Details of the Drug

General Information of Drug (ID: DMK8LEC)

Drug Name
OF-1
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 440.3
Logarithm of the Partition Coefficient (xlogp) 2.5
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C17H18BrN3O4S
IUPAC Name
4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxobenzimidazol-5-yl)-2-methylbenzenesulfonamide
Canonical SMILES
CC1=C(C=CC(=C1)Br)S(=O)(=O)NC2=CC3=C(C=C2OC)N(C(=O)N3C)C
InChI
InChI=1S/C17H18BrN3O4S/c1-10-7-11(18)5-6-16(10)26(23,24)19-12-8-13-14(9-15(12)25-4)21(3)17(22)20(13)2/h5-9,19H,1-4H3
InChIKey
YUNQZQREIHWDQT-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
35397514
TTD ID
D08RDI

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bromodomain and PHD finger containing 1 (BRPF1) TTT46BN BRPF1_HUMAN Inhibitor [2]
Bromodomain-containing protein 1 (BRD1) TTT09OB BRD1_HUMAN Inhibitor [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 5.8463 7.8764 2.6519 0.5844
NOS-1 [Human HNSCC] GDSC2 3.2893 5.2421 2.3345 6.3473
SK-PN-DW GDSC2 3.4067 6.4662 1.8198 9.2567
TC-71 GDSC2 3.8331 7.4135 1.685 8.9436
CHSA8926 GDSC2 4.1615 8.6234 1.3342 10.2453
CADO-ES1 GDSC2 4.1626 6.5597 2.3386 4.1634
EW-12 GDSC2 4.2069 6.7801 2.2631 4.5245
MG-63 GDSC2 4.3237 9.3078 1.1173 11.1222
A-673 GDSC2 4.3359 10.4133 0.5817 14.0962
CAL-78 GDSC2 4.4006 8.3692 1.6309 7.9074
EW-1 GDSC2 4.4256 9.4555 1.1193 10.8645
SaOS-2 GDSC2 4.4612 6.5131 2.546 2.4243
ES5 GDSC2 4.5677 8.4785 1.6935 7.1687
EW-11 GDSC2 4.7013 7.7367 2.1308 4.3448
EW-13 GDSC2 4.8789 10.3392 1.0109 10.4372
HOS GDSC2 4.9537 9.9857 1.2322 9.0264
EW-3 GDSC2 5.0019 9.0078 1.7273 6.0984
EW-18 GDSC2 5.0284 9.0613 1.7191 6.0952
G-292 clone A141B1 GDSC2 5.1345 11.8923 0.4372 12.9563
CHSA0108 GDSC2 5.2234 8.3564 2.157 3.3439
H-EMC-SS GDSC2 5.27 8.1846 2.2579 2.7567
ES7 GDSC2 5.2863 15.3257 -1.1319 19.726
EW-24 GDSC2 5.3586 6.6724 2.8977 0.1957
HuO9 GDSC2 5.3601 8.4915 2.173 3.0649
U2OS GDSC2 5.4095 12.2393 0.4602 12.2343
ES6 GDSC2 5.4531 7.9996 2.4299 1.7159
CAL-72 GDSC2 5.4629 8.4484 2.2464 2.5617
SK-ES-1 GDSC2 5.5263 7.1524 2.7903 0.3685
HuO-3N1 GDSC2 5.6378 13.9484 -0.2069 14.992
EW-7 GDSC2 5.6425 7.7607 2.6112 0.8343
U-CH2 GDSC2 5.6485 7.7192 2.6296 0.7689
EW-16 GDSC2 5.6792 8.3174 2.4082 1.5824
EW-22 GDSC2 5.9467 8.1098 2.6059 0.664
ES4 GDSC2 6.0253 8.2659 2.5797 0.6979
CHSA0011 GDSC2 6.0491 17.6174 -1.7002 20.1499
ES8 GDSC2 6.071 7.9552 2.7103 0.3419
MHH-ES-1 GDSC2 6.0994 11.6518 1.1809 7.1292
NY GDSC2 6.2539 17.7167 -1.6025 19.3748
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 157 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 2.226 6.8472 0.5795 20.5277
MOLT-4 GDSC2 0.8001 1.6959 0.7984 25.3151
SK-MM-2 GDSC2 1.1526 4.3476 0.6124 24.6618
HL-60 GDSC2 1.4644 3.4549 1.257 19.7394
SUP-M2 GDSC2 1.666 6.5222 0.1952 24.6922
ATN-1 GDSC2 1.7836 4.144 1.3642 17.7413
Jurkat GDSC2 1.8904 3.8893 1.5748 16.0848
Karpas-231 GDSC2 2.1907 4.6177 1.5928 14.7492
LP-1 GDSC2 2.267 5.9517 1.05 17.6944
DoHH2 GDSC2 2.3608 4.6154 1.7669 13.0489
JJN-3 GDSC2 2.5518 6.5204 1.0429 16.7253
L-1236 GDSC2 2.6531 5.4125 1.6777 12.5253
K-562 GDSC2 3.0724 5.8864 1.8263 10.2142
MM1.S GDSC2 3.1754 7.2811 1.2189 13.6496
AMO1 GDSC2 3.2158 4.704 2.5406 5.2642
MOLT-13 GDSC2 3.2934 6.3304 1.7939 9.7477
KMS-12-BM GDSC2 3.342 6.2081 1.8955 8.967
L-540 GDSC2 3.3694 7.0807 1.482 11.4671
BC-1 GDSC2 3.3827 5.9446 2.0609 7.8069
SUP-B8 GDSC2 3.4754 5.9493 2.1339 7.0862
VL51 GDSC2 3.4756 6.1059 2.0558 7.5779
A4/Fukuda GDSC2 3.4895 5.6386 2.3001 5.9984
OCI-M1 GDSC2 3.5373 6.4729 1.9221 8.2501
SU-DHL-6 GDSC2 3.539 5.5882 2.3642 5.4612
Raji GDSC2 3.5411 6.0227 2.1496 6.8083
DG-75 GDSC2 3.5415 11.0865 -0.3789 21.0704
MC116 GDSC2 3.5979 5.749 2.33 5.5223
OCI-AML-3 GDSC2 3.6111 6.3503 2.0414 7.3015
BL-41 GDSC2 3.6339 7.5664 1.4537 10.8946
KE-37 GDSC2 3.6578 8.5436 0.9854 13.6295
KY821 GDSC2 3.6657 6.6004 1.9597 7.67
SKM-1 GDSC2 3.6843 5.6327 2.4529 4.5342
MOLM-16 GDSC2 3.6866 6.3597 2.0952 6.7669
SIG-M5 GDSC2 3.708 8.9705 0.8126 14.4838
MN-60 GDSC2 3.7432 6.9281 1.8567 8.1107
WSU-NHL GDSC2 3.7519 5.4181 2.607 3.4188
Kasumi-1 GDSC2 3.7561 7.2057 1.729 8.8709
OCI-Ly19 GDSC2 3.7624 9.3242 0.6795 15.0797
SU-DHL-8 GDSC2 3.7711 5.2846 2.6851 2.8983
RS4;11 GDSC2 3.7747 8.3138 1.1926 12.0883
NCI-H929 GDSC2 3.7855 6.3046 2.1971 5.8809
TALL-1 [Human adult T-ALL] GDSC2 3.7861 5.8742 2.4089 4.5629
Hs 445 GDSC2 3.7903 10.2275 0.2513 17.2986
OCI-AML-2 GDSC2 3.8086 6.7571 1.9911 7.1069
RCH-ACV GDSC2 3.8373 7.9216 1.4362 10.4562
Karpas-422 GDSC2 3.8419 5.9065 2.4332 4.283
Ramos.2G6.4C10 GDSC2 3.8566 6.3263 2.2387 5.4509
ALL-PO GDSC2 3.8667 6.9127 1.9579 7.1692
KM-H2 GDSC2 3.8771 7.4515 1.6995 8.7416
WIL2 NS GDSC2 3.8964 7.0027 1.9356 7.2336
HAL-01 GDSC2 3.901 7.5431 1.6724 8.8481
EoL-1 GDSC2 3.9211 9.0476 0.9418 13.1636
MOLP-8 GDSC2 3.9248 7.4407 1.7408 8.3673
VAL GDSC2 3.9257 6.5671 2.1709 5.707
A3/Kawakami GDSC2 3.972 5.2064 2.8505 1.5412
THP-1 GDSC2 3.9798 7.6973 1.6554 8.7547
MHH-PREB-1 GDSC2 3.988 7.0475 1.9809 6.7324
Reh GDSC2 3.9901 7.3197 1.8489 7.5408
