Details of the Drug

General Information of Drug (ID: DMLBYFG)

Drug Name
CZC 24832
Synonyms CZC24832; CZC-24832
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 364.4
Logarithm of the Partition Coefficient (xlogp) 1
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C15H17FN6O2S
IUPAC Name
5-(2-amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide
Canonical SMILES
CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F
InChI
InChI=1S/C15H17FN6O2S/c1-15(2,3)21-25(23,24)11-4-9(6-18-7-11)10-5-12(16)13-19-14(17)20-22(13)8-10/h4-8,21H,1-3H3,(H2,17,20)
InChIKey
RXRZPHQBTHQXSV-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
42623951
CAS Number
1159824-67-5
TTD ID
D06PWI

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase gamma (PIK3CG) DTT PIK3CG 1.98E-01 -0.05 -0.55
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 5.7263 7.8625 2.6079 0.7899
EW-12 GDSC2 3.8562 5.5449 2.618 3.1221
CHSA8926 GDSC2 4.349 11.0591 0.2724 15.6938
CAL-78 GDSC2 4.4948 9.7861 1.0075 11.3398
EW-24 GDSC2 4.5298 6.921 2.4016 3.1107
HOS GDSC2 4.5591 6.4001 2.6506 1.7297
NOS-1 [Human HNSCC] GDSC2 4.5867 8.128 1.8735 6.0642
EW-3 GDSC2 4.6397 7.4544 2.2233 3.9269
MG-63 GDSC2 4.7446 6.7275 2.6077 1.7015
EW-16 GDSC2 4.8889 9.2944 1.519 7.5189
TC-71 GDSC2 4.905 6.5953 2.7411 0.9281
ES6 GDSC2 4.9095 7.366 2.4194 2.4287
MHH-ES-1 GDSC2 5.0635 7.5096 2.4395 2.1222
HuO9 GDSC2 5.0816 9.1177 1.7263 5.955
SaOS-2 GDSC2 5.1414 7.0426 2.6709 1.0005
A-673 GDSC2 5.1539 7.0243 2.6838 0.9392
U-CH2 GDSC2 5.2601 7.4541 2.5606 1.3442
EW-1 GDSC2 5.2684 9.205 1.8007 5.204
NY GDSC2 5.3744 9.0687 1.9252 4.3485
CHSA0108 GDSC2 5.424 12.5936 0.2995 13.0187
SK-PN-DW GDSC2 5.4683 7.7214 2.5498 1.1962
CADO-ES1 GDSC2 5.5014 7.3165 2.7203 0.5724
EW-18 GDSC2 5.6081 7.7748 2.5911 0.9289
G-292 clone A141B1 GDSC2 5.6323 7.98 2.5216 1.1675
HuO-3N1 GDSC2 5.6359 14.2483 -0.3536 15.6645
ES7 GDSC2 5.6426 8.7006 2.2318 2.4123
EW-7 GDSC2 5.646 7.9444 2.5416 1.0805
ES8 GDSC2 5.7292 7.846 2.6154 0.7635
CAL-72 GDSC2 5.7545 7.3774 2.7964 0.2702
EW-11 GDSC2 5.771 8.8442 2.236 2.2447
SK-ES-1 GDSC2 5.7781 7.4041 2.7957 0.2639
ES4 GDSC2 5.8923 7.8602 2.6761 0.4958
H-EMC-SS GDSC2 6.083 8.5723 2.4882 0.9526
U2OS GDSC2 6.1061 8.7769 2.4194 1.1758
EW-13 GDSC2 6.455 8.3258 2.7211 0.2129
ES5 GDSC2 6.616 9.0914 2.5111 0.5916
EW-22 GDSC2 6.6266 8.7429 2.6389 0.3077
CHSA0011 GDSC2 6.6356 8.8116 2.6182 0.344
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 157 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 5.5891 7.3603 2.7393 0.4718
OCI-AML-3 GDSC2 2.9701 6.8809 1.2414 14.1524
SUP-B8 GDSC2 3.1596 6.6516 1.52 11.8563
GDM-1 GDSC2 3.2643 7.0561 1.4066 12.2402
Loucy GDSC2 3.3943 5.9422 2.0716 7.7067
SU-DHL-6 GDSC2 3.4252 5.4809 2.3273 6.0033
Karpas-422 GDSC2 3.5588 5.3191 2.5132 4.4718
NB4 GDSC2 3.5979 5.4519 2.4773 4.5973
Raji GDSC2 3.6003 7.0309 1.6941 9.5034
MOLT-16 GDSC2 3.6009 5.7463 2.3337 5.4911
P12-Ichikawa GDSC2 3.619 7.5594 1.4454 10.9863
GA-10 GDSC2 3.6631 6.7236 1.8964 8.0724
AMO1 GDSC2 3.68 9.4929 0.5295 16.1351
WSU-NHL GDSC2 3.7594 5.6717 2.4887 4.1318
KE-37 GDSC2 3.768 5.2983 2.6763 2.9585
THP-1 GDSC2 3.7766 7.1206 1.7869 8.4588
MLMA GDSC2 3.8139 9.4756 0.6449 15.1295
Farage GDSC2 3.8552 5.7659 2.5108 3.7769
JVM-3 GDSC2 3.8741 8.4963 1.1793 11.9013
NK-92MI GDSC2 3.8823 5.5445 2.6358 2.9594
L-1236 GDSC2 3.9358 8.6353 1.1579 11.8656
RPMI-6666 GDSC2 3.9701 8.5455 1.2287 11.3568
KY821 GDSC2 3.9848 6.5702 2.2116 5.3193
P30/OHK GDSC2 3.9982 5.8999 2.5436 3.2737
A3/Kawakami GDSC2 4.0122 5.5967 2.6954 2.3516
CTV-1 GDSC2 4.0804 8.1178 1.523 9.3115
ALL-PO GDSC2 4.084 9.7278 0.7298 13.9328
RCH-ACV GDSC2 4.0852 6.9412 2.1022 5.7626
Kasumi-1 GDSC2 4.0863 6.5113 2.3105 4.4923
L-363 GDSC2 4.0988 11.7114 -0.2442 18.8879
CCRF-CEM GDSC2 4.1262 8.7975 1.2221 10.998
SUP-M2 GDSC2 4.143 6.7613 2.2291 4.8633
SCC-3 GDSC2 4.1594 6.1114 2.548 2.9331
OCI-AML-2 GDSC2 4.1837 8.0931 1.6109 8.5299
697 GDSC2 4.1959 6.1914 2.5337 2.9487
BONNA-12 GDSC2 4.1994 7.3947 1.9623 6.3588
HAL-01 GDSC2 4.2167 7.3529 1.9947 6.1239
Namalwa GDSC2 4.2249 10.9274 0.243 16.1656
VL51 GDSC2 4.2256 6.4629 2.4256 3.5227
BC-1 GDSC2 4.2839 12.4095 -0.4472 19.3254
HT GDSC2 4.2855 5.6563 2.8262 1.2111
CESS GDSC2 4.3197 6.4639 2.4841 3.0091
H9 GDSC2 4.3557 7.6098 1.9664 5.9928
Karpas-45 GDSC2 4.3816 6.2839 2.6031 2.2396
P32/ISH GDSC2 4.3859 5.8418 2.7993 1.2164
CML-T1 GDSC2 4.4152 7.8506 1.8912 6.3165
ML-2 GDSC2 4.543 7.1211 2.3178 3.561
RPMI-8226 GDSC2 4.5498 7.7684 2.0199 5.2758
CRO-AP2 GDSC2 4.5578 10.1371 0.8814 11.9011
BE-13 GDSC2 4.5797 7.2523 2.2798 3.7124
JeKo-1 GDSC2 4.5804 6.4636 2.6344 1.7826
MHH-CALL-2 GDSC2 4.6115 6.4245 2.6677 1.5754
JVM-2 GDSC2 4.6369 9.2579 1.3655 8.9473
MHH-CALL-4 GDSC2 4.671 7.3221 2.303 3.4236
A4/Fukuda GDSC2 4.6782 6.7716 2.5532 2.0634
MC116 GDSC2 4.6946 5.5376 3.0507 0.1061
KM-H2 GDSC2 4.7042 7.6919 2.1533 4.211
NALM-6 GDSC2 4.7121 7.0748 2.4383 2.6172
Reh GDSC2 4.7207 6.4098 2.7292 1.1589
ST486 GDSC2 4.7335 6.5845 2.6626 1.4505
