Details of the Drug

General Information of Drug (ID: DML44FR)

• Drug Name: AR-42
• Synonyms: AR-42; 935881-37-1; OSU-HDAC42; AR 42; (S)-HDAC-42; (S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide; UNII-E0GG29V0AQ; (S)-HDAC 42; E0GG29V0AQ; AR42; HDAC-42; AR-42 (HDAC-42); N-hydroxy-4-{[(2S)-3-methyl-2-phenylbutanoyl]amino}benzamide; N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide; AR-42 (OSU-HDAC42); AC1OCFYN; cc-20; OSU-HDAC 42; MLS006011089; CHEMBL191482; SCHEMBL2348844; OSU-42; DTXSID4042678; NOCAS_42678; CTK8C1969; AOB3995; N-Hydroxy-4-(3-methyl-2-(S)phenyl-butyrylamino)benzamide; MolPort-009-019-571

Indication

Disease Entry	ICD 11	Status	REF
Chronic lymphocytic leukaemia	2A82.0	Phase 1/2	[1]
Multiple myeloma	2A83	Phase 1/2	[1]

• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C18H20N2O3
  Canonical SMILES: CC(C)C(C1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)C(=O)NO
  InChI: InChI=1S/C18H20N2O3/c1-12(2)16(13-6-4-3-5-7-13)18(22)19-15-10-8-14(9-11-15)17(21)20-23/h3-12,16,23H,1-2H3,(H,19,22)(H,20,21)/t16-/m0/s1
  InChIKey: LAMIXXKAWNLXOC-INIZCTEOSA-N
• Cross-matching ID:
  PubChem CID: 6918848
  ChEBI ID: CHEMBL191482
  CAS Number: 935881-37-1
  UNII: E0GG29V0AQ
  DrugBank ID: DB12707
  TTD ID: D07KDI
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug
• Repurposed Drugs (RPD): Click to Jump to the Detailed RPD Information of This Drug

References

• [1] Clinical pipeline report, company report or official report of Arno Therapeutics.