Details of the Drug

General Information of Drug (ID: DMKGEBB)

Drug Name

DOV-216419

Synonyms

Triple serotonin/dopamine/norepinephrine reuptake inhibitor (depression/pain), Dov; Triple serotonin/dopamine/norepinephrine reuptake inhibitor (depression/pain), Euthymics

Indication

Disease Entry	ICD 11	Status	REF
Attention deficit hyperactivity disorder	6A05.Z	Phase 3	[1]
Major depressive disorder	6A70.3	Investigative	[2]
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Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C15H15N
Canonical SMILES: C1C2C1(CNC2)C3=CC4=CC=CC=C4C=C3
InChI: 1S/C15H15N/c1-2-4-12-7-13(6-5-11(12)3-1)15-8-14(15)9-16-10-15/h1-7,14,16H,8-10H2/t14-,15+/m1/s1
InChIKey: HKHCSWPSUSWGLI-CABCVRRESA-N

Cross-matching ID

PubChem CID: 16095349
CAS Number: 924012-43-1
UNII: D2A6T4UH9C
DrugBank ID: DB14841
TTD ID: D0M9JJ

Repurposed Drugs (RPD)

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References

1	ClinicalTrials.gov (NCT03605849) A Trial Evaluating the Long-term Safety and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-Deficit/Hyperactivity Disorder. U.S. National Institutes of Health.
2	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.