Details of the Drug

General Information of Drug (ID: DMKETFV)

Drug Name
SMER3
Synonyms
67200-34-4; SMER 3; 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one; 9H-Indeno[1,2-b][1,2,5]oxadiazolo[3,4-E]pyrazin-9-one; SMER-3; C11H4N4O2; LSM-42773; 9H-Indeno-[1,2-e]-[1,2,5]-oxadiazolo-[3,4-b]-pyrazin-9-one; indeno[2,3-b]1,2,5-oxadiazolo[3,4-e]pyrazin-5-one; 2-Oxa-1,3,4,10-tetraaza-cyclopenta[b]fluoren-9-one; SMER3(SMER 3); Oprea1_175199; Oprea1_783821; SCHEMBL7984580; CHEMBL3589013; ZINC27763; AOB5567; DTXSID40340952; CHEBI:131171; BDBM188214; HMS1607O01; BCP14360; 2188AH; MFCD00451458; SBB000632; STK120842; SMER3, >=98% (HPLC); AKOS000479457; MCULE-1070513713; AS-55891; ST000573; DB-073845; FT-0701471; Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one; Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one,; US9073941, 28; US9073941, 30; SR-01000388225; SR-01000388225-1; Q27224946; 9H-Indeno[1,2-b][1,2,5]oxadiazolo[3,4-E]pyrazin-9-one #
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Preclinical [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C11H4N4O2
Canonical SMILES
C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O
InChI
1S/C11H4N4O2/c16-9-6-4-2-1-3-5(6)7-8(9)13-11-10(12-7)14-17-15-11/h1-4H
InChIKey
SFSSAKVWCKFRHE-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
568763
ChEBI ID
CHEBI:131171
CAS Number
67200-34-4
TTD ID
DHD79B

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 119 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -1.2002 4.5244 -1.5048 48.4494
MEC1 CTRP2 0.8385 1.7135 0.8385 34.6825
JM1 CTRP2 -0.4543 1.3408 -0.4548 43.2967
EM-2 CTRP2 -2.8365 -2.0236 -2.8365 59.1657
ALL-SIL CTRP2 -2.4075 -1.494 -2.4075 56.308
HT CTRP2 -2.3006 -1.875 -2.3006 55.5954
TALL-1 [Human adult T-ALL] CTRP2 -2.2143 -0.3922 -2.2143 55.019
RS4;11 CTRP2 -2.1747 -0.6841 -2.1748 54.7569
Peer CTRP2 -2.1572 -1.1481 -2.1572 54.6405
WSU-DLCL2 CTRP2 -2.1136 -0.2274 -2.1137 54.348
SU-DHL-6 CTRP2 -2.0718 -0.8554 -2.0718 54.071
NB4 CTRP2 -1.9262 -1.1466 -1.9262 53.1014
SUP-T11 CTRP2 -1.8803 -0.8132 -1.8803 52.7956
SU-DHL-8 CTRP2 -1.7398 -0.6261 -1.7398 48.4237
DEL CTRP2 -1.7044 -1.073 -1.7044 51.6233
KMS-11 CTRP2 -1.671 -0.4451 -1.671 51.4013
KMS-34 CTRP2 -1.619 -0.896 -1.619 51.0549
NU-DUL-1 CTRP2 -1.5179 0.1523 -1.518 50.3812
Kasumi-2 CTRP2 -1.4847 0.3266 -1.4849 50.16
MV4-11 CTRP2 -1.4672 0.0319 -1.4672 50.0435
KMS-28BM CTRP2 -1.4627 1.5903 -1.4752 50.0134
MOLT-13 CTRP2 -1.4592 -0.2896 -1.4592 49.9899
Daudi CTRP2 -1.4563 -0.8471 -1.4563 49.9708
EoL-1 CTRP2 -1.4486 -0.2042 -1.4486 49.9196
ST486 CTRP2 -1.4204 -0.7814 -1.4204 49.7316
MHH-CALL-4 CTRP2 -1.4059 3.2668 -1.5302 49.6555
ME1 CTRP2 -1.3965 0.868 -1.398 49.573
Ri-1 CTRP2 -1.3693 0.8933 -1.3708 49.392
NALM-6 CTRP2 -1.3437 -0.0328 -1.3437 49.2205
MOLT-16 CTRP2 -1.3067 -0.5115 -1.3067 48.9743
SR CTRP2 -1.2968 -0.5296 -1.2968 48.9079
MOLP-8 CTRP2 -1.286 -0.5793 -1.286 48.8363
OCI-Ly3 CTRP2 -1.2591 -0.4488 -1.2591 48.657
P31/FUJ CTRP2 -1.2363 0.6183 -1.2366 48.5054
KMS-20 CTRP2 -1.1803 0.6814 -1.1806 48.1326
SKM-1 CTRP2 -1.1038 0.1712 -1.1038 47.6223
MOLM-13 CTRP2 -0.9659 0.7646 -0.9661 46.704
SK-MM-2 CTRP2 -0.9645 0.5019 -0.9645 46.6941
Mino CTRP2 -0.9416 0.0725 -0.9416 46.5415
HPB-ALL CTRP2 -0.9288 0.4653 -0.9289 46.4568
SUP-T1 CTRP2 -0.8661 0.0781 -0.8661 46.0385
PL21 CTRP2 -0.8544 0.3251 -0.8544 45.9605
NCO2 CTRP2 -0.8142 0.8082 -0.8143 45.6931
DND-41 CTRP2 -0.7772 1.0076 -0.7776 45.4475
SU-DHL-4 CTRP2 -0.7711 0.2495 -0.7711 45.4057
JVM-2 CTRP2 -0.7522 1.614 -0.7561 45.2896
P12-Ichikawa CTRP2 -0.75 0.0367 -0.75 45.2655
M-07e CTRP2 -0.7272 0.0312 -0.7272 45.1136
BV-173 CTRP2 -0.6875 0.809 -0.6876 44.8492
Ku812 CTRP2 -0.6826 1.0734 -0.6829 44.8172
NU-DHL-1 CTRP2 -0.6549 1.1687 -0.6554 44.6329
HL-60 CTRP2 -0.6363 0.0665 -0.6363 44.5075
KMS-26 CTRP2 -0.6224 0.0702 -0.6224 44.4154
KMS-21-BM CTRP2 -0.5862 0.6574 -0.5863 44.1743
SU-DHL-1 CTRP2 -0.5797 -0.0965 -0.5797 44.1304
THP-1 CTRP2 -0.5289 0.6819 -0.5289 43.7921
PF-382 CTRP2 -0.5254 0.3461 -0.5254 43.7692
SUP-HD1 CTRP2 -0.4541 1.9106 -0.4593 43.3086
SET-2 CTRP2 -0.4186 1.0798 -0.4187 43.058
RPMI-8402 CTRP2 -0.3719 0.5774 -0.3719 42.7464
L-540 CTRP2 -0.3643 0.6667 -0.3643 42.6957
SIG-M5 CTRP2 -0.3402 0.4008 -0.3402 42.5353
