Details of the Drug

General Information of Drug (ID: DML3OYH)

Drug Name
TriMixDC
Synonyms Dendritic cell vaccine (melanoma), Vrije Universiteit Brussel; TriMixDC (melanoma, intrademal), Universite Libre de Bruxelles
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Investigative [1]
Drug Type
Vaccine
Cross-matching ID
TTD ID
D04PFD

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CD70 antigen (CD27-L) TTNCIE0 CD70_HUMAN Not Available [1]
TNF related activation protein (CD40LG) TTIJP3Q CD40L_HUMAN Not Available [1]
Toll-like receptor 4 (TLR4) TTISGCA TLR4_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Melanoma
ICD Disease Classification 2C30
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
TNF related activation protein (CD40LG) DTT CD40LG 8.02E-01 -0.13 -0.7
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Characterization of CD8+ T-cell responses in the peripheral blood and skin injection sites of melanoma patients treated with mRNA electroporated autologous dendritic cells (TriMixDC-MEL). Biomed Res Int. 2013;2013:976383.