Details of the Drug

General Information of Drug (ID: DMJX3O8)

Drug Name
OSI-027
Indication
Disease Entry ICD 11 Status REF
Renal cell carcinoma 2C90 Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 406.4
Logarithm of the Partition Coefficient (xlogp) 2
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C21H22N6O3
IUPAC Name
4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic acid
Canonical SMILES
COC1=CC=CC2=C1NC(=C2)C3=C4C(=NC=NN4C(=N3)C5CCC(CC5)C(=O)O)N
InChI
InChI=1S/C21H22N6O3/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29/h2-4,9-12,25H,5-8H2,1H3,(H,28,29)(H2,22,23,24)
InChIKey
JROFGZPOBKIAEW-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
135398516
ChEBI ID
CHEBI:91363
CAS Number
936890-98-1
UNII
25MKH1SZ0M
DrugBank ID
DB12387
TTD ID
D0H7XL
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serine/threonine-protein kinase mTOR (mTOR) TTCJG29 MTOR_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Renal cell carcinoma
ICD Disease Classification 2C90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Serine/threonine-protein kinase mTOR (mTOR) DTT MTOR 2.16E-05 -0.44 -2.3
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 -1.5535 2.8967 -1.7647 48.0192
ES5 GDSC1; GDSC2 -2.542 2.6058 -2.7798 60.2882
ES8 GDSC1; GDSC2 -2.4705 1.4472 -2.5478 54.9489
EW-7 GDSC1; GDSC2 -2.1065 0.8664 -2.1297 52.2702
ES1 GDSC1; GDSC2 -2.0337 1.8142 -2.1243 51.6261
EW-11 GDSC1; GDSC2 -1.9179 2.9918 -2.1762 50.6898
SK-PN-DW GDSC1; GDSC2 -1.7707 1.8404 -1.8495 49.6057
ES7 GDSC1; GDSC2 -1.7315 2.5269 -1.895 49.3261
EW-18 GDSC1; GDSC2 -0.1637 5.1193 -0.8122 38.5753
TC-71 GDSC1; GDSC2 0.1768 5.0728 -0.427 35.8954
EW-3 GDSC1; GDSC2 0.2152 7.7565 -1.4075 38.3355
SK-N-MC CTRP2 0.2381 4.1099 0.1121 39.0467
EW-1 GDSC1; GDSC2 0.9378 4.5264 0.5709 29.0623
MHH-ES-1 GDSC1; GDSC2; CTRP2 1.2186 4.6604 1.0809 32.6032
SK-ES-1 GDSC1; GDSC2; CTRP2 1.4399 6.7355 0.815 32.6793
NOS-1 [Human HNSCC] GDSC1; GDSC2 1.535 9.9129 -1.0366 32.4106
HuO9 GDSC1; GDSC2 1.5909 10.1811 -1.1085 32.4232
A-673 GDSC1; GDSC2; CTRP2 1.7176 5.0808 1.5464 29.4025
ES6 GDSC1; GDSC2 1.7252 9.9887 -0.8867 31.329
SJSA-1 GDSC1; GDSC2; CTRP2 2.06 10.2155 0.1264 32.5787
CADO-ES1 GDSC1; GDSC2 2.1667 5.771 1.461 20.6915
EW-16 GDSC1; GDSC2 2.5552 9.5825 0.1053 25.2601
TC71 CTRP2 2.6035 5.9534 2.3137 23.9299
EW-12 GDSC2 3.068 7.4548 1.0402 15.0479
EW-13 GDSC1; GDSC2 3.1003 6.5927 2.0574 14.8578
Hs 888.T CTRP2 3.1548 7.8121 2.2789 22.4214
H-EMC-SS GDSC1; GDSC2 3.1853 12.5498 -0.7738 26.5295
ES4 GDSC1; GDSC2 3.3071 8.8594 1.1604 18.5609
SW1353 CTRP2 3.4764 8.3507 2.3946 21.093
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 3.4887 11.8248 0.8218 26.5091
U-CH2 GDSC2 3.9764 9.1124 0.9524 12.9564
EW-22 GDSC2 3.9828 6.2534 1.2105 1.4203
U2OS GDSC1; GDSC2; CTRP2 4.0223 8.7288 2.7894 18.1283
MG-63 GDSC1; GDSC2; CTRP2 4.6261 11.2247 2.1945 18.93
CAL-78 GDSC1; GDSC2; CTRP2 4.9579 11.8573 2.1893 18.1841
HuO-3N1 GDSC1; GDSC2 4.9911 18.2139 -2.0746 25.92
CHSA0011 GDSC1; GDSC2 5.5572 16.5891 -0.815 22.5879
SaOS-2 GDSC1; GDSC2; CTRP2 5.7256 12.2075 2.6933 14.579
HOS GDSC1; GDSC2; CTRP2 5.7535 10.1172 3.7608 10.1674
EW-24 GDSC1; GDSC2 6.1382 7.2572 3.9618 0.1155
CAL-72 GDSC1; GDSC2 6.4711 7.8677 3.8706 0.173
CHSA0108 GDSC1; GDSC2 6.693 20.3903 -1.832 23.2891
Hs 822.T CTRP2 7.6586 16.9831 1.8551 14.1713
CHSA8926 GDSC1; GDSC2 7.8405 20.4032 -1.0087 17.2616
NY GDSC1; GDSC2 9.5112 26.8094 -2.9461 20.1068
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 219 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 0.4262 5.3781 0.0813 38.3911
MEC1 CTRP2 0.878 5.7815 0.4757 35.6403
JM1 GDSC1; GDSC2; CTRP2 2.691 8.028 1.7016 25.8372
SU-DHL-16 GDSC1; GDSC2 -4.3048 -3.6901 -4.3048 78.6741
Karpas-231 GDSC1; GDSC2 -4.1697 -3.3375 -4.1697 69.1108
BL-41 GDSC1; GDSC2 -3.9288 -2.386 -3.9289 67.1325
Sc-1 GDSC1 -3.69 3.5556 -4.225 74.9821
EB2 GDSC1; GDSC2 -3.5526 0.3473 -3.5941 63.1036
MY-M12 GDSC1; GDSC2 -3.5105 5.2511 -4.4965 62.5455
HAL-01 GDSC1; GDSC2 -3.2917 -0.1128 -3.3066 61.5693
QIMR-WIL GDSC1; GDSC2 -2.8804 0.9962 -2.9389 64.1512
SU-DHL-5 GDSC1; GDSC2 -2.7993 -1.0202 -2.7995 57.9472
Ramos.2G6.4C10 GDSC1; GDSC2 -2.5384 -0.1655 -2.5421 55.7917
LC4-1 GDSC1; GDSC2 -2.4452 1.9893 -2.5817 54.608
PL-21 GDSC1; GDSC2 -2.3131 3.4168 -2.6936 58.1706
P30/OHK GDSC1; GDSC2 -2.2869 1.0071 -2.323 53.6617
CCRF-CEM GDSC1; GDSC2 -2.1417 -0.409 -2.1421 52.6031
NKM-1 GDSC1; GDSC2 -2.09 1.5473 -2.1574 52.08
JSC-1 GDSC1; GDSC2 -1.8021 5.2676 -2.6417 49.8825
GR-ST GDSC1; GDSC2 -1.7834 3.3808 -2.1096 49.7317
Farage GDSC1; GDSC2 -1.7185 2.8209 -1.9294 54.4121
MHH-PREB-1 GDSC1; GDSC2 -1.6483 3.1994 -1.925 48.7541
P32/ISH GDSC1; GDSC2 -1.6011 2.8588 -1.8094 48.3717
Ri-1 CTRP2 -1.5737 7.3822 -2.6698 50.5465
TUR GDSC1; GDSC2 -1.5401 2.6451 -1.708 47.8853
WIL2 NS GDSC1; GDSC2 -1.5356 2.9936 -1.7631 47.8984
MV4-11 GDSC1; GDSC2; CTRP2 -1.4478 1.7701 -1.4653 49.9151
SUP-B8 GDSC2 -1.3188 1.8877 -1.4354 46.7905
Pfeiffer CTRP2 -1.2635 3.2545 -1.3779 48.7531
KMOE-2 GDSC1; GDSC2 -1.1903 1.5877 -1.2222 44.9445
MLMA GDSC1; GDSC2 -1.1234 4.6166 -1.7037 45.3148
Loucy GDSC1; GDSC2 -1.1054 2.1785 -1.1825 44.3664
MN-60 GDSC1; GDSC2 -1.1045 3.7632 -1.4574 44.8606
NCI-H929 GDSC2; CTRP2 -1.0343 1.7947 -1.0448 47.1761
SUP-T11 CTRP2 -1.0246 4.2277 -1.2609 47.3368
BC-1 GDSC1; GDSC2 -0.8593 2.73 -0.9908 42.544
KMS-26 CTRP2 -0.8427 1.3954 -0.845 45.8881
EoL-1 GDSC1; GDSC2; CTRP2 -0.7276 2.1494 -0.7424 45.1495
VL51 GDSC1; GDSC2 -0.6644 6.3465 -1.7813 43.0134
NU-DUL-1 GDSC1; GDSC2; CTRP2 -0.6054 2.9201 -0.6554 44.4115
SU-DHL-8 GDSC1; GDSC2; CTRP2 -0.5549 5.1579 -0.9363 44.6137
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 -0.5409 5.5425 -1.0117 44.6477
ML-2 GDSC1; GDSC2 -0.5312 1.9963 -0.5646 39.6204
ATN-1 GDSC1; GDSC2 -0.4002 4.4709 -0.8729 39.873
YT GDSC1; GDSC2 -0.3666 3.0808 -0.5172 38.6857
GDM-1 GDSC1; GDSC2; CTRP2 -0.225 6.8335 -1.0283 43.246
ARH-77 GDSC1; GDSC2 -0.2191 6.055 -1.1956 39.777
SU-DHL-6 GDSC1; GDSC2; CTRP2 -0.1918 2.3633 -0.2027 41.5789
KMS-27 CTRP2 -0.1526 2.7169 -0.1751 41.3504
IM-9 GDSC2 -0.1324 3.2361 -0.7517 24.7251
NB4 GDSC1; GDSC2; CTRP2 -0.0429 4.085 -0.1845 40.927
BE-13 GDSC1; GDSC2 -0.0361 5.2785 -0.7259 37.7466
KMS-12-BM GDSC1; GDSC2; CTRP2 0.042 5.9582 -0.4829 41.2009
Daudi GDSC1; GDSC2; CTRP2 0.0525 3.5084 -0.0157 40.1148
L-1236 GDSC1; GDSC2 0.0574 5.2388 -0.6113 36.9922
BL-70 CTRP2 0.0584 2.9987 0.0282 39.9705
BV-173 GDSC1; GDSC2; CTRP2 0.1285 5.2111 -0.2048 40.2635
CRO-AP2 GDSC2 0.1383 4.0157 -0.364 34.2713
SUP-M2 GDSC1; GDSC2; CTRP2 0.1591 2.8516 0.1392 39.2705
KG-1 GDSC1; GDSC2 0.1731 4.1436 -0.1584 35.0151
Ki-JK CTRP2 0.2348 2.7845 0.2194 38.753
OCI-AML-3 GDSC1; GDSC2; CTRP2 0.2537 4.1814 0.1188 38.9679
KHM-1B CTRP2 0.2802 3.8965 0.1839 38.6877
MEG-01 GDSC1; GDSC2 0.2816 4.4819 -0.1321 34.4509
SUP-B15 GDSC1; GDSC2; CTRP2 0.3172 3.1887 0.2849 38.2563
Karpas-1106P GDSC2 0.3431 2.4792 0.0414 18.2559
MOLM-16 GDSC2; CTRP2 0.3505 6.1619 -0.202 39.357
NOMO-1 GDSC1; GDSC2 0.3545 4.2945 -0.0004 33.6648
MM1.S GDSC2; CTRP2 0.3744 4.0618 0.2637 38.1064
RPMI-8226 GDSC1; GDSC2; CTRP2 0.3876 3.9319 0.2937 37.9712
WSU-DLCL2 GDSC1; GDSC2; CTRP2 0.4109 4.9751 0.1518 38.2703
KE-37 GDSC1; GDSC2; CTRP2 0.4176 3.9114 0.3278 37.7608
JURL-MK1 GDSC1; GDSC2; CTRP2 0.4349 3.7347 0.3649 37.5879
MOLM-13 GDSC1; GDSC2; CTRP2 0.4596 3.0198 0.4405 37.2681
NCO2 CTRP2 0.5262 3.3052 0.4943 36.8653
CTB-1 GDSC1; GDSC2 0.5367 4.3631 0.1797 35.9772
KOPN-8 GDSC1; GDSC2 0.5371 3.5572 0.3723 31.4715
OCI-Ly7 GDSC2 0.5548 5.8117 -0.6128 33.1778
A4/Fukuda GDSC1; GDSC2; CTRP2 0.5712 7.44 -0.3606 38.8347
BONNA-12 GDSC2 0.5816 5.8992 -0.6224 33.0869
GA-10 GDSC2; CTRP2 0.5865 4.2394 0.4662 36.7342
A3/Kawakami GDSC1; GDSC2; CTRP2 0.6761 3.2736 0.6511 35.8457
MOLT-4 GDSC1; GDSC2 0.6982 5.0367 0.1512 31.6736
HC-1 GDSC1; GDSC2 0.7035 6.9502 -0.561 34.0911
KMS-28BM CTRP2 0.7184 6.121 0.2108 36.9444
SCC-3 GDSC1; GDSC2 0.7489 3.72 0.5688 29.8196
NK-92MI GDSC2 0.8191 4.5808 0.167 28.4794
AMO1 GDSC1; CTRP2 0.8203 6.4851 0.217 36.5491
Karpas-45 GDSC1; GDSC2 0.8225 7.2072 -0.543 33.562
Karpas-422 GDSC1; GDSC2; CTRP2 0.834 6.8577 0.1169 36.7519
NU-DHL-1 CTRP2 0.8672 4.2336 0.7662 34.8167
EB1 CTRP2 0.8734 7.1938 0.0501 36.7716
THP-1 GDSC1; GDSC2; CTRP2 0.9104 5.7988 0.5066 35.4355
LP-1 GDSC1; GDSC2; CTRP2 0.977 5.2331 0.7127 34.5942
DEL GDSC1; GDSC2; CTRP2 0.9814 5.7067 0.6074 34.8908
MOLP-8 GDSC1; GDSC2; CTRP2 0.9906 3.5356 0.9614 33.7657
KMS-18 CTRP2 0.9984 4.4234 0.8805 33.9998
DoHH2 GDSC2; CTRP2 1.0109 3.7127 0.9705 33.667
KMS-20 CTRP2 1.0618 4.3815 0.9541 33.5468
