Details of the Drug

General Information of Drug (ID: DML0DBV)

Drug Name
ABT-737
Synonyms
ABT-737; 852808-04-9; ABT 737; ABT737; UNII-Z5NFR173NV; Z5NFR173NV; 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide; CHEMBL376408; C42H45ClN6O5S2; 4-{4-[(4'-Chlorobiphenyl-2-Yl)methyl]piperazin-1-Yl}-N-{[4-({(1r)-3-(Dimethylamino)-1-[(Phenylthio)methyl]propyl}amino)-3-Nitrophenyl]sulfonyl}benzamide
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 3 Molecular Weight (mw) 813.4
Logarithm of the Partition Coefficient (xlogp) 9
Rotatable Bond Count (rotbonds) 15
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C42H45ClN6O5S2
IUPAC Name
4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide
Canonical SMILES
CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
InChI
InChI=1S/C42H45ClN6O5S2/c1-46(2)23-22-35(30-55-37-9-4-3-5-10-37)44-40-21-20-38(28-41(40)49(51)52)56(53,54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-31/h3-21,28,35,44H,22-27,29-30H2,1-2H3,(H,45,50)/t35-/m1/s1
InChIKey
HPLNQCPCUACXLM-PGUFJCEWSA-N
Cross-matching ID
PubChem CID
11228183
CAS Number
852808-04-9
UNII
Z5NFR173NV
DrugBank ID
DB17023
TTD ID
D0L8WH
VARIDT ID
DR01411
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Apoptosis regulator Bcl-2 (BCL-2) TTJGNVC BCL2_HUMAN Inhibitor [1]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Protein Interaction/Cellular Processes [3]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Drug Response [3]
BAG family molecular chaperone regulator 3 (BAG3) OTVXYUDQ BAG3_HUMAN Drug Response [4]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [5]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [6]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Gene/Protein Processing [6]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Protein Interaction/Cellular Processes [7]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [8]
Homeobox protein NANOG (NANOG) OTUEY1FM NANOG_HUMAN Gene/Protein Processing [9]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Drug Response [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Apoptosis regulator Bcl-2 (BCL-2) DTT BCL2 2.52E-02 0.17 0.72
P-glycoprotein 1 (ABCB1) DTP P-GP 1.08E-01 -2.87E-01 -5.57E-01
P-glycoprotein 1 (ABCB1) DTP P-GP 2.05E-01 1.60E-01 1.37E+00
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 3.1751 7.7483 0.9853 15.0409
EW-3 GDSC2 -3.2227 2.3613 -3.5829 61.6472
EW-13 GDSC2 -2.129 6.1052 -3.5652 52.7314
CADO-ES1 GDSC2 -1.1942 6.538 -2.746 47.1506
HuO9 GDSC2 -0.7359 6.4381 -2.2235 44.0584
EW-12 GDSC2 -0.5573 2.3966 -0.6996 39.5162
EW-18 GDSC2 -0.1831 3.5346 -0.5634 36.8196
NOS-1 [Human HNSCC] GDSC2 -0.1808 4.3532 -0.8249 37.7484
EW-1 GDSC2 -0.1788 3.2943 -0.491 36.5103
TC-71 GDSC2 -0.0485 5.1942 -0.9953 37.5771
EW-22 GDSC2 -0.0365 3.8145 -0.4887 35.7162
EW-24 GDSC2 0.3476 5.9484 -0.8864 35.1846
EW-11 GDSC2 0.5011 5.7115 -0.6263 33.4884
ES5 GDSC2 1.1912 6.7085 -0.3618 29.2718
SK-ES-1 GDSC2; CTRP2 1.3307 5.5814 0.8693 27.3788
CHSA8926 GDSC2 1.6414 6.6982 0.0884 25.3241
ES4 GDSC2 1.7169 9.2198 -1.0521 29.9019
ES7 GDSC2 1.7448 5.1983 0.8804 20.677
CAL-78 GDSC2; CTRP2 1.9562 5.2318 1.6529 22.6898
EW-7 GDSC2 2.0423 4.6378 1.4316 16.2895
EW-16 GDSC2 2.3462 6.7521 0.7385 19.2071
TC71 CTRP2 2.4319 6.2474 1.8427 20.5851
U2OS GDSC2; CTRP2; CTRP1 2.6041 9.9488 0.4281 25.1849
A-673 GDSC2; CTRP2 2.687 5.304 2.4302 17.6736
U-CH2 GDSC2 3.147 4.7637 2.4505 6.0482
ES8 GDSC2 3.1645 6.2532 1.7231 10.5769
ES6 GDSC2 3.3297 9.7443 0.1172 19.3213
CAL-72 GDSC2 3.4822 7.3729 1.4284 11.4726
MG-63 GDSC2; CTRP2 3.7217 7.3172 2.7547 13.5743
ES1 GDSC2 3.7311 8.3943 1.1181 12.6483
SaOS-2 GDSC2; CTRP2 4.0576 7.4345 3.035 11.6143
HuO-3N1 GDSC2 4.1933 11.8188 -0.224 18.5405
SJSA-1 GDSC2 4.3645 10.5429 0.5392 14.2525
CHSA0108 GDSC2 4.4146 9.1237 1.2736 9.9934
NY GDSC2 4.4837 12.8998 -0.5366 19.2052
Hs 888.T CTRP2 4.8586 5.8513 4.5639 3.4699
H-EMC-SS GDSC2 4.9624 9.5308 1.4551 7.736
CHSA0011 GDSC2 5.1512 11.7431 0.5212 12.4825
SK-PN-DW GDSC2 5.2071 12.6174 0.1362 14.3114
SK-N-MC CTRP2 5.5085 9.2432 3.4361 6.8827
Hs 822.T CTRP2 6.3886 7.6739 4.7663 0.4864
SW1353 CTRP2 7.0724 8.5992 4.7044 0.3061
G-292 clone A141B1 GDSC2; CTRP2 7.3536 9.2355 4.5815 0.4478
HOS GDSC2; CTRP2 7.4043 11.4289 3.6824 3.2109
MHH-ES-1 GDSC2; CTRP2 11.5041 24.6301 0.1087 10.7802
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 205 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 3.9086 5.3173 3.7589 9.1773
JM1 GDSC2; CTRP2 -1.5143 0.451 -1.5152 44.7149
LC4-1 GDSC2 -6.9005 -4.3448 -6.9008 93.1314
MV4-11 GDSC2; CTRP2 -6.8234 -4.5612 -6.8234 79.6578
SK-MM-2 GDSC2 -6.8133 -4.8352 -6.8133 94.5516
EoL-1 GDSC2; CTRP2 -6.6341 -4.1391 -6.6342 78.3191
MHH-CALL-2 GDSC2 -6.5457 -4.4319 -6.5458 92.8076
KMS-27 CTRP2 -6.51 -4.3135 -6.51 77.6975
Mino CTRP2 -6.2586 -5.7563 -6.2586 76.2617
JVM-2 GDSC2; CTRP2 -6.2455 2.6885 -6.7046 68.3717
SUP-B15 GDSC2; CTRP2 -6.0516 -4.5505 -6.0516 74.8673
ALL-PO GDSC2 -5.7717 -2.3 -5.7816 84.0919
SUP-HD1 GDSC2; CTRP2 -5.7365 -1.3807 -5.7523 71.2669
KY821 GDSC2 -5.4433 -2.3342 -5.4491 82.927
ME1 GDSC2 -5.1721 -3.3996 -5.1722 84.0272
KO52 CTRP2 -5.1637 -2.2691 -5.1647 68.7336
RS4;11 GDSC2 -5.1232 -2.5677 -5.1249 81.9603
BALL-1 GDSC2 -5.0709 -3.6412 -5.0709 83.6648
NU-DHL-1 CTRP2 -4.9398 -1.8505 -4.9418 67.2139
Loucy GDSC2 -4.6762 -1.841 -4.6814 77.7371
NKM-1 GDSC2 -4.622 -0.9785 -4.6493 75.5465
Kasumi-2 CTRP2 -4.6133 -1.7729 -4.6146 65.174
ROS-50 GDSC2 -4.5017 -2.8717 -4.5017 78.1067
MOLM-13 GDSC2; CTRP2 -4.4649 -0.8582 -4.4739 63.9555
OCI-AML-2 GDSC2 -4.215 -1.411 -4.2219 73.8881
MY-M12 GDSC2 -4.1622 -2.4365 -4.1623 74.7766
OCI-Ly7 GDSC2 -4.0765 -2.4389 -4.0766 74.0091
KMS-12-BM GDSC2 -4.0315 -1.6768 -4.0337 72.9019
SU-DHL-16 GDSC2 -4.0257 -2.5465 -4.0257 73.5971
GDM-1 GDSC2; CTRP1 -3.885 -1.3893 -3.8858 75.9232
BV-173 GDSC2 -3.8762 -0.9102 -3.8891 70.6582
ML-2 GDSC2 -3.8721 -1.2172 -3.8783 71.0581
Karpas-231 GDSC2 -3.8636 -2.3086 -3.8637 71.9696
DoHH2 GDSC2; CTRP2 -3.6979 -2.4618 -3.6979 59.2334
SEM CTRP2 -3.6591 -1.2204 -3.6599 58.9496
KOPN-8 GDSC2 -3.4983 1.1993 -3.6674 64.8706
Kasumi-1 GDSC2 -3.4868 -0.4299 -3.5074 67.0557
MHH-CALL-4 GDSC2 -3.2363 -1.1984 -3.2378 65.5866
697 GDSC2; CTRP2 -3.1745 -0.9171 -3.1751 55.744
BONNA-12 GDSC2 -3.137 1.1316 -3.272 62.536
QIMR-WIL GDSC2 -3.0992 -0.4154 -3.1119 63.8446
MHH-CALL-3 CTRP2 -2.963 20.3445 -9.9137 51.4786
ATN-1 GDSC2 -2.9002 0.6134 -2.9643 61.2895
KG-1 GDSC2 -2.8106 0.4218 -2.8554 60.7147
Granta-519 GDSC2; CTRP2 -2.769 2.0338 -2.8798 52.865
ALL-SIL GDSC2; CTRP2 -2.7286 -0.8656 -2.7287 52.7865
VAL GDSC2 -2.6894 -0.9205 -2.6903 60.2695
KE-37 GDSC2; CTRP2 -2.4398 0.3816 -2.4464 50.8619
L-1236 GDSC2 -2.4029 0.3995 -2.4312 57.1397
MOLT-16 GDSC2; CTRP2 -2.3275 2.1535 -2.4263 50.1144
HDLM-2 GDSC2; CTRP2 -2.178 1.8986 -2.2459 49.1558
BE-13 GDSC2 -2.1298 -0.2251 -2.133 54.677
P12-Ichikawa GDSC2; CTRP2 -2.114 -0.318 -2.1142 48.7008
TALL-1 [Human adult T-ALL] GDSC2 -2.0527 -0.2641 -2.0549 53.9172
RL GDSC2; CTRP2 -2.0033 1.2958 -2.0277 47.9916
HEL 92.1.7 CTRP2 -1.8081 1.9645 -1.8648 46.7499
OCI-Ly3 CTRP2 -1.7159 2.1525 -1.7835 46.1641
DND-41 GDSC2 -1.7154 -0.3957 -1.7156 50.5494
VL51 GDSC2 -1.706 1.9474 -1.8603 50.4123
EM-2 GDSC2; CTRP2 -1.6465 0.6034 -1.649 45.5975
MOLT-4 GDSC2 -1.6168 2.1096 -1.7919 49.6052
TK [Human B-cell lymphoma] GDSC2 -1.5198 0.5147 -1.5296 48.5999
OCI-Ly19 GDSC2; CTRP2 -1.2926 0.7718 -1.2944 43.2435
SU-DHL-4 GDSC2; CTRP1 -1.288 1.5131 -1.3035 54.7245
P31/FUJ GDSC2; CTRP2 -1.2317 2.1621 -1.2787 42.9515
RC-K8 GDSC2 -1.1688 2.0732 -1.3031 45.3963
HAL-01 GDSC2 -1.0772 1.0338 -1.0967 44.2149
RPMI-8226 GDSC2; CTRP2; CTRP1 -0.7628 1.9189 -0.781 39.7711
Karpas-45 GDSC2 -0.7371 1.5613 -0.7795 40.9107
JVM-3 GDSC2; CTRP2 -0.7318 6.5709 -1.6914 41.5418
CCRF-CEM GDSC2 -0.7083 1.3487 -0.7333 40.5534
NALM-6 GDSC2; CTRP2 -0.5812 3.2715 -0.7057 38.8695
