Details of the Drug

General Information of Drug (ID: DMKWBJR)

• Drug Name: ISIS-PKK
• Synonyms: ISIS-PKKRx

Indication

Disease Entry	ICD 11	Status	REF
Amyloid cardiomyopathy	5D00.20	Phase 3	[1]

• Drug Type: Antisense drug
• Cross-matching ID: TTD ID: D0HL1X

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasma kallikrein messenger RNA (KLKB1 mRNA)	TTN0PCX	KLKB1_HUMAN	Not Available	[2]

References

• [1] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034193)
• [2] Clinical pipeline report, company report or official report of ISIS Pharmaceuticals.