ROS-50 GDSC1; GDSC2 1.0697 8.9655 -1.0606 37.1693
H9 GDSC1; GDSC2 1.0776 6.4929 0.0195 30.6637
RS4;11 GDSC1; GDSC2; CTRP2 1.0936 6.5521 0.4947 34.812
MOLT-16 GDSC1; GDSC2; CTRP2 1.0947 4.7536 0.9324 33.5031
MOTN-1 CTRP2 1.1376 10.2315 -0.8364 37.7403
Reh GDSC1; GDSC2; CTRP2 1.1775 5.2245 0.9323 33.2183
HT GDSC1; GDSC2; CTRP2 1.1822 5.3161 0.9178 33.2474
RCH-ACV GDSC2; CTRP2 1.253 5.9477 0.8415 33.239
Karpas-299 GDSC1; GDSC2; CTRP2 1.2716 5.9371 0.8646 33.1043
PL21 CTRP2 1.2881 6.9925 0.5669 33.9257
DB GDSC1; GDSC2; CTRP2 1.2924 7.0559 0.5507 33.9566
SU-DHL-4 GDSC1; GDSC2; CTRP2 1.3098 4.9703 1.126 32.1484
EM-2 GDSC1; GDSC2; CTRP2 1.3244 6.6298 0.7223 33.3503
OCI-Ly3 CTRP2 1.3295 5.5142 1.0334 32.379
BC-3 GDSC1; GDSC2 1.335 5.4802 0.686 30.2045
MOLM-6 CTRP2 1.3371 8.1906 0.195 34.7611
Hs 611.T CTRP2 1.3378 5.6401 1.0124 32.4177
Kasumi-1 GDSC1; GDSC2; CTRP2 1.3649 4.9239 1.194 31.7416
JVM-3 GDSC1; GDSC2; CTRP2 1.4281 5.8948 1.0465 32.0038
OCI-AML-2 GDSC1; GDSC2; CTRP2 1.4617 5.0742 1.2707 31.1662
MOLT-13 GDSC1; GDSC2; CTRP2 1.4678 7.4027 0.6225 33.1509
Karpas-620 GDSC1; GDSC2; CTRP2 1.517 6.3645 1.0126 31.8118
OPM-2 GDSC1; GDSC2; CTRP2 1.5449 3.8049 1.5193 30.0617
CA46 GDSC1; GDSC2; CTRP2 1.5836 6.3689 1.0839 31.3645
SIG-M5 GDSC1; GDSC2; CTRP2 1.5859 4.1113 1.5394 29.8588
PF-382 GDSC1; GDSC2; CTRP2 1.6121 6.0847 1.1963 30.9096
KMS-11 GDSC1; GDSC2; CTRP2 1.6266 8.1079 0.5361 32.864
697 GDSC1; GDSC2; CTRP2 1.6637 4.4565 1.5851 29.4487
KCL-22 GDSC1; GDSC2; CTRP2 1.667 4.2714 1.6094 29.3562
RPMI-6666 GDSC1; GDSC2; CTRP2 1.7136 5.5364 1.4465 29.751
MC116 GDSC1; GDSC2; CTRP2 1.7411 3.4983 1.7337 28.6939
MOLT-3 CTRP2 1.7865 5.222 1.5935 29.0186
NALM-6 GDSC1; GDSC2; CTRP2 1.7872 4.6863 1.6864 28.7017
RL GDSC1; GDSC2; CTRP2 1.7976 4.9203 1.6612 28.7533
Mono-Mac-1 CTRP2 1.8043 8.1332 0.7163 31.7615
MOLP-2 CTRP2 1.8154 11.9171 -0.8796 35.6454
SUP-T1 GDSC1; GDSC2; CTRP2 1.8648 7.0422 1.1762 30.1482
JVM-2 GDSC1; GDSC2; CTRP2 1.8716 6.5067 1.3564 29.5381
L-363 GDSC1; GDSC2; CTRP2 1.8719 4.3357 1.8189 27.9762
Ku812 GDSC1; GDSC2; CTRP2 1.8779 5.212 1.6946 28.3788
Mino CTRP2 1.892 7.0501 1.2031 29.9739
Namalwa GDSC1; GDSC2; CTRP2 1.9067 5.1577 1.7363 28.1436
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 1.9706 6.8831 1.3442 29.2612
KE-97 CTRP2 1.9945 5.0152 1.8571 27.4471
L-540 GDSC1; GDSC2; CTRP2 2.0289 4.8585 1.9197 27.1218
KMS-21-BM CTRP2 2.0323 4.7851 1.9343 27.0606
LAMA-84 GDSC1; GDSC2; CTRP2 2.0583 5.2136 1.8897 27.1297
RPMI-8402 GDSC1; GDSC2; CTRP2 2.1039 5.1096 1.9585 26.7466
P12-Ichikawa GDSC1; GDSC2; CTRP2 2.1079 6.0799 1.7386 27.492
SU-DHL-10 GDSC1; GDSC2; CTRP2 2.1084 3.3272 2.1075 26.2252
MHH-CALL-4 GDSC2; CTRP2 2.1107 8.0246 1.0852 29.6562
SET-2 CTRP2 2.1183 6.3016 1.6868 27.6375
CML-T1 GDSC2; CTRP2 2.1297 5.7517 1.8484 27.044
HuNS1 CTRP2 2.149 7.7758 1.2207 29.1019
CTV-1 GDSC1; GDSC2 2.1529 7.1529 0.8522 23.4765
SU-DHL-1 GDSC1; GDSC2; CTRP2 2.1658 5.2604 1.9969 26.4159
HEL GDSC1; GDSC2; CTRP2 2.166 4.7222 2.0858 26.1096
KYO-1 CTRP2 2.1777 6.5469 1.6773 27.4834
Hs 445 GDSC1; GDSC2 2.1986 8.5105 0.2728 25.7376
M-07e CTRP2 2.2302 7.0228 1.5788 27.6565
RPMI-8866 GDSC1; GDSC2 2.2326 5.8678 1.4909 20.3297
HD-MY-Z CTRP2 2.2367 8.7666 0.9239 29.7679
Raji GDSC1; GDSC2; CTRP2 2.3199 7.6818 1.439 27.8522
Kasumi-2 CTRP2 2.3477 6.4141 1.9034 26.1691
Mono-Mac-6 GDSC1; GDSC2; CTRP2 2.3845 11.7674 -0.2399 32.52
DG-75 GDSC1; GDSC2 2.4974 7.6672 0.9613 21.8799
OCI-Ly10 CTRP2 2.5622 7.811 1.6491 26.4021
F-36P CTRP2 2.5754 6.1755 2.222 24.3422
ME1 GDSC1; GDSC2 2.6255 10.693 -0.3683 26.7819
SK-MM-2 GDSC1; GDSC2; CTRP2 2.629 5.6932 2.4068 23.5212
HEL 92.1.7 CTRP2 2.6907 5.7624 2.4574 23.1499
ALL-PO GDSC1; GDSC2 2.7465 6.2066 1.8784 16.8212
U266B1 GDSC1; GDSC2; CTRP2 2.7473 6.7566 2.2292 23.7937
MHH-CALL-2 GDSC2 2.7512 7.0055 0.0924 9.9856
WSU-NHL GDSC1; GDSC2 2.7548 16.2634 -3.0003 33.401
OCI-Ly19 GDSC1; GDSC2; CTRP2 2.7816 5.7862 2.5506 22.5376
U-937 CTRP2 2.8087 5.91 2.549 22.4593
KM-H2 GDSC1; GDSC2; CTRP2 2.81 8.0534 1.8176 25.0809
CESS GDSC1; GDSC2 2.8967 4.3997 2.7446 12.2529
JeKo-1 GDSC2; CTRP2 2.9176 9.167 1.4655 25.9906
SUP-HD1 GDSC1; GDSC2; CTRP2 2.9511 5.8469 2.7203 21.4093
EHEB CTRP2 2.9643 8.1337 1.9484 24.1686
HL-60 GDSC1; GDSC2; CTRP2 2.9804 6.5645 2.5453 21.9512
Peer CTRP2 3.0149 6.5081 2.6009 21.6458
ST486 GDSC1; GDSC2; CTRP2 3.021 7.6425 2.2034 23.0819
OCI-M1 GDSC1; GDSC2; CTRP2 3.0395 4.1086 3.0375 20.0258
VAL GDSC1; GDSC2 3.1722 5.322 2.7017 11.5
JJN-3 GDSC1; GDSC2; CTRP2 3.1886 6.168 2.8932 20.0618
ALL-SIL GDSC1; GDSC2; CTRP2 3.1962 5.4644 3.073 19.3977
L-428 GDSC1; GDSC2; CTRP2 3.1969 5.7954 3.0011 19.6491
K-562 GDSC1; GDSC2; CTRP2 3.2503 7.6499 2.4445 21.5373
Jiyoye GDSC1; GDSC2 3.2768 5.7432 2.6243 11.5414
SEM CTRP2 3.2885 5.8206 3.0949 19.032
SR GDSC1; GDSC2; CTRP2 3.3138 6.3218 2.9843 19.3537
P31/FUJ GDSC1; GDSC2; CTRP2 3.4073 8.6728 2.1848 22.0635
TK [Human B-cell lymphoma] GDSC1; GDSC2 3.4249 5.0061 3.098 8.781
EJM GDSC1; GDSC2; CTRP2 3.4415 6.8738 2.9407 19.1384
Granta-519 GDSC1; GDSC2; CTRP2 3.4574 7.4844 2.7296 19.8844
BALL-1 GDSC1; GDSC2 3.4791 5.1979 3.0729 8.7247
CMK CTRP2 3.5011 6.3308 3.1857 18.058
Jurkat GDSC2; CTRP2 3.5872 6.4384 3.2457 17.5819
U-698-M GDSC1; GDSC2 3.6935 12.4643 -0.2841 23.4713
KY821 GDSC1; GDSC2 3.7778 7.1253 2.4444 11
SKM-1 GDSC2; CTRP2 3.8154 5.4982 3.7363 15.1203
TF-1 CTRP2 4.0826 9.0513 2.7038 18.3054
OCI-AML-5 GDSC1; GDSC2; CTRP2 4.3167 6.4471 4.0354 12.5149
KO52 CTRP2 4.3298 10.1785 2.4187 18.788
AML-193 CTRP2 4.423 7.3997 3.7826 13.1843
HPB-ALL CTRP2 4.766 7.252 4.202 10.6273
RC-K8 GDSC1; GDSC2 4.8006 10.3227 1.7105 12.1959
HDLM-2 GDSC1; GDSC2; CTRP2 4.8952 9.8637 3.109 14.719
Ci-1 CTRP2 4.9699 8.5164 3.8288 11.616
MHH-CALL-3 CTRP2 5.1133 10.995 2.756 15.6387
HuT 78 CTRP2 5.251 8.1607 4.2694 9.1479
ME1 CTRP2 5.4003 11.4901 2.7677 14.9656
DND-41 GDSC1; GDSC2; CTRP2 5.6591 10.2522 3.6114 10.9828
P3HR-1 CTRP2 6.1205 13.9803 2.1397 15.918
KMM-1 CTRP2 7.3962 12.4154 3.903 6.6908
REC-1 CTRP2 8.2376 10.8856 5.1152 1.2058
Toledo CTRP2 8.3868 10.6311 5.2861 0.6544
⏷ Show the Full List of 219 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.8751 10.3722 0.8885 27.9855
TE15 CTRP2 4.3262 8.8648 3.0327 16.3972
TE-5 GDSC1; GDSC2; CTRP2 0.7103 8.2617 -0.5036 38.6037
TE-15 GDSC1; GDSC2 1.7115 8.3314 -0.127 28.8828
OE21 GDSC1; GDSC2; CTRP2 2.1901 6.6919 1.645 27.5553
KYSE-270 GDSC1; GDSC2 2.4465 6.1545 1.593 19.1426
TE-10 GDSC1; GDSC2; CTRP2 3.1592 7.9506 2.2281 22.5957
KYSE-520 GDSC1; GDSC2; CTRP2 3.2012 10.1329 1.3257 25.6645
OE33 GDSC1; GDSC2; CTRP2 3.2461 9.9925 1.4346 25.1744
KYSE-140 GDSC1; GDSC2; CTRP2 3.4317 8.6674 2.2124 21.8946
KYSE-410 GDSC1; GDSC2; CTRP2 3.4375 9.2631 1.9565 22.8175
TE-6 GDSC1; GDSC2; CTRP2 3.7641 14.3354 -0.1269 28.5079
KYSE-70 GDSC1; GDSC2; CTRP2 3.853 8.1508 2.8707 18.2594
TE-4 GDSC1; GDSC2; CTRP2 3.8669 10.9607 1.5987 22.9627
KYSE-180 GDSC1; GDSC2; CTRP2 4.5363 10.881 2.2775 18.8283
T.T GDSC1; GDSC2 4.9981 12.6574 0.7035 16.3663
TE-11 GDSC1; GDSC2; CTRP2 5.0413 7.7907 4.24 9.7722
EC-GI-10 GDSC1; GDSC2; CTRP2 5.1532 10.9751 2.8019 15.3677
KYSE-450 GDSC1; GDSC2; CTRP2 5.4528 11.2473 2.9348 14.1852
TE-14 CTRP2 5.7098 9.939 3.8117 10.0452
TE-9 GDSC1; GDSC2; CTRP2 5.7424 10.1675 3.7261 10.3346
TE-8 GDSC1; GDSC2 6.0861 15.0759 0.3349 15.6134
OE19 GDSC1; GDSC2; CTRP2 6.2655 8.2111 5.1394 3.3982
TE-1 GDSC1; GDSC2; CTRP2 6.2883 13.2325 2.6515 13.6296
COLO 680N GDSC1; GDSC2; CTRP2 6.3514 15.0979 1.7709 16.8195
KYSE-30 CTRP2 7.0158 12.7522 3.4617 9.0812
KYSE-150 GDSC1; GDSC2; CTRP2 7.436 23.0089 -1.3079 23.8699
KYSE-510 GDSC1; GDSC2; CTRP2 10.2836 22.6816 0.9383 13.3074
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.2408 7.7549 3.4423 15.0013
DAN-G GDSC1; GDSC2; CTRP2 1.7785 7.0536 1.0788 30.7388
KP-4 GDSC1; GDSC2; CTRP2 1.9574 6.7007 1.3891 29.1545
HPAF-II GDSC1; GDSC2; CTRP2 1.9805 7.5389 1.1272 29.934
SNU-213 CTRP2 2.0038 7.9434 1.002 30.2551
Panc 10.05 GDSC1; GDSC2; CTRP2 2.2903 8.0903 1.2512 28.5645
HuP-T4 GDSC1; GDSC2; CTRP2 2.3509 9.6311 0.6796 30.155
Panc 08.13 GDSC1; GDSC2; CTRP2 2.5448 8.6923 1.2782 27.7052
PK-59 CTRP2 2.6218 6.7923 2.0812 24.7021
BxPC-3 GDSC1; GDSC2; CTRP2 2.9266 8.5938 1.719 25.0905
Panc 03.27 GDSC1; GDSC2; CTRP2 3.0364 6.5589 2.608 21.5558
PSN1 GDSC1; GDSC2; CTRP2 3.1875 10.136 1.3104 25.7536
L3.3 CTRP2 3.2513 6.941 2.7116 20.5419
PaTu 8988t GDSC1; GDSC2; CTRP2 3.384 12.247 0.5197 27.695
TCC-Pan2 CTRP2 3.4082 8.2111 2.3825 21.326
Hs 766T GDSC1; GDSC2; CTRP2 3.4612 9.2422 1.9899 22.6319
MZ-PC-1 GDSC1; GDSC2 3.6432 6.1179 2.8104 9.4982
MIA PaCa-2 GDSC1; GDSC2; CTRP2 3.7054 8.0802 2.7475 19.1308