NU-DUL-1 GDSC2; CTRP1 -0.5604 1.0202 -0.5609 48.681
DB GDSC2; CTRP2 -0.3889 2.849 -0.4535 37.4297
PF-382 GDSC2; CTRP2 -0.3707 1.8141 -0.3779 37.1313
ARH-77 GDSC2 -0.3266 4.6595 -1.0912 39.4056
Peer CTRP2 -0.3145 2.1427 -0.3304 36.7854
WSU-NHL GDSC2 -0.2882 7.8566 -2.3737 41.9853
OCI-M1 GDSC2; CTRP2 -0.2351 2.3246 -0.2566 36.2757
SET-2 CTRP2 -0.2167 1.9359 -0.2244 36.109
MOLT-3 CTRP2 -0.1541 1.8362 -0.159 35.6835
P30/OHK GDSC2 -0.0613 1.9502 -0.1057 34.1697
MEG-01 GDSC2 0.1104 2.6173 -0.0187 32.8632
HC-1 GDSC2 0.1743 6.3135 -1.222 37.1159
TF-1 CTRP2 0.1817 2.1838 0.1744 33.4587
ST486 GDSC2; CTRP2 0.1904 2.5081 0.1725 33.4357
KMOE-2 GDSC2 0.2199 2.4462 0.1292 31.5829
HL-60 GDSC2; CTRP2 0.2508 3.0103 0.2032 33.1317
Reh GDSC2; CTRP2 0.3052 6.1436 -0.4242 34.8185
PL21 CTRP2; CTRP1 0.3314 3.6992 0.2093 32.8394
RCH-ACV GDSC2; CTRP2 0.3498 2.7249 0.3259 32.3957
Mono-Mac-6 GDSC2; CTRP2 0.3601 16.6287 -4.9148 41.7582
U-937 CTRP2; CTRP1 0.4256 3.6262 0.3203 32.1602
Hs 445 GDSC2 0.4278 8.3122 -1.8618 37.6345
SU-DHL-6 GDSC2; CTRP2 0.5061 3.0144 0.4696 31.3983
CESS GDSC2 0.6563 7.3381 -1.1855 34.7201
AML-193 CTRP2 0.6639 5.9431 0.0306 32.2701
NK-92MI GDSC2 0.6677 3.3935 0.4055 27.9862
HEL GDSC2; CTRP2 0.6687 2.6347 0.6576 30.2328
OCI-AML-5 CTRP2 0.6836 6.0438 0.0196 32.2373
H9 GDSC2 0.7874 3.0246 0.6311 26.2413
SUP-B8 GDSC2 0.8076 3.9483 0.3845 27.4331
L-428 GDSC2; CTRP2 0.8661 3.0004 0.8441 28.9565
M-07e CTRP2 0.9549 4.3073 0.7778 28.8898
OCI-Ly10 CTRP2; CTRP1 0.9854 4.9065 0.6786 29.1259
WSU-DLCL2 GDSC2; CTRP2; CTRP1 1.0624 5.1441 0.7013 28.8017
Karpas-1106P GDSC2 1.0685 4.4182 0.4956 25.6592
CMK CTRP2 1.1033 3.7201 1.0298 27.5529
KMS-21-BM CTRP2 1.2155 5.0813 0.885 27.6879
KMS-11 GDSC2; CTRP2; CTRP1 1.3098 5.9941 0.7162 27.967
CML-T1 GDSC2; CTRP2 1.3908 2.3843 1.3906 25.3944
MOLT-13 GDSC2; CTRP2 1.4233 17.2962 -4.2204 38.3349
Pfeiffer CTRP2 1.4321 3.526 1.3966 25.238
Ramos.2G6.4C10 GDSC2 1.4428 4.0692 1.0277 21.106
Ku812 GDSC2; CTRP2; CTRP1 1.6133 5.3478 1.2462 25.1871
Jiyoye GDSC2 1.6592 6.5323 0.1837 24.7776
P32/ISH GDSC2 1.6638 4.5705 1.0662 19.9493
MOLM-16 GDSC2; CTRP2; CTRP1 1.6846 4.4361 1.5429 23.9236
JURL-MK1 CTRP2 1.6859 3.5885 1.6568 23.5292
MOLP-2 CTRP2 1.7789 4.4666 1.6392 23.2902
IM-9 GDSC2 1.8962 8.741 -0.6514 27.68
MLMA GDSC2 1.9358 4.3111 1.4587 16.562
SUP-M2 GDSC2; CTRP2 2.0272 7.194 1.0476 24.6548
PL-21 GDSC2 2.0306 4.7444 1.373 16.6809
L-540 GDSC2 2.0368 6.2781 0.6722 20.7146
F-36P CTRP2 2.0437 5.7122 1.6052 22.5964
HuT 78 CTRP2 2.0889 5.5618 1.7016 22.1122
THP-1 GDSC2; CTRP2; CTRP1 2.095 4.0244 2.0458 20.8767
CTV-1 GDSC2 2.255 3.6257 2.0624 11.7472
RPMI-8402 GDSC2; CTRP2 2.2868 6.3872 1.6354 21.7705
EB1 CTRP2 2.2997 5.2087 2.0341 20.2762
BC-3 GDSC2 2.329 6.5915 0.8005 18.9168
EJM GDSC2; CTRP2; CTRP1 2.3299 5.8658 1.866 20.7966
SIG-M5 GDSC2; CTRP2 2.4629 9.4898 0.5002 25.3255
Karpas-422 GDSC2; CTRP2 2.5043 7.8925 1.256 22.556
JeKo-1 GDSC2; CTRP2 2.6545 6.6308 1.936 19.6026
HuNS1 CTRP2 2.6768 4.7337 2.5593 17.2448
SKM-1 GDSC2; CTRP2; CTRP1 2.7457 9.4982 0.7778 23.6185
Farage GDSC2 2.8219 4.1905 2.4234 7.332
EB2 GDSC2 2.8891 6.0844 1.5652 12.4276
BL-41 GDSC2 2.9979 7.4222 0.9959 15.5293
OPM-2 GDSC2; CTRP2 3.0262 5.59 2.713 15.6295
TUR GDSC2 3.14 6.5414 1.5581 11.68
A4/Fukuda GDSC2; CTRP2 3.1719 7.1437 2.2689 16.914
U-698-M GDSC2 3.3524 5.2152 2.4005 5.7459
SU-DHL-10 GDSC2 3.3751 7.0422 1.5059 11.303
Daudi GDSC2; CTRP2 3.3888 6.4832 2.7725 14.3783
DG-75 GDSC2 3.4315 8.0596 1.0438 13.9322
SU-DHL-5 GDSC2; CTRP1 3.6117 5.5045 3.3771 14.5368
MHH-PREB-1 GDSC2 3.6287 6.6501 1.9061 8.1036
SU-DHL-8 GDSC2; CTRP2 3.6516 5.9155 3.2752 11.7249
MN-60 GDSC2 3.6554 7.9889 1.2602 12.0097
BL-70 CTRP2; CTRP1 3.6834 5.3859 3.4927 10.8209
BC-1 GDSC2 3.785 6.4078 2.1459 6.2014
SCC-3 GDSC2 3.8398 6.4001 2.1902 5.7914
YT GDSC2 3.845 8.0311 1.3878 10.7294
OCI-AML-3 GDSC2; CTRP2; CTRP1 3.9073 5.6725 3.6396 9.623
Hs 611.T CTRP2 4.0153 9.6317 1.9384 16.137
WIL2 NS GDSC2 4.0941 8.1919 1.4967 9.4371
HH [Human lymphoma] GDSC2; CTRP2 4.1281 6.5695 3.5026 9.5595
GA-10 GDSC2; CTRP2 4.1719 5.1633 4.0894 7.1863
Toledo CTRP2 4.2287 11.1564 1.3837 17.8051
HD-MY-Z CTRP2 4.3358 8.5444 2.7677 12.0544
JSC-1 GDSC2 4.3589 10.6431 0.4855 14.5537
CTB-1 GDSC2 4.3637 6.5684 2.4629 3.0521
DEL GDSC2; CTRP2 4.4538 13.4771 0.4302 20.7268
KHM-1B CTRP2 4.4616 11.4752 1.4335 17.105
CA46 GDSC2; CTRP2 4.5028 6.7017 3.8156 7.3691
Namalwa GDSC2; CTRP2 4.5261 6.5364 3.9162 6.9039
A3/Kawakami GDSC2; CTRP2 4.658 5.2033 4.6093 3.837
LP-1 GDSC2; CTRP2; CTRP1 4.7041 10.2025 2.2802 13.2496
GR-ST GDSC2 4.7226 8.8306 1.6293 7.2204
KMS-20 CTRP2 4.9149 10.3511 2.3892 12.3701
MC116 GDSC2; CTRP2; CTRP1 5.0355 12.8707 1.2329 16.6579
CRO-AP2 GDSC2 5.1553 13.978 -0.5661 17.6928
NOMO-1 GDSC2; CTRP2; CTRP1 5.2038 14.4474 0.5858 18.6357
KE-97 CTRP2; CTRP1 5.2422 6.3563 4.6631 2.2302
Ki-JK CTRP2 5.3532 17.1331 -0.633 22.1966
EHEB CTRP2 5.3828 13.6591 1.1282 16.3549
AMO1 GDSC2; CTRP2; CTRP1 5.6315 7.1946 4.5429 2.0807
HT GDSC2; CTRP2; CTRP1 5.7116 8.7683 3.8292 4.8926
KMS-26 CTRP2 5.8055 8.3675 4.0954 3.6436
MOTN-1 CTRP2 5.9214 13.8876 1.4485 14.1496
K-562 GDSC2; CTRP2 6.0887 12.6824 2.1781 11.0233
P3HR-1 CTRP2; CTRP1 6.2209 9.3267 3.9206 3.7414
Jurkat GDSC2; CTRP2 6.3792 13.426 2.0306 11.1105
NCI-H929 GDSC2; CTRP2 6.5158 8.3817 4.5342 1.0984
KMM-1 CTRP2 6.5757 12.6741 2.5454 8.7543
Ci-1 CTRP2 6.7377 13.8143 2.1046 10.2368
JJN-3 GDSC2; CTRP2 7.0047 12.4563 2.9509 6.5058
U266B1 GDSC2; CTRP2 7.1486 10.4506 3.9741 2.4292
KCL-22 GDSC2; CTRP2 7.3038 15.7101 1.5856 11.3255
LAMA-84 GDSC2; CTRP2 7.3434 9.3086 4.5493 0.5235
MOLP-8 GDSC2; CTRP2 7.5319 9.3694 4.6042 0.3357
RPMI-6666 GDSC2; CTRP2 7.5519 15.7922 1.7202 10.454
SUP-T1 GDSC2; CTRP2 7.6429 9.8773 4.4591 0.5913
KM-H2 GDSC2; CTRP2 7.6593 13.3803 2.9405 5.6845
Karpas-299 GDSC2; CTRP2 8.4606 16.3876 2.0419 8.0262
SR GDSC2; CTRP2 8.5506 19.6779 0.5349 13.1517
SU-DHL-1 GDSC2; CTRP2 8.6657 16.0993 2.3045 6.823
Karpas-620 GDSC2; CTRP2 9.0478 20.3781 0.5362 12.4578
NB4 GDSC2; CTRP2 10.3645 21.5834 0.8158 9.9045
L-363 GDSC2; CTRP2 10.6723 23.0379 0.3323 11.0548
MM1.S GDSC2; CTRP2 11.2843 27.2451 -1.2501 14.8183
Raji GDSC2; CTRP2 11.5052 23.6449 0.5599 9.4346
⏷ Show the Full List of 205 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 4.8061 6.5786 4.1653 5.2254
T.T GDSC2 1.7045 4.0202 1.3267 18.2919
TE-6 GDSC2 2.2826 9.348 -0.5958 26.0512
TE-8 GDSC2 3.27 8.0667 0.9062 15.2144
KYSE-410 GDSC2; CTRP2; CTRP1 3.5305 6.4769 2.924 13.4072
TE-5 GDSC2; CTRP2 3.7628 7.3151 2.797 13.3017
OE21 GDSC2; CTRP2 4.0287 7.4573 2.9959 11.8428
KYSE-270 GDSC2 4.7146 6.9541 2.4931 2.3231
TE-11 GDSC2; CTRP2 4.9698 8.8154 3.203 8.8892
TE-4 GDSC2 5.0218 13.4546 -0.407 17.3027
EC-GI-10 GDSC2; CTRP2 5.4231 11.2275 2.3766 11.426
TE-10 GDSC2; CTRP2 5.8243 8.9905 2.959 2.8361
KYSE-510 GDSC2; CTRP2 6.1631 11.2612 2.9369 7.8317
KYSE-140 GDSC2; CTRP2; CTRP1 6.1752 11.0549 3.0473 7.3613
OE19 GDSC2; CTRP2 6.668 11.4568 3.2019 5.9857
KYSE-180 GDSC2; CTRP2 6.7662 14.0898 1.9904 10.6342
TE-9 GDSC2; CTRP2 6.7782 11.6135 3.2016 5.8306
KYSE-150 GDSC2; CTRP2 7.0691 8.3254 4.8022 0.1443
TE-14 CTRP2 7.3431 9.2018 4.5898 0.4344
COLO 680N GDSC2; CTRP2 7.4704 11.9244 3.4967 3.8193
KYSE-70 GDSC2; CTRP2 7.4964 9.3087 4.6124 0.3325
OE33 GDSC2; CTRP2 7.5639 9.5207 4.561 0.4068
KYSE-30 CTRP2 8.1398 13.4686 3.1908 4.2057
KYSE-520 GDSC2; CTRP2 8.43 17.7645 1.3705 10.4749
KYSE-450 GDSC2; CTRP2; CTRP1 8.5914 14.8478 2.8317 5.01
TE-1 GDSC2; CTRP2 9.8728 18.826 1.7831 7.2756
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.9941 8.6898 4.6372 0.4845
HPAF-II GDSC2; CTRP2 1.687 5.3765 1.3184 24.7053
PaTu 8988s CTRP2 2.1083 4.644 1.961 21.1275
Capan-2 GDSC2; CTRP2; CTRP1 2.3749 5.8432 1.9224 20.4572
PL4 GDSC2 2.5183 8.535 0.0187 22.4224
SU.86.86 GDSC2 3.3891 8.7578 0.6598 16.2604
Capan-1 GDSC2; CTRP2 3.5106 6.1286 3.0429 13.0039
KP-4 GDSC2 3.8954 5.725 2.5582 3.4008
