Details of the Drug

General Information of Drug (ID: DMKSUOI)

Drug Name
Flavopiridol
Synonyms
FLAVO; Alvocidib [INN]; Flavopiridol hydrochloride; L 868275; HMR-1275; L-868275; L86-8275; HMR-1275, Alvocidib, L868275, Flavopiridol; (-)-cis-5,7-Dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one; 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE; 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Phase 2 [1]
Chronic lymphocytic leukaemia 2A82.0 Discontinued in Phase 3 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 401.8
Logarithm of the Partition Coefficient (xlogp) 3.3
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C21H20ClNO5
IUPAC Name
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one
Canonical SMILES
CN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O
InChI
InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1
InChIKey
BIIVYFLTOXDAOV-YVEFUNNKSA-N
Cross-matching ID
PubChem CID
5287969
ChEBI ID
CHEBI:47344
CAS Number
146426-40-6
UNII
45AD6X575G
DrugBank ID
DB03496
TTD ID
D0LF1U
VARIDT ID
DR00235
INTEDE ID
DR0079
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cyclin-dependent kinase (CDK) TTMBO1Z NOUNIPROTAC Inhibitor [3]
Cyclin-dependent kinase 9 (CDK9) TT1LVF2 CDK9_HUMAN Inhibitor [4]
Myophosphorylase (PYGM) TT31JXP PYGM_HUMAN Inhibitor [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [5]
Organic anion transporting polypeptide 1B1 (SLCO1B1) DT3D8F0 SO1B1_HUMAN Substrate [6]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
UDP-glucuronosyltransferase 1A1 (UGT1A1)
Main DME 		DEYGVN4 UD11_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [8]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [9]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Gene/Protein Processing [10]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [10]
BAG family molecular chaperone regulator 1 (BAG1) OTRQNIA4 BAG1_HUMAN Gene/Protein Processing [9]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [10]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Protein Interaction/Cellular Processes [11]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Gene/Protein Processing [12]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [13]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Protein Interaction/Cellular Processes [14]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Acute myeloid leukaemia
ICD Disease Classification 2A60
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cyclin-dependent kinase 9 (CDK9) DTT CDK9 4.38E-01 -0.04 -0.1
Breast cancer resistance protein (ABCG2) DTP BCRP 3.87E-47 -1.28E+00 -1.63E+00
Organic anion transporting polypeptide 1B1 (SLCO1B1) DTP OATP1B1 2.80E-34 1.44E-01 9.71E-01
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME UGT1A1 2.33E-02 1.75E-02 8.91E-02
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 2.5151 8.6586 -1.38 16.4309
EW-13 GDSC1 -5.0996 -2.5257 -5.109 77.2837
ES7 GDSC1 -3.7519 -1.0779 -3.788 62.7265
CADO-ES1 GDSC1 -3.3742 -1.4997 -3.3809 58.943
EW-22 GDSC1 -3.297 -0.1153 -3.409 57.1671
EW-7 GDSC1 -3.287 -1.6258 -3.2902 57.9485
HuO9 GDSC1 -3.2767 -1.1826 -3.2913 57.6591
NOS-1 [Human HNSCC] GDSC1 -3.0551 -1.8833 -3.0554 55.134
EW-18 GDSC1 -2.9772 -0.8499 -2.999 54.0324
U2OS GDSC1 -2.8586 -0.5635 -2.8949 52.5693
ES1 GDSC1 -2.7041 -0.0248 -2.7885 50.6988
SK-ES-1 GDSC1 -2.6812 -0.6225 -2.706 50.4535
NY GDSC1 -2.3948 -0.6821 -2.4073 46.9234
CHSA8926 GDSC1 -2.3664 0.2817 -2.4715 46.776
TC-71 GDSC1 -2.3323 -1.3378 -2.3326 46.1067
SK-PN-DW GDSC1 -2.3153 -1.0952 -2.3168 45.8992
ES8 GDSC1 -2.2591 0.297 -2.3588 45.4952
CAL-78 GDSC1 -2.2498 -0.1588 -2.2919 45.2238
EW-3 GDSC1 -2.2422 1.6373 -2.651 45.9292
SaOS-2 GDSC1 -2.2258 1.0178 -2.466 45.4339
HOS GDSC1 -2.097 -0.2481 -2.1244 43.2897
CAL-72 GDSC1 -2.0581 1.6807 -2.4633 43.971
HuO-3N1 GDSC1 -1.9349 -0.1406 -1.9635 41.2863
MHH-ES-1 GDSC1 -1.9315 0.6377 -2.0642 41.6913
MG-63 GDSC1 -1.8957 1.3935 -2.203 41.8986
EW-16 GDSC1 -1.844 1.231 -2.103 41.1375
ES4 GDSC1 -1.3627 2.721 -2.07 37.5069
SJSA-1 GDSC1 -1.1017 2.3506 -1.6509 33.8851
A-673 GDSC1 -0.7099 6.3177 -3.0032 36.8648
G-292 clone A141B1 GDSC1 -0.6812 3.8079 -1.8103 32.1428
ES6 GDSC1 -0.0297 5.1132 -1.7733 28.5205
EW-24 GDSC1 1.707 8.2166 -1.7863 21.395
EW-1 GDSC1 2.3762 12.1319 -3.207 25.6209
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 152 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 -3.2648 -1.4648 -3.2706 57.6337
SR GDSC1 -5.0042 -2.5833 -5.0111 76.7434
RPMI-8866 GDSC1 -4.8969 -2.2119 -4.9114 74.9757
BC-1 GDSC1 -4.815 -2.858 -4.8167 75.8061
SUP-HD1 GDSC1 -4.5933 -2.3846 -4.5987 72.8659
Ku812 GDSC1 -4.4687 -2.0723 -4.4791 71.1363
Karpas-231 GDSC1 -4.4604 -2.8861 -4.4608 72.2937
SU-DHL-8 GDSC1 -4.4262 -2.797 -4.4268 71.8284
QIMR-WIL GDSC1 -4.4063 -1.6304 -4.4324 69.7132
GA-10 GDSC1 -4.3666 -2.6773 -4.3675 71.055
SU-DHL-5 GDSC1 -4.3279 -2.8359 -4.3283 70.7773
RCH-ACV GDSC1 -4.3275 -2.4469 -4.3298 70.3683
MOLT-13 GDSC1 -4.3094 -2.2596 -4.3137 69.928
SU-DHL-16 GDSC1 -4.2794 -3.4812 -4.2794 70.4373
SUP-M2 GDSC1 -4.2698 -3.5479 -4.2698 70.3214
SU-DHL-10 GDSC1 -4.2326 -2.3769 -4.2349 69.2832
OCI-AML-2 GDSC1 -4.2203 -2.3507 -4.2227 69.1215
NU-DUL-1 GDSC1 -4.1664 -2.0537 -4.1725 68.1895
JSC-1 GDSC1 -4.0102 -1.8008 -4.0198 66.2558
VAL GDSC1 -3.9766 -0.4644 -4.0864 63.9069
MOLP-8 GDSC1 -3.9725 -2.5021 -3.9729 66.4575
SU-DHL-6 GDSC1 -3.9645 -2.0929 -3.9678 66.0797
PL-21 GDSC1 -3.8606 -1.0096 -3.9063 63.7022
NOMO-1 GDSC1 -3.8501 -1.2999 -3.876 63.9896
THP-1 GDSC1 -3.81 -2.0415 -3.8127 64.3004
NALM-6 GDSC1 -3.7752 -1.8964 -3.7794 63.8013
CTB-1 GDSC1 -3.7367 0.6079 -4.0169 60.3599