KE-37 CTRP2 -0.2935 0.3661 -0.2935 42.2243
SEM CTRP2 -0.2914 0.9993 -0.2915 42.2104
L-363 CTRP2 -0.2877 0.9387 -0.2878 42.1857
RPMI-8226 CTRP2 -0.2009 1.3537 -0.2011 41.6079
L-428 CTRP2 -0.1603 1.0851 -0.1603 41.3364
KE-97 CTRP2 -0.1495 0.8457 -0.1495 41.2645
RL CTRP2 -0.1475 1.3872 -0.1477 41.2517
MHH-CALL-3 CTRP2 -0.1297 4.2052 -0.2951 41.547
OCI-AML-2 CTRP2 -0.0358 1.3818 -0.0359 40.5073
SU-DHL-10 CTRP2 -0.0326 1.5699 -0.034 36.2429
LAMA-84 CTRP2 -0.0156 1.3753 -0.0157 40.3728
JURL-MK1 CTRP2 -0.0118 0.8823 -0.0118 40.3471
F-36P CTRP2 0.0589 1.6152 0.0586 39.8774
KMS-18 CTRP2 0.0745 1.1023 0.0745 39.7722
HuT 78 CTRP2 0.1028 1.5041 0.1027 39.5839
MOLM-6 CTRP2 0.1712 1.6171 0.171 39.1288
CML-T1 CTRP2 0.1772 0.9383 0.1772 39.088
NCI-H929 CTRP2 0.2029 1.2566 0.2029 38.9169
KMS-12-BM CTRP2 0.221 1.1604 0.221 38.7963
MC116 CTRP2 0.2646 1.5408 0.2645 38.5063
KO52 CTRP2 0.3233 1.5623 0.3232 38.1151
Mono-Mac-1 CTRP2 0.3739 3.1632 0.3451 37.8685
U266B1 CTRP2 0.5023 2.1219 0.5015 36.9248
MOTN-1 CTRP2 0.5266 2.1352 0.5258 36.763
MOLP-2 CTRP2 0.5664 2.3959 0.5641 36.5029
U-937 CTRP2 0.5854 1.2899 0.5854 36.3688
SUP-B15 CTRP2 0.7187 2.3705 0.7174 35.485
Ci-1 CTRP2 0.7882 1.26 0.7882 35.0178
HDLM-2 CTRP2 0.8613 2.3332 0.8607 34.5325
AML-193 CTRP2 0.9211 1.9863 0.9211 34.1322
JeKo-1 CTRP2 0.9223 1.8986 0.9223 34.124
K-562 CTRP2 1.1186 2.3169 1.1184 32.8171
KYO-1 CTRP2 1.3009 2.5586 1.3007 31.6026
KMS-27 CTRP2 1.5359 2.67 1.5357 30.0368
OCI-M1 CTRP2 1.9511 3.0704 1.9508 27.2711
JJN-3 CTRP2 2.1284 3.1691 2.1281 26.09
Karpas-620 CTRP2 2.4515 4.4728 2.4152 24.0586
OCI-AML-5 CTRP2 2.5243 3.184 2.5243 23.4513
Reh CTRP2 2.5918 3.2199 2.496 4.2699
Raji CTRP2 3.024 4.0713 2.5196 2.8716
HEL CTRP2 3.6061 8.489 2.4696 20.4571
P3HR-1 CTRP2 3.788 14.147 -0.0128 28.1457
Ki-JK CTRP2 4.0412 9.8079 2.3124 19.9134
RCH-ACV CTRP2 4.966 10.2988 2.963 15.1439
Jurkat CTRP2 5.4166 11.247 2.903 14.3901
Mono-Mac-6 CTRP2 5.4365 16.8785 0.1128 24.0141
MOLM-16 CTRP2 5.9656 12.3137 2.8439 13.4964
MM1.S CTRP2 6.0009 11.3204 3.3701 11.2921
REC-1 CTRP2 6.0141 11.9686 3.057 12.544
EHEB CTRP2 6.1485 12.8288 2.7386 13.556
KMM-1 CTRP2 6.5863 15.5159 1.7523 16.4387
GDM-1 CTRP2 7.0326 10.6443 4.5069 4.7854
JVM-3 CTRP2 7.4346 15.8951 2.2242 13.2059
AMO1 CTRP2 7.5271 9.111 5.5001 0.5778
KHM-1B CTRP2 7.6848 15.6237 2.5436 11.5967
KCL-22 CTRP2 8.4322 14.5312 3.5878 6.4892
KM-H2 CTRP2 8.9214 16.4905 2.9804 8.1424
⏷ Show the Full List of 119 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 -1.0786 -0.1306 -1.0786 47.4545
TE15 CTRP2 2.3678 3.3541 2.3676 24.4946
TE-10 CTRP2 0.1279 1.3271 0.1279 39.4167
COLO 680N CTRP2 0.4414 1.7801 0.4413 37.3282
TE-1 CTRP2 0.4609 1.1202 0.4609 37.1978
KYSE-150 CTRP2 1.3862 1.9446 1.3862 31.0332
KYSE-30 CTRP2 1.4006 3.23 1.3943 30.9588
KYSE-140 CTRP2 1.4421 3.4156 1.4314 30.6968
KYSE-510 CTRP2 2.3232 3.1976 2.3231 24.7914
KYSE-410 CTRP2 2.5591 4.0557 2.551 23.2465
TE-6 CTRP2 3.4217 4.9444 3.2998 12.9971
TE-4 CTRP2 3.5841 5.0612 3.5503 16.5049
TE-14 CTRP2 3.8715 4.7276 3.8686 14.486
KYSE-450 CTRP2 7.3491 9.2382 5.359 1.1354
OE19 CTRP2 7.7117 9.5601 5.4052 0.7236
TE-9 CTRP2 8.1749 12.9668 4.1566 4.6369
KYSE-70 CTRP2 8.3829 14.5347 3.5541 6.6828
TE-11 CTRP2 8.5379 10.5803 5.3688 0.4097
KYSE-520 CTRP2 8.748 10.8318 5.36 0.355
KYSE-180 CTRP2 11.5654 21.7835 2.1607 7.8767
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 1.7705 14.7522 -2.2361 39.8214
RPMI-7951 CTRP2 -2.059 -1.1119 -2.059 53.9863
MDA-MB-435S CTRP2 -1.2796 -0.5501 -1.2796 48.7932
LOX-IMVI CTRP2 -1.1031 -0.3736 -1.1031 47.6176
Hs 934.T CTRP2 -0.9232 -0.1781 -0.9232 46.4194
Hs 688(A).T CTRP2 -0.686 -0.014 -0.686 44.8387
COLO 792 CTRP2 -0.6474 0.8987 -0.6475 44.5818
WM88 CTRP2 -0.4654 1.3262 -0.466 43.3712
WM793 CTRP2 -0.3502 1.0274 -0.3502 42.6019
Mel Ho CTRP2 0.0728 1.2059 0.0728 39.7835
COLO 741 CTRP2 0.4028 2.3034 0.4003 37.5933
WM266-4 CTRP2 0.4466 1.3488 0.4466 37.2934
WM1799 CTRP2 0.5647 4.5648 0.3935 37.0257
IPC-298 CTRP2 0.6056 1.0444 0.6056 36.234
WM115 CTRP2 0.6287 2.046 0.6284 36.0809
MeWo CTRP2 0.7049 1.6755 0.7049 35.5723
SK-MEL-30 CTRP2 0.9692 1.9016 0.9692 33.8116
SK-MEL-1 CTRP2 1.0529 2.0413 1.0529 33.254
RVH-421 CTRP2 1.1733 2.3687 1.1732 32.4521
Hs 940.T CTRP2 1.3853 3.0689 1.3818 31.0512