KP-2 GDSC2; CTRP2 4.0297 6.619 3.3804 10.2976
AsPC-1 GDSC2; CTRP2 4.0396 7.6049 2.9373 12.0533
PaTu 8988t GDSC2 4.1204 13.4043 -1.0702 22.3769
Panc 03.27 GDSC2; CTRP2; CTRP1 4.1412 6.1701 3.6907 8.7826
Panc 10.05 GDSC2; CTRP2; CTRP1 4.2085 6.1026 3.7893 8.2181
Panc 04.03 GDSC2; CTRP2 4.9279 6.3475 4.3915 4.0157
MIA PaCa-2 GDSC2; CTRP2 4.9502 5.6103 4.7664 2.4272
DAN-G GDSC2; CTRP2 5.0199 9.5202 2.8941 10.0763
HuP-T4 GDSC2; CTRP2; CTRP1 5.1109 9.9162 2.7735 10.3961
MZ-PC-1 GDSC2 5.1419 8.0335 2.2542 2.9543
PaTu 8902 GDSC2; CTRP2; CTRP1 5.369 6.4227 4.7301 1.724
KP-1N GDSC2 5.4158 8.1151 2.3635 2.0595
QGP-1 GDSC2; CTRP2; CTRP1 5.6764 9.3788 3.5 6.3205
KP-3 GDSC2; CTRP2; CTRP1 5.6908 10.8816 2.7639 9.3484
SUIT-2 GDSC2; CTRP2; CTRP1 5.7199 8.1603 4.1348 3.6156
BxPC-3 GDSC2; CTRP2 5.8336 16.4391 0.1059 19.0132
PSN1 GDSC2; CTRP2 6.1155 14.6029 1.2448 14.5579
CFPAC-1 GDSC2; CTRP2; CTRP1 6.1493 9.2509 3.9082 3.8922
SW1990 GDSC2; CTRP2 6.2519 14.2711 1.5154 13.3091
SNU-213 CTRP2 6.5567 9.6466 3.9879 3.0367
HPAC GDSC2; CTRP2; CTRP1 6.6396 11.7252 3.0527 6.6242
HuP-T3 GDSC2; CTRP2 6.8377 10.2309 3.891 3.0696
Panc 05.04 CTRP2 7.0242 8.3668 4.7704 0.2034
TCC-Pan2 CTRP2 7.1668 12.0299 3.2598 5.0814
L3.3 CTRP2 7.3875 9.3989 4.5335 0.5393
YAPC GDSC2; CTRP2 7.42 8.8663 4.7418 0.1497
Panc 02.03 GDSC2; CTRP2 7.4898 13.143 2.9439 5.8847
Panc 08.13 GDSC2; CTRP2 7.4972 9.4168 4.5726 0.4088
Hs 766T GDSC2; CTRP2 7.8346 9.374 4.7156 0.1086
PK-45H CTRP2 7.9574 9.9527 4.5583 0.286
PK-59 CTRP2 8.1581 15.8955 2.0787 8.2812
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 75 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.6884 10.8925 3.4859 5.5765
COLO 792 GDSC2 0.2006 3.2459 -0.064 32.6143
WM278 GDSC2 0.2363 5.1535 -0.6768 34.995
COLO 783 GDSC2 0.6729 10.5306 -2.6732 38.3823
A101D GDSC2 1.1978 7.488 -0.7175 30.7044
CJM [Human melanoma] CTRP2 1.2141 4.5137 1.0175 27.2375
SK-MEL-1 GDSC2; CTRP2; CTRP1 1.4847 6.5976 0.6959 27.4939
SK-MEL-31 GDSC2; CTRP2 1.5555 9.1881 -0.2848 30.3632
A-388 GDSC2 1.7839 5.9533 0.5767 22.2156
Hs 940.T GDSC2; CTRP2 2.2202 3.6398 2.2076 19.9204
WM115 GDSC2; CTRP2 2.4209 4.9939 2.2223 19.2316
DJM-1 GDSC2 2.4923 8.5615 -0.0178 22.691
Hs 944.T CTRP2; CTRP1 2.73 5.8572 2.3025 18.0146
G-mel GDSC2 2.8816 4.6838 2.2464 8.2079
Hs 938.T GDSC2 2.9872 8.8774 0.2606 19.6477
451Lu GDSC2 3.1622 5.0199 2.3364 6.7204
CHL-1 GDSC2 3.1655 5.6564 2.0219 8.6951
VMRC-MELG GDSC2 3.172 11.5563 -0.9209 24.484
A-431 GDSC2 3.1829 9.3693 0.1816 19.4419
MZ-MEL-2 GDSC2 3.3143 8.8489 0.5521 17.0786
CP50-MEL-B GDSC2 3.3984 6.0069 2.0426 7.8781
GAK GDSC2 3.4495 6.0327 2.0713 7.553
Hs 852.T CTRP1 3.7401 6.4225 3.1662 25.3796
COLO 679 GDSC2 3.89 9.3927 0.746 14.3593
WM983B CTRP2 3.911 6.2709 3.4082 10.5004
LB2518-MEL GDSC2 3.9486 6.714 2.1155 5.995
HMV-II GDSC2 4.007 7.3595 1.8417 7.5442
WM1552C GDSC2 4.0243 8.1426 1.469 9.7782
WM35 GDSC2 4.0342 9.7285 0.6911 14.2786
WM266-4 CTRP2 4.0702 5.4259 3.9009 8.1773
RPMI-7951 GDSC2; CTRP2 4.1319 6.4487 3.5602 9.3212
SH-4 GDSC2 4.1564 8.2652 1.5065 9.2258
MeWo GDSC2; CTRP2 4.292 7.3197 3.3179 9.9001
IST-MEL1 GDSC2 4.4829 9.3233 1.2251 10.1159
WM88 CTRP2 4.6073 10.01 2.2906 13.412
SK-MEL-5 GDSC2; CTRP2; CTRP1 4.7585 13.4116 0.7268 19.0578
SK-MEL-24 GDSC2; CTRP2 4.865 10.181 2.4311 12.3008
MMAc-SF GDSC2 4.9412 11.9652 0.2642 14.2844
Malme-3M CTRP2 4.9597 21.5197 -3.1547 28.9855
UACC-62 GDSC2; CTRP2 5.06 6.3405 4.515 3.2152
Hs 895.T CTRP2 5.11 6.1893 4.6343 2.6118
CP66-MEL GDSC2 5.1395 13.7879 -0.4844 17.371
IGR-37 GDSC2; CTRP2 5.1923 7.1548 4.2225 4.1743
A2058 GDSC2 5.2214 13.805 -0.4332 16.9525
UACC-257 GDSC2; CTRP2 5.3532 11.0743 2.396 11.4796
LB373-MEL-D GDSC2 5.366 6.7987 2.8559 0.2786
Hs 936.T CTRP2; CTRP1 5.4005 6.8661 4.5344 2.4849
MZ-MEL-7 GDSC2 5.4146 7.3544 2.6697 0.7914
HT-144 GDSC2; CTRP2 5.4362 14.5219 0.7408 17.6392
A-375 GDSC2; CTRP2; CTRP1 5.492 6.7434 4.6633 1.801
COLO 741 CTRP2; CTRP1 5.5144 25.5005 -4.6831 30.6482
WT2-iPS GDSC2; CTRP2 5.5618 7.0501 4.5637 2.1012
M14 GDSC2 5.6398 18.5632 -2.4638 23.5262
Hs 688(A).T CTRP2 5.6682 7.6863 4.3294 2.897
SK-MEL-2 GDSC2; CTRP2 5.8976 7.1858 4.7188 1.0503
IGR-1 GDSC2; CTRP2 6.1768 11.1222 3.0154 7.4888
RVH-421 GDSC2; CTRP2 6.1855 11.6959 2.7394 8.6001
SK-MEL-3 GDSC2; CTRP2 6.193 9.9551 3.598 5.0842
G-361 GDSC2; CTRP2; CTRP1 6.2952 11.6873 2.8248 8.0751
Hs 839.T CTRP2 6.3052 10.6028 3.3624 5.8725
Hs 294T CTRP2 6.3491 9.836 3.7632 4.1913
SK-MEL-28 GDSC2; CTRP2; CTRP1 6.3541 7.2696 4.9075 0.1721
K029AX CTRP2 6.7594 9.511 4.1718 2.1209
SK-MEL-30 GDSC2; CTRP2 6.8152 7.9962 4.8235 0.1758
IPC-298 GDSC2; CTRP2 7.2469 11.4418 3.5831 3.7516
LOX-IMVI GDSC2; CTRP2 7.2609 12.3766 3.1573 5.3571
MDA-MB-435S CTRP2 7.6765 16.1662 1.6259 10.6192
IGR-39 CTRP2 8.3574 15.0686 2.5909 6.1446
Mel Ho GDSC2; CTRP2 9.0085 16.4311 2.3595 6.2332
Mel JuSo GDSC2; CTRP2 9.7161 20.3006 1.0074 10.0544
WM793 GDSC2; CTRP2 11.8335 24.8885 0.1889 10.1891
COLO 829 GDSC2; CTRP2 11.9537 27.8766 -1.1177 13.6899
WM1799 CTRP2 12.7039 25.027 0.6295 8.0379
COLO 800 GDSC2; CTRP2 13.5015 31.0431 -1.6251 13.3042
EquiPSC Line K2 GDSC2 5.3652 12.394 0.3552 12.8655
⏷ Show the Full List of 75 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC2 -0.0613 3.9102 -0.5463 36.0778
ESO-26 GDSC2 2.2974 5.5357 1.2773 16.2339
KYSE-50 GDSC2 2.6194 12.2214 -1.726 29.0904
KYAE-1 GDSC2 2.8165 4.3227 2.3563 7.7614
ESO-51 GDSC2 3.2916 6.3838 1.7657 9.9297
TE-12 GDSC2 3.3473 7.7261 1.141 13.6026
HCE-4 GDSC2 4.0272 7.6175 1.7298 8.1822
FLO-1 GDSC2 4.0448 12.8425 -0.8502 21.6952
KYSE-220 GDSC2 4.2076 8.5732 1.3928 9.7832
OACM5.1 C GDSC2 4.6433 8.4767 1.7452 6.7044
SK-GT-4 GDSC2 5.0449 14.059 -0.6871 18.4746
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 4.096 8.1407 1.5233 9.272
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-12 GDSC2 -6.8386 -3.6691 -6.8411 90.9266
CHP-126 GDSC2 -6.1656 -3.5781 -6.1663 89.1754
NH-12 GDSC2 -4.5222 2.2688 -4.9757 68.4279
SJNB-17 GDSC2 -4.4026 -2.431 -4.403 76.8058
KP-N-RT-BM-1 GDSC2 -3.7814 -0.7926 -3.796 69.7846
TGW GDSC2 -3.6875 -0.2517 -3.7225 68.3094
SK-N-SH GDSC2 -2.1648 1.8144 -2.3319 54.4461
IMR-32 CTRP2 -1.7184 2.4818 -1.8178 46.2233
SJNB-14 GDSC2 -1.6947 1.1655 -1.7488 50.328
NB(TU)1 GDSC2 -1.6445 2.8943 -1.9876 49.8655
SJNB-13 GDSC2 -1.4001 0.3015 -1.4036 47.3949
NH-6 CTRP2 -1.3787 2.1735 -1.4328 43.9347
SJNB-6 GDSC2 -1.0106 2.3124 -1.1738 43.9565
SiMa GDSC2 -0.703 5.6039 -1.8517 43.302
NB69 GDSC2 -0.6059 5.8171 -1.8333 42.7148
SK-N-BE(2) CTRP2 -0.4523 5.115 -0.9438 38.9524
LA-N-6 GDSC2 -0.4019 3.5268 -0.7998 38.9374
CHP-134 GDSC2 -0.2204 2.3605 -0.3302 36.0616
MHH-NB-11 GDSC2; CTRP2 0.2514 9.0884 -1.5959 37.7145
IMR-5 GDSC2 0.2845 3.2144 0.0358 31.7127
KP-N-YS GDSC2 0.7447 5.2547 -0.181 30.4709
SJNB-5 GDSC2 0.9681 8.0617 -1.2122 33.4433
CHP-212 GDSC2; CTRP2 2.0459 5.8145 1.5747 22.7003
SK-N-MC-IXC GDSC2 2.6496 4.0744 2.302 8.7216
SK-N-BE(2)-M17 GDSC2 2.7801 7.1548 0.9371 16.5769
KP-N-YN GDSC2; CTRP2 3.0451 9.6715 0.9915 22.0827
SK-N-DZ GDSC2; CTRP2 3.285 5.1776 3.1179 13.3802
SJNB-10 GDSC2 4.2267 6.9834 2.1793 4.9861
SK-N-FI GDSC2; CTRP2 4.3054 11.8989 1.0843 18.7503
SJNB-7 GDSC2 4.3552 9.9676 0.816 12.7599
SK-N-AS GDSC2; CTRP2 4.7653 5.3185 4.6911 3.2186
Kelly GDSC2; CTRP2 4.8964 13.6996 0.7008 18.8618
GOTO GDSC2 4.9101 11.9678 0.2405 14.4776
GI-ME-N GDSC2 5.9346 8.5333 2.4389 1.2363
NB1 GDSC2; CTRP2 9.1374 24.3171 -1.3018 17.7559
KP-N-SI9s CTRP2 10.0132 24.3868 -0.7316 15.0029
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-28 CTRP2 0.0252 6.2145 -0.7515 36.6765
SNU-245 CTRP2 2.7082 7.2799 1.7289 20.2355
SNU-869 CTRP2 4.3528 5.7753 4.0764 6.7134
HuCC-T1 GDSC2; CTRP2 5.4974 7.7918 4.1496 3.9219
SNU-308 CTRP2 5.5015 10.7601 2.6736 10.0638
SNU-1079 CTRP2 5.5371 15.7952 0.1871 19.3152
SNU-478 CTRP2 7.3531 10.495 4.0669 1.9167
SNU-1196 CTRP2 7.8962 9.4875 4.6986 0.1165