Ramos.2G6.4C10 GDSC1 -3.7106 -2.1186 -3.7119 63.1854
ST486 GDSC1 -3.706 -2.347 -3.7064 63.2127
P30/OHK GDSC1 -3.6866 -1.5342 -3.698 62.5216
OCI-Ly19 GDSC1 -3.6707 -1.8717 -3.6742 62.5896
CML-T1 GDSC1 -3.6351 -0.3335 -3.7399 60.678
CESS GDSC1 -3.6304 -2.2813 -3.6308 62.2775
SIG-M5 GDSC1 -3.6276 -2.4227 -3.6277 62.2691
DEL GDSC1 -3.627 -2.2662 -3.6274 62.2324
U-698-M GDSC1 -3.5988 -2.3495 -3.599 61.9041
Hs 445 GDSC1 -3.5932 -0.0363 -3.7386 59.9344
NB4 GDSC1 -3.5628 -2.6612 -3.5628 61.4842
NK-92MI GDSC1 -3.5261 -2.4311 -3.5262 61.0165
Jurkat GDSC1 -3.4933 -1.2567 -3.5105 60.1628
697 GDSC1 -3.4891 -2.0828 -3.4898 60.5123
TUR GDSC1 -3.487 -1.386 -3.499 60.1819
MV4-11 GDSC1 -3.4687 -2.3685 -3.4687 60.2994
BC-3 GDSC1 -3.4666 -1.9633 -3.4678 60.2104
BL-41 GDSC1 -3.4234 -2.4314 -3.4234 59.74
HC-1 GDSC1 -3.4176 -1.662 -3.4216 59.5224
P32/ISH GDSC1 -3.4033 -2.0637 -3.4038 59.4584
WIL2 NS GDSC1 -3.3922 -1.0806 -3.415 58.9132
KE-37 GDSC1 -3.3889 -1.7018 -3.3921 59.196
MY-M12 GDSC1 -3.3879 -1.9514 -3.3888 59.2503
KCL-22 GDSC1 -3.3732 -0.9081 -3.4058 58.5818
Sc-1 GDSC1 -3.3643 -0.7557 -3.408 58.3729
HAL-01 GDSC1 -3.3519 -2.4162 -3.3519 58.8477
KG-1 GDSC1 -3.323 -1.1207 -3.3417 58.1588
IM-9 GDSC1 -3.2754 -1.4153 -3.2825 57.7423
SKM-1 GDSC1 -3.2666 -1.9733 -3.267 57.7633
NKM-1 GDSC1 -3.2551 -1.8071 -3.2563 57.5998
LC4-1 GDSC1 -3.2469 -2.33 -3.2469 57.5362
RS4;11 GDSC1 -3.2317 -1.4848 -3.2366 57.2435
JJN-3 GDSC1 -3.2011 -0.9895 -3.2226 56.6961
GDM-1 GDSC1 -3.201 0.3507 -3.3832 55.8663
MOLT-4 GDSC1 -3.2002 -1.0334 -3.2194 56.7049
CA46 GDSC1 -3.1948 0.2748 -3.3625 55.8571
Karpas-299 GDSC1 -3.1788 -1.7597 -3.1799 56.6561
MLMA GDSC1 -3.1779 -1.5348 -3.1814 56.6075
SCC-3 GDSC1 -3.1643 -2.2132 -3.1643 56.5041
EB2 GDSC1 -3.1594 -0.488 -3.2173 55.9687
BALL-1 GDSC1 -3.1593 -1.022 -3.1779 56.2265
AMO1 GDSC1 -3.1437 -1.9675 -3.144 56.2401
DND-41 GDSC1 -3.1411 0.3499 -3.3182 55.2757
Karpas-422 GDSC1 -3.1244 -1.696 -3.1257 55.9792
CCRF-CEM GDSC1 -3.1186 -1.8978 -3.119 55.9246
EJM GDSC1 -3.1133 -1.6619 -3.1148 55.8379
MOLT-16 GDSC1 -3.11 -2.2258 -3.11 55.8263
DoHH2 GDSC1 -3.1037 -2.3674 -3.1037 55.7485
SU-DHL-4 GDSC1 -3.0955 -2.1396 -3.0956 55.6447
A3/Kawakami GDSC1 -3.0863 -2.4018 -3.0863 55.5301
HH [Human lymphoma] GDSC1 -3.0818 -1.1588 -3.0927 55.3575
Farage GDSC1 -3.0606 -2.1489 -3.0606 55.2088
SUP-B15 GDSC1 -3.0369 -0.9381 -3.0559 54.7619
L-363 GDSC1 -3.0285 -2.3884 -3.0285 54.8079
HL-60 GDSC1 -2.9926 -1.3447 -2.9972 54.3162
Raji GDSC1 -2.9506 -0.3903 -3.007 53.5915
Reh GDSC1 -2.9502 -1.4005 -2.9533 53.8022
TK [Human B-cell lymphoma] GDSC1 -2.9467 -0.8284 -2.9687 53.6666
MOLM-13 GDSC1 -2.9458 -2.0204 -2.9458 53.7734
H9 GDSC1 -2.9233 -0.633 -2.9571 53.3444
OCI-AML-5 GDSC1 -2.9112 -1.5072 -2.9128 53.3285
L-540 GDSC1 -2.8919 -0.7881 -2.9143 53.0058
MHH-PREB-1 GDSC1 -2.8698 -1.1812 -2.8761 52.7932
Loucy GDSC1 -2.8529 -0.5701 -2.8885 52.5037
PF-382 GDSC1 -2.8383 -1.2105 -2.8434 52.4085
ATN-1 GDSC1 -2.8372 -1.47 -2.8387 52.4091
Karpas-620 GDSC1 -2.7133 -1.5128 -2.714 50.8675
OCI-AML-3 GDSC1 -2.6917 -1.7411 -2.6918 50.5984
SUP-T1 GDSC1 -2.6796 -1.06 -2.6857 50.4425
ML-2 GDSC1 -2.6768 -1.0225 -2.6839 50.4084
Karpas-45 GDSC1 -2.6724 -1.1793 -2.6761 50.3554
RPMI-6666 GDSC1 -2.6675 -0.2337 -2.7246 50.2799
Mono-Mac-6 GDSC1 -2.6653 -0.0329 -2.746 50.2493
KOPN-8 GDSC1 -2.6624 -1.6522 -2.6625 50.2312
MC116 GDSC1 -2.6279 -1.5491 -2.6282 49.8009
RPMI-8402 GDSC1 -2.6084 -1.2964 -2.61 49.5584
BV-173 GDSC1 -2.5856 -1.4924 -2.5859 49.2719
HT GDSC1 -2.5211 -0.9776 -2.5267 48.4757
YT GDSC1 -2.5201 -1.4123 -2.5206 48.4545
SU-DHL-1 GDSC1 -2.4612 -1.7445 -2.4612 47.7165
EM-2 GDSC1 -2.436 1.391 -2.7919 47.8773
OPM-2 GDSC1 -2.4151 -0.7274 -2.4263 47.1717
DB GDSC1 -2.3955 -0.8761 -2.4015 46.9148
P12-Ichikawa GDSC1 -2.3902 -1.2055 -2.3912 46.8334
Jiyoye GDSC1 -2.3837 0.0461 -2.4564 46.9192
KMOE-2 GDSC1 -2.379 0.3504 -2.4961 46.9449
LAMA-84 GDSC1 -2.2763 -0.523 -2.293 45.4685
ALL-SIL GDSC1 -2.2549 -0.9092 -2.2582 45.1526
L-1236 GDSC1 -2.2164 1.7792 -2.6659 45.7302
MEG-01 GDSC1 -2.1997 -0.0646 -2.2485 44.6319
KMS-12-BM GDSC1 -2.1995 -1.5493 -2.1995 44.4457
ROS-50 GDSC1 -2.1718 1.948 -2.6705 45.3584
KY821 GDSC1 -2.1402 0.0934 -2.2034 43.955
ME1 GDSC1 -2.1307 0.0315 -2.186 43.8114
RPMI-8226 GDSC1 -2.0505 -0.2808 -2.0736 42.6949
RC-K8 GDSC1 -2.0125 2.6927 -2.7556 44.2394
U266B1 GDSC1 -2.0122 1.2293 -2.2859 43.1125
MN-60 GDSC1 -1.9936 1.9452 -2.4759 43.4737
CTV-1 GDSC1 -1.9864 2.2562 -2.5718 43.6448
GR-ST GDSC1 -1.7865 1.421 -2.0915 40.6454
L-428 GDSC1 -1.7332 -0.0535 -1.7596 38.768
BE-13 GDSC1 -1.725 0.3271 -1.7915 38.877
K-562 GDSC1 -1.7105 0.0133 -1.7413 38.5091
HDLM-2 GDSC1 -1.6486 -0.1553 -1.6647 37.6549
HEL GDSC1 -1.6133 -0.1531 -1.6284 37.2091
ALL-PO GDSC1 -1.5444 -0.5123 -1.5464 36.2692
RL GDSC1 -1.304 4.4528 -2.7319 39.3663
DG-75 GDSC1 -1.1798 2.8317 -1.9184 35.663
Daudi GDSC1 -1.1543 3.3058 -2.0836 36.2044
JVM-3 GDSC1 -0.8856 5.4954 -2.7865 37.1299
KM-H2 GDSC1 -0.8737 1.5665 -1.1379 29.5459
WSU-DLCL2 GDSC1 -0.7608 2.9375 -1.5186 31.0975
JURL-MK1 GDSC1 -0.7406 2.9303 -1.4944 30.846
LP-1 GDSC1 -0.6815 5.1609 -2.4291 34.8015
SK-MM-2 GDSC1 -0.6757 6.2173 -2.9224 36.4482
WSU-NHL GDSC1 -0.5516 4.9003 -2.1793 33.1054
EHEB GDSC1 -0.3092 6.8229 -2.8646 34.4639
ARH-77 GDSC1 -0.072 3.3045 -0.9664 23.9793
OCI-M1 GDSC1 -0.0523 3.1818 -0.8912 23.3781
Granta-519 GDSC1 0.0861 5.5842 -1.8913 28.5599
KMS-11 GDSC1 0.3386 6.7547 -2.2319 29.0153
EoL-1 GDSC1 0.6812 4.7837 -0.9482 20.3182
P31/FUJ GDSC1 0.9927 8.8181 -2.6819 28.2552
JVM-2 GDSC1 4.2324 6.4052 0.6441 0.6564
VL51 GDSC1 4.7324 14.7276 -2.7684 17.6592