SK-MEL-28 CTRP2 1.3962 2.2171 1.3962 30.9671
HT-144 CTRP2 1.4073 2.1427 1.4073 30.8928
SK-MEL-5 CTRP2 1.4328 2.0619 1.4328 30.7234
Hs 294T CTRP2 1.4488 2.0698 1.4488 30.6166
SK-MEL-3 CTRP2 1.4847 1.9289 1.4847 30.3771
Hs 839.T CTRP2 1.5038 1.8905 1.5038 30.25
WT2-iPS CTRP2 1.5561 2.1247 1.5561 29.9017
Hs 852.T CTRP2 1.7453 6.991 1.0638 30.8949
COLO 829 CTRP2 1.8381 3.2908 1.8358 28.0304
CJM [Human melanoma] CTRP2 2.2142 2.8235 2.2142 25.5173
SK-MEL-31 CTRP2 2.223 3.0245 2.223 25.4587
Hs 895.T CTRP2 2.262 2.9416 2.262 25.1989
IGR-37 CTRP2 2.4306 3.5518 2.4298 24.0783
WM983B CTRP2 2.5887 3.5921 2.5882 23.0242
G-361 CTRP2 3.0973 8.499 1.9371 23.8297
A2058 CTRP2 6.728 9.3349 4.9282 3.5253
A-375 CTRP2 6.7516 12.9024 3.1855 10.6519
Hs 936.T CTRP2 7.2688 9.532 5.1844 1.8248
Mel JuSo CTRP2 7.3504 12.4058 3.8755 6.8708
A101D CTRP2 7.5575 12.3739 4.0346 5.9273
Hs 944.T CTRP2 9.3452 16.9089 3.0547 7.3296
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SiMa CTRP2 -1.4458 -0.3555 -1.4458 49.9007
Kelly CTRP2 -1.3828 -0.1606 -1.3828 49.4809
MHH-NB-11 CTRP2 -0.8912 2.1991 -0.9114 46.2435
SK-N-DZ CTRP2 -0.542 0.297 -0.542 43.8798
SK-N-BE(2) CTRP2 -0.4367 0.7228 -0.4367 43.1777
NB1 CTRP2 -0.2016 0.8887 -0.2016 41.6115
CHP-126 CTRP2 0.0895 1.3547 0.0894 39.6727
SK-N-FI CTRP2 0.2239 2.3218 0.2196 38.7907
SK-N-SH CTRP2 2.3173 8.4076 1.1544 28.7949
KP-N-SI9s CTRP2 5.8334 12.8924 2.443 15.3375
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 CTRP2 -0.6623 0.1884 -0.6623 44.6811
SNU-869 CTRP2 0.0064 1.8171 0.0053 40.2296
HuH-28 CTRP2 0.1792 1.1627 0.1792 39.0749
SNU-1196 CTRP2 0.398 1.2846 0.398 37.6172
SNU-478 CTRP2 0.4402 1.2706 0.4402 37.3359
SNU-1079 CTRP2 8.0023 11.4383 4.7515 2.6196
SNU-308 CTRP2 8.0384 9.2858 5.6425 0.1112
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CADO-ES1 CTRP2 -0.7086 0.365 -0.7086 44.9895
Hs 822.T CTRP2 -0.4565 -0.1184 -0.4565 43.3096
SK-ES-1 CTRP2 -0.3251 0.5296 -0.3251 42.4348
A-673 CTRP2 -0.1911 0.925 -0.1911 41.5416
SJSA-1 CTRP2 0.1806 2.0222 0.1791 39.0704
Hs 888.T CTRP2 0.2368 1.6693 0.2366 38.6915
G-292 clone A141B1 CTRP2 0.4418 1.2209 0.4418 37.3251
SaOS-2 CTRP2 0.6746 2.3108 0.6735 35.7779
MHH-ES-1 CTRP2 0.6927 6.126 0.1814 37.1166
HOS CTRP2 1.2379 3.3901 1.2235 32.0697
CAL-78 CTRP2 1.432 2.7339 1.4315 30.7302
MG-63 CTRP2 2.2035 2.8889 2.2035 25.5886
U2OS CTRP2 7.9558 10.0613 5.3171 0.8145
SW1353 CTRP2 10.0771 21.8642 1.1904 12.7941
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC38 CTRP2 -1.4422 3.1654 -1.557 49.8832
HCC1500 CTRP2 -1.3303 -0.5729 -1.3303 49.1311
HCC1143 CTRP2 -0.9303 0.4509 -0.9303 46.4666
SK-BR-3 CTRP2 -0.896 2.7068 -0.9429 46.3157
ZR-75-1 CTRP2 -0.8385 0.2322 -0.8385 45.8549
CAL-148 CTRP2 -0.7125 0.1702 -0.7125 45.0157
AU565 CTRP2 -0.4919 0.5878 -0.4919 43.5455
MDA-MB-361 CTRP2 -0.4907 0.8415 -0.4907 43.5379
MDA-MB-157 CTRP2 -0.4771 0.7392 -0.4771 43.4471
KPL-1 CTRP2 -0.3669 0.492 -0.3669 42.7132
HCC2218 CTRP2 -0.3454 0.9967 -0.3455 42.5701
Hs 578Bst CTRP2 -0.3261 1.1388 -0.3262 42.4415
HCC1419 CTRP2 -0.2221 1.0075 -0.2221 41.7484
EFM-192A CTRP2 -0.1535 1.4176 -0.1537 41.292
HCC1937 CTRP2 -0.0614 1.4535 -0.0616 40.6784
CAL-51 CTRP2 0.2311 2.7731 0.216 38.7767
BT-474 CTRP2 0.2895 1.1216 0.2895 38.3401
MDA-MB-453 CTRP2 0.3079 1.1521 0.3079 38.2176
ZR-75-30 CTRP2 0.346 2.4358 0.3412 37.9793
T-47D CTRP2 0.6432 2.4373 0.6411 35.9905
BT-20 CTRP2 0.8663 1.7894 0.8663 34.4972
CAL-85-1 CTRP2 1.3338 4.1152 1.274 31.5815
MDA-MB-468 CTRP2 1.6834 3.0049 1.6825 29.0565
HDQ-P1 CTRP2 2.6182 4.8451 2.5515 23.0515
CAL-120 CTRP2 3.0601 3.9499 3.0596 19.8836
HCC1954 CTRP2 7.4189 13.0112 3.6294 7.7584
MDA-MB-231 CTRP2 7.6406 12.0829 4.2293 5.039
JIMT-1 CTRP2 7.6572 12.7305 3.9312 6.1984
HCC1806 CTRP2 8.0889 9.9866 5.4062 0.5155
MCF-7 CTRP2 8.2091 14.7926 3.3163 7.8362
CAMA-1 CTRP2 8.438 26.1013 -2.0658 23.9223
HMC-1-8 CTRP2 8.5483 15.6221 3.1471 8.0156
HCC1395 CTRP2 8.8459 16.9976 2.6898 9.3194
BT 504 CTRP2 -1.2394 0.1798 -1.2395 48.526
BT 172 CTRP2 -0.5559 0.2864 -0.5559 43.9724
BT147 CTRP2 -0.3296 0.6821 -0.3296 42.4647
BT 271 CTRP2 -0.3083 0.8901 -0.3083 42.3224
BT 187 CTRP2 -0.2098 0.7498 -0.2098 41.6662
BT 286 CTRP2 -0.1244 2.2687 -0.1319 41.1203
BT 139 CTRP2 -0.0027 1.048 -0.0027 40.2866
