Details of the Drug

General Information of Drug (ID: DMKJYCU)

• Drug Name: 1-biphenyl-2-ylmethanamine
• Synonyms: 2-Phenylbenzylamine; 1924-77-2; [1,1'-biphenyl]-2-ylmethanamine; 1-Biphenyl-2-Ylmethanamine; [1,1'-Biphenyl]-2-methanamine; (2-phenylphenyl)methanamine; biphenyl-2-methanamine; CHEMBL257036; (2-phenylphenyl)methylamine; 1-(biphenyl-2-yl)methanamine; biphenyl-2-ylmethanamine hydrochloride; NSC97774; 2-phenylbenzyl amine; 2-aminomethylbiphenyl; biphenyl-2-ylmethylamine; biphenyl-2-ylmethanamine; AC1Q1IHD; (2-biphenylylmethyl)amine; 2-phenylbenzylamine ,98%; 2-phenyl-phenylmethyl amine; c-biphenyl-2-yl-methylamine; SCHEMBL469051

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 183.25
  Logarithm of the Partition Coefficient (xlogp); 2.4
  Rotatable Bond Count (rotbonds); 2
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 1
• Chemical Identifiers:
  Formula: C13H13N
  IUPAC Name: (2-phenylphenyl)methanamine
  Canonical SMILES: C1=CC=C(C=C1)C2=CC=CC=C2CN
  InChI: InChI=1S/C13H13N/c14-10-12-8-4-5-9-13(12)11-6-2-1-3-7-11/h1-9H,10,14H2
  InChIKey: YHXKXVFQHWJYOD-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 263366
  ChEBI ID: CHEMBL257036
  CAS Number: 1924-77-2
  DrugBank ID: DB07412
  TTD ID: D09MVE
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Dipeptidyl peptidase 4 (DPP-4)	TTDIGC1	DPP4_HUMAN	Inhibitor	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Dipeptidyl peptidase 4 (DPP-4)	DTT	DPP4	9.54E-01	-0.27	-1.85

References

• [1] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.