P12-Ichikawa GDSC2 3.9929 5.5405 2.7095 2.3057
NK-92MI GDSC2 4.0107 7.9642 1.5468 9.3403
U266B1 GDSC2 4.0168 6.2401 2.3935 4.1387
RPMI-8226 GDSC2 4.0793 7.3058 1.9205 6.8886
GR-ST GDSC2 4.0985 7.587 1.7968 7.6008
Karpas-45 GDSC2 4.14 7.7948 1.7252 7.9397
EJM GDSC2 4.1482 6.6195 2.3005 4.4219
SU-DHL-5 GDSC2 4.1568 5.5592 2.7986 1.5328
CTV-1 GDSC2 4.2046 6.3354 2.4719 3.2914
OCI-AML-5 GDSC2 4.2147 8.9976 1.1894 10.9693
QIMR-WIL GDSC2 4.2226 6.4218 2.4429 3.4269
L-363 GDSC2 4.2303 5.8571 2.7075 1.9102
JURL-MK1 GDSC2 4.2379 6.996 2.1808 4.954
OPM-2 GDSC2 4.2433 6.3096 2.5083 3.0078
DEL GDSC2 4.2562 5.7827 2.7553 1.6144
OCI-Ly7 GDSC2 4.2582 5.7769 2.7589 1.5926
JSC-1 GDSC2 4.2618 8.2186 1.6058 8.3764
Karpas-620 GDSC2 4.2749 6.16 2.5964 2.451
SU-DHL-16 GDSC2 4.2791 5.6384 2.8306 1.1979
Ku812 GDSC2 4.2846 7.7034 1.8724 6.7141
MOLT-16 GDSC2 4.2875 11.1976 0.157 16.4394
ME1 GDSC2 4.288 9.2508 1.119 11.1995
RL GDSC2 4.2973 7.7117 1.8771 6.6573
RPMI-6666 GDSC2 4.3089 6.1463 2.6228 2.2483
CCRF-CEM GDSC2 4.3158 8.1534 1.676 7.829
Daudi GDSC2 4.3183 6.1163 2.6418 2.1286
KMOE-2 GDSC2 4.3225 10.3345 0.6106 13.9739
NB4 GDSC2 4.3245 5.742 2.8099 1.2416
MHH-CALL-4 GDSC2 4.3283 7.2775 2.1069 5.2081
EB2 GDSC2 4.3455 6.7658 2.3599 3.6783
NOMO-1 GDSC2 4.346 7.5705 1.9786 5.9399
BC-3 GDSC2 4.3805 8.4298 1.5874 8.2135
MY-M12 GDSC2 4.3867 9.0202 1.3041 9.88
DND-41 GDSC2 4.4079 9.9078 0.8844 12.2464
NU-DUL-1 GDSC2 4.4218 6.0749 2.7179 1.5739
SUP-HD1 GDSC2 4.4571 7.7954 1.9458 5.9024
H9 GDSC2 4.4847 7.5517 2.0798 5.0518
RPMI-8866 GDSC2 4.4855 8.6174 1.57 8.0808
BONNA-12 GDSC2 4.4982 7.0537 2.3214 3.6199
NALM-6 GDSC2 4.4991 8.2144 1.7736 6.8397
KOPN-8 GDSC2 4.5065 6.3048 2.6636 1.7349
MEG-01 GDSC2 4.5244 6.9124 2.4023 3.1161
CRO-AP2 GDSC2 4.5279 7.6561 2.0586 5.0913
JeKo-1 GDSC2 4.5795 10.7974 0.5734 13.5365
SU-DHL-1 GDSC2 4.6217 13.3443 -0.6515 19.3556
HEL GDSC2 4.6234 7.9214 1.9953 5.2755
MLMA GDSC2 4.6472 8.185 1.8863 5.8669
RC-K8 GDSC2 4.6482 6.3591 2.7144 1.307
SU-DHL-4 GDSC2 4.6514 6.7444 2.5504 2.1152
HDLM-2 GDSC2 4.6765 7.1718 2.3744 3.0187
SUP-T1 GDSC2 4.6799 6.8397 2.5243 2.2107
ALL-SIL GDSC2 4.6986 6.9048 2.506 2.2792
SR GDSC2 4.717 6.7504 2.5833 1.8577
U-698-M GDSC2 4.7496 7.5813 2.2317 3.689
LAMA-84 GDSC2 4.7516 8.9194 1.6063 7.2947
MOLM-13 GDSC2 4.7588 7.0985 2.454 2.4644
TUR GDSC2 4.7592 7.112 2.4482 2.4938
BALL-1 GDSC2 4.7855 6.875 2.5658 1.8552
CESS GDSC2 4.7855 6.9591 2.5295 2.0369
LC4-1 GDSC2 4.8411 7.6542 2.2526 3.4211
CA46 GDSC2 4.8572 7.3779 2.3854 2.681
P30/OHK GDSC2 4.8858 11.3997 0.5005 13.1949
IM-9 GDSC2 4.9501 9.6274 1.4011 8.0707
CML-T1 GDSC2 4.9745 7.2083 2.5218 1.8329
ST486 GDSC2 4.9996 6.6364 2.7674 0.7475
ML-2 GDSC2 5.0718 6.8789 2.7043 0.9288
GA-10 GDSC2 5.0746 6.5036 2.8495 0.4266
Karpas-1106P GDSC2 5.1247 7.562 2.4489 2.0002
HT GDSC2 5.1253 10.4473 1.1269 9.2582
Granta-519 GDSC2 5.1755 7.3573 2.5597 1.4327
Karpas-299 GDSC2 5.1815 6.5942 2.8587 0.3481
P32/ISH GDSC2 5.1909 6.4228 2.9234 0.1971
SUP-B15 GDSC2 5.2154 7.3677 2.5745 1.3285
PF-382 GDSC2 5.282 6.9557 2.7654 0.562
KMS-11 GDSC2 5.3049 10.6166 1.1652 8.6787
Namalwa GDSC2 5.3518 6.8707 2.8247 0.3586
ROS-50 GDSC2 5.3963 9.8632 1.5759 6.2254
SU-DHL-10 GDSC2 5.4767 6.429 3.02 0.03
KCL-22 GDSC2 5.4768 7.2853 2.7219 0.5816
Farage GDSC2 5.5159 6.9752 2.8495 0.2406
MHH-CALL-2 GDSC2 5.5208 7.199 2.7713 0.4191
L-428 GDSC2 5.5393 7.2475 2.7609 0.4377
SCC-3 GDSC2 5.5421 14.077 -0.3365 15.7934
TK [Human B-cell lymphoma] GDSC2 5.5669 7.0768 2.8326 0.258
Jiyoye GDSC2 5.5881 7.8875 2.5382 1.1403
EM-2 GDSC2 5.6031 7.3097 2.7632 0.4028
HC-1 GDSC2 5.6037 7.1506 2.8203 0.2711
Loucy GDSC2 5.6131 7.2499 2.7886 0.3373
ARH-77 GDSC2 5.6653 7.1755 2.8342 0.2244
DB GDSC2 5.7403 7.605 2.7095 0.4791
HH [Human lymphoma] GDSC2 5.764 7.6978 2.6849 0.5342
PL-21 GDSC2 5.7859 8.345 2.4465 1.3301
697 GDSC2 5.7903 7.2211 2.8632 0.1459
KG-1 GDSC2 5.9554 7.7517 2.7391 0.3211
BE-13 GDSC2 5.956 7.9901 2.6537 0.5247
JVM-3 GDSC2 5.9889 7.6958 2.771 0.2477
JVM-2 GDSC2 6.0086 8.3105 2.5562 0.7794
GDM-1 GDSC2 6.0494 7.761 2.7703 0.2322
CTB-1 GDSC2 6.4238 8.4271 2.6749 0.2997
⏷ Show the Full List of 157 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC2 1.9165 3.8452 1.6191 15.7209
HCE-4 GDSC2 3.4579 8.9229 0.6339 16.2014
ESO-51 GDSC2 3.8052 7.7776 1.4829 10.2566
FLO-1 GDSC2 3.8915 7.6533 1.6107 9.2509
KYSE-220 GDSC2 4.8316 8.196 1.9986 4.8635
TE-12 GDSC2 5.0043 12.1597 0.2146 14.3875
ESO-26 GDSC2 5.1466 17.5825 -2.3506 24.2808
OACP4 C GDSC2 5.224 9.5703 1.6048 6.3775
SK-GT-4 GDSC2 5.4519 12.5979 0.3167 12.8719
KYAE-1 GDSC2 5.5939 7.1475 2.8177 0.2799
OACM5.1 C GDSC2 5.925 8.2847 2.531 0.9147
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 4.6961 8.7677 1.6416 7.2035
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-YN GDSC2 3.598 7.304 1.556 10.3644
CHP-212 GDSC2 3.7857 13.258 -1.2651 24.0335
SJNB-14 GDSC2 3.9164 7.0927 1.9061 7.3674
SJNB-7 GDSC2 3.9342 7.3304 1.8023 7.9651
CHP-126 GDSC2 4.0201 6.5841 2.2297 5.1287
SK-N-DZ GDSC2 4.0746 8.2513 1.453 9.749
SJNB-5 GDSC2 4.1008 7.9667 1.6124 8.7199
