Details of the Drug

General Information of Drug (ID: DMKGEBB)

• Drug Name: DOV-216419
• Synonyms: Triple serotonin/dopamine/norepinephrine reuptake inhibitor (depression/pain), Dov; Triple serotonin/dopamine/norepinephrine reuptake inhibitor (depression/pain), Euthymics

Indication

Disease Entry	ICD 11	Status	REF
Attention deficit hyperactivity disorder	6A05.Z	Phase 3	[1]
Major depressive disorder	6A70.3	Investigative	[2]

• Chemical Identifiers:
  Formula: C15H15N
  Canonical SMILES: C1C2C1(CNC2)C3=CC4=CC=CC=C4C=C3
  InChI: InChI=1S/C15H15N/c1-2-4-12-7-13(6-5-11(12)3-1)15-8-14(15)9-16-10-15/h1-7,14,16H,8-10H2/t14-,15+/m1/s1
  InChIKey: HKHCSWPSUSWGLI-CABCVRRESA-N
• Cross-matching ID:
  PubChem CID: 16095349
  CAS Number: 924012-43-1
  UNII: D2A6T4UH9C
  DrugBank ID: DB14841
  TTD ID: D0M9JJ
• Repurposed Drugs (RPD): Click to Jump to the Detailed RPD Information of This Drug

References

• [1] ClinicalTrials.gov (NCT03605849) A Trial Evaluating the Long-term Safety and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-Deficit/Hyperactivity Disorder. U.S. National Institutes of Health.
• [2] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.