General Information of Drug (ID: DML44FR)

Drug Name
AR-42
Synonyms
AR-42; 935881-37-1; OSU-HDAC42; AR 42; (S)-HDAC-42; (S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide; UNII-E0GG29V0AQ; (S)-HDAC 42; E0GG29V0AQ; AR42; HDAC-42; AR-42 (HDAC-42); N-hydroxy-4-{[(2S)-3-methyl-2-phenylbutanoyl]amino}benzamide; N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide; AR-42 (OSU-HDAC42); AC1OCFYN; cc-20; OSU-HDAC 42; MLS006011089; CHEMBL191482; SCHEMBL2348844; OSU-42; DTXSID4042678; NOCAS_42678; CTK8C1969; AOB3995; N-Hydroxy-4-(3-methyl-2-(S)phenyl-butyrylamino)benzamide; MolPort-009-019-571
Indication
Disease Entry ICD 11 Status REF
Chronic lymphocytic leukaemia 2A82.0 Phase 1/2 [1]
Multiple myeloma 2A83 Phase 1/2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C18H20N2O3
Canonical SMILES
CC(C)C(C1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)C(=O)NO
InChI
1S/C18H20N2O3/c1-12(2)16(13-6-4-3-5-7-13)18(22)19-15-10-8-14(9-11-15)17(21)20-23/h3-12,16,23H,1-2H3,(H,19,22)(H,20,21)/t16-/m0/s1
InChIKey
LAMIXXKAWNLXOC-INIZCTEOSA-N
Cross-matching ID
PubChem CID
6918848
CAS Number
935881-37-1
UNII
E0GG29V0AQ
DrugBank ID
DB12707
TTD ID
D07KDI
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 -0.43 3.145 -0.9314 37.392
ES5 GDSC1 -4.5018 -2.0233 -4.5069 81.3863
CADO-ES1 GDSC1 -4.0131 -2.2173 -4.0137 78.3168
EW-18 GDSC1 -3.5282 -1.4752 -3.5316 72.4207
EW-1 GDSC1 -3.4931 -1.3604 -3.4977 71.8886
ES7 GDSC1 -3.4301 -1.7492 -3.4309 71.8174
CHSA0108 GDSC1 -3.1776 -0.4627 -3.2053 67.3782
SK-PN-DW GDSC1 -2.7623 0.6301 -2.8705 61.893
ES1 GDSC1 -2.7498 -0.9199 -2.7534 63.5294
TC-71 GDSC1 -2.7371 -1.1341 -2.7384 63.5053
EW-11 GDSC1 -2.5223 -0.5522 -2.53 60.6891
U2OS GDSC1 -2.3184 -0.0995 -2.338 58.0943
NOS-1 [Human HNSCC] GDSC1 -2.256 0.6836 -2.3386 56.8972
EW-7 GDSC1 -2.161 0.4684 -2.2147 56.0105
MHH-ES-1 GDSC1 -2.1253 -0.5705 -2.1278 55.9725
EW-3 GDSC1 -1.984 1.1707 -2.1174 53.7545
EW-13 GDSC1 -1.6884 3.7725 -2.512 50.371
ES8 GDSC1 -1.6039 2.4969 -2.0049 49.6058
EW-16 GDSC1 -1.4087 0.9558 -1.4719 47.2011
ES6 GDSC1 -0.2514 4.0662 -1.0878 36.843
A-673 GDSC1 -0.182 2.3794 -0.4202 33.1572
SK-ES-1 GDSC1 0.5181 5.2309 -0.8002 30.9868
SJSA-1 GDSC1 0.5497 5.4467 -0.8682 31.1503
HuO9 GDSC1 0.8044 3.3751 0.3061 22.7816
EW-24 GDSC1 1.1071 4.7111 0.0253 23.1376
NY GDSC1 1.1501 5.6202 -0.3646 25.3795
ES4 GDSC1 1.2758 7.0493 -0.942 27.9293
HuO-3N1 GDSC1 2.4121 7.2191 -0.0289 17.9284
CHSA0011 GDSC1 3.0401 8.8292 -0.3295 17.6323
CAL-72 GDSC1 3.0412 5.3983 1.3612 5.6817
HOS GDSC1 3.6173 5.989 1.452 3.6497
G-292 clone A141B1 GDSC1 4.0166 11.4842 -0.9089 17.9174
H-EMC-SS GDSC1 4.2516 9.1301 0.3886 9.5259
CAL-78 GDSC1 4.264 11.0688 -0.5308 15.1694
SaOS-2 GDSC1 4.2893 6.3982 1.6289 1.5023
MG-63 GDSC1 4.6722 6.2898 1.8302 0.3876
CHSA8926 GDSC1 4.6757 6.3137 1.823 0.406
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 144 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 -4.5816 -2.998 -4.5817 84.8646
Namalwa GDSC1 -5.642 -3.106 -5.6443 90.0025
Ku812 GDSC1 -5.3531 -4.2983 -5.3531 93.7525
MOLT-13 GDSC1 -5.3009 -3.6109 -5.301 90.9557
CA46 GDSC1 -5.2286 -2.0964 -5.2425 84.9521
SU-DHL-10 GDSC1 -5.1815 -3.6704 -5.1816 90.6752
EoL-1 GDSC1 -4.9706 -1.6625 -4.9936 82.4253
CTB-1 GDSC1 -4.9304 -0.7416 -5.012 79.124
ALL-PO GDSC1 -4.9159 -3.3476 -4.916 88.1534
SR GDSC1 -4.7277 -3.0195 -4.7278 85.9414
SU-DHL-5 GDSC1 -4.6015 -3.1535 -4.6015 85.4301
P30/OHK GDSC1 -4.5597 -3.3417 -4.5597 85.531
Karpas-45 GDSC1 -4.5279 -3.3229 -4.5279 85.2081
SU-DHL-16 GDSC1 -4.4932 -3.6823 -4.4932 85.4166
WIL2 NS GDSC1 -4.4544 -2.1874 -4.4572 81.6103
SU-DHL-8 GDSC1 -4.4277 -2.5983 -4.4282 82.6289
MOLP-8 GDSC1 -4.321 -1.9091 -4.326 79.8992
RPMI-8402 GDSC1 -4.2864 -2.5525 -4.2867 81.4093
697 GDSC1 -4.2238 -2.506 -4.2242 80.7791
KOPN-8 GDSC1 -4.2071 -2.4261 -4.2076 80.4536
QIMR-WIL GDSC1 -4.1813 -1.4 -4.1957 77.4762
OCI-M1 GDSC1 -4.1726 -2.9871 -4.1726 81.1817
NB4 GDSC1 -4.1151 -2.9971 -4.1151 80.5832
MY-M12 GDSC1 -4.0658 -2.9486 -4.0658 79.9953
NKM-1 GDSC1 -4.0353 -2.0577 -4.0368 78.1609
BE-13 GDSC1 -4.0008 -2.5444 -4.0009 78.7958
RS4;11 GDSC1 -3.9814 -2.477 -3.9815 78.4963
HEL GDSC1 -3.9487 -1.9373 -3.9505 77.1536
MOLM-13 GDSC1 -3.877 -0.9262 -3.9026 74.0853
SIG-M5 GDSC1 -3.8419 -2.0118 -3.8429 76.3492
ALL-SIL GDSC1 -3.8377 -2.7193 -3.8377 77.2426
JSC-1 GDSC1 -3.8197 -2.2836 -3.8199 76.5787
Daudi GDSC1 -3.806 0.4831 -3.9655 70.0081
CESS GDSC1 -3.7639 -2.5611 -3.7639 76.2833
OCI-AML-5 GDSC1 -3.7545 -1.7747 -3.7566 75.091
RPMI-6666 GDSC1 -3.7291 -0.9624 -3.749 73.0785
VAL GDSC1 -3.7227 -0.9789 -3.7418 73.0691
SU-DHL-6 GDSC1 -3.6975 -2.2372 -3.6976 75.2385
Karpas-620 GDSC1 -3.6338 -1.4268 -3.6389 73.3142
SU-DHL-4 GDSC1 -3.6192 -2.0895 -3.6194 74.2306
NU-DUL-1 GDSC1 -3.5774 -2.0799 -3.5776 73.7693
KMS-12-BM GDSC1 -3.551 -2.1355 -3.5511 73.5333
GDM-1 GDSC1 -3.5259 -0.8359 -3.5458 71.1526
MHH-PREB-1 GDSC1 -3.4959 -0.9562 -3.5104 71.1476
HAL-01 GDSC1 -3.4816 -1.5239 -3.4842 72.0456
CCRF-CEM GDSC1 -3.4813 -2.2148 -3.4813 72.8007
SUP-M2 GDSC1 -3.4752 -0.7354 -3.4982 70.5139
SUP-B15 GDSC1 -3.4523 -1.999 -3.4525 72.3111
OCI-Ly19 GDSC1 -3.4521 -1.7226 -3.4531 72.0192
YT GDSC1 -3.4509 -1.608 -3.4526 71.858
NALM-6 GDSC1 -3.437 -1.9907 -3.4372 72.1328
BL-41 GDSC1 -3.3844 -2.2194 -3.3845 71.6647
ST486 GDSC1 -3.382 -0.5346 -3.4125 69.3123
MLMA GDSC1 -3.3503 -1.7334 -3.3509 70.9355
VL51 GDSC1 -3.3381 -1.8254 -3.3385 70.8836