NB(TU)1 GDSC2 4.1678 6.2612 2.4832 3.2956
SK-N-MC-IXC GDSC2 4.3988 10.7457 0.4648 14.5627
NH-12 GDSC2 4.4586 7.0751 2.2869 3.8906
Kelly GDSC2 4.523 7.9178 1.9314 5.8522
SJNB-6 GDSC2 4.5683 7.5444 2.137 4.555
SJNB-13 GDSC2 4.5711 7.507 2.1562 4.4381
GI-ME-N GDSC2 4.6403 8.4358 1.7627 6.6078
SJNB-17 GDSC2 4.6707 8.7534 1.6314 7.3168
TGW GDSC2 4.7305 6.9155 2.5188 2.1671
SK-N-BE(2)-M17 GDSC2 4.7334 7.3484 2.3278 3.1827
SiMa GDSC2 4.7894 12.8677 -0.2901 17.3301
MHH-NB-11 GDSC2 4.8233 8.2701 1.9591 5.1054
SJNB-10 GDSC2 4.9578 7.172 2.5287 1.8201
NB69 GDSC2 4.9742 13.0883 -0.262 16.7551
GOTO GDSC2 5.5124 8.5145 2.2439 2.5121
CHP-134 GDSC2 5.5334 7.0235 2.839 0.2561
KP-N-YS GDSC2 5.6122 7.6692 2.6333 0.7802
IMR-5 GDSC2 5.6485 7.6048 2.6727 0.6321
SK-N-AS GDSC2 5.6547 7.1552 2.8375 0.2215
LA-N-6 GDSC2 5.6604 7.3523 2.7699 0.3622
KP-N-RT-BM-1 GDSC2 5.6852 7.8408 2.5988 0.8475
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 4.063 7.4348 1.8457 7.3858
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1954 GDSC2 0.6388 3.1252 0.445 27.9213
MDA-MB-453 GDSC2 1.5644 5.2935 0.6538 22.6766
OCUB-M GDSC2 1.7443 4.0032 1.3757 17.843
HCC2218 GDSC2 1.9197 5.485 0.9278 19.7144
MDA-MB-157 GDSC2 2.293 4.5522 1.7263 13.5542
MDA-MB-468 GDSC2 2.3592 6.3528 0.9447 17.9773
BT-20 GDSC2 2.9562 4.5141 2.3992 7.0004
HCC1187 GDSC2 3.2418 8.3712 0.7302 16.307
MCF-7 GDSC2 3.2951 6.4009 1.76 9.9546
UACC-893 GDSC2 3.3143 10.2769 -0.1619 20.7355
MRK-nu-1 GDSC2 3.5475 7.0528 1.641 9.9779
HCC1428 GDSC2 3.7457 5.6789 2.4752 4.2474
CAMA-1 GDSC2 3.7758 6.7991 1.9456 7.4732
HCC1599 GDSC2 3.8741 6.5207 2.1561 5.9205
HCC1419 GDSC2 3.8982 6.9583 1.9588 7.0857
BT-474 GDSC2 3.9402 7.2604 1.8412 7.7099
HCC1500 GDSC2 4.1287 7.7332 1.7472 7.8324
MDA-MB-361 GDSC2 4.1447 6.4982 2.3561 4.0957
HDQ-P1 GDSC2 4.173 6.7918 2.2348 4.7655
T-47D GDSC2 4.2498 15.2274 -1.8763 24.9444
HCC70 GDSC2 4.2904 11.979 -0.2284 18.3053
Evsa-T GDSC2 4.435 9.5798 1.0652 11.1533
CAL-85-1 GDSC2 4.4545 7.0057 2.3166 3.7268
MFM-223 GDSC2 4.4704 6.8268 2.409 3.1708
COLO 824 GDSC2 4.5265 6.9193 2.4004 3.123
DU4475 GDSC2 4.5596 6.4204 2.642 1.7725
EFM-19 GDSC2 4.5863 7.8432 2.0082 5.2726
HCC1806 GDSC2 4.6233 7.3128 2.2785 3.6428
MDA-MB-436 GDSC2 4.6241 14.6663 -1.305 21.9798
CAL-120 GDSC2 4.6245 6.9568 2.441 2.7378
HCC1569 GDSC2 4.7404 7.2145 2.392 2.8221
ZR-75-30 GDSC2 4.7592 9.7869 1.1948 9.6619
HCC2157 GDSC2 4.8984 6.9154 2.6067 1.5212
YMB-1-E GDSC2 4.9078 9.1208 1.6137 6.9339
HCC38 GDSC2 4.9847 7.0038 2.6127 1.3982
MDA-MB-231 GDSC2 5.0956 7.4087 2.4989 1.7974
HCC1937 GDSC2 5.2167 9.832 1.478 7.1043
MDA-MB-330 GDSC2 5.3183 15.0876 -0.9915 19.0957
EFM-192A GDSC2 5.4426 7.9066 2.463 1.5816
AU565 GDSC2 5.4581 12.8709 0.1892 13.4933
JIMT-1 GDSC2 5.4902 7.3332 2.7095 0.6117
BT-549 GDSC2 5.5007 7.7048 2.571 1.0862
CAL-51 GDSC2 5.571 11.8528 0.7538 10.3684
HCC1143 GDSC2 5.6453 12.6872 0.4054 12.0152
Hs 578T GDSC2 5.6523 7.534 2.7006 0.5476
MDA-MB-415 GDSC2 6.1181 13.9166 0.1345 12.3881
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-423MG GDSC2 2.3944 8.4545 -0.0532 23.2026
Onda 10 GDSC2 2.8322 7.6699 0.7275 17.6114
GB-1 GDSC2 3.3347 8.1368 0.9252 14.9108
LN-405 GDSC2 3.388 5.2509 2.4119 5.5726
D-263MG GDSC2 3.992 14.3669 -1.6525 24.8633
KNS-42 GDSC2 4.0162 7.3706 1.843 7.514
YKG-1 GDSC2 4.0466 7.1685 1.964 6.6984
SF295 GDSC2 4.0519 7.2414 1.9322 6.8812
Hs 683 GDSC2 4.1362 6.4124 2.3912 3.903
LN-18 GDSC2 4.1373 8.4472 1.403 9.894
KS-1 [Human Krukenberg tumour] GDSC2 4.1597 10.3807 0.4641 15.1811
U-87MG ATCC GDSC2 4.175 6.5169 2.3672 3.9674
Onda 11 GDSC2 4.2122 9.9134 0.7355 13.569
NMC-G1 GDSC2 4.2414 8.4557 1.4751 9.2097
GaMG GDSC2 4.2454 7.6803 1.8562 6.9
CAS-1 GDSC2 4.2471 8.1037 1.6514 8.1357
SF539 GDSC2 4.4042 6.5864 2.4791 2.8894
KNS-81-FD GDSC2 4.545 8.3117 1.7581 6.8342
8-MG-BA GDSC2 4.594 6.5792 2.5914 1.9841
U-118MG GDSC2 4.6154 6.2447 2.7458 1.1985
D-542MG GDSC2 4.6451 7.2262 2.3312 3.3097
SF268 GDSC2 4.6511 7.5146 2.2025 4.0252
D-247MG GDSC2 4.6808 7.3889 2.2783 3.5447
H4 GDSC2 4.6867 6.9831 2.4647 2.5145
ONS-76 GDSC2 4.6886 6.7987 2.547 2.0806
LN-229 GDSC2 4.7219 8.6079 1.7349 6.604
SNB-75 GDSC2 4.748 9.7745 1.1929 9.6975
D-392MG GDSC2 4.7666 11.4819 0.3743 14.1341
SK-MG-1 GDSC2 4.7786 11.0402 0.5992 12.9225
Becker GDSC2 4.8441 6.7152 2.6632 1.3224
SW1088 GDSC2 4.9756 8.5696 1.9147 5.0803
Daoy GDSC2 5.0569 9.6763 1.4482 7.5851
AM-38 GDSC2 5.1572 7.0548 2.6732 0.9777
D-502MG GDSC2 5.1672 7.7197 2.4037 2.1663
DK-MG GDSC2 5.238 6.599 2.8787 0.2757
GI-1 GDSC2 5.2711 18.9424 -2.9293 25.6787
U-251MG GDSC2 5.287 11.4936 0.7351 11.0574
A-172 GDSC2 5.2883 7.5634 2.5295 1.4494
YH-13 GDSC2 5.3375 7.1076 2.7312 0.6366
M059J GDSC2 5.3392 7.2515 2.6768 0.8205
D-336MG GDSC2 5.3614 10.9631 1.0381 9.2647
D283 Med GDSC2 5.3986 6.773 2.8771 0.223
DBTRG-05MG GDSC2 5.5689 8.0369 2.4698 1.4299
42-MG-BA GDSC2 5.6308 7.5462 2.6874 0.598
PFSK-1 GDSC2 5.6842 10.8886 1.2792 7.3332
D-566MG GDSC2 5.6867 7.3507 2.7805 0.3276
SF126 GDSC2 5.8924 7.3178 2.8661 0.1227
T98G GDSC2 5.981 14.1133 -0.0509 13.5426