SIG-M5 GDSC2 4.7342 5.7978 2.9735 0.2557
QIMR-WIL GDSC2 4.7463 7.3407 2.3389 3.1013
Karpas-299 GDSC2 4.7469 6.3719 2.7573 1.009
L-428 GDSC2 4.7655 8.1224 1.9916 5.0261
DoHH2 GDSC2 4.7821 6.1507 2.861 0.5725
SU-DHL-1 GDSC2 4.7988 8.9745 1.6114 7.1673
MOLP-8 GDSC2 4.8016 6.5971 2.6913 1.2422
SU-DHL-4 GDSC2 4.812 11.4191 0.438 13.6952
KOPN-8 GDSC2 4.8166 7.2903 2.4015 2.6561
SUP-B15 GDSC2 4.8171 6.5644 2.7123 1.133
SUP-HD1 GDSC2 4.8346 7.6745 2.2396 3.5032
NU-DUL-1 GDSC2 4.8381 6.7927 2.6279 1.4917
Jiyoye GDSC2 4.8539 7.7929 2.1973 3.7051
Ku812 GDSC2 4.8599 6.9284 2.5817 1.6845
OCI-AML-5 GDSC2 4.8635 6.5144 2.7543 0.9116
DEL GDSC2 4.8672 5.9938 2.9541 0.2467
SU-DHL-10 GDSC2 4.8717 5.9298 2.9786 0.1897
MOLM-13 GDSC2 4.888 6.7231 2.6813 1.1956
OCI-M1 GDSC2 4.8902 5.9026 2.995 0.1512
L-540 GDSC2 4.8956 6.7607 2.6696 1.2394
BC-3 GDSC2 4.9098 7.0282 2.565 1.7043
KMS-12-BM GDSC2 4.916 6.9024 2.6209 1.4357
EoL-1 GDSC2 4.9224 6.6008 2.7469 0.8895
BL-41 GDSC2 4.937 6.3329 2.8571 0.4828
RC-K8 GDSC2 4.9476 6.4689 2.8097 0.6342
CA46 GDSC2 4.9646 7.5193 2.3825 2.5417
MHH-PREB-1 GDSC2 5.0016 7.345 2.4776 2.0136
SU-DHL-5 GDSC2 5.004 6.0784 2.9752 0.1548
IM-9 GDSC2 5.0084 6.36 2.876 0.3856
JURL-MK1 GDSC2 5.0153 6.8901 2.6738 1.1027
HEL GDSC2 5.0826 6.2961 2.9278 0.2241
ME1 GDSC2 5.0874 6.2889 2.9322 0.2132
Karpas-1106P GDSC2 5.0897 7.2398 2.5664 1.4931
VAL GDSC2 5.0966 7.7379 2.3586 2.482
BALL-1 GDSC2 5.1229 7.2694 2.5704 1.4404
JSC-1 GDSC2 5.1264 6.932 2.7078 0.8701
TALL-1 [Human adult T-ALL] GDSC2 5.1395 7.6132 2.4347 2.0503
SKM-1 GDSC2 5.1447 6.3635 2.9272 0.2044
Daudi GDSC2 5.151 6.6037 2.8432 0.4047
RPMI-8866 GDSC2 5.1595 7.5097 2.4886 1.7714
SU-DHL-16 GDSC2 5.1652 6.4311 2.911 0.2311
MM1.S GDSC2 5.1858 7.1289 2.6568 1.0178
TUR GDSC2 5.1902 6.8746 2.7578 0.6447
OPM-2 GDSC2 5.2251 6.7755 2.8095 0.4618
MOLT-4 GDSC2 5.2251 6.7962 2.8018 0.4843
HL-60 GDSC2 5.2391 6.4744 2.923 0.1834
MEG-01 GDSC2 5.285 7.1141 2.7064 0.7551
Jurkat GDSC2 5.3083 6.921 2.7891 0.4761
U-698-M GDSC2 5.3154 6.9916 2.7657 0.5416
TK [Human B-cell lymphoma] GDSC2 5.3193 7.1203 2.7187 0.6895
LAMA-84 GDSC2 5.3204 10.6203 1.1736 8.6017
DND-41 GDSC2 5.3488 7.2598 2.6778 0.8099
OCI-Ly7 GDSC2 5.3493 6.6199 2.9125 0.1716
Ramos.2G6.4C10 GDSC2 5.3533 6.6567 2.9012 0.1908
JJN-3 GDSC2 5.3539 7.3121 2.6597 0.871
U266B1 GDSC2 5.3662 7.1185 2.739 0.5941
SK-MM-2 GDSC2 5.3789 7.7147 2.5109 1.4391
Karpas-231 GDSC2 5.4171 6.814 2.8696 0.232
SU-DHL-8 GDSC2 5.4287 6.9357 2.8308 0.3118
GR-ST GDSC2 5.444 7.7853 2.513 1.3681
PL-21 GDSC2 5.4567 8.1585 2.3658 2.002
EM-2 GDSC2 5.4659 6.9883 2.8261 0.3081
RL GDSC2 5.469 6.6735 2.9365 0.1084
WIL2 NS GDSC2 5.4719 7.0099 2.8207 0.3182
RS4;11 GDSC2 5.4732 7.5893 2.6041 0.9836
Karpas-620 GDSC2 5.5329 7.0238 2.8387 0.2568
EB2 GDSC2 5.584 7.2798 2.7666 0.4025
NCI-H929 GDSC2 5.5987 7.0225 2.8632 0.1909
NOMO-1 GDSC2 5.599 7.2665 2.7772 0.3699
SUP-T1 GDSC2 5.5992 7.2773 2.7734 0.379
K-562 GDSC2 5.6373 7.3665 2.7559 0.406
MY-M12 GDSC2 5.644 7.8302 2.5851 0.9238
OCI-Ly19 GDSC2 5.6697 7.5635 2.6967 0.5496
SR GDSC2 5.6995 7.8456 2.603 0.8237
ROS-50 GDSC2 5.7082 7.694 2.6638 0.6249
PF-382 GDSC2 5.7179 7.3426 2.7951 0.285
MOLM-16 GDSC2 5.727 7.4654 2.7548 0.371
LP-1 GDSC2 5.7313 7.5243 2.7353 0.4167
ATN-1 GDSC2 5.7431 7.3196 2.8124 0.2424
CTB-1 GDSC2 5.7696 7.7181 2.6796 0.5461
DG-75 GDSC2 5.7727 8.1121 2.5319 1.019
KG-1 GDSC2 5.7933 7.4869 2.7722 0.3072
DB GDSC2 5.7963 7.5499 2.7509 0.3529
ARH-77 GDSC2 5.8114 7.6399 2.7245 0.4091
KMOE-2 GDSC2 5.8373 7.5724 2.7584 0.3211
MOLT-13 GDSC2 5.8544 7.599 2.7554 0.3217
ALL-SIL GDSC2 5.8715 7.7335 2.7139 0.4098
EJM GDSC2 5.8792 7.3334 2.8563 0.138
HC-1 GDSC2 5.8964 7.5674 2.782 0.2542
MN-60 GDSC2 5.9942 7.6133 2.8014 0.1942
Hs 445 GDSC2 5.9951 7.3629 2.8862 0.0847
Granta-519 GDSC2 6.03 7.5998 2.8187 0.1601
KCL-22 GDSC2 6.1352 7.9554 2.734 0.274
HDLM-2 GDSC2 6.1424 8.1633 2.6632 0.4203
KMS-11 GDSC2 6.1766 8.3716 2.6012 0.5596
HH [Human lymphoma] GDSC2 6.2141 8.7455 2.4775 0.9029
LC4-1 GDSC2 6.6787 8.7797 2.645 0.2825
⏷ Show the Full List of 157 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 3.6702 7.3344 1.598 9.9092
FLO-1 GDSC2 4.1579 7.8869 1.6931 8.0923
KYAE-1 GDSC2 4.8762 9.8946 1.2233 9.2428
ESO-26 GDSC2 5.5167 7.878 2.5094 1.3156
ESO-51 GDSC2 5.5817 7.6246 2.6374 0.7869
HCE-4 GDSC2 5.6233 9.1826 2.0144 3.5086
OACM5.1 C GDSC2 5.823 13.6012 0.0876 13.2116
KYSE-50 GDSC2 5.9382 8.2452 2.5516 0.8377
TE-12 GDSC2 5.9449 8.725 2.3677 1.504
SK-GT-4 GDSC2 5.9721 14.4453 -0.2161 14.3256
OACP4 C GDSC2 6.48 8.2911 2.7417 0.1774
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 4.4933 7.6037 2.0609 5.1466
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 GDSC2 3.9704 6.5723 2.2004 5.4214
KP-N-RT-BM-1 GDSC2 4.117 7.2273 1.9856 6.4031
SJNB-10 GDSC2 4.2629 13.2375 -0.8751 21.2163
Kelly GDSC2 4.4765 6.3081 2.6458 1.8688
GOTO GDSC2 4.5012 7.6438 2.047 5.2123
MHH-NB-11 GDSC2 4.7996 6.7943 2.6076 1.6337
KP-N-YN GDSC2 4.9369 8.0512 2.1291 3.9448
CHP-126 GDSC2 4.9509 6.8822 2.6463 1.2843