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1500 GDSC2; CTRP2 -4.5087 0.8693 -4.5994 63.1753
COLO 824 GDSC2 -2.8264 0.3522 -2.8671 60.9028
MDA-MB-330 GDSC2 -2.1674 3.5921 -2.7446 53.7578
HCC2157 GDSC2 -1.7219 2.2819 -1.9374 50.5401
HCC1569 GDSC2 -1.2636 1.6979 -1.3505 46.2114
MDA-MB-415 GDSC2; CTRP2 -0.8252 3.0037 -0.9311 40.4214
DU4475 GDSC2; CTRP2 0.2974 4.267 0.0736 33.388
HCC38 GDSC2; CTRP2 1.0915 4.9465 0.7844 28.4269
CAL-120 GDSC2; CTRP2 1.468 3.4401 1.4406 24.9722
HCC1428 GDSC2; CTRP2 1.651 6.4411 0.9315 26.1777
MDA-MB-157 GDSC2; CTRP2 1.8218 6.645 1.0407 25.2825
OCUB-M GDSC2 2.5208 5.3469 1.5833 13.572
MFM-223 GDSC2 2.7035 5.5345 1.6658 12.4249
EFM-192A GDSC2; CTRP2 2.9494 7.4531 1.9056 18.9104
Hs 578T GDSC2; CTRP2 3.0255 9.9553 0.8384 22.6783
EFM-19 GDSC2 3.1755 8.2117 0.754 16.3746
HCC1937 GDSC2; CTRP2 3.353 8.7733 1.7153 18.6
HDQ-P1 GDSC2; CTRP2 3.6695 10.6523 1.118 20.0829
MDA-MB-175-VII GDSC2 3.9184 8.1374 1.3914 10.5162
BT-483 GDSC2 4.0465 10.4433 0.3456 16.1067
Evsa-T GDSC2 4.0802 8.5129 1.3281 10.4841
HCC1599 GDSC2 4.0909 5.9843 2.564 2.9694
YMB-1-E GDSC2 4.0959 6.8932 2.1329 5.551
MRK-nu-1 GDSC2 4.1312 6.2114 2.4832 3.367
HCC1187 GDSC2 4.168 10.7935 0.2657 16.1983
MDA-MB-361 GDSC2; CTRP2 4.2067 8.1867 2.8203 12.1341
UACC-893 GDSC2 4.3231 13.313 -0.8658 21.0208
AU565 GDSC2; CTRP2 4.4001 7.8048 3.188 10.1799
HCC1419 GDSC2; CTRP2 4.4482 6.2067 3.99 6.8007
MDA-MB-436 GDSC2 4.4634 9.7725 0.9914 11.5068
HCC2218 GDSC2 4.4694 9.3076 1.2232 10.1587
UACC-812 GDSC2 4.5567 7.7579 2.0293 5.2068
HCC70 GDSC2 4.5936 11.2752 0.3489 14.6851
CAL-85-1 GDSC2; CTRP2 4.6646 6.9058 3.8733 6.7521
ZR-75-30 GDSC2; CTRP2 4.7105 6.5718 4.0781 5.8045
MDA-MB-453 GDSC2; CTRP2 4.9946 6.0777 4.5854 3.0639
CAL-51 GDSC2; CTRP2 5.3676 9.6137 3.1377 8.3877
HCC1143 GDSC2; CTRP2 5.5208 13.782 1.1798 15.8983
BT-20 GDSC2; CTRP2 5.6136 11.1464 2.5707 10.2807
Hs 578Bst CTRP2 5.6379 9.3275 3.4956 6.4053
MCF-7 GDSC2; CTRP2; CTRP1 5.7091 10.1722 3.1312 7.7968
HCC1806 GDSC2; CTRP2 5.8988 10.9466 2.8932 8.4522
HMC-1-8 CTRP2 6.2657 7.7394 4.6785 0.8392
KPL-1 CTRP2 6.3577 7.1276 4.96 0.0863
HCC202 CTRP2 6.5314 9.3483 4.1105 2.5999
CAMA-1 GDSC2; CTRP2 6.711 8.9659 4.3857 1.4211
ZR-75-1 CTRP2 6.7305 8.4805 4.6005 0.7316
SK-BR-3 CTRP2 7.1754 9.1999 4.5178 0.6856
JIMT-1 GDSC2; CTRP2 7.1919 8.4541 4.8023 0.1192
HCC1954 GDSC2; CTRP2 7.2037 19.048 -0.1263 17.3362
CAL-148 GDSC2; CTRP2 7.2333 20.1186 -0.6329 18.8095
MDA-MB-468 GDSC2; CTRP2 7.3991 11.5534 3.6231 3.4329
BT-474 GDSC2; CTRP2 7.4134 8.697 4.7979 0.0883
T-47D GDSC2; CTRP2 7.48 9.6867 4.4623 0.6623
BT-549 GDSC2; CTRP2 8.1947 17.8959 1.1487 11.581
MDA-MB-231 GDSC2; CTRP2 8.2189 16.2541 1.9487 8.679
HCC1395 GDSC2; CTRP2 8.926 17.4581 1.8358 8.1865
BT 239 CTRP2 -3.2698 0.5363 -3.2956 56.2142
BT 416 CTRP2 -1.0208 3.4101 -1.1965 41.8585
BT 428 CTRP2 1.4823 9.2478 -0.3862 30.8709
BT 245 CTRP2 1.5776 6.8908 0.6868 27.2413
BT 248 CTRP2 3.104 5.0307 2.958 14.5068
BT 286 CTRP2 3.2929 9.5336 1.298 20.3342
BT 340 CTRP2 3.4269 9.2819 1.5474 19.0607
BT 271 CTRP2 3.9519 14.653 -0.5973 25.0414
BT 216 CTRP2 4.0524 7.7634 2.8749 12.2754
BT147 CTRP2 4.1649 12.7504 0.5367 21.0016
BT 131 CTRP2 4.1889 9.792 2.0205 15.4156
BT 359 CTRP2 4.8989 8.5852 3.2563 8.8118
BT 172 CTRP2 5.055 9.2068 3.0807 9.229
BT 330 CTRP2 6.0173 14.9773 0.9813 15.6921
BT 232 CTRP2 6.1473 9.2987 3.8838 3.9934
BT 320 CTRP2 6.2939 12.9787 2.1874 10.6367
BT164 CTRP2 6.2967 9.135 4.062 3.0785
BT 333 CTRP2 6.4272 9.2555 4.0888 2.8082
BT 179 CTRP2 6.5353 14.3288 1.7021 12.1177
BT 422 CTRP2 6.5656 13.0265 2.3655 9.4858
BT 482 CTRP2 6.5775 16.82 0.5012 16.366
BT 145 CTRP2 6.5827 10.6522 3.5299 4.7969
BT 440 CTRP2 6.6016 10.4442 3.6415 4.3291
BT 504 CTRP2 6.6296 14.6343 1.6218 12.265
BT 444 CTRP2 7.0466 8.1999 4.8378 0.1038
BT 498 CTRP2 7.0495 8.6943 4.6592 0.4089
BT 224 CTRP2 7.2591 8.9592 4.6463 0.3516
BT 328 CTRP2 7.3185 15.4734 1.7112 10.8361
BT 139 CTRP2 7.5587 16.0877 1.582 10.9541
BT 112 CTRP2 8.1996 16.1021 2.008 8.4867
BT 187 CTRP2 9.3845 19.5218 1.1615 9.9501
BT 231 CTRP2 9.7771 22.5872 -0.0311 13.2674
BT 228 CTRP2 10.0683 26.388 -1.655 17.3973
BT 159 CTRP2 10.3642 22.5985 0.3435 11.3863
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.5131 7.6158 4.8433 0.2396
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-466 CTRP2 -5.3658 -0.6345 -5.3973 68.7319
PFSK-1 GDSC2 -0.3619 11.519 -4.1421 44.4093
D-247MG GDSC2 0.5504 5.3216 -0.4125 32.3959
KNS-81-FD GDSC2 0.7511 5.076 -0.1011 30.0775
D283 Med GDSC2; CTRP2 1.1229 2.285 1.1224 27.177
AM-38 GDSC2 1.6034 7.2631 -0.2157 26.9209
MOG-G-CCM GDSC2 2.6153 9.0494 -0.15 22.9082
KINGS-1 GDSC2 2.6808 6.8882 0.9799 16.6573
D-423MG GDSC2 2.7658 5.5802 1.7014 11.9923
SF126 GDSC2; CTRP2 2.847 5.583 2.5203 16.8674
KG-1-C CTRP2 2.8504 6.4016 2.2336 17.9287
GI-1 GDSC2 2.9399 6.9799 1.1655 14.7058
Hs 683 GDSC2; CTRP2 2.9563 4.591 2.8876 15.2171
SNU-626 CTRP2 3.163 7.5485 2.0836 17.6574
H4 GDSC2 3.165 6.3445 1.678 10.8575
D-392MG GDSC2 3.1757 7.052 1.3337 12.9522
D-502MG GDSC2 3.2161 7.3846 1.2017 13.6298
D-566MG GDSC2 3.4171 5.0213 2.5502 4.6167
Onda 11 GDSC2 3.566 7.5826 1.3914 11.4627
KS-1 [Human Krukenberg tumour] GDSC2 3.5945 6.6157 1.8963 8.2565
D-542MG GDSC2 3.6498 7.7405 1.3796 11.3032
D-263MG GDSC2 3.7941 7.225 1.7486 8.6508
ONS-76 GDSC2; CTRP2 3.8032 6.9345 3.0093 12.3535
Onda 10 GDSC2 3.8612 8.9983 0.9197 13.4512
GaMG GDSC2; CTRP2; CTRP1 3.8848 5.4993 3.6754 9.5544
U-118MG GDSC2; CTRP2 3.9067 10.1703 1.5743 17.8097
NMC-G1 GDSC2; CTRP2 4.0584 7.0961 3.1931 10.974
8-MG-BA GDSC2 4.0654 6.639 2.2347 4.9981
SF268 GDSC2; CTRP2 4.2181 7.5666 3.129 10.8464
MOG-G-UVW GDSC2 4.2838 9.9392 0.7767 13.1581
SK-MG-1 GDSC2 4.3632 12.2321 -0.2979 18.439
D-336MG GDSC2 4.3696 7.935 1.8194 6.846
LN-229 GDSC2; CTRP2; CTRP1 4.406 6.1676 3.9646 7.0103
SF539 GDSC2; CTRP2 4.4651 6.3036 3.9632 6.8652
Daoy GDSC2; CTRP2 4.5817 9.1735 2.6827 11.8623
KNS-42 GDSC2; CTRP2 4.703 6.8966 3.9139 6.4969
YH-13 GDSC2 4.7156 12.3463 -0.088 16.5614
M059J GDSC2 4.8643 10.1951 1.0704 10.1351
LN-405 GDSC2 5.0293 9.6794 1.4287 7.7517
SW1783 GDSC2; CTRP2 5.0585 12.9288 1.2233 16.6474
CAS-1 GDSC2; CTRP2 5.1163 6.4766 4.4966 3.1753
U-251MG GDSC2; CTRP2 5.1471 5.9996 4.7613 2.0042
GB-1 GDSC2; CTRP2 5.1615 6.4787 4.5344 2.926
SW1088 GDSC2; CTRP2 5.428 10.7744 2.607 10.4746
YKG-1 GDSC2; CTRP2 5.4898 6.5928 4.7352 1.51
SNU-738 CTRP2 5.4923 7.2944 4.3923 2.9207
SF295 GDSC2; CTRP2; CTRP1 5.5391 7.0194 4.5623 2.1421
LN-18 GDSC2; CTRP2 5.581 6.6985 3.8018 0.2198
D-245MG GDSC2 5.6705 9.2046 2.0303 3.3628
KALS-1 GDSC2; CTRP2 6.0579 13.5009 1.7479 12.763
SNU-489 CTRP2 6.9047 8.1224 4.8124 0.1691
42-MG-BA GDSC2; CTRP2 7.1637 9.1402 4.5361 0.6452
U-87MG ATCC GDSC2; CTRP2 7.1745 8.7583 4.6866 0.304
T98G GDSC2; CTRP2 7.2937 12.3106 3.2092 5.1155
A-172 GDSC2; CTRP2 7.3242 8.8723 4.7038 0.2273
DBTRG-05MG GDSC2; CTRP2 7.3878 9.6959 4.4173 0.8273
SNB-75 GDSC2; CTRP2 7.7112 15.4338 2.002 9.1738
SNU-1105 CTRP2 7.7564 19.3808 0.118 15.6821
Becker GDSC2; CTRP2 7.7721 13.5663 2.9247 5.6056
SNU-201 CTRP2 7.937 20.5416 -0.3194 16.755
DK-MG GDSC2; CTRP2 8.9529 16.1159 2.4699 5.9044
CCF-STTG1 CTRP2 10.9852 23.3832 0.3661 10.5916
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC2 0.2247 4.038 -0.2777 33.4538
TGBC24TKB GDSC2 0.2995 2.7356 0.163 31.0149
ETK-1 GDSC2 3.8568 7.7673 1.5277 9.848
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-108 CTRP2; CTRP1 0.297 3.5559 0.1927 33.0098
KLE GDSC2; CTRP2; CTRP1 1.2606 5.4642 0.8278 27.7411
MFE-280 GDSC2 1.5735 5.907 0.3879 24.0708
HEC-151 CTRP2; CTRP1 1.5807 4.6647 1.3836 24.8067
HEC-1-A CTRP2 2.5529 4.3943 2.4853 17.8955
JHUEM-3 CTRP2 3.0873 7.3896 2.0754 17.8888
JHUEM-1 CTRP2 3.2571 8.2704 1.8535 18.3076
EFE-184 CTRP2 3.595 4.7325 3.5511 10.8852
HEC-265 CTRP2; CTRP1 4.0266 8.6864 2.4081 14.2294
HEC-6 CTRP2; CTRP1 5.2818 8.9831 3.3826 7.5254
HEC-59 CTRP2; CTRP1 5.3692 6.3515 4.7655 1.5769