KE-37 GDSC1 -3.2964 -1.556 -3.2977 70.1666
PF-382 GDSC1 -3.2635 -1.7177 -3.264 69.9551
LC4-1 GDSC1 -3.254 -0.9224 -3.2647 68.867
HH [Human lymphoma] GDSC1 -3.2534 -0.6604 -3.2736 68.4185
OPM-2 GDSC1 -3.2525 -1.7065 -3.253 69.8223
BV-173 GDSC1 -3.2303 -2.4446 -3.2303 69.825
KMS-11 GDSC1 -3.2034 -1.3295 -3.2059 68.9174
MOLT-4 GDSC1 -3.2011 -0.5882 -3.2231 67.8107
DB GDSC1 -3.1981 -1.8733 -3.1982 69.299
P12-Ichikawa GDSC1 -3.1877 -2.0072 -3.1877 69.229
KCL-22 GDSC1 -3.1217 -1.043 -3.1275 67.7147
ATN-1 GDSC1 -3.114 -1.7615 -3.1141 68.2524
MV4-11 GDSC1 -3.1137 -1.8426 -3.1138 68.2827
OCI-AML-2 GDSC1 -3.0984 -0.6207 -3.1161 66.8901
Mono-Mac-6 GDSC1 -3.0608 2.1477 -3.4999 61.9923
HC-1 GDSC1 -3.0538 -0.9243 -3.061 66.8601
MN-60 GDSC1 -3.049 0.4092 -3.1474 64.7286
SUP-T1 GDSC1 -3.0436 -1.6199 -3.0439 67.3535
A3/Kawakami GDSC1 -3.0335 -1.5054 -3.0341 67.1727
RPMI-8866 GDSC1 -3.0201 -0.9271 -3.0268 66.51
KG-1 GDSC1 -3.0184 -1.8375 -3.0184 67.1311
HL-60 GDSC1 -2.9861 -1.6923 -2.9862 66.6983
ARH-77 GDSC1 -2.9757 -1.0668 -2.9795 66.1796
P32/ISH GDSC1 -2.9756 -1.0221 -2.9801 66.1354
Loucy GDSC1 -2.9662 -1.4934 -2.9667 66.3796
KMOE-2 GDSC1 -2.9602 -1.1576 -2.9627 66.0878
THP-1 GDSC1 -2.9048 0.001 -2.9534 64.1061
EJM GDSC1 -2.8897 -0.3058 -2.9165 64.3924
OCI-AML-3 GDSC1 -2.8848 -1.3262 -2.8857 65.338
Sc-1 GDSC1 -2.8743 -1.0304 -2.8776 65.0215
DND-41 GDSC1 -2.8085 -1.8359 -2.8085 64.5487
LP-1 GDSC1 -2.7713 -0.6091 -2.782 63.5137
GR-ST GDSC1 -2.7424 1.3638 -2.9719 60.7247
Reh GDSC1 -2.7383 -1.2803 -2.739 63.5815
BALL-1 GDSC1 -2.7123 -0.9627 -2.715 63.1249
Ramos.2G6.4C10 GDSC1 -2.704 -1.6471 -2.704 63.2388
ME1 GDSC1 -2.6664 -1.0457 -2.6681 62.6311
EM-2 GDSC1 -2.6614 -0.5908 -2.6705 62.2893
JJN-3 GDSC1 -2.6585 -0.3218 -2.6774 62.0222
RL GDSC1 -2.6487 1.9099 -2.9907 59.2899
LAMA-84 GDSC1 -2.6357 -1.0559 -2.6371 62.2704
MOLT-16 GDSC1 -2.6332 -1.0784 -2.6344 62.2492
HT GDSC1 -2.6331 -0.3414 -2.6504 61.7671
SUP-HD1 GDSC1 -2.61 -0.8418 -2.6134 61.8687
MC116 GDSC1 -2.6043 -1.9924 -2.6043 62.0055
TUR GDSC1 -2.5968 -1.4737 -2.5968 61.8954
L-1236 GDSC1 -2.578 -0.7009 -2.5833 61.4192
TK [Human B-cell lymphoma] GDSC1 -2.4906 -0.269 -2.5072 60.1413
AMO1 GDSC1 -2.4817 0.1654 -2.5243 59.6882
BC-1 GDSC1 -2.4166 -1.131 -2.417 59.6324
RPMI-8226 GDSC1 -2.3937 -0.6976 -2.397 59.2515
BC-3 GDSC1 -2.3615 -1.2609 -2.3616 58.9627
NOMO-1 GDSC1 -2.3498 -1.0566 -2.3502 58.8001
ML-2 GDSC1 -2.3336 0.2377 -2.3754 58.0457
EB2 GDSC1 -2.3267 1.1454 -2.482 57.2462
K-562 GDSC1 -2.3139 -0.0168 -2.3376 57.9947
Karpas-299 GDSC1 -2.2675 -1.1243 -2.2677 57.787
Jiyoye GDSC1 -2.2424 -0.3074 -2.2519 57.3123
WSU-NHL GDSC1 -2.21 -0.3954 -2.2165 56.9571
Farage GDSC1 -2.181 -0.1602 -2.1941 56.5334
L-363 GDSC1 -2.1499 -0.0104 -2.1687 56.1117
PL-21 GDSC1 -2.1216 2.1399 -2.4732 54.6152
CTV-1 GDSC1 -2.1186 -0.7365 -2.1196 55.9118
Raji GDSC1 -2.0932 0.9735 -2.2038 55.0026
JURL-MK1 GDSC1 -2.0756 0.2117 -2.1047 55.1643
DEL GDSC1 -2.0089 -0.4459 -2.0119 54.5282
JVM-3 GDSC1 -1.9357 -0.4442 -1.9382 53.6276
Hs 445 GDSC1 -1.8927 0.3024 -1.9207 52.9977
U266B1 GDSC1 -1.7929 -0.3563 -1.7952 51.855
ROS-50 GDSC1 -1.6398 1.9853 -1.9093 49.9572
SCC-3 GDSC1 -1.5624 -0.5036 -1.5627 48.9824
MEG-01 GDSC1 -1.4118 1.5118 -1.56 47.3739
KY821 GDSC1 -1.0428 0.5814 -1.0576 42.5616
P31/FUJ GDSC1 -1.0073 0.1426 -1.009 42.0529
SK-MM-2 GDSC1 -0.7068 6.2858 -2.513 43.5086
DG-75 GDSC1 -0.09 3.6412 -0.7485 34.2974
RC-K8 GDSC1 0.0543 1.9139 -0.0505 29.4357
Granta-519 GDSC1 0.084 2.723 -0.2326 30.3832
SU-DHL-1 GDSC1 0.3316 1.1508 0.3284 25.327
U-698-M GDSC1 0.4011 5.5679 -1.0719 32.8968
Karpas-422 GDSC1 1.373 7.1968 -0.9255 27.4084
JVM-2 GDSC1 1.4115 7.0154 -0.801 26.6013
WSU-DLCL2 GDSC1 1.9361 6.2356 0.0561 19.2173
HDLM-2 GDSC1 2.2171 3.9848 1.4233 7.8762
KM-H2 GDSC1 3.7639 6.549 1.2843 4.5014
H9 GDSC1 3.785 5.5887 1.7181 1.6586
L-540 GDSC1 3.8919 6.6995 1.2915 4.1891
A4/Fukuda GDSC1 4.5671 14.525 -1.9985 21.4572
L-428 GDSC1 4.6859 6.6928 1.6881 0.8575
⏷ Show the Full List of 144 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC1 -3.5987 -1.0718 -3.6116 72.2726
ESO-26 GDSC1 -2.0095 -0.3204 -2.0148 54.519
KYAE-1 GDSC1 -1.5646 0.5613 -1.5977 49.0409
FLO-1 GDSC1 -1.5243 0.941 -1.5928 48.5877
OACM5.1 C GDSC1 -1.5164 1.6613 -1.7026 48.5951
ESO-51 GDSC1 -1.4171 1.4468 -1.5539 47.4187
SK-GT-4 GDSC1 -0.9098 2.349 -1.2061 42.0218
KYSE-220 GDSC1 -0.1028 2.103 -0.2627 31.7258
KYSE-50 GDSC1 0.9331 1.5923 0.9279 17.8209
HCE-4 GDSC1 4.5133 10.928 -0.2927 13.1405
TE-12 GDSC1 6.1555 8.8795 1.4682 0.7057
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 1.6596 9.7537 -1.938 30.5357
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-7 GDSC1 -4.9828 4.1168 -6.1947 67.9477
CHP-212 GDSC1 -4.1042 -2.3859 -4.1046 79.4795
SJNB-12 GDSC1 -3.921 -1.4477 -3.9295 75.7609
NH-12 GDSC1 -3.9138 -1.0747 -3.9338 74.7395
MHH-NB-11 GDSC1 -3.9101 -0.8061 -3.9432 73.9972
TGW GDSC1 -3.673 -1.3628 -3.6798 73.5308
SK-N-AS GDSC1 -3.5632 0.5548 -3.7161 68.2947
SJNB-13 GDSC1 -3.3556 -1.1651 -3.3621 70.2413
KP-N-YS GDSC1 -3.2865 -1.0665 -3.2941 69.4113
IMR-5 GDSC1 -3.12 -1.8245 -3.1202 68.3518
KP-N-YN GDSC1 -2.8345 -0.6684 -2.8446 64.2533
SJNB-6 GDSC1 -2.7169 -1.4151 -2.7171 63.3613
CHP-134 GDSC1 -2.5407 -0.5468 -2.5489 60.8965
Kelly GDSC1 -2.3809 -0.6946 -2.3841 59.0973
GI-ME-N GDSC1 -2.3803 1.6381 -2.636 57.3115
NB(TU)1 GDSC1 -2.2473 -0.0982 -2.2649 57.2798