⏷ Show the Full List of 152 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1 -3.2339 0.8141 -3.5162 55.8473
FLO-1 GDSC1 -2.4374 -0.1735 -2.4881 47.5246
OACP4 C GDSC1 -2.2269 0.9162 -2.4434 45.3951
KYSE-50 GDSC1 -2.085 2.9344 -2.9234 45.0929
KYSE-220 GDSC1 -1.7625 0.9004 -1.9346 39.8292
HCE-4 GDSC1 -1.0933 1.414 -1.333 32.0846
TE-12 GDSC1 0.3517 6.9226 -2.3029 29.2733
KYAE-1 GDSC1 0.6294 8.7303 -2.9528 30.7087
OACM5.1 C GDSC1 1.076 8.0303 -2.2171 25.9034
SK-GT-4 GDSC1 2.1174 8.3978 -1.5521 18.6947
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 -1.4495 4.3159 -2.821 40.5061
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB1 GDSC1 -4.6481 0.6365 -5.0149 66.5511
NB69 GDSC1 -4.1317 -0.4098 -4.2595 65.0812
KP-N-YS GDSC1 -3.7767 -1.4971 -3.7913 63.4591
SJNB-14 GDSC1 -3.737 -0.5004 -3.827 61.8391
NB(TU)1 GDSC1 -3.6038 0.1571 -3.7829 59.8017
GOTO GDSC1 -3.3926 1.1389 -3.7686 56.9727
IMR-5 GDSC1 -3.3763 -0.8717 -3.4116 58.5892
SK-N-MC-IXC GDSC1 -3.1647 -1.4549 -3.1694 56.4291
SJNB-5 GDSC1 -3.1222 -1.7631 -3.123 55.9583
SJNB-10 GDSC1 -3.1101 1.0228 -3.4312 54.577
Kelly GDSC1 -3.0637 -1.4493 -3.0673 55.2004
TGW GDSC1 -3.0271 -1.1486 -3.0372 54.6999
SJNB-7 GDSC1 -2.884 1.3783 -3.2773 52.3231
SK-N-SH GDSC1 -2.8833 0.301 -3.031 52.6357
CHP-212 GDSC1 -2.7548 1.4914 -3.1679 51.0758
SiMa GDSC1 -2.6087 1.0896 -2.901 49.6348
SJNB-6 GDSC1 -2.5881 3.2626 -3.5861 49.5565
SK-N-FI GDSC1 -2.4594 -0.3906 -2.4916 47.7598
SJNB-13 GDSC1 -2.2978 1.5112 -2.6749 46.4613
GI-ME-N GDSC1 -2.2126 2.4539 -2.8853 46.0387
NH-12 GDSC1 -2.1584 3.2752 -3.1326 45.9478
MHH-NB-11 GDSC1 -2.1579 1.3499 -2.4772 44.854
SJNB-12 GDSC1 -2.1242 1.0866 -2.372 44.3077
KP-N-YN GDSC1 -1.8209 3.4437 -2.8416 43.0111
CHP-134 GDSC1 -1.7979 1.6537 -2.1716 41.0211
SK-N-BE(2)-M17 GDSC1 -1.7786 3.0882 -2.6555 42.285
SK-N-AS GDSC1 -1.7195 1.3875 -2.009 39.812
LA-N-6 GDSC1 -1.2054 1.8958 -1.6033 34.3107
SK-N-DZ GDSC1 -0.8257 4.8927 -2.4476 35.6592
SJNB-17 GDSC1 1.699 11.2465 -3.3063 28.1173
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 -1.8299 1.8909 -2.2803 41.6284
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1599 GDSC1 -3.8978 -2.3 -3.8989 65.4753
HCC1187 GDSC1 -3.7706 -2.0985 -3.7725 63.8806
DU4475 GDSC1 -3.4906 -2.6391 -3.4906 60.5831
HCC70 GDSC1 -3.3238 -1.797 -3.3255 58.437
MCF-7 GDSC1 -3.2164 -0.8533 -3.2466 56.8028
AU565 GDSC1 -3.0664 -1.1514 -3.0772 55.1713
HCC1806 GDSC1 -2.9906 -0.8202 -3.0145 54.1826
COLO 824 GDSC1 -2.889 -1.0148 -2.9007 53.0074
HCC2157 GDSC1 -2.8206 -0.7026 -2.8456 52.1404
MDA-MB-468 GDSC1 -2.7764 -0.7414 -2.7975 51.6126
MRK-nu-1 GDSC1 -2.665 1.3288 -3.0248 50.2112
HCC2218 GDSC1 -2.418 1.6376 -2.8429 47.7584
MFM-223 GDSC1 -2.3946 -0.7106 -2.406 46.9185
MDA-MB-157 GDSC1 -2.3171 -0.5403 -2.3341 45.9746
EFM-19 GDSC1 -2.274 2.2854 -2.8933 46.5555
HCC1954 GDSC1 -2.2688 2.1254 -2.8338 46.4342
BT-20 GDSC1 -2.1332 0.3351 -2.2295 43.9804
OCUB-M GDSC1 -2.022 2.8657 -2.8301 44.4532
UACC-893 GDSC1 -1.8008 2.1889 -2.3478 41.6129
HCC38 GDSC1 -1.4416 0.6047 -1.5296 35.4914
HCC1569 GDSC1 -1.2172 5.6409 -3.1825 40.0346
HCC1500 GDSC1 -1.2006 0.4563 -1.2498 32.2649
HCC1395 GDSC1 -1.0288 3.5247 -2.0448 35.2631
CAMA-1 GDSC1 -0.8937 3.743 -1.9993 34.2531
UACC-812 GDSC1 -0.8854 4.6398 -2.3915 35.7889
BT-474 GDSC1 -0.7416 5.8613 -2.8172 36.4595
MDA-MB-330 GDSC1 -0.6398 5.4283 -2.5136 34.8917
EFM-192A GDSC1 -0.6189 4.876 -2.2344 33.6974
MDA-MB-231 GDSC1 -0.519 7.657 -3.4669 37.22
HCC202 GDSC1 -0.4163 6.4734 -2.7966 34.7501
BT-549 GDSC1 -0.1313 4.7735 -1.7087 28.689
MDA-MB-453 GDSC1 0.0099 7.5925 -2.9445 33.2727
HCC1428 GDSC1 0.28 3.9932 -0.9396 22.0725
CAL-148 GDSC1 0.3856 5.6001 -1.6205 25.7484
HDQ-P1 GDSC1 0.4895 8.7466 -3.084 31.7295
HCC1419 GDSC1 0.731 7.4349 -2.2188 27.2851
ZR-75-30 GDSC1 0.8159 8.8805 -2.8652 29.6534
BT-483 GDSC1 0.9243 8.8789 -2.7709 28.8718
MDA-MB-415 GDSC1 0.9806 7.5409 -2.0545 25.4945
Hs 578T GDSC1 1.0998 11.332 -3.847 31.8666
CAL-120 GDSC1 1.1125 9.229 -2.7851 28.218
YMB-1-E GDSC1 1.1723 7.6018 -1.9212 24.0744
Evsa-T GDSC1 2.2511 5.4681 -0.0102 7.8919
T-47D GDSC1 2.4092 14.8076 -4.5134 29.696
CAL-51 GDSC1 2.4426 16.8874 -5.5237 32.0451
MDA-MB-361 GDSC1 3.2558 9.8818 -1.4461 14.7066
MDA-MB-175-VII GDSC1 3.3812 14.3011 -3.516 23.9254
CAL-85-1 GDSC1 3.4006 12.0227 -2.3842 19.2138
HCC1937 GDSC1 3.6758 13.5501 -2.9324 20.9037
MDA-MB-436 GDSC1 4.2804 18.0428 -4.6933 25.4937
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med GDSC1 -3.5547 -0.5902 -3.6237 60.1948
PFSK-1 GDSC1 -3.2475 -0.3986 -3.3199 56.8646
D-566MG GDSC1 -2.7442 -0.7915 -2.7617 51.2269
D-336MG GDSC1 -2.65 -0.8225 -2.6633 50.0754
GI-1 GDSC1 -2.6054 -0.3208 -2.6505 49.5398
D-392MG GDSC1 -2.5349 -0.4614 -2.565 48.6766
MOG-G-CCM GDSC1 -2.524 -0.3486 -2.5626 48.5536
SF268 GDSC1 -2.3466 1.9049 -2.8469 47.1214
D-423MG GDSC1 -2.3183 -0.7379 -2.327 45.9633
MOG-G-UVW GDSC1 -2.2712 0.4022 -2.3887 45.6814
SNB-75 GDSC1 -2.2069 -0.1918 -2.2438 44.6809
U-251MG GDSC1 -2.1825 0.9047 -2.3924 44.8749
DK-MG GDSC1 -2.0679 2.1215 -2.6145 44.3907
GB-1 GDSC1 -2.0672 0.3028 -2.1539 43.1525
D-263MG GDSC1 -2.0614 0.6924 -2.2155 43.3122
SF539 GDSC1 -2.0229 -0.7929 -2.0256 42.253
8-MG-BA GDSC1 -1.9417 0.9932 -2.1506 42.093
KS-1 [Human Krukenberg tumour] GDSC1 -1.8406 2.5009 -2.5007 42.3456
M059J GDSC1 -1.7887 1.9074 -2.2409 41.185
Daoy GDSC1 -1.758 0.6253 -1.8744 39.5243
SK-MG-1 GDSC1 -1.7151 2.8702 -2.5035 41.431
Onda 10 GDSC1 -1.6631 0.1084 -1.7004 37.9555
YKG-1 GDSC1 -1.6318 3.6339 -2.7202 41.4286
YH-13 GDSC1 -1.5431 1.3786 -1.8141 37.6654
ONS-76 GDSC1 -1.5217 3.4164 -2.515 40.1237
SF126 GDSC1 -1.4604 3.7125 -2.5737 39.8925
GaMG GDSC1 -1.3722 1.2358 -1.5894 35.3497
H4 GDSC1 -1.3262 0.278 -1.3623 33.7517