BT 330 CTRP2 0.0152 2.5437 0.003 40.205
BT 232 CTRP2 0.2033 1.9174 0.2024 38.9174
BT 416 CTRP2 0.2892 3.1992 0.2553 38.4476
BT 239 CTRP2 0.3261 1.2564 0.3261 38.0963
BT 440 CTRP2 0.3644 1.7667 0.3643 37.8412
BT 422 CTRP2 0.4109 0.9046 0.4109 37.5312
BT 248 CTRP2 0.4414 2.0033 0.4408 37.33
BT 216 CTRP2 0.6665 1.8387 0.6665 35.8285
BT 131 CTRP2 0.6788 2.1231 0.6785 35.7473
BT 482 CTRP2 1.2862 3.2818 1.2767 31.7314
BT 428 CTRP2 1.3429 3.0721 1.3389 31.3352
BT 231 CTRP2 1.3915 3.9066 1.3528 31.1275
BT 159 CTRP2 1.408 2.7209 1.4075 30.8901
BT 340 CTRP2 1.421 3.1964 1.4157 30.8192
BT 333 CTRP2 1.4703 2.3607 1.4703 30.4735
BT 228 CTRP2 1.6786 6.5253 1.1403 30.8705
BT 245 CTRP2 1.7072 3.8043 1.6871 28.9623
BT 498 CTRP2 1.7795 2.9658 1.7791 28.4144
BT 444 CTRP2 1.8323 2.8174 1.8322 28.0618
BT 328 CTRP2 2.6221 3.9032 2.6188 22.8107
BT 359 CTRP2 3.4122 4.2991 3.411 17.5399
BT 224 CTRP2 7.6971 10.5076 4.9932 2.0682
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 0.1933 0.882 0.1933 38.9809
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LN-229 CTRP2 -0.4181 0.7596 -0.4181 43.054
SF539 CTRP2 -0.2349 0.9216 -0.2349 41.8337
KALS-1 CTRP2 -0.1846 1.167 -0.1846 41.4985
U-118MG CTRP2 -0.0526 1.9041 -0.0545 40.6253
SNU-466 CTRP2 0.2231 0.9393 0.2231 38.7821
Daoy CTRP2 0.2302 1.4693 0.2302 38.7352
CAS-1 CTRP2 0.2527 1.8222 0.2523 38.5866
KNS-60 CTRP2 0.3986 1.1332 0.3986 37.6128
YH-13 CTRP2 0.4765 1.5159 0.4765 37.0938
SNU-626 CTRP2 0.6337 1.2651 0.6337 36.0467
SNU-738 CTRP2 0.6934 1.3303 0.6934 35.6494
SF295 CTRP2 0.8912 2.0683 0.8911 34.3315
SW1088 CTRP2 1.1142 2.3892 1.114 32.8464
GB-1 CTRP2 1.2661 2.8086 1.2646 31.8388
U-251MG CTRP2 1.8356 3.4328 1.8312 28.0544
Hs 683 CTRP2 1.9906 3.2187 1.9898 27.0096
SF126 CTRP2 2.0195 3.704 2.0115 26.8413
KG-1-C CTRP2 2.25 3.1031 2.25 25.2786
SNB-75 CTRP2 2.2635 4.4235 2.2224 25.327
T98G CTRP2 2.2805 8.6625 1.0125 29.3581
KNS-81 CTRP2 2.5522 3.1061 2.5522 23.2654
42-MG-BA CTRP2 2.5669 3.567 2.5664 23.1692
SF268 CTRP2 2.6958 4.3818 2.6765 22.3737
Becker CTRP2 2.9802 4.0955 2.9777 20.4225
GaMG CTRP2 3.5274 4.5145 3.5241 16.7798
NMC-G1 CTRP2 4.295 5.3699 4.2683 11.7448
GOS-3 CTRP2 5.3978 12.0614 2.4814 16.0966
M059K CTRP2 6.5885 11.2244 3.8927 8.0383
TM-31 CTRP2 6.8973 11.0499 4.212 6.2015
LN-18 CTRP2 7.1069 9.3797 5.1571 2.1087
8-MG-BA CTRP2 7.4341 9.9985 5.0703 2.0639
ONS-76 CTRP2 7.6384 9.534 5.381 0.8412
U-87MG ATCC CTRP2 7.9105 9.2687 5.601 0.1965
CCF-STTG1 CTRP2 8.1869 13.1358 4.0855 4.8936
DBTRG-05MG CTRP2 8.4589 13.2646 4.1929 4.1675
SNU-201 CTRP2 9.3341 17.1863 2.9183 7.8403
SNU-1105 CTRP2 9.9283 17.506 3.1357 6.3575
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 -1.6808 -0.2258 -1.6808 51.466
ESS-1 CTRP2 -1.441 -0.9973 -1.441 49.8686
JHUEM-1 CTRP2 -0.7078 -0.0746 -0.7078 44.9838
RL95-2 CTRP2 -0.494 2.6842 -0.5252 43.6367
HEC-1-A CTRP2 -0.3209 0.7282 -0.3209 42.4062
KLE CTRP2 0.465 1.7368 0.4649 37.1712
EFE-184 CTRP2 0.5654 1.5639 0.5654 36.5019
AN3-CA CTRP2 0.7832 3.0043 0.7721 35.0874
MFE-296 CTRP2 1.0409 2.7034 1.0388 33.341
HEC-151 CTRP2 1.6981 2.3959 1.6981 28.9556
EN CTRP2 1.8711 3.1158 1.8704 27.8054
MFE-319 CTRP2 2.5181 3.7867 2.5155 23.5012
HEC-6 CTRP2 7.5753 13.8032 3.355 8.6148
HEC-50B CTRP2 7.8314 14.5963 2.3432 7.3704
HEC-251 CTRP2 8.3064 15.5321 3.0276 8.8078
HEC-59 CTRP2 8.5702 14.4761 3.7016 5.8801
HEC-1-B CTRP2 8.9773 20.6779 1.0045 14.9494
HEC-108 CTRP2 11.4989 20.7653 2.5791 6.593
Ishikawa (Heraklio) 02 ER- CTRP2 7.0208 9.1003 5.2332 1.922
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 -0.6928 0.4368 -0.6928 44.8839
VMRC-RCW CTRP2 0.4652 2.1876 0.464 37.1734
RCC10RGB CTRP2 0.5791 1.3305 0.5791 36.4105
TUHR14TKB CTRP2 0.6054 2.5603 0.6015 36.2484
786-O CTRP2 1.0587 1.8053 1.0587 33.2152
BFTC-909 CTRP2 1.0983 1.9956 1.0983 32.9518
KMRC-3 CTRP2 1.8404 2.8963 1.8403 28.0078
Caki-1 CTRP2 1.8575 2.7093 1.8574 27.894
ACHN CTRP2 1.8754 3.4427 1.8712 27.7885
VMRC-RCZ CTRP2 1.914 2.8618 1.914 27.5173
TUHR4TKB CTRP2 2.1092 3.439 2.1074 26.223
KMRC-2 CTRP2 2.3462 2.8818 2.3462 24.6377
KMRC-1 CTRP2 2.9383 4.2811 2.9308 20.7181
TUHR10TKB CTRP2 7.5221 8.7606 5.6336 0.2635
769-P CTRP2 7.6173 9.2948 5.4681 0.6099
Caki-2 CTRP2 7.9656 9.7213 5.4552 0.4603