D-245MG GDSC2 6.1831 8.6965 2.4831 0.9044
KINGS-1 GDSC2 6.3779 8.272 2.7121 0.2462
KALS-1 GDSC2 7.0112 9.2403 2.6054 0.2647
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC2 2.1181 7.5934 0.1154 23.3637
ETK-1 GDSC2 5.3077 7.7423 2.4653 1.713
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-296 GDSC2 2.1087 3.6035 1.9116 13.2351
RL95-2 GDSC2 3.2336 7.7693 1.0242 14.6343
MFE-280 GDSC2 4.139 8.1948 1.5284 9.1357
KLE GDSC2 4.4359 7.9064 1.8784 6.349
MFE-319 GDSC2 4.4554 10.1871 0.7821 12.7017
EN GDSC2 4.5827 10.2947 0.8222 12.1713
AN3-CA GDSC2 5.2953 9.3507 1.7502 5.4373
ESS-1 GDSC2 5.552 7.165 2.7957 0.3449
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-498 GDSC2 3.6644 6.738 1.8903 8.1077
RCC10RGB GDSC2 3.7678 5.3067 2.6721 2.9846
CAL-54 GDSC2 4.0537 7.3034 1.9032 7.0547
KMRC-20 GDSC2 4.0913 6.7106 2.218 5.0422
LB1047-RCC GDSC2 4.0929 9.4605 0.8691 13.1273
SW13 GDSC2 4.1445 6.4219 2.3922 3.8801
LB996-RCC GDSC2 4.1627 8.9779 1.1604 11.269
BB65-RCC GDSC2 4.3367 7.0495 2.2209 4.5124
A-704 GDSC2 4.3426 6.3044 2.571 2.4792
KTCTL-13 GDSC2 4.3637 11.4542 0.088 16.5878
OS-RC-2 GDSC2 4.5573 10.2711 0.8154 12.2699
KTCTL-140 GDSC2 4.5815 7.852 2.0009 5.3247
KTCTL-26A GDSC2 4.6076 7.4703 2.1961 4.1404
UO-31 GDSC2 4.6632 8.5331 1.7315 6.7439
769-P GDSC2 4.73 10.6084 0.7751 12.0833
KTCTL-21 GDSC2 4.7647 10.6268 0.7909 11.9159
SN12C GDSC2 4.7975 7.3596 2.3598 2.9076
VMRC-RCZ GDSC2 4.8431 6.8854 2.5914 1.6586
BFTC-909 GDSC2 4.9174 11.9701 0.2447 14.439
NCC010 GDSC2 4.9208 7.1356 2.525 1.8837
TK-10 GDSC2 5.0483 7.9575 2.2356 3.1894
LB2241-RCC GDSC2 5.1009 7.3665 2.5193 1.6959
HA7-RCC GDSC2 5.2722 11.944 0.5081 12.2841
VMRC-RCW GDSC2 5.5792 12.0007 0.6889 10.6932
KTCTL-195 GDSC2 5.5999 7.9069 2.5358 1.1396
SW156 GDSC2 5.8309 10.1187 1.7166 4.7475
786-O GDSC2 5.8674 7.4805 2.8017 0.2264
KTCTL-1M GDSC2 5.8914 8.4086 2.4686 1.1597
NCC021 GDSC2 5.9576 18.2195 -2.0608 21.5708
ACHN GDSC2 6.0978 14.4101 -0.1143 13.5997
RXF 393L GDSC2 6.1351 8.89 2.3881 1.2679
Caki-1 GDSC2 6.6027 15.1823 -0.1477 12.7636
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 GDSC2 3.471 6.5531 1.8288 9.0184
C2BBe1 GDSC2 3.5647 9.8971 0.2344 18.0289
HT-55 GDSC2 3.7447 5.7776 2.4261 4.5546
COLO 678 GDSC2 3.873 13.6754 -1.4031 24.302
CaR-1 GDSC2 3.8919 7.466 1.7036 8.679
SNU-1040 GDSC2 3.9034 7.8505 1.5222 9.7617
COLO 320HSR GDSC2 3.996 7.272 1.8766 7.3559
SW626 GDSC2 4.0205 8.0299 1.5217 9.4681
SW48 GDSC2 4.0406 15.4148 -2.1365 26.3173
NCI-H508 GDSC2 4.0649 6.1009 2.4921 3.4457
SK-CO-1 GDSC2 4.0825 7.053 2.046 6.1125
SW1116 GDSC2 4.1758 9.1149 1.1026 11.5736
LS411N GDSC2 4.1976 12.0756 -0.3483 19.1051
LS180 GDSC2 4.2035 6.2029 2.5331 2.938
SNU-61 GDSC2 4.2693 6.8645 2.2644 4.3893
SNU-283 GDSC2 4.2854 9.0424 1.2195 10.6193
HCT 116 GDSC2 4.3009 7.4397 2.0108 5.8432
DiFi GDSC2 4.3051 7.8944 1.7942 7.1409
SW837 GDSC2 4.3329 8.0873 1.7202 7.5243
CW-2 GDSC2 4.357 6.8549 2.3255 3.857
LoVo GDSC2 4.4435 7.1212 2.2559 4.0991
RKO GDSC2 4.4763 7.8534 1.931 5.9505
LS513 GDSC2 4.4961 7.1149 2.2918 3.7937
MDST8 GDSC2 4.5132 7.2542 2.2377 4.0744
RCM-1 [Human ESC] GDSC2 4.5382 6.2337 2.7111 1.4553
HCC2998 GDSC2 4.5808 8.6058 1.6413 7.4496
NCI-H716 GDSC2 4.5826 12.5312 -0.2789 17.7909
SW948 GDSC2 4.6974 8.3603 1.8361 6.0608
SNU-175 GDSC2 4.7571 10.3826 0.9044 11.3065
SNU-C1 GDSC2 4.7776 8.0383 2.0383 4.7355
SW1463 GDSC2 4.8173 12.0049 0.1549 15.1274
HT-29 GDSC2 4.8362 8.6497 1.7896 6.0583
SW620 GDSC2 4.8388 10.5458 0.8827 11.2404
HT115 GDSC2 4.8398 13.4113 -0.5204 18.2454
SW1417 GDSC2 4.8609 8.5304 1.8613 5.5971
CL-11 GDSC2 4.9395 10.8361 0.8126 11.3984
LS123 GDSC2 4.9699 8.5077 1.9399 4.9483
CCK-81 GDSC2 4.9755 8.6436 1.8804 5.275
COLO205 GDSC2 5.0191 7.0851 2.5959 1.4367
GP5d GDSC2 5.0965 9.0143 1.7836 5.6033
NCI-H747 GDSC2 5.2066 7.4787 2.5248 1.5545
T84 GDSC2 5.2815 7.6 2.5112 1.5361
HCT 15 GDSC2 5.5321 7.067 2.8231 0.2901
LS1034 GDSC2 5.6834 7.4489 2.744 0.4158
KM12 GDSC2 5.7684 7.8144 2.6434 0.6521
SNU-C2B GDSC2 5.8915 13.1799 0.3349 11.8646
SNU-407 GDSC2 5.9262 7.8527 2.692 0.4401
SNU-C5 GDSC2 6.0738 8.0602 2.674 0.4222
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 4.2919 7.0368 2.1973 4.7428
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-7 GDSC2 1.2503 4.4299 0.6851 23.838
Huh-7 GDSC2 1.6088 3.305 1.457 17.9903
JHH-4 GDSC2 2.7155 7.8748 0.5223 19.1376
JHH-1 GDSC2 2.7781 7.9704 0.5302 18.887
Hep-G2/C3A GDSC2 3.4325 6.3613 1.8934 8.7216
HuH-1 GDSC2 3.6547 5.3032 2.5931 3.733
Hep 3B2.1-7 GDSC2 4.1593 6.8456 2.1997 5.0063
SK-HEP-1 GDSC2 4.2129 7.9888 1.6829 8.0251
JHH-2 GDSC2 4.3805 10.0236 0.8072 12.7464
SNU-387 GDSC2 4.594 10.0611 0.9447 11.4604
HLE GDSC2 4.7993 10.0737 1.0839 10.2032
SNU-398 GDSC2 4.9057 13.3298 -0.4313 17.6894
JHH-6 GDSC2 5.2014 10.8321 0.9941 9.8352
SNU-423 GDSC2 5.6385 7.4663 2.72 0.5002
SNU-449 GDSC2 5.9124 9.334 2.1016 2.7065
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 166 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H23 GDSC2 1.398 6.4971 -0.0583 27.0249
Lu-99A GDSC2 2.401 8.4871 -0.0632 23.228
DMS 53 GDSC2 2.4282 8.4791 -0.0347 22.9952
