Details of the Drug

General Information of Drug (ID: DMK2Y4V)

Drug Name
Ancrod
Synonyms Arvin; Arwin; Venacil; Viprinex; Agkistrodon rhodostoma venom proteinase; Agkistrodon serine proteinase; Snake venom, Knoll
Indication
Disease Entry ICD 11 Status REF
Blood forming organ disorder JB64.1 Phase 3 [1]
ATC Code
B01AD09: Ancrod
B01AD: Enzymes
B01A: ANTITHROMBOTIC AGENTS
B01: ANTITHROMBOTIC AGENTS
B: BLOOD AND BLOOD FORMING ORGANS
ADMET Property
Absorption
The absorption of drug is 100% []
Half-life
The concentration or amount of drug in body reduced by one-half in 3 - 5 hours [2]
Cross-matching ID
UNII
EL55307L15
DrugBank ID
DB05099
TTD ID
D05BII

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Vitamin K-dependent protein C (PROC) TTZUXYS PROC_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00141011) Ancrod (Viprinex for the Treatment of Acute, Ischemic Stroke. U.S. National Institutes of Health.
2 Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
3 Ancrod (Arvin) as an alternative to heparin anticoagulation for cardiopulmonary bypass. Anesthesiology. 1989 Dec;71(6):870-7.