HEC-50B CTRP2 5.4046 11.238 2.3562 11.5438
MFE-319 GDSC2; CTRP2; CTRP1 5.431 9.9049 3.0437 8.6612
ESS-1 GDSC2; CTRP2 5.7953 10.1997 3.1841 7.4282
JHUEM-2 CTRP2; CTRP1 5.881 11.6101 2.5501 9.8871
HEC-251 CTRP2; CTRP1 6.0323 11.6696 2.6369 9.2733
MFE-296 GDSC2; CTRP2 6.5247 10.7214 3.4576 5.1666
HEC-1-B CTRP2 7.2244 8.8752 4.6634 0.3307
JHUEM-7 CTRP2 8.3304 18.6895 0.8597 12.3822
EN GDSC2; CTRP2 9.0207 17.878 1.6997 8.5499
RL95-2 GDSC2; CTRP2 9.2087 17.6165 1.9373 7.4925
AN3-CA GDSC2; CTRP2 10.8741 22.089 0.8929 9.087
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 5.1908 7.313 4.1421 4.5145
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 -3.141 2.9554 -3.402 54.8314
A-704 GDSC2 -0.2982 6.028 -1.5948 40.535
KTCTL-13 GDSC2 0.6367 4.3054 0.0743 29.7921
LB996-RCC GDSC2 0.8769 3.7403 0.5286 26.3594
TUHR4TKB CTRP2 1.1588 4.2819 1.0031 27.4643
BB65-RCC GDSC2 1.2757 4.7236 0.5952 24.2152
KTCTL-1M GDSC2 1.5992 5.0052 0.8152 21.6378
KTCTL-195 GDSC2 1.8023 5.0559 1.0021 19.7511
A-498 GDSC2; CTRP2 1.8662 3.9951 1.8066 22.4338
HA7-RCC GDSC2 2.0982 4.3373 1.618 14.9691
NCC010 GDSC2 2.2056 8.1211 -0.0614 23.9131
KTCTL-26A GDSC2 2.2753 4.7322 1.6278 14.2119
RCC10RGB GDSC2; CTRP2; CTRP1 2.7845 4.8969 2.6414 16.6192
VMRC-RCW GDSC2; CTRP2; CTRP1 2.8134 5.6556 2.4604 17.1865
UO-31 GDSC2; CTRP2 3.0249 4.5376 2.9696 14.7148
VMRC-RCZ GDSC2; CTRP2 3.2255 7.0483 2.3654 16.3963
KTCTL-140 GDSC2 3.2874 6.7801 1.564 11.2002
SW156 GDSC2 3.3788 5.7206 2.1697 7.1309
RXF 393L GDSC2 3.4849 10.3536 -0.059 19.732
KMRC-2 CTRP2 3.4882 6.3626 2.9263 13.5132
NCC021 GDSC2 3.7613 13.0572 -1.1845 23.7976
LB1047-RCC GDSC2 3.8998 7.7655 1.5614 9.5316
LB2241-RCC GDSC2 4.1394 7.7548 1.7443 7.8247
SW13 GDSC2 4.1685 9.3186 0.9966 12.2052
TK-10 GDSC2 4.1766 9.5021 0.912 12.6685
786-O GDSC2; CTRP2 4.3646 8.169 2.9776 11.1266
Caki-1 GDSC2; CTRP2 4.399 7.5929 3.2895 9.7654
769-P GDSC2; CTRP2 4.4397 9.1623 2.5598 12.676
CAL-54 GDSC2; CTRP2 4.4984 5.4101 4.3707 5.1855
KTCTL-21 GDSC2 4.6978 12.5451 -0.1993 17.1329
BFTC-909 GDSC2; CTRP2 4.8238 5.4468 4.7063 2.9955
SN12C GDSC2 4.8712 11.9406 0.2256 14.6446
KMRC-3 CTRP2 6.4137 11.0167 3.2379 6.2141
ACHN GDSC2; CTRP2 6.594 12.0679 2.8544 7.4886
KMRC-1 GDSC2; CTRP2 7.632 14.3519 2.4653 7.5298
SNU-1272 CTRP2 7.8217 19.0901 0.3074 14.973
OS-RC-2 GDSC2; CTRP2 8.3289 16.7402 1.7905 9.1096
Caki-2 CTRP2 9.25 66.2005 -21.9877 39.1044
KMRC-20 GDSC2; CTRP2 9.9559 19.2763 1.6275 7.708
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-175 GDSC2; CTRP2; CTRP1 -1.8266 11.6874 -4.8584 48.2509
GP2d CTRP2; CTRP1 -1.43 2.8637 -1.5566 44.4041
SW48 GDSC2; CTRP2; CTRP1 0.1473 3.4067 0.0526 33.9708
COLO 320HSR GDSC2 0.5589 4.9961 -0.2722 31.7585
SK-CO-1 GDSC2; CTRP2; CTRP1 0.6081 3.4034 0.5415 30.8205
SNU-81 GDSC2; CTRP2; CTRP1 0.7647 5.9119 0.1502 31.5655
HCC2998 GDSC2 1.0364 6.2584 -0.3132 29.7322
SW626 GDSC2 1.1244 3.4865 0.8768 23.3587
SW480 CTRP1 1.3638 3.741 1.3036 54.5583
DiFi GDSC2 1.4544 4.4814 0.8816 21.873
SW837 GDSC2 1.7907 4.9294 1.0457 19.5472
COLO205 GDSC2; CTRP2; CTRP1 2.0807 3.5137 2.0701 20.8415
COLO 678 GDSC2; CTRP2; CTRP1 2.3314 5.1192 2.0927 19.969
SW1116 GDSC2 2.3881 4.8692 1.6784 13.4789
CaR-1 GDSC2 2.471 4.9582 1.7191 12.9238
SNU-503 CTRP2 2.5267 7.4938 1.4495 21.7809
CL-11 GDSC2; CTRP2 2.5442 5.0892 2.3328 18.4586
SW620 GDSC2; CTRP2; CTRP1 2.5751 5.5876 2.223 18.7628
GP5d GDSC2 2.6168 6.2322 1.2442 15.3004
RCM-1 [Human ESC] GDSC2; CTRP2; CTRP1 2.7527 4.1229 2.7289 16.4172
LS513 CTRP2; CTRP1 2.7607 5.5363 2.4411 17.4133
C2BBe1 GDSC2; CTRP2; CTRP1 2.7826 5.8894 2.3484 17.6916
LS123 GDSC2; CTRP2; CTRP1 2.9814 5.6116 2.6573 15.9664
MDST8 GDSC2; CTRP1 3.1554 8.0621 1.8463 23.418
SW948 GDSC2; CTRP2; CTRP1 3.2305 5.629 2.9222 14.2573
HT115 GDSC2; CTRP2; CTRP1 3.535 7.7173 2.3849 15.5165
NCI-H747 GDSC2; CTRP2 3.6341 5.5032 3.4019 11.3003
DLD-1 CTRP2; CTRP1 3.6806 4.7699 3.6371 10.3145
SNU-C2A CTRP2; CTRP1 3.686 8.9306 1.9651 16.8073
SNU-C5 GDSC2; CTRP2; CTRP1 3.7155 5.5744 3.4666 10.8232
LS1034 GDSC2 3.7619 11.1813 -0.2474 19.8318
CL-40 CTRP1 3.8633 7.5358 2.7959 27.2546
SNU-C1 GDSC2; CTRP2 3.9043 12.5422 0.4057 22.0361
SW1417 GDSC2; CTRP2 4.0225 8.4803 2.5036 13.8529
CL-34 CTRP1 4.1872 7.3974 3.1793 22.6747
SNU-283 GDSC2 4.1877 7.236 2.031 5.9672
SNU-1040 CTRP1 4.2996 6.8352 3.5534 19.0906
KM12 GDSC2; CTRP2; CTRP1 4.5256 7.1329 3.6317 8.0665
HCT 8 CTRP2; CTRP1 4.6167 7.1927 3.6889 7.6217
CW-2 GDSC2; CTRP2; CTRP1 4.632 8.5853 3.019 10.3631
SW1463 GDSC2 4.6598 10.0248 1.0094 10.9414
COLO 320 CTRP2; CTRP1 4.9261 7.6414 3.7499 6.6925
NCI-H508 GDSC2; CTRP2; CTRP1 5.1405 9.8993 2.8068 10.1998
LS411N GDSC2; CTRP2; CTRP1 5.1638 7.3462 4.1028 4.7317
LS180 GDSC2; CTRP2; CTRP1 5.2055 9.035 3.2934 8.0448
HCT 116 GDSC2; CTRP2; CTRP1 5.2075 8.3506 3.6373 6.5998
SNU-C4 CTRP2; CTRP1 5.2674 6.6056 4.559 2.6195
SW403 CTRP1 5.3182 6.7096 4.548 5.5265
SNU-407 GDSC2; CTRP2 5.3438 10.4059 2.7223 10.1583
LoVo GDSC2; CTRP2; CTRP1 5.5017 9.1754 3.4644 6.7764
HT-55 GDSC2; CTRP2; CTRP1 5.5554 8.8803 3.6538 5.8901
HT-29 GDSC2; CTRP2; CTRP1 5.6909 7.3047 4.5308 2.0425
HCC-56 CTRP2 5.6957 9.006 3.6996 5.4571
SNU-C2B GDSC2 5.6969 14.0836 -0.2312 14.9762
SNU-61 GDSC2; CTRP2; CTRP1 6.1116 9.5242 3.7499 4.5886
T84 GDSC2; CTRP2 6.4449 11.3231 3.111 6.6804
RKO GDSC2; CTRP2; CTRP1 6.5825 9.9913 3.8431 3.5641
OUMS-23 CTRP2 6.7736 7.8575 4.8573 0.1349
NCI-H716 GDSC2; CTRP2 7.2589 12.9827 2.8695 6.4756
CCK-81 GDSC2; CTRP2 7.3255 15.8304 1.5425 11.4514
SNU-1033 CTRP2 7.5101 9.9482 4.3726 0.8742
HCT 15 GDSC2; CTRP2 9.5204 17.8164 2.0332 6.8076
COLO201 CTRP2 12.4678 25.8978 0.1053 9.7743
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 0.0675 2.6386 -0.0692 33.3263
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-2 GDSC2; CTRP2 -1.5362 1.9522 -1.5809 44.9509
Li-7 CTRP2 -1.3371 3.2003 -1.5037 43.8763
SNU-878 CTRP2 -0.3874 3.6295 -0.551 37.7054
Huh-7 GDSC2 1.8131 3.7296 1.5483 16.5698
SNU-182 CTRP2 1.8382 4.1727 1.7527 22.7085
JHH-5 CTRP2 2.091 4.8802 1.8901 21.4313
HuH-6 CTRP2 2.3005 5.0547 2.0757 20.1248
SNU-387 GDSC2; CTRP2 3.1073 8.2185 1.7269 19.1808
HuH-1 GDSC2 3.1977 6.5123 1.622 11.1072
SNU-398 GDSC2; CTRP2; CTRP1 3.3629 9.5167 1.3738 19.8765
HLE GDSC2 3.586 9.2901 0.5549 16.2648
SNU-423 GDSC2; CTRP2 3.8228 8.5225 2.2917 15.18
PLC/PRF/5 CTRP2 4.4515 7.7216 3.2768 9.6971
JHH-7 GDSC2 4.648 10.3038 0.8649 11.7794
SNU-449 GDSC2; CTRP2; CTRP1 5.0138 9.4493 2.9243 9.9628
Hep-G2/C3A GDSC2 5.0838 6.3224 2.9189 0.2432
JHH-1 GDSC2; CTRP2 5.2012 13.8425 0.886 17.589
HLF CTRP2 6.1492 10.6762 3.2142 6.7198
Hep-G2 CTRP2; CTRP1 6.6991 8.3619 4.6338 0.658
Hep 3B2.1-7 GDSC2; CTRP2 7.2783 8.6076 4.7803 0.1295
JHH-6 GDSC2; CTRP2; CTRP1 8.4023 16.6298 1.8905 8.6508
SNU-475 CTRP2 8.8984 17.1475 1.963 7.7689
JHH-4 GDSC2; CTRP2 9.809 17.2399 2.4569 5.0703
SK-HEP-1 GDSC2; CTRP2 10.669 22.7161 0.4796 10.6061
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 221 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1963 GDSC2; CTRP1 -5.3137 -1.5678 -5.3208 83.3852
NCI-H146 GDSC2; CTRP2 -3.8116 -0.9572 -3.8141 59.9141
NCI-H1341 GDSC2; CTRP2 -3.7671 -0.506 -3.7741 59.5521
COR-L303 GDSC2 -3.5425 -1.9984 -3.5426 68.8008
NCI-H209 GDSC2 -3.4411 -0.8894 -3.448 67.1853
NCI-H1105 GDSC2; CTRP2; CTRP1 -3.2506 -0.0031 -3.2602 56.1768
NCI-H748 GDSC2 -3.2191 -0.1096 -3.2466 64.568
COR-L32 GDSC2 -3.1548 -1.3313 -3.1555 64.8744
DMS 53 GDSC2; CTRP2 -2.9056 -0.5628 -2.9067 53.9576
COR-L311 GDSC2 -2.6576 -0.0176 -2.6741 59.659
COR-L95 CTRP2 -2.6396 1.0445 -2.6703 52.1461
NCI-H1836 GDSC2; CTRP1 -2.3654 -1.2916 -2.3654 63.9082
COLO 699 CTRP2; CTRP1 -2.2695 4.1823 -2.6967 49.7724
NCI-H720 GDSC2 -2.1413 -0.5976 -2.1419 54.8158
NCI-H524 GDSC2 -2.0379 1.0141 -2.0953 53.5799
NCI-H211 GDSC2; CTRP2 -1.7155 1.2453 -1.7312 46.0809
Lu-135 GDSC2 -1.7021 0.7795 -1.7282 50.4061
NCI-H2106 CTRP2 -1.6444 1.5618 -1.6708 45.6303
Lu-134-A GDSC2 -1.5219 1.1238 -1.5643 48.652