Calu-3 GDSC2 2.8976 7.69 0.7749 17.1301
ABC-1 GDSC2 3.06 9.4006 0.0617 20.4302
NCI-H810 GDSC2 3.2644 6.7872 1.5411 11.4104
A-427 GDSC2 3.2658 8.721 0.5755 17.0964
NCI-H526 GDSC2 3.3133 6.8656 1.5429 11.2549
COLO 668 GDSC2 3.4183 9.3229 0.4013 17.5829
NCI-H1581 GDSC2 3.4583 6.8688 1.6608 10.1042
BEN GDSC2 3.5688 8.0717 1.1495 12.9129
NCI-H2135 GDSC2 3.5928 6.4946 1.9553 7.8909
NCI-H2444 GDSC2 3.6143 5.8436 2.2957 5.6952
NCI-H1623 GDSC2 3.6554 6.9835 1.7611 8.9375
NCI-H1944 GDSC2 3.6907 9.2457 0.6615 15.3805
NCI-H510A GDSC2 3.7141 7.2612 1.6689 9.3538
NCI-H2196 GDSC2 3.7158 6.4578 2.0689 6.8564
EKVX GDSC2 3.7689 10.3656 0.1653 17.799
NCI-H1436 GDSC2 3.7773 5.4452 2.6117 3.333
SHP-77 GDSC2 3.7989 6.2806 2.2188 5.7129
NCI-H1694 GDSC2 3.8043 6.4798 2.1248 6.2851
EMC-BAC-2 GDSC2 3.8084 6.804 1.9678 7.2526
NCI-H1105 GDSC2 3.8198 7.5472 1.6085 9.449
NCI-H1963 GDSC2 3.8263 10.3358 0.2259 17.3289
NCI-H2795 GDSC2 3.8278 12.6294 -0.9172 22.5637
DMS 273 GDSC2 3.8878 14.0633 -1.5847 24.9082
NCI-H1355 GDSC2 3.9118 6.9283 1.9836 6.8993
COR-L311 GDSC2 3.9293 10.0038 0.4727 15.7503
HOP-92 GDSC2 3.9296 7.8923 1.5213 9.7003
UMC-11 GDSC2 3.9521 13.0523 -1.0286 22.6668
IST-SL2 GDSC2 3.9852 6.7673 2.1158 5.9076
IA-LM GDSC2 4.0043 9.7699 0.6475 14.5989
RERF-LC-KJ GDSC2 4.0242 6.15 2.4417 3.8316
NCI-H2122 GDSC2 4.0428 8.7481 1.1837 11.4361
SBC-3 GDSC2 4.0934 7.8348 1.6717 8.3772
LXF 289 GDSC2 4.1068 18.9063 -3.8262 30.552
NCI-H2029 GDSC2 4.1297 8.3665 1.4371 9.7085
NCI-H1048 GDSC2 4.1349 13.0966 -0.9056 21.68
NCI-H1092 GDSC2 4.136 6.211 2.4864 3.3384
NCI-H2141 GDSC2 4.1456 6.1268 2.5321 3.0517
NCI-H2170 GDSC2 4.1522 7.6138 1.8225 7.3182
SBC-5 GDSC2 4.186 9.2286 1.0541 11.8293
SW1271 GDSC2 4.2063 8.9806 1.1916 10.9775
NCI-H1155 GDSC2 4.2163 13.1879 -0.887 21.3879
NCI-H524 GDSC2 4.228 7.8649 1.7541 7.5585
NCI-H1651 GDSC2 4.2722 13.4733 -0.9852 21.6386
NCI-H460 GDSC2 4.2791 8.543 1.4597 9.212
HCC366 GDSC2 4.2815 6.6156 2.3896 3.6264
LK-2 GDSC2 4.314 10.2539 0.644 13.8133
NCI-H1770 GDSC2 4.3341 8.4593 1.5401 8.6026
KNS-62 GDSC2 4.3381 8.888 1.3337 9.8209
COR-L321 GDSC2 4.341 7.4552 2.0305 5.6391
NCI-H1975 GDSC2 4.3468 6.7128 2.3855 3.5274
Calu-6 GDSC2 4.351 8.7066 1.4316 9.2104
PC-14 GDSC2 4.3605 8.0899 1.7382 7.3541
IST-SL1 GDSC2 4.4124 6.5046 2.5213 2.6396
LCLC-103H GDSC2 4.4567 8.8851 1.4199 9.0345
NCI-H146 GDSC2 4.459 8.5141 1.6015 7.9521
Ms-1 GDSC2 4.4695 8.2927 1.7157 7.2483
VMRC-LCD GDSC2 4.472 10.0773 0.8482 12.2931
HCC827 GDSC2 4.478 9.194 1.2847 9.7803
LC-2/ad GDSC2 4.4979 7.9326 1.9076 6.0449
NCI-H2804 GDSC2 4.5095 7.8824 1.9393 5.8331
RERF-LC-MS GDSC2 4.5386 10.0925 0.8893 11.9026
DMS 79 GDSC2 4.5553 6.8889 2.4313 2.9027
NCI-H2731 GDSC2 4.5903 11.2074 0.3798 14.5327
NCI-H2803 GDSC2 4.5932 8.1473 1.8687 6.0796
NCI-H2023 GDSC2 4.5938 6.4554 2.6452 1.7105
NCI-H2591 GDSC2 4.5991 8.2707 1.8139 6.3909
NCI-H647 GDSC2 4.6116 6.8673 2.4737 2.5808
NCI-H748 GDSC2 4.6311 9.6837 1.1551 10.1778
Lu-65 GDSC2 4.6369 7.6086 2.1502 4.3507
NCI-H82 GDSC2 4.6369 6.4707 2.6613 1.575
NCI-H841 GDSC2 4.6495 10.1873 0.9229 11.4524
NCI-H345 GDSC2 4.6598 5.493 3.0536 0.1101
NCI-H522 GDSC2 4.6652 7.5764 2.1827 4.1132
RERF-LC-Sq1 GDSC2 4.6656 10.4377 0.8122 12.0302
Lu-134-A GDSC2 4.6705 7.9617 2.0066 5.1187
LB647-SCLC GDSC2 4.673 8.3297 1.8346 6.1185
Lu-139 GDSC2 4.6976 7.4959 2.2394 3.7344
HCC78 GDSC2 4.698 10.785 0.6658 12.7541
NCI-H720 GDSC2 4.7203 6.3019 2.7731 0.9677
CPC-N GDSC2 4.7372 6.9274 2.5172 2.1661
NCI-H1734 GDSC2 4.7437 6.7938 2.5787 1.8454
NCI-H209 GDSC2 4.761 9.3117 1.4249 8.331
NCI-H196 GDSC2 4.7749 7.787 2.1527 4.0896
NCI-H2171 GDSC2 4.7961 8.1293 2.0076 4.8775
EBC-1 GDSC2 4.7971 8.5305 1.8205 5.9553
NCI-H1650 GDSC2 4.8017 9.1936 1.5089 7.7574
LOU-NH91 GDSC2 4.8182 6.8005 2.6145 1.5781
NCI-H2081 GDSC2 4.8453 7.8403 2.1707 3.8677
NCI-H838 GDSC2 4.8508 10.0464 1.1328 9.8125
NCI-H250 GDSC2 4.8777 9.6787 1.328 8.6417
NCI-H1792 GDSC2 4.9008 8.5904 1.8584 5.5383
LC-1/sq GDSC2 4.9207 13.4388 -0.4738 17.8429
NCI-H2227 GDSC2 4.9229 6.8944 2.6277 1.3974
NCI-H740 GDSC2 4.9237 13.5638 -0.5332 18.0984
NCI-H446 GDSC2 4.9259 7.8678 2.2057 3.5413
SW1573 GDSC2 4.9316 9.2253 1.5798 7.082
NCI-H226 GDSC2 4.9373 6.8193 2.6656 1.214
NCI-H513 GDSC2 4.9463 9.1796 1.611 6.8731
NCI-H2228 GDSC2 4.9469 11.179 0.6514 12.2537
NCI-H1437 GDSC2 4.9472 7.3968 2.4264 2.3406
Lu-165 GDSC2 4.97 11.5907 0.4675 13.1731
HARA [Human squamous cell lung carcinoma] GDSC2 4.9825 8.1576 2.1077 3.9877
CAL-12T GDSC2 5.0096 8.4697 1.9815 4.6439
SK-MES-1 GDSC2 5.035 7.3383 2.4977 1.8749
NCI-H1435 GDSC2 5.0441 7.6585 2.3649 2.5216
NCI-H1993 GDSC2 5.0674 6.9994 2.654 1.1358
NCI-H3255 GDSC2 5.0719 13.2768 -0.2831 16.621
HCC44 GDSC2 5.0794 7.5185 2.444 2.0799
NCI-H358 GDSC2 5.0842 7.7785 2.3344 2.6221
NCI-H1693 GDSC2 5.0889 9.4882 1.5576 6.8995
HOP-62 GDSC2 5.0896 12.0734 0.3175 13.6712
NCI-H1869 GDSC2 5.0993 12.1854 0.2699 13.8905
NCI-H2369 GDSC2 5.1086 7.0667 2.6461 1.13
NCI-H2172 GDSC2 5.1246 11.1462 0.7912 11.1058
NCI-H1299 GDSC2 5.129 9.7646 1.4533 7.4135
NCI-H290 GDSC2 5.1434 7.0958 2.6506 1.08