SK-N-SH GDSC1 -2.2317 0.5707 -2.2997 56.7168
NB69 GDSC1 -2.1764 -1.114 -2.1765 56.6527
SK-N-MC-IXC GDSC1 -1.9066 -1.0701 -1.9066 53.2836
SJNB-10 GDSC1 -1.5198 1.1286 -1.6129 48.5581
SJNB-5 GDSC1 -0.817 1.2043 -0.8737 39.9635
GOTO GDSC1 -0.4709 4.7815 -1.6137 40.0771
SK-N-BE(2)-M17 GDSC1 -0.0091 4.0034 -0.8067 34.0702
SiMa GDSC1 0.3094 5.9562 -1.3427 34.5199
SK-N-FI GDSC1 0.3377 3.1616 -0.1092 28.1131
SK-N-DZ GDSC1 0.4132 5.2729 -0.9244 32.16
CHP-126 GDSC1 1.5633 5.6257 0.0213 21.0374
NB1 GDSC1 2.338 7.2873 -0.1246 18.8282
SJNB-14 GDSC1 2.4551 3.7788 1.7255 4.6266
LA-N-6 GDSC1 2.8615 9.321 -0.7146 20.4676
SJNB-17 GDSC1 3.7434 17.4118 -4.0491 30.1765
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 -0.1193 3.7063 -0.8049 34.7545
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-453 GDSC1 -4.0027 -2.3151 -4.0031 78.417
HCC1599 GDSC1 -3.1241 -1.9154 -3.1241 68.4329
Evsa-T GDSC1 -2.3467 -0.5591 -2.3517 58.6415
HCC202 GDSC1 -2.2087 0.9155 -2.319 56.2434
MDA-MB-361 GDSC1 -2.1234 -0.1668 -2.135 55.8557
T-47D GDSC1 -2.0932 0.1531 -2.1192 55.3895
OCUB-M GDSC1 -2.0553 -0.795 -2.0558 55.132
ZR-75-30 GDSC1 -1.9973 0.1546 -2.02 54.2688
CAL-148 GDSC1 -1.9832 0.0997 -2.0025 54.1166
DU4475 GDSC1 -1.9317 -0.0663 -1.9426 53.5333
HCC1428 GDSC1 -1.6761 0.1702 -1.6898 50.396
AU565 GDSC1 -1.505 0.9361 -1.5717 48.3568
MDA-MB-330 GDSC1 -1.5012 1.0842 -1.5867 48.3318
HCC1500 GDSC1 -1.4165 0.8335 -1.4667 47.2712
EFM-19 GDSC1 -1.0635 4.0352 -1.9387 44.9554
HCC1806 GDSC1 -0.8969 1.7027 -1.0393 41.3145
MFM-223 GDSC1 -0.8515 1.4398 -0.9435 40.5521
HCC1569 GDSC1 -0.7672 2.437 -1.0749 40.4338
HCC38 GDSC1 -0.7167 1.3301 -0.7831 38.7742
MDA-MB-231 GDSC1 -0.6351 2.7817 -1.0337 39.2806
HCC70 GDSC1 -0.4842 2.0894 -0.675 36.5675
HCC2218 GDSC1 -0.4412 3.1054 -0.9297 37.462
COLO 824 GDSC1 -0.3968 2.3308 -0.6413 35.7905
HCC1419 GDSC1 -0.3532 3.4005 -0.9396 36.9011
EFM-192A GDSC1 -0.2071 3.6708 -0.8847 35.689
UACC-812 GDSC1 -0.2013 2.5004 -0.4756 33.5952
MDA-MB-157 GDSC1 0.0915 1.803 0.0108 28.8193
HCC1937 GDSC1 0.4505 2.1625 0.326 24.6257
CAL-120 GDSC1 0.458 6.6931 -1.5436 34.4912
MDA-MB-175-VII GDSC1 0.488 3.7333 -0.1731 27.6542
HDQ-P1 GDSC1 0.7048 6.2266 -1.0829 31.3447
BT-474 GDSC1 0.7705 5.7745 -0.8046 29.6805
BT-20 GDSC1 1.0138 3.2069 0.5952 19.652
HCC2157 GDSC1 1.1486 4.7523 0.0467 22.7936
JIMT-1 GDSC1 1.1808 3.9476 0.4501 19.8424
CAMA-1 GDSC1 1.2837 8.6826 -1.74 31.3481
Hs 578T GDSC1 1.2986 2.6878 1.097 14.5791
BT-549 GDSC1 1.3204 3.521 0.7825 16.743
MRK-nu-1 GDSC1 1.3821 7.6364 -1.134 28.3747
HCC1187 GDSC1 1.4232 5.3885 0.0063 21.7673
MDA-MB-468 GDSC1 1.626 5.013 0.3791 18.2831
CAL-85-1 GDSC1 1.7378 11.0925 -2.5375 32.238
UACC-893 GDSC1 1.8175 5.5142 0.3085 17.9644
MDA-MB-436 GDSC1 1.889 6.6835 -0.2082 21.1315
HCC1954 GDSC1 2.0283 6.3677 0.071 18.7432
YMB-1-E GDSC1 2.2324 7.5534 -0.3464 20.6173
MCF-7 GDSC1 3.0354 5.9921 1.0685 7.9174
CAL-51 GDSC1 3.3294 6.697 0.9336 8.0914
HCC1395 GDSC1 3.4819 7.7904 0.5105 10.7177
MDA-MB-415 GDSC1 3.5442 7.8611 0.5199 10.476
BT-483 GDSC1 5.13 6.6798 1.8604 0.171
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GB-1 GDSC1 -3.66 -1.0805 -3.6738 72.8033
Daoy GDSC1 -3.3568 -1.876 -3.3571 71.1351
U-251MG GDSC1 -2.7831 -0.1149 -2.8178 63.0839
GI-1 GDSC1 -2.1533 -0.2321 -2.1633 56.2307
SF268 GDSC1 -2.0922 0.5585 -2.1512 55.2034
GaMG GDSC1 -2.0469 -0.1564 -2.0571 54.9389
MOG-G-UVW GDSC1 -1.8457 0.3819 -1.8773 52.4261
AM-38 GDSC1 -1.6513 2.4496 -2.0432 50.0734
KINGS-1 GDSC1 -1.6451 0.5268 -1.679 50.0147
D-423MG GDSC1 -1.561 0.9994 -1.6392 49.0297
ONS-76 GDSC1 -1.4047 1.6781 -1.5849 47.3382
YKG-1 GDSC1 -1.3143 1.4645 -1.446 46.2181
8-MG-BA GDSC1 -1.2933 2.6172 -1.7008 46.4596
SF539 GDSC1 -1.2806 1.7865 -1.473 45.9537
MOG-G-CCM GDSC1 -1.1386 1.9954 -1.3657 44.4184
D-566MG GDSC1 -1.0608 1.1588 -1.1272 42.9992
H4 GDSC1 -0.9402 0.372 -0.9449 41.2309
SF295 GDSC1 -0.8984 0.3748 -0.9026 40.7057
D-542MG GDSC1 -0.8539 1.401 -0.9401 40.5556
D-247MG GDSC1 -0.7827 1.191 -0.8357 39.5219
KNS-81-FD GDSC1 -0.6376 1.5668 -0.7343 37.9559
SF126 GDSC1 -0.636 1.3749 -0.7031 37.7809
D-336MG GDSC1 -0.494 1.2026 -0.5315 35.8519
M059J GDSC1 -0.4863 2.6456 -0.8295 37.3326
A-172 GDSC1 -0.4331 0.6107 -0.4358 34.8821
D-502MG GDSC1 -0.2122 1.9326 -0.3435 32.9058
PFSK-1 GDSC1 -0.1783 1.5782 -0.2428 32.0808
NMC-G1 GDSC1 -0.1299 3.6746 -0.8038 34.8168
SW1783 GDSC1 -0.1169 1.4661 -0.162 31.1951
KALS-1 GDSC1 -0.1106 3.1115 -0.5744 33.5449
KNS-42 GDSC1 -0.0638 2.9198 -0.4577 32.6129
D-392MG GDSC1 -0.0608 2.4973 -0.3214 31.8118
LN-229 GDSC1 -0.0195 3.8231 -0.745 33.8368
LNZTA3WT4 GDSC1 0.022 2.7264 -0.3011 31.1747
CAS-1 GDSC1 0.0349 2.104 -0.113 29.9479
T98G GDSC1 0.0466 1.7835 -0.0342 29.3801
42-MG-BA GDSC1 0.0522 2.4434 -0.1826 30.2736
KS-1 [Human Krukenberg tumour] GDSC1 0.0576 4.1231 -0.7858 33.5606
Hs 683 GDSC1 0.2292 2.2263 0.0691 27.6135
DBTRG-05MG GDSC1 0.5271 3.6744 -0.1078 27.0283
D-263MG GDSC1 0.5284 1.4502 0.5178 22.9131
LN-405 GDSC1 0.5465 3.6813 -0.0903 26.8097
SK-MG-1 GDSC1 0.5914 3.1674 0.1607 24.925
LN-18 GDSC1 0.6102 1.8418 0.5625 22.129
Onda 10 GDSC1 0.6346 3.0569 0.2483 24.0975
YH-13 GDSC1 0.6531 3.0394 0.2746 23.8178
U-87MG ATCC GDSC1 0.7005 4.1387 -0.1245 26.1875
U-118MG GDSC1 0.7821 3.7845 0.1127 24.2121
DK-MG GDSC1 0.8533 4.0137 0.087 24.01
SNB-75 GDSC1 1.5063 4.8518 0.3446 19.0631
Onda 11 GDSC1 2.0615 5.9068 0.3297 16.8157
