRP2 2.026 7.2567 0.963 23.9393
OCUM-1 GDSC2 2.6264 4.6546 -0.6663 0.5233
LMSU CTRP2 3.3002 12.6464 -0.2928 24.8181
MKN45 GDSC2; CTRP2 4.1607 5.8474 3.7844 7.2929
ECC12 GDSC2; CTRP2 4.718 16.7556 -1.0854 22.8539
MKN7 GDSC2; CTRP2 7.8049 22.545 -1.5254 18.8259
SNG-M GDSC2; CTRP2; CTRP1 -14.0657 7.3914 -16.493 75.7484
SNU-685 CTRP2 -7.0588 9.1202 -9.4651 64.0318
SNU-1077 CTRP2 -1.5833 3.1624 -1.7753 44.5145
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-238 CTRP2 -13.4445 18.896 -20.0791 67.5056
IHH-4 GDSC2 -6.812 9.5578 -11.1976 55.8935
KMH-2 GDSC2 -5.3363 -3.5481 -5.3441 43.5461
B-CPAP GDSC2; CTRP2 -4.2582 -1.0549 -4.2631 61.7999
SW579 CTRP2 -4.2247 21.3987 -11.7302 53.65
CAL-62 GDSC2; CTRP2 -2.9623 6.703 -4.1969 52.3135
ML-1 [Human leukemia] GDSC2; CTRP2 -2.8303 5.9867 -3.8242 49.3826
8305C GDSC2; CTRP2 -1.0516 4.1791 -1.3937 41.4222
BHT-101 GDSC2; CTRP2 -1.0327 2.883 -1.1467 40.7934
TT2609-C02 GDSC2; CTRP2 -0.8697 5.6905 -1.5971 41.0474
K5 GDSC1; GDSC2 -0.7015 4.5195 -2.8681 19.8272
ASH-3 GDSC2 -0.454 5.128 -2.9515 19.4543
TT GDSC2; CTRP2 0.6696 5.9387 -0.001 31.3465
8505C GDSC2; CTRP2 0.799 6.2845 0.0218 30.8514
FTC-133 GDSC2; CTRP2 1.4496 10.9288 -1.2491 32.3523
WRO GDSC2 1.8583 6.8366 -2.0213 8.1736
HTC-C3 GDSC2 2.2193 4.7001 -0.8591 1.4852
CGTH-W-1 GDSC1; GDSC2; CTRP2 3.5669 4.8181 3.4877 10.1162
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PE/CA-PJ49 CTRP2 -13.0153 11.2108 -16.6363 71.5902
PE/CA-PJ34 (clone C12) CTRP2 -7.3804 18.8754 -13.7707 59.8412
YD-10B CTRP2 -6.2924 -5.1338 -6.2924 75.5244
PCI-15A GDSC2 -5.868 -3.9714 -5.8741 48.858
Ca9-22 GDSC2 -5.2515 -3.4182 -5.2546 52.6853
PCI-06A GDSC2 -5.0401 -3.3271 -5.0488 40.5823
CAL-27 GDSC2; CTRP2 -4.8838 8.8661 -7.0307 58.5893
KON GDSC2 -4.6365 3.3774 -6.6524 42.0422
BB30-HNC GDSC1; GDSC2 -4.4599 -2.9403 -4.4692 34.7669
KOSC-2 GDSC2 -4.2034 -1.6803 -4.3365 32.8021
JHU-011 GDSC2 -3.7827 5.3325 -6.7049 38.3307
Detroit 562 GDSC2; CTRP2 -3.6486 1.349 -3.746 57.3275
JHU-029 GDSC2 -3.4611 1.7467 -4.73 30.9238
PCI-04B GDSC2 -3.3719 1.9471 -4.7277 30.5126
LB771-HNC GDSC1; GDSC2 -3.1924 2.3403 -4.3168 36.6397
OSC-19 GDSC2 -2.9671 3.7549 -5.1654 30.5407
SNU-1214 CTRP2 -2.8346 6.1044 -3.8654 51.8105
HSC-2 GDSC2; CTRP2 -2.5654 167.8861 -82.8018 50.0337
SAT [Human HNSCC] GDSC2 -2.2217 1.4914 -2.9482 26.1562
SAS GDSC2 -2.1427 2.9959 -3.5174 28.5856
SKN-3 GDSC2 -2.03 3.702 -3.7298 29.044
BICR 18 CTRP2 -1.8319 4.5346 -2.327 46.3989
