Details of the Drug

General Information of Drug (ID: DMJT8Q0)

Drug Name
Dezinamide
Synonyms ADD-94057; ADDR-84116; AHR-11748; AN-051
Indication
Disease Entry ICD 11 Status REF
Epileptic seizures 8A61-8A6Z Discontinued in Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 260.209
Logarithm of the Partition Coefficient (xlogp) 1.5
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C11H11F3N2O2
IUPAC Name
3-[3-(trifluoromethyl)phenoxy]azetidine-1-carboxamide
Canonical SMILES
C1C(CN1C(=O)N)OC2=CC=CC(=C2)C(F)(F)F
InChI
InChI=1S/C11H11F3N2O2/c12-11(13,14)7-2-1-3-8(4-7)18-9-5-16(6-9)10(15)17/h1-4,9H,5-6H2,(H2,15,17)
InChIKey
LIAILJLSVRAGSM-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
146291
CAS Number
91077-32-6
TTD ID
D01BBR
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Gamma-aminobutyric acid receptor (GAR) TTNJYV2 NOUNIPROTAC Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000082)
2 Clobazam, oxcarbazepine, tiagabine, topiramate, and other new antiepileptic drugs. Epilepsia. 1995;36 Suppl 2:S105-14.