SNU-1272 CTRP2 8.0568 13.9075 3.637 6.8007
OS-RC-2 CTRP2 9.2752 18.1314 2.4349 9.6626
KMRC-20 CTRP2 10.424 23.6989 0.5464 14.305
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
T84 CTRP2 -0.8119 1.2664 -0.8133 45.6811
NCI-H747 CTRP2 -0.7949 0.5728 -0.7949 45.5643
SNU-1033 CTRP2 -0.5865 1.293 -0.5873 44.1784
HCT 15 CTRP2 -0.5257 1.3586 -0.5265 43.773
SNU-C5 CTRP2 -0.5211 0.7773 -0.5211 43.7401
SNU-61 CTRP2 -0.3202 0.7511 -0.3202 42.4021
LS1034 CTRP2 -0.2799 1.7882 -0.2821 42.1401
LS513 CTRP2 -0.2067 0.6333 -0.2067 41.6458
DLD-1 CTRP2 -0.1739 0.4353 -0.1739 41.427
SW1417 CTRP2 -0.1554 1.2791 -0.1555 41.3044
SW48 CTRP2 -0.0234 0.8928 -0.0234 40.4244
SK-CO-1 CTRP2 0.1388 1.3266 0.1388 39.3438
LS123 CTRP2 0.3145 1.1039 0.3145 38.1731
HT-55 CTRP2 0.5467 1.3694 0.5467 36.6262
LS180 CTRP2 0.5736 1.3214 0.5736 36.4474
HCT 116 CTRP2 0.6345 8.759 -0.7726 39.4007
OUMS-23 CTRP2 0.7568 1.5156 0.7568 35.2268
COLO 320 CTRP2 0.7696 2.2851 0.769 35.1435
CL-11 CTRP2 0.784 2.4648 0.7824 35.0507
SNU-175 CTRP2 0.8021 6.2921 0.2538 36.5211
SW1116 CTRP2 0.8845 1.8824 0.8845 39.7149
SNU-81 CTRP2 0.9458 2.5523 0.9444 33.9721
RKO CTRP2 1.0076 2.4437 1.007 33.5577
SW620 CTRP2 1.1235 2.8386 1.1207 32.7931
COLO 678 CTRP2 1.2524 2.3209 1.2523 31.9254
SW1463 CTRP2 1.2707 2.432 1.2706 31.8034
HCC-56 CTRP2 1.2999 1.9523 1.2999 31.6083
HCT 8 CTRP2 1.3965 2.0937 1.3965 30.965
KM12 CTRP2 1.5561 2.5535 1.5561 29.9017
SNU-C1 CTRP2 1.7137 2.3833 1.7137 28.8519
SNU-407 CTRP2 1.779 2.8602 1.7789 28.4169
SNU-C4 CTRP2 1.7957 2.3407 1.7957 28.3057
MDST8 CTRP2 4.1158 9.0417 2.7414 18.0743
HT115 CTRP2 4.9462 10.2724 2.9576 15.2107
SNU-C2A CTRP2 6.2021 15.2253 1.5847 17.7709
COLO205 CTRP2 7.15 9.2586 5.2384 1.7556
COLO201 CTRP2 7.2429 8.8145 5.4846 0.8177
HT-29 CTRP2 7.6334 9.1679 5.5253 0.4552
LS411N CTRP2 7.6355 9.2044 5.512 0.4866
LoVo CTRP2 7.7261 11.3046 4.6486 3.3046
NCI-H716 CTRP2 8.4938 10.1828 5.4959 0.2073
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 -0.0416 1.9313 -0.0437 40.5526
JHH-2 CTRP2 0.097 2.7712 0.0788 39.6783
HuH-6 CTRP2 0.1183 2.0812 0.1159 39.4883
PLC/PRF/5 CTRP2 0.1527 1.9798 0.1513 39.2558
Li-7 CTRP2 0.453 1.3284 0.453 37.2505
SNU-761 CTRP2 0.9726 1.9497 0.9725 31.3835
SNU-423 CTRP2 1.5032 2.5398 1.5031 30.2544
JHH-5 CTRP2 1.5265 2.5269 1.5264 30.0992
SK-HEP-1 CTRP2 1.5342 1.9507 1.5342 30.0473
JHH-6 CTRP2 2.4184 13.8615 -1.1835 34.4942
SNU-878 CTRP2 6.7223 9.1694 5.0045 3.223
Hep-G2 CTRP2 6.8129 9.6418 4.839 3.7617
JHH-1 CTRP2 6.982 9.3944 5.0715 2.5943
HLF CTRP2 7.2496 13.26 3.3851 9.0073
Hep 3B2.1-7 CTRP2 7.3331 11.6637 4.2227 5.495
SNU-475 CTRP2 7.4805 10.1432 5.032 2.1537
SNU-398 CTRP2 7.5466 11.4759 4.4553 4.2744
HuH-1 CTRP2 7.7414 16.6473 2.0822 13.2175
JHH-4 CTRP2 9.0104 16.5358 3.0166 7.8917
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 121 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H209 CTRP2 -3.5359 1.664 -3.6171 62.5834
NCI-H1581 CTRP2 -2.3285 -1.3626 -2.3285 55.7812
NCI-H1155 CTRP2 -2.2271 -0.9628 -2.2271 55.1061
NCI-H1184 CTRP2 -2.1165 -0.2952 -2.1166 54.3681
NCI-H1734 CTRP2 -1.864 -0.4637 -1.864 52.6871
NCI-H2106 CTRP2 -1.7252 -0.399 -1.7252 51.7624
DMS 79 CTRP2 -1.5982 0.1069 -1.5983 50.9158
NCI-H2087 CTRP2 -1.4202 0.2801 -1.4203 49.7299
NCI-H211 CTRP2 -1.3251 0.9153 -1.3266 49.0978
DMS 53 CTRP2 -1.1815 0.1033 -1.1816 48.1403
NCI-H1694 CTRP2 -1.1655 0.0692 -1.1655 48.0333
Calu-6 CTRP2 -1.1585 -0.2157 -1.1585 47.9865
NCI-H522 CTRP2 -0.9709 0.4062 -0.9709 46.7369
Calu-1 CTRP2 -0.9095 0.0247 -0.9095 46.328
NCI-H1975 CTRP2 -0.9018 0.0724 -0.9018 46.2768
Sq-1 CTRP2 -0.8441 0.9437 -0.8444 45.893
NCI-H1650 CTRP2 -0.7875 0.4663 -0.7875 45.5148
NCI-H1703 CTRP2 -0.7853 -0.0904 -0.7853 45.5007
COR-L95 CTRP2 -0.7487 0.4523 -0.7487 45.2566
NCI-H1385 CTRP2 -0.747 1.4672 -0.7494 45.2513
NCI-H1666 CTRP2 -0.7394 0.909 -0.7396 45.1952
SW1271 CTRP2 -0.5937 0.9994 -0.5938 44.2243
NCI-H1092 CTRP2 -0.5932 0.4812 -0.5932 44.2208
HCC1588 CTRP2 -0.4862 0.5467 -0.4862 43.508
Lu-99 CTRP2 -0.4147 0.1974 -0.4147 43.0316
HCC1171 CTRP2 -0.3598 0.9564 -0.3598 42.6655
HCC78 CTRP2 -0.2313 0.7893 -0.2313 41.8094
LCLC-97TM1 CTRP2 -0.0713 2.7363 -0.0924 40.8062
RERF-LC-Ad1 CTRP2 -0.0227 0.6535 -0.0227 40.4199
NCI-H69 CTRP2 0.0095 1.3281 0.0095 40.2053
