Details of the Drug

General Information of Drug (ID: DML6TAS)

• Drug Name: OPI-1002

Indication

Disease Entry	ICD 11	Status	REF
Acute kidney injury	GB60	Phase 2	[1]

• Drug Type: siRNA drug
• Cross-matching ID: TTD ID: D02CKH

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
P53 messenger RNA (TP53 mRNA)	TT12KOD	P53_HUMAN	Not Available	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Acute kidney injury
• ICD Disease Classification: GB60

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
P53 messenger RNA (TP53 mRNA)	DTT	TP53	7.90E-07	0.3	0.59

References

• [1] 2011 Pipeline of Quark Pharm.