NCI-H64 GDSC2 -1.3409 1.6165 -1.4226 46.9478
NCI-H1930 CTRP1 -1.0816 0.6617 -1.0822 85.9856
NCI-H250 GDSC2 -1.055 1.1548 -1.0806 44.013
NCI-H1436 GDSC2 -1.0338 1.2987 -1.0683 43.8309
NCI-H1048 GDSC2; CTRP1 -0.9214 4.492 -1.2999 51.4398
IST-SL2 GDSC2 -0.8867 2.4306 -1.062 42.8082
COR-L88 GDSC2; CTRP2; CTRP1 -0.8443 1.429 -0.8503 40.2758
Ms-1 GDSC2 -0.8018 3.265 -1.163 42.5076
NCI-H510A GDSC2 -0.7927 0.7159 -0.7962 41.307
NCI-H2196 GDSC2; CTRP2 -0.691 5.3025 -1.2556 40.5863
COR-L279 GDSC2; CTRP1 -0.6871 2.0629 -0.7094 49.7532
NCI-H1770 GDSC2 -0.6049 2.8351 -0.8411 40.3075
NCI-H69 GDSC2; CTRP2 -0.5943 2.8986 -0.6747 38.8336
T3M-10 CTRP2; CTRP1 -0.5843 2.2363 -0.6122 38.6149
NCI-H847 GDSC2 -0.583 2.2984 -0.7101 39.7104
NCI-H1155 GDSC2; CTRP2 -0.5396 2.443 -0.5784 38.3512
NCI-H2171 GDSC2; CTRP2 -0.4645 1.5496 -0.4682 37.7435
DMS 79 GDSC2; CTRP2 -0.2968 2.2125 -0.315 36.6752
NCI-H2141 GDSC2; CTRP2; CTRP1 -0.0745 4.1615 -0.3084 35.8581
NCI-H345 GDSC2 -0.0626 2.5395 -0.1912 34.581
DMS 454 CTRP2 0.0928 3.019 0.0369 34.208
IST-SL1 GDSC2 0.1154 2.2304 0.0489 32.5083
NCI-H835 GDSC2 0.2381 2.8196 0.0791 31.7373
HCC4006 CTRP2; CTRP1 0.2442 3.3668 0.1604 33.2936
NCI-H2029 GDSC2; CTRP2; CTRP1 0.4114 5.0656 0.0118 33.1866
SCLC-21H CTRP1 0.4123 3.5904 0.3109 65.1913
COR-L321 GDSC2 0.4835 3.0281 0.2992 29.4206
NCI-H1694 GDSC2; CTRP2; CTRP1 0.5275 4.8427 0.1952 32.2196
HOP-92 GDSC2; CTRP2 0.5643 3.7694 0.4482 31.276
HCC1833 CTRP2; CTRP1 0.6363 6.8603 -0.3128 33.3674
NCI-H1435 GDSC2; CTRP1 0.8018 3.1031 0.7712 37.3102
NCI-H1648 GDSC2 0.9053 3.5174 0.6288 25.6982
CPC-N GDSC2 0.9081 2.4976 0.8584 24.4761
HCC15 GDSC2; CTRP2; CTRP1 0.933 4.3375 0.7483 29.0605
NCI-H1092 GDSC2; CTRP2 0.9714 4.6837 0.7166 29.0432
LOU-NH91 GDSC2; CTRP2 1.0238 4.2174 0.8691 28.3569
COLO 668 GDSC2; CTRP2; CTRP1 1.0362 4.211 0.8836 28.2675
LB647-SCLC GDSC2 1.0629 7.6511 -0.9265 32.0587
NCI-H1876 GDSC2; CTRP1 1.0818 8.0606 -0.3005 39.0296
NCI-H3255 GDSC2; CTRP1 1.1269 4.8206 0.8539 35.5042
NCI-H1993 GDSC2 1.2493 4.3122 0.7293 23.6014
NCI-H2170 GDSC2; CTRP2 1.2761 5.7284 0.7647 27.9079
UMC-11 GDSC2 1.2772 4.2377 0.7873 23.1615
NCI-H526 GDSC2; CTRP2 1.4105 12.1235 -1.7639 34.4229
NCI-H2066 GDSC2 1.4373 4.2398 0.9578 21.5206
NCI-H2342 GDSC2; CTRP2; CTRP1 1.4525 6.1741 0.8106 27.202
NCI-H2135 GDSC2 1.5406 6.0366 0.2957 24.6848
PaCa-3 GDSC2 1.549 4.9362 0.7927 21.9712
NCI-H1184 CTRP2 1.6561 16.2867 -3.5115 36.8027
SHP-77 GDSC2; CTRP2; CTRP1 1.6669 3.2322 1.6571 23.5905
NCI-H446 GDSC2 1.6906 6.0734 0.4284 23.3844
NCI-H2087 GDSC2; CTRP2 1.7234 4.9719 1.4672 24.0665
EBC-1 GDSC2; CTRP2; CTRP1 1.8184 3.3251 1.8087 22.5829
NCI-H1573 GDSC2; CTRP2; CTRP1 1.8323 5.0527 1.5654 23.3821
LK-2 GDSC2 1.9969 7.6026 -0.0028 24.3965
NCI-H290 GDSC2 2.0082 8.1174 -0.2427 25.4873
SW1573 GDSC2; CTRP2 2.0795 6.111 1.511 22.8315
NCI-H2347 GDSC2 2.0994 7.9137 -0.0583 24.2849
SBC-1 GDSC2 2.1021 4.1752 1.6893 14.5361
BEN GDSC2; CTRP2; CTRP1 2.1514 4.915 1.9477 21.04
NCI-H810 GDSC2; CTRP2; CTRP1 2.2155 5.307 1.9149 20.9603
NCI-H1693 GDSC2; CTRP2 2.229 4.8822 2.0399 20.4727
Lu-165 GDSC2 2.304 4.5313 1.7468 13.3884
COR-L105 GDSC2; CTRP2 2.3323 5.4713 1.9943 20.321
NCI-H2795 GDSC2 2.3746 4.32 1.9121 12.127
NCI-H1688 GDSC2 2.3905 7.7986 0.2668 21.6124
NCI-H2227 GDSC2 2.4088 6.7809 0.7829 18.7334
HCC2935 CTRP2; CTRP1 2.4436 5.1737 2.2007 19.2393
NCI-H1944 GDSC2; CTRP2; CTRP1 2.4707 5.2902 2.1981 19.1664
NCI-H2722 GDSC2 2.5067 5.7375 1.382 14.8487
HCC366 GDSC2; CTRP2 2.5701 8.8143 0.9154 23.6039
VMRC-LCD GDSC2; CTRP2; CTRP1 2.6574 5.9984 2.175 18.6991
NCI-H358 GDSC2; CTRP2; CTRP1 2.6623 5.1372 2.4491 17.6806
ABC-1 GDSC2 2.668 6.2911 1.2624 15.0158
NCI-H1563 GDSC2; CTRP2 2.8059 5.4674 2.5116 17.0211
NCI-H2081 GDSC2; CTRP2; CTRP1 2.8542 6.3441 2.2597 17.8194
NCI-H2810 GDSC2 2.8665 7.1027 1.0397 15.6917
NCI-H2731 GDSC2 2.8925 6.0119 1.6042 12.1749
NCI-H2804 GDSC2 2.9631 7.8821 0.7363 17.1396
LC-2/ad GDSC2 2.9738 4.8714 2.2409 7.9287
NCI-H2085 GDSC2 3.0272 8.2781 0.5941 17.7317
RERF-LC-Sq1 GDSC2 3.0594 8.2386 0.6416 17.3668
Sq-1 CTRP2; CTRP1 3.0797 4.8318 2.9764 14.5173
NCI-H1650 GDSC2 3.0927 5.4964 2.0383 8.8179
SK-MES-1 GDSC2; CTRP2 3.1243 6.5759 2.4559 16.3206
NCI-H1581 GDSC2; CTRP2 3.144 5.9674 2.7109 15.2958
NCI-H1838 GDSC2; CTRP2 3.1598 6.7025 2.4418 16.2778
NCI-H441 GDSC2; CTRP2; CTRP1 3.2123 7.2243 2.276 16.7793
PC-14 GDSC2 3.2404 7.7656 1.0318 14.5688
HCC95 CTRP2 3.2926 7.876 2.0689 17.3786
A-427 GDSC2 3.3149 9.2536 0.3502 18.1629
NCI-H1734 GDSC2; CTRP2 3.3216 9.0108 1.0106 15.9837
HCC2279 CTRP2 3.3495 10.792 0.7489 22.1801
LUDLU-1 CTRP2 3.3541 6.6765 2.6564 14.9212
NCI-H2373 GDSC2 3.4037 7.4039 1.3487 12.1844
NCI-H1975 GDSC2; CTRP1 3.4454 5.6326 3.1541 16.2016
NCI-H740 GDSC2 3.4488 10.4488 -0.1363 20.2113
HARA [Human squamous cell lung carcinoma] GDSC2; CTRP2; CTRP1 3.4599 7.3769 2.4627 15.4007
DV-90 CTRP2; CTRP1 3.4633 6.3852 2.8909 13.7179
IA-LM GDSC2 3.4639 8.2065 0.9969 14.1137
HCC33 GDSC2; CTRP1 3.5209 5.5832 3.2526 15.4588
HCC78 GDSC2; CTRP2; CTRP1 3.5757 7.738 2.4162 15.2898
Calu-3 GDSC2; CTRP2; CTRP1 3.6397 5.4882 3.4129 11.2435
NCI-H647 GDSC2; CTRP2 3.6643 7.9959 2.3851 15.1926
NCI-H2591 GDSC2 3.7295 9.3412 0.6449 15.3636
NCI-H1568 GDSC2; CTRP2; CTRP1 3.7624 6.7412 3.0528 12.287
HCC44 GDSC2; CTRP2; CTRP1 3.7903 6.7303 3.0862 12.0824
NCI-H82 GDSC2; CTRP1 3.8131 7.0152 2.9834 15.7635
NCI-H2073 CTRP1 3.8254 7.3566 2.8408 27.1787
EMC-BAC-1 GDSC2 3.8337 11.037 -0.1179 19.0163
SK-LU-1 GDSC2; CTRP2; CTRP1 3.8935 7.0375 3.0546 11.9427
NCI-H2444 GDSC2 3.8975 8.0223 1.4325 10.3219
NCI-H322M GDSC2 3.9105 7.7374 1.5835 9.3692
NCI-H1915 GDSC2; CTRP2; CTRP1 3.998 6.5928 3.3596 10.4623
NCI-H226 GDSC2 4.0374 8.3734 1.3648 10.3723
LCLC-97TM1 GDSC2; CTRP2; CTRP1 4.0682 7.0261 3.2351 10.7809
NCI-H2818 GDSC2 4.1559 7.2322 2.0107 6.1619
SBC-3 GDSC2 4.1987 7.8873 1.7222 7.8197
LC-1/sq GDSC2 4.2412 9.0536 1.1815 10.9503
LXF 289 GDSC2; CTRP2; CTRP1 4.2539 9.538 2.2051 14.53
NCI-H2595 GDSC2 4.2733 8.6499 1.4032 9.5631
NCI-H2461 GDSC2 4.3605 6.9991 2.2601 4.2339
NCI-H1755 GDSC2; CTRP1 4.405 7.0581 3.5516 11.0092
HCC1195 CTRP1 4.4258 7.6611 3.2819 20.6077
EMC-BAC-2 GDSC2 4.4442 7.5574 2.0506 5.3057
Calu-6 GDSC2; CTRP2; CTRP1 4.4549 6.0445 4.0689 6.4703
NCI-H841 GDSC2; CTRP2; CTRP1 4.478 7.1442 3.5809 8.3861
NCI-H2803 GDSC2 4.4797 7.435 2.1317 4.7562
NCI-H1437 GDSC2; CTRP1 4.5539 7.0821 3.6831 9.8829
NCI-H3122 GDSC2 4.5782 7.8597 1.9951 5.3652
LK2 CTRP2 4.6057 10.4421 2.0744 14.2882
NCI-H596 GDSC2; CTRP1 4.6295 6.6541 3.961 8.2139
SW1271 GDSC2 4.6366 9.5752 1.2116 9.84
HCC1588 CTRP2 4.65 10.9463 1.8625 15.0377
NCI-H1792 GDSC2; CTRP2; CTRP1 4.6521 7.6476 3.4996 8.3248
RERF-LC-KJ GDSC2; CTRP1 4.6601 6.2059 4.2026 6.873
NCI-H1395 CTRP2 4.6801 9.3702 2.673 11.6918
NCI-H2228 GDSC2 4.6836 10.6847 0.7045 12.5785
NCI-H2009 GDSC2; CTRP2; CTRP1 4.7406 9.6495 2.5875 11.9167
COR-L51 CTRP2; CTRP1 4.7809 6.1363 4.3538 4.5107
NCI-H2369 GDSC2 4.8006 11.5145 0.383 14.0079
NCI-H1355 GDSC2; CTRP2; CTRP1 4.8213 8.9143 3.0244 9.9393
KNS-62 GDSC2; CTRP2; CTRP1 4.884 5.8809 4.575 3.3635
NCI-H2291 GDSC2; CTRP2 4.933 11.8736 0.9341 12.8701
NCI-H322 CTRP2 4.961 6.2699 4.4602 3.6574
COR-L23 GDSC2; CTRP1 4.9834 5.6925 4.7609 3.0047
Lu-99 CTRP2; CTRP1 4.9882 8.0703 3.5907 7.2299
NCI-H2286 CTRP2; CTRP1 5.0637 9.008 3.1874 8.7661
NCI-H520 GDSC2; CTRP2 5.0943 8.3113 3.5616 7.1385
NCI-H513 GDSC2 5.1427 10.6336 1.0496 9.6521
HCC1438 CTRP2 5.1541 7.9534 3.7911 6.0583
HCC1359 CTRP1 5.1881 6.0008 4.7958 3.8179
Lu-99A GDSC2 5.2198 9.165 1.7897 5.3499
NCI-H1869 GDSC2; CTRP2 5.3026 12.4095 1.6867 14.4026
LCLC-103H GDSC2; CTRP2; CTRP1 5.3487 7.1336 4.3608 3.3013
CAL-12T GDSC2; CTRP2; CTRP1 5.3495 7.7118 4.0729 4.5054
NCI-H2110 GDSC2; CTRP2; CTRP1 5.3511 8.0217 3.9196 5.1452
NCI-H2126 CTRP2; CTRP1 5.3569 10.5751 2.6485 10.4376
ChaGo-K-1 GDSC2; CTRP2; CTRP1 5.3633 9.7233 3.0795 8.6385
