Details of the Drug

General Information of Drug (ID: DMK4Y71)

Drug Name
N-acylpyrrolidine ether derivative 2
Synonyms PMID28270021-Compound-WO2016020784Example12
Indication
Disease Entry ICD 11 Status REF
Chronic pain MG30 Patented [1]
Neuropathic pain 8E43.0 Patented [1]
Pruritus EC90 Patented [1]
Solid tumour/cancer 2A00-2F9Z Patented [1]
Thymic cancer 2C27 Patented [1]
Structure 3D Structure is Not Available
3D MOL 2D MOL
Cross-matching ID
TTD ID
D08BIH
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tropomyosin-related kinase A (TrkA) TTTDVOJ NTRK1_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Chronic pain
ICD Disease Classification MG30
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tropomyosin-related kinase A (TrkA) DTT NTRK1 8.72E-01 -0.04 -0.22
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Tropomyosin receptor kinase inhibitors: an updated patent review for 2010-2016 - Part II.Expert Opin Ther Pat. 2017 Jul;27(7):831-849.