LN-18 GDSC1 -1.3115 2.2985 -1.8576 36.2564
SW1088 GDSC1 -1.2121 1.3911 -1.4563 33.5571
D-542MG GDSC1 -1.1766 3.9738 -2.3911 37.5078
SW1783 GDSC1 -0.9562 2.4018 -1.514 32.2496
42-MG-BA GDSC1 -0.911 1.7529 -1.2368 30.3789
KALS-1 GDSC1 -0.8721 3.6311 -1.9284 33.8079
D-247MG GDSC1 -0.7674 4.1226 -2.0385 33.6909
CAS-1 GDSC1 -0.7592 4.3201 -2.1192 33.9927
NMC-G1 GDSC1 -0.6599 8.1988 -3.8625 38.7948
Hs 683 GDSC1 -0.5776 2.0884 -0.9913 26.8752
AM-38 GDSC1 -0.3421 6.3233 -2.6537 33.8888
LNZTA3WT4 GDSC1 -0.3012 3.2968 -1.1958 26.6415
Becker GDSC1 -0.1204 6.538 -2.5489 32.4349
LN-229 GDSC1 -0.1067 3.0426 -0.8847 23.6135
U-118MG GDSC1 0.0598 5.596 -1.9218 28.836
D-502MG GDSC1 0.3254 4.6891 -1.2316 23.7439
LN-405 GDSC1 0.3347 5.5623 -1.6489 26.1361
KINGS-1 GDSC1 0.5412 6.135 -1.7423 25.7191
DBTRG-05MG GDSC1 0.6477 7.36 -2.2549 27.795
A-172 GDSC1 1.194 6.4943 -1.3492 20.7829
SF295 GDSC1 1.5395 5.6721 -0.651 14.877
Onda 11 GDSC1 2.3881 10.7018 -2.487 22.6138
KNS-81-FD GDSC1 2.4603 8.2937 -1.2409 15.7554
KNS-42 GDSC1 2.4997 7.8881 -1.0128 14.1988
U-87MG ATCC GDSC1 3.6711 15.1637 -3.7262 23.9193
T98G GDSC1 4.4543 14.7721 -2.9784 19.1818
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 -2.556 1.3464 -2.9106 49.1107
TGBC1TKB GDSC1 0.0096 6.2733 -2.2985 30.8046
TGBC24TKB GDSC1 2.2046 8.2763 -1.4248 17.6677
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA GDSC1 -3.818 -1.7643 -3.8253 64.1677
RL95-2 GDSC1 -2.9599 -1.1177 -2.9696 53.8832
ESS-1 GDSC1 -2.2519 1.2034 -2.5407 45.82
MFE-296 GDSC1 -2.2442 2.0058 -2.7678 46.1312
EN GDSC1 -2.1419 0.015 -2.196 43.9436
MFE-319 GDSC1 -1.652 1.594 -1.9946 39.2479
KLE GDSC1 -1.083 5.6266 -3.0426 38.9426
MFE-280 GDSC1 -0.1101 3.7025 -1.1861 25.5829
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC1 -3.5031 -1.1638 -3.5251 60.2
786-O GDSC1 -3.1903 -0.4823 -3.2504 56.3034
769-P GDSC1 -3.0489 0.0353 -3.1657 54.5028
RXF 393L GDSC1 -2.932 0.5255 -3.1258 53.0737
A-704 GDSC1 -2.5643 -0.0138 -2.641 49.0673
UO-31 GDSC1 -2.3693 1.9683 -2.8918 47.3689
KTCTL-195 GDSC1 -2.316 0.2397 -2.411 46.1594
VMRC-RCZ GDSC1 -2.2633 1.6972 -2.692 46.1807
KTCTL-21 GDSC1 -2.1345 1.2736 -2.4311 44.5442
KTCTL-26A GDSC1 -1.9568 2.9027 -2.7743 43.8545
SN12C GDSC1 -1.6974 2.8168 -2.4642 41.1925
SW13 GDSC1 -1.6797 0.0472 -1.7121 38.1346
KTCTL-13 GDSC1 -1.5859 2.4946 -2.2243 39.6307
KTCTL-1M GDSC1 -1.4142 0.6249 -1.5036 35.16
BB65-RCC GDSC1 -1.39 4.4493 -2.8184 40.1308
KMRC-1 GDSC1 -1.309 4.0764 -2.572 38.9225
BFTC-909 GDSC1 -0.9729 4.1583 -2.2634 35.812
VMRC-RCW GDSC1 -0.728 2.9449 -1.4872 30.7328
NCC021 GDSC1 -0.7026 5.3278 -2.5279 35.2779
SW156 GDSC1 -0.6734 5.1245 -2.404 34.6627
CAL-54 GDSC1 -0.4845 4.6229 -1.9839 31.8806
LB1047-RCC GDSC1 -0.4561 8.2781 -3.7109 37.5415
RCC10RGB GDSC1 -0.3711 8.3187 -3.6519 37.0235
TK-10 GDSC1 -0.2522 7.4203 -3.1022 34.9631
ACHN GDSC1 0.0835 4.7671 -1.4989 26.4816
Caki-1 GDSC1 0.168 6.0989 -2.066 29.0221
KMRC-20 GDSC1 0.1985 8.3337 -3.1388 33.1071
HA7-RCC GDSC1 0.2021 4.2142 -1.1203 23.6245
LB2241-RCC GDSC1 0.5702 9.8447 -3.5597 32.9339
LB996-RCC GDSC1 1.19 9.8595 -3.0348 28.8894
OS-RC-2 GDSC1 1.2092 12.7148 -4.4461 33.1079
A-498 GDSC1 3.7004 13.8671 -3.0695 21.3993
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 GDSC1 -4.1098 0.6725 -4.4372 63.056
LS411N GDSC1 -3.4144 0.2819 -3.6011 57.9532
NCI-H716 GDSC1 -3.2646 0.0127 -3.3935 56.7415
COLO 320HSR GDSC1 -3.1724 -1.1111 -3.1873 56.4139
HCT 116 GDSC1 -3.1604 -1.5873 -3.163 56.4042
SNU-407 GDSC1 -3.0386 0.2544 -3.1904 54.2889
SNU-C1 GDSC1 -3.0059 0.7116 -3.245 53.743
KM12 GDSC1 -2.6919 1.2815 -3.0415 50.482
COLO205 GDSC1 -2.4927 0.6306 -2.6707 48.3246
CCK-81 GDSC1 -2.4304 -1.1634 -2.432 47.337
SNU-C2B GDSC1 -2.3337 2.0749 -2.8876 47.0547
LS513 GDSC1 -2.2784 3.3565 -3.2921 47.0217
CaR-1 GDSC1 -2.1977 1.9003 -2.6835 45.6003
SNU-1040 GDSC1 -1.9445 1.0147 -2.1588 42.1447
HCC2998 GDSC1 -1.7144 1.4475 -2.0202 39.8188
RKO GDSC1 -1.6822 -0.0488 -1.7067 38.1217
HT115 GDSC1 -1.6724 2.6433 -2.3721 40.7373
HT-29 GDSC1 -1.5393 3.1386 -2.4214 39.9567
GP5d GDSC1 -1.5246 -0.2423 -1.5329 36.0604
NCI-H747 GDSC1 -1.5048 2.5016 -2.1397 38.7519
SNU-175 GDSC1 -1.4392 1.1455 -1.6396 36.0723
SW620 GDSC1 -1.2321 3.4818 -2.2385 37.304
LoVo GDSC1 -0.9379 5.6407 -2.9058 37.772
SNU-61 GDSC1 -0.6325 5.6679 -2.6195 35.2317
CL-11 GDSC1 -0.5362 4.823 -2.1281 32.8031
LS180 GDSC1 -0.4734 6.4403 -2.835 35.1581
LS1034 GDSC1 -0.3356 5.9078 -2.4475 33.0824
MDST8 GDSC1 -0.2419 5.5508 -2.1865 31.5363
COLO 678 GDSC1 -0.1751 5.677 -2.1833 31.1917
HT-55 GDSC1 -0.077 5.9528 -2.2237 30.8918
SNU-C5 GDSC1 0.0167 6.5364 -2.4203 31.282
RCM-1 [Human ESC] GDSC1 0.1868 9.1934 -3.5751 34.4765
SW626 GDSC1 0.4516 6.3929 -1.9508 27.1864
SW837 GDSC1 0.7332 6.3083 -1.6564 24.4291
SW1463 GDSC1 0.8199 8.7317 -2.7875 29.3402
T84 GDSC1 0.9513 8.2602 -2.4388 27.3916
SW48 GDSC1 1.6007 11.808 -3.6674 29.6484
LS123 GDSC1 1.659 10.2417 -2.8369 26.4824
SW1116 GDSC1 1.761 8.3436 -1.8062 21.3134
SW1417 GDSC1 1.7845 8.3721 -1.8016 21.2069
SW948 GDSC1 1.7938 7.1127 -1.166 17.4492
HCT 15 GDSC1 2.2206 8.0436 -1.2973 16.8497
CW-2 GDSC1 3.7816 5.7561 0.7036 0.7311
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 -2.2484 1.4528 -2.6044 45.9041
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-423 GDSC1 -2.5482 0.5425 -2.7134 48.9355
HLE GDSC1 -2.398 0.103 -2.4791 47.1054
SNU-475 GDSC1 -2.3653 -0.3256 -2.3984 46.6119
JHH-1 GDSC1 -2.2829 -0.2562 -2.3179 45.6077
SNU-387 GDSC1 -1.8715 1.5965 -2.2347 41.809
SNU-398 GDSC1 -1.8688 -0.8083 -1.87 40.3186
Hep 3B2.1-7 GDSC1 -1.8482 8.2103 -5.0057 45.9203
JHH-7 GDSC1 -1.3512 3.4511 -2.3503 38.4702
SK-HEP-1 GDSC1 -1.2992 2.8717 -2.0609 37.0473