SJNB-7 GDSC2 5.1263 6.6991 2.7976 0.5554
SJNB-6 GDSC2 5.1459 6.7158 2.7994 0.5377
SJNB-14 GDSC2 5.1805 7.5532 2.4809 1.783
SK-N-MC-IXC GDSC2 5.2256 6.2637 2.9903 0.0836
CHP-134 GDSC2 5.2558 7.1056 2.697 0.8096
SK-N-DZ GDSC2 5.2659 6.5888 2.8928 0.2347
SK-N-AS GDSC2 5.2804 6.7455 2.8423 0.3456
IMR-5 GDSC2 5.3333 7.1264 2.7223 0.6684
NH-12 GDSC2 5.3814 6.9663 2.8015 0.405
SJNB-5 GDSC2 5.437 7.5245 2.6134 0.9773
TGW GDSC2 5.4455 7.3874 2.6702 0.7682
SK-N-BE(2)-M17 GDSC2 5.4527 7.1422 2.7652 0.4685
NB(TU)1 GDSC2 5.4613 7.1726 2.7575 0.4857
SJNB-17 GDSC2 5.4997 7.5253 2.6405 0.8329
KP-N-YS GDSC2 5.7936 7.9806 2.5913 0.8007
SJNB-13 GDSC2 5.8196 7.5023 2.7766 0.2891
LA-N-6 GDSC2 6.0151 8.0754 2.6458 0.5178
SiMa GDSC2 6.0665 8.3656 2.5593 0.7358
GI-ME-N GDSC2 6.1441 10.6542 1.6547 4.6033
NB69 GDSC2 6.4092 18.5814 -1.9131 20.1397
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 5.1226 7.558 2.4495 1.9997
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BT-20 GDSC2 3.7867 7.1451 1.7825 8.4599
BT-549 GDSC2 4.053 6.8237 2.1365 5.6252
DU4475 GDSC2 4.0707 6.8654 2.1288 5.6324
HCC70 GDSC2 4.2726 6.3499 2.5078 2.9581
HCC1500 GDSC2 4.2931 6.4818 2.4593 3.1994
YMB-1-E GDSC2 4.3279 7.2949 2.0983 5.2605
Hs 578T GDSC2 4.3407 8.0088 1.7636 7.2452
JIMT-1 GDSC2 4.4475 7.5235 2.0689 5.191
HCC1937 GDSC2 4.807 9.1841 1.517 7.6993
CAMA-1 GDSC2 4.8281 7.7023 2.2233 3.6042
MDA-MB-468 GDSC2 4.8452 9.1451 1.561 7.365
HCC2157 GDSC2 4.8996 12.4962 -0.0261 15.8185
Evsa-T GDSC2 4.9367 6.7302 2.7015 1.0613
HCC1806 GDSC2 5.0066 7.1679 2.5552 1.6367
HDQ-P1 GDSC2 5.0539 7.3121 2.5184 1.754
CAL-120 GDSC2 5.07 6.4884 2.8533 0.4182
T-47D GDSC2 5.0835 8.1988 2.148 3.6046
BT-474 GDSC2 5.1279 6.7349 2.7847 0.5962
OCUB-M GDSC2 5.1613 10.5592 1.0976 9.3466
CAL-51 GDSC2 5.2276 7.0474 2.7074 0.7935
HCC1187 GDSC2 5.3754 6.8816 2.8298 0.3358
MRK-nu-1 GDSC2 5.3936 6.7908 2.8691 0.2408
CAL-85-1 GDSC2 5.4387 11.8737 0.6556 11.1579
HCC1428 GDSC2 5.4648 6.8789 2.8644 0.2272
MDA-MB-436 GDSC2 5.4786 7.8276 2.5121 1.3397
MFM-223 GDSC2 5.5033 7.0863 2.8053 0.3418
HCC1569 GDSC2 5.5366 9.41 1.8654 4.4145
EFM-19 GDSC2 5.5543 7.6781 2.6051 0.9183
HCC1954 GDSC2 5.5751 7.2256 2.7828 0.3663
MDA-MB-157 GDSC2 5.5891 8.5452 2.2701 2.2948
HCC1419 GDSC2 5.5913 7.6036 2.6495 0.7406
EFM-192A GDSC2 5.6226 7.4617 2.7154 0.5212
MCF-7 GDSC2 5.6494 7.7678 2.6115 0.8288
HCC38 GDSC2 5.6989 7.6576 2.6736 0.6011
MDA-MB-330 GDSC2 5.7502 8.0104 2.5615 0.9308
MDA-MB-415 GDSC2 5.8407 7.5904 2.7533 0.3311
ZR-75-30 GDSC2 5.8686 8.7077 2.3393 1.6905
UACC-893 GDSC2 5.8945 8.1274 2.5779 0.7806
HCC2218 GDSC2 5.9169 7.6726 2.7527 0.3058
COLO 824 GDSC2 5.9394 7.912 2.6757 0.4753
HCC1599 GDSC2 5.9752 7.692 2.7674 0.2585
AU565 GDSC2 6.0112 8.483 2.4918 0.9891
MDA-MB-453 GDSC2 6.0762 8.1776 2.6325 0.5243
MDA-MB-231 GDSC2 6.1347 7.7633 2.7999 0.1654
HCC1143 GDSC2 6.1493 8.5699 2.5168 0.8179
MDA-MB-361 GDSC2 6.1812 15.1615 -0.4179 14.8007
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-247MG GDSC2 3.6937 6.5733 1.9947 7.378
PFSK-1 GDSC2 4.0459 6.1395 2.4612 3.6694
8-MG-BA GDSC2 4.1344 5.8717 2.6437 2.4273
LN-18 GDSC2 4.2326 9.9517 0.7321 13.5358
AM-38 GDSC2 4.2597 7.9526 1.7339 7.6078
SK-MG-1 GDSC2 4.3388 6.302 2.5698 2.4921
LN-405 GDSC2 4.555 6.7948 2.4736 2.6704
D-245MG GDSC2 4.6189 8.458 1.7378 6.7991
Daoy GDSC2 4.7412 6.5238 2.6919 1.3054
A-172 GDSC2 4.7538 8.1342 1.9787 5.122
Becker GDSC2 4.7943 6.8393 2.5857 1.7462
D-263MG GDSC2 4.8725 8.8077 1.7385 6.2828
D-423MG GDSC2 4.9004 7.9459 2.1553 3.8605
D-542MG GDSC2 4.9191 6.7627 2.68 1.1699
42-MG-BA GDSC2 4.9487 6.7712 2.6906 1.0956
U-87MG ATCC GDSC2 4.9658 6.804 2.6854 1.1013
DBTRG-05MG GDSC2 5.072 7.0653 2.6295 1.2349
GB-1 GDSC2 5.0892 6.779 2.7512 0.7387
CAS-1 GDSC2 5.1061 6.6189 2.8194 0.499
D-392MG GDSC2 5.2285 12.8201 0.0527 14.671
D283 Med GDSC2 5.2289 6.6672 2.8507 0.3473
Hs 683 GDSC2 5.2323 6.5755 2.8849 0.2638
KNS-81-FD GDSC2 5.2527 7.4989 2.5388 1.4448
GI-1 GDSC2 5.2553 6.9409 2.7599 0.5956
ONS-76 GDSC2 5.2867 7.0507 2.7315 0.6685
KNS-42 GDSC2 5.2869 6.7143 2.856 0.3093
SF268 GDSC2 5.3066 7.4259 2.5936 1.1637
NMC-G1 GDSC2 5.3211 6.849 2.8206 0.383
SF295 GDSC2 5.3404 6.6653 2.8934 0.2093
D-566MG GDSC2 5.3541 6.8605 2.8293 0.3461
U-251MG GDSC2 5.3934 6.7784 2.8733 0.2322
YH-13 GDSC2 5.4003 7.3979 2.6467 0.8834
H4 GDSC2 5.4168 13.4255 -0.1084 15.0187
KINGS-1 GDSC2 5.453 14.3519 -0.5337 16.8688
SF126 GDSC2 5.4697 6.9257 2.8498 0.2552
GaMG GDSC2 5.5142 10.6589 1.2798 7.6421
SF539 GDSC2 5.5554 13.5554 -0.0741 14.5518
DK-MG GDSC2 5.586 7.031 2.8557 0.2077
T98G GDSC2 5.5919 7.2148 2.7931 0.3352
YKG-1 GDSC2 5.66 7.1234 2.8504 0.1968
LN-229 GDSC2 5.6811 7.5839 2.6937 0.5521
U-118MG GDSC2 5.7129 7.189 2.8468 0.1893
D-502MG GDSC2 5.843 7.8783 2.6499 0.5921
SW1088 GDSC2 5.8985 7.6615 2.7498 0.3181
SNB-75 GDSC2 5.9153 8.4392 2.4671 1.1466
M059J GDSC2 5.9273 7.6224 2.7741 0.2599
D-336MG GDSC2 5.9846 8.1014 2.6242 0.5911
KS-1 [Human Krukenberg tumour] GDSC2 6.0667 8.4145 2.5411 0.7917