CFPAC-1 GDSC1; GDSC2; CTRP2 3.8923 11.7576 1.2428 24.1125
SW1990 GDSC1; GDSC2; CTRP2 4.1297 10.2502 2.1908 20.1487
QGP-1 GDSC1; GDSC2; CTRP2 4.4001 9.4539 2.8307 17.0113
KP-3 GDSC1; GDSC2; CTRP2 4.422 8.6938 3.2069 15.4652
YAPC GDSC1; GDSC2; CTRP2 4.6428 10.9871 2.3259 18.3918
SU.86.86 GDSC1; GDSC2; CTRP2 4.717 9.1916 3.2629 14.5174
Panc 05.04 CTRP2 4.7973 14.6708 0.6524 23.8242
PaTu 8902 GDSC1; GDSC2; CTRP2 5.0167 12.2292 2.0587 18.5416
AsPC-1 GDSC1; GDSC2; CTRP2 5.162 11.1467 2.7251 15.6529
Panc 04.03 GDSC1; GDSC2; CTRP2 5.1653 11.8177 2.396 16.9327
SUIT-2 GDSC1; GDSC2; CTRP2 5.337 10.2734 3.3149 12.8899
KP-1N GDSC2 5.6531 8.5944 2.2816 1.9089
PaTu 8988s CTRP2 5.7396 9.3363 4.1381 8.6199
Capan-1 GDSC1; GDSC2; CTRP2 5.8355 16.3759 0.7035 21.4275
Capan-2 GDSC1; GDSC2; CTRP2 6.0899 15.7116 1.2487 19.1481
PK-45H CTRP2 6.3848 12.6991 2.9963 12.0788
HPAC GDSC1; GDSC2; CTRP2 6.5631 16.0365 1.4738 17.461
SNU-410 CTRP2 6.6114 20.455 -0.694 23.8481
KP-2 GDSC1; GDSC2; CTRP2 6.7744 12.3119 3.4963 9.3492
Panc 02.03 GDSC1; GDSC2; CTRP2 6.8112 13.2923 3.038 11.1391
HuP-T3 GDSC1; GDSC2; CTRP2 6.8337 16.6321 1.3931 17.2327
PL4 GDSC1; GDSC2 7.5242 16.8644 0.4768 12.4264
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 4.5305 10.6408 2.3884 18.4189
G-mel GDSC1; GDSC2 -1.2137 5.6712 -2.135 50.3408
A-431 GDSC1; GDSC2 -0.9946 8.6945 -3.0644 49.164
CHL-1 GDSC1; GDSC2 -0.8872 6.1338 -1.9436 44.354
MZ-MEL-2 GDSC1; GDSC2 -0.1836 6.516 -1.3299 43.6485
WM35 GDSC1; GDSC2 -0.1761 5.5908 -0.9839 39.0762
WM88 CTRP2 -0.0103 6.5087 -0.6956 41.8083
WM115 GDSC1; GDSC2; CTRP2 0.5162 7.8705 -0.5702 39.4659
RPMI-7951 GDSC1; GDSC2; CTRP2 0.7266 11.0289 -1.6026 40.4184
Hs 852.T CTRP2 1.6212 7.7651 0.6581 32.5329
WM1552C GDSC1; GDSC2 1.6261 9.875 -0.9296 31.7908
COLO 679 GDSC1; GDSC2 1.7042 7.7752 0.118 28.0044
Mel Ho GDSC1; GDSC2; CTRP2 1.7486 5.742 1.4353 29.6743
WM266-4 CTRP2 1.7873 9.0899 0.3188 32.9347
A-388 GDSC1; GDSC2 1.8308 11.3676 -1.4442 35.1512
MZ-MEL-7 GDSC1; GDSC2 1.9043 6.1212 1.0417 26.2175
IST-MEL1 GDSC1; GDSC2 2.1301 7.8645 0.5055 25.0229
451Lu GDSC1; GDSC2 2.5394 10.9023 -0.5506 30.1531
SH-4 GDSC1; GDSC2 2.553 12.0615 -1.1055 29.3715
Hs 944.T CTRP2 2.7366 8.8489 1.4135 26.6896
LOX-IMVI GDSC1; GDSC2; CTRP2 2.8639 6.7113 2.3709 22.9328
GAK GDSC1; GDSC2 2.8886 8.8691 0.7659 21.5396
IPC-298 GDSC1; GDSC2; CTRP2 2.9196 10.1233 1.0456 27.3662
SK-MEL-5 GDSC1; GDSC2; CTRP2 2.9331 6.982 2.3535 22.7907
Hs 940.T GDSC1; GDSC2; CTRP2 2.9635 10.1898 1.0602 27.1952
COLO 792 GDSC1; GDSC2; CTRP2 3.102 8.0367 2.1329 23.1071
Mel JuSo GDSC1; GDSC2; CTRP2 3.2129 6.7886 2.7232 20.6112
CP50-MEL-B GDSC1; GDSC2 3.5851 15.814 -2.0492 31.1565
WM793 GDSC1; GDSC2; CTRP2 3.6159 10.7058 1.4738 24.0467
SK-MEL-3 GDSC1; GDSC2; CTRP2 3.6364 11.6335 1.0558 25.383
Hs 294T CTRP2 3.8542 7.8808 2.9868 17.8085
UACC-62 GDSC1; GDSC2; CTRP2 3.9254 10.9691 1.6514 22.6283
COLO 741 CTRP2 4.0863 12.1169 1.2539 23.5885
COLO 829 GDSC1; GDSC2; CTRP2 4.1052 11.314 1.6593 22.1481
WM983B CTRP2 4.1718 9.0091 2.8123 17.655
DJM-1 GDSC1; GDSC2 4.2984 8.8938 2.0163 13.227
IGR-39 CTRP2 4.3555 8.2699 3.3332 15.1323
MDA-MB-435S CTRP2 4.4761 9.2421 3.0048 16.1356
A-375 GDSC1; GDSC2; CTRP2 4.596 9.5694 2.966 15.9982
G-361 GDSC1; GDSC2; CTRP2 4.6056 7.8959 3.7547 12.8163
SK-MEL-30 GDSC1; GDSC2; CTRP2 4.6228 9.5871 2.9834 15.8647
RVH-421 GDSC1; GDSC2; CTRP2 4.6544 9.0894 3.2508 14.7171
MeWo GDSC1; GDSC2; CTRP2 4.7018 14.3403 0.7305 23.8021
HMCB CTRP2 4.7253 9.0998 3.3147 14.2887
WM1799 CTRP2 4.741 17.1117 -0.6097 27.4404
COLO 800 GDSC1; GDSC2; CTRP2 4.7503 11.1592 2.342 18.0791
HMV-II GDSC1; GDSC2 4.8106 15.1197 -0.6753 22.1023
HT-144 GDSC1; GDSC2; CTRP2 4.8158 11.1149 2.4243 17.6111
K029AX CTRP2 4.8891 10.6603 2.7148 16.3081
SK-MEL-24 GDSC1; GDSC2; CTRP2 5.1251 11.8653 2.3363 17.2508
CJM [Human melanoma] CTRP2 5.2221 7.9749 4.3304 8.9664
CP66-MEL GDSC1; GDSC2 5.2251 13.9216 0.2524 19.38
SK-MEL-1 GDSC1; GDSC2; CTRP2 5.2939 13.5767 1.6359 19.4667
IGR-37 GDSC1; GDSC2; CTRP2 5.3507 8.244 4.3239 8.6921
Hs 895.T CTRP2 5.3737 12.2773 2.3527 16.6454
WM278 GDSC1; GDSC2 5.4647 7.5262 3.5422 1.9787
IGR-1 GDSC1; GDSC2; CTRP2 5.6239 7.8115 4.7899 6.145
VMRC-MELG GDSC1; GDSC2 5.7499 8.1378 3.4316 2.359
A2058 GDSC1; GDSC2; CTRP2 5.7868 9.5416 4.0768 8.7793
Hs 839.T CTRP2 6.012 15.7807 1.1492 19.6364
UACC-257 GDSC1; GDSC2; CTRP2 6.1114 12.1057 3.0694 12.3041
M14 GDSC1; GDSC2 6.2091 7.8239 3.7849 0.442
SK-MEL-2 GDSC1; GDSC2; CTRP2 6.3163 7.6073 5.4764 1.9113
LB2518-MEL GDSC1; GDSC2 6.4008 7.6737 3.9124 0.1441
SK-MEL-28 GDSC1; GDSC2; CTRP2 6.4371 16.7202 1.0301 19.1919
A101D GDSC1; GDSC2; CTRP2 6.5269 9.1734 4.8616 4.1145
MMAc-SF GDSC1; GDSC2 7.0727 19.2443 -0.9895 19.9374
Hs 688(A).T CTRP2 7.3648 13.9342 3.1386 9.8055
Hs 934.T CTRP2 7.6364 13.5806 3.5065 7.9198
Hs 938.T GDSC1; GDSC2 7.8086 20.6875 -1.1687 19.1247
WT2-iPS GDSC1; GDSC2; CTRP2 7.8378 15.6025 2.665 10.8931
COLO 783 GDSC1; GDSC2 7.8573 22.3461 -1.9407 21.373
SK-MEL-31 GDSC2; CTRP2 8.238 20.8883 0.3618 18.0862
Hs 936.T CTRP2 8.2473 15.578 2.9651 9.1314
LB373-MEL-D GDSC1; GDSC2 8.7057 19.3823 0.0564 13.2467
Malme-3M CTRP2 8.8235 11.1899 5.2578 0.5239
EquiPSC Line K2 GDSC1; GDSC2 2.1928 15.2711 -3.0146 37.1109
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYAE-1 GDSC1; GDSC2 -0.7072 6.4963 -1.883 43.3745
OACM5.1 C GDSC1; GDSC2 -0.1383 5.5962 -0.9448 38.8021
KYSE-50 GDSC1; GDSC2 1.2928 8.8912 -0.8027 32.5811
SK-GT-4 GDSC1; GDSC2 1.4711 8.7974 -0.5812 31.2629
OACP4 C GDSC1; GDSC2 1.8426 7.1106 0.5548 25.7908
TE-12 GDSC1; GDSC2 1.9734 7.1798 0.6578 27.6779
FLO-1 GDSC1; GDSC2 2.7168 12.4513 -1.1473 29.0151
KYSE-220 GDSC1; GDSC2 2.8212 10.1221 0.0927 24.5029
ESO-26 GDSC1; GDSC2 3.2178 9.0277 0.9956 19.5642
ESO-51 GDSC1; GDSC2 3.7894 8.4212 1.8132 14.1309
HCE-4 GDSC1; GDSC2 7.1152 16.084 0.5745 13.9459
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 0.8231 6.4116 0.2419 36.4741
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-YS GDSC1; GDSC2 -1.373 4.579 -1.9652 51.4849
SK-N-MC-IXC GDSC1; GDSC2 -1.2191 2.9168 -1.4076 50.4784
SJNB-7 GDSC1; GDSC2 -0.9319 2.8055 -1.0802 43.1561
NB69 GDSC1; GDSC2 -0.8645 6.9647 -2.2289 44.585
IMR-32 CTRP2 -0.4572 3.7214 -0.5779 43.5795
SJNB-6 GDSC1; GDSC2 0.9768 12.3956 -2.7556 40.6769
SJNB-17 GDSC1; GDSC2 1.0758 7.2819 -0.3107 35.0721
SJNB-13 GDSC1; GDSC2 1.6672 7.0762 0.3896 27.0758
KP-N-SI9s CTRP2 1.6844 7.1898 0.9306 31.5099
NH-12 GDSC1; GDSC2 1.8613 9.5138 -0.5296 29.7548
SK-N-BE(2) CTRP2 1.9249 10.9606 -0.3398 34.1407
Kelly GDSC1; GDSC2; CTRP2 2.0898 9.489 0.4693 31.5611
NB1 GDSC1; CTRP2 2.2157 5.7495 1.9428 26.4446
SJNB-10 GDSC1; GDSC2 2.3301 10.7673 -0.6811 28.7371
SJNB-5 GDSC1; GDSC2 2.3761 7.8993 0.7334 25.8134
SK-N-SH GDSC1; GDSC2; CTRP2 2.5644 8.6688 1.3085 27.5473
TGW GDSC1; GDSC2 2.592 8.4001 0.7081 22.6904
IMR-5 GDSC1; GDSC2 2.6333 9.4926 0.2227 24.5629
SK-N-AS GDSC1; GDSC2; CTRP2 2.903 7.331 2.1952 23.4552
MHH-NB-11 GDSC1; GDSC2; CTRP2 3.0451 9.5209 1.4418 25.7092
SiMa GDSC1; GDSC2 3.1265 10.4512 0.2117 23.1479
CHP-212 GDSC1; GDSC2; CTRP2 3.166 9.0728 1.7624 24.2599
GI-ME-N GDSC1; GDSC2 3.5217 10.1978 0.6931 20.0531
SK-N-FI GDSC1; GDSC2; CTRP2 3.6454 10.9647 1.3812 24.2845
SK-N-DZ GDSC1; GDSC2; CTRP2 3.659 6.0543 3.4385 16.6635
CHP-134 GDSC1; GDSC2 3.6593 9.3834 1.2198 17.3207
CHP-126 GDSC1; GDSC2; CTRP2 3.8384 11.1652 1.474 23.4681
SK-N-BE(2)-M17 GDSC1; GDSC2 3.9551 8.8829 1.729 14.1162
SJNB-14 GDSC1; GDSC2 4.0781 13.395 -0.4194 22.9683
GOTO GDSC1; GDSC2 4.3834 10.9985 1.0347 16.3333
SJNB-12 GDSC1; GDSC2 4.5246 16.226 -1.4621 25.26
NH-6 CTRP2 4.9848 9.3267 3.454 13.111
LA-N-6 GDSC1; GDSC2 5.7342 12.1686 1.5043 12.4538
NB(TU)1 GDSC1; GDSC2 6.1837 15.0698 0.4096 15.122
KP-N-RT-BM-1 GDSC2 6.5036 8.4206 2.7059 0.2253
KP-N-YN GDSC1; CTRP2 8.8042 15.9189 3.1741 7.5729
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 0.3036 4.145 0.1772 38.6168
SNU-478 CTRP2 1.4945 7.6044 0.5799 33.1823
HuCC-T1 GDSC1; GDSC2; CTRP2 1.6581 6.8937 1.0013 31.3778
HuH-28 CTRP2 4.6059 10.9518 2.3086 18.5448
SNU-869 CTRP2 4.6953 10.1266 2.7931 16.4489
SNU-1196 CTRP2 4.7865 10.356 2.7677 16.3357
SNU-308 CTRP2 5.4789 12.9726 2.0984 17.3847
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MRK-nu-1 GDSC1; GDSC2 -1.6631 0.8926 -1.6765 48.5862
OCUB-M GDSC1; GDSC2 -0.9582 1.6482 -0.9856 42.938
ZR-75-1 CTRP2 0.4753 7.5899 -0.5159 39.5177
UACC-893 GDSC1; GDSC2 0.4998 6.2127 -0.4839 34.5981
YMB-1-E GDSC1; GDSC2 0.5027 11.081 -2.5993 42.246
MDA-MB-453 GDSC1; GDSC2; CTRP2 1.024 6.4628 0.4457 35.1963
HCC1500 GDSC1; GDSC2; CTRP2 1.2617 11.5613 -1.2832 38.1382
