Details of the Drug

General Information of Drug (ID: DMK38MV)

Drug Name
Fulranumab
Indication
Disease Entry ICD 11 Status REF
Arthralgia ME82 Phase 3 [1]
Back pain ME84.Z Phase 3 [1]
Cancer related pain MG30 Phase 3 [1]
Drug Type
Monoclonal antibody
Cross-matching ID
UNII
0E986JU40I
DrugBank ID
DB12102
TTD ID
D0O1GS
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Low-affinity nerve growth factor receptor (NGFR) TTEDJN4 TNR16_HUMAN Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Arthralgia
ICD Disease Classification ME82
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Low-affinity nerve growth factor receptor (NGFR) DTT NGFR 5.08E-01 0.38 0.37
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT02336685) Study of Efficacy, Safety of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3001. U.S. National Institutes of Health.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1888).