SW1088 GDSC1 2.1966 5.2996 0.7495 13.1929
D283 Med GDSC1 4.2187 5.5104 1.9364 0.3028
Becker GDSC1 4.9541 6.3442 1.9124 0.1291
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 -1.1994 1.0551 -1.2616 44.6715
ETK-1 GDSC1 -0.6241 3.8135 -1.3847 40.4319
TGBC1TKB GDSC1 0.4203 2.7822 0.1135 26.204
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC1 -1.927 -0.032 -1.9389 53.4698
ESS-1 GDSC1 -1.2685 0.7608 -1.3043 45.4333
EN GDSC1 -0.426 4.1739 -1.3156 38.8433
MFE-280 GDSC1 -0.1252 7.1203 -2.3146 39.8447
KLE GDSC1 0.2304 4.0616 -0.5793 31.4767
AN3-CA GDSC1 0.44 3.65 -0.1896 28.0256
MFE-296 GDSC1 2.2747 4.9319 0.9997 10.9746
MFE-319 GDSC1 2.5715 5.1044 1.1571 8.6936
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-21 GDSC1 -2.3876 1.2281 -2.5622 57.7537
KTCTL-1M GDSC1 -2.1625 1.6431 -2.4004 55.2984
769-P GDSC1 -2.0835 0.4037 -2.1275 55.1768
KTCTL-140 GDSC1 -2.0697 0.7862 -2.1533 54.8469
NCC021 GDSC1 -1.7839 0.1015 -1.7976 51.7179
LB1047-RCC GDSC1 -1.6818 0.2749 -1.7007 50.4637
Caki-1 GDSC1 -1.6183 1.3717 -1.7577 49.7131
RXF 393L GDSC1 -1.1081 1.4689 -1.2244 43.7447
CAL-54 GDSC1 -0.9993 0.3347 -1.0041 41.9698
786-O GDSC1 -0.9518 2.5683 -1.314 42.6974
BB65-RCC GDSC1 -0.8997 1.4739 -1.0008 41.1785
VMRC-RCZ GDSC1 -0.7596 0.9227 -0.7853 39.0921
KMRC-1 GDSC1 -0.6306 0.8129 -0.6444 37.4167
KTCTL-26A GDSC1 -0.6109 0.9119 -0.6298 37.2013
KTCTL-195 GDSC1 -0.6035 3.1463 -1.1195 39.3791
VMRC-RCW GDSC1 -0.088 2.5152 -0.3563 32.1873
ACHN GDSC1 0.0042 2.8876 -0.3731 31.706
OS-RC-2 GDSC1 0.0921 4.3521 -0.8458 33.6385
UO-31 GDSC1 0.3667 1.7963 0.3082 25.2413
SN12C GDSC1 0.5489 3.0613 0.1547 25.2023
LB996-RCC GDSC1 0.5752 2.6037 0.3397 23.8131
BFTC-909 GDSC1 0.6402 2.5235 0.4352 22.8001
KTCTL-13 GDSC1 0.9557 4.0554 0.1734 22.9013
LB2241-RCC GDSC1 1.0026 3.0835 0.6319 19.4507
RCC10RGB GDSC1 1.1405 5.2602 -0.2015 24.4328
KMRC-20 GDSC1 1.856 3.2356 1.4524 9.1724
SW156 GDSC1 2.314 6.4741 0.262 16.318
A-498 GDSC1 2.3463 4.6281 1.212 9.0532
SW13 GDSC1 3.6173 5.6466 1.605 2.624
HA7-RCC GDSC1 4.1802 6.736 1.4346 2.7493
TK-10 GDSC1 4.5968 8.3642 0.95 5.0801
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-61 GDSC1 -3.3465 -0.6849 -3.3682 69.3018
LS411N GDSC1 -2.9807 -1.2194 -2.9828 66.3683
SW837 GDSC1 -2.6202 -0.5465 -2.6298 61.7952
HCT 116 GDSC1 -2.6028 -0.5588 -2.6117 61.6083
SNU-175 GDSC1 -2.2815 -1.2192 -2.2816 57.965
CCK-81 GDSC1 -2.2351 -1.0333 -2.2354 57.3787
HT-29 GDSC1 -1.731 0.2802 -1.7519 51.0626
SW620 GDSC1 -1.7221 -0.0923 -1.7282 50.9696
SW1116 GDSC1 -1.7016 1.3613 -1.8456 50.6438
COLO 320HSR GDSC1 -1.6387 2.0423 -1.922 49.9462
SNU-C2B GDSC1 -1.484 1.1423 -1.5765 48.1381
COLO205 GDSC1 -1.424 1.2942 -1.5354 47.4614
LS1034 GDSC1 -1.2914 0.4504 -1.3072 45.6531
SW626 GDSC1 -1.1641 0.6027 -1.1841 44.0907
HT115 GDSC1 -1.1013 0.3342 -1.1078 43.2511
RKO GDSC1 -1.0935 1.6646 -1.2448 43.6819
SW948 GDSC1 -1.0862 3.3305 -1.7056 44.7208
SW1417 GDSC1 -0.9336 0.8858 -0.9642 41.2796
RCM-1 [Human ESC] GDSC1 -0.9216 0.4773 -0.9289 41.0128
C2BBe1 GDSC1 -0.8351 1.3629 -0.9143 40.2937
SNU-407 GDSC1 -0.7865 3.5903 -1.4751 41.8729
SW48 GDSC1 -0.76 1.7723 -0.9048 39.6788
GP5d GDSC1 -0.7469 0.9697 -0.7758 38.9515
CW-2 GDSC1 -0.6203 3.4082 -1.2299 39.8963
LS123 GDSC1 -0.6102 1.1498 -0.6487 37.3039
NCI-H747 GDSC1 -0.3881 1.6991 -0.4884 34.8995
CaR-1 GDSC1 -0.3466 3.1036 -0.8267 36.3521
T84 GDSC1 -0.3277 1.8134 -0.4444 34.2473
LS180 GDSC1 -0.2405 2.7919 -0.6076 34.5637
MDST8 GDSC1 -0.1946 0.1939 -0.1946 31.8847
SNU-C1 GDSC1 -0.1694 3.5977 -0.8164 35.1305
SNU-C5 GDSC1 -0.1583 3.6562 -0.8271 35.1088
KM12 GDSC1 -0.1493 4.0982 -0.993 35.7932
HCC2998 GDSC1 -0.1238 1.5311 -0.1778 31.3371
HT-55 GDSC1 -0.0849 1.1396 -0.0987 30.5992
LS513 GDSC1 0.1706 4.4193 -0.7929 32.9173
HCT 15 GDSC1 0.2922 2.6973 0.0021 27.6717
NCI-H716 GDSC1 0.4547 3.9352 -0.2919 28.5623
SW1463 GDSC1 0.4592 1.5545 0.4375 23.8493
LoVo GDSC1 0.811 4.3281 -0.0955 25.4197
COLO 678 GDSC1 1.4026 3.9401 0.6761 17.1301
CL-11 GDSC1 3.3321 8.8897 -0.1372 15.5038
SNU-1040 GDSC1 4.1923 5.4984 1.9307 0.331
SNU-81 GDSC1 4.3867 6.1485 1.7691 0.7664
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 -2.6373 0.797 -2.7604 60.539
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC1 -3.6557 -3.0042 -3.6557 75.1436
JHH-4 GDSC1 -2.9435 0.304 -3.0232 63.9943
SNU-387 GDSC1 -1.9948 -0.2458 -2.0015 54.3271
SNU-423 GDSC1 -1.646 0.3912 -1.6704 50.0255
Huh-7 GDSC1 -1.2994 0.7742 -1.3379 45.8195
Hep 3B2.1-7 GDSC1 -0.9932 0.6391 -1.0094 41.9505
SNU-475 GDSC1 -0.8656 2.1267 -1.1 41.2975
JHH-2 GDSC1 -0.8498 0.9791 -0.8845 40.2606
SNU-398 GDSC1 -0.5251 3.3537 -1.1077 38.7737
JHH-7 GDSC1 -0.3268 1.2739 -0.3626 33.7569
SK-HEP-1 GDSC1 -0.2696 2.2577 -0.4831 34.0845
HLE GDSC1 -0.0543 1.6808 -0.1256 30.578
Hep-G2/C3A GDSC1 0.4278 1.501 0.4093 24.2215
JHH-6 GDSC1 0.6143 3.5633 0.0294 25.6662
HuH-1 GDSC1 1.0671 2.6314 0.8656 17.46
SNU-449 GDSC1 1.4913 7.2538 -0.8461 26.4822
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2731 GDSC1 -5.0834 -2.1338 -5.0938 84.5684
COR-L321 GDSC1 -4.2497 -2.9575 -4.2497 81.9167
COR-L303 GDSC1 -4.1366 -2.5755 -4.1367 80.1544
SBC-3 GDSC1 -3.9914 0.9505 -4.2442 69.9531
NCI-H847 GDSC1 -3.9801 -2.5777 -3.9801 78.6351
NCI-H748 GDSC1 -3.9687 -1.8677 -3.9713 77.1648
IST-SL1 GDSC1 -3.9516 -2.2442 -3.9521 77.807
NCI-H510A GDSC1 -3.7984 -0.896 -3.8232 73.4383
NCI-H211 GDSC1 -3.7553 -1.8471 -3.7568 75.2337
NCI-H810 GDSC1 -3.6927 -2.2318 -3.6929 75.1813