MDA-MB-330 GDSC1; GDSC2 1.3394 10.1925 -1.3597 33.887
HCC2157 GDSC1; GDSC2 1.592 8.8717 -0.4948 30.4877
CAL-148 GDSC1; GDSC2; CTRP2 1.6367 5.9599 1.257 30.6306
MDA-MB-468 GDSC1; GDSC2; CTRP2 1.6993 5.9845 1.3187 30.2223
MDA-MB-175-VII GDSC1; GDSC2 1.8029 9.2314 -0.4538 29.6312
HCC1954 GDSC1; GDSC2; CTRP2 1.846 6.686 1.2726 29.8964
Hs 578T GDSC1; GDSC2; CTRP2 1.8602 6.9124 1.2146 30.0391
DU4475 GDSC1; GDSC2; CTRP2 1.9143 4.6656 1.825 27.8165
T-47D GDSC1; GDSC2; CTRP2 1.9481 8.0219 0.9126 30.7089
MDA-MB-361 GDSC1; GDSC2; CTRP2 1.9586 9.1569 0.4711 31.9685
HCC1599 GDSC1; GDSC2 2.1976 5.3833 1.6468 19.6758
CAL-85-1 GDSC1; GDSC2; CTRP2 2.228 8.2797 1.1107 29.2095
HCC1569 GDSC1; GDSC2 2.2407 9.6582 -0.2311 27.4286
EFM-192A GDSC1; GDSC2; CTRP2 2.2615 6.1768 1.8791 26.5225
HCC202 CTRP2 2.6205 9.0883 1.1913 27.7643
HCC1419 GDSC1; GDSC2; CTRP2 2.738 9.3447 1.2033 27.3809
HCC70 GDSC1; GDSC2 2.7473 8.1155 0.9937 20.9032
HCC38 GDSC1; GDSC2; CTRP2 2.7541 8.7366 1.479 26.4173
Evsa-T GDSC1; GDSC2 2.8776 9.1889 0.6003 22.2257
CAL-51 GDSC1; GDSC2; CTRP2 2.9093 9.749 1.2021 26.891
HCC1187 GDSC1; GDSC2 2.9243 8.3468 1.0522 20.1084
CAMA-1 GDSC1; GDSC2; CTRP2 2.9395 11.0128 0.661 28.493
BT-483 GDSC1; GDSC2 2.9543 9.1071 0.712 21.5226
MDA-MB-157 GDSC1; GDSC2; CTRP2 3.0516 11.463 0.564 28.4662
BT-549 GDSC1; GDSC2; CTRP2 3.0556 10.7427 0.9012 27.4377
HCC1143 GDSC2; CTRP2 3.19 7.1984 2.5525 21.3091
CAL-120 GDSC1; GDSC2; CTRP2 3.4967 7.7456 2.6673 20.0094
EFM-19 GDSC1; GDSC2 3.679 12.3329 -0.2312 23.2645
MCF-7 GDSC1; GDSC2; CTRP2 3.688 7.7894 2.8509 18.7831
JIMT-1 GDSC1; GDSC2; CTRP2 3.8646 10.3231 1.8975 21.9039
HCC2218 GDSC1; GDSC2; CTRP2 3.9103 11.3296 1.465 23.3156
COLO 824 GDSC1; GDSC2 4.1372 9.7682 1.4433 14.998
AU565 GDSC1; GDSC2; CTRP2 4.169 11.9484 1.4137 22.844
ZR-75-30 GDSC1; GDSC2; CTRP2 4.2022 10.7022 2.0457 20.509
HCC1428 GDSC1; GDSC2; CTRP2 4.2219 11.5674 1.6482 21.8989
BT-474 GDSC1; GDSC2; CTRP2 4.2616 12.0292 1.4616 22.4525
HCC1395 GDSC1; GDSC2; CTRP2 4.2855 10.1587 2.3854 19.0245
BT-20 GDSC1; GDSC2; CTRP2 4.2998 11.1769 1.9106 20.7657
HCC1937 GDSC1; GDSC2; CTRP2 4.4717 13.7284 0.8241 24.0467
MFM-223 GDSC1; GDSC2 4.5121 13.4911 -0.1051 20.708
HCC1806 GDSC1; GDSC2; CTRP2 4.9753 11.3907 2.4352 17.2052
Hs 578Bst CTRP2 5.2486 22.5571 -2.8841 41.6525
MDA-MB-231 GDSC1; GDSC2; CTRP2 5.3632 15.304 0.8353 22.0033
HMC-1-8 CTRP2 5.686 13.9086 1.8098 18.0115
UACC-812 GDSC1; GDSC2 5.7808 12.3244 1.4618 11.3156
HDQ-P1 GDSC1; GDSC2; CTRP2 5.8425 16.0177 0.8885 20.8293
KPL-1 CTRP2 6.1482 7.3824 5.4598 2.2639
MDA-MB-436 GDSC1; GDSC2 6.869 15.6343 0.6221 12.9579
MDA-MB-415 GDSC1; GDSC2 8.8362 19.2452 0.203 11.4544
BT 145 CTRP2 1.4529 8.0234 0.3818 33.873
BT164 CTRP2 2.1944 9.3071 0.6551 30.7052
BT 271 CTRP2 2.2928 7.7424 1.3872 28.1087
BT 131 CTRP2 2.4709 9.1377 1.0147 28.7732
BT 231 CTRP2 3.058 9.2684 1.566 25.2486
BT 112 CTRP2 3.0859 9.6475 1.4273 25.6438
BT 330 CTRP2 3.1034 12.7804 -0.0056 29.9055
BT147 CTRP2 3.1517 9.1038 1.7343 24.3988
BT 248 CTRP2 3.4112 10.7512 1.2508 25.3421
BT 239 CTRP2 3.6056 10.4285 1.5931 23.6611
BT 440 CTRP2 3.6367 13.1721 0.3181 27.6161
BT 428 CTRP2 3.8716 7.5286 3.1507 17.1299
BT 416 CTRP2 4.1408 7.181 3.5749 14.758
BT 245 CTRP2 4.2927 14.4011 0.3293 25.9611
BT 232 CTRP2 4.6189 11.9874 1.8148 20.3501
BT 179 CTRP2 4.6326 13.948 0.8621 23.5503
BT 172 CTRP2 4.7131 9.1099 3.298 14.3855
BT 359 CTRP2 4.7784 10.9313 2.4796 17.4838
BT 444 CTRP2 4.8173 14.6875 0.662 23.7492
BT 159 CTRP2 4.8575 13.1659 1.4518 21.0815
BT 286 CTRP2 4.8695 9.3199 3.3478 13.8123
BT 498 CTRP2 5.0402 14.8826 0.7629 22.9366
BT 216 CTRP2 5.1649 11.5169 2.5445 16.3571
BT 422 CTRP2 5.3766 14.1289 1.433 19.997
BT 482 CTRP2 5.4039 14.0662 1.488 19.748
BT 504 CTRP2 5.8325 16.6586 0.5597 21.8765
BT 224 CTRP2 5.8358 13.0601 2.3613 15.6472
BT 333 CTRP2 6.105 17.4834 0.3753 21.8829
BT 340 CTRP2 6.3156 16.8009 0.8905 19.8786
BT 328 CTRP2 6.3778 22.1051 -1.7098 26.6697
BT 228 CTRP2 6.5367 13.2441 2.8462 12.3965
BT 139 CTRP2 7.8453 15.8324 2.558 11.2864
BT 320 CTRP2 8.4561 17.6956 2.0858 12.0802
BT 187 CTRP2 10.5702 24.4933 0.2647 14.931
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 2.6929 6.5554 2.2355 23.9351
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-1 GDSC1; GDSC2 -1.0991 4.9321 -1.7714 45.263
PFSK-1 GDSC1 -0.6437 28.067 -11.9062 51.8324
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -0.6204 4.1316 -1.021 41.3497
D-423MG GDSC1; GDSC2 -0.5507 6.9609 -1.8929 46.306
MOG-G-CCM GDSC1; GDSC2 0.0398 6.9811 -1.274 38.7857
D-566MG GDSC1; GDSC2 0.3256 8.9003 -1.7869 41.8497
D-336MG GDSC1; GDSC2 0.9245 8.1205 -0.8301 37.2197
MOG-G-UVW GDSC1; GDSC2 1.0491 6.2303 0.0943 30.4973
H4 GDSC1; GDSC2 1.26 8.2102 -0.5276 31.8518
D283 Med GDSC1; GDSC2; CTRP2 1.434 4.9167 1.2699 31.2608
D-502MG GDSC1; GDSC2 1.8311 7.6839 0.2875 29.7719
D-247MG GDSC1; GDSC2 1.8782 6.8591 0.7014 27.865
AM-38 GDSC1; GDSC2 2.265 6.2036 1.3838 20.7147
M059J GDSC1; GDSC2 2.519 7.6336 0.9983 21.6462
YKG-1 GDSC1; GDSC2; CTRP2 2.5338 7.3054 1.8075 25.9366
U-87MG ATCC GDSC1; GDSC2; CTRP2 2.5439 9.2089 1.0604 28.411
LN-405 GDSC1; GDSC2 2.6572 9.7696 0.1111 24.9251
KALS-1 GDSC1; GDSC2; CTRP2 2.7076 10.0096 0.8807 28.4913
D-392MG GDSC1; GDSC2 2.7431 12.4793 -1.1372 28.9093
SF539 GDSC1; GDSC2; CTRP2 2.9391 6.3694 2.5615 22.0164
Becker GDSC1; GDSC2; CTRP2 2.9438 7.8176 2.0529 23.8516
ONS-76 GDSC1; GDSC2; CTRP2 2.9542 6.1967 2.6292 21.7263
LNZTA3WT4 GDSC1; GDSC2 3.057 9.9603 0.3898 22.6315
SF295 GDSC1; GDSC2; CTRP2 3.1243 8.3974 2.0079 23.4983
Onda 10 GDSC1; GDSC2 3.2445 9.1104 0.9796 21.6892
YH-13 GDSC1; GDSC2; CTRP2 3.2528 10.0883 1.3979 25.2805
Onda 11 GDSC1; GDSC2 3.5969 9.5637 1.0748 20.1286
SNU-489 CTRP2 3.7474 10.9415 1.4916 23.6419
SW1088 GDSC1; GDSC2; CTRP2 3.8117 10.4194 1.8004 22.3904
U-118MG GDSC1; GDSC2; CTRP2 3.8342 8.7295 2.598 19.359
GB-1 GDSC1; GDSC2; CTRP2 3.8876 11.4828 1.3699 23.6974
Daoy GDSC1; GDSC2; CTRP2 3.928 9.3307 2.4211 19.7904
GaMG GDSC1; GDSC2; CTRP2 3.9602 11.3774 1.49 23.1029
SNU-1105 CTRP2 3.9986 9.8663 2.2431 20.2832
SNU-738 CTRP2 4.2511 9.1223 2.839 17.3499
CAS-1 GDSC1; GDSC2; CTRP2 4.2759 10.8835 2.0293 20.3884
KNS-81 CTRP2 4.2797 16.5758 -0.7557 28.8404
KINGS-1 GDSC1; GDSC2 4.3035 11.1474 0.8938 17.1581
KNS-81-FD GDSC1; GDSC2 4.3878 8.3721 2.3514 11.1278
42-MG-BA GDSC1; GDSC2; CTRP2 4.429 11.8397 1.7107 21.1744
Hs 683 GDSC1; GDSC2; CTRP2 4.5377 7.6718 3.7846 12.8733
SF126 GDSC1; GDSC2; CTRP2 4.6349 13.2937 1.1871 22.4913
SW1783 GDSC1; GDSC2; CTRP2 4.7603 12.3559 1.7636 20.2053
D-245MG GDSC2 4.928 9.1321 1.6215 6.8489
DBTRG-05MG GDSC1; GDSC2; CTRP2 4.9525 10.3322 2.9341 15.2904
T98G GDSC1; GDSC2; CTRP2 5.0074 11.0165 2.6489 16.2992
M059K CTRP2 5.0309 10.0491 3.1454 14.2609
LN-18 GDSC1; GDSC2; CTRP2 5.0538 8.5925 3.8734 11.2348
SF268 GDSC1; GDSC2; CTRP2 5.0793 9.5473 3.4355 12.9693
GOS-3 CTRP2 5.2268 9.1226 3.7801 11.2188
A-172 GDSC1; GDSC2; CTRP2 5.2452 11.1558 2.7955 15.1906
SNU-201 CTRP2 5.3142 12.5869 2.1463 17.5581
LN-229 GDSC1; GDSC2; CTRP2 5.3294 10.8348 3.03 14.0662
D-542MG GDSC1; GDSC2 5.3656 15.3845 -0.3654 21.4528
DK-MG GDSC1; GDSC2; CTRP2 5.3878 12.5633 2.2228 17.1108
GMS-10 CTRP2 5.3984 11.1316 2.9442 14.2636
D-263MG GDSC1; GDSC2 5.4659 7.2526 3.6644 1.4498
SNB-75 GDSC1; GDSC2; CTRP2 5.4978 12.0178 2.5908 15.4568
CCF-STTG1 CTRP2 5.5887 10.302 3.5248 11.4881
NMC-G1 GDSC1; GDSC2; CTRP2 5.6658 8.9025 4.2887 8.1441
KG-1-C CTRP2 5.7253 13.7862 1.9045 17.5856
TM-31 CTRP2 5.7868 11.8398 2.9294 13.5129
KNS-60 CTRP2 5.8269 19.7989 -1.0149 26.1478
SNU-626 CTRP2 5.9796 11.5894 3.2177 11.9583
8-MG-BA GDSC1; GDSC2; CTRP2 6.2868 12.3731 3.0797 11.9269
SK-MG-1 GDSC1; GDSC2 6.4097 16.2924 -0.0251 16.3865
U-251MG GDSC1; GDSC2; CTRP2 6.9319 13.0496 3.2511 10.0744
SNU-466 CTRP2 8.8576 20.854 0.8331 15.6714
KNS-42 GDSC1; GDSC2; CTRP2 10.3468 21.0355 1.7594 10.5972
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 3.5252 12.8901 -0.643 25.1723
ETK-1 GDSC1; GDSC2 3.9198 9.7104 1.2856 16.3315
TGBC1TKB GDSC1; GDSC2 5.0215 11.1329 1.4805 12.8109
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC1; GDSC2 -0.0042 7.9293 -1.7092 39.8849
AN3-CA GDSC1; GDSC2; CTRP2 1.4715 7.1666 0.7078 32.8908
JHUEM-2 CTRP2 1.6518 5.0577 1.4794 29.8433
JHUEM-1 CTRP2 2.2318 6.1815 1.8454 26.7329
JHUEM-3 CTRP2 2.8828 7.2222 2.2135 23.4478
HEC-59 CTRP2 3.0984 9.2532 1.6142 24.9683
JHUEM-7 CTRP2 3.1394 6.9333 2.5935 21.3048
HEC-1-B CTRP2 3.1791 8.4409 2.0468 23.2026
HEC-151 CTRP2 3.4168 6.9518 2.8863 19.4127
ESS-1 GDSC1; GDSC2; CTRP2 3.58 9.0328 2.2041 21.5235
HEC-1-A CTRP2 3.5842 8.58 2.4076 20.7504
HEC-108 CTRP2 3.6043 9.61 1.9689 22.3248