SCC-25 GDSC2; CTRP2 -1.3833 7.34 -2.7083 42.5054
SCC-9 GDSC2; CTRP2; CTRP1 -1.1312 6.4834 -2.133 43.0381
SNU-1076 CTRP2 -0.9746 6.8344 -2.0875 42.2806
SNU-46 CTRP2 -0.9738 8.9928 -2.9048 43.3063
CAL-33 GDSC2; CTRP2 -0.848 6.4885 -1.8314 41.3677
PE/CA-PJ15 GDSC2; CTRP2 -0.5505 8.9189 -2.4283 39.1451
PCI-30 GDSC2 -0.5352 3.1791 -2.055 14.5915
BICR 22 GDSC2; CTRP2 -0.4661 6.0451 -1.2696 38.7847
OSC-20 GDSC2 -0.4613 5.9027 -3.344 21.4808
BICR 6 CTRP2 -0.3855 778.3748 -386.155 49.8536
DOK GDSC2 -0.2683 7.7876 -4.1196 24.3489
SNU-1066 CTRP2 -0.1875 4.9405 -0.6373 36.1921
HSC-3 GDSC2; CTRP2 -0.1805 6.6463 -1.1635 37.4725
BICR 31 GDSC2; CTRP2 0.1611 7.0482 -0.9405 33.6891
HO-1-N-1 GDSC2 0.3175 18.8937 -9.1836 35.2088
BICR 16 CTRP2 0.3698 11.4084 -2.5516 38.2442
HSC-4 GDSC2; CTRP2 0.4741 9.109 -1.4342 35.7925
BHY GDSC2; CTRP2 0.4807 6.4698 -0.3871 31.1778
NCI-H3118 GDSC2 0.522 9.1535 -4.1493 22.152
JHU-022 GDSC2 0.712 12.2058 -5.5201 26.5245
UPCI-SCC-090 GDSC2 0.7154 7.8765 -3.3591 18.0654
BB49-HNC GDSC1 0.802 3.7725 -2.9874 2.0457
HO-1-u-1 GDSC2 0.9817 3.9327 -1.2206 5.2932
SCC-15 GDSC1; GDSC2 1.0714 7.1045 -2.7037 13.753
BICR 78 GDSC2 1.3893 8.9824 -3.3925 16.4887
SNU-1041 CTRP2 1.4656 10.9356 -1.2363 32.2749
SCC-4 GDSC2 1.5618 45.4412 -21.4326 41.9208
SNU-899 CTRP2 1.8129 4.367 1.6769 21.9948
YD-8 CTRP2 1.8521 10.205 -0.5146 29.2523
FaDu GDSC2; CTRP2 2.1673 12.0941 -1.0933 29.9623
BICR 56 CTRP2 2.8872 5.8292 2.4373 15.9947
PE/CA-PJ41 (clone D2) CTRP2 2.8972 9.9126 0.6509 22.7019
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCaBER CTRP2 -14.7902 3.0406 -16.0892 80.7421
RT-112 GDSC2; CTRP2 -9.7545 6.924 -11.6559 70.9679
JMSU-1 CTRP2 -6.5977 2.5991 -7.0866 68.9294
BFTC-905 GDSC2; CTRP2 -5.0641 5.9593 -6.2501 60.8492
5637 GDSC2; CTRP2 -4.9405 -0.4147 -4.9726 65.4809
SW1710 GDSC2; CTRP2 -4.7537 65.5518 -33.7182 51.7826
BC-3C CTRP2 -4.6606 18.5013 -10.8363 54.9916
253J CTRP2 -3.7131 -0.5054 -3.7204 58.2347
639V GDSC2; CTRP2 -3.3444 4.2964 -3.9176 54.6584
647V GDSC2; CTRP2 -3.3422 1.0848 -3.404 55.5879
UM-UC-1 CTRP2 -3.2006 58.7186 -28.9396 50.6525
CAL-29 GDSC2; CTRP2 -2.9967 5.664 -3.9078 52.643
VM-CUB-1 CTRP2 -2.2417 2.3232 -2.3627 48.618
SW780 GDSC2 -2.1486 1.5972 -2.9144 25.6581
253J-BV CTRP2 -1.8045 5.4194 -2.5357 46.4418
UM-UC-3 GDSC2; CTRP2 -1.7418 10.4728 -4.3198 47.185
U-BLC1 CTRP2 -1.154 5.4856 -1.8455 42.6679
TCCSUP GDSC2; CTRP2 1.5154 9.4938 -0.5306 30.2702