ChaGo-K-1 GDSC2 5.1583 10.1645 1.2834 8.3142
COR-L23 GDSC2 5.1596 6.6766 2.8197 0.4677
NCI-H2087 GDSC2 5.2162 7.6052 2.477 1.7604
NCI-H2595 GDSC2 5.2207 7.5807 2.4895 1.6985
NCI-H1793 GDSC2 5.2222 14.9325 -0.9859 19.2955
NCI-H1836 GDSC2 5.2231 6.7731 2.8095 0.4627
NCI-H3122 GDSC2 5.262 11.1307 0.8921 10.2653
NCI-H2818 GDSC2 5.2669 12.5395 0.2162 13.7805
SBC-1 GDSC2 5.3073 7.124 2.7122 0.7195
NCI-H292 GDSC2 5.3244 22.3694 -4.5888 29.4752
NCI-H2810 GDSC2 5.3335 8.0216 2.3612 2.1674
NCI-H1563 GDSC2 5.3455 11.6119 0.718 11.0245
NCI-H2373 GDSC2 5.3651 11.3929 0.8359 10.3533
NCI-H1568 GDSC2 5.4069 12.4993 0.3332 12.8862
NCI-H2722 GDSC2 5.4991 13.2229 0.0475 14.0945
NCI-H2405 GDSC2 5.4995 14.5331 -0.5888 17.0042
COR-L32 GDSC2 5.5238 7.5573 2.6385 0.8226
NCI-H661 GDSC2 5.5338 9.4043 1.8663 4.4138
COR-L303 GDSC2 5.5352 7.116 2.8068 0.3256
LCLC-97TM1 GDSC2 5.5354 8.6612 2.1932 2.7304
SK-LU-1 GDSC2 5.5715 7.3175 2.748 0.4568
NCI-H2461 GDSC2 5.6532 8.2204 2.4352 1.4945
NCI-H2869 GDSC2 5.6861 10.4492 1.4827 6.2282
Lu-135 GDSC2 5.6867 8.3823 2.3854 1.6718
NCI-H1915 GDSC2 5.7246 7.2689 2.8233 0.2274
NCI-H520 GDSC2 5.7752 13.2294 0.2335 12.6022
DMS 114 GDSC2 5.7821 16.0904 -1.1463 18.6704
EMC-BAC-1 GDSC2 5.8045 9.3145 2.0541 3.0675
NCI-H2291 GDSC2 5.8257 7.648 2.727 0.397
NCI-H1876 GDSC2 5.8858 8.0302 2.6108 0.6835
NCI-H1755 GDSC2 5.8927 7.643 2.7541 0.311
NCI-H441 GDSC2 5.9235 7.8489 2.6923 0.4404
NCI-H596 GDSC2 5.9297 7.4808 2.8239 0.1741
EPLC-272H GDSC2 5.9371 7.7909 2.7183 0.3732
NCI-H650 GDSC2 5.9929 8.0697 2.6392 0.546
NCI-H1666 GDSC2 6.1133 14.0197 0.0823 12.6467
NCI-H2085 GDSC2 6.1328 8.2211 2.6388 0.483
NCI-H2110 GDSC2 6.1489 8.9077 2.3872 1.2604
NCI-H211 GDSC2 6.1596 8.4111 2.58 0.6254
NCI-H727 GDSC2 6.1837 16.6064 -1.1129 17.6855
NCI-H1781 GDSC2 6.2467 16.3454 -0.9429 16.8799
NCI-H2030 GDSC2 6.3207 7.8818 2.8242 0.104
COR-L105 GDSC2 6.3235 18.6924 -2.0282 20.7003
HCC15 GDSC2 6.4298 17.5518 -1.399 18.2716
HCC33 GDSC2 6.5185 16.5691 -0.8642 16.0119
NCI-H322M GDSC2 6.7644 8.7948 2.6703 0.2209
A-549 GDSC2 8.1596 22.032 -2.3735 18.3817
⏷ Show the Full List of 166 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 5.2533 7.5053 2.5364 1.4547
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OE19 GDSC2 3.4183 4.9519 2.5858 4.3881
TE-6 GDSC2 3.5127 6.2022 2.0376 7.5909
TE-4 GDSC2 3.6623 7.4384 1.54 10.2877
KYSE-270 GDSC2 4.2327 9.1971 1.1045 11.4205
OE21 GDSC2 4.2521 7.3635 2.014 5.9292
EC-GI-10 GDSC2 4.3004 8.6067 1.444 9.2559
TE-9 GDSC2 4.5119 7.651 2.0506 5.17
OE33 GDSC2 4.6123 7.8712 2.0118 5.2004
COLO 680N GDSC2 4.8366 7.2609 2.4255 2.5004
TE-10 GDSC2 5.009 7.1577 2.5606 1.6089
TE-5 GDSC2 5.0685 8.6286 1.9443 4.7503
TE-1 GDSC2 5.1067 12.0433 0.3442 13.4964
KYSE-450 GDSC2 5.1517 12.3653 0.2196 14.0236
KYSE-70 GDSC2 5.1609 10.5917 1.0818 9.4349
TE-11 GDSC2 5.3512 7.7566 2.4806 1.5986
TE-8 GDSC2 5.4059 8.6153 2.1439 3.1503
KYSE-180 GDSC2 5.5833 15.348 -0.9265 18.2334
KYSE-410 GDSC2 5.6698 10.2172 1.5788 5.737
KYSE-520 GDSC2 5.7575 15.6004 -0.9249 17.8432
KYSE-140 GDSC2 6.0353 8.7006 2.418 1.2348
TE-15 GDSC2 6.276 8.5896 2.5607 0.6204
KYSE-510 GDSC2 8.04 19.4367 -1.2248 14.631
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OV-90 GDSC2 2.9445 5.7552 1.778 10.9235
OVCAR-3 GDSC2 3.2769 7.4727 1.2089 13.4037
OAW28 GDSC2 3.71 7.544 1.5249 10.2521
JHOS-4 GDSC2 3.776 7.2378 1.7283 8.8231
OVK18 GDSC2 3.8824 8.6393 1.1146 12.2612
Caov-3 GDSC2 3.9331 7.2284 1.8517 7.6625
A2780 GDSC2 3.935 8.0889 1.4281 10.2522
OVISE GDSC2 4.1257 7.9268 1.6502 8.4299
TOV-112D GDSC2 4.1847 7.6346 1.8355 7.1639
OVCAR-4 GDSC2 4.3802 9.6006 1.015 11.5735
OV56 GDSC2 4.6252 9.8566 1.0667 10.6965
TOV-21G GDSC2 4.8466 6.6197 2.7037 1.1402
TYK-nu GDSC2 4.8909 14.0193 -0.7821 19.2457
JHOS-2 GDSC2 4.9719 10.8563 0.8255 11.2558
IGROV-1 GDSC2 4.9905 8.3217 2.0378 4.3622
OVTOKO GDSC2 4.9968 13.6262 -0.5097 17.82
EFO-27 GDSC2 5.1687 9.8428 1.4422 7.3988
ES-2 GDSC2 5.2559 6.8822 2.7823 0.5254
Kuramochi GDSC2 5.2786 13.5804 -0.2822 16.1381
OVCAR-8 GDSC2 5.2968 7.5777 2.5277 1.4487
SK-OV-3 GDSC2 5.3277 7.3827 2.6205 1.0393
EFO-21 GDSC2 5.4139 8.5103 2.1939 2.886
OVCAR-5 GDSC2 5.7883 7.8953 2.6213 0.7082
DOV13 GDSC2 6.0654 7.7373 2.7843 0.2047
OAW42 GDSC2 7.9363 25.4939 -4.1936 23.7355
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HPAC GDSC2 2.2923 5.041 1.5038 14.8919
HuP-T4 GDSC2 3.3523 10.9705 -0.4771 22.0701
Capan-1 GDSC2 3.5308 6.4469 1.9299 8.2186
BxPC-3 GDSC2 3.7658 8.1615 1.2614 11.7012
SU.86.86 GDSC2 3.9801 7.082 1.9582 6.891
PaTu 8988t GDSC2 4.0403 14.4455 -1.653 24.7366
PaTu 8902 GDSC2 4.1084 7.0377 2.0717 5.8963
MZ-PC-1 GDSC2 4.1359 8.4496 1.4008 9.9108
HPAF-II GDSC2 4.36 9.5549 1.0225 11.5795
SUIT-2 GDSC2 4.5409 9.4764 1.1919 10.1734
Panc 02.03 GDSC2 4.5516 7.6992 2.0536 5.0741
HuP-T3 GDSC2 4.6665 13.8368 -0.8613 20.1269
PSN1 GDSC2 4.6748 9.0164 1.508 8.0318
Panc 08.13 GDSC2 4.9896 10.8453 0.8431 11.1199
AsPC-1 GDSC2 4.9999 11.5026 0.5316 12.7687
QGP-1 GDSC2 5.0263 9.6545 1.4385 7.7015
DAN-G GDSC2 5.2012 12.1464 0.3608 13.1992