MFE-296 GDSC1; GDSC2; CTRP2 3.8045 10.9189 1.558 23.2648
HEC-6 CTRP2 3.888 8.3841 2.8056 18.4175
KLE GDSC1; GDSC2; CTRP2 3.9809 12.8165 0.8154 25.2655
RL95-2 GDSC1; GDSC2; CTRP2 4.1251 9.5627 2.5096 18.9482
HEC-50B CTRP2 4.2222 10.5854 2.1208 20.1808
MFE-319 GDSC1; GDSC2; CTRP2 4.911 7.7071 4.1484 10.4662
EFE-184 CTRP2 4.9303 8.7609 3.674 12.341
EN GDSC1; GDSC2; CTRP2 5.0112 13.3873 1.48 20.6367
HEC-251 CTRP2 5.0228 13.8096 1.2807 21.2926
HEC-265 CTRP2 5.827 9.2118 4.2761 7.8627
Ishikawa (Heraklio) 02 ER- CTRP2 3.8998 14.1835 0.0736 27.6339
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-1M GDSC1; GDSC2 -2.2419 2.5531 -2.4475 58.3342
KTCTL-21 GDSC1; GDSC2 -1.7839 3.9878 -2.2534 54.422
KTCTL-140 GDSC1; GDSC2 -1.1279 4.1227 -1.5724 49.7564
KTCTL-195 GDSC1; GDSC2 -0.3953 6.5863 -1.5829 41.39
NCC021 GDSC1; GDSC2 0.2626 17.2142 -5.7561 45.5842
LB1047-RCC GDSC1; GDSC2 0.6621 6.7476 -0.5221 37.6051
KTCTL-26A GDSC1; GDSC2 0.7974 6.8069 -0.4035 36.6253
TK-10 GDSC1; GDSC2 1.2949 8.6549 -0.6929 32.2421
UO-31 GDSC1; GDSC2; CTRP2 2.1091 8.9726 0.7053 30.8227
CAL-54 GDSC1; GDSC2; CTRP2 2.8164 8.5862 1.6069 25.7983
BB65-RCC GDSC1; GDSC2 3.189 13.2637 -1.125 29.8372
RXF 393L GDSC1; GDSC2 3.2196 11.1065 -0.0277 26.0685
HA7-RCC GDSC1; GDSC2 3.3303 11.0472 0.101 25.222
SW156 GDSC1; GDSC2 3.799 12.2822 -0.102 24.5915
KTCTL-13 GDSC1; GDSC2 3.8209 14.45 -1.1654 28.1225
769-P GDSC1; GDSC2; CTRP2 4.1338 10.9624 1.8555 21.3751
OS-RC-2 GDSC1; GDSC2; CTRP2 4.3486 12.2141 1.4531 22.2709
A-704 GDSC1; GDSC2 4.4411 6.4475 3.3568 4.682
ACHN GDSC1; GDSC2; CTRP2 4.6836 11.3711 2.1765 18.8629
KMRC-2 CTRP2 4.7477 10.0389 2.8851 15.9602
KMRC-1 GDSC1; GDSC2; CTRP2 4.9473 11.2891 2.4597 17.1737
Caki-1 GDSC1; GDSC2; CTRP2 5.0413 12.1788 2.1058 18.3108
TUHR10TKB CTRP2 5.0591 8.0736 4.1252 10.1944
VMRC-RCZ GDSC1; GDSC2; CTRP2 5.0909 14.4176 1.0388 21.9432
786-O GDSC1; GDSC2; CTRP2 5.1217 8.9096 3.7853 11.4373
BFTC-909 GDSC1; GDSC2; CTRP2 5.1591 11.8361 2.3812 17.0031
NCC010 GDSC2 5.2154 10.4762 1.173 8.816
A-498 GDSC1; GDSC2; CTRP2 5.232 11.25 2.737 15.452
SW13 GDSC1; GDSC2 5.9548 17.5156 -0.9684 20.6149
KMRC-3 CTRP2 6.203 12.3035 3.046 12.2225
KMRC-20 GDSC1; GDSC2; CTRP2 6.2045 12.8902 2.754 13.3869
LB2241-RCC GDSC1; GDSC2 6.216 8.596 3.4808 1.5846
LB996-RCC GDSC1; GDSC2 6.4505 15.6157 0.3357 14.9079
TUHR4TKB CTRP2 6.462 14.8626 1.9783 15.8556
SNU-1272 CTRP2 6.513 15.8272 1.5378 17.334
VMRC-RCW GDSC1; GDSC2; CTRP2 6.5161 9.57 4.6576 4.9794
Caki-2 CTRP2 7.0152 11.9767 3.8433 7.5258
SN12C GDSC1; GDSC2 7.097 16.4573 0.3823 13.5511
TUHR14TKB CTRP2 7.1428 9.5884 5.0827 2.3494
RCC10RGB GDSC1; GDSC2; CTRP2 9.7329 22.8439 0.4846 15.4425
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 60 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CL-34 CTRP2 1.6147 6.4179 1.1032 31.2001
SW837 GDSC1; GDSC2 2.3729 7.8409 0.7574 23.1697
SNU-81 GDSC1; GDSC2; CTRP2 2.3763 7.7688 1.4666 27.5869
SW48 GDSC1; GDSC2; CTRP2 2.4669 10.0337 0.6239 29.9696
SW626 GDSC1; GDSC2 2.4886 5.8349 1.7727 18.1605
SW1463 GDSC1; GDSC2 2.5077 9.323 0.1853 25.0969
MDST8 GDSC1; GDSC2; CTRP2 2.6143 6.7002 2.1034 24.6459
SK-CO-1 GDSC2; CTRP2 2.6799 7.1701 2.0136 24.7687
NCI-H747 GDSC1; GDSC2; CTRP2 2.8833 7.1071 2.2555 23.2941
HCT 15 GDSC1; GDSC2; CTRP2 2.9726 8.2806 1.8972 24.3278
CaR-1 GDSC1; GDSC2 3.2009 11.3532 -0.1667 24.3826
SNU-C1 GDSC1; GDSC2; CTRP2 3.4263 7.5346 2.6768 20.1706
SNU-175 GDSC1; GDSC2 3.4394 12.1863 -0.368 24.4517
C2BBe1 GDSC1; GDSC2; CTRP2 3.5313 11.7552 0.8961 26.1655
LoVo GDSC1; GDSC2; CTRP2 3.557 7.5165 2.8227 19.2534
LS180 GDSC1; GDSC2; CTRP2 3.5686 8.8848 2.258 21.3534
NCI-H716 GDSC1; GDSC2; CTRP2 3.5789 7.6191 2.805 19.2593
LS513 GDSC1; GDSC2; CTRP2 3.5975 7.9372 2.6948 19.6264
COLO201 CTRP2 3.6224 7.1427 3.037 18.2589
T84 GDSC1; GDSC2; CTRP2 3.7352 9.6128 2.0989 21.5017
SW620 GDSC1; GDSC2; CTRP2 3.736 10.6622 1.6121 23.2534
SNU-407 GDSC1; GDSC2; CTRP2 3.7381 9.7446 2.0412 21.707
NCI-H508 GDSC2; CTRP2 3.7904 10.2962 1.8371 22.3135
LS1034 GDSC1; GDSC2; CTRP2 3.8415 9.1459 2.4184 20.0252
SW948 GDSC1; GDSC2; CTRP2 3.9227 8.2254 2.9105 17.9199
SNU-1033 CTRP2 4.2088 12.0606 1.3968 22.8038
SNU-1040 GDSC1; GDSC2 4.2168 17.5682 -2.389 30.315
KM12 GDSC1; GDSC2; CTRP2 4.3717 10.5221 2.2944 19.1603
COLO 320HSR GDSC1; GDSC2 4.3887 9.2068 1.9349 12.0372
LS123 GDSC1; GDSC2; CTRP2 4.3981 9.9227 2.6066 17.8946
SNU-283 GDSC2 4.4928 10.8243 0.4961 14.1618
DiFi GDSC2 4.5321 7.5037 2.133 4.1047
SNU-C2A CTRP2 4.5574 10.7814 2.3457 18.5182
GP2d CTRP2 4.618 14.61 0.5216 24.6317
OUMS-23 CTRP2 4.7093 9.3608 3.1748 14.8909
HT-55 GDSC1; GDSC2; CTRP2 4.7182 9.2278 3.2468 14.5794
SW1417 GDSC1; GDSC2; CTRP2 4.7653 11.5923 2.1436 18.7968
CL-11 GDSC1; GDSC2; CTRP2 4.8395 12.9438 1.5454 20.7973
HT115 GDSC1; GDSC2; CTRP2 4.8547 6.6389 4.5462 9.0508
HCC2998 GDSC1; GDSC2 4.9295 9.752 2.0951 10.0296
COLO205 GDSC1; GDSC2; CTRP2 5.0145 9.2735 3.5078 12.8224
COLO 320 CTRP2 5.1272 11.2219 2.6565 16.0012
HCT 116 GDSC1; GDSC2; CTRP2 5.1402 15.7453 0.4212 23.7564
GP5d GDSC1; GDSC2 5.1736 15.1418 -0.3957 20.3045
CCK-81 GDSC1; GDSC2; CTRP2 5.4616 11.1247 3.0036 13.8895
SNU-C5 GDSC1; GDSC2; CTRP2 5.8104 12.9583 2.3905 15.5867
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2 6.0199 10.0678 4.0123 8.5855
SNU-C2B GDSC1; GDSC2 6.0304 13.3894 1.1211 12.4047
CW-2 GDSC1; GDSC2; CTRP2 6.0702 10.5246 3.8257 9.268
LS411N GDSC1; GDSC2; CTRP2 6.1822 14.234 2.0639 16.0792
HCC-56 CTRP2 6.2075 7.6797 5.3583 2.5841
SNU-C4 CTRP2 6.5097 7.981 5.4311 1.8063
RKO GDSC1; GDSC2; CTRP2 6.5696 16.0791 1.4578 17.5038
COLO 678 GDSC1; GDSC2; CTRP2 6.6961 12.804 3.1911 10.727
SNU-61 GDSC1; GDSC2; CTRP2 6.7253 10.7491 4.2326 6.3956
DLD-1 CTRP2 6.9171 11.2523 4.1271 6.5187
SW1116 GDSC1; GDSC2; CTRP2 7.2083 17.5071 1.2518 17.0325
SNU-503 CTRP2 7.6724 16.0853 2.3077 12.5015
HT-29 GDSC1; GDSC2; CTRP2 12.1304 28.821 -0.7587 15.7073
HCT 8 CTRP2 15.1424 41.4993 -4.7944 20.6502
⏷ Show the Full List of 60 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 1.3277 6.4771 0.2895 28.6995
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 0.2129 6.8374 -0.5526 40.6273
SNU-886 CTRP2 0.3714 6.0709 -0.154 44.6344
SNU-878 CTRP2 0.5622 4.6772 0.3717 37.097
Huh-7 GDSC1; GDSC2 1.0185 7.8356 -0.6089 33.0082
Li-7 CTRP2 1.2035 4.3974 1.1031 32.582
SNU-423 GDSC1; GDSC2; CTRP2 1.7635 6.5186 1.2349 30.2873
SNU-761 CTRP2 2.1496 23.8893 -6.3007 41.3745
SNU-398 GDSC1; GDSC2; CTRP2 2.2588 9.4834 0.6474 30.5295
JHH-7 GDSC1; GDSC2 2.273 12.5008 -1.5794 31.5245
SNU-449 GDSC1; GDSC2; CTRP2 2.5088 5.6455 2.287 24.3191
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 3.4191 9.0813 2.0184 22.6422
PLC/PRF/5 CTRP2 3.5325 9.1289 2.1129 21.9888
JHH-2 GDSC1; GDSC2; CTRP2 3.8218 13.2963 0.4328 26.816
JHH-5 CTRP2 3.9759 11.8481 1.2791 23.7802
JHH-4 GDSC1; GDSC2; CTRP2 3.9762 8.1401 3.0027 17.4199
Hep-G2 CTRP2 4.2396 11.6102 1.6442 21.8697
HuH-6 CTRP2 4.3136 10.2909 2.3495 19.0924
SNU-475 GDSC1; CTRP2 4.5618 9.6934 2.8739 16.447
SK-HEP-1 GDSC1; GDSC2; CTRP2 4.7989 9.4006 3.2416 14.4086
HuH-1 GDSC1; GDSC2; CTRP2 5.2339 9.99 3.3612 12.9267
HLF CTRP2 5.2384 10.1097 3.3063 13.1411
JHH-1 GDSC1; GDSC2; CTRP2 5.5517 12.2857 2.5042 15.6818
Hep-G2/C3A GDSC1; GDSC2 5.6246 7.1521 3.7886 0.8081
JHH-6 GDSC1; GDSC2; CTRP2 6.992 7.704 5.8112 0.1129
HLE GDSC1; GDSC2 7.4345 9.0324 3.8128 0.0814
SNU-387 GDSC1; GDSC2; CTRP2 7.8094 18.8254 1.0586 16.6312
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 223 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SBC-3 GDSC1; GDSC2 -3.3161 -1.2638 -3.3167 62.114
IST-SL2 GDSC1; GDSC2 -3.1896 0.2636 -3.2158 67.1146
NCI-H64 GDSC1; GDSC2 -2.978 -0.9567 -2.9786 59.3813
SBC-1 GDSC1; GDSC2 -2.92 -0.5575 -2.9225 65.7543
NCI-H748 GDSC1; GDSC2 -2.1092 3.7418 -2.547 56.6646
NCI-H1876 GDSC1; GDSC2 -1.6717 2.1797 -1.7828 48.8514
NCI-H847 GDSC1; GDSC2 -1.2555 4.5961 -1.842 46.2325
NCI-H2869 GDSC1; GDSC2 -1.0786 4.74 -1.6911 49.42
NCI-H290 GDSC1; GDSC2 -0.7969 9.6096 -3.2502 48.2698
NCI-H1648 GDSC1; GDSC2 -0.5613 5.2336 -1.2814 41.6148
NCI-H1048 GDSC1; GDSC2 -0.5454 3.0661 -0.7073 40.1428
NCI-H1581 GDSC1; GDSC2; CTRP2 -0.4844 6.2312 -1.1325 44.5373
IST-SL1 GDSC1; GDSC2 -0.4768 7.0092 -1.8333 45.851
Ms-1 GDSC1; GDSC2 -0.402 4.478 -0.8768 39.8916
UMC-11 GDSC1; GDSC2 -0.3194 4.2894 -0.7344 39.1062
COR-L303 GDSC1; GDSC2 -0.2482 6.5771 -1.4222 44.1327
NCI-H520 GDSC1; GDSC2; CTRP2 -0.1112 4.8186 -0.3829 41.6558
COR-L311 GDSC1; GDSC2 -0.0934 5.4745 -0.8542 38.3596
Calu-3 GDSC1; GDSC2; CTRP2 0.2135 7.554 -0.787 41.0451
NCI-H1437 GDSC1; GDSC2 0.5592 5.2947 -0.086 36.7941
Lu-99 CTRP2 0.7873 5.9081 0.3439 36.3361