JHH-4 GDSC1 -0.9486 3.7304 -2.0504 34.8015
JHH-2 GDSC1 -0.8954 3.8375 -2.0425 34.4516
Huh-7 GDSC1 -0.2851 9.4987 -4.1525 37.8152
SNU-449 GDSC1 -0.0727 6.929 -2.6953 32.764
JHH-6 GDSC1 0.1323 7.2268 -2.6525 31.6768
Hep-G2/C3A GDSC1 1.38 8.0801 -1.986 23.6222
HuH-1 GDSC1 1.868 10.3082 -2.7008 25.2197
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SBC-3 GDSC1 -3.9909 -1.7514 -4.0016 65.9947
IST-SL2 GDSC1 -3.873 -1.1403 -3.9095 64.0033
NCI-H290 GDSC1 -3.7409 -2.5073 -3.741 63.6739
LCLC-97TM1 GDSC1 -3.56 -1.1031 -3.5872 60.7635
EPLC-272H GDSC1 -3.2271 -2.1861 -3.2272 57.2866
NCI-H847 GDSC1 -3.1332 -1.4484 -3.1376 56.0463
COR-L23 GDSC1 -2.9867 1.7757 -3.5042 53.1137
HCC78 GDSC1 -2.975 -0.6477 -3.0099 53.9513
UMC-11 GDSC1 -2.9661 -0.1798 -3.0474 53.6955
NCI-H524 GDSC1 -2.9556 -0.7731 -2.9811 53.7582
HCC827 GDSC1 -2.8923 1.1474 -3.225 52.4704
NCI-H1581 GDSC1 -2.8719 -0.6311 -2.9037 52.7388
NCI-H2803 GDSC1 -2.8667 0.9886 -3.1575 52.2677
COR-L311 GDSC1 -2.81 -1.5008 -2.8111 52.0716
NCI-H510A GDSC1 -2.803 -0.9011 -2.8171 51.9506
LK-2 GDSC1 -2.8018 -1.4032 -2.8037 51.967
NCI-H64 GDSC1 -2.7793 -2.0893 -2.7793 51.6932
NCI-H810 GDSC1 -2.7628 -0.0792 -2.8438 51.3778
NCI-H1648 GDSC1 -2.7476 -0.2034 -2.8127 51.2176
A-427 GDSC1 -2.6871 -0.3972 -2.7293 50.5176
NCI-H1436 GDSC1 -2.6861 0.529 -2.8601 50.4632
NCI-H1048 GDSC1 -2.6793 -0.6411 -2.7029 50.4308
Lu-99A GDSC1 -2.6707 0.8826 -2.9188 50.2832
DMS 273 GDSC1 -2.51 -1.19 -2.5119 48.3314
NCI-H1105 GDSC1 -2.4512 -0.9106 -2.4573 47.6081
NCI-H82 GDSC1 -2.4487 -0.9425 -2.454 47.5747
ABC-1 GDSC1 -2.4312 0.2225 -2.5319 47.53
HOP-62 GDSC1 -2.4246 1.3462 -2.7671 47.7456
NCI-H211 GDSC1 -2.413 -0.4799 -2.4369 47.1753
NCI-H526 GDSC1 -2.4064 -1.2211 -2.4074 47.0351
NCI-H2347 GDSC1 -2.3805 1.8697 -2.8727 47.4483
CAL-12T GDSC1 -2.302 2.5015 -2.9986 46.9116
NCI-H292 GDSC1 -2.2524 -0.6433 -2.2629 45.1499
NCI-H661 GDSC1 -2.2419 0.281 -2.3378 45.2805
NCI-H460 GDSC1 -2.2412 0.0147 -2.3012 45.1726
Lu-135 GDSC1 -2.2244 -0.9063 -2.2274 44.7708
SHP-77 GDSC1 -2.1434 -1.0901 -2.1441 43.7482
NCI-H1155 GDSC1 -2.1264 0.6301 -2.2737 44.0568
NCI-H647 GDSC1 -2.1195 0.1107 -2.1835 43.7055
NCI-H1563 GDSC1 -2.1177 10.5286 -6.3707 47.8035
NCI-H520 GDSC1 -2.0779 1.4438 -2.4159 44.0213
NCI-H2171 GDSC1 -2.0765 -0.3081 -2.0988 43.0137
NCI-H1651 GDSC1 -2.0743 -0.1552 -2.108 43.0347
NCI-H1792 GDSC1 -2.0633 -0.9043 -2.065 42.7526
CPC-N GDSC1 -2.0574 1.4505 -2.3953 43.7954
NCI-H1944 GDSC1 -2.054 3.0661 -2.9405 44.8869
NCI-H2135 GDSC1 -2.0443 1.3425 -2.3512 43.568
NCI-H1304 GDSC1 -2.012 1.3982 -2.3312 43.2418
NCI-H23 GDSC1 -1.9932 -0.4496 -2.005 41.9292
LCLC-103H GDSC1 -1.9813 2.2646 -2.5693 43.5995
NCI-H1781 GDSC1 -1.9801 1.8703 -2.4371 43.2663
NCI-H1876 GDSC1 -1.9703 0.7192 -2.1222 42.2268
NCI-H1568 GDSC1 -1.9235 0.8944 -2.1083 41.7929
EMC-BAC-2 GDSC1 -1.9076 0.1294 -1.9608 41.0643
NCI-H1770 GDSC1 -1.9011 1.4668 -2.2294 42.0282
NCI-H1694 GDSC1 -1.8817 0.5625 -1.9967 41.0196
HARA [Human squamous cell lung carcinoma] GDSC1 -1.8797 -0.0402 -1.9141 40.6297
NCI-H226 GDSC1 -1.8782 1.5788 -2.2369 41.8698
NCI-H3122 GDSC1 -1.8643 1.6818 -2.2525 41.8098
PaCa-3 GDSC1 -1.8193 2.7986 -2.5878 42.412
NCI-H1623 GDSC1 -1.8103 0.8697 -1.9799 40.3903
NCI-H146 GDSC1 -1.7892 3.0839 -2.6652 42.3847
NCI-H2030 GDSC1 -1.7732 0.0731 -1.8128 39.3354
LXF 289 GDSC1 -1.77 2.0112 -2.2545 41.086
NCI-H2869 GDSC1 -1.7315 3.6764 -2.8423 42.3949
NCI-H2795 GDSC1 -1.7087 2.6672 -2.42 41.1447
NCI-H2029 GDSC1 -1.673 0.9111 -1.8397 38.73
NCI-H2722 GDSC1 -1.6674 2.294 -2.2401 40.2738
NCI-H1703 GDSC1 -1.6649 1.1038 -1.8754 38.8336
IA-LM GDSC1 -1.6589 2.5983 -2.3409 40.5423
NCI-H2141 GDSC1 -1.655 2.3544 -2.248 40.2101
PC-14 GDSC1 -1.6447 0.8088 -1.7872 38.2719
Ms-1 GDSC1 -1.6415 0.8348 -1.7891 38.2581
SBC-5 GDSC1 -1.6095 -0.1264 -1.6259 37.1688
COR-L321 GDSC1 -1.6044 0.0537 -1.6336 37.1792
LC-2/ad GDSC1 -1.5803 3.7519 -2.7154 41.0731
LB647-SCLC GDSC1 -1.5662 0.9125 -1.7238 37.3932
NCI-H187 GDSC1 -1.5519 2.2682 -2.1063 38.9586
NCI-H1437 GDSC1 -1.5453 1.4181 -1.8275 37.7436
HCC44 GDSC1 -1.542 2.0536 -2.0213 38.5549
RERF-LC-KJ GDSC1 -1.5191 0.3963 -1.5813 36.3057
NCI-H1734 GDSC1 -1.5065 4.6521 -3.0269 41.3603
KNS-62 GDSC1 -1.371 2.7272 -2.0813 37.6078
NCI-H2818 GDSC1 -1.3668 0.9124 -1.5071 34.8632
NCI-H841 GDSC1 -1.344 0.4322 -1.3993 34.0889
EKVX GDSC1 -1.3211 2.6309 -1.9912 36.905
ChaGo-K-1 GDSC1 -1.3001 0.59 -1.3752 33.661
NCI-H2110 GDSC1 -1.2911 2.7571 -2.0076 36.7739
COR-L88 GDSC1 -1.2696 2.6865 -1.9574 36.4186
COLO 668 GDSC1 -1.2653 1.125 -1.445 33.841
Lu-139 GDSC1 -1.262 1.6216 -1.5778 34.5497
RERF-LC-MS GDSC1 -1.2125 0.2615 -1.241 32.2854
NCI-H2087 GDSC1 -1.195 4.3983 -2.5964 38.3005
NCI-H720 GDSC1 -1.1896 2.7036 -1.8787 35.5481
NCI-H2081 GDSC1 -1.1741 1.9586 -1.5904 34.0383
SW1271 GDSC1 -1.1664 3.4382 -2.1516 36.554
NCI-H1975 GDSC1 -1.1526 2.5862 -1.7941 34.9169
NCI-H209 GDSC1 -1.1014 7.5778 -3.9821 41.0829
Calu-6 GDSC1 -1.0988 3.9878 -2.3171 36.7676
NCI-H322M GDSC1 -1.0577 4.3236 -2.4233 36.9037
NCI-H69 GDSC1 -1.005 4.4192 -2.4125 36.5549
NCI-H1341 GDSC1 -0.9829 3.8199 -2.1247 35.319
NCI-H446 GDSC1 -0.9214 3.5848 -1.9592 34.24
COR-L303 GDSC1 -0.8943 3.1647 -1.7528 33.1085
NCI-H727 GDSC1 -0.8588 4.422 -2.2658 35.1584
COR-L105 GDSC1 -0.8382 3.1534 -1.6893 32.4552
Lu-134-A GDSC1 -0.8287 2.8792 -1.566 31.7561
HCC33 GDSC1 -0.8057 5.5566 -2.7365 36.5411
NCI-H1836 GDSC1 -0.7978 3.6705 -1.8691 33.0965
Lu-65 GDSC1 -0.7609 4.1432 -2.0412 33.666
NCI-H441 GDSC1 -0.729 4.6015 -2.2172 34.2309
NCI-H1299 GDSC1 -0.7269 4.4913 -2.1646 34.0024
NCI-H2595 GDSC1 -0.7123 2.7502 -1.3909 30.0983
NCI-H2444 GDSC1 -0.7034 8.8212 -4.2064 39.6811