Onda 11 GDSC2 6.1477 8.4805 2.5496 0.7191
Onda 10 GDSC2 6.1819 7.7212 2.8305 0.1176
KALS-1 GDSC2 6.7937 9.5628 2.4089 0.7798
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC2 4.6103 7.4484 2.208 4.0674
TGBC24TKB GDSC2 6.127 8.4938 2.5362 0.7713
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC2 4.5075 6.1542 2.7291 1.4059
EN GDSC2 4.6193 6.1491 2.7873 1.0077
MFE-296 GDSC2 4.6476 7.041 2.4165 2.8347
KLE GDSC2 4.9823 10.8052 0.8574 11.058
RL95-2 GDSC2 5.0298 7.372 2.4808 1.963
MFE-319 GDSC2 5.3023 7.1209 2.7112 0.7264
MFE-280 GDSC2 5.6381 8.1813 2.4439 1.4724
AN3-CA GDSC2 5.6642 11.6286 0.9207 9.2985
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-498 GDSC2 3.9692 6.7537 2.111 5.9743
RCC10RGB GDSC2 4.045 6.0236 2.5158 3.3449
KTCTL-1M GDSC2 4.4435 7.1822 2.2272 4.2663
LB996-RCC GDSC2 4.4974 7.6562 2.0387 5.2692
SW13 GDSC2 4.5185 11.2957 0.283 15.2104
BFTC-909 GDSC2 4.6157 6.6034 2.5926 1.9475
CAL-54 GDSC2 4.6571 10.7785 0.6394 12.9941
KTCTL-13 GDSC2 4.8506 7.9919 2.1045 4.2296
KTCTL-26A GDSC2 4.9076 7.2232 2.4805 2.1209
BB65-RCC GDSC2 5.1245 7.6884 2.3948 2.2642
Caki-1 GDSC2 5.1713 8.2209 2.1879 3.2585
OS-RC-2 GDSC2 5.3124 7.0876 2.7282 0.6623
NCC010 GDSC2 5.4307 8.5852 2.1704 2.9816
KMRC-20 GDSC2 5.441 10.2483 1.4251 6.9782
KTCTL-21 GDSC2 5.4636 8.3886 2.2722 2.4357
ACHN GDSC2 5.5981 7.5511 2.6722 0.6636
SN12C GDSC2 5.6058 7.5044 2.6928 0.596
HA7-RCC GDSC2 5.6127 8.335 2.3693 1.8168
LB2241-RCC GDSC2 5.6846 7.5445 2.7096 0.5058
786-O GDSC2 5.7482 7.3377 2.808 0.2494
A-704 GDSC2 5.82 7.5036 2.7763 0.2895
769-P GDSC2 5.8388 7.7437 2.6975 0.4646
UO-31 GDSC2 5.9082 7.5652 2.7871 0.2413
KTCTL-195 GDSC2 5.9167 7.9192 2.6641 0.5158
LB1047-RCC GDSC2 5.9508 8.3346 2.5229 0.9246
NCC021 GDSC2 5.9545 7.9435 2.6701 0.4827
RXF 393L GDSC2 6.1744 8.6896 2.4821 0.9131
VMRC-RCZ GDSC2 6.3181 8.0867 2.7543 0.193
SW156 GDSC2 6.3421 8.6411 2.5679 0.5699
VMRC-RCW GDSC2 6.3854 8.0475 2.791 0.1312
KTCTL-140 GDSC2 6.5123 8.65 2.6294 0.3609
TK-10 GDSC2 6.7425 8.8117 2.6568 0.2468
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo GDSC2 4.3263 7.7435 1.8819 6.5648
LS123 GDSC2 4.5733 6.4101 2.6538 1.6943
C2BBe1 GDSC2 4.5911 8.2773 1.8054 6.4575
LS513 GDSC2 4.6606 6.345 2.7264 1.237
HT-55 GDSC2 4.6748 6.5263 2.6572 1.5473
CL-11 GDSC2 4.6807 9.0275 1.5067 8.0266
HCT 15 GDSC2 4.7384 6.7127 2.6108 1.6941
HT-29 GDSC2 4.7624 5.9327 2.9352 0.3462
SW1116 GDSC2 4.8405 6.9504 2.5623 1.8023
NCI-H508 GDSC2 4.9741 7.1414 2.5499 1.6995
T84 GDSC2 4.9812 7.1901 2.533 1.7713
COLO205 GDSC2 4.9856 6.1459 2.9447 0.2222
SW1417 GDSC2 4.9876 6.9132 2.6513 1.225
KM12 GDSC2 4.9932 7.0136 2.6128 1.3887
SNU-C5 GDSC2 4.9984 7.8881 2.2383 3.2509
GP5d GDSC2 5.0322 7.3429 2.4943 1.8946
SNU-81 GDSC2 5.068 7.1072 2.6105 1.3208
SW1463 GDSC2 5.1623 6.6811 2.8191 0.4679
SNU-1040 GDSC2 5.1667 6.5373 2.8736 0.317
HCT 116 GDSC2 5.1694 6.7306 2.8035 0.5108
MDST8 GDSC2 5.1827 6.3347 2.951 0.1491
HT115 GDSC2 5.2372 6.7924 2.8081 0.4593
SW948 GDSC2 5.3098 7.0696 2.734 0.6452
SW48 GDSC2 5.3868 7.2439 2.7001 0.7069
SNU-283 GDSC2 5.4122 7.0359 2.7882 0.4259
SK-CO-1 GDSC2 5.4455 7.0826 2.7842 0.4204
RKO GDSC2 5.4732 7.5481 2.6202 0.9245
SW837 GDSC2 5.5033 7.2716 2.7378 0.5199
CaR-1 GDSC2 5.5508 7.8507 2.5359 1.1802
LS411N GDSC2 5.5832 6.6791 2.9736 0.0534
RCM-1 [Human ESC] GDSC2 5.6354 6.8844 2.923 0.0967
COLO 678 GDSC2 5.6612 7.7801 2.6118 0.8198
NCI-H716 GDSC2 5.694 7.3313 2.7901 0.3037
LS1034 GDSC2 5.6986 6.9818 2.9122 0.0993
SNU-61 GDSC2 5.7027 7.6661 2.6719 0.6038
HCC2998 GDSC2 5.7379 7.7787 2.6443 0.667
CW-2 GDSC2 5.7398 7.5708 2.7217 0.4473
SNU-C1 GDSC2 5.757 8.0176 2.5616 0.9254
COLO 320HSR GDSC2 5.7683 7.7153 2.6801 0.5454
LS180 GDSC2 5.7864 7.1927 2.8715 0.1352
SNU-407 GDSC2 5.8731 7.8479 2.673 0.5129
NCI-H747 GDSC2 5.9438 7.8816 2.6883 0.4416
CCK-81 GDSC2 6.0572 8.1659 2.6294 0.5415
SNU-175 GDSC2 6.0839 7.8655 2.7466 0.2654
SW620 GDSC2 6.101 7.6069 2.8409 0.1182
SW626 GDSC2 6.1237 8.7002 2.4566 1.032
DiFi GDSC2 6.2244 8.4688 2.5845 0.5812
SNU-C2B GDSC2 6.3261 10.0926 1.9912 2.7409
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 5.7817 7.604 2.726 0.4181
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-6 GDSC2 3.8614 5.3555 2.712 2.5463
SNU-423 GDSC2 4.0704 9.0048 1.0776 11.9867
SNU-398 GDSC2 4.5921 6.8762 2.4585 2.6937
HuH-1 GDSC2 4.6086 7.4226 2.2189 4.0078
JHH-4 GDSC2 4.7034 8.3714 1.8348 6.0565
Huh-7 GDSC2 4.7218 6.7112 2.6027 1.7549
SNU-387 GDSC2 4.8739 8.1625 2.0402 4.5512
JHH-1 GDSC2 4.9946 6.2061 2.9266 0.2602
Hep 3B2.1-7 GDSC2 5.0049 6.527 2.8119 0.5868
SK-HEP-1 GDSC2 5.1187 6.5084 2.8653 0.3602
JHH-2 GDSC2 5.2097 9.5851 1.589 6.4926
JHH-7 GDSC2 5.8789 7.4167 2.8278 0.1797
Hep-G2/C3A GDSC2 5.9081 7.3382 2.8647 0.1217
HLE GDSC2 6.0499 8.1255 2.6412 0.5139
SNU-449 GDSC2 6.1109 8.052 2.691 0.3694
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 166 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC78 GDSC2 3.8545 7.1557 1.8288 8.0002
NCI-H2122 GDSC2 3.8842 6.5685 2.14 5.9965