NCI-H1184 CTRP2 0.8973 5.4826 0.57 35.3009
NCI-H358 GDSC1; GDSC2; CTRP2 0.8993 5.9605 0.4521 35.6289
NCI-H1836 GDSC1; GDSC2 0.9041 6.335 -0.101 35.1769
DMS 273 GDSC1; GDSC2; CTRP2 0.9063 7.577 -0.0454 36.8801
NCI-H211 GDSC1; GDSC2; CTRP2 0.9871 7.8601 -0.0589 36.6189
NCI-H209 GDSC1; GDSC2 1.0751 3.2955 0.9969 26.7485
EMC-BAC-2 GDSC1; GDSC2 1.1023 8.3336 -0.743 33.1004
CPC-N GDSC1; GDSC2 1.1065 9.1243 -1.0959 34.0896
COR-L279 GDSC2 1.1096 5.5546 -0.5648 18.8
NCI-H1666 GDSC1; GDSC2; CTRP2 1.1182 9.8125 -0.6816 37.5051
EPLC-272H GDSC1; GDSC2; CTRP2 1.1221 8.5914 -0.1878 36.4382
LC-2/ad GDSC1; GDSC2 1.1262 8.6165 -0.8457 36.3887
PaCa-3 GDSC1; GDSC2 1.1507 8.5921 -0.8099 33.1197
NCI-H2171 GDSC1; GDSC2 1.1773 6.8224 -0.0111 33.6285
NCI-H250 GDSC2 1.1808 8.5451 -1.2347 32.6342
NCI-H1975 GDSC1; GDSC2; CTRP2 1.1939 4.9797 0.999 32.9508
NCI-H1341 GDSC2; CTRP2 1.3055 4.4043 1.2108 31.8855
HCC44 GDSC1; GDSC2; CTRP2 1.3918 7.5348 0.494 33.7732
Lu-139 GDSC1; GDSC2 1.4017 6.6506 0.2953 28.4043
NCI-H2795 GDSC1; GDSC2 1.4655 9.6126 -0.9642 32.4433
COR-L321 GDSC1; GDSC2 1.4974 8.4092 -0.3775 33.4848
NCI-H2135 GDSC1; GDSC2 1.5959 7.3109 0.2139 31.0123
NCI-H2227 GDSC1; GDSC2 1.6281 13.6863 -2.7589 38.4522
NCI-H510A GDSC1; GDSC2 1.6381 10.9205 -1.4142 35.7793
COR-L105 GDSC1; GDSC2; CTRP2 1.6414 5.949 1.265 30.5893
DMS 114 GDSC1; GDSC2; CTRP2 1.7737 6.5076 1.2494 30.2065
SK-LU-1 GDSC1; GDSC2; CTRP2 1.8565 11.871 -0.8173 35.393
SK-MES-1 GDSC1; GDSC2; CTRP2 1.8843 6.6202 1.335 29.568
NCI-H3122 GDSC1; GDSC2 1.9342 9.1898 -0.3056 28.7559
NCI-H1734 GDSC1; GDSC2; CTRP2 1.9361 6.1513 1.5313 28.746
NCI-H1793 GDSC1; GDSC2; CTRP2 1.9967 9.7765 0.2503 32.4504
NCI-H2196 GDSC1; GDSC2; CTRP2 2.0304 6.8054 1.4347 28.7702
NCI-H2085 GDSC1; GDSC2; CTRP2 2.0327 7.5365 1.1842 29.5854
NCI-H1568 GDSC1; GDSC2; CTRP2 2.0744 8.0436 1.0391 29.9156
BEN GDSC1; GDSC2; CTRP2 2.0977 13.58 -1.3649 35.7467
EBC-1 GDSC1; GDSC2; CTRP2 2.1365 6.5245 1.6395 27.7422
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 2.1951 7.4756 1.3811 28.4315
SW1271 GDSC1; GDSC2; CTRP2 2.2429 12.6634 -0.7943 34.1945
NCI-H1944 GDSC1; GDSC2; CTRP2 2.252 7.2067 1.5387 27.7254
NCI-H2373 GDSC1; GDSC2 2.2546 10.3902 -0.5699 28.6105
NCI-H1155 GDSC1; GDSC2; CTRP2 2.2832 6.1327 1.9153 26.3285
ABC-1 GDSC1; GDSC2 2.3402 9.8095 -0.2085 29.6927
NCI-H2228 GDSC1; GDSC2; CTRP2 2.3652 11.3388 -0.0635 32.1405
COLO 699 CTRP2 2.3851 7.8733 1.4361 27.6626
NCI-H1693 GDSC1; GDSC2; CTRP2 2.4319 9.7125 0.7281 29.7672
NCI-H1304 GDSC1 2.4336 18.8187 -4.5546 43.1285
NCI-H2066 GDSC2 2.4438 9.4605 -1.3671 18.8554
HCC33 GDSC1; GDSC2 2.4613 11.0379 -0.6897 30.8635
NCI-H1703 GDSC1; GDSC2; CTRP2 2.4682 8.9053 1.1096 28.4808
NCI-H292 GDSC1; GDSC2; CTRP2 2.4819 9.8794 0.7069 29.6808
NCI-H146 GDSC2; CTRP2 2.488 8.0035 1.4954 27.151
LCLC-97TM1 GDSC1; GDSC2; CTRP2 2.509 10.6519 0.3921 30.5068
COR-L32 GDSC2 2.56 6.3784 1.12 16.2399
NCI-H1355 GDSC1; GDSC2; CTRP2 2.5784 10.9037 0.3486 30.4242
LXF 289 GDSC1; GDSC2; CTRP2 2.594 7.5915 1.7666 25.8989
NCI-H2731 GDSC1; GDSC2 2.621 10.5795 -0.3171 26.616
NCI-H647 GDSC1; GDSC2; CTRP2 2.6755 7.6042 1.8491 25.366
NCI-H810 GDSC1; GDSC2; CTRP2 2.7043 8.8423 1.3827 26.8873
NCI-H69 GDSC1; GDSC2; CTRP2 2.7201 8.7148 1.4526 26.606
DV-90 CTRP2 2.7304 6.3576 2.3376 23.4551
LK-2 GDSC1; GDSC2 2.7394 10.2699 -0.0556 25.3096
NCI-H661 GDSC1; GDSC2; CTRP2 2.8689 9.7475 1.1615 27.1386
COR-L23 GDSC1; GDSC2 2.8703 6.7877 1.7391 17.1024
IA-LM GDSC1; GDSC2; CTRP2 2.9201 11.2762 0.5203 28.9599
NCI-H446 GDSC1; GDSC2; CTRP2 2.9625 10.763 0.7987 28.014
HCC827 GDSC1; GDSC2; CTRP2 2.9983 7.1254 2.3729 22.528
NCI-H650 GDSC1; GDSC2; CTRP2 3.0286 9.1422 1.5908 25.246
NCI-H2141 GDSC1; GDSC2 3.0678 12.6458 -0.9264 27.3439
EMC-BAC-1 GDSC1; GDSC2 3.0695 9.3998 0.6762 23.6518
NCI-H2087 GDSC1; GDSC2; CTRP2 3.0781 11.1558 0.7329 27.8909
NCI-H1623 GDSC1; GDSC2; CTRP2 3.0805 8.6817 1.8424 24.2161
NCI-H2347 GDSC1; GDSC2 3.0833 13.3801 -1.2767 28.3602
HCC4006 CTRP2 3.1197 9.8268 1.3815 25.7038
NCI-H841 GDSC1; GDSC2; CTRP2 3.2047 9.2054 1.7442 24.2164
PC-14 GDSC1; GDSC2; CTRP2 3.2431 7.4009 2.5334 21.2272
NCI-H345 GDSC1; GDSC2 3.2482 9.8007 0.6432 23.2174
HOP-62 GDSC1; GDSC2; CTRP2 3.2773 8.8778 1.9619 23.237
CAL-12T GDSC1; GDSC2; CTRP2 3.3455 11.2476 0.9542 26.4775
RERF-LC-Ad2 CTRP2 3.3813 8.9108 2.0546 22.6133
NCI-H2030 GDSC1; GDSC2; CTRP2 3.4073 12.772 0.2915 28.2875
LC-1/sq GDSC1; GDSC2 3.409 10.3942 0.495 21.2023
NCI-H1436 GDSC1; GDSC2 3.5341 9.8732 0.8652 21.3128
NCI-H187 GDSC1 3.5585 10.3035 0.6733 28.194
NCI-H2804 GDSC1; GDSC2 3.5838 11.4022 0.1493 24.2512
Lu-134-A GDSC1; GDSC2 3.5973 12.6531 -0.4619 26.4934
NCI-H82 GDSC1; GDSC2 3.6145 8.9176 1.4109 16.5429
NCI-H835 GDSC2 3.6163 6.7766 0.7864 4.0578
NCI-H2023 GDSC1; GDSC2; CTRP2 3.6467 7.698 2.8447 18.9204
HCC78 GDSC1; GDSC2; CTRP2 3.7016 10.1722 1.8073 22.6519
Lu-65 GDSC1; GDSC2; CTRP2 3.7057 9.5536 2.0964 21.5888
HCC1588 CTRP2 3.7463 9.0196 2.3791 20.4245
LK2 CTRP2 3.7729 6.6689 3.3706 16.5745
NCI-H2405 GDSC1; GDSC2; CTRP2 3.7982 10.873 1.5736 23.2267
COR-L51 CTRP2 3.8519 7.9156 2.9697 17.8805
Calu-6 GDSC1; GDSC2; CTRP2 3.8534 9.0782 2.4611 19.8318
NCI-H23 GDSC1; GDSC2; CTRP2 3.8974 8.159 2.9131 17.9772
NCI-H2803 GDSC1; GDSC2 3.9583 12.4653 -0.0566 23.9584
NCI-H2081 GDSC1; GDSC2; CTRP2 3.9642 8.9398 2.6355 18.8748
NCI-H1395 CTRP2 3.9685 7.8921 3.1011 17.0583
NCI-H1435 GDSC1; GDSC2; CTRP2 3.9827 9.5894 2.3563 19.8958
RERF-LC-MS GDSC1; GDSC2; CTRP2 4.0106 9.3287 2.5044 19.2594
NCI-H1563 GDSC1; GDSC2; CTRP2 4.0218 11.9229 1.2866 23.6397
NCI-H2591 GDSC1; GDSC2 4.033 10.2709 1.1034 16.886
RERF-LC-Sq1 GDSC1; GDSC2 4.0334 10.2382 1.1201 16.8086
NCI-H3255 GDSC1; GDSC2 4.057 11.6211 0.4493 21.6208
NCI-H526 GDSC1; GDSC2; CTRP2 4.0598 9.293 2.5699 18.8817
NCI-H1339 CTRP2 4.0629 9.8377 2.3198 19.8301
NCI-H2286 CTRP2 4.0713 9.9877 2.2577 20.0439
NCI-H740 GDSC2 4.081 9.4106 0.8848 13.069
NCI-H524 GDSC1; GDSC2 4.0912 14.1558 -0.7886 24.202
NCI-H2810 GDSC2 4.0975 7.597 1.7912 7.6374
LB647-SCLC GDSC2 4.0996 7.4553 1.8621 7.199
NCI-H226 GDSC1; GDSC2; CTRP2 4.1033 11.9501 1.3507 23.2209
NCI-H1963 GDSC2 4.1416 6.3131 1.2599 1.0754
DMS 454 CTRP2 4.1468 9.5554 2.5344 18.798
NCI-H838 GDSC1; GDSC2; CTRP2 4.1659 9.565 2.5487 18.6947
NCI-H2110 GDSC1; GDSC2; CTRP2 4.1903 10.3405 2.2068 19.9376
HCC15 GDSC1; GDSC2; CTRP2 4.2077 10.4545 2.1693 20.0349
HCC1833 CTRP2 4.2389 10.4897 2.1826 19.9081
HCC2935 CTRP2 4.2574 8.6609 3.0574 16.474
NCI-H1694 GDSC1; GDSC2; CTRP2 4.2687 8.3138 3.2255 15.7813
NCI-H1993 GDSC1; GDSC2 4.2835 13.1572 -0.1278 21.3934
NCI-H2595 GDSC1; GDSC2 4.3025 11.2143 0.8595 17.3119
Lu-165 GDSC1; GDSC2 4.3163 10.3142 1.3211 15.177
HCC2108 CTRP2 4.3257 11.4722 1.7923 21.1313
HCC95 CTRP2 4.3285 11.8746 1.5996 21.8099
NCI-H2106 CTRP2 4.3372 12.4719 1.3166 22.7637
DMS 79 GDSC1; GDSC2; CTRP2 4.3538 10.7637 2.1613 19.7064
DMS 53 GDSC1; GDSC2; CTRP2 4.3558 8.2409 3.3466 15.0783
NCI-H322 CTRP2 4.3668 8.0693 3.4344 14.7022
Lu-135 GDSC1; GDSC2 4.3889 10.7098 1.1836 15.6405
T3M-10 CTRP2 4.4047 9.0887 3.0065 16.3048
NCI-H2170 GDSC1; GDSC2; CTRP2 4.422 7.2875 3.8284 13.0087
NCI-H1755 GDSC1; GDSC2; CTRP2 4.4272 11.2184 2.011 20.0883
LC-1/sq-SF CTRP2 4.4732 9.7481 2.7623 17.1021
RERF-LC-KJ GDSC1; GDSC2 4.5415 8.1111 2.6071 8.2957
COR-L88 GDSC1; GDSC2; CTRP2 4.5488 12.5569 1.4709 21.7317
NCI-H2444 GDSC1; GDSC2; CTRP2 4.558 8.0594 3.633 13.4226
NCI-H1915 GDSC1; GDSC2; CTRP2 4.6016 11.0553 2.2542 18.7621
COLO 668 GDSC1; GDSC2; CTRP2 4.6036 11.0113 2.2775 18.6687
A-549 GDSC1; GDSC2; CTRP2 4.6225 7.4661 3.9614 11.953
NCI-H1573 GDSC1; GDSC2; CTRP2 4.6456 10.2329 2.6946 16.955
NCI-H889 CTRP2 4.658 13.7722 0.972 23.1409
COR-L95 GDSC1; GDSC2; CTRP2 4.7387 11.1732 2.3245 18.1731
A-427 GDSC1; GDSC2 4.7941 9.8087 1.9614 12.2468
NCI-H1792 GDSC1; GDSC2; CTRP2 4.8127 10.6927 2.628 16.8254
NCI-H2122 GDSC1; GDSC2; CTRP2 4.8151 7.8911 3.9682 11.4308
SHP-77 GDSC1; GDSC2; CTRP2 4.8158 8.1782 3.8367 11.9583
VMRC-LCD GDSC2; CTRP2 4.8459 10.1087 2.9437 15.4972
NCI-H1105 GDSC2; CTRP2 4.8951 10.9077 2.5992 16.7492
NCI-H2009 GDSC1; GDSC2; CTRP2 4.9294 10.7324 2.7168 16.2082
EKVX GDSC1; GDSC2; CTRP2 4.9573 10.4334 2.889 15.4601
RERF-LC-A1 CTRP2 5.0157 14.2317 1.0647 22.026
NCI-H1650 GDSC1; GDSC2; CTRP2 5.0336 11.4417 2.4631 16.966
MOR/CPR CTRP2 5.0444 7.1512 4.5329 8.5906
Lu-99A GDSC1; GDSC2 5.0594 12.7276 0.7167 16.1732
NCI-H2722 GDSC1; GDSC2 5.0826 15.3123 -0.5529 21.0638
NCI-H522 GDSC1; GDSC2; CTRP2 5.1008 11.9197 2.2876 17.4911
HCC2279 CTRP2 5.1411 11.7024 2.4314 16.8493
NCI-H727 GDSC1; GDSC2; CTRP2 5.1578 13.0286 1.7885 19.2189