KP-2 GDSC2 5.3078 10.9471 1.0103 9.5256
MIA PaCa-2 GDSC2 5.4492 12.9184 0.16 13.6558
Capan-2 GDSC2 5.4544 8.8931 2.0486 3.5728
YAPC GDSC2 5.5361 20.67 -3.583 26.7998
Panc 10.05 GDSC2 5.5526 7.4666 2.6851 0.6504
KP-1N GDSC2 5.6206 7.9523 2.5272 1.1555
KP-4 GDSC2 5.6231 14.5816 -0.5245 16.4502
CFPAC-1 GDSC2 6.0057 7.8521 2.7224 0.339
KP-3 GDSC2 6.0342 12.9986 0.5142 10.6874
PL4 GDSC2 6.1823 8.0266 2.7263 0.2745
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC2 4.4015 9.0803 1.2854 9.9551
MSTO-211H GDSC2 5.0616 8.9172 1.807 5.5349
IST-Mes1 GDSC2 5.0981 11.9122 0.402 13.22
NCI-H2052 GDSC2 5.5116 11.4376 0.9117 9.6478
NCI-H28 GDSC2 5.5637 7.7409 2.5848 0.9848
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC2 3.4016 5.6508 2.2232 6.7275
VCaP GDSC2 4.0931 6.869 2.1427 5.4971
NCI-H660 GDSC2 4.7949 6.3758 2.7782 0.8765
LNCaP clone FGC GDSC2 5.2264 8.7962 1.9619 4.3877
PC-3 GDSC2 5.4266 9.7087 1.6654 5.6785
22Rv1 GDSC2 5.7732 8.685 2.303 1.9415
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 5.0377 9.514 1.5124 7.2571
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RVH-421 GDSC2 3.1596 9.9242 -0.1155 20.9864
SK-MEL-28 GDSC2 3.6264 15.7861 -2.6582 28.9198
DJM-1 GDSC2 3.7133 9.0062 0.799 14.5459
LB2518-MEL GDSC2 3.8466 8.5048 1.1537 12.1257
A2058 GDSC2 3.8484 5.4394 2.6633 2.8649
SK-MEL-5 GDSC2 3.8742 6.3355 2.2469 5.3582
VMRC-MELG GDSC2 3.9741 5.8665 2.5436 3.3234
RPMI-7951 GDSC2 3.9892 5.9182 2.529 3.3797
IGR-1 GDSC2 4.0231 9.8575 0.6185 14.708
G-361 GDSC2 4.1667 6.6806 2.2837 4.4841
LB373-MEL-D GDSC2 4.1797 7.8277 1.7378 7.7696
CHL-1 GDSC2 4.1966 8.2731 1.532 8.9754
G-mel GDSC2 4.2044 6.6554 2.3208 4.1845
UACC-62 GDSC2 4.4491 6.8375 2.3911 3.3096
COLO 783 GDSC2 4.5027 6.3496 2.642 1.8511
SK-MEL-30 GDSC2 4.5072 5.6535 2.9341 0.5138
WM35 GDSC2 4.5148 8.3245 1.7314 7.0571
M14 GDSC2 4.6168 8.2629 1.8294 6.2631
Hs 940.T GDSC2 4.6433 8.8254 1.5783 7.6868
Hs 938.T GDSC2 4.7236 7.6957 2.1635 4.1186
A101D GDSC2 4.7573 7.7915 2.1399 4.1927
MZ-MEL-2 GDSC2 4.761 10.1568 1.0168 10.6683
GAK GDSC2 4.771 10.9046 0.6599 12.6141
A-388 GDSC2 4.8136 8.5259 1.8332 5.8494
WT2-iPS GDSC2 4.8636 6.8356 2.6227 1.4865
A-375 GDSC2 4.9075 10.5833 0.9127 10.9196
SK-MEL-2 GDSC2 4.9548 6.2248 2.9044 0.3342
WM278 GDSC2 5.0013 14.433 -0.9037 19.4834
CP66-MEL GDSC2 5.0119 6.2865 2.9043 0.3079
SK-MEL-31 GDSC2 5.0121 13.1625 -0.2707 16.7048
Mel Ho GDSC2 5.015 6.3244 2.8917 0.3392
451Lu GDSC2 5.0388 14.0726 -0.6983 18.537
A-431 GDSC2 5.0537 7.8489 2.2867 2.9118
WM115 GDSC2 5.058 6.2008 2.9523 0.1821
COLO 829 GDSC2 5.1032 11.8753 0.4234 13.0981
SK-MEL-3 GDSC2 5.1413 6.3941 2.9151 0.2307
SK-MEL-24 GDSC2 5.2544 11.7222 0.6029 11.8279
COLO 792 GDSC2 5.2825 15.9327 -1.4335 20.8802
IPC-298 GDSC2 5.2857 6.56 2.9102 0.1937
MMAc-SF GDSC2 5.3037 9.7529 1.5697 6.4272
CP50-MEL-B GDSC2 5.3525 9.9374 1.5144 6.646
WM793 GDSC2 5.3736 6.8186 2.8517 0.2852
LOX-IMVI GDSC2 5.4216 6.7518 2.8929 0.1865
UACC-257 GDSC2 5.4735 6.7471 2.9131 0.1404
MZ-MEL-7 GDSC2 5.6166 7.3876 2.7402 0.4563
COLO 800 GDSC2 5.7243 7.1846 2.8524 0.1772
WM1552C GDSC2 5.7772 7.5596 2.7402 0.3854
COLO 679 GDSC2 5.8227 8.4115 2.4368 1.3367
IGR-37 GDSC2 5.9221 15.6251 -0.8205 17.0604
HMV-II GDSC2 5.9656 7.7632 2.7388 0.3181
Mel JuSo GDSC2 6.0623 19.4616 -2.5936 23.0194
SH-4 GDSC2 6.3151 8.3316 2.6684 0.3464
HT-144 GDSC2 6.3469 16.7107 -1.0499 17.1018
EquiPSC Line K2 GDSC2 5.4543 9.2326 1.8976 4.3706
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 3 5.3079 2.0493 9.0442
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1080 GDSC2 2.8537 5.2564 1.9413 10.2037
TE 441.T GDSC2 3.6413 10.7492 -0.129 19.615
KYM-1 GDSC2 3.6625 8.4094 1.0562 13.2025
Rh30 GDSC2 4.1182 7.1118 2.0425 6.0525
A-204 GDSC2 4.3532 9.8134 0.8904 12.3474
Rh41 GDSC2 4.3892 8.5257 1.5469 8.4354
EW-8 GDSC2 4.4191 8.1638 1.7431 7.1951
VA-ES-BJ GDSC2 4.687 10.5557 0.77 12.2122
RKN GDSC2 4.7341 9.1497 1.4843 8.0431
MES-SA GDSC2 4.9688 11.0116 0.7481 11.6835
STS-0421 GDSC2 5.0195 7.6061 2.3744 2.5065
SK-UT-1 GDSC2 5.0861 10.8197 0.9219 10.4768
SW982 GDSC2 5.1468 7.2208 2.6017 1.2797
SW684 GDSC2 5.1645 6.6033 2.8487 0.3828
RD GDSC2 5.2706 10.2703 1.3066 7.9609
SW872 GDSC2 5.2955 17.4213 -2.1581 23.3392
G-401 GDSC2 5.3742 14.4182 -0.6227 17.4331
SK-LMS-1 GDSC2 5.6663 7.495 2.7205 0.485
G-402 GDSC2 6.3045 12.8328 0.7626 8.9298
GCT GDSC2 6.4702 18.7248 -1.9396 20.1058
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KATO III GDSC2 2.9101 6.5686 1.3438 13.7222
MKN45 GDSC2 3.6467 7.6007 1.4468 10.9018
IM95 GDSC2 3.7458 8.606 1.0243 13.1592
ECC12 GDSC2 3.7852 8.9553 0.8814 13.878
SNU-5 GDSC2 3.8819 7.3819 1.7376 8.4945
AGS GDSC2 3.9062 10.0525 0.4303 16.0396
MKN1 GDSC2 4.0168 9.6167 0.7332 14.091
SNU-1 GDSC2 4.0832 8.9116 1.1334 11.6284
23132/87 GDSC2 4.1655 10.0224 0.6461 14.1823
TMK-1 GDSC2 4.1917 8.812 1.2637 10.589
OCUM-1 GDSC2 4.3286 7.1842 2.1516 4.9408
NCI-N87 GDSC2 4.3778 8.8383 1.3865 9.4148
Hs 746.T GDSC2 4.4958 15.958 -2.0464 24.8774
SCH GDSC2 4.6592 6.2694 2.7571 1.0995
MKN28 GDSC2 4.7796 8.517 1.8155 6.0183
RF-48 GDSC2 4.8322 7.7417 2.2077 3.6834