NCI-H2122 GDSC2; CTRP2; CTRP1 5.3643 9.2609 3.3113 7.6683
NCI-H1793 GDSC2; CTRP2; CTRP1 5.366 17.2852 -0.6984 22.3599
SBC-5 GDSC2; CTRP2 5.392 8.9858 3.4712 6.9482
LC-1/sq-SF CTRP2; CTRP1 5.4486 9.3897 3.3152 7.4964
HCC827 GDSC2; CTRP2; CTRP1 5.4522 8.1352 3.9437 4.8612
HOP-62 GDSC2; CTRP2 5.4738 7.101 4.474 2.6125
DMS 273 GDSC2; CTRP2; CTRP1 5.5389 8.8099 3.6758 5.827
NCI-H522 GDSC2; CTRP2; CTRP1 5.6176 7.1148 4.5718 1.984
HCC2108 CTRP2; CTRP1 5.6219 8.0239 4.1295 3.796
RERF-LC-A1 CTRP2 5.6276 8.1631 4.065 4.054
NCI-H23 GDSC2; CTRP2; CTRP1 5.654 9.5556 3.3949 6.7969
NCI-H2869 GDSC2 5.7622 7.8885 2.613 0.7504
NCI-H2405 GDSC2; CTRP2; CTRP1 5.8372 9.8679 3.3804 6.544
NCI-H460 GDSC2; CTRP2; CTRP1 5.94 7.5668 4.5697 1.56
NCI-H1373 CTRP2; CTRP1 5.9862 9.2886 3.7754 4.675
NCI-H650 GDSC2; CTRP2; CTRP1 6.0844 7.9234 4.4938 1.6767
Lu-65 GDSC2; CTRP2; CTRP1 6.1074 10.096 3.4681 5.7452
A-549 GDSC2; CTRP2; CTRP1 6.1222 12.48 2.304 10.4633
NCI-H1781 GDSC2; CTRP1 6.1943 12.0209 2.5857 11.5605
Calu-1 CTRP2 6.2921 10.3992 3.4521 5.5279
NCI-H1666 GDSC2; CTRP2; CTRP1 6.4668 22.1721 -2.2481 24.3197
NCI-H727 GDSC2; CTRP2; CTRP1 6.4733 13.0387 2.2917 9.9273
NCI-H1703 GDSC2; CTRP2 6.4898 10.8153 3.3885 5.4939
EPLC-272H GDSC2; CTRP2; CTRP1 6.4934 13.5133 2.0729 10.7555
MOR/CPR CTRP2 6.5181 7.5663 4.8637 0.1979
EKVX GDSC2; CTRP2 6.7721 17.8213 0.1538 17.1757
NCI-H292 GDSC2; CTRP2 6.8011 10.8556 3.5771 4.3192
RERF-LC-MS GDSC2; CTRP2 6.8293 12.6007 2.7612 7.5084
RERF-LC-Ad1 CTRP2 6.9375 16.5378 0.1129 12.6242
NCI-H2023 GDSC2; CTRP2; CTRP1 6.9606 14.0157 2.1666 9.6479
NCI-H661 GDSC2; CTRP2; CTRP1 6.9974 15.5157 1.4599 12.2703
NCI-H838 GDSC2; CTRP2 7.0956 10.6559 3.8512 2.9277
HCC1171 CTRP2 7.2886 17.4497 0.7237 14.4237
RERF-LC-Ad2 CTRP2 7.3307 11.8115 3.4641 4.1008
NCI-H2030 GDSC2; CTRP2; CTRP1 7.3719 12.1619 3.3275 4.5676
DMS 114 GDSC2; CTRP2 7.4909 9.3318 4.6016 0.3545
NCI-H1339 CTRP2 7.5582 10.0392 4.3584 0.8839
NCI-H2172 GDSC2; CTRP2; CTRP1 7.6418 14.0299 2.6243 6.9104
NCI-H1651 GDSC2; CTRP2 7.9464 10.3813 4.3954 0.5985
NCI-H1299 GDSC2; CTRP2; CTRP1 8.0832 12.8573 3.4316 3.4093
NCI-H196 GDSC2; CTRP2 8.1163 16.1682 1.9221 8.9135
NCI-H1623 GDSC2; CTRP2 8.9935 21.2639 0.075 13.9957
Hs 888.Lu CTRP2 6.669 11.8429 3.0163 6.7268
⏷ Show the Full List of 221 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 4.1239 7.1786 2.0142 6.2125
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 -0.2176 4.3273 -0.4978 36.9212
SYO-1 CTRP2 5.9443 14.2034 1.3092 14.6286
H-STS CTRP2 6.5068 7.3085 4.9514 0.0683
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.3562 8.338 1.9211 17.7935
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 6.7621 8.3624 4.6627 0.5429
Yamato-SS CTRP2 6.7938 12.8511 2.615 8.1418
TE 441.T GDSC2; CTRP2 0.1102 5.3091 -0.3831 35.401
Rh41 GDSC2; CTRP2 1.4246 12.3245 -1.8439 34.5468
EW-8 GDSC2 2.1759 5.0298 1.3926 15.9998
Hs 633.T GDSC2 3.1417 5.3407 2.1587 7.906
HT-1080 GDSC2; CTRP2; CTRP1 3.1789 10.2615 0.8411 22.2798
MFH-ino GDSC2 3.3853 10.7891 -0.359 21.4405
SK-LMS-1 GDSC2; CTRP2 3.7246 6.7042 3.0299 12.476
SW872 GDSC2 3.8043 8.0306 1.3565 11.0259
RD GDSC2; CTRP2 3.8424 9.4583 1.8605 16.8468
SW684 GDSC2 3.8594 7.2609 1.7805 8.2865
KYM-1 GDSC2; CTRP2 4.1947 6.9926 3.3764 9.8984
Rh30 GDSC2 4.3174 8.9415 1.2924 10.1137
GCT GDSC2; CTRP2 4.5545 6.1763 4.111 6.0483
VA-ES-BJ GDSC2 4.5899 9.9771 0.9827 11.2553
TE 617.T CTRP2 5.1143 6.0725 4.6963 2.3436
A-204 GDSC2; CTRP2 5.145 6.9712 4.2743 4.0495
G-401 GDSC2; CTRP2; CTRP1 5.2111 10.3724 2.6294 10.7961
Hs 729.T CTRP2 5.4641 7.6372 4.2007 3.7665
RKN GDSC2; CTRP2; CTRP1 6.1187 15.9491 0.5773 16.9217
STS-0421 GDSC2 6.1234 8.4675 2.5445 0.748
BT-16 CTRP2 6.2482 10.7982 3.2264 6.514
BT-12 CTRP2 6.2907 7.2861 4.8751 0.2649
MES-SA GDSC2; CTRP2 6.3327 13.1332 2.1403 10.7579
G-402 GDSC2; CTRP2 6.5475 12.0016 2.8536 7.5625
SW982 GDSC2; CTRP2 6.5666 9.4896 4.0669 2.7237
Tm87-16 CTRP2 7.28 8.8773 4.6848 0.2723
SK-UT-1 GDSC2; CTRP2 7.5936 11.4563 3.7779 2.6794
TTC-709 CTRP2 8.1579 15.8945 2.079 8.2804
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 7.0288 17.2478 0.6311 15.1624
JHOC-5 CTRP2; CTRP1 -0.3002 2.8997 -0.365 36.8427
RMUG-S CTRP1 0.8604 3.7235 0.771 60.491
RMG-I GDSC2; CTRP2; CTRP1 1.1602 4.8861 0.8743 27.9007
OVISE GDSC2; CTRP2 1.3014 4.7886 1.0516 26.8422
OV-90 GDSC2; CTRP2; CTRP1 1.4672 5.8875 0.922 26.7723
SNU-119 CTRP2 1.6022 3.255 1.5899 24.0292
JHOM-1 CTRP2; CTRP1 1.7163 7.551 0.5754 27.2002
OVCAR-4 GDSC2; CTRP1 2.1329 7.1723 1.1681 30.0345
Caov-4 GDSC2 2.4171 5.4578 1.4304 14.8756
OVCAR-5 GDSC2; CTRP2 3.2926 4.7209 3.2278 12.968
JHOS-4 GDSC2; CTRP1 3.6056 5.3943 3.4054 14.428
OVMANA CTRP1 3.6278 5.6351 3.3508 24.6872
OVKATE GDSC2; CTRP1 3.6723 8.4235 2.1925 20.1054
FU-OV-1 GDSC2; CTRP2 3.6834 9.0271 1.9165 17.0048
A2780 GDSC2; CTRP2; CTRP1 3.6846 6.0689 3.2514 11.7231
COV362 CTRP2; CTRP1 4.0978 8.6191 2.5081 13.6589
OVCAR-3 GDSC2 4.1069 9.3587 0.9301 12.7436
Caov-3 GDSC2; CTRP2; CTRP1 4.1966 8.9374 2.4463 13.6829
OC 314 GDSC2; CTRP2 4.2305 5.4921 4.0525 7.1477
OAW42 GDSC2; CTRP2; CTRP1 4.2733 5.5737 4.0695 6.9612
TYK-nu GDSC2; CTRP2; CTRP1 4.3312 7.0998 3.4602 9.227
ES-2 GDSC2 4.3547 9.592 1.0004 11.7192
TOV-21G GDSC2; CTRP2 4.7478 8.6378 3.0969 9.792
TOV-112D GDSC2 4.7562 12.761 -0.2621 17.2822
OV7 CTRP2; CTRP1 4.8497 5.9236 4.5213 3.6644
EFO-27 GDSC2; CTRP2; CTRP1 4.889 5.9254 4.5588 3.4171
OAW28 GDSC2; CTRP2 5.175 15.7236 -0.0764 20.8714
COV318 CTRP1 5.256 6.1975 4.7537 3.9195
SK-OV-3 GDSC2; CTRP2; CTRP1 5.4103 7.8792 4.038 4.5415
HEY A8 CTRP2; CTRP1 5.632 7.5429 4.3734 2.7728
COV434 CTRP2; CTRP1 5.667 12.0927 2.1413 11.9209
OVK18 GDSC2; CTRP2; CTRP1 5.7931 7.5893 4.4638 2.1666
COV644 CTRP2; CTRP1 5.8802 7.3805 4.6189 1.4443
SNU-840 CTRP2; CTRP1 5.9127 10.4972 3.1263 7.4682
IGROV-1 GDSC2; CTRP2; CTRP1 5.9512 8.8025 3.9873 3.8628
MCAS CTRP2 6.0783 9.0804 3.9415 3.8606
EFO-21 GDSC2; CTRP2; CTRP1 6.4843 8.9888 4.2469 2.1433
ONCO-DG-1 CTRP2 6.7406 10.8395 3.5454 4.5227
OV56 GDSC2; CTRP2 6.7558 11.0906 3.4363 4.9317
SNU-8 CTRP2 7.1232 8.2913 4.8338 0.0953
JHOS-2 GDSC2; CTRP2 7.2189 11.008 3.7643 3.1121
DOV13 GDSC2; CTRP2 7.3481 8.9872 4.6715 0.2744
OVSAHO CTRP2 7.7124 12.444 3.4039 3.8928
ES2 CTRP2 7.9665 13.3688 3.1341 4.5999
OVCAR-8 GDSC2; CTRP2; CTRP1 8.2808 16.2222 2.0041 8.3949
OVTOKO GDSC2; CTRP2 8.6787 15.3555 2.6531 5.5535
Kuramochi GDSC2; CTRP2 9.3391 21.0902 0.3909 12.5339
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC2; CTRP1 2.7992 5.1935 2.5834 21.289
NCI-H2452 GDSC2 3.3593 6.8337 1.5971 10.7842
MPP 89 GDSC2; CTRP2 3.4599 5.7646 3.1241 12.8398
NCI-H28 GDSC2; CTRP2; CTRP1 3.8972 7.1436 3.0102 12.111
IST-Mes1 GDSC2 4.9888 7.9288 2.2146 3.3935
NCI-H2052 GDSC2; CTRP2; CTRP1 5.3436 9.081 3.3843 7.4017
ACC-MESO-1 CTRP2 5.4139 10.1894 2.8878 9.3412
JL-1 CTRP2 7.6545 9.3325 4.6647 0.2026
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H660 GDSC2; CTRP2 -3.4605 -1.2079 -3.4609 57.6424
PC-3 GDSC2 2.4757 6.0135 1.2191 15.9413
VCaP GDSC2; CTRP2 3.192 6.4852 2.5639 15.7199
PaCa-3 CTRP2; CTRP1 4.0122 5.1532 3.9178 8.2897
LNCaP clone FGC GDSC2; CTRP2 4.6372 14.1599 0.2488 20.9367
DU145 GDSC2; CTRP2 6.2888 11.0784 3.1187 6.8896
22Rv1 GDSC2; CTRP2 8.0298 18.4133 0.7847 13.074
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 4.0361 7.3384 1.8733 7.2805
YD-15 CTRP2 5.3232 6.7795 3.6547 0.7657
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 3.9204 9.0851 0.9226 13.2761
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 GDSC2 -2.1431 0.3268 -2.1604 54.7248
OCUM-1 GDSC2 0.128 3.6306 -0.2527 33.8481
GSS CTRP2 0.2714 1.9729 0.2688 32.8466
SK-GT-2 GDSC2 0.2899 2.9963 0.0959 31.3945
HuG1-N CTRP2 1.298 4.8317 1.0376 26.9011
HSC-39 GDSC2 1.5513 3.3837 1.3724 18.7133
RERF-GC-1B GDSC2 1.6082 7.0812 -0.1247 26.4809
AGS GDSC2; CTRP2; CTRP1 2.0505 8.0506 0.718 25.7396
TGBC11TKB GDSC2 2.1502 5.6835 1.0639 18.0445