IST-SL1 GDSC1 -0.6944 4.8 -2.2741 34.2705
Calu-3 GDSC1 -0.6841 5.5765 -2.6267 35.5279
NCI-H2196 GDSC1 -0.6721 4.1483 -1.9536 32.7698
NCI-H650 GDSC1 -0.6602 4.3263 -2.0224 33.0149
NCI-H1573 GDSC1 -0.5647 3.7206 -1.6528 30.6911
NCI-H2170 GDSC1 -0.5511 6.9592 -3.1591 36.5344
SBC-1 GDSC1 -0.5197 3.4069 -1.468 29.438
DMS 114 GDSC1 -0.5128 3.0856 -1.3219 28.5581
NCI-H2369 GDSC1 -0.5128 1.8769 -0.8461 25.5557
BEN GDSC1 -0.5034 4.434 -1.915 31.6602
NCI-H1869 GDSC1 -0.4973 3.5921 -1.5269 29.6415
NCI-H1355 GDSC1 -0.4563 3.6337 -1.5037 29.2874
NCI-H2085 GDSC1 -0.4441 5.1143 -2.1743 32.5155
NCI-H2373 GDSC1 -0.405 5.6056 -2.3695 33.1229
NCI-H2810 GDSC1 -0.3085 4.1782 -1.6031 29.039
NCI-H522 GDSC1 -0.1852 1.9171 -0.5068 21.4308
EBC-1 GDSC1 -0.1696 5.2095 -1.9535 30.1091
DMS 53 GDSC1 -0.1668 4.2062 -1.476 27.5989
NCI-H2172 GDSC1 -0.1399 2.2087 -0.5686 21.6162
NCI-H596 GDSC1 -0.1318 2.486 -0.672 22.2925
NCI-H345 GDSC1 -0.018 7.4816 -2.9156 33.2979
NCI-H2342 GDSC1 0.1581 5.071 -1.5746 26.549
NCI-H1688 GDSC1 0.2322 3.4448 -0.7271 20.8458
NCI-H2066 GDSC1 0.2614 4.3905 -1.148 23.5187
NCI-H1666 GDSC1 0.331 7.1252 -2.4217 29.8748
NCI-H2461 GDSC1 0.3492 7.797 -2.7376 31.0597
NCI-H513 GDSC1 0.3541 5.8606 -1.7774 26.7358
NCI-H838 GDSC1 0.4173 5.3433 -1.4653 24.7264
NCI-H358 GDSC1 0.4379 8.8739 -3.193 32.3027
NCI-H2731 GDSC1 0.4913 7.3851 -2.4063 29.1205
NCI-H1793 GDSC1 0.5076 5.4977 -1.4583 24.2814
SW1573 GDSC1 0.5123 5.5391 -1.4744 24.3534
NCI-H2009 GDSC1 0.5495 6.7669 -2.0477 27.2368
NCI-H2591 GDSC1 0.8019 7.728 -2.3027 27.3802
SK-MES-1 GDSC1 0.8784 8.8369 -2.7895 29.1211
NCI-H3255 GDSC1 0.9626 9.8428 -3.2194 30.376
Lu-165 GDSC1 1.0746 8.8378 -2.6218 27.698
NCI-H1993 GDSC1 1.1214 11.944 -4.1347 32.5937
NCI-H2228 GDSC1 1.1649 7.4967 -1.8749 23.862
NCI-H196 GDSC1 1.3341 7.9164 -1.9424 23.5698
NCI-H2804 GDSC1 1.4102 7.7353 -1.7885 22.4769
NCI-H2291 GDSC1 1.4364 11.7145 -3.7563 30.4641
NCI-H1435 GDSC1 1.4402 9.3155 -2.5537 26.0664
A-549 GDSC1 1.4694 8.4211 -2.0824 23.7788
EMC-BAC-1 GDSC1 1.5387 9.2491 -2.4393 25.2128
NCI-H1650 GDSC1 1.6963 6.353 -0.8647 15.809
NCI-H1838 GDSC1 1.7377 10.3588 -2.8314 26.194
HCC15 GDSC1 1.7583 5.9941 -0.6368 14.0137
NCI-H2122 GDSC1 1.8014 8.2636 -1.7339 20.7802
NCI-H1915 GDSC1 2.1462 14.4147 -4.527 30.4746
SK-LU-1 GDSC1 2.4303 9.3955 -1.8073 19.1176
NCI-H2405 GDSC1 2.8609 12.2895 -2.9128 23.0388
NCI-H1755 GDSC1 2.8911 10.4832 -1.9999 18.7496
LOU-NH91 GDSC1 2.9425 12.8227 -3.1147 23.6153
NCI-H1092 GDSC1 3.4991 6.1963 0.4025 2.4645
RERF-LC-Sq1 GDSC1 4.3716 6.8257 0.545 0.9075
NCI-H2023 GDSC1 4.4118 14.5711 -2.9107 19.0011
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 -2.2206 1.2126 -2.509 45.4756
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
T.T GDSC1 -3.4842 -1.0942 -3.5094 59.9378
KYSE-450 GDSC1 -2.9951 -1.4033 -2.9986 54.3537
TE-4 GDSC1 -2.813 -1.1188 -2.8199 52.0912
KYSE-520 GDSC1 -2.5892 -0.1086 -2.6558 49.3557
KYSE-180 GDSC1 -2.5308 -1.3631 -2.5315 48.5883
OE21 GDSC1 -2.4831 -0.5264 -2.5066 48.0347
KYSE-140 GDSC1 -2.4573 1.8596 -2.9532 48.207
KYSE-150 GDSC1 -2.274 0.5786 -2.4235 45.7873
KYSE-270 GDSC1 -2.2395 2.4851 -2.9253 46.312
TE-9 GDSC1 -2.0576 -0.5024 -2.0689 42.729
EC-GI-10 GDSC1 -1.9864 0.9636 -2.1924 42.6038
KYSE-70 GDSC1 -1.8757 0.6401 -2.0044 41.0045
TE-10 GDSC1 -1.6762 0.4571 -1.7581 38.3547
OE33 GDSC1 -1.5139 3.7165 -2.6312 40.408
KYSE-410 GDSC1 -1.3603 2.7223 -2.068 37.4829
COLO 680N GDSC1 -1.0208 3.7103 -2.1162 35.5124
TE-8 GDSC1 -0.8081 6.7984 -3.3274 38.2454
TE-15 GDSC1 -0.3771 4.864 -1.9909 31.3453
TE-5 GDSC1 -0.2851 5.8112 -2.3528 32.4529
TE-1 GDSC1 -0.2565 4.9411 -1.9097 30.3369
OE19 GDSC1 0.2986 5.189 -1.5 25.4688
TE-11 GDSC1 2.5818 9.2992 -1.646 17.7666
KYSE-510 GDSC1 5.2346 16.2279 -3.1488 18.1271
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TOV-112D GDSC1 -3.8528 -1.6794 -3.863 64.461
OVCAR-3 GDSC1 -2.8328 2.1929 -3.4685 51.6612
A2780 GDSC1 -2.7476 -0.2511 -2.8074 51.2226
IGROV-1 GDSC1 -2.6681 3.215 -3.6536 50.1923
JHOS-2 GDSC1 -1.9797 2.5831 -2.6802 43.8326
OVCAR-8 GDSC1 -1.9719 3.3755 -2.9741 44.3413
Kuramochi GDSC1 -1.9254 3.1651 -2.8417 43.7577
OC 314 GDSC1 -1.6948 1.5483 -2.0279 39.7012
FU-OV-1 GDSC1 -1.662 4.5223 -3.1296 42.5478
JHOS-4 GDSC1 -1.6366 2.2427 -2.1888 39.8714
Caov-3 GDSC1 -1.5897 2.6964 -2.3034 39.927
OVISE GDSC1 -1.2693 1.6408 -1.5916 34.6707
ES-2 GDSC1 -1.2445 3.3925 -2.2141 37.2911
RMG-I GDSC1 -1.2355 4.1471 -2.5273 38.327
OVCAR-4 GDSC1 -1.0588 2.6392 -1.7144 33.9327
OVCAR-5 GDSC1 -0.8341 4.531 -2.2904 35.1139
EFO-21 GDSC1 -0.7982 3.2735 -1.6984 32.2643
TYK-nu GDSC1 -0.605 4.9153 -2.239 33.6416
OVK18 GDSC1 -0.5553 3.6427 -1.6086 30.4052
EFO-27 GDSC1 -0.5036 5.8178 -2.5658 34.3756
OVKATE GDSC1 -0.2793 6.2797 -2.5731 33.2866
OV-90 GDSC1 -0.2503 5.2942 -2.0718 31.0669
DOV13 GDSC1 -0.1867 6.5799 -2.6314 33.0603
TOV-21G GDSC1 -0.1418 6.3432 -2.4742 32.2437
OVTOKO GDSC1 0.1418 4.4021 -1.268 24.8371
OAW42 GDSC1 0.6041 3.9646 -0.6178 18.3571
SK-OV-3 GDSC1 1.33 7.9524 -1.9637 23.6947
OAW28 GDSC1 2.3867 9.7762 -2.0289 20.4162
Caov-4 GDSC1 3.1892 10.4627 -1.7747 16.7219
OV56 GDSC1 4.8794 14.6147 -2.6169 16.6708
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Panc 03.27 GDSC1 -3.3002 2.5389 -4.0915 55.2081
Panc 08.13 GDSC1 -3.263 1.6765 -3.7759 55.4874
MZ-PC-1 GDSC1 -3.1441 0.8384 -3.4241 55.0021
Capan-1 GDSC1 -2.3471 1.6582 -2.7717 47.0365
HuP-T4 GDSC1 -2.3462 -0.3346 -2.3777 46.3734
KP-4 GDSC1 -2.319 1.2933 -2.6377 46.5983
SUIT-2 GDSC1 -2.1383 1.4085 -2.4719 44.6717
BxPC-3 GDSC1 -2.0007 -0.2255 -2.0257 42.0856
DAN-G GDSC1 -1.3668 -0.4817 -1.3678 34.0428
Capan-2 GDSC1 -1.1928 5.8375 -3.2494 40.0581