NCI-H1563 GDSC2 3.8915 6.8086 2.0275 6.6766
NCI-H1755 GDSC2 3.934 10.6229 0.1681 17.3265
NCI-H2731 GDSC2 3.9903 6.3256 2.334 4.5577
BEN GDSC2 4.0539 5.2591 2.8739 1.2866
LXF 289 GDSC2 4.151 6.4413 2.3873 3.8965
COR-L311 GDSC2 4.2228 7.4711 1.9417 6.4314
IST-SL2 GDSC2 4.2706 10.9201 0.2816 15.8483
NCI-H1781 GDSC2 4.2824 6.226 2.5708 2.582
NCI-H2030 GDSC2 4.373 15.1201 -1.7257 24.1231
NCI-H345 GDSC2 4.4526 5.3103 3.0407 0.2106
NCI-H522 GDSC2 4.4874 8.0874 1.8265 6.5493
NCI-H2444 GDSC2 4.5011 5.6692 2.9252 0.5512
KNS-62 GDSC2 4.5179 6.7674 2.4644 2.7812
HCC366 GDSC2 4.534 7.0126 2.3622 3.3248
EPLC-272H GDSC2 4.5443 6.5981 2.5554 2.2454
CAL-12T GDSC2 4.572 7.3101 2.2483 3.9054
SHP-77 GDSC2 4.6035 6.8918 2.458 2.6786
NCI-H82 GDSC2 4.6055 6.0056 2.8391 0.8009
NCI-H446 GDSC2 4.607 7.6356 2.1189 4.587
NCI-H1048 GDSC2 4.6126 6.5402 2.6185 1.8197
NCI-H838 GDSC2 4.6471 6.3159 2.7319 1.2271
SBC-5 GDSC2 4.688 5.6987 2.9914 0.231
NCI-H2085 GDSC2 4.7134 9.1002 1.4941 8.0303
RERF-LC-KJ GDSC2 4.7268 7.295 2.3481 3.0821
NCI-H720 GDSC2 4.7642 6.0198 2.9034 0.4421
NCI-H2170 GDSC2 4.7987 8.5487 1.8129 5.9959
NCI-H2291 GDSC2 4.7987 7.4931 2.3006 3.2265
NCI-H526 GDSC2 4.8235 6.1069 2.8952 0.4319
DMS 273 GDSC2 4.8296 7.4236 2.3495 2.9131
NCI-H1793 GDSC2 4.8659 7.1953 2.4702 2.2287
NCI-H460 GDSC2 4.8679 6.1653 2.8915 0.4171
NCI-H596 GDSC2 4.8798 6.9142 2.5979 1.5841
DMS 53 GDSC2 4.8814 7.2164 2.4694 2.2119
IA-LM GDSC2 4.8929 6.5306 2.7613 0.8577
NCI-H226 GDSC2 4.9024 16.2664 -1.885 23.3595
NCI-H2227 GDSC2 4.9083 7.3383 2.4309 2.3715
SBC-3 GDSC2 4.9355 7.0198 2.5816 1.5957
NCI-H2141 GDSC2 4.936 7.0967 2.5494 1.7474
Lu-139 GDSC2 4.944 7.3976 2.4243 2.3557
NCI-H1435 GDSC2 4.9446 6.7284 2.706 1.0354
NCI-H1666 GDSC2 4.9745 12.6267 -0.0354 15.6857
NCI-H1975 GDSC2 4.9822 9.5857 1.4421 7.7704
SK-LU-1 GDSC2 4.9947 8.9404 1.7543 5.9581
SBC-1 GDSC2 4.9979 6.4629 2.8333 0.5209
HOP-62 GDSC2 5.0122 6.8673 2.6815 1.0734
NCI-H2369 GDSC2 5.013 6.3665 2.8755 0.3849
NCI-H2171 GDSC2 5.0201 6.7546 2.7301 0.8718
NCI-H250 GDSC2 5.0316 7.2041 2.5525 1.6207
EBC-1 GDSC2 5.043 9.0864 1.7167 6.0818
HCC827 GDSC2 5.0484 7.2086 2.559 1.5718
NCI-H1105 GDSC2 5.0547 6.6283 2.7944 0.6125
COR-L303 GDSC2 5.0574 6.3714 2.8912 0.3208
NCI-H1915 GDSC2 5.0678 7.057 2.6309 1.2332
NCI-H1963 GDSC2 5.071 7.6525 2.382 2.3984
COR-L23 GDSC2 5.0717 7.1165 2.6084 1.326
COR-L321 GDSC2 5.1097 6.7651 2.7654 0.6739
NCI-H2087 GDSC2 5.1202 7.8759 2.3114 2.6898
NCI-H1836 GDSC2 5.1404 6.6119 2.8359 0.4306
NCI-H2081 GDSC2 5.1479 7.0321 2.678 0.9669
NCI-H1581 GDSC2 5.1501 7.5491 2.4673 1.882
NCI-H2135 GDSC2 5.1539 6.6177 2.8392 0.4144
UMC-11 GDSC2 5.1591 6.7273 2.8005 0.5262
NCI-H1650 GDSC2 5.1655 9.4929 1.6041 6.4903
NCI-H2110 GDSC2 5.1783 9.9792 1.3841 7.7077
SW1271 GDSC2 5.1859 8.9569 1.8646 4.9916
PC-14 GDSC2 5.2134 7.3656 2.5744 1.331
CPC-N GDSC2 5.2326 7.5113 2.524 1.5303
EMC-BAC-2 GDSC2 5.2382 8.0277 2.3088 2.5433
Lu-134-A GDSC2 5.2397 11.5296 0.6855 11.4229
LCLC-103H GDSC2 5.2494 7.3253 2.6075 1.159
NCI-H1436 GDSC2 5.263 7.0281 2.7301 0.6891
NCI-H2373 GDSC2 5.2715 6.9942 2.7465 0.6288
NCI-H2595 GDSC2 5.2746 7.3873 2.5943 1.1899
COLO 668 GDSC2 5.2825 7.0895 2.7148 0.7277
NCI-H1299 GDSC2 5.3003 11.7241 0.6334 11.568
NCI-H1568 GDSC2 5.3055 8.3463 2.2068 2.9682
NCI-H650 GDSC2 5.3172 10.6167 1.1732 8.6103
NCI-H1993 GDSC2 5.3216 7.0171 2.7587 0.5593
Lu-165 GDSC2 5.3336 7.0123 2.7654 0.532
NCI-H2722 GDSC2 5.3858 7.3409 2.6625 0.8373
RERF-LC-Sq1 GDSC2 5.3881 9.2961 1.8305 4.8392
NCI-H2591 GDSC2 5.3915 8.7848 2.0614 3.5979
NCI-H2795 GDSC2 5.3955 9.2572 1.8525 4.7079
ChaGo-K-1 GDSC2 5.3964 7.6206 2.5571 1.2308
NCI-H292 GDSC2 5.3985 7.1325 2.747 0.5505
DMS 79 GDSC2 5.406 7.2032 2.7236 0.6183
NCI-H3122 GDSC2 5.4128 8.3283 2.2716 2.5021
NCI-H146 GDSC2 5.4275 6.9366 2.83 0.3142
NCI-H1155 GDSC2 5.4365 7.2387 2.7229 0.6022
NCI-H2803 GDSC2 5.4431 7.1753 2.7492 0.5193
HCC15 GDSC2 5.4444 8.82 2.0753 3.449
HARA [Human squamous cell lung carcinoma] GDSC2 5.4482 7.2388 2.7276 0.5808
LOU-NH91 GDSC2 5.4582 7.1187 2.7761 0.4361
NCI-H1770 GDSC2 5.4703 6.7712 2.9037 0.1557
NCI-H1876 GDSC2 5.4725 7.0129 2.8199 0.32
HCC44 GDSC2 5.4845 7.5494 2.6246 0.9
NCI-H661 GDSC2 5.4942 7.3812 2.6931 0.6609
NCI-H2461 GDSC2 5.4984 7.9429 2.4748 1.4762
NCI-H1623 GDSC2 5.509 7.6535 2.5948 0.99
Calu-3 GDSC2 5.5104 7.6135 2.611 0.9297
VMRC-LCD GDSC2 5.5142 7.3479 2.7138 0.5846
NCI-H1651 GDSC2 5.5166 14.3613 -0.4929 16.5472
NCI-H2023 GDSC2 5.5207 7.6551 2.5994 0.9642
NCI-H2172 GDSC2 5.5552 7.1627 2.7977 0.3389
NCI-H841 GDSC2 5.5647 7.3962 2.7164 0.5489
Ms-1 GDSC2 5.5678 7.0342 2.8479 0.2275
NCI-H2196 GDSC2 5.5735 7.3158 2.7495 0.4521
SK-MES-1 GDSC2 5.5774 9.3952 1.8952 4.1942
LCLC-97TM1 GDSC2 5.5851 8.3006 2.37 1.8425
NCI-H196 GDSC2 5.6151 9.594 1.828 4.4913
NCI-H2405 GDSC2 5.6233 10.4347 1.4513 6.5073
NCI-H1437 GDSC2 5.6301 7.1996 2.8128 0.2777
RERF-LC-MS GDSC2 5.6376 7.0706 2.8605 0.1853
NCI-H1092 GDSC2 5.638 7.1412 2.8362 0.2287
NCI-H2228 GDSC2 5.6381 7.9321 2.543 1.0817
NCI-H2818 GDSC2 5.6386 8.0005 2.5163 1.1828
