Details of the Drug

General Information of Drug (ID: DMKWSFI)

Drug Name
CR-002
Synonyms CR-002 liquid API; Alpha 1 proteinase inhibitor (inhaled solution), CSL Behring; CR-002, CSL Behring
Indication
Disease Entry ICD 11 Status REF
Cystic fibrosis CA25 Phase 1 [1]
Cross-matching ID
DrugBank ID
DB05139
TTD ID
D0W0GE

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Platelet-derived growth factor B (PDGFB) TTQA6SX PDGFB_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01347190) Safety and Tolerability Study of Liquid Alpha1 Proteinase Inhibitor (API) in Subjects With Cystic Fibrosis. U.S. National Institutes of Health.
2 A phase I study of CR002, a fully-human monoclonal antibody against platelet-derived growth factor-D. Int J Clin Pharmacol Ther. 2008 May;46(5):236-44.