RERF-LC-A1 CTRP2 0.049 2.3007 0.0431 39.961
NCI-H2196 CTRP2 0.0573 1.4382 0.0572 39.8875
HCC2108 CTRP2 0.0629 5.6772 -0.3869 40.924
NCI-H889 CTRP2 0.1296 1.534 0.1295 39.4055
HCC2935 CTRP2 0.2109 1.5979 0.2108 38.8639
NCI-H2444 CTRP2 0.2745 1.1473 0.2745 36.7638
NCI-H1563 CTRP2 0.2895 2.6656 0.2789 38.374
HCC1833 CTRP2 0.2949 1.4035 0.2949 38.3037
HCC44 CTRP2 0.2957 1.8823 0.2952 38.3005
SHP-77 CTRP2 0.3135 0.9075 0.3135 38.1799
HCC1195 CTRP2 0.3161 1.2744 0.3161 38.1626
NCI-H838 CTRP2 0.3769 1.4768 0.3769 37.7575
NCI-H1299 CTRP2 0.3773 1.8746 0.377 37.756
EBC-1 CTRP2 0.4059 2.6147 0.3986 37.5881
NCI-H727 CTRP2 0.4135 1.1655 0.4135 37.514
DMS 454 CTRP2 0.4398 2.4351 0.436 37.3511
SBC-5 CTRP2 0.4412 1.1843 0.4412 37.3295
NCI-H196 CTRP2 0.4675 1.6063 0.4674 37.1544
EPLC-272H CTRP2 0.4689 3.6216 0.4111 37.326
NCI-H358 CTRP2 0.5097 1.93 0.5094 36.874
NCI-H1105 CTRP2 0.5107 2.1803 0.5096 36.87
SK-LU-1 CTRP2 0.5168 1.2846 0.5168 36.8259
NCI-H2228 CTRP2 0.5183 2.1342 0.5175 36.8186
Calu-3 CTRP2 0.5771 2.8257 0.5674 36.4556
HCC4006 CTRP2 0.5932 2.4088 0.5909 36.3242
NCI-H226 CTRP2 0.6728 1.2321 0.6728 35.7861
NCI-H1568 CTRP2 0.722 1.766 0.722 35.4588
NCI-H1339 CTRP2 0.7353 1.6424 0.7353 35.3701
NCI-H1869 CTRP2 0.7399 3.2315 0.719 35.4079
NCI-H841 CTRP2 0.7439 3.3243 0.7184 35.3961
HCC366 CTRP2 0.7962 1.6544 0.7962 34.9643
NCI-H526 CTRP2 0.8218 1.5894 0.8218 34.7934
NCI-H446 CTRP2 1.0279 2.5823 1.0267 33.4245
NCI-H2342 CTRP2 1.035 3.3558 1.0168 33.4336
HCC15 CTRP2 1.1008 2.7811 1.0984 32.9429
NCI-H1755 CTRP2 1.2299 2.224 1.2299 32.0746
HCC2279 CTRP2 1.2511 2.6799 1.2503 31.9361
HOP-92 CTRP2 1.3034 2.5218 1.3032 31.5856
DMS 273 CTRP2 1.3322 2.7498 1.3314 31.3959
NCI-H1395 CTRP2 1.4068 2.4357 1.4067 30.8966
NCI-H292 CTRP2 1.5486 2.5079 1.5486 29.9518
NCI-H2291 CTRP2 1.5653 9.1549 0.0585 34.3366
COR-L105 CTRP2 1.5828 2.4447 1.5828 29.7238
CAL-12T CTRP2 1.6 2.8923 1.5993 29.6115
NCI-H322 CTRP2 1.8781 3.1353 1.8773 27.7591
HOP-62 CTRP2 1.8829 4.654 1.7931 28.0271
HCC1438 CTRP2 1.922 2.8975 1.9219 27.4645
HARA [Human squamous cell lung carcinoma] CTRP2 1.9227 2.8155 1.9226 27.4598
PC-14 CTRP2 1.9312 3.0295 1.931 27.4033
DMS 114 CTRP2 2.1139 3.5398 2.1109 26.1956
NCI-H1915 CTRP2 2.2335 4.0448 2.2175 25.4423
SK-MES-1 CTRP2 2.3656 3.4403 2.3651 24.5101
KNS-62 CTRP2 2.5056 3.6582 2.5044 23.5799
NCI-H1651 CTRP2 2.5786 9.521 0.9624 28.6163
EKVX CTRP2 2.5801 3.8026 2.5779 23.087
NCI-H1355 CTRP2 2.608 4.3086 2.5899 22.9545
NCI-H1573 CTRP2 2.6345 3.302 2.6345 22.7174
NCI-H2286 CTRP2 2.6353 3.9022 2.2446 5.3717
NCI-H2110 CTRP2 2.6653 4.019 2.6603 22.5287
NCI-H1838 CTRP2 2.6681 4.8094 2.6089 22.6935
LUDLU-1 CTRP2 2.7843 4.0369 2.7806 21.7314
NCI-H520 CTRP2 3.0409 7.1857 2.3968 22.3159
NCI-H1793 CTRP2 3.4175 4.2301 3.4169 17.503
NCI-H1944 CTRP2 4.0485 5.723 3.9448 13.6539
NCI-H2085 CTRP2 5.0044 12.6575 1.2044 16.9293
A-549 CTRP2 5.9875 10.5242 3.7569 9.716
MOR/CPR CTRP2 6.1136 14.6845 1.7819 17.2448
NCI-H1373 CTRP2 6.4721 11.5008 3.6639 9.1925
NCI-H1435 CTRP2 6.4942 11.3001 3.7813 8.6668
NCI-H2009 CTRP2 6.69 13.3983 2.8907 11.9411
BEN CTRP2 7.3357 9.2581 5.3433 1.1999
NCI-H2126 CTRP2 7.4444 12.7729 3.7634 7.1808
HCC827 CTRP2 7.4458 14.3304 3.0033 10.2083
NCI-H441 CTRP2 7.4792 11.7293 4.2905 5.0169
LXF 289 CTRP2 7.5402 14.6092 2.9356 10.3217
NCI-H460 CTRP2 7.6202 10.6737 4.8738 2.5829
NCI-H2030 CTRP2 7.6495 12.2857 4.1388 5.3848
NCI-H2172 CTRP2 7.711 9.287 5.5129 0.4464
NCI-H2023 CTRP2 7.9288 11.422 4.7163 2.8245
LCLC-103H CTRP2 7.942 9.1089 5.6689 0.0979
LC-1/sq-SF CTRP2 7.9538 9.2815 5.6129 0.1673
NCI-H1792 CTRP2 7.9567 12.5683 4.2051 4.7211
LOU-NH91 CTRP2 7.9878 12.6195 4.2009 4.6981
NCI-H2122 CTRP2 8.0083 9.7707 5.4545 0.443
COLO 699 CTRP2 8.0103 18.1538 1.5397 14.6937
HCC95 CTRP2 8.0796 9.585 5.5522 0.2283
NCI-H1623 CTRP2 8.6587 10.5028 5.4442 0.2428
NCI-H661 CTRP2 8.6882 17.2919 1.6256 8.9846
NCI-H2405 CTRP2 8.9168 10.5804 5.5111 0.1123
NCI-H650 CTRP2 9.2467 17.2399 2.8374 8.2456
Hs 888.Lu CTRP2 1.6656 2.587 1.6656 29.1721
⏷ Show the Full List of 121 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -0.305 3.7761 -0.4229 42.5836
A2780 CTRP2 -2.0114 -0.5207 -2.0114 53.6688
OC 314 CTRP2 -0.6415 -0.0816 -0.6415 44.5425
OV7 CTRP2 -0.2485 1.3936 -0.2488 41.9253
