Details of the Drug

General Information of Drug (ID: DMKLCRI)

Drug Name
ARC-183
Synonyms Anti-thrombin aptamer (CABG surgery), Archemix/Nuvelo
Indication
Disease Entry ICD 11 Status REF
Blood forming organ disorder JB64.1 Discontinued in Phase 1 [1]
Drug Type
Aptamer
Cross-matching ID
DrugBank ID
DB05124
TTD ID
D0W5XT

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor IIa (F2) TT6L509 THRB_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019755)
2 A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity. J Thromb Haemost. 2012 May;10(5):870-80.