GCIY GDSC2 5.1892 9.0917 1.8048 5.319
ECC10 GDSC2 5.247 7.177 2.6653 0.9336
SK-GT-2 GDSC2 5.6752 8.5257 2.321 1.965
MKN7 GDSC2 5.7876 8.0826 2.5498 0.9451
NUGC-3 GDSC2 5.8186 7.9729 2.6046 0.7424
NUGC-4 GDSC2 5.8486 7.8042 2.6793 0.5078
HGC-27 GDSC2 6.1238 14.5571 -0.167 13.79
RERF-GC-1B GDSC2 6.5572 8.8234 2.5849 0.4399
SNG-M GDSC2 4.3637 13.6453 -0.9993 21.4565
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HTC-C3 GDSC2 2.1512 6.2303 0.8054 19.5359
BHT-101 GDSC2 4.042 6.2357 2.4127 3.9692
KMH-2 GDSC2 4.1402 8.7424 1.2597 10.7404
ASH-3 GDSC2 4.2771 11.52 -0.0109 17.2994
CAL-62 GDSC2 4.4961 9.7531 1.0246 11.2393
ML-1 [Human leukemia] GDSC2 4.5279 11.0088 0.4314 14.4168
8305C GDSC2 4.6946 7.6733 2.156 4.2128
FTC-133 GDSC2 4.8482 9.9878 1.1593 9.6683
IHH-4 GDSC2 5.4198 6.9882 2.8085 0.3694
K5 GDSC2 5.4644 7.4521 2.6535 0.8125
8505C GDSC2 5.6233 7.9185 2.5417 1.0981
B-CPAP GDSC2 5.6517 7.2886 2.7894 0.3208
TT2609-C02 GDSC2 5.8983 7.819 2.6934 0.4487
WRO GDSC2 5.9935 7.7223 2.7635 0.2604
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-4 GDSC2 0.2835 2.2657 0.2233 30.7938
BICR 78 GDSC2 2.098 4.0396 1.7394 14.2626
Ca9-22 GDSC2 2.5855 5.607 1.5197 13.7327
LB771-HNC GDSC2 2.7033 7.5225 0.6862 18.2702
UPCI-SCC-090 GDSC2 2.8569 11.4144 -1.1181 26.2248
BHY GDSC2 3.1488 9.1266 0.2741 19.0702
Detroit 562 GDSC2 3.8103 5.8965 2.4155 4.4652
PCI-15A GDSC2 3.8746 7.6838 1.5827 9.4659
SCC-9 GDSC2 3.8843 7.6123 1.6255 9.1784
DOK GDSC2 4.1825 9.1198 1.1052 11.5411
PCI-06A GDSC2 4.2424 6.764 2.2943 4.2654
BB49-HNC GDSC2 4.2478 10.6404 0.4027 15.2768
KOSC-2 GDSC2 4.3312 7.2168 2.1378 5.0174
CAL-27 GDSC2 4.4669 11.4603 0.1631 15.9492
PE/CA-PJ15 GDSC2 4.4778 8.1027 1.8127 6.6519
OSC-20 GDSC2 4.5958 7.969 1.9549 5.5664
HSC-2 GDSC2 4.6024 8.7899 1.5675 7.8386
HSC-3 GDSC2 4.6255 9.5633 1.2096 9.8772
SAS GDSC2 4.6522 7.6339 2.148 4.3355
BB30-HNC GDSC2 4.705 15.971 -1.8902 23.8524
JHU-029 GDSC2 4.7223 7.4577 2.2717 3.5114
KON GDSC2 4.7519 7.8741 2.0984 4.4382
HO-1-N-1 GDSC2 4.8186 9.0139 1.6058 7.1597
SCC-25 GDSC2 4.9192 11.2542 0.5953 12.6169
JHU-011 GDSC2 4.983 7.3175 2.4797 2.0271
BICR 31 GDSC2 5.0121 12.6322 -0.0108 15.478
CAL-33 GDSC2 5.0773 17.0949 -2.162 23.852
SAT [Human HNSCC] GDSC2 5.2975 13.2135 -0.0898 15.1987
PCI-04B GDSC2 5.3063 12.1682 0.4235 12.6462
FaDu GDSC2 5.3257 9.5861 1.6605 5.882
OSC-19 GDSC2 5.3949 6.955 2.8109 0.3744
JHU-022 GDSC2 5.507 8.136 2.3999 1.7921
SKN-3 GDSC2 5.5592 12.1761 0.5919 11.2393
BICR 10 GDSC2 5.6325 18.2735 -2.3264 23.1203
NCI-H3118 GDSC2 5.7 12.4301 0.5647 11.0918
SCC-4 GDSC2 5.775 14.7357 -0.4924 15.9793
BICR 22 GDSC2 5.8198 7.1292 2.9043 0.0898
SCC-15 GDSC2 6.0514 17.3586 -1.5722 19.6894
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-4 GDSC2 4.0569 8.444 1.3446 10.4441
647V GDSC2 4.1712 6.4361 2.403 3.7621
BFTC-905 GDSC2 4.2042 8.9439 1.208 10.8863
J82 GDSC2 4.2714 9.6454 0.9124 12.4263
TCCSUP GDSC2 4.3031 6.4622 2.4746 3.0931
CAL-29 GDSC2 4.4879 6.6318 2.5081 2.5891
5637 GDSC2 4.5215 6.6946 2.4993 2.5833
SW1710 GDSC2 4.54 8.6424 1.5957 7.8079
639V GDSC2 4.7341 11.6165 0.2846 14.6732
KU-19-19 GDSC2 5.0164 8.4357 2.0012 4.5222
RT-112 GDSC2 5.0732 10.3235 1.1511 9.232
HT-1197 GDSC2 5.2244 12.4257 0.2415 13.7495
SW780 GDSC2 5.2326 17.2294 -2.1108 23.3305
T24 GDSC2 5.4129 12.2913 0.4375 12.3433
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa GDSC2 2.0365 6.229 0.6953 20.5866
JEG-3 GDSC2 2.526 4.4878 1.9913 11.0655
DSH1 GDSC2 3.497 10.3458 -0.0452 19.629
SW962 GDSC2 3.6703 5.5704 2.4732 4.4421
SKG-IIIa GDSC2 3.6709 7.4282 1.5519 10.1917
OVCA420 GDSC2 3.822 9.1312 0.8228 14.1113
PA-1 GDSC2 3.9216 7.651 1.6345 9.0284
OV17R GDSC2 3.926 7.1119 1.9038 7.358
C-33 A GDSC2 3.9283 7.6333 1.6484 8.9264
PWR-1E GDSC2 4.0465 7.3473 1.8765 7.2361
C-4-I GDSC2 4.0512 8.2773 1.4226 9.9903
HEC-1 GDSC2 4.1016 8.7392 1.2325 10.9985
OMC-1 [Human cervical carcinoma] GDSC2 4.1096 8.1854 1.5113 9.3105
ACC-OV7 GDSC2 4.2259 9.5821 0.9096 12.557
ME-180 GDSC2 4.327 8.8471 1.3456 9.777
UWB1.289 GDSC2 4.4258 9.506 1.0947 11.006
HT-3 GDSC2 4.4698 9.9903 0.8893 12.0682
DoTc2 4510 GDSC2 4.4817 8.7905 1.4836 8.6014
SiSo GDSC2 4.6226 12.3464 -0.1575 17.1228
MS751 GDSC2 4.7972 11.0437 0.6108 12.8165
SW756 GDSC2 4.9384 11.3667 0.5541 12.7906
SKN GDSC2 5.0045 7.7204 2.3161 2.8297
OVMIU GDSC2 5.0075 12.3885 0.1051 14.9241
HEY GDSC2 5.0105 14.4785 -0.9192 19.5246
SW954 GDSC2 5.1534 8.3491 2.1207 3.643
TC-YIK GDSC2 5.1643 7.7691 2.3811 2.2809
NEC8 GDSC2 5.1935 6.5419 2.8822 0.285
LB831-BLC GDSC2 5.2316 12.3709 0.2732 13.5744
JHOS-3 GDSC2 5.4824 10.8726 1.1594 8.362
CAL-39 GDSC2 5.5141 7.5715 2.6289 0.8632
JAR GDSC2 5.6461 7.0199 2.881 0.1507
OVCA433 GDSC2 5.7153 7.9541 2.5681 0.9324
PEO1 GDSC2 5.7812 8.0139 2.5734 0.8686
Ca Ski GDSC2 6.0459 8.6526 2.4413 1.1416
BPH-1 GDSC2 6.4027 8.76 2.5483 0.5928
SiHa GDSC2 6.763 18.5952 -1.672 18.5979
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8574).
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2730).
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2724).