NCI-H2227 GDSC1 -3.677 -2.1413 -3.6773 74.9071
Ms-1 GDSC1 -3.1473 -1.2274 -3.1505 68.2031
UMC-11 GDSC1 -3.0848 -1.9636 -3.0848 67.9695
Lu-139 GDSC1 -2.8356 -0.4913 -2.8519 64.0728
NCI-H446 GDSC1 -2.8117 -0.5601 -2.8249 63.8974
HCC33 GDSC1 -2.7794 -1.3951 -2.7798 64.1136
DMS 273 GDSC1 -2.7335 0.5724 -2.8324 61.7103
NCI-H1755 GDSC1 -2.611 -0.655 -2.6177 61.7684
NCI-H292 GDSC1 -2.5572 1.1663 -2.7342 59.3754
LC-2/ad GDSC1 -2.4367 0.2219 -2.4819 59.1635
NCI-H1581 GDSC1 -2.4018 -1.2136 -2.402 59.4587
NCI-H196 GDSC1 -2.3899 -0.5223 -2.3963 59.1373
SBC-5 GDSC1 -2.3842 -0.7981 -2.3862 59.1688
HCC44 GDSC1 -2.3513 0.0247 -2.3788 58.3869
NCI-H1694 GDSC1 -2.3438 -0.5507 -2.349 58.6047
CPC-N GDSC1 -2.3132 -1.144 -2.3134 58.3555
NCI-H2135 GDSC1 -2.3071 0.2568 -2.3492 57.7432
NCI-H187 GDSC1 -2.2722 -0.9258 -2.2729 57.8275
NCI-H526 GDSC1 -2.1639 -0.1987 -2.1753 56.3456
EPLC-272H GDSC1 -2.1479 1.7063 -2.3983 55.1201
NCI-H661 GDSC1 -2.0576 -0.9401 -2.0578 55.1678
NCI-H1693 GDSC1 -2.0204 3.4646 -2.763 53.1251
NCI-H64 GDSC1 -2.0181 -1.574 -2.0181 54.6774
NCI-H1944 GDSC1 -1.9868 0.0327 -2.0029 54.175
NCI-H345 GDSC1 -1.9404 0.5547 -1.9909 53.4921
NCI-H1092 GDSC1 -1.9239 0.2977 -1.9528 53.3678
NCI-H1648 GDSC1 -1.9128 0.5132 -1.9581 53.185
Lu-165 GDSC1 -1.8859 1.3362 -2.04 52.6528
Lu-134-A GDSC1 -1.8549 -0.2664 -1.8592 52.617
NCI-H2171 GDSC1 -1.8492 -0.791 -1.8494 52.5655
PC-14 GDSC1 -1.8202 0.352 -1.8487 52.1284
NCI-H2196 GDSC1 -1.7453 0.1264 -1.759 51.2451
SBC-1 GDSC1 -1.6892 -0.3314 -1.6909 50.5647
Calu-6 GDSC1 -1.6586 0.5079 -1.6916 50.1778
NCI-H1770 GDSC1 -1.6102 -0.5648 -1.6104 49.5797
Lu-135 GDSC1 -1.5543 -0.3516 -1.5552 48.8824
NCI-H358 GDSC1 -1.5369 1.2034 -1.6423 48.7667
HCC78 GDSC1 -1.5031 0.6108 -1.5373 48.2945
NCI-H226 GDSC1 -1.4849 0.1033 -1.492 48.0286
NCI-H2110 GDSC1 -1.4782 2.0396 -1.7464 48.2445
NCI-H1155 GDSC1 -1.4738 -0.2041 -1.4753 47.8785
NCI-H2029 GDSC1 -1.4164 1.3428 -1.5352 47.3842
HOP-62 GDSC1 -1.372 1.5895 -1.5317 46.936
NCI-H522 GDSC1 -1.3382 2.2383 -1.644 46.7844
EMC-BAC-2 GDSC1 -1.3282 1.1017 -1.4045 46.263
COLO 668 GDSC1 -1.316 1.7672 -1.5073 46.3536
COR-L105 GDSC1 -1.3126 2.1766 -1.6001 46.4802
LCLC-97TM1 GDSC1 -1.2366 1.6255 -1.3922 45.3674
NCI-H3122 GDSC1 -1.2365 2.2159 -1.5272 45.6547
LK-2 GDSC1 -1.231 1.4813 -1.3592 45.2352
NCI-H1436 GDSC1 -1.1662 0.4684 -1.1792 44.0885
NCI-H1975 GDSC1 -1.1469 1.6683 -1.3034 44.3241
NCI-H1623 GDSC1 -1.1396 1.5019 -1.2642 44.1455
ABC-1 GDSC1 -1.1342 3.5034 -1.8181 45.3044
NCI-H2347 GDSC1 -1.1164 3.199 -1.6931 44.9407
NCI-H2803 GDSC1 -1.0655 0.4775 -1.0762 42.8247
NCI-H1651 GDSC1 -1.0566 1.4189 -1.1606 43.0863
NCI-H647 GDSC1 -1.0534 1.6153 -1.1918 43.1663
PaCa-3 GDSC1 -0.9655 3.7143 -1.713 43.7933
LC-1/sq GDSC1 -0.8679 2.7544 -1.2787 41.9208
NCI-H1915 GDSC1 -0.8497 3.3469 -1.4556 42.294
SW1271 GDSC1 -0.8135 1.9338 -0.9974 40.4874
NCI-H1573 GDSC1 -0.8117 1.521 -0.914 40.1135
NCI-H2373 GDSC1 -0.8005 1.1512 -0.8499 39.7238
NCI-H520 GDSC1 -0.7903 2.9965 -1.2717 41.2972
NCI-H1734 GDSC1 -0.7853 1.3168 -0.8545 39.634
NCI-H1876 GDSC1 -0.778 1.983 -0.97 40.0993
SHP-77 GDSC1 -0.7268 2.6036 -1.0791 40.1409
COR-L23 GDSC1 -0.7143 3.4729 -1.3546 40.9884
NCI-H1437 GDSC1 -0.6964 3.0967 -1.2032 40.3612
LCLC-103H GDSC1 -0.6844 1.1336 -0.7253 38.24
NCI-H2722 GDSC1 -0.6643 1.4813 -0.7491 38.2232
LXF 289 GDSC1 -0.6538 1.7608 -0.7874 38.3392
NCI-H23 GDSC1 -0.6386 1.4001 -0.7094 37.8324
NCI-H2087 GDSC1 -0.5806 2.0454 -0.7696 37.7223
NCI-H2595 GDSC1 -0.5534 1.6169 -0.6522 36.9313
RERF-LC-MS GDSC1 -0.5403 2.9286 -0.9778 38.3648
COR-L95 GDSC1 -0.5393 1.9006 -0.692 37.0411
NCI-H2141 GDSC1 -0.4821 1.7141 -0.5926 36.1163
NCI-H650 GDSC1 -0.4781 2.7761 -0.861 37.4181
NCI-H1836 GDSC1 -0.4297 0.6561 -0.4332 34.8448
BEN GDSC1 -0.3544 2.6348 -0.6825 35.7112
SK-MES-1 GDSC1 -0.3336 2.5657 -0.6391 35.3491
NCI-H838 GDSC1 -0.3158 2.2804 -0.5395 34.7018
Lu-65 GDSC1 -0.2699 2.5853 -0.5755 34.59
NCI-H1666 GDSC1 -0.2555 2.0867 -0.4252 33.6639
HARA [Human squamous cell lung carcinoma] GDSC1 -0.2506 3.1798 -0.7497 35.3445
NCI-H596 GDSC1 -0.2425 2.5899 -0.547 34.2561
NCI-H2869 GDSC1 -0.2217 1.8391 -0.3347 32.9141
HCC827 GDSC1 -0.2148 1.9316 -0.3462 32.9386
NCI-H524 GDSC1 -0.1928 0.9846 -0.2019 31.9187
NCI-H2444 GDSC1 -0.1785 4.6756 -1.2647 37.0638
LOU-NH91 GDSC1 -0.1671 0.8023 -0.17 31.5587
NCI-H1048 GDSC1 -0.132 2.9205 -0.5319 33.4552
EBC-1 GDSC1 -0.1251 3.7438 -0.8258 34.8899
NCI-H2804 GDSC1 -0.0863 3.0409 -0.5235 33.1172
CAL-12T GDSC1 -0.0695 5.2054 -1.3828 36.8299
NCI-H2030 GDSC1 0.0071 3.2249 -0.4879 32.3349
DMS 79 GDSC1 0.0403 2.1151 -0.1097 29.8936
NCI-H1869 GDSC1 0.1 2.8091 -0.2431 30.3495
NCI-H2405 GDSC1 0.112 3.3838 -0.4342 31.3905
NCI-H841 GDSC1 0.1766 1.7318 0.1143 27.6397
NCI-H2461 GDSC1 0.1978 3.7126 -0.4709 31.0799
NCI-H1435 GDSC1 0.2181 1.6605 0.1694 27.0347
RERF-LC-Sq1 GDSC1 0.2791 2.1847 0.1338 26.8973
EMC-BAC-1 GDSC1 0.3325 6.2764 -1.4693 34.8762
NCI-H2369 GDSC1 0.3579 1.8791 0.2846 25.447
NCI-H2172 GDSC1 0.3758 3.4528 -0.1792 28.328
NCI-H2795 GDSC1 0.3824 1.4175 0.3684 24.7599
NCI-H1993 GDSC1 0.432 4.6549 -0.6269 30.5732
NCI-H322M GDSC1 0.4971 3.6013 -0.1096 27.2067
NCI-H82 GDSC1 0.6005 3.4849 0.0465 25.6306
NCI-H2170 GDSC1 0.6815 3.7762 0.0116 25.4174
SW1573 GDSC1 0.7517 2.8231 0.4587 22.0153
ChaGo-K-1 GDSC1 0.7561 3.7597 0.0962 24.4602
A-549 GDSC1 0.7926 2.8018 0.5102 21.4348
NCI-H2081 GDSC1 0.7947 5.111 -0.4696 27.7604