QGP-1 GDSC1 -1.1785 3.0302 -1.9962 35.9928
YAPC GDSC1 -1.0953 4.3103 -2.4557 37.2406
HuP-T3 GDSC1 -0.9955 3.6909 -2.0816 35.2158
Panc 10.05 GDSC1 -0.9858 5.0717 -2.6896 37.3788
PSN1 GDSC1 -0.9485 5.0276 -2.6322 36.9844
PL4 GDSC1 -0.9282 4.7012 -2.4624 36.2898
KP-1N GDSC1 -0.7258 3.2705 -1.6218 31.4453
KP-3 GDSC1 -0.1639 6.4219 -2.5332 32.5799
SU.86.86 GDSC1 -0.1477 6.9994 -2.7993 33.4838
SW1990 GDSC1 0.0762 6.3756 -2.2865 30.4428
Panc 02.03 GDSC1 0.4545 5.3443 -1.4315 24.3612
HPAF-II GDSC1 0.6812 5.0867 -1.0977 21.3034
PaTu 8988t GDSC1 0.86 5.4638 -1.1245 20.7193
PaTu 8902 GDSC1 1.0537 8.3078 -2.3748 26.7125
AsPC-1 GDSC1 1.3081 9.6458 -2.8288 27.677
CFPAC-1 GDSC1 1.5385 10.5714 -3.1004 27.9106
MIA PaCa-2 GDSC1 2.0735 11.9121 -3.3366 27.0252
HPAC GDSC1 2.8548 11.8395 -2.695 22.1383
Panc 04.03 GDSC1 3.7645 15.3469 -3.7477 23.7592
Hs 766T GDSC1 3.8608 14.3316 -3.1812 21.4352
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1 -1.9501 -0.5899 -1.956 41.3609
MSTO-211H GDSC1 -1.6775 0.866 -1.8348 38.7403
NCI-H28 GDSC1 -1.3764 4.7016 -2.9161 40.3016
NCI-H2052 GDSC1 -1.3175 5.0883 -3.0301 40.2374
NCI-H2452 GDSC1 -1.1424 1.7939 -1.5016 33.3575
MPP 89 GDSC1 -0.9237 3.7502 -2.0333 34.5795
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 -2.532 0.7471 -2.7377 48.7813
22Rv1 GDSC1 -2.2525 1.6094 -2.6541 46.0252
VCaP GDSC1 -2.1387 -1.1549 -2.1391 43.6877
LNCaP clone FGC GDSC1 -2.0856 2.6313 -2.8118 44.9102
DU145 GDSC1 -1.9242 1.7331 -2.3334 42.532
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 -2.349 1.1016 -2.6208 46.8517
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CP50-MEL-B GDSC1 -3.8149 -1.6817 -3.8243 64.0557
Hs 938.T GDSC1 -3.5563 -1.3148 -3.5727 60.9046
A-431 GDSC1 -3.5405 -2.1128 -3.5412 61.1441
COLO 800 GDSC1 -3.3834 2.8154 -4.2772 55.6186
MZ-MEL-2 GDSC1 -3.2135 -1.4761 -3.2183 57.0225
Mel JuSo GDSC1 -3.1649 -0.3316 -3.2401 55.9392
COLO 679 GDSC1 -3.0539 -0.96 -3.0724 54.9696
DJM-1 GDSC1 -2.8768 -0.2779 -2.9411 52.7192
WM278 GDSC1 -2.6524 0.7301 -2.8649 50.0922
COLO 783 GDSC1 -2.6481 -0.659 -2.6696 50.0521
A101D GDSC1 -2.6145 -0.5377 -2.6424 49.6439
LB373-MEL-D GDSC1 -2.5671 -1.4699 -2.5675 49.0417
LB2518-MEL GDSC1 -2.5441 -0.5563 -2.568 48.7824
M14 GDSC1 -2.4707 0.7965 -2.6818 48.1111
UACC-257 GDSC1 -2.4628 -0.8833 -2.4699 47.7544
WM115 GDSC1 -2.4559 -0.0711 -2.5188 47.7659
SK-MEL-2 GDSC1 -2.4477 -1.263 -2.4486 47.5505
IGR-37 GDSC1 -2.3959 -1.6326 -2.396 46.9011
HT-144 GDSC1 -2.2594 0.5178 -2.3964 45.5893
CHL-1 GDSC1 -2.2591 -0.1812 -2.2996 45.3325
CP66-MEL GDSC1 -2.241 -0.3723 -2.2654 45.0585
SK-MEL-30 GDSC1 -2.2069 0.728 -2.3805 45.0665
IGR-1 GDSC1 -2.1941 3.1816 -3.1344 46.2182
SK-MEL-28 GDSC1 -2.193 1.8761 -2.6707 45.5379
RPMI-7951 GDSC1 -2.1733 1.521 -2.5419 45.1251
G-361 GDSC1 -2.1349 0.1935 -2.2108 43.9344
SH-4 GDSC1 -1.8299 1.9812 -2.3097 41.7203
MMAc-SF GDSC1 -1.7798 -0.2279 -1.7963 39.2944
SK-MEL-3 GDSC1 -1.7707 -0.1918 -1.789 39.1909
GAK GDSC1 -1.3352 1.4603 -1.6101 35.2089
Mel Ho GDSC1 -1.3328 1.3913 -1.588 35.0764
IPC-298 GDSC1 -1.0145 2.0939 -1.4643 32.3391
A-388 GDSC1 -1.0104 2.879 -1.7577 33.8423
SK-MEL-24 GDSC1 -0.6348 2.7281 -1.3002 29.1207
WM793 GDSC1 -0.4944 8.138 -3.6781 37.6333
SK-MEL-5 GDSC1 -0.2997 6.2914 -2.5981 33.4787
HMV-II GDSC1 -0.2151 4.5387 -1.6793 28.96
COLO 829 GDSC1 -0.0749 5.8787 -2.1858 30.7151
MZ-MEL-7 GDSC1 -0.0304 3.5731 -1.0471 24.2952
WM1552C GDSC1 0.0015 6.1466 -2.2442 30.6078
UACC-62 GDSC1 0.1183 3.7103 -0.9633 23.007
A-375 GDSC1 0.1716 7.1313 -2.5696 31.1799
SK-MEL-1 GDSC1 1.1179 9.6821 -3.007 29.0486
IST-MEL1 GDSC1 1.2573 9.1448 -2.6208 27.014
LOX-IMVI GDSC1 1.3865 7.6302 -1.7556 22.387
G-mel GDSC1 1.4656 10.1151 -2.9324 27.5254
451Lu GDSC1 1.6992 12.329 -3.847 29.8907
A2058 GDSC1 2.4954 11.5065 -2.8037 23.6627
WT2-iPS GDSC1 2.8867 16.8314 -5.1459 30.0438
MeWo GDSC1 3.7453 5.0768 0.9302 0.1456
RVH-421 GDSC1 4.0909 15.9741 -3.818 23.2015
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -1.9837 -0.2877 -2.0038 41.8514
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 633.T GDSC1 -4.5761 -1.9353 -4.5933 71.7872
GCT GDSC1 -3.6254 -0.0816 -3.7661 60.2821
TE 441.T GDSC1 -3.5484 -2.1201 -3.5491 61.2424
KYM-1 GDSC1 -3.5138 -2.439 -3.5139 60.8645
Rh41 GDSC1 -3.3795 -1.5562 -3.385 59.0292
EW-8 GDSC1 -3.3746 -0.5175 -3.4412 58.2911
G-402 GDSC1 -3.3543 -0.5472 -3.4168 58.1037
SK-UT-1 GDSC1 -2.9678 -0.4842 -3.016 53.8172
G-401 GDSC1 -2.9582 0.4766 -3.1446 53.3621
MES-SA GDSC1 -2.9375 -0.2309 -3.0108 53.3935
SW982 GDSC1 -2.8345 2.238 -3.4853 51.6667
Rh30 GDSC1 -2.7912 0.4382 -2.9564 51.6138
SK-LMS-1 GDSC1 -2.5852 -0.1252 -2.6496 49.3069
SW872 GDSC1 -2.4343 0.6971 -2.621 47.6803
VA-ES-BJ GDSC1 -1.8294 5.0743 -3.5437 44.2951
Rh18 GDSC1 -0.927 1.1633 -1.0857 29.5433
RD GDSC1 -0.1241 3.8258 -1.2569 26.0907
RKN GDSC1 0.1286 6.765 -2.4289 30.8043
MFH-ino GDSC1 0.7081 9.2223 -3.1292 31.0251
SW684 GDSC1 0.9214 8.6709 -2.6695 28.4784
HT-1080 GDSC1 1.1652 11.8224 -4.0369 32.1816
A-204 GDSC1 2.2058 12.0295 -3.29 26.4472
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-5 GDSC1 -4.1189 0.8549 -4.4899 62.8298
RF-48 GDSC1 -3.9331 -0.6614 -4.0161 63.8478
HGC-27 GDSC1 -3.6798 -0.8626 -3.7294 61.748
HSC-39 GDSC1 -3.6588 -1.332 -3.6772 62.0347
IM95 GDSC1 -3.4838 1.1039 -3.8591 57.7575
AGS GDSC1 -3.2555 -1.1704 -3.2701 57.408
Fu97 GDSC1 -2.9698 0.972 -3.2657 53.2793
MKN7 GDSC1 -2.832 1.4391 -3.2375 51.8186
SCH GDSC1 -2.8115 -0.7722 -2.8321 52.0399
SNU-16 GDSC1 -2.6348 -1.315 -2.6364 49.8877
OCUM-1 GDSC1 -2.5358 4.7459 -4.1305 49.2713
RERF-GC-1B GDSC1 -2.2294 1.4759 -2.5902 45.7098
MKN1 GDSC1 -1.4355 3.773 -2.5732 39.7294
NCI-N87 GDSC1 -1.4272 6.364 -3.726 42.285