ChaGo-K-1 GDSC1; GDSC2; CTRP2 5.1595 12.7803 1.9133 18.7614
NCI-H1092 GDSC1; GDSC2; CTRP2 5.1708 11.6359 2.4909 16.5528
NCI-H1869 GDSC1; GDSC2; CTRP2 5.1807 15.3408 0.6582 22.9519
LUDLU-1 CTRP2 5.2168 9.0183 3.8218 11.0696
NCI-H1299 GDSC1; GDSC2; CTRP2 5.2344 12.1451 2.2952 17.1674
NCI-H1385 CTRP2 5.25 8.1753 4.2614 9.1829
NCI-H1838 GDSC1; GDSC2; CTRP2 5.2573 9.0584 3.84 10.903
NCI-H2291 GDSC1; GDSC2; CTRP2 5.2831 13.8041 1.5132 19.9213
HCC366 GDSC2; CTRP2 5.4003 8.9431 4.0286 9.8026
COR-L47 CTRP2 5.4239 9.2741 3.8872 10.3374
NCI-H1373 CTRP2 5.5268 11.5278 2.8603 14.3277
HOP-92 GDSC1; GDSC2; CTRP2 5.5446 11.2962 2.9912 13.7642
NCI-H2029 GDSC1; GDSC2; CTRP2 5.5884 11.3018 3.0266 13.5293
NCI-H196 GDSC1; GDSC2; CTRP2 5.603 11.7629 2.8094 14.3712
LOU-NH91 GDSC1; GDSC2; CTRP2 5.685 9.129 4.1932 8.5032
SW1573 GDSC1; GDSC2 5.6923 13.0666 1.0324 13.4595
HCC1438 CTRP2 5.8128 10.6149 3.5634 10.8673
NCI-H2172 GDSC1; GDSC2; CTRP2 6.0081 13.1735 2.4495 14.9615
NCI-H460 GDSC1; GDSC2; CTRP2 6.0376 10.315 3.9034 9.0067
NCI-H1781 GDSC1; GDSC2 6.1275 7.621 3.8273 0.3753
NCI-H2126 CTRP2 6.3868 10.405 4.1425 7.3549
NCI-H720 GDSC1; GDSC2 6.3942 7.667 3.9124 0.13
RERF-LC-Ad1 CTRP2 6.4022 10.6941 4.0106 7.8778
NCI-H1688 GDSC1; GDSC2 6.4396 15.1921 0.5346 14.1265
NCI-H2461 GDSC1; GDSC2 6.4401 18.4632 -1.0704 19.9865
HCC1171 CTRP2 6.509 13.8738 2.5098 13.7645
NCI-H1651 GDSC1; GDSC2; CTRP2 6.623 11.1559 3.9534 7.7267
NCI-H1770 GDSC1; GDSC2 6.6239 11.4589 2.4406 5.9937
Sq-1 CTRP2 6.7656 10.7951 4.24 6.2988
SBC-5 GDSC1; GDSC2; CTRP2 6.7703 15.9833 1.6662 16.4018
NCI-H441 GDSC1; GDSC2; CTRP2 7.0933 10.7484 4.4988 4.7288
NCI-H322M GDSC1; GDSC2 7.2114 16.9328 0.2318 13.9404
NCI-H2369 GDSC1; GDSC2 7.3363 15.8618 0.8295 11.341
KNS-62 GDSC2; CTRP2 7.3526 20.1644 0.0428 20.5162
NCI-H2818 GDSC1; GDSC2 7.417 14.9849 1.2963 9.2543
HCC1195 CTRP2 7.6298 26.0593 -2.6745 26.4641
NCI-H596 GDSC1; GDSC2 7.818 23.0475 -2.3113 21.1411
Calu-1 CTRP2 8.3 13.7275 3.8805 5.5369
NCI-H513 GDSC1; GDSC2 8.3264 18.8332 0.0706 12.7276
NCI-H2342 GDSC1; GDSC2; CTRP2 8.6714 20.5072 0.8683 15.8475
LCLC-103H GDSC1; GDSC2; CTRP2 12.5731 24.7613 1.4044 9.1752
Hs 888.Lu CTRP2 2.456 9.0994 1.0153 28.8162
⏷ Show the Full List of 223 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 -0.6599 3.9105 -1.0083 41.5252
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.2094 10.4059 0.1963 31.9364
A2780 GDSC1; GDSC2; CTRP2 0.0992 6.0013 -0.4321 40.8626
TOV-112D GDSC1; GDSC2; CTRP2 0.9268 7.3201 0.0655 36.5382
MCAS CTRP2 1.0161 6.8625 0.3134 35.5824
SNU-8 CTRP2 1.414 6.4584 0.8723 32.5936
JHOS-4 GDSC2 1.7791 5.5382 0.7624 21.2062
OVK18 GDSC1; GDSC2; CTRP2 2.1583 7.7369 1.2452 28.9931
ONCO-DG-1 CTRP2 2.2215 12.2867 -0.6414 33.9264
IGROV-1 GDSC1; GDSC2; CTRP2 2.4435 7.5833 1.6084 26.9002
OAW42 GDSC1; GDSC2; CTRP2 2.5223 11.2598 0.1304 31.1782
Caov-3 GDSC1; GDSC2; CTRP2 2.5403 9.8648 0.7733 29.3088
COV434 CTRP2 2.606 7.1346 1.9465 25.2289
ES-2 GDSC1; GDSC2 2.8362 6.9132 1.6472 17.6482
EFO-27 GDSC1; GDSC2; CTRP2 2.847 8.0111 1.8736 24.7747
OVSAHO CTRP2 3.0596 10.0019 1.242 26.3355
OVTOKO GDSC1; GDSC2; CTRP2 3.1518 10.3695 1.1683 26.3201
OVCAR-4 GDSC1; GDSC2; CTRP2 3.1566 8.0098 2.2014 22.7014
JHOM-1 CTRP2 3.1619 9.3255 1.6476 24.6745
SNU-840 CTRP2 3.2292 12.414 0.2904 28.7641
OAW28 GDSC1; GDSC2; CTRP2 3.3569 10.1 1.4971 24.6586
DOV13 GDSC1; GDSC2; CTRP2 3.4667 7.6737 2.6644 20.1041
SNU-119 CTRP2 3.5318 8.3608 2.4478 20.7413
JHOS-2 GDSC1; GDSC2; CTRP2 3.5961 9.2451 2.1257 21.7711
RMG-I GDSC1; GDSC2; CTRP2 3.6237 13.1741 0.3048 27.6873
TYK-nu GDSC1; GDSC2; CTRP2 3.7773 9.8169 2.047 21.5833
Caov-4 GDSC1; GDSC2 3.7942 12.5541 -0.2418 23.0532
COV644 CTRP2 3.8582 8.6342 2.6649 19.039
OV-90 GDSC1; GDSC2; CTRP2 3.9037 10.5873 1.8114 22.1144
OV7 CTRP2 3.9465 10.1509 2.0586 21.104
HEY A8 CTRP2 4.0028 12.1495 1.1592 24.1104
SK-OV-3 GDSC1; GDSC2; CTRP2 4.2561 10.1374 2.367 19.1675
OC 314 GDSC1; GDSC2; CTRP2 4.3193 9.7285 2.6222 18.0272
EFO-21 GDSC1; GDSC2; CTRP2 4.6867 10.9616 2.3793 18.0841
COV362 CTRP2 4.8739 10.6669 2.6974 16.4116
FU-OV-1 GDSC1; GDSC2; CTRP2 4.9482 14.6554 0.7944 23.0433
OVCAR-8 GDSC1; GDSC2; CTRP2 5.1448 10.4741 3.0415 14.4252
OVCAR-5 GDSC1; GDSC2; CTRP2 5.2424 14.3442 1.2086 21.0499
OV56 GDSC1; GDSC2; CTRP2 5.3046 8.5039 4.1544 9.4971
Kuramochi GDSC1; GDSC2; CTRP2 5.4699 13.3089 1.923 18.0535
JHOC-5 CTRP2 5.5847 9.4376 3.951 9.7259
ES2 CTRP2 5.7701 10.9871 3.3409 11.8727
OVKATE GDSC1; GDSC2 5.8431 14.0424 0.6638 14.7463
OVCAR-3 GDSC1; GDSC2 5.961 10.1802 2.6203 5.5335
TOV-21G GDSC1; GDSC2 6.6039 17.1779 -0.3177 17.1
OVISE GDSC1; GDSC2; CTRP2 8.483 21.5211 0.2324 18.0719
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 2.2124 9.4065 0.6318 30.7174
Yamato-SS CTRP2 2.6753 12.888 -0.4734 32.245
EW-8 GDSC1; GDSC2 -2.3263 0.2955 -2.3353 54.0589
Hs 633.T GDSC1; GDSC2 -0.1237 3.0231 -0.2468 36.6447
A-204 GDSC1; GDSC2; CTRP2 1.5997 8.3633 0.4095 33.3044
Rh30 GDSC1; GDSC2 1.6664 7.6637 0.1297 28.0923
KYM-1 GDSC1; GDSC2; CTRP2 1.8179 8.6253 0.5387 32.2295
Rh41 GDSC1; GDSC2; CTRP2 1.8627 7.5114 1.0102 30.6813
G-402 GDSC1; GDSC2; CTRP2 2.026 9.4201 0.4318 31.8653
VA-ES-BJ GDSC1; GDSC2 2.1563 7.2218 0.8247 23.585
SK-LMS-1 GDSC1; GDSC2; CTRP2 2.2491 7.6704 1.3674 28.3095
G-401 GDSC1; GDSC2; CTRP2 2.4369 10.8197 0.2436 31.1272
MFH-ino GDSC1; GDSC2 2.6585 11.4875 -0.7267 27.8872
TE 441.T GDSC1; GDSC2; CTRP2 2.6813 9.3879 1.126 27.7961
TTC-709 CTRP2 2.7556 9.2014 1.2832 27.0679
Tm87-16 CTRP2 3.0052 8.7166 1.7492 24.7595
RKN GDSC1; GDSC2; CTRP2 3.1911 8.5076 2.0313 23.2255
STS-0421 GDSC2 3.3097 7.0887 1.4283 11.972
TE 617.T CTRP2 3.4817 6.7162 3.0391 18.6555
SW982 GDSC1; GDSC2; CTRP2 3.5176 10.9458 1.2648 25.0118
RD GDSC1; GDSC2; CTRP2 3.6921 8.4559 2.5727 19.8338
Rh18 CTRP2 3.7365 10.6668 1.6105 23.2575
HT-1080 GDSC1; GDSC2; CTRP2 3.813 9.4287 2.261 20.6944
SW872 GDSC1; GDSC2 3.8593 8.466 1.8527 13.7536
MES-SA GDSC1; GDSC2 4.5162 11.7624 0.7623 17.2227
Hs 729.T CTRP2 4.8307 9.4362 3.2548 14.28
BT-16 CTRP2 5.1655 8.7495 3.9042 10.8476
SK-UT-1 GDSC1; GDSC2; CTRP2 5.2232 11.3137 2.6975 15.6276
GCT GDSC1; GDSC2; CTRP2 5.346 10.9513 2.9872 14.2032
BT-12 CTRP2 7.0933 8.1673 5.6778 0.3602
SW684 GDSC1; GDSC2 7.6971 18.9583 -0.4102 15.4807
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 3.8217 7.1521 3.2465 16.9023
SYO-1 CTRP2 3.9637 13.5512 0.4418 26.435
P-STS CTRP2 4.698 8.1701 3.7232 12.7083
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.0747 9.9463 2.2805 19.9489
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC1; GDSC2; CTRP2 2.9537 10.1465 1.0697 27.1924
MSTO-211H GDSC1; GDSC2; CTRP2 2.9818 8.3027 1.8977 24.3
NCI-H28 GDSC1; GDSC2; CTRP2 3.6647 7.2132 3.0555 18.0691
MPP 89 GDSC1; GDSC2; CTRP2 3.857 10.3703 1.8679 22.0306
JL-1 CTRP2 4.5194 9.4023 2.9713 16.1627
NCI-H2052 GDSC1; GDSC2; CTRP2 4.5458 9.158 3.1126 15.5352
ACC-MESO-1 CTRP2 4.8552 12.5038 1.777 19.9395
IST-Mes1 GDSC1; GDSC2; CTRP2 4.9093 15.0821 0.5479 23.8891
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1; GDSC2 1.1503 7.6528 -0.3936 31.8236
22Rv1 GDSC1; GDSC2; CTRP2 1.2331 5.7818 0.863 33.242
LNCaP clone FGC GDSC1; GDSC2; CTRP2 2.1741 4.8082 2.0827 26.0941
PaCa-3 CTRP2 3.4507 9.2573 1.9725 22.7234
NCI-H660 GDSC2 4.8145 6.0447 2.9147 0.3777
DU145 GDSC1; GDSC2; CTRP2 4.8641 11.0771 2.4875 17.2556
VCaP GDSC1; GDSC2; CTRP2 5.5124 13.3442 1.9422 17.8926
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 2.0612 7.2477 0.7168 24.3662
YD-15 CTRP2 3.3442 9.7851 1.6274 24.2426
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -2.2703 2.4912 -2.4679 58.5751
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC1; GDSC2; CTRP2 -0.0447 5.7495 -0.5226 41.6439
GCIY GDSC1; GDSC2 0.0985 6.1799 -0.9008 37.6139
NCC-StC-K140 CTRP2 0.4345 6.6772 -0.2617 39.1547
RF-48 GDSC1; GDSC2 0.7224 7.2426 -0.6623 34.3223
ECC10 GDSC1; GDSC2; CTRP2 0.9333 6.67 0.2839 35.9602
Fu97 GDSC1; GDSC2; CTRP2 1.1014 7.406 0.2251 35.508
GSS CTRP2 1.3336 4.985 1.149 31.9935
SNU-16 GDSC1; GDSC2; CTRP2 1.7986 3.745 1.7841 28.3345
SNU-5 GDSC1; GDSC2; CTRP2 1.8503 6.1036 1.451 29.2922
Hs 746.T GDSC1; GDSC2; CTRP2 1.8595 7.6728 0.9481 30.8844
SNU-1 GDSC1; GDSC2; CTRP2 2.0494 8.1439 0.9738 30.1982
SNU-668 CTRP2 2.3204 9.7913 0.5789 30.5408
HSC-39 GDSC1; GDSC2 2.3414 8.5944 0.3727 24.8775
23132/87 GDSC1; GDSC2; CTRP2 2.9182 8.6264 1.6966 25.193
RERF-GC-1B GDSC1; GDSC2 3.1226 13.1457 -1.1254 27.8038
SNU-620 CTRP2 3.1619 6.8837 2.6351 21.0854
SNU-216 CTRP2 3.3506 9.2453 1.8759 23.3452
NUGC-3 GDSC1; GDSC2; CTRP2 3.4067 8.4205 2.2925 21.6661
NCI-N87 GDSC1; GDSC2; CTRP2 3.7721 7.6501 2.9964 17.9952