HOP-92 GDSC1 0.8299 3.7495 0.1774 23.5252
NCI-H1688 GDSC1 0.8713 1.4232 0.87 18.5688
NCI-H2023 GDSC1 0.915 3.6721 0.2987 22.2504
DMS 114 GDSC1 0.9469 3.6629 0.3357 21.8283
NCI-H441 GDSC1 1.0931 4.2311 0.2331 21.8012
Calu-3 GDSC1 1.1555 6.7839 -0.9236 28.3931
IA-LM GDSC1 1.2297 4.5523 0.2201 21.2251
NCI-H2818 GDSC1 1.2381 7.2985 -1.0991 28.8566
NCI-H1650 GDSC1 1.2419 5.8934 -0.4094 25.2085
NCI-H2122 GDSC1 1.2932 4.8504 0.1412 21.465
SK-LU-1 GDSC1 1.3259 3.3158 0.8772 16.021
NCI-H2085 GDSC1 1.3696 5.7577 -0.2235 23.4895
Lu-99A GDSC1 1.3877 6.0981 -0.3726 24.3155
NCI-H1781 GDSC1 1.452 4.4708 0.4754 18.3706
NCI-H727 GDSC1 1.6275 7.3547 -0.7736 25.5125
NCI-H1299 GDSC1 1.6304 4.7612 0.5057 17.3459
NCI-H1563 GDSC1 1.644 6.7485 -0.4585 23.6854
NCI-H3255 GDSC1 1.7381 4.7331 0.6201 16.0313
NCI-H1792 GDSC1 1.7475 4.0312 0.9696 13.3485
NCI-H1793 GDSC1 1.8212 4.2494 0.9336 13.3035
NCI-H1703 GDSC1 1.8258 5.121 0.5102 16.4715
NCI-H2591 GDSC1 2.0541 7.5107 -0.4769 22.0938
NCI-H1963 GDSC1 2.0767 6.4374 0.0783 18.5009
NCI-H1304 GDSC1 2.3646 6.7528 0.1649 16.802
EKVX GDSC1 2.3968 8.5527 -0.7083 22.09
A-427 GDSC1 2.3982 6.6907 0.2238 16.2704
NCI-H2228 GDSC1 2.5067 8.2681 -0.4753 20.3588
LB647-SCLC GDSC1 2.7576 5.6622 1.0246 9.1057
NCI-H2009 GDSC1 2.7749 6.6754 0.5348 12.7253
DMS 53 GDSC1 2.9812 7.2959 0.3859 13.1151
NCI-H2342 GDSC1 3.0115 8.4723 -0.1744 16.7663
RERF-LC-KJ GDSC1 3.2165 6.9855 0.7134 10.0305
NCI-H460 GDSC1 3.2839 6.1558 1.1628 6.5169
HCC15 GDSC1 3.4624 7.3454 0.7125 9.3349
COR-L88 GDSC1 3.565 23.8441 -7.3978 36.4493
NCI-H1355 GDSC1 3.7217 9.1141 0.0366 13.233
NCI-H1838 GDSC1 4.0351 8.827 0.3903 10.0534
NCI-H720 GDSC1 4.3837 11.4109 -0.6131 15.3119
NCI-H513 GDSC1 4.426 7.4979 1.2364 3.5697
NCI-H2291 GDSC1 4.4428 6.4954 1.6599 1.1882
NCI-H1568 GDSC1 4.5895 6.5 1.7207 0.8026
NCI-H209 GDSC1 4.894 6.6811 1.7746 0.4391
IST-SL2 GDSC1 5.0779 7.1625 1.672 0.6547
NCI-H69 GDSC1 5.5994 18.5513 -3.2235 23.3567
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 -1.0315 0.5212 -1.0431 42.4055
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-180 GDSC1 -1.6717 1.2073 -1.7875 50.3162
OE33 GDSC1 -1.5675 1.6668 -1.7592 49.1635
TE-15 GDSC1 -1.2729 1.9089 -1.4918 45.9188
KYSE-450 GDSC1 -0.453 1.3089 -0.4999 35.3958
TE-4 GDSC1 -0.4261 2.5541 -0.7365 36.471
KYSE-70 GDSC1 0.0269 3.018 -0.3931 31.6803
KYSE-510 GDSC1 0.2249 2.6664 -0.0613 28.4738
KYSE-270 GDSC1 0.3758 2.9785 -0.0021 27.2123
T.T GDSC1 0.5061 3.3344 0.0057 26.4202
OE21 GDSC1 0.5424 3.2565 0.0744 25.7691
KYSE-410 GDSC1 0.838 4.0643 0.0492 24.3402
OE19 GDSC1 0.8429 2.9375 0.5161 21.1185
KYSE-520 GDSC1 0.9607 5.7879 -0.6267 27.7927
TE-10 GDSC1 1.7367 7.212 -0.6055 24.1312
EC-GI-10 GDSC1 1.8855 4.3273 0.9552 12.8641
KYSE-150 GDSC1 2.0224 6.1869 0.156 18.1882
TE-11 GDSC1 3.6251 8.5886 0.2237 12.2783
TE-1 GDSC1 4.04 8.5289 0.535 9.0645
TE-9 GDSC1 4.0593 5.5435 1.8613 0.6526
TE-5 GDSC1 4.5829 10.0926 0.1489 10.2759
COLO 680N GDSC1 4.7074 6.5691 1.7428 0.6406
TE-8 GDSC1 4.9762 7.1394 1.6399 0.8308
TE-6 GDSC1 5.2694 6.9574 1.815 0.2141
KYSE-140 GDSC1 5.5561 7.7263 1.6523 0.4743
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVCAR-8 GDSC1 -3.3226 -0.394 -3.3597 68.5274
ES-2 GDSC1 -3.0573 -0.5453 -3.0772 66.3776
OAW28 GDSC1 -2.2604 0.6404 -2.3381 56.9737
OVCAR-5 GDSC1 -1.8846 1.0918 -1.9981 52.7099
A2780 GDSC1 -1.5886 0.1408 -1.599 49.318
IGROV-1 GDSC1 -1.5856 1.808 -1.8092 49.3731
SK-OV-3 GDSC1 -1.3572 0.5222 -1.3792 46.4839
TOV-112D GDSC1 -1.3318 0.0832 -1.336 46.1157
TYK-nu GDSC1 -1.1417 2.3592 -1.462 44.6784
EFO-27 GDSC1 -1.0594 4.432 -2.0892 45.1597
OC 314 GDSC1 -0.9689 0.7839 -0.9932 41.6875
OV-90 GDSC1 -0.8439 2.113 -1.0729 41.024
Kuramochi GDSC1 -0.607 2.0516 -0.7998 38.0589
RMG-I GDSC1 -0.5553 1.7404 -0.6768 37.0746
OV56 GDSC1 -0.4975 1.9239 -0.6516 36.5389
OVKATE GDSC1 -0.2083 3.881 -0.9682 36.0651
OVISE GDSC1 -0.0357 1.0132 -0.0421 29.9383
JHOS-2 GDSC1 0.0587 4.7024 -1.0306 34.6729
OVTOKO GDSC1 0.0936 3.8646 -0.6421 32.6237
OAW42 GDSC1 0.2786 1.7072 0.2274 26.2953
TOV-21G GDSC1 1.3477 3.4955 0.8217 16.3207
Caov-3 GDSC1 1.4131 4.1101 0.6076 17.5854
OVCAR-4 GDSC1 1.4494 4.5446 0.4377 18.6546
EFO-21 GDSC1 1.8739 5.8589 0.1883 18.5713
FU-OV-1 GDSC1 2.1875 4.289 1.2459 9.3835
OVK18 GDSC1 4.2466 6.5044 1.5653 1.8932
DOV13 GDSC1 4.5622 6.2616 1.7981 0.5424
OVCAR-3 GDSC1 4.5852 6.2285 1.819 0.4629
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PSN1 GDSC1 -3.2529 -0.3761 -3.2885 67.8932
QGP-1 GDSC1 -1.979 3.0958 -2.5958 52.9267
MZ-PC-1 GDSC1 -1.7539 3.5534 -2.5051 50.9345
SUIT-2 GDSC1 -1.6093 0.3177 -1.6282 49.5768
Panc 02.03 GDSC1 -1.2754 0.96 -1.3312 45.5752
KP-2 GDSC1 -1.1775 1.6983 -1.3426 44.7046
PaTu 8902 GDSC1 -1.1222 0.842 -1.158 43.6347
HuP-T4 GDSC1 -1.0358 1.428 -1.1398 42.8359
Panc 10.05 GDSC1 -1.017 2.0491 -1.2459 43.0315
DAN-G GDSC1 -0.6857 0.7138 -0.6964 38.0868
KP-4 GDSC1 -0.6552 3.5121 -1.3052 40.4014
HPAC GDSC1 -0.6169 2.3137 -0.8769 38.4871
HuP-T3 GDSC1 -0.3853 3.4039 -0.9754 37.2717
BxPC-3 GDSC1 -0.3307 1.8294 -0.4509 34.3044
KP-3 GDSC1 -0.2372 2.3745 -0.4791 33.8495
AsPC-1 GDSC1 0.123 5.2518 -1.2076 35.032
Panc 03.27 GDSC1 0.1535 2.8898 -0.212 29.8375
Capan-1 GDSC1 0.278 2.4204 0.0704 27.3151
MIA PaCa-2 GDSC1 0.4671 2.097 0.3592 24.3095
PL4 GDSC1 0.8025 4.7611 -0.3004 26.7318
Panc 08.13 GDSC1 0.9766 3.8286 0.2948 21.9601
PaTu 8988t GDSC1 1.072 3.296 0.6203 19.1706