J82 GDSC2; CTRP2 1.8208 8.8668 0.0596 27.6039
HT-1376 GDSC2; CTRP2 2.1615 4.6525 1.9959 19.7782
HT-1197 GDSC2; CTRP2 2.2772 4.9067 2.0609 19.1881
RT-4 GDSC2; CTRP2 2.6817 14.9128 -1.9747 30.7658
KU-19-19 GDSC2; CTRP2 2.8606 5.7732 2.4288 16.1033
KMBC-2 CTRP2 2.895 5.3881 2.5966 15.3787
T24 GDSC2; CTRP2 5.8899 18.4941 -0.9894 20.4438
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PWR-1E GDSC2 -5.9146 -3.0816 -5.9405 58.9368
C-33 A GDSC2 -5.5562 -2.6002 -5.5988 55.4726
TC-YIK GDSC2 -5.4999 1.215 -6.3731 53.4871
SW954 GDSC1; GDSC2 -5.3442 -4.4264 -5.3442 43.5948
JEG-3 GDSC2 -4.8318 -0.3077 -5.3895 40.4147
NT2-D1 GDSC1; GDSC2 -4.4867 -3.5418 -4.4867 45.0212
JAR GDSC1; GDSC2 -4.475 -2.0868 -4.5604 35.2812
NCC-IT GDSC1; GDSC2 -4.1335 0.3859 -4.622 42.8959
PA-1 GDSC2 -4.1325 -1.9841 -4.1606 41.587
ACC-OV7 GDSC2 -3.3147 1.3305 -4.3978 28.7899
MS751 GDSC2 -3.1462 0.2843 -3.5152 33.3358
SW962 GDSC1; GDSC2 -3.1284 4.5527 -5.702 33.0536
UWB1.289 GDSC2 -2.9735 1.5869 -4.1619 26.1706
LB831-BLC GDSC1; GDSC2 -2.5825 1.8429 -3.4714 30.351
HeLa GDSC2; CTRP2 -2.5156 3.837 -2.9105 50.315
Ca Ski GDSC2 -2.22 9.5416 -6.7272 38.168
NEC8 GDSC1; GDSC2 -2.186 2.0428 -3.1408 26.9773
SiSo GDSC2 -1.9201 1.5029 -2.6358 23.1794
CAL-39 GDSC2 -1.7806 8.1148 -5.6225 34.334
BPH-1 GDSC2 -1.665 6.3582 -4.6547 31.1053
KGN GDSC1; GDSC2 -1.1881 5.5446 -3.8155 26.1427
PEO1 GDSC2 -1.0822 8.2769 -5.0717 30.396
ME-180 GDSC2 -0.8891 5.1859 -3.3666 23.0275
OV17R GDSC2 -0.5526 4.0408 -3.158 12.2731
HEY GDSC2 -0.494 3.7019 -2.2772 15.7874
SKN GDSC2 -0.386 5.7408 -3.1981 20.5123
OVCA433 GDSC2 -0.2077 5.2025 -3.4683 13.1595
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 0.1431 6.2412 -3.7177 13.6512
SKG-IIIa GDSC2 0.5185 8.0232 -3.5881 19.6986
C-4-I GDSC2 0.5373 6.3225 -2.7254 15.2711
HT-3 GDSC2 0.5392 5.0028 -2.0674 11.4882
SiHa GDSC2 0.5868 3.6433 -1.3588 7.0333
OVCA420 GDSC2 0.611 4.3145 -1.6716 8.9031
OVMIU GDSC2 0.6971 5.7493 -2.3163 12.5376
JHOS-3 GDSC2 1.0233 3.7265 -1.9661 2.1788
HEC-1 GDSC2 1.1709 6.3484 -2.2592 11.0293
SW756 GDSC2 1.2734 2.8076 -0.5382 1.0484
DSH1 GDSC1; GDSC2 1.4457 7.8057 -2.7735 13.2177
DoTc2 4510 GDSC2 2.2344 4.059 -0.6033 0.5468
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5666).
2 Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. Oncologist. 2009 Jun;14(6):559-70.
3 BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1. Cancer Med. 2013 Dec;2(6):826-35. doi: 10.1002/cam4.146. Epub 2013 Oct 31.