OVCAR-5 CTRP2 -0.1804 0.7308 -0.1804 41.4703
JHOS-2 CTRP2 0.0094 1.2459 0.0094 40.2058
SNU-119 CTRP2 0.0836 1.3624 0.0836 39.7116
TYK-nu CTRP2 0.0848 1.8334 0.0839 39.7069
OVK18 CTRP2 0.0936 2.5382 0.083 39.6782
SNU-840 CTRP2 0.306 1.1632 0.306 38.2297
OVCAR-4 CTRP2 0.3273 1.4306 0.3273 38.0884
ONCO-DG-1 CTRP2 0.33 1.1409 0.33 38.0704
SNU-8 CTRP2 0.3666 0.8628 0.3666 37.8261
TOV-112D CTRP2 0.7465 2.3002 0.7457 35.298
COV434 CTRP2 0.8147 2.8939 0.8072 34.8659
HEY A8 CTRP2 1.2456 2.3134 1.2455 31.9705
COV362 CTRP2 1.2955 2.981 1.2924 31.6482
MCAS CTRP2 1.3144 3.0313 1.3108 31.5239
Caov-3 CTRP2 1.3444 5.7295 0.9976 32.4417
Kuramochi CTRP2 1.3545 7.7885 0.3627 34.2603
IGROV-1 CTRP2 1.4118 4.2607 1.341 31.099
EFO-21 CTRP2 1.4159 1.951 1.4159 30.8359
OV-90 CTRP2 1.5718 2.0587 1.5718 29.7973
OAW42 CTRP2 3.2504 4.7647 3.2269 18.6927
OV56 CTRP2 5.6512 10.2898 3.5858 11.1055
OVISE CTRP2 7.6077 8.9321 5.6044 0.2896
ES2 CTRP2 7.7925 9.0323 5.6407 0.1659
DOV13 CTRP2 7.8802 9.2901 5.5815 0.2379
FU-OV-1 CTRP2 8.0579 12.4144 4.3401 4.0805
JHOM-1 CTRP2 8.1826 12.8083 4.2348 4.3308
RMG-I CTRP2 8.389 14.3476 3.6463 6.3212
OAW28 CTRP2 8.5935 14.2655 3.8142 5.4264
OVCAR-8 CTRP2 8.8233 15.7577 3.2623 7.2174
JHOC-5 CTRP2 9.0721 16.0982 3.2609 6.9088
SK-OV-3 CTRP2 9.1552 14.8291 3.8938 4.4955
OVTOKO CTRP2 9.3758 16.9978 3.0324 7.3733
OVSAHO CTRP2 11.8478 26.609 0.1029 13.7669
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 2.847 10.455 0.8227 28.2677
Yamato-SS CTRP2 3.432 9.0696 2.0367 22.5406
A-204 CTRP2 -2.389 -0.799 -2.389 56.1841
G-401 CTRP2 -1.3338 -0.2494 -1.3338 49.1546
Rh41 CTRP2 -1.1685 0.2004 -1.1685 48.0534
Rh18 CTRP2 -1.0992 0.9054 -1.0999 47.5928
KYM-1 CTRP2 -0.7343 0.3392 -0.7343 45.1605
TTC-709 CTRP2 -0.6938 1.1024 -0.6943 44.8923
GCT CTRP2 -0.3113 1.2528 -0.3115 42.343
G-402 CTRP2 -0.2186 1.4195 -0.219 41.7262
TE 617.T CTRP2 -0.2107 1.6215 -0.2116 41.6753
SW982 CTRP2 0.6077 3.6122 0.5574 36.3808
Hs 729.T CTRP2 0.6268 1.822 0.6267 36.093
MES-SA CTRP2 0.6729 1.9808 0.6727 35.7864
Tm87-16 CTRP2 0.8957 4.8332 0.7038 34.9092
SK-UT-1 CTRP2 0.9695 3.1489 0.9576 33.8492
HT-1080 CTRP2 1.203 1.9405 1.203 32.2542
SK-LMS-1 CTRP2 1.4907 2.0885 1.4907 30.3377
BT-12 CTRP2 6.967 11.404 4.0892 6.5948
BT-16 CTRP2 7.877 9.0229 5.6752 0.1019
RKN CTRP2 7.9743 9.0867 5.6879 0.0737
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 6.3371 17.1396 0.7388 20.3173
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Capan-2 CTRP2 -0.8723 0.7908 -0.8725 46.0807
KP-4 CTRP2 -0.4808 0.8521 -0.4808 43.4716
Panc 08.13 CTRP2 -0.4063 1.0774 -0.4064 42.9759
SW1990 CTRP2 -0.2787 1.5834 -0.2797 42.1285
KP-3 CTRP2 -0.1225 1.3547 -0.1226 41.0851
Panc 10.05 CTRP2 0.0861 2.2384 0.0816 39.7093
PK-59 CTRP2 0.1351 5.4786 -0.2593 40.356
BxPC-3 CTRP2 0.3228 1.1654 0.3228 38.118
HuP-T4 CTRP2 0.567 1.3171 0.567 36.4913
L3.3 CTRP2 0.6027 1.3221 0.6027 36.2532
HuP-T3 CTRP2 0.6799 1.8962 0.6798 35.7394
Panc 03.27 CTRP2 0.6803 2.6751 0.6754 35.7524
SU.86.86 CTRP2 0.9303 2.4178 0.9296 34.0732
Panc 04.03 CTRP2 1.0483 1.9037 1.0483 33.285
Panc 02.03 CTRP2 1.1152 1.9656 1.1152 32.8391
SNU-410 CTRP2 1.1623 6.0486 0.7153 33.9341
PSN1 CTRP2 1.5779 2.1733 1.5779 29.7562
KP-2 CTRP2 1.8599 2.5171 1.8599 27.878
DAN-G CTRP2 2.2348 4.1424 2.2135 25.4511
PaTu 8902 CTRP2 2.5899 3.1085 2.5899 23.0143
AsPC-1 CTRP2 4.4627 9.6383 2.8043 16.9622
YAPC CTRP2 5.8942 8.9892 4.445 7.0183
Hs 766T CTRP2 7.2535 10.325 4.8083 3.2728
SNU-213 CTRP2 7.3631 9.1351 5.4104 0.9569
HPAC CTRP2 7.6774 9.8537 5.2669 1.1605
PaTu 8988t CTRP2 7.7247 9.0476 5.6089 0.2389
SUIT-2 CTRP2 8.0191 9.4434 5.5798 0.2006
HPAF-II CTRP2 8.1534 10.0442 5.4116 0.4741
CFPAC-1 CTRP2 8.183 10.1432 5.3864 0.5174
Panc 05.04 CTRP2 8.2293 16.0328 2.7331 10.0382
QGP-1 CTRP2 8.3866 9.6867 5.6286 0.0746
TCC-Pan2 CTRP2 8.9573 17.2335 2.6516 9.3073
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 CTRP2 -1.6911 -0.1998 -1.6911 51.5347
NCI-H2452 CTRP2 0.352 1.59 0.352 37.9236
NCI-H2052 CTRP2 7.6797 10.2124 5.1137 1.6645
JL-1 CTRP2 8.018 11.9754 4.5176 3.4597
ACC-MESO-1 CTRP2 8.2947 15.0017 3.2738 7.8803
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 CTRP2 0.7733 2.2012 0.7729 35.1181
PaCa-3 CTRP2 2.1747 3.2268 2.1744 25.7812
22Rv1 CTRP2 8.8685 15.6642 3.335 6.8875