SU.86.86 GDSC1 1.0802 2.2834 0.9829 16.5847
Hs 766T GDSC1 1.0996 4.5645 0.0862 22.7691
HPAF-II GDSC1 1.7171 5.5095 0.2197 19.0148
YAPC GDSC1 2.7919 6.9961 0.3886 13.7205
Capan-2 GDSC1 3.1321 8.3853 -0.0387 15.5053
Panc 04.03 GDSC1 3.5456 9.4132 -0.2368 15.4722
SW1990 GDSC1 4.1527 8.8429 0.46 9.2926
CFPAC-1 GDSC1 4.9213 11.9961 -0.5303 13.4934
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 -3.8434 -0.6264 -3.8853 73.0638
MSTO-211H GDSC1 -0.6785 1.3722 -0.7481 38.319
IST-Mes1 GDSC1 -0.3337 1.2244 -0.3649 33.815
NCI-H28 GDSC1 3.5549 7.9858 0.467 10.8155
NCI-H2052 GDSC1 4.3278 10.7307 -0.3237 13.8013
NCI-H2452 GDSC1 4.643 6.9611 1.5662 1.4283
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1 -3.5422 -0.7649 -3.5658 71.1339
LNCaP clone FGC GDSC1 -3.316 -0.9365 -3.3274 69.4812
22Rv1 GDSC1 -2.6732 -0.1209 -2.7034 61.9726
DU145 GDSC1 -1.6047 0.615 -1.644 49.5285
PC-3 GDSC1 -0.2602 5.7086 -1.8011 39.2985
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 1.802 3.943 1.0641 12.3861
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MZ-MEL-7 GDSC1 -2.8919 -0.3725 -2.9152 64.5022
CHL-1 GDSC1 -2.431 1.0991 -2.5865 58.2847
IPC-298 GDSC1 -2.3907 0.1101 -2.4253 58.7595
A-431 GDSC1 -2.2709 -0.24 -2.2832 57.6187
G-361 GDSC1 -2.231 -0.1594 -2.2454 57.1178
VMRC-MELG GDSC1 -2.0531 0.3119 -2.0883 54.8667
IGR-37 GDSC1 -1.9128 1.1139 -2.0318 53.0105
WM35 GDSC1 -1.9055 1.1548 -2.0303 52.918
Mel Ho GDSC1 -1.6671 0.9868 -1.7505 50.2703
UACC-257 GDSC1 -1.6123 1.5296 -1.7803 49.6506
RPMI-7951 GDSC1 -1.5249 0.6785 -1.5659 48.5673
COLO 792 GDSC1 -1.5054 5.5378 -3.0112 49.0415
A-375 GDSC1 -1.4573 0.0887 -1.4635 47.6841
G-mel GDSC1 -1.3793 -0.2754 -1.3799 46.6958
IGR-1 GDSC1 -1.355 0.1043 -1.3599 46.4068
Mel JuSo GDSC1 -1.2803 1.8519 -1.487 45.9787
SK-MEL-30 GDSC1 -1.2413 1.7996 -1.4331 45.5041
LB373-MEL-D GDSC1 -0.9848 1.5286 -1.1018 42.2704
A101D GDSC1 -0.9162 0.4704 -0.9232 40.9436
CP50-MEL-B GDSC1 -0.888 1.7228 -1.0336 41.2208
LB2518-MEL GDSC1 -0.8008 2.5951 -1.1572 40.9939
COLO 783 GDSC1 -0.7815 1.7153 -0.9168 39.8955
SK-MEL-3 GDSC1 -0.7512 1.9306 -0.929 39.7194
WM1552C GDSC1 -0.6544 1.1443 -0.6948 37.864
IST-MEL1 GDSC1 -0.6184 1.2564 -0.6691 37.4737
MMAc-SF GDSC1 -0.6114 2.987 -1.0743 39.2645
WM115 GDSC1 -0.6026 0.5952 -0.6074 37.0141
LOX-IMVI GDSC1 -0.5192 1.3325 -0.5731 36.2601
451Lu GDSC1 -0.4963 1.9389 -0.6536 36.5414
GAK GDSC1 -0.4539 0.9399 -0.4688 35.217
COLO 679 GDSC1 -0.3987 5.1717 -1.7059 39.878
MeWo GDSC1 -0.2509 2.7909 -0.6186 34.6899
SK-MEL-2 GDSC1 -0.2298 2.1046 -0.4015 33.3596
COLO 829 GDSC1 -0.1917 3.126 -0.667 34.5482
WM278 GDSC1 -0.0494 2.3762 -0.2747 31.4624
SK-MEL-24 GDSC1 -0.0215 2.292 -0.2214 30.9666
UACC-62 GDSC1 -0.0181 1.4967 -0.0608 29.9461
HMV-II GDSC1 -0.0114 2.5306 -0.2773 31.2407
M14 GDSC1 0.1051 3.4569 -0.4693 31.6289
SK-MEL-1 GDSC1 0.2459 3.4268 -0.3075 29.8581
WM793 GDSC1 0.3644 1.5378 0.3394 25.0545
Hs 938.T GDSC1 0.5303 2.6183 0.2863 24.428
MZ-MEL-2 GDSC1 0.666 2.4574 0.483 22.3306
SK-MEL-28 GDSC1 0.6686 2.0687 0.5842 21.6391
Hs 940.T GDSC1 0.9199 4.3016 0.0267 24.0658
SK-MEL-5 GDSC1 1.0574 6.9113 -1.0773 29.5912
CP66-MEL GDSC1 1.0673 2.6205 0.8695 17.4325
A2058 GDSC1 1.2015 3.9936 0.4503 19.7397
RVH-421 GDSC1 1.4001 7.4854 -1.0431 27.8651
SH-4 GDSC1 1.4316 7.3049 -0.9254 27.1478
A-388 GDSC1 1.5433 3.6585 0.9461 14.456
COLO 800 GDSC1 4.1746 13.8831 -1.971 22.3963
DJM-1 GDSC1 4.4158 6.881 1.4924 2.0736
HT-144 GDSC1 4.4669 6.0552 1.8358 0.4747
WT2-iPS GDSC1 4.7635 10.7156 -0.0281 10.9447
EquiPSC Line K2 GDSC1 0.783 6.0431 -0.9199 30.1856
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -2.7194 -1.3494 -2.7197 63.3749
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-LMS-1 GDSC1 -3.1304 1.8596 -3.5036 62.9003
EW-8 GDSC1 -2.3307 -0.3448 -2.3408 58.3633
Hs 633.T GDSC1 -1.8443 -0.0932 -1.8525 52.4724
SW872 GDSC1 -1.6583 -0.3738 -1.6596 50.1806
Rh30 GDSC1 -1.5213 0.1856 -1.5318 48.4854
KYM-1 GDSC1 -1.3219 0.4809 -1.3402 46.0377
Rh41 GDSC1 -1.0925 1.666 -1.244 43.6706
G-401 GDSC1 -1.0554 2.9171 -1.534 44.114
RD GDSC1 -0.8256 2.8279 -1.2556 41.5164
SW982 GDSC1 -0.8086 0.5941 -0.8175 39.6115
A-204 GDSC1 -0.541 4.3675 -1.5153 40.2542
MFH-ino GDSC1 -0.4011 2.5514 -0.7084 36.1599
RKN GDSC1 -0.1542 2.3262 -0.3754 32.7207
HT-1080 GDSC1 0.7481 3.5242 0.1861 23.9001
VA-ES-BJ GDSC1 1.2528 2.5913 1.0804 14.9451
MES-SA GDSC1 2.1686 3.4994 1.6216 6.5102
G-402 GDSC1 2.6272 9.7344 -1.1096 23.3479
SW684 GDSC1 3.3226 5.9735 1.2756 5.5829
SK-UT-1 GDSC1 4.0152 7.1089 1.1786 4.7046
GCT GDSC1 4.3391 9.6536 0.1981 10.5519
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RF-48 GDSC1 -4.0285 -0.6203 -4.0783 74.2605
Hs 746.T GDSC1 -3.1898 0.4802 -3.3063 65.7416
NCI-N87 GDSC1 -2.2923 0.3829 -2.3446 57.4955
HSC-39 GDSC1 -1.6464 1.5085 -1.8132 50.0281
AGS GDSC1 -1.4086 -0.2537 -1.4094 47.0624
SNU-1 GDSC1 -1.3423 1.7188 -1.5257 46.6378
GCIY GDSC1 -1.2349 3.6136 -1.9662 46.3279
IM95 GDSC1 -1.228 1.9039 -1.4418 45.4011
23132/87 GDSC1 -1.0536 3.7985 -1.8389 44.7102
TGBC11TKB GDSC1 -0.9478 0.882 -0.9787 41.4576
HGC-27 GDSC1 -0.4508 4.4088 -1.4374 39.4115
NUGC-4 GDSC1 -0.2996 6.838 -2.3555 40.8813
Fu97 GDSC1 -0.0898 2.4334 -0.3347 32.0733
NUGC-3 GDSC1 0.4109 3.9572 -0.347 29.135
TMK-1 GDSC1 0.4466 4.5811 -0.5793 30.2378
MKN1 GDSC1 0.5326 4.0448 -0.2573 27.9196
MKN7 GDSC1 0.6348 3.2477 0.1764 24.5809
ECC10 GDSC1 0.9781 7.988 -1.6771 32.464