NCI-H290 GDSC2 5.6474 7.3558 2.7637 0.3826
HCC33 GDSC2 5.6628 6.9441 2.9125 0.1047
A-549 GDSC2 5.6805 13.0171 0.2712 12.6135
Lu-65 GDSC2 5.6814 7.4535 2.7415 0.4229
NCI-H1869 GDSC2 5.7004 7.4667 2.7441 0.4081
NCI-H23 GDSC2 5.7531 8.1506 2.5083 1.1203
Calu-6 GDSC2 5.7582 7.5455 2.738 0.3985
IST-SL1 GDSC2 5.7727 8.145 2.5192 1.0653
COR-L105 GDSC2 5.7896 13.9754 -0.115 14.2407
NCI-H1693 GDSC2 5.7969 7.4659 2.7809 0.2877
NCI-H520 GDSC2 5.8065 7.7415 2.6857 0.5111
Lu-135 GDSC2 5.8103 7.4173 2.8029 0.2404
NCI-H1355 GDSC2 5.8106 8.4864 2.4014 1.4884
NCI-H810 GDSC2 5.8182 7.3394 2.8327 0.1863
NCI-H322M GDSC2 5.837 15.6438 -0.8896 17.5269
NCI-H2804 GDSC2 5.8381 8.0842 2.5707 0.8397
NCI-H2029 GDSC2 5.861 7.1676 2.9056 0.0829
HOP-92 GDSC2 5.8631 16.2727 -1.1772 18.615
NCI-H3255 GDSC2 5.8652 7.605 2.7573 0.3137
NCI-H358 GDSC2 5.8733 7.8644 2.667 0.5289
DMS 114 GDSC2 5.8903 7.5323 2.792 0.2374
NCI-H647 GDSC2 5.9069 7.6621 2.7527 0.3092
COR-L32 GDSC2 5.9284 7.9199 2.6685 0.4988
NCI-H524 GDSC2 5.9603 7.8676 2.6997 0.4073
NCI-H1734 GDSC2 5.973 7.7213 2.7563 0.2803
LK-2 GDSC2 5.9952 8.0886 2.6332 0.5612
NCI-H510A GDSC2 5.9982 7.7262 2.7638 0.2583
A-427 GDSC2 6.0118 9.6769 2.0072 3.0345
NCI-H441 GDSC2 6.0263 12.0603 0.9482 8.4745
NCI-H1694 GDSC2 6.0301 7.4764 2.8603 0.1071
NCI-H2869 GDSC2 6.0445 8.0588 2.6633 0.4604
NCI-H209 GDSC2 6.0504 8.1825 2.6206 0.5683
LC-1/sq GDSC2 6.0851 8.8331 2.3882 1.3067
ABC-1 GDSC2 6.139 8.2813 2.6194 0.5295
NCI-H740 GDSC2 6.1586 8.2208 2.6488 0.4478
NCI-H513 GDSC2 6.1706 8.1639 2.6737 0.3857
LB647-SCLC GDSC2 6.1937 7.9929 2.7422 0.2427
NCI-H211 GDSC2 6.2021 8.2775 2.6451 0.4389
NCI-H748 GDSC2 6.2079 7.9916 2.7477 0.2296
NCI-H727 GDSC2 6.2653 8.1685 2.7072 0.2859
NCI-H1944 GDSC2 6.268 8.5149 2.5848 0.56
EKVX GDSC2 6.2856 8.9004 2.4487 0.9506
Lu-99A GDSC2 6.2899 8.4389 2.6208 0.461
LC-2/ad GDSC2 6.3831 8.221 2.7314 0.2133
SW1573 GDSC2 6.4032 9.061 2.4371 0.9146
NCI-H2810 GDSC2 6.5206 8.5843 2.6554 0.3077
NCI-H1792 GDSC2 6.5515 8.3022 2.7627 0.1377
EMC-BAC-1 GDSC2 6.9446 9.2612 2.5743 0.3352
⏷ Show the Full List of 166 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 5.2502 7.5062 2.5346 1.4657
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OE33 GDSC2 4.1873 7.962 1.6776 8.1169
TE-1 GDSC2 4.8521 7.36 2.3905 2.6618
OE21 GDSC2 4.8944 6.9405 2.5942 1.5844
KYSE-410 GDSC2 5.2606 15.2542 -1.1157 19.7222
EC-GI-10 GDSC2 5.3141 7.4978 2.5682 1.2606
COLO 680N GDSC2 5.3426 7.0732 2.7463 0.5854
KYSE-510 GDSC2 5.3853 6.847 2.846 0.2937
KYSE-450 GDSC2 5.4524 13.6381 -0.1865 15.3048
TE-4 GDSC2 5.5365 7.3919 2.7065 0.594
TE-8 GDSC2 5.5945 8.73 2.1946 2.6488
KYSE-270 GDSC2 5.5967 7.7314 2.6029 0.8954
KYSE-180 GDSC2 5.6146 13.9465 -0.2222 15.1132
TE-5 GDSC2 5.6844 7.3651 2.7745 0.3421
TE-11 GDSC2 5.6874 7.5138 2.722 0.471
TE-6 GDSC2 5.7063 7.3779 2.7782 0.3253
TE-15 GDSC2 5.7365 7.8781 2.6062 0.7886
TE-9 GDSC2 5.8217 7.3352 2.8354 0.1811
KYSE-70 GDSC2 5.8916 8.4606 2.4483 1.2353
OE19 GDSC2 5.968 7.2153 2.9258 0.0536
KYSE-140 GDSC2 6.2079 8.6936 2.4945 0.8525
KYSE-520 GDSC2 6.2777 13.4687 0.4495 10.5467
TE-10 GDSC2 6.6046 8.3197 2.7751 0.116
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHOS-4 GDSC2 3.6977 6.3244 2.1212 6.5753
DOV13 GDSC2 3.9526 5.6812 2.6174 2.9257
A2780 GDSC2 4.0689 6.42 2.3425 4.3359
OVISE GDSC2 4.0914 5.9755 2.5685 2.9419
EFO-21 GDSC2 4.1704 10.8859 0.2217 16.4177
TYK-nu GDSC2 4.5264 6.4028 2.6317 1.8711
OAW42 GDSC2 4.6417 6.0498 2.8381 0.7718
OVTOKO GDSC2 4.7349 7.4275 2.2929 3.3728
ES-2 GDSC2 4.7827 9.1908 1.4975 7.8635
TOV-21G GDSC2 4.7921 6.4495 2.7472 1.0078
IGROV-1 GDSC2 4.8188 16.524 -2.0769 24.1889
OV56 GDSC2 4.8218 5.839 2.992 0.1785
OVK18 GDSC2 4.9811 6.8882 2.6584 1.201
JHOS-2 GDSC2 5.0294 6.4724 2.8428 0.4722
OVCAR-5 GDSC2 5.1951 8.7537 1.9628 4.4341
Caov-3 GDSC2 5.5545 7.0631 2.8329 0.2617
SK-OV-3 GDSC2 5.6697 7.3804 2.7634 0.3739
OAW28 GDSC2 5.6723 8.9206 2.1537 2.7499
EFO-27 GDSC2 5.7495 7.7441 2.662 0.6074
OVCAR-8 GDSC2 5.9296 7.8033 2.711 0.3929
OVCAR-4 GDSC2 6.0021 7.7664 2.7512 0.2812
OVCAR-3 GDSC2 6.013 7.5847 2.8178 0.1649
Kuramochi GDSC2 6.0473 16.1216 -0.9735 17.4184
TOV-112D GDSC2 6.1175 8.1471 2.6595 0.439
OV-90 GDSC2 6.7962 15.059 0.0344 11.5723
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HPAC GDSC2 4.1393 6.8059 2.2051 5.0169
KP-2 GDSC2 4.2191 5.8793 2.691 2.0185
CFPAC-1 GDSC2 4.3252 6.4665 2.4863 2.9867
PaTu 8988t GDSC2 4.479 9.4318 1.1694 10.4485
Panc 02.03 GDSC2 4.5232 9.1071 1.359 9.2409
SU.86.86 GDSC2 4.6378 6.2336 2.7615 1.1028
BxPC-3 GDSC2 4.7414 7.3914 2.3131 3.2508
Capan-2 GDSC2 4.7573 6.9659 2.5114 2.168
HuP-T3 GDSC2 4.7692 6.6047 2.6721 1.3649
QGP-1 GDSC2 4.7711 9.9237 1.1368 9.9663
DAN-G GDSC2 4.9275 10.6405 0.8989 10.9514
HPAF-II GDSC2 4.9332 7.1109 2.5419 1.7864
MIA PaCa-2 GDSC2 5.0003 7.5073 2.407 2.3671
KP-4 GDSC2 5.1384 6.7717 2.7751 0.6213
PSN1 GDSC2 5.2426 9.8086 1.5054 6.9013
YAPC GDSC2 5.2479 6.4621 2.9305 0.1674
PaTu 8902 GDSC2 5.4229 6.8499 2.8591 0.2516