GCIY GDSC1 -1.4178 2.8202 -2.1671 38.2552
23132/87 GDSC1 -1.3981 1.3018 -1.635 35.7665
KATO III GDSC1 -1.1486 4.3022 -2.5065 37.731
ECC10 GDSC1 -1.0666 5.4123 -2.9271 38.5382
NUGC-3 GDSC1 -0.6974 6.216 -2.9427 36.6204
SNU-1 GDSC1 -0.6404 2.8891 -1.3722 29.5748
NUGC-4 GDSC1 -0.4055 5.2244 -2.1888 32.377
MKN45 GDSC1 0.36 6.4804 -2.0771 28.2047
Hs 746.T GDSC1 0.5033 10.1158 -3.7533 33.7435
TGBC11TKB GDSC1 1.8558 13.7107 -4.4098 31.0119
MKN28 GDSC1 2.3041 8.2819 -1.3519 16.916
SNG-M GDSC1 -3.2148 -1.6515 -3.2171 57.0791
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1 -3.7258 -1.7513 -3.7321 63.1352
TT GDSC1 -3.4601 -1.991 -3.4611 60.1387
IHH-4 GDSC1 -2.9468 -0.384 -3.0037 53.5465
K5 GDSC1 -2.7414 -0.2525 -2.8006 51.1497
8505C GDSC1 -2.6787 1.0357 -2.964 50.361
ASH-3 GDSC1 -2.3235 -1.0498 -2.3255 46.0041
TT2609-C02 GDSC1 -1.866 2.5709 -2.5535 42.6734
8305C GDSC1 -1.798 1.8602 -2.2358 41.239
BHT-101 GDSC1 -1.6435 0.2096 -1.6903 37.7642
B-CPAP GDSC1 -1.1709 4.7104 -2.7114 38.5106
HTC-C3 GDSC1 -0.4214 3.6479 -1.4746 28.9349
ML-1 [Human leukemia] GDSC1 -0.3318 7.8764 -3.399 36.1886
CGTH-W-1 GDSC1 0.048 6.0561 -2.1566 29.9996
WRO GDSC1 0.2186 6.5763 -2.2535 29.6475
CAL-62 GDSC1 0.825 6.9652 -1.9024 25.3566
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-38 GDSC1 -4.6619 -1.4456 -4.7091 71.3201
SCC-9 GDSC1 -3.8379 -2.3286 -3.8386 64.7866
BICR 22 GDSC1 -3.6211 -2.0731 -3.6223 62.1038
LB771-HNC GDSC1 -3.4453 -1.5239 -3.4525 59.7844
CAL-27 GDSC1 -3.4258 -0.4273 -3.5055 58.7377
BB30-HNC GDSC1 -3.2576 -2.0183 -3.2579 57.6564
SCC-25 GDSC1 -3.2034 -1.5174 -3.2074 56.9121
NCI-H3118 GDSC1 -3.1902 -0.6128 -3.2379 56.3779
HO-1-N-1 GDSC1 -2.9854 -1.0437 -2.9983 54.1761
SKN-3 GDSC1 -2.9454 0.5278 -3.1408 53.2103
PCI-04B GDSC1 -2.9272 -0.6178 -2.9623 53.3858
PCI-15A GDSC1 -2.927 -0.9976 -2.9402 53.4639
SAS GDSC1 -2.9066 3.5352 -4.0307 51.9464
SAT [Human HNSCC] GDSC1 -2.8956 -0.8416 -2.9152 53.0598
OSC-19 GDSC1 -2.8492 -0.1851 -2.9225 52.3827
SCC-15 GDSC1 -2.7516 0.7419 -2.9752 51.1451
HO-1-u-1 GDSC1 -2.719 3.3051 -3.7423 50.5853
JHU-011 GDSC1 -2.5999 -0.8284 -2.6118 49.4586
DOK GDSC1 -2.5952 -0.9207 -2.6037 49.3982
OSC-20 GDSC1 -2.5849 3.29 -3.5932 49.5332
BICR 78 GDSC1 -2.5232 -0.2648 -2.5694 48.5528
PCI-06A GDSC1 -2.4123 0.647 -2.5868 47.4165
JHU-022 GDSC1 -2.3968 4.3335 -3.8122 48.2292
CAL-33 GDSC1 -2.3824 1.2554 -2.6968 47.2691
Ca9-22 GDSC1 -2.356 -0.1349 -2.4061 46.538
BICR 31 GDSC1 -2.022 2.4277 -2.6701 44.1403
PE/CA-PJ15 GDSC1 -2.0102 7.0819 -4.6368 46.4497
HSC-3 GDSC1 -1.8162 2.3693 -2.4273 41.9612
HSC-4 GDSC1 -1.6896 3.498 -2.725 41.8328
BICR 10 GDSC1 -1.4686 4.787 -3.0481 41.1776
KOSC-2 GDSC1 -1.4489 1.6989 -1.8051 36.9567
Detroit 562 GDSC1 -1.0938 4.8167 -2.6816 37.9702
HSC-2 GDSC1 -1.0186 3.9124 -2.2017 35.8435
BHY GDSC1 -1.014 3.552 -2.0411 35.1565
KON GDSC1 -0.91 4.2749 -2.2514 35.3971
PCI-30 GDSC1 -0.8539 5.3339 -2.6799 36.6173
FaDu GDSC1 0.1876 6.7092 -2.3473 30.195
BB49-HNC GDSC1 2.0291 11.7458 -3.2891 26.9934
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 GDSC1 -3.3708 -1.223 -3.3862 58.7611
RT-112 GDSC1 -3.2108 -0.7553 -3.2477 56.6862
BFTC-905 GDSC1 -2.6814 1.3302 -3.0431 50.375
647V GDSC1 -2.3377 -0.2128 -2.3792 46.2954
KU-19-19 GDSC1 -2.2416 -0.6939 -2.25 45.0074
639V GDSC1 -1.9819 1.5151 -2.3314 42.9938
CAL-29 GDSC1 -1.808 2.1159 -2.3307 41.6158
RT-4 GDSC1 -1.4463 0.7915 -1.5687 35.7412
SW1710 GDSC1 -1.2255 2.4797 -1.8318 35.567
T24 GDSC1 -1.078 5.3963 -2.931 38.6125
SW780 GDSC1 -0.9804 5.1759 -2.7322 37.4825
HT-1376 GDSC1 -0.7529 4.169 -2.0446 33.6355
5637 GDSC1 -0.7029 3.4406 -1.6713 31.5701
TCCSUP GDSC1 0.3582 5.0822 -1.3923 24.5668
J82 GDSC1 1.911 9.0537 -2.0406 22.0225
HT-1197 GDSC1 3.2838 10.3805 -1.668 15.8829
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEY GDSC1 -4.3046 1.9223 -4.985 62.3973
TC-YIK GDSC1 -4.0265 -2.2639 -4.0285 66.9189
NEC8 GDSC1 -3.76 -2.2408 -3.7608 63.8243
PA-1 GDSC1 -3.6849 -1.9573 -3.6875 62.8036
BPH-1 GDSC1 -3.6685 -0.5532 -3.7482 61.2627
KGN GDSC1 -3.2141 -1.5101 -3.2184 57.0397
NCC-IT GDSC1 -3.1999 -1.7156 -3.2015 56.9096
DoTc2 4510 GDSC1 -3.0338 -0.6663 -3.0699 54.6374
NT2-D1 GDSC1 -3.0275 -1.7438 -3.0281 54.7844
SW954 GDSC1 -2.9123 -1.5489 -2.9136 53.3447
C-33 A GDSC1 -2.828 -1.1763 -2.8337 52.2788
LB831-BLC GDSC1 -2.6922 -0.8506 -2.7054 50.5937
Ca Ski GDSC1 -2.3875 0.189 -2.4801 47.0023
HT-3 GDSC1 -2.2386 -0.2635 -2.271 45.0552
MS751 GDSC1 -2.1896 0.7766 -2.372 44.8888
C-4-I GDSC1 -2.1813 0.248 -2.268 44.5291
UWB1.289 GDSC1 -2.1365 1.2248 -2.4205 44.5363
JEG-3 GDSC1 -2.1097 -0.2013 -2.1413 43.4638
DSH1 GDSC1 -1.9232 0.0552 -1.9692 41.224
JAR GDSC1 -1.8957 0.897 -2.0786 41.4577
SiSo GDSC1 -1.7629 3.5319 -2.8161 42.5513
CAL-39 GDSC1 -1.6489 1.7779 -2.0475 39.4362
ACC-OV7 GDSC1 -1.6454 1.9596 -2.1021 39.6196
HeLa GDSC1 -1.4419 1.654 -1.7837 36.8078
SW962 GDSC1 -1.4152 1.05 -1.5906 35.649
SiHa GDSC1 -1.3545 1.7663 -1.7235 35.9154
OVCA433 GDSC1 -1.0154 5.1861 -2.7718 37.7999
ME-180 GDSC1 -0.8399 2.9389 -1.6023 32.0157
SW756 GDSC1 -0.4394 4.3455 -1.8106 30.8094
JHOS-3 GDSC1 -0.2572 6.6838 -2.7481 33.8168
OVMIU GDSC1 -0.1326 7.1073 -2.838 33.5494
PWR-1E GDSC1 0.0155 6.0771 -2.1973 30.3351
OMC-1 [Human cervical carcinoma] GDSC1 0.0215 6.9474 -2.6171 32.0395
SKN GDSC1 0.1082 7.5637 -2.8404 32.4773
HEC-1 GDSC1 0.191 5.5632 -1.7829 27.5138
SKG-IIIa GDSC1 0.2576 8.5953 -3.2153 33.1084
PEO1 GDSC1 2.0134 9.1839 -2.0244 21.5969
OV17R GDSC1 2.4449 12.4405 -3.3069 25.7851
OVCA420 GDSC1 2.9165 10.4132 -1.947 18.4024
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

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