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 2.229 4.3375 2.1937 25.5374
YD-15 CTRP2 5.2518 10.2237 3.2623 13.2915
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-N87 CTRP2 -1.2895 0.8918 -1.2907 48.8604
GSS CTRP2 -0.6965 0.3252 -0.6965 44.9088
HGC-27 CTRP2 -0.6531 0.4027 -0.6531 44.6196
SNU-216 CTRP2 -0.2803 1.0784 -0.2804 42.1364
NCC-StC-K140 CTRP2 0.0129 1.7727 0.012 40.1858
SNU-601 CTRP2 0.3981 1.5028 0.3981 37.6164
23132/87 CTRP2 0.5185 1.1225 0.5185 36.8141
MKN1 CTRP2 0.6226 1.3037 0.6226 36.1207
MKN74 CTRP2 0.785 2.9628 0.7752 35.0712
SNU-16 CTRP2 0.7997 1.4353 0.7997 34.9412
ECC10 CTRP2 0.8991 2.453 0.8981 34.282
SNU-1 CTRP2 1.1757 2.5124 1.1753 32.4372
HuG1-N CTRP2 1.5872 2.1759 1.5872 29.6943
LMSU CTRP2 1.8123 2.4122 1.8123 28.195
Hs 746.T CTRP2 3.9666 5.239 3.9354 13.948
KE-39 CTRP2 4.5835 10.2167 2.6435 17.3031
NUGC-4 CTRP2 5.9397 10.6469 3.6553 10.2325
Fu97 CTRP2 6.701 10.4626 3.5599 3.9343
NUGC-3 CTRP2 6.7649 12.6988 3.2969 10.1777
ECC12 CTRP2 6.8281 11.046 4.1628 6.5155
MKN45 CTRP2 7.0632 8.5136 5.5199 0.8515
IM95 CTRP2 7.897 14.7576 3.1185 9.056
SNU-668 CTRP2 8.6311 15.997 3.0236 8.3697
SNU-719 CTRP2 9.0093 16.1726 3.1865 7.2631
AGS CTRP2 10.5161 21.7978 1.5097 11.1994
SNG-M CTRP2 1.8177 3.45 1.8127 28.1755
SNU-1077 CTRP2 7.0334 12.5302 3.5843 8.5539
SNU-685 CTRP2 8.1168 12.3892 4.3876 3.8322
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ML-1 [Human leukemia] CTRP2 0.472 2.0507 0.4714 37.1262
8305C CTRP2 0.5345 1.5834 0.5345 36.7077
CAL-62 CTRP2 0.6823 1.9252 0.6822 35.7232
8505C CTRP2 0.7223 1.893 0.7222 35.4569
B-CPAP CTRP2 0.901 1.7389 0.901 34.2661
SW579 CTRP2 1.4234 2.5155 1.4233 30.7861
TT2609-C02 CTRP2 1.5446 2.204 1.5446 29.978
CGTH-W-1 CTRP2 5.6508 14.0669 1.7006 18.477
FTC-238 CTRP2 6.8901 12.9369 3.275 10.0495
TT CTRP2 8.26 17.3703 2.1049 12.3107
BHT-101 CTRP2 10.3478 18.4464 2.9566 6.5221
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-4 CTRP2 -0.2319 1.699 -0.2333 41.818
SNU-46 CTRP2 -0.2264 4.6865 -0.4819 42.3565
SCC-25 CTRP2 0.5652 1.9635 0.565 36.5038
FaDu CTRP2 0.8136 1.7017 0.8136 34.8486
YD-8 CTRP2 0.8277 2.6527 0.8246 34.7644
HSC-2 CTRP2 1.3048 1.8649 1.3048 31.5757
PE/CA-PJ49 CTRP2 1.327 2.0678 1.327 31.4277
PE/CA-PJ34 (clone C12) CTRP2 1.3613 2.6371 1.3609 31.201
SCC-9 CTRP2 1.4165 2.1876 1.4165 30.8316
YD-10B CTRP2 1.5051 3.7314 1.4824 30.317
PE/CA-PJ41 (clone D2) CTRP2 1.5294 2.0655 1.5294 30.0798
PE/CA-PJ15 CTRP2 1.5527 3.9104 1.5205 30.032
BICR 22 CTRP2 1.7839 2.5116 1.7838 28.3844
HSC-4 CTRP2 1.9284 3.3245 1.9264 27.428
BICR 16 CTRP2 2.6241 4.2664 2.6088 22.8377
BICR 56 CTRP2 3.1442 4.5607 3.13 19.3689
CAL-33 CTRP2 3.8264 4.9554 3.8129 14.8219
Detroit 562 CTRP2 6.8638 10.7432 4.338 5.7361
SNU-1214 CTRP2 7.0676 12.2165 3.764 7.7656
HSC-3 CTRP2 8.2706 16.0936 2.7324 9.9798
SNU-899 CTRP2 8.4772 14.877 3.4537 6.943
SNU-1041 CTRP2 8.4935 12.1177 4.7241 2.2438
BHY CTRP2 10.07 23.5917 0.3568 15.3451
SNU-1076 CTRP2 11.0409 24.851 0.4082 13.9037
SNU-1066 CTRP2 13.091 25.6851 1.2891 8.9916
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 CTRP2 -1.3656 -0.9016 -1.3656 49.3664
JMSU-1 CTRP2 -0.7903 0.8727 -0.7905 45.5342
CAL-29 CTRP2 -0.094 0.8998 -0.094 40.8948
TCCSUP CTRP2 0.1685 1.741 0.1681 39.1472
BFTC-905 CTRP2 0.5316 1.1683 0.5316 36.7268
VM-CUB-1 CTRP2 0.533 2.1467 0.5322 36.7202
5637 CTRP2 0.619 2.3283 0.6176 36.1493
U-BLC1 CTRP2 0.9187 2.0364 0.9187 34.1482
T24 CTRP2 1.1971 2.4832 1.1968 32.2942
253J-BV CTRP2 1.2093 2.6982 1.2082 32.2159
UM-UC-1 CTRP2 1.7335 2.4474 1.7335 28.7199
UM-UC-3 CTRP2 1.9466 3.8661 1.9307 27.353
KMBC-2 CTRP2 2.2741 3.1092 2.274 25.1186
SW1710 CTRP2 2.5418 3.5867 2.5412 23.3368
BC-3C CTRP2 3.8344 5.7312 3.7103 15.1518
253J CTRP2 4.3599 6.7433 3.977 12.6098
HT-1376 CTRP2 6.4975 13.3774 2.7483 12.8555
SCaBER CTRP2 6.9325 12.976 3.2881 9.9243
639V CTRP2 7.033 13.2231 3.242 9.9397
KU-19-19 CTRP2 7.422 8.7235 5.6056 0.3679
RT-4 CTRP2 7.5426 10.7887 4.7741 3.0462
RT-112 CTRP2 7.7095 13.8126 3.4453 8.0534
647V CTRP2 8.9565 16.9558 2.783 8.8257
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.1861 8.2975 5.668 0.3354

References

1 Emerging therapies targeting the ubiquitin proteasome system in cancer. J Clin Invest. 2014 Jan;124(1):6-12.