IM95 GDSC1; GDSC2; CTRP2 3.8579 8.7093 2.6312 19.169
MKN1 GDSC1; GDSC2; CTRP2 4.1555 9.1309 2.74 17.9784
TGBC11TKB GDSC1; GDSC2 4.5653 5.9856 3.6832 2.7486
LMSU CTRP2 4.5785 11.6614 1.937 20.0001
OCUM-1 GDSC1; GDSC2 4.599 13.4456 -0.0111 20.19
KE-39 CTRP2 4.7656 10.2163 2.816 16.1931
ECC12 GDSC2; CTRP2 5.002 9.5732 3.3505 13.4934
MKN7 GDSC1; GDSC2; CTRP2 5.0446 11.2133 2.5858 16.4633
SK-GT-2 GDSC2 5.1296 7.3121 1.2905 0.4179
SNU-719 CTRP2 5.1883 10.259 3.1871 13.7382
MKN74 CTRP2 5.34 14.5661 1.1832 20.9226
TMK-1 GDSC1; GDSC2 5.3851 17.5719 -1.4392 24.9694
SCH GDSC1; GDSC2 5.5659 11.2037 1.8546 11.0286
HuG1-N CTRP2 5.5954 18.7573 -0.69 25.8212
KATO III GDSC2; CTRP2 5.6739 10.1926 3.654 10.7752
SNU-601 CTRP2 5.8944 11.4346 3.2233 12.1044
NUGC-4 GDSC1; GDSC2; CTRP2 5.9438 13.6548 2.155 16.212
MKN45 GDSC1; GDSC2; CTRP2 6.1209 20.9413 -1.3404 26.3335
GSU CTRP2 6.2625 6.9405 5.7625 0.8242
SH-10-TC CTRP2 6.4071 10.8361 3.9437 8.1478
MKN28 GDSC1; GDSC2 6.7683 13.556 1.5499 9.1812
AGS GDSC1; GDSC2; CTRP2 7.9197 18.7676 1.17 16.083
SNG-M GDSC1; GDSC2; CTRP2 3.4724 7.9503 2.5581 20.4891
SNU-685 CTRP2 5.0882 11.4052 2.5306 16.5814
SNU-1077 CTRP2 5.5117 11.4094 2.906 14.1761
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1; GDSC2 -1.3189 6.642 -2.5934 50.9226
K5 GDSC1; GDSC2 -0.6509 4.8437 -1.2561 42.0198
IHH-4 GDSC1; GDSC2 0.0883 7.5191 -1.4414 38.9457
8305C GDSC1; GDSC2; CTRP2 2.0432 7.8945 1.0626 29.9398
HTC-C3 GDSC1; GDSC2 2.356 7.1982 1.0368 21.9949
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 2.8254 13.6332 -0.6802 32.3075
CAL-62 GDSC1; GDSC2; CTRP2 2.894 9.1657 1.4417 26.1392
SW579 CTRP2 2.907 8.2442 1.843 24.7095
CGTH-W-1 GDSC1; GDSC2; CTRP2 3.6124 10.6032 1.5184 23.9024
BHT-101 GDSC1; GDSC2; CTRP2 3.6412 10.2662 1.7038 23.1788
TT2609-C02 GDSC1; GDSC2; CTRP2 3.7344 8.9987 2.3764 20.4665
B-CPAP GDSC1; GDSC2; CTRP2 3.7889 12.8625 0.6119 26.3707
8505C GDSC1; GDSC2; CTRP2 3.8542 12.9312 0.6404 26.1197
FTC-238 CTRP2 4.2298 7.0994 3.7016 14.0247
ASH-3 GDSC1; GDSC2 4.74 8.9049 2.3688 9.0668
TT GDSC1; GDSC2; CTRP2 5.1837 10.734 2.9487 14.7129
FTC-133 GDSC1; GDSC2; CTRP2 5.3337 10.783 3.0595 13.9376
WRO GDSC1; GDSC2 8.9252 18.0315 0.8175 9.034
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-04B GDSC1; GDSC2 -0.5764 13.3386 -4.7169 47.8292
JHU-011 GDSC1; GDSC2 0.1057 7.5857 -1.4507 42.3466
PCI-06A GDSC1; GDSC2 0.4071 7.8996 -1.2684 40.5677
YD-10B CTRP2 0.5693 5.5954 0.1856 37.5736
SCC-15 GDSC1; GDSC2 1.302 13.6427 -3.0446 37.5755
SCC-25 GDSC1; GDSC2; CTRP2 1.465 7.1358 0.7112 32.9026
BB30-HNC GDSC1; GDSC2 1.6029 8.2853 -0.215 32.5233
HO-1-u-1 GDSC1; GDSC2 2.0023 13.3635 -2.2525 33.9425
SNU-899 CTRP2 2.133 7.0695 1.4576 28.3701
SAS GDSC1; GDSC2 2.1993 12.3546 -1.5764 31.7384
PCI-15A GDSC1; GDSC2 2.5791 9.0779 0.3713 26.6305
SNU-1076 CTRP2 2.8443 8.3545 1.7319 25.2825
Ca9-22 GDSC1; GDSC2 2.8493 11.0931 -0.3575 26.0785
HSC-4 GDSC1; GDSC2; CTRP2 2.8771 7.994 1.9123 24.5496
CAL-33 GDSC1; GDSC2; CTRP2 2.9664 8.6125 1.7527 24.8578
BHY GDSC1; GDSC2; CTRP2 2.9694 9.1037 1.5464 25.5666
NCI-H3118 GDSC1; GDSC2 3.3717 9.8775 0.7173 20.361
JHU-029 GDSC2 3.4725 5.6182 2.2968 6.0655
SKN-3 GDSC1; GDSC2 3.4732 9.0524 1.2168 17.8381
UPCI-SCC-090 GDSC2 3.5042 7.6666 0.3009 7.0452
YD-8 CTRP2 3.6258 10.3017 1.672 23.3315
BICR 31 GDSC1; GDSC2; CTRP2 3.656 11.8875 0.9536 25.6582
PE/CA-PJ49 CTRP2 3.9083 9.2361 2.4446 19.7519
Detroit 562 GDSC1; GDSC2; CTRP2 3.9527 9.667 2.2906 20.2216
SNU-1214 CTRP2 3.9873 9.9602 2.1882 20.5179
BICR 16 CTRP2 4.0122 9.0516 2.633 18.7601
PE/CA-PJ34 (clone C12) CTRP2 4.1583 10.2534 2.217 19.9787
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 4.1845 9.2436 2.7167 17.996
LB771-HNC GDSC1; GDSC2 4.1882 12.7647 -0.0114 21.1875
BICR 6 CTRP2 4.1984 8.0188 3.2842 15.7333
HSC-3 GDSC1; GDSC2; CTRP2 4.202 10.6398 2.0754 20.3996
OSC-19 GDSC1; GDSC2 4.2303 14.4632 -0.8253 25.9343
KOSC-2 GDSC1; GDSC2 4.2355 10.7146 1.0533 18.3736
BICR 18 CTRP2 4.2435 9.3488 2.7261 17.8107
OSC-20 GDSC1; GDSC2 4.2859 9.5538 1.6759 13.5552
HSC-2 GDSC1; GDSC2; CTRP2 4.3622 11.3328 1.8943 20.6736
SCC-9 GDSC1; GDSC2; CTRP2 4.4621 13.1765 1.0869 23.228
SNU-1066 CTRP2 4.5191 13.2815 1.0874 23.0914
BICR 22 GDSC1; GDSC2; CTRP2 4.7206 10.7028 2.5372 17.3942
PE/CA-PJ41 (clone D2) CTRP2 4.7687 9.6626 3.0868 15.1038
HO-1-N-1 GDSC1; GDSC2 4.8571 13.1415 0.3498 18.1627
SNU-46 CTRP2 4.9419 12.7111 1.7529 19.8292
FaDu GDSC1; GDSC2; CTRP2 5.5056 10.0075 3.5977 11.3623
CAL-27 GDSC1; GDSC2; CTRP2 5.8075 11.94 2.8969 13.6013
BICR 78 GDSC1; GDSC2 5.8469 16.0154 -0.3077 18.5529
BB49-HNC GDSC1; GDSC2 6.0617 8.5277 3.4308 1.9699
KON GDSC1; GDSC2 6.095 13.5815 1.0737 13.7635
SNU-1041 CTRP2 6.0969 13.0384 2.591 14.2365
BICR 56 CTRP2 6.2232 15.0165 1.7065 17.299
SAT [Human HNSCC] GDSC1; GDSC2 6.2325 8.8545 3.3801 1.7843
PCI-38 GDSC1 6.5196 17.3457 -0.4615 23.1528
DOK GDSC1; GDSC2 6.6674 21.9748 -2.6342 24.0087
JHU-022 GDSC1; GDSC2 7.7327 20.8138 -1.2834 18.3166
BICR 10 GDSC1; GDSC2 7.9193 17.1043 0.6225 11.2474
SCC-4 GDSC1; GDSC2; CTRP2 8.1839 20.595 0.4661 17.8629
PCI-30 GDSC1; GDSC2 8.1956 19.1304 -0.1561 13.7594
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JMSU-1 CTRP2 1.7171 6.5548 1.1733 30.638
SW1710 GDSC1; GDSC2; CTRP2 2.2046 5.7453 1.9316 26.5185
253J CTRP2 2.3145 6.4505 1.8562 26.4372
BFTC-905 GDSC1; GDSC2; CTRP2 2.5956 8.227 1.5212 26.7413
RT-112 GDSC1; GDSC2; CTRP2 2.7491 7.4957 1.9688 24.7231
J82 GDSC1; GDSC2; CTRP2 2.8508 10.2494 0.9192 27.9595
TCCSUP GDSC1; GDSC2; CTRP2 2.9077 10.1361 1.0278 27.4565
UM-UC-3 GDSC1; GDSC2; CTRP2 2.9562 7.095 2.3384 22.7777
5637 GDSC1; GDSC2; CTRP2 2.9897 7.4009 2.2622 22.9579
U-BLC1 CTRP2 3.093 7.9614 2.1537 23.0568
CAL-29 GDSC1; GDSC2; CTRP2 3.122 7.5533 2.3455 22.2699
RT-4 GDSC1; GDSC2; CTRP2 3.329 9.3127 1.8239 23.5908
BC-3C CTRP2 3.3369 8.1555 2.3311 21.7156
SCaBER CTRP2 3.4942 10.913 1.2571 25.0996
VM-CUB-1 CTRP2 3.8207 8.9904 2.4676 19.8928
647V GDSC1; GDSC2; CTRP2 3.9997 8.5108 2.8639 17.8975
KMBC-2 CTRP2 4.2735 10.6791 2.1252 20.0377
253J-BV CTRP2 4.881 9.9446 3.0564 14.964
HT-1197 GDSC1; CTRP2 5.4609 12.5553 2.2908 16.6962
T24 GDSC1; GDSC2; CTRP2 5.9015 14.0512 1.9214 17.1635
HT-1376 GDSC1; GDSC2; CTRP2 6.0785 10.0097 4.0901 8.1462
UM-UC-1 CTRP2 6.6356 11.112 3.9849 7.5745
SW780 GDSC1; GDSC2 6.9032 14.1244 1.3689 9.7594
KU-19-19 GDSC1; GDSC2; CTRP2 7.2214 16.6084 1.7084 15.4401
639V GDSC1; GDSC2; CTRP2 9.1871 18.2579 2.3164 10.2048
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1; GDSC2 -1.7628 3.7758 -2.1777 49.5985
BPH-1 GDSC1; GDSC2 -1.2249 2.9194 -1.4144 45.5098
Ca Ski GDSC1; GDSC2 -0.947 4.816 -1.5703 44.1475
C-33 A GDSC1; GDSC2 -0.2958 6.2523 -1.3507 40.4702
PA-1 GDSC1; GDSC2 -0.2381 4.0098 -0.5729 38.2477
ME-180 GDSC1; GDSC2 0.2737 11.5903 -3.0627 40.9746
SW954 GDSC1; GDSC2 0.699 9.0708 -1.4825 39.6704
OVMIU GDSC1; GDSC2 1.1574 5.943 0.3216 29.2139
OV17R GDSC1; GDSC2 1.2325 10.4877 -1.6031 37.7339
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 1.4378 10.0063 -1.1758 35.9638
NT2-D1 GDSC1; GDSC2 1.9118 9.6288 -0.5348 29.6038
NCC-IT GDSC1; GDSC2 1.9436 10.5876 -0.9614 30.8319
ACC-OV7 GDSC1; GDSC2 2.0744 11.8919 -1.4676 34.3538
JAR GDSC1; GDSC2 2.2262 10.4713 -0.636 31.5176
SKN GDSC1; GDSC2 2.593 9.6519 0.1076 25.1348
UWB1.289 GDSC1; GDSC2 2.678 11.3635 -0.6478 29.9995
TC-YIK GDSC2 2.6842 5.9452 0.5645 7.2711
LB831-BLC GDSC1; GDSC2 3.0279 11.0853 -0.1906 24.9617
HEY GDSC1; GDSC2 3.2968 8.3314 1.4098 17.424
PWR-1E GDSC2 3.4097 5.5675 1.2089 2.1039
DSH1 GDSC1; GDSC2 3.4228 10.2726 0.5676 20.8595
JHOS-3 GDSC1; GDSC2 3.8853 11.6181 0.3039 22.7278
C-4-I GDSC1; GDSC2 4.2536 6.3499 3.2505 5.6649
NEC8 GDSC1; GDSC2 4.2673 10.2327 1.3209 15.2966
OVCA433 GDSC1; GDSC2 4.4009 16.2367 -1.5698 27.745
SW962 GDSC1; GDSC2 4.4902 13.3233 -0.0393 22.4242
SiSo GDSC1; GDSC2 4.9715 13.5058 0.2595 18.2677
OVCA420 GDSC1; GDSC2 5.0521 11.8304 1.1575 14.2407
DoTc2 4510 GDSC1; GDSC2 5.0723 9.5339 2.3119 8.6549
HT-3 GDSC1; GDSC2 5.1934 10.7055 1.8241 10.805
SW756 GDSC1; GDSC2 5.6305 10.6551 2.1685 8.2784
JEG-3 GDSC1; GDSC2 5.7816 7.3124 3.7974 0.7373
HeLa GDSC1; GDSC2; CTRP2 6.0641 7.7395 5.2132 3.456
CAL-39 GDSC1; GDSC2 6.2738 15.0456 0.487 14.6346
SKG-IIIa GDSC1; GDSC2 6.2739 8.9659 3.3541 1.8451
HEC-1 GDSC1; GDSC2 6.2929 14.9057 0.5692 14.2614
PEO1 GDSC1; GDSC2 6.4828 9.0601 3.4194 1.4043
MS751 GDSC1; GDSC2 6.8671 15.1958 0.8321 12.1231
SiHa GDSC1; GDSC2 9.0367 20.5341 -0.2726 12.8949
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin. Mol Cancer Ther. 2011 Aug;10(8):1394-406.
2 Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov. 2009 Aug;8(8):627-44.