SNU-16 GDSC1 1.1392 3.2309 0.7177 18.1255
SNU-5 GDSC1 1.2237 2.6564 1.0269 15.4776
MKN28 GDSC1 1.4838 6.8843 -0.6705 25.583
MKN45 GDSC1 2.376 4.6135 1.244 8.6949
RERF-GC-1B GDSC1 2.8249 8.2247 -0.1972 17.5389
SCH GDSC1 3.3257 5.8118 1.3541 4.9992
OCUM-1 GDSC1 4.2301 6.4683 1.5722 1.8768
SNG-M GDSC1 4.336 12.1414 -1.0007 17.5094
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHT-101 GDSC1 -2.6242 0.5483 -2.7132 60.7171
HTC-C3 GDSC1 -2.1201 1.5735 -2.3396 54.9335
B-CPAP GDSC1 -1.9111 0.5545 -1.9601 53.1553
ML-1 [Human leukemia] GDSC1 -1.7188 0.4164 -1.7477 50.9065
IHH-4 GDSC1 -1.4225 0.1229 -1.429 47.2522
TT2609-C02 GDSC1 -1.3943 0.9929 -1.4611 47.0355
K5 GDSC1 -0.7744 0.8237 -0.7938 39.2428
8505C GDSC1 -0.7689 2.0244 -0.9698 40.0285
CAL-62 GDSC1 -0.6573 3.0512 -1.1455 39.8677
WRO GDSC1 -0.3301 2.3185 -0.5652 34.9365
CGTH-W-1 GDSC1 -0.2417 0.8475 -0.2469 32.5052
FTC-133 GDSC1 1.2751 3.4518 0.7661 17.0867
KMH-2 GDSC1 3.3213 6.111 1.2094 6.0745
ASH-3 GDSC1 3.4567 8.2576 0.2648 12.4888
8305C GDSC1 3.5746 5.9001 1.4671 3.6334
TT GDSC1 4.4596 10.0129 0.1068 10.8372
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Ca9-22 GDSC1 -3.3178 -1.7282 -3.3183 70.5714
PCI-06A GDSC1 -3.0514 -1.7181 -3.0516 67.4906
NCI-H3118 GDSC1 -2.4734 0.03 -2.5058 59.7182
PCI-04B GDSC1 -1.5813 1.4915 -1.7395 49.3027
SCC-25 GDSC1 -1.5716 1.4878 -1.7283 49.194
BICR 78 GDSC1 -1.524 0.5024 -1.551 48.5404
BHY GDSC1 -1.3844 2.611 -1.7984 47.4057
OSC-19 GDSC1 -1.3192 1.3227 -1.4273 46.226
KOSC-2 GDSC1 -1.3057 1.6026 -1.4625 46.1695
JHU-011 GDSC1 -1.1984 0.774 -1.232 44.5652
CAL-27 GDSC1 -1.189 0.3179 -1.1968 44.35
OSC-20 GDSC1 -1.0819 2.9099 -1.5605 44.3904
SCC-9 GDSC1 -1.011 1.7436 -1.1712 42.7378
SAS GDSC1 -0.9182 0.9564 -0.9541 41.1142
HO-1-u-1 GDSC1 -0.6467 2.8269 -1.0606 39.4714
SAT [Human HNSCC] GDSC1 -0.5399 2.0601 -0.7287 37.2308
PCI-38 GDSC1 -0.3075 2.4198 -0.5684 34.8019
HO-1-N-1 GDSC1 -0.2179 1.8997 -0.3429 32.9389
DOK GDSC1 -0.1486 1.9164 -0.271 32.0653
SKN-3 GDSC1 -0.1018 2.1439 -0.2715 31.7723
BB30-HNC GDSC1 -0.0412 2.6352 -0.3414 31.8059
SCC-4 GDSC1 0.0102 2.6122 -0.2783 31.1129
SCC-15 GDSC1 0.1269 3.7231 -0.5501 31.9382
BICR 22 GDSC1 0.1396 1.8702 0.0504 28.2737
CAL-33 GDSC1 0.2068 2.195 0.0525 27.8548
LB771-HNC GDSC1 0.2203 4.4279 -0.7452 32.3904
JHU-022 GDSC1 0.5284 4.9939 -0.6816 30.3279
PE/CA-PJ15 GDSC1 0.7021 3.5006 0.1474 24.4085
BICR 31 GDSC1 0.8076 3.98 0.0549 24.4618
HSC-3 GDSC1 0.9261 2.9129 0.6146 19.9814
HSC-2 GDSC1 1.1042 2.1417 1.0419 16.0518
FaDu GDSC1 1.2006 3.847 0.5155 19.2761
HSC-4 GDSC1 1.2257 4.3964 0.2891 20.7645
Detroit 562 GDSC1 1.4256 4.3738 0.4958 18.3442
KON GDSC1 2.5329 4.148 1.6029 5.3308
BICR 10 GDSC1 2.5489 4.5139 1.4334 6.6078
PCI-30 GDSC1 3.4117 7.8424 0.4352 11.4466
BB49-HNC GDSC1 3.6646 9.6955 -0.2884 15.4332
PCI-15A GDSC1 4.758 6.4351 1.8108 0.4016
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-4 GDSC1 -3.0537 -0.0617 -3.104 65.5726
5637 GDSC1 -2.7822 -0.9956 -2.7851 63.9507
KU-19-19 GDSC1 -1.319 0.1287 -1.324 45.9593
RT-112 GDSC1 -1.1672 2.0715 -1.4151 44.793
SW1710 GDSC1 -0.8974 2.0993 -1.1278 41.6531
HT-1197 GDSC1 -0.7836 1.8233 -0.941 40.0186
CAL-29 GDSC1 -0.7713 0.9394 -0.7989 39.2486
UM-UC-3 GDSC1 -0.1725 3.2104 -0.6762 34.4695
BFTC-905 GDSC1 -0.1556 2.8849 -0.5457 33.6812
TCCSUP GDSC1 -0.061 1.9361 -0.1801 30.9582
T24 GDSC1 0.4711 4.3989 -0.474 29.5226
639V GDSC1 1.4194 4.0604 0.637 17.3394
647V GDSC1 1.8913 6.0802 0.0938 19.1468
J82 GDSC1 2.3437 4.5514 1.2481 8.7792
HT-1376 GDSC1 3.0335 5.9947 1.0658 7.9429
SW780 GDSC1 3.4132 7.3474 0.6771 9.727
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PA-1 GDSC1 -5.0836 -3.3796 -5.0837 89.1603
NEC8 GDSC1 -3.5169 -1.6989 -3.5182 72.659
C-33 A GDSC1 -3.2638 -1.1803 -3.2689 69.3548
SW954 GDSC1 -2.7593 0.0905 -2.8086 62.5892
OVCA420 GDSC1 -2.6437 0.3259 -2.709 61.169
BPH-1 GDSC1 -2.6152 -0.9582 -2.6173 61.9869
DSH1 GDSC1 -2.4399 0.3272 -2.4946 59.1057
OV17R GDSC1 -2.1111 1.2863 -2.2742 55.0129
JAR GDSC1 -2.1027 -0.9994 -2.1029 55.7314
KGN GDSC1 -1.9618 0.7584 -2.0353 53.6694
HEY GDSC1 -1.927 0.9969 -2.0294 53.2033
PEO1 GDSC1 -1.37 2.1859 -1.6652 47.1124
Ca Ski GDSC1 -1.3104 1.574 -1.4621 46.2133
OVMIU GDSC1 -1.2274 0.8906 -1.2732 44.9611
ACC-OV7 GDSC1 -0.9503 2.0181 -1.1659 42.2165
HT-3 GDSC1 -0.8734 1.773 -1.0279 41.082
ME-180 GDSC1 -0.6868 1.2165 -0.7369 38.3192
NT2-D1 GDSC1 -0.6696 1.086 -0.705 38.0257
HEC-1 GDSC1 -0.5595 1.0162 -0.5837 36.5906
LB831-BLC GDSC1 -0.5113 1.8636 -0.6538 36.646
OMC-1 [Human cervical carcinoma] GDSC1 -0.2844 2.5788 -0.5893 34.7592
SKN GDSC1 -0.2411 2.0124 -0.3924 33.3797
UWB1.289 GDSC1 -0.2061 4.4964 -1.2175 37.06
SW962 GDSC1 -0.1153 1.5233 -0.1676 31.22
DoTc2 4510 GDSC1 -0.0663 2.5019 -0.3288 31.8897
OVCA433 GDSC1 0.3319 1.8504 0.2617 25.751
NCC-IT GDSC1 0.3803 2.5482 0.1445 26.2319
CAL-39 GDSC1 0.4982 4.2997 -0.4029 28.9686
SiSo GDSC1 0.7934 3.6556 0.1791 23.7063
HeLa GDSC1 1.1494 3.7922 0.4878 19.7275
JEG-3 GDSC1 1.8353 6.4383 -0.1337 20.8811
MS751 GDSC1 1.8411 5.2821 0.4445 16.8874
SKG-IIIa GDSC1 2.1725 5.7827 0.4875 15.2405
SW756 GDSC1 2.359 5.7543 0.6594 13.2626
JHOS-3 GDSC1 2.77 5.9976 0.8678 10.2624
SiHa GDSC1 3.0515 5.4283 1.3539 5.7084
C-4-I GDSC1 4.151 10.1942 -0.1867 13.4481
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 Clinical pipeline report, company report or official report of Arno Therapeutics.