SUIT-2 GDSC2 5.6132 7.0697 2.8521 0.2066
Panc 10.05 GDSC2 5.8798 8.9511 2.2452 2.0851
Panc 08.13 GDSC2 5.9076 7.8241 2.6951 0.4403
Capan-1 GDSC2 6.0311 8.003 2.6782 0.4297
KP-1N GDSC2 6.0527 8.2515 2.5962 0.6351
HuP-T4 GDSC2 6.0622 7.935 2.7142 0.3368
AsPC-1 GDSC2 6.0714 8.7382 2.4192 1.2025
PL4 GDSC2 6.28 8.0913 2.7392 0.2255
MZ-PC-1 GDSC2 6.4658 8.5748 2.6386 0.3575
KP-3 GDSC2 6.6738 8.6902 2.674 0.2357
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC2 5.1019 7.2145 2.5828 1.4074
NCI-H28 GDSC2 5.3384 8.316 2.2376 2.7671
MSTO-211H GDSC2 5.4969 7.6533 2.5896 1.019
NCI-H2052 GDSC2 5.817 7.5484 2.7593 0.3265
IST-Mes1 GDSC2 6.0249 8.0953 2.6424 0.5222
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H660 GDSC2 4.6718 6.3215 2.7417 1.155
LNCaP clone FGC GDSC2 4.8359 7.019 2.5304 1.9656
22Rv1 GDSC2 4.9003 8.4886 1.9056 5.2691
VCaP GDSC2 5.0406 6.7658 2.7349 0.8367
DU145 GDSC2 5.4327 7.4267 2.6496 0.8489
PC-3 GDSC2 5.4925 9.259 1.9077 4.2576
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 5.4193 7.7047 2.5339 1.3045
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-28 GDSC2 3.7663 5.6312 2.5134 3.9627
A101D GDSC2 3.9007 6.1935 2.3352 4.7517
RPMI-7951 GDSC2 4.0049 5.9538 2.5224 3.3869
WM793 GDSC2 4.0627 5.8321 2.6174 2.7107
LB373-MEL-D GDSC2 4.1207 6.3124 2.4285 3.7121
SK-MEL-3 GDSC2 4.1355 6.1355 2.5216 3.1328
COLO 679 GDSC2 4.3426 7.4474 2.0353 5.6069
IPC-298 GDSC2 4.4297 6.8342 2.3807 3.4035
GAK GDSC2 4.5383 6.7133 2.5006 2.5496
WM278 GDSC2 4.5609 7.4179 2.1914 4.2537
WM35 GDSC2 4.6428 7.6229 2.1472 4.357
G-361 GDSC2 4.6742 9.3096 1.3664 8.8597
CP50-MEL-B GDSC2 4.7281 6.6427 2.6352 1.5879
HT-144 GDSC2 4.7528 8.3494 1.8772 5.7122
Hs 938.T GDSC2 4.7765 6.1172 2.8715 0.5401
WM1552C GDSC2 4.8252 7.6196 2.2589 3.4123
MMAc-SF GDSC2 4.8275 6.8584 2.5948 1.6612
COLO 783 GDSC2 4.8969 6.2411 2.875 0.4508
SK-MEL-2 GDSC2 4.9217 6.206 2.8981 0.3682
SK-MEL-30 GDSC2 5.0094 6.3893 2.8656 0.4151
IGR-37 GDSC2 5.1011 11.0568 0.8181 11.0114
WM115 GDSC2 5.1131 6.3648 2.9149 0.2412
CP66-MEL GDSC2 5.132 6.3976 2.9104 0.2444
HMV-II GDSC2 5.1648 10.4469 1.1534 9.0287
SK-MEL-5 GDSC2 5.2064 6.4553 2.9177 0.2035
451Lu GDSC2 5.2134 7.0892 2.6848 0.8871
MZ-MEL-7 GDSC2 5.2204 7.0693 2.6957 0.8411
RVH-421 GDSC2 5.2332 6.7786 2.8116 0.4513
A-375 GDSC2 5.2657 7.4614 2.5603 1.34
UACC-62 GDSC2 5.2958 6.5334 2.9231 0.1674
Mel JuSo GDSC2 5.3356 7.0488 2.7526 0.5701
COLO 800 GDSC2 5.3389 7.4171 2.6119 1.0632
VMRC-MELG GDSC2 5.3443 6.6547 2.8986 0.1982
CHL-1 GDSC2 5.3464 7.2986 2.6617 0.8695
COLO 829 GDSC2 5.3785 7.5298 2.5851 1.1346
LB2518-MEL GDSC2 5.3786 6.7676 2.8717 0.2405
SH-4 GDSC2 5.3838 7.8235 2.4688 1.6164
Mel Ho GDSC2 5.3931 6.8574 2.8453 0.2924
SK-MEL-31 GDSC2 5.4718 6.912 2.8554 0.243
WT2-iPS GDSC2 5.4759 6.6909 2.933 0.1118
G-mel GDSC2 5.5239 7.1535 2.789 0.3728
UACC-257 GDSC2 5.524 6.9703 2.8542 0.2288
A-431 GDSC2 5.5308 7.5457 2.646 0.7923
COLO 792 GDSC2 5.6337 8.3202 2.3855 1.7243
LOX-IMVI GDSC2 5.641 7.3361 2.7683 0.374
Hs 940.T GDSC2 5.7116 7.2191 2.8359 0.2083
M14 GDSC2 5.7313 7.452 2.7612 0.3544
A-388 GDSC2 5.7426 8.2125 2.4793 1.2387
MZ-MEL-2 GDSC2 5.7546 7.97 2.5789 0.8679
IGR-1 GDSC2 5.8019 7.3226 2.8326 0.1904
DJM-1 GDSC2 5.8136 7.5167 2.7693 0.3063
A2058 GDSC2 7.4244 24.3519 -4.0011 24.167
SK-MEL-24 GDSC2 7.6145 15.9474 0.1263 9.7596
EquiPSC Line K2 GDSC2 5.4118 8.3095 2.2791 2.4667
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 4.4112 7.1325 2.23 4.3124
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-402 GDSC2 4.3745 6.7206 2.3992 3.3974
MES-SA GDSC2 4.473 6.1015 2.7337 1.4273
Rh30 GDSC2 4.6622 6.5237 2.6518 1.5894
TE 441.T GDSC2 4.6843 6.1316 2.825 0.7868
VA-ES-BJ GDSC2 4.7711 6.6968 2.6344 1.5401
SW982 GDSC2 4.7731 9.0158 1.5747 7.4345
SW684 GDSC2 4.7756 8.1829 1.9697 5.1333
GCT GDSC2 4.8304 9.3949 1.432 8.1428
RKN GDSC2 5.0663 6.5427 2.8316 0.485
RD GDSC2 5.1026 8.2996 2.1138 3.7597
HT-1080 GDSC2 5.2144 6.6584 2.8482 0.3603
EW-8 GDSC2 5.3986 6.8739 2.8414 0.299
KYM-1 GDSC2 5.4226 6.8044 2.875 0.2198
SK-UT-1 GDSC2 5.566 7.6577 2.618 0.8642
SK-LMS-1 GDSC2 5.579 7.3769 2.7292 0.5048
SW872 GDSC2 5.8299 8.2559 2.5011 1.0876
G-401 GDSC2 5.8771 8.2572 2.5211 0.9817
Rh41 GDSC2 6.2791 7.5746 2.9113 0.0391
A-204 GDSC2 6.3347 9.1523 2.3733 1.1724
STS-0421 GDSC2 6.6225 8.9965 2.5479 0.4992
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCH GDSC2 4.1253 7.4658 1.8754 7.0575
23132/87 GDSC2 4.1869 8.2241 1.549 8.8963
RERF-GC-1B GDSC2 4.5413 11.1443 0.3746 14.6806
MKN45 GDSC2 4.738 5.7582 2.9892 0.2156
AGS GDSC2 4.8094 11.5104 0.3914 13.9435
GCIY GDSC2 4.8356 7.6175 2.266 3.3568
ECC12 GDSC2 4.8415 6.8121 2.6214 1.518
OCUM-1 GDSC2 4.8577 7.4264 2.3641 2.7927
TMK-1 GDSC2 4.927 7.9329 2.1769 3.6975
IM95 GDSC2 5.1899 7.1974 2.6313 1.116
NUGC-4 GDSC2 5.2365 7.4968 2.5318 1.492
Hs 746.T GDSC2 5.2882 6.8628 2.8025 0.4483
SK-GT-2 GDSC2 5.2885 7.4234 2.5863 1.2099
ECC10 GDSC2 5.354 7.3625 2.6401 0.9431
MKN1 GDSC2 5.3615 6.7486 2.872 0.2456
NUGC-3 GDSC2 5.4615 7.1553 2.7639 0.4677
RF-48 GDSC2 5.5827 7.7095 2.6053 0.8971
SNU-1 GDSC2 5.6278 7.551 2.6844 0.6087
SNU-5 GDSC2 5.7076 7.2988 2.8067 0.2647
MKN7 GDSC2 5.76 7.7043 2.6809 0.5475
HGC-27 GDSC2 5.7902 7.3491 2.8193 0.2162
KATO III GDSC2 5.9917 8.3241 2.5441 0.8281
NCI-N87 GDSC2 6.1449 8.3299 2.604 0.5673
MKN28 GDSC2 6.5698 9.718 2.2564 1.4165
SNG-M GDSC2 5.6287 7.6718 2.6393 0.7498
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
B-CPAP GDSC2 4.1913 6.4061 2.4302 3.5617
8505C GDSC2 4.458 8.8339 1.4458 8.8787
BHT-101 GDSC2 4.9572 10.6649 0.9077 10.8367
CAL-62 GDSC2 5.2274 6.5408 2.8954 0.2426
IHH-4 GDSC2 5.305 6.8103 2.8284 0.3702
ASH-3 GDSC2 5.3106 6.978 2.7688 0.5348
WRO GDSC2 5.3533 11.886 0.5917 11.6733
FTC-133 GDSC2 5.4417 7.1464 2.7593 0.4908
HTC-C3 GDSC2 5.6076 7.8605 2.5575 1.0517
8305C GDSC2 5.6759 7.028 2.8887 0.1333
KMH-2 GDSC2 5.6868 7.5862 2.6952 0.545
ML-1 [Human leukemia] GDSC2 5.808 7.7938 2.6671 0.5616
TT2609-C02 GDSC2 6.1172 7.9071 2.7442 0.2603
K5 GDSC2 6.3225 8.0341 2.7738 0.1643
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Detroit 562 GDSC2 3.9638 6.7298 2.1188 5.9393
SAS GDSC2 4.196 7.6452 1.8383 7.1207
CAL-27 GDSC2 4.2372 5.9292 2.679 2.0549
SCC-9 GDSC2 4.444 8.6566 1.522 8.4588
BICR 10 GDSC2 4.4876 6.6242 2.5114 2.5717
NCI-H3118 GDSC2 4.5246 6.8634 2.4247 2.9901
SCC-4 GDSC2 4.631 6.8753 2.4812 2.511
SCC-15 GDSC2 4.7197 6.8734 2.5313 2.1179
LB771-HNC GDSC2 4.764 7.9431 2.074 4.5557
HSC-2 GDSC2 4.7694 6.4258 2.7461 1.0349
PCI-15A GDSC2 4.81 7.1584 2.4559 2.3805
BB49-HNC GDSC2 4.9858 14.1414 -0.7715 18.9726
DOK GDSC2 4.9938 7.5933 2.366 2.5855
UPCI-SCC-090 GDSC2 5.0441 7.822 2.2932 2.8918
FaDu GDSC2 5.1314 10.5293 1.0918 9.441
HSC-3 GDSC2 5.1708 6.7752 2.7873 0.5605
KON GDSC2 5.1961 8.1211 2.2456 2.9218
OSC-19 GDSC2 5.2824 12.5119 0.2405 13.6252
HO-1-N-1 GDSC2 5.2854 6.9068 2.7851 0.5004
BHY GDSC2 5.4487 7.1681 2.7541 0.502
KOSC-2 GDSC2 5.5575 8.1834 2.4049 1.7175
PE/CA-PJ15 GDSC2 5.5636 7.5987 2.6397 0.7915
BICR 22 GDSC2 5.5951 7.1429 2.8198 0.2751
CAL-33 GDSC2 5.6064 7.5263 2.6848 0.6195
HSC-4 GDSC2 5.6081 7.0461 2.8584 0.1967
SAT [Human HNSCC] GDSC2 5.7418 9.2479 2.0497 3.1707
SCC-25 GDSC2 5.7563 7.3651 2.8013 0.2598
BICR 31 GDSC2 5.8524 7.7375 2.7051 0.4394
SKN-3 GDSC2 5.8723 10.5581 1.5434 5.5944
Ca9-22 GDSC2 5.888 7.663 2.7453 0.3314
JHU-011 GDSC2 5.9113 8.0933 2.5976 0.7088
JHU-022 GDSC2 5.9982 15.3306 -0.6248 16.0772
JHU-029 GDSC2 6.0277 9.3143 2.1674 2.2742
BICR 78 GDSC2 6.0567 7.9465 2.7081 0.3518
BB30-HNC GDSC2 6.0782 8.4049 2.5494 0.7592
OSC-20 GDSC2 6.0991 7.7539 2.7905 0.1869
PCI-06A GDSC2 6.1548 7.9244 2.7518 0.2363
PCI-04B GDSC2 6.6504 8.7136 2.6576 0.2682
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1710 GDSC2 4.236 7.4924 1.9406 6.4088
TCCSUP GDSC2 4.2828 7.0526 2.1838 4.8425
KU-19-19 GDSC2 4.3862 10.4557 0.5985 13.8787
BFTC-905 GDSC2 4.7156 6.7403 2.5869 1.8415
CAL-29 GDSC2 4.8723 7.093 2.5179 1.9807
SW780 GDSC2 4.9059 12.8218 -0.1813 16.5419
639V GDSC2 4.9945 5.9275 3.0235 0.0822
647V GDSC2 5.123 7.0909 2.6431 1.1289
RT-112 GDSC2 5.1408 10.4735 1.1248 9.2377
HT-1197 GDSC2 5.2072 6.8318 2.7811 0.5578
RT-4 GDSC2 5.2521 8.7325 2.0056 4.1088
J82 GDSC2 5.5778 9.3252 1.9265 4.0292
5637 GDSC2 5.7228 7.5609 2.7187 0.4629
T24 GDSC2 6.3758 8.2718 2.7114 0.2479
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PA-1 GDSC2 3.8901 5.9203 2.4604 4.0077
CAL-39 GDSC2 3.9514 6.602 2.1723 5.6379
PWR-1E GDSC2 4.0032 5.9732 2.512 3.4527
NEC8 GDSC2 4.0784 5.8969 2.5971 2.7997
SiHa GDSC2 4.2732 8.2704 1.5887 8.4526
HeLa GDSC2 4.2734 6.5214 2.4286 3.4142
C-4-I GDSC2 4.453 7.0886 2.2771 3.9581
SKG-IIIa GDSC2 4.5152 9.8237 1.004 11.3114
JEG-3 GDSC2 4.8922 8.8676 1.7231 6.3336
ACC-OV7 GDSC2 5.0055 7.677 2.3357 2.7257
SiSo GDSC2 5.0724 10.277 1.1729 9.1115
MS751 GDSC2 5.1006 7.5383 2.4466 2.0411
OVCA433 GDSC2 5.1047 9.8007 1.4206 7.6468
OVCA420 GDSC2 5.1179 7.3974 2.5148 1.6974
ME-180 GDSC2 5.127 7.4891 2.4809 1.8451
OVMIU GDSC2 5.1786 7.487 2.5076 1.6623
BPH-1 GDSC2 5.1839 10.3972 1.1897 8.7869
JAR GDSC2 5.3359 6.7743 2.8533 0.2962
SKN GDSC2 5.3744 8.506 2.1745 3.0377
OMC-1 [Human cervical carcinoma] GDSC2 5.4182 7.2546 2.7092 0.6566
DoTc2 4510 GDSC2 5.5048 7.2143 2.7595 0.4584
SW962 GDSC2 5.5075 7.2944 2.731 0.5373
HEY GDSC2 5.5503 8.0772 2.4448 1.5528
LB831-BLC GDSC2 5.6131 13.226 0.1248 13.4743
DSH1 GDSC2 5.6374 7.8246 2.5845 0.9309
HEC-1 GDSC2 5.7527 7.2988 2.8232 0.2197
JHOS-3 GDSC2 5.7899 7.5835 2.7365 0.3891
OV17R GDSC2 5.8556 8.0773 2.5806 0.7959
TC-YIK GDSC2 5.868 8.5936 2.3849 1.5033
SW756 GDSC2 5.9202 18.3861 -2.1698 22.0048
Ca Ski GDSC2 5.9294 8.4273 2.478 1.0964
HT-3 GDSC2 6.045 8.0674 2.6604 0.4673
SW954 GDSC2 6.109 8.1664 2.6493 0.4671
C-33 A GDSC2 6.2673 8.1843 2.7024 0.2943
PEO1 GDSC2 6.3126 8.4441 2.6275 0.4362
UWB1.289 GDSC2 6.912 9.4102 2.5099 0.4751
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug

References

1 A selective inhibitor reveals PI3Kgamma dependence of T(H)17 cell differentiation. Nat Chem Biol. 2012 Apr 29;8(6):576-82.