HGC-27 GDSC2; CTRP2 2.1864 3.658 2.1719 20.1518
SNU-16 GDSC2; CTRP2 2.2799 4.3953 2.1922 19.7796
NCI-N87 GDSC2; CTRP2 2.3071 7.5812 1.1835 23.3682
SNU-1 GDSC2; CTRP2 2.3318 9.2264 0.4885 25.7238
GCIY GDSC2 2.4479 6.2173 1.094 16.7852
SNU-620 CTRP2 3.0375 7.888 1.805 19.0632
Hs 746.T GDSC2; CTRP2 3.0519 6.1446 2.5467 16.1762
SNU-719 CTRP2 3.2117 12.4554 -0.1885 25.5821
NUGC-4 GDSC2; CTRP2; CTRP1 3.3137 7.7217 2.1599 16.9681
TMK-1 GDSC2 3.6524 5.5099 2.4896 4.3834
MKN28 GDSC2 3.9188 8.2983 1.312 10.9934
MKN7 GDSC2; CTRP2; CTRP1 4.2504 7.3921 3.2432 10.3041
KE-39 CTRP2 4.2836 9.4243 2.2882 14.1281
MKN1 GDSC2; CTRP2 4.3374 6.1186 3.9159 7.3808
MKN74 CTRP2; CTRP1 4.6208 7.2559 3.6621 7.7231
RF-48 GDSC2 4.6898 14.3122 -1.079 20.9464
IM95 GDSC2; CTRP2 4.8002 9.0184 2.954 10.2758
KATO III GDSC2; CTRP2 4.8928 6.3504 4.3575 4.2354
SNU-5 GDSC2; CTRP2 5.1734 8.0207 3.003 3.5093
Fu97 GDSC2; CTRP2; CTRP1 5.2766 9.5502 3.0948 8.7384
SCH GDSC2 5.2799 14.6144 -0.7873 18.3473
SH-10-TC CTRP2; CTRP1 5.4622 8.2041 3.9172 4.9542
SNU-216 CTRP2 5.7272 10.9409 2.7629 9.2873
GSU CTRP2 6.1673 6.8383 4.9912 0.0864
SNU-668 CTRP2 6.5197 12.4159 1.8022 6.6326
MKN45 GDSC2; CTRP2 6.8216 7.7462 4.9133 0.06
ECC12 GDSC2; CTRP2 6.8659 8.0532 4.8225 0.1637
SNU-601 CTRP2 7.2817 8.6626 4.7623 0.1518
23132/87 GDSC2; CTRP2 7.3392 12.4497 3.1729 5.1974
NUGC-3 GDSC2; CTRP2 9.0841 18.6379 1.3844 9.5678
LMSU CTRP2 9.0935 16.6109 2.3282 6.2496
SNG-M GDSC2; CTRP2; CTRP1 2.8725 6.524 2.2096 17.9577
SNU-685 CTRP2 7.7926 12.3917 3.4742 3.5531
SNU-1077 CTRP2 9.5608 19.1 1.4687 8.6965
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-133 GDSC2; CTRP2 0.2551 7.9985 -1.151 36.7812
ASH-3 GDSC2 1.8666 3.6244 1.6419 15.8106
HTC-C3 GDSC2 2.4236 4.9531 1.6748 13.3682
ML-1 [Human leukemia] GDSC2 2.7486 7.8501 0.564 18.799
KMH-2 GDSC2 3.8528 8.6627 1.0801 12.5429
IHH-4 GDSC2 3.9608 7.051 1.9593 6.9305
WRO GDSC2 4.1551 7.3426 1.9565 6.4939
SW579 CTRP2 4.4953 5.1242 4.4516 4.9002
8505C GDSC2; CTRP2 4.5366 8.8446 2.8046 11.4572
K5 GDSC2 4.5695 9.8184 1.0456 10.9465
TT2609-C02 GDSC2; CTRP2 4.6484 7.6447 3.4975 8.3418
CAL-62 GDSC2; CTRP2 5.0665 6.0008 4.6891 2.4751
B-CPAP GDSC2; CTRP2 6.3228 13.0124 2.1925 10.5679
BHT-101 GDSC2; CTRP2 6.3398 12.6201 2.3988 9.7193
CGTH-W-1 GDSC2; CTRP2 6.8948 8.3309 4.7321 0.3179
TT GDSC2; CTRP2 7.7076 16.1432 1.6584 10.4546
8305C GDSC2; CTRP2 10.5087 20.6249 1.3421 8.0474
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Ca9-22 GDSC2 0.3685 6.5992 -1.1459 35.9345
SCC-4 GDSC2; CTRP2 0.704 6.0924 0.0259 32.15
HO-1-N-1 GDSC2 0.792 3.8304 0.4071 27.3895
HO-1-u-1 GDSC2 1.1179 4.9 0.357 26.1648
JHU-029 GDSC2 1.3516 5.2448 0.4559 24.6344
SAS GDSC2 1.5631 3.6768 1.295 19.087
BICR 10 GDSC2 1.6204 6.0228 0.3819 23.9124
OSC-19 GDSC2 2.0899 4.4672 1.5543 15.3765
KON GDSC2 2.1006 5.166 1.2549 17.1061
PCI-15A GDSC2 2.1751 5.3272 1.2549 16.8226
DOK GDSC2 2.1814 8.9332 -0.4829 25.927
PCI-06A GDSC2 2.7197 7.59 0.6674 18.3208
CAL-27 GDSC2 2.7869 5.548 1.7367 11.7019
HSC-4 GDSC2; CTRP2 2.9457 5.8646 2.5335 16.5297
BB49-HNC GDSC2 3.0745 10.0521 -0.2515 21.8946
KOSC-2 GDSC2 3.0895 9.9237 -0.1746 21.4863
BB30-HNC GDSC2 3.1003 10.2797 -0.3433 22.2373
SCC-15 GDSC2 3.1098 9.2753 0.1667 19.7447
SAT [Human HNSCC] GDSC2 3.1463 7.4791 1.0952 14.4801
UPCI-SCC-090 GDSC2 3.1698 9.9735 -0.1315 21.0319
PCI-04B GDSC2 3.7835 5.6501 2.5165 3.9035
BICR 78 GDSC2 3.8491 9.9031 0.4597 16.0394
HSC-2 GDSC2; CTRP2; CTRP1 3.8656 7.6836 2.7295 13.3165
PE/CA-PJ15 GDSC2; CTRP2 3.9665 6.4721 3.3801 10.4633
NCI-H3118 GDSC2 4.2858 8.5666 1.453 9.2366
PCI-30 GDSC2 4.3823 10.9264 0.3632 15.1387
SCC-25 GDSC2; CTRP2 4.4048 12.4204 0.9132 19.1528
LB771-HNC GDSC2 4.4824 12.4087 -0.2943 18.1155
PE/CA-PJ49 CTRP2 4.5896 5.4225 4.4648 4.5708
CAL-33 GDSC2; CTRP2 4.6254 6.6469 3.9605 6.4858
PE/CA-PJ34 (clone C12) CTRP2 4.6256 7.387 3.6027 7.9576
PE/CA-PJ41 (clone D2) CTRP2 4.8736 11.3633 1.8484 14.6276
SNU-1214 CTRP2 5.2393 13.0221 0.6004 13.6498
SKN-3 GDSC2 5.314 12.0807 0.471 12.3851
BICR 56 CTRP2 5.341 11.1824 2.3319 11.7637
YD-10B CTRP2 5.3655 8.7515 2.7826 4.1678
FaDu GDSC2; CTRP2 5.4214 9.5831 3.1967 8.0413
OSC-20 GDSC2 5.4232 8.3318 2.2755 2.4697
SCC-9 GDSC2; CTRP2; CTRP1 5.472 9.3794 3.3391 7.354
JHU-022 GDSC2 5.507 14.9002 -0.7626 17.7273
SNU-46 CTRP2 6.2911 11.5756 2.0504 5.9307
JHU-011 GDSC2 6.3093 14.1678 0.1408 11.9845
HSC-3 GDSC2; CTRP2 6.7252 8.0778 4.757 0.3349
SNU-899 CTRP2 6.9152 8.0476 3.8114 0.0179
BICR 22 GDSC2; CTRP2 6.9159 14.9905 1.658 11.6625
BHY GDSC2; CTRP2 7.0364 12.172 3.1077 5.8455
SNU-1066 CTRP2 7.0579 12.1328 3.1405 5.6883
Detroit 562 GDSC2; CTRP2 7.0887 8.8502 4.6162 0.4883
BICR 18 CTRP2 7.226 16.0071 1.385 12.1831
BICR 16 CTRP2 7.5187 9.2939 4.6266 0.2997
SNU-1076 CTRP2 8.4968 18.4737 1.0765 11.407
BICR 6 CTRP2 8.8606 15.3915 2.7431 5.0389
SNU-1041 CTRP2 9.0663 16.8713 2.1931 6.7564
BICR 31 GDSC2; CTRP2 9.4525 21.6184 0.2147 12.9382
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMBC-2 CTRP2; CTRP1 1.2349 3.6631 1.176 26.6287
U-BLC1 CTRP2 1.5471 2.3089 1.547 24.3547
SW780 GDSC2 2.3131 4.009 1.9792 11.9791
TCCSUP GDSC2; CTRP2 2.539 4.333 2.4792 17.9609
SW1710 GDSC2 2.9575 5.079 2.1238 8.7162
HT-1197 GDSC2; CTRP2 3.2117 5.8862 2.8131 14.718
253J CTRP2 3.4571 7.4382 2.4325 15.5275
T24 GDSC2; CTRP2 4.0672 7.8777 2.8349 12.4023
5637 GDSC2; CTRP2; CTRP1 4.0865 7.5936 2.9884 11.7331
253J-BV CTRP2 4.2102 6.2384 3.7327 8.4358
RT-4 GDSC2; CTRP2; CTRP1 4.4687 13.5452 0.4092 20.7651
BC-3C CTRP2 4.7508 5.495 4.6098 3.5671
CAL-29 GDSC2; CTRP2 4.8503 7.4834 3.7609 6.8069
BFTC-905 GDSC2; CTRP2 4.952 5.6469 4.7513 2.4834
HT-1376 GDSC2; CTRP2; CTRP1 5.1195 10.9663 2.2557 12.5031
UM-UC-1 CTRP2 5.1709 6.5877 4.4879 3.1023
647V GDSC2 5.4242 12.9522 0.1263 13.876
UM-UC-3 GDSC2; CTRP2; CTRP1 5.4318 12.0529 1.9712 13.0381
639V GDSC2; CTRP2 6.373 7.5404 4.8123 0.3748
KU-19-19 GDSC2; CTRP2 6.5691 7.9506 4.7385 0.4553
JMSU-1 CTRP2 7.2895 8.6183 4.7807 0.127
RT-112 GDSC2; CTRP2 7.3881 8.9675 4.6941 0.2253
J82 GDSC2; CTRP2 8.1924 13.6551 3.1374 4.3417
VM-CUB-1 CTRP2 8.7719 14.801 2.9564 4.3836
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC-YIK GDSC2 -2.1827 -0.2925 -2.1855 55.2052
SW954 GDSC2 -0.7828 5.9906 -2.09 44.1327
NT2-D1 GDSC2 -0.5637 4.1687 -1.1768 41.0389
PA-1 GDSC2 0.7179 7.5189 -1.2068 34.5126
DoTc2 4510 GDSC2 1.4036 4.7879 0.7033 23.0773
Ca Ski GDSC2 1.6192 4.3108 1.124 19.8065
CAL-39 GDSC2 1.9554 4.1649 1.5384 16.0193
OVMIU GDSC2 2.0318 5.9338 0.8302 19.8422
HEC-1 GDSC2 2.1125 4.7104 1.4719 15.7739
DSH1 GDSC2 2.333 6.598 0.8011 18.8991
ME-180 GDSC2 2.5044 5.0969 1.6864 13.0011
JEG-3 GDSC2 2.5052 9.8812 -0.6609 25.5584
JHOS-3 GDSC2 2.5808 4.6251 1.9828 10.9113
UWB1.289 GDSC2 2.9764 5.4931 1.9364 9.8289
LB831-BLC GDSC2 3.0031 6.6167 1.4018 13.07
OVCA433 GDSC2 3.0818 4.9756 2.2873 7.2837
OVCA420 GDSC2 3.0997 11.2741 -0.8408 24.3828
C-4-I GDSC2 3.119 7.732 0.9456 15.4459
ACC-OV7 GDSC2 3.1454 7.024 1.3218 13.1171
OMC-1 [Human cervical carcinoma] GDSC2 3.4055 5.8395 2.1321 7.2925
OV17R GDSC2 3.5477 5.8889 2.2214 6.3377
SiHa GDSC2 3.568 5.8605 2.2514 6.0949
SKG-IIIa GDSC2 3.7168 7.4616 1.5713 9.9488
SKN GDSC2 3.9777 9.7186 0.6523 14.6435
BPH-1 GDSC2 4.0901 11.1607 0.0229 17.629
SW756 GDSC2 4.2637 12.8392 -0.6764 20.3823
C-33 A GDSC2 4.2812 10.6608 0.4181 15.1093
JAR GDSC2 4.4756 9.0845 1.3363 9.4834
MS751 GDSC2 4.4768 15.3776 -1.7726 24.0209
PEO1 GDSC2 4.492 8.3265 1.7149 7.2043
KGN GDSC2 4.6945 9.7206 1.1817 9.8815
NCC-IT GDSC2 4.7218 11.4997 0.3329 14.4553
SW962 GDSC2 4.9504 8.2572 2.0432 4.4007
HT-3 GDSC2 5.0305 15.8674 -1.59 22.036
SiSo GDSC2 5.0541 12.5985 0.0361 15.153
PWR-1E GDSC2 5.1653 12.2856 0.268 13.75
NEC8 GDSC2 5.3172 14.7403 -0.8218 18.4051
HEY GDSC2 5.9919 9.2117 2.1922 2.2016
HeLa GDSC2; CTRP2 6.4426 7.3194 4.9239 0.118
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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