Details of the Drug

General Information of Drug (ID: DMK1LZD)

Drug Name
Methoxy polyethylene glycol-epoetin beta
Synonyms Mircera (TN)
Indication
Disease Entry ICD 11 Status REF
Kidney transplant rejection NE84 Approved [1]
ATC Code
B03XA03: Methoxy polyethylene glycol-epoetin beta
B03XA: Other antianemic preparations
B03X: OTHER ANTIANEMIC PREPARATIONS
B03: ANTIANEMIC PREPARATIONS
B: BLOOD AND BLOOD FORMING ORGANS
ADMET Property
Half-life
The concentration or amount of drug in body reduced by one-half in 134 +/- 65 hours [2]
Metabolism
The drug is not metabolised []
Vd
The volume of distribution (Vd) of drug is 0.095 L/kg []
Cross-matching ID
UNII
LR3UXN0193
DrugBank ID
DB09107
TTD ID
D0K3XP

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Erythropoietin Receptor (EPOR) TTAUX24 EPOR_HUMAN Activator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Kidney transplant rejection
ICD Disease Classification NE84
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Erythropoietin Receptor (EPOR) DTT EPOR 7.04E-01 0.11 0.27
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 2007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.
2 Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds