Details of the Drug

General Information of Drug (ID: DMLC7HE)

Drug Name
A804598
Synonyms A-804598; A 804598
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 315.4
Logarithm of the Partition Coefficient (xlogp) 4
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C19H17N5
IUPAC Name
1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine
Canonical SMILES
C[C@@H](C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3
InChI
InChI=1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1
InChIKey
PQYCRDPLPKGSME-AWEZNQCLSA-N
Cross-matching ID
PubChem CID
53325874
TTD ID
D0Q1PO

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
P2X purinoceptor 7 (P2RX7) TT473XN P2RX7_HUMAN Antagonist [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
P2X purinoceptor 7 (P2RX7) DTT P2RX7 3.17E-01 -0.1 -0.22
P2X purinoceptor 7 (P2RX7) DTT P2RX7 5.97E-02 0.16 0.37
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 95 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 6.9405 8.6524 5.3899 1.5334
JK1 CTRP2 7.1999 14.3921 2.7901 11.4487
JM1 CTRP2 8.0659 9.6114 5.5373 0.2574
MOLM-16 CTRP2 6.0695 8.426 4.8744 4.8697
LP-1 CTRP2 6.2991 7.9906 5.2745 2.7765
SET-2 CTRP2 6.4347 8.7796 4.9869 3.7462
MOLT-16 CTRP2 6.4713 8.0587 5.367 2.1212
OCI-Ly3 CTRP2 6.4971 8.6698 5.0872 3.2294
HEL 92.1.7 CTRP2 6.5757 8.3072 5.3194 2.322
TF-1 CTRP2 6.6083 10.0828 4.4737 6.0035
RL CTRP2 6.6135 7.9082 5.5333 1.2663
ST486 CTRP2 6.6291 8.7908 5.1227 2.8809
L-540 CTRP2 6.668 9.0455 5.0264 3.2148
BV-173 CTRP2 6.7223 8.9543 5.1083 2.8029
CMK CTRP2 6.771 8.8131 5.2087 2.3329
Kasumi-1 CTRP2 6.771 9.1524 5.0463 2.9829
K-562 CTRP2 6.7871 8.8708 5.1919 2.554
SUP-B15 CTRP2 6.8614 8.8634 5.2437 2.0768
L-428 CTRP2 6.9147 8.8746 5.2721 1.9007
F-36P CTRP2 6.925 8.8621 5.2843 1.8416
KO52 CTRP2 6.9268 10.6812 4.4139 5.7192
SUP-T1 CTRP2 6.9528 8.8347 5.314 1.6963
KMS-34 CTRP2 7.0359 8.5826 5.4753 1.0258
DB CTRP2 7.0615 9.3894 5.1244 2.2881
HPB-ALL CTRP2 7.0658 8.9621 5.3233 1.5358
MC116 CTRP2 7.0986 15.1841 2.3206 13.4224
HD-MY-Z CTRP2 7.0988 10.0314 4.8463 3.3274
HL-60 CTRP2 7.1453 8.8284 5.4274 1.1685
Ci-1 CTRP2 7.1656 8.0645 5.7478 0.1705
Mino CTRP2 7.1676 8.5624 5.5525 0.6655
MOLM-6 CTRP2 7.1712 10.388 4.7247 3.7121
EJM CTRP2 7.1798 13.9392 2.9987 10.6635
SUP-HD1 CTRP2 7.1977 10.2437 4.8106 3.3367
M-07e CTRP2 7.2012 8.9944 5.3854 1.1799
SU-DHL-6 CTRP2 7.2014 11.2636 4.3248 5.2747
SR CTRP2 7.2059 11.9689 3.9855 6.645
AMO1 CTRP2 7.2308 10.1124 4.8937 2.969
SU-DHL-8 CTRP2 7.2335 9.2134 5.3068 1.4218
JeKo-1 CTRP2 7.246 10.8172 4.5698 4.226
BL-70 CTRP2 7.3079 8.5241 5.6332 0.3847
Kasumi-2 CTRP2 7.3632 13.4955 3.3526 8.956
Karpas-422 CTRP2 7.391 9.0673 5.4529 0.8031
RPMI-8226 CTRP2 7.408 9.3613 5.3371 1.1568
SKM-1 CTRP2 7.4311 8.7324 5.6061 0.3623
OCI-Ly19 CTRP2 7.433 11.2661 4.4803 4.3266
A4/Fukuda CTRP2 7.4406 9.0692 5.4763 0.7506
NU-DHL-1 CTRP2 7.4529 9.8408 5.1517 1.7513
OCI-AML-5 CTRP2 7.4689 8.5225 5.6999 0.1597
MHH-CALL-4 CTRP2 7.469 15.4809 2.4544 12.2871
P3HR-1 CTRP2 7.4905 9.4719 5.3329 1.1012
Pfeiffer CTRP2 7.4988 9.1613 5.4665 0.6881
Granta-519 CTRP2 7.5279 11.1565 4.5936 3.7584
TALL-1 [Human adult T-ALL] CTRP2 7.5448 12.2549 4.0831 5.7517
SIG-M5 CTRP2 7.545 8.5765 5.7095 0.1347
U-937 CTRP2 7.5527 9.3378 5.4202 0.7857
SU-DHL-10 CTRP2 7.5936 8.525 5.7451 0.0722
OPM-2 CTRP2 7.7115 8.9056 5.6552 0.1647
Ri-1 CTRP2 7.7136 10.0079 5.2201 1.281
OCI-Ly10 CTRP2 7.7209 11.1861 4.7 3.1168
SU-DHL-4 CTRP2 7.7317 13.5938 3.5666 7.54
MOTN-1 CTRP2 7.8075 9.5522 5.452 0.5452
AML-193 CTRP2 7.8104 8.8757 5.702 0.0835
GA-10 CTRP2 7.8179 8.8599 5.7101 0.0742
DND-41 CTRP2 7.8477 10.7336 4.9773 1.976
L-363 CTRP2 7.8586 9.2786 5.5772 0.2524
HuT 78 CTRP2 7.864 10.7875 4.9626 2.0113
OCI-AML-3 CTRP2 7.8641 9.2157 5.6022 0.2074
Karpas-620 CTRP2 7.906 9.4096 5.5479 0.2907
MOLP-8 CTRP2 7.9319 9.2599 5.6123 0.1735
SUP-T11 CTRP2 7.9336 9.8326 5.3981 0.6132
KMS-12-BM CTRP2 7.9401 9.4022 5.5642 0.2496
Hs 611.T CTRP2 7.9849 10.0945 5.3173 0.7958
Daudi CTRP2 7.9872 9.3723 5.5932 0.1883
JJN-3 CTRP2 8.0471 9.504 5.5688 0.2104
NU-DUL-1 CTRP2 8.0602 9.4103 5.607 0.1511
SEM CTRP2 8.0781 9.2224 5.6782 0.0692
MM1.S CTRP2 8.1073 10.941 5.0264 1.5806
KMS-20 CTRP2 8.137 10.1846 5.3504 0.6248
U266B1 CTRP2 8.2476 9.7324 5.5631 0.1696
OCI-M1 CTRP2 8.2574 9.3599 5.6936 0.0434
PL21 CTRP2 8.2575 9.7249 5.5694 0.159
RS4;11 CTRP2 8.296 10.5783 5.2666 0.7498
THP-1 CTRP2 8.3102 9.7869 5.5671 0.1512
MOLP-2 CTRP2 8.4636 10.1947 5.4802 0.238
KYO-1 CTRP2 8.4745 9.5547 5.7019 0.0233
ME1 CTRP2 8.5161 10.3217 5.4548 0.2639
RCH-ACV CTRP2 8.5621 10.3488 5.4626 0.2396
RPMI-6666 CTRP2 8.5753 9.9348 5.6104 0.0684
KMS-18 CTRP2 8.646 10.2088 5.5423 0.1206
EB1 CTRP2 8.7029 10.4312 5.4859 0.1755
KMS-11 CTRP2 8.7676 11.0581 5.2843 0.4917
Mono-Mac-1 CTRP2 8.893 11.0322 5.3438 0.3387
MHH-CALL-3 CTRP2 8.8973 18.2549 2.122 11.3014
KMS-28BM CTRP2 8.9632 11.176 5.319 0.36
REC-1 CTRP2 8.9969 10.8128 5.46 0.1525
⏷ Show the Full List of 95 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 7.7064 13.5396 3.5752 7.5427
TE8 CTRP2 8.1133 18.251 1.5677 14.4312
KYSE-450 CTRP2 6.8547 9.0295 5.1611 2.4092
TE-5 CTRP2 6.982 17.4571 1.0993 17.945
KYSE-510 CTRP2 6.9833 8.9792 5.2661 1.8417
KYSE-30 CTRP2 7.0315 8.5467 5.4885 0.9846
TE-11 CTRP2 7.3323 12.1403 3.9916 6.8996
KYSE-410 CTRP2 7.6017 10.6172 4.8886 2.5487
OE21 CTRP2 7.7033 10.6628 4.9273 2.2976
TE-14 CTRP2 7.8603 10.3695 5.142 1.4116
KYSE-520 CTRP2 7.888 11.0412 4.8637 2.3356
OE19 CTRP2 7.9259 9.3295 5.585 0.2182
TE-4 CTRP2 7.9971 13.367 3.8547 6.0314
TE-1 CTRP2 8.0122 10.2004 5.2874 0.8614
KYSE-150 CTRP2 8.1303 9.8408 5.4786 0.3441
KYSE-70 CTRP2 8.455 10.0441 5.5303 0.1689
TE-6 CTRP2 8.5983 19.1498 1.479 13.9715
EC-GI-10 CTRP2 9.9359 19.005 2.4489 8.7652
OE33 CTRP2 10.9244 28.3862 -1.3673 18.7348
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.0337 9.1347 5.2252 1.937
PSN1 CTRP2 7.069 9.3904 5.1287 2.2626
Panc 03.27 CTRP2 7.103 8.7117 5.4554 1.0315
KP-2 CTRP2 7.1601 9.2564 5.2454 1.7189
PK-45H CTRP2 7.3085 18.2994 0.9359 17.8903
Panc 04.03 CTRP2 7.3232 10.0934 4.9604 2.7915
SW1990 CTRP2 7.3799 12.0498 4.0687 6.047
Panc 10.05 CTRP2 7.7897 9.8155 5.3384 0.8618
PaTu 8988t CTRP2 7.8026 8.9963 5.6573 0.1395
MIA PaCa-2 CTRP2 7.8888 9.0395 5.6737 0.1091
HPAC CTRP2 7.9063 10.1751 5.2469 1.0493
PaTu 8902 CTRP2 7.985 9.1288 5.6773 0.0824
YAPC CTRP2 8.0105 9.0671 5.7071 0.0533
DAN-G CTRP2 8.0269 9.4394 5.5842 0.1917
SNU-410 CTRP2 8.0392 9.9873 5.3843 0.592
TCC-Pan2 CTRP2 8.0416 9.6017 5.5312 0.2758
Panc 05.04 CTRP2 8.0486 9.4398 5.5923 0.1744
Panc 02.03 CTRP2 8.0768 11.2275 4.8864 2.0731
AsPC-1 CTRP2 8.0792 10.5932 5.1586 1.1896
SU.86.86 CTRP2 8.1283 24.8506 -1.6835 23.5771
Hs 766T CTRP2 8.1823 13.7389 3.7996 5.9998
PaTu 8988s CTRP2 8.3062 9.9591 5.5046 0.242
HuP-T3 CTRP2 8.3443 12.0255 4.6833 2.7071
Panc 08.13 CTRP2 8.3544 10.4169 5.3545 0.5122
Capan-2 CTRP2 8.362 10.0577 5.4905 0.2491
L3.3 CTRP2 8.4762 14.7169 3.5287 6.6579
PK-59 CTRP2 8.7581 10.7917 5.3785 0.3201
HuP-T4 CTRP2 8.8996 10.5513 5.515 0.111
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.9124 23.0234 -2.5554 29.2423
CJM [Human melanoma] CTRP2 6.6758 10.6535 4.2426 6.4367
WM266-4 CTRP2 6.7338 8.5044 5.3305 2.0426
Hs 940.T CTRP2 6.9142 10.958 4.2694 5.9382
SK-MEL-28 CTRP2 6.9521 7.9077 5.7168 0.3388
WM88 CTRP2 7.0203 9.4189 5.0846 2.4937
UACC-257 CTRP2 7.1531 9.2229 5.2564 1.6861
UACC-62 CTRP2 7.1619 8.2941 5.6585 0.3717
HMCB CTRP2 7.1733 8.6679 5.5111 0.789
WM115 CTRP2 7.1887 10.2377 4.8076 3.6094
SK-MEL-2 CTRP2 7.235 8.777 5.4964 0.7871
IGR-39 CTRP2 7.2712 9.0273 5.4086 1.039
WT2-iPS CTRP2 7.3933 9.9553 5.0659 2.124
HT-144 CTRP2 7.4076 9.8109 5.1393 1.8419
A2058 CTRP2 7.4648 8.5249 5.6974 0.165
Hs 936.T CTRP2 7.479 8.5553 5.6919 0.17
RVH-421 CTRP2 7.4939 10.1292 5.0461 2.088
LOX-IMVI CTRP2 7.607 11.8309 4.3268 4.6997
Hs 895.T CTRP2 7.643 8.9305 5.6194 0.2654
IGR-1 CTRP2 7.6456 13.0481 3.7705 6.8549
Hs 688(A).T CTRP2 7.6691 8.8956 5.6425 0.1971
IGR-37 CTRP2 7.7394 8.7876 5.7069 0.0898
SK-MEL-30 CTRP2 7.7507 9.3788 5.4947 0.4704
MeWo CTRP2 7.8827 10.8981 4.9242 2.2851
MDA-MB-435S CTRP2 7.9058 9.3816 5.5581 0.2716
IPC-298 CTRP2 7.929 8.987 5.7059 0.0634
A101D CTRP2 7.9336 9.0482 5.6867 0.0806
SK-MEL-5 CTRP2 7.975 9.5781 5.5132 0.3331
Mel JuSo CTRP2 8.0641 10.0173 5.3835 0.5812
K029AX CTRP2 8.0813 9.9498 5.417 0.4943
COLO 792 CTRP2 8.0948 15.5935 2.8519 9.7877
COLO 800 CTRP2 8.0972 9.8324 5.4682 0.3771
Hs 852.T CTRP2 8.1205 9.6997 5.5265 0.2593
Hs 294T CTRP2 8.1628 9.2514 5.6976 0.0456
G-361 CTRP2 8.233 9.6303 5.5935 0.1335
Malme-3M CTRP2 8.233 10.8674 5.1204 1.1935
SK-MEL-3 CTRP2 8.2797 9.5905 5.6239 0.0927
COLO 829 CTRP2 8.2878 9.9404 5.5042 0.2476
WM793 CTRP2 8.2996 9.6104 5.6241 0.0897
WM1799 CTRP2 8.3202 9.4902 5.6716 0.0491
A-375 CTRP2 8.3353 9.7022 5.6054 0.103
SK-MEL-31 CTRP2 8.3935 9.6291 5.6503 0.057
Hs 944.T CTRP2 8.6246 10.6714 5.37 0.3773
WM983B CTRP2 9.7163 16.4926 3.4703 5.4063
Hs 839.T CTRP2 11.5571 23.5476 1.349 10.4535
Hs 934.T CTRP2 11.5655 33.76 -3.5252 22.4526
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 6.9975 13.7586 2.9499 11.1656
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Kelly CTRP2 7.2921 9.2847 5.3079 1.3608
NH-6 CTRP2 7.3274 12.2503 3.9348 7.1533
KP-N-YN CTRP2 7.3348 9.2456 5.3482 1.184
SK-N-FI CTRP2 7.4382 12.2512 4.0118 6.6443
IMR-32 CTRP2 7.7512 8.7111 5.7372 0.0622
NB1 CTRP2 7.8704 10.5906 5.0522 1.6994
CHP-126 CTRP2 7.8832 10.4089 5.137 1.4089
SK-N-DZ CTRP2 7.9397 16.2877 2.4035 12.4868
SK-N-SH CTRP2 8.1012 10.0259 5.3963 0.5327
SK-N-BE(2) CTRP2 8.5068 10.1366 5.517 0.1755
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-869 CTRP2 8.4443 10.196 5.4724 0.2555
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-MC CTRP2 6.5036 7.97 5.4322 1.8104
TC71 CTRP2 6.526 11.4753 3.7192 8.8674
HOS CTRP2 6.6269 9.2361 4.9041 3.7791
Hs 822.T CTRP2 7.1802 8.2483 5.6845 0.2989
A-673 CTRP2 7.3817 8.7137 5.5917 0.4533
SK-ES-1 CTRP2 7.4877 9.2193 5.4374 0.7802
SaOS-2 CTRP2 7.518 10.4443 4.9174 2.5352
Hs 888.T CTRP2 8.0102 10.177 5.2958 0.8391
SJSA-1 CTRP2 8.086 10.0404 5.3841 0.5688
G-292 clone A141B1 CTRP2 8.1566 10.0753 5.4011 0.4962
CAL-78 CTRP2 8.5185 10.1785 5.5066 0.1869
MG-63 CTRP2 9.7247 20.8672 1.4304 12.4986
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 60 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-453 CTRP2 6.395 10.1973 4.2524 6.8806
DU4475 CTRP2 6.6199 8.5615 5.2272 2.47
ZR-75-30 CTRP2 6.7729 12.1697 3.5657 9.0678
HCC1500 CTRP2 6.8313 10.7362 4.3176 5.872
MDA-MB-157 CTRP2 7.0648 9.4241 5.1103 2.3383
HCC1428 CTRP2 7.1323 9.165 5.2705 1.6571
HCC202 CTRP2 7.1467 10.5587 4.6267 4.137
HCC1419 CTRP2 7.2282 17.8234 1.1101 17.4668
Hs 578T CTRP2 7.3262 14.5736 2.7952 11.2174
Hs 578Bst CTRP2 7.3885 11.7089 4.2389 5.3502
MDA-MB-468 CTRP2 7.4022 11.3749 4.4081 4.6548
EFM-192A CTRP2 7.4396 9.8463 5.1417 1.8002
MDA-MB-361 CTRP2 7.5266 9.9219 5.1571 1.6598
HCC2218 CTRP2 7.7116 9.6341 5.3751 0.8084
HCC38 CTRP2 7.7429 10.7348 4.9178 2.2906
MDA-MB-415 CTRP2 7.7433 10.7327 4.919 2.2859
MDA-MB-231 CTRP2 7.8435 10.005 5.2865 0.9761
T-47D CTRP2 7.8572 14.0462 3.4349 7.8764
SK-BR-3 CTRP2 7.8671 9.5751 5.4692 0.474
BT-474 CTRP2 7.8759 9.299 5.5766 0.2479
ZR-75-1 CTRP2 7.9872 9.2254 5.6449 0.1176
BT-20 CTRP2 8.206 10.0339 5.4374 0.4272
AU565 CTRP2 8.3235 11.4191 4.9346 1.6984
HCC1143 CTRP2 8.6349 14.5657 3.7005 5.8047
CAL-85-1 CTRP2 8.8316 11.7686 5.0373 1.0431
BT-549 CTRP2 10.1735 21.813 1.2788 12.3838
CAL-51 CTRP2 14.4624 30.7027 -0.1764 11.6507
BT 428 CTRP2 6.2692 9.2659 4.6169 5.58
BT 498 CTRP2 6.7089 17.962 0.6299 19.9462
BT 416 CTRP2 6.725 10.4233 4.393 5.7323
BT 145 CTRP2 6.7501 8.4154 5.3827 1.6776
BT 248 CTRP2 6.9449 9.1613 5.1572 2.3071
BT 112 CTRP2 6.9965 11.9232 3.8558 7.5049
BT 224 CTRP2 7.1263 8.9761 5.3518 1.3696
BT 422 CTRP2 7.1801 8.3331 5.6514 0.38
BT164 CTRP2 7.2422 8.6105 5.5689 0.5657
BT 504 CTRP2 7.3352 8.8958 5.4966 0.7123
BT 444 CTRP2 7.3522 9.6995 5.1574 1.8342
BT 333 CTRP2 7.3902 8.7078 5.5978 0.4025
BT 179 CTRP2 7.3985 11.4243 4.3821 4.7637
BT 320 CTRP2 7.4154 8.5473 5.6696 0.2318
BT 159 CTRP2 7.43 8.9891 5.5039 0.6272
BT 286 CTRP2 7.4808 9.3016 5.3999 0.8982
BT 359 CTRP2 7.488 9.3543 5.3814 0.9499
BT 216 CTRP2 7.5675 16.936 1.81 14.4846
BT 232 CTRP2 7.595 11.6908 4.3853 4.4857
BT 330 CTRP2 7.6133 9.1178 5.536 0.4394
BT 328 CTRP2 7.6937 9.3204 5.4924 0.5048
BT 239 CTRP2 7.7269 9.2981 5.5155 0.4328
BT 231 CTRP2 7.7455 11.7675 4.4458 4.0568
BT 172 CTRP2 7.7458 10.4097 5.0635 1.775
BT 245 CTRP2 7.791 9.7263 5.3752 0.7568
BT 440 CTRP2 7.8475 9.046 5.6564 0.1309
BT 139 CTRP2 7.8738 9.1656 5.6239 0.1706
BT 131 CTRP2 7.9746 9.3152 5.6087 0.1683
BT 271 CTRP2 8.0018 9.5834 5.5221 0.3062
BT 340 CTRP2 8.0077 9.3014 5.6259 0.1373
BT 482 CTRP2 8.1282 9.6259 5.5561 0.2086
BT 228 CTRP2 8.254 9.5778 5.6191 0.1012
BT147 CTRP2 8.8958 17.4018 2.5303 9.8349
⏷ Show the Full List of 60 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CCF-STTG1 CTRP2 7.0311 9.0886 5.2448 1.8661
T98G CTRP2 7.0553 9.5037 5.0672 2.5172
Becker CTRP2 7.147 8.9111 5.3921 1.2076
YH-13 CTRP2 7.179 9.1909 5.2859 1.5517
Hs 683 CTRP2 7.3263 9.7076 5.1387 2.073
42-MG-BA CTRP2 7.4331 13.6564 3.3245 8.9572
TM-31 CTRP2 7.5024 12.6833 3.8475 6.7566
DK-MG CTRP2 7.5107 9.191 5.4601 0.6987
SF268 CTRP2 7.5557 10.4232 4.9494 2.3748
SF539 CTRP2 7.6941 12.7201 3.9612 6.0272
GOS-3 CTRP2 7.7045 11.1234 4.7188 3.0652
M059K CTRP2 7.8582 9.4125 5.5273 0.3496
GaMG CTRP2 7.9257 9.3991 5.5596 0.2623
KG-1-C CTRP2 7.9305 9.089 5.6716 0.0969
GMS-10 CTRP2 7.9613 8.9702 5.7226 0.0467
SW1088 CTRP2 7.9625 9.5805 5.5072 0.3499
A-172 CTRP2 7.9804 10.7582 5.0383 1.6488
U-118MG CTRP2 8.0095 9.7197 5.4744 0.3994
DBTRG-05MG CTRP2 8.0607 9.7163 5.4966 0.3342
U-251MG CTRP2 8.1009 9.6227 5.5468 0.231
KALS-1 CTRP2 8.1254 11.7274 4.6926 2.7043
8-MG-BA CTRP2 8.1855 13.9596 3.6974 6.3916
SW1783 CTRP2 8.3219 10.5167 5.3022 0.6481
SNB-75 CTRP2 8.4581 12.336 4.6095 2.6674
KNS-60 CTRP2 9.9336 23.2962 0.4052 15.3935
KNS-81 CTRP2 10.0508 24.0062 0.1435 15.9869
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EN CTRP2 6.183 8.0032 5.1779 3.3833
JHUEM-1 CTRP2 6.4517 7.8917 5.4342 2.0162
HEC-1-A CTRP2 6.6299 9.2259 4.9113 3.7447
HEC-151 CTRP2 7.0136 8.7659 5.3813 1.3803
JHUEM-7 CTRP2 7.4523 9.6489 5.2361 1.4573
MFE-319 CTRP2 7.5078 8.8882 5.579 0.3889
ESS-1 CTRP2 7.5662 9.1562 5.4999 0.5553
AN3-CA CTRP2 7.6401 11.3794 4.5605 3.7455
MFE-296 CTRP2 7.715 10.7772 4.8827 2.4471
JHUEM-3 CTRP2 8.0997 9.8839 5.4499 0.4142
EFE-184 CTRP2 8.1078 9.5354 5.5806 0.1771
HEC-50B CTRP2 8.4575 22.4723 -0.2555 19.4915
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR10TKB CTRP2 7.2331 8.7165 5.5208 0.7134
786-O CTRP2 7.3274 10.9836 4.5448 4.5258
ACHN CTRP2 7.3895 9.2246 5.386 1.0134
KMRC-2 CTRP2 7.5201 9.1484 5.4818 0.6786
KMRC-1 CTRP2 7.6329 8.9844 5.5952 0.2986
UO-31 CTRP2 7.7212 15.2022 2.7766 10.65
Caki-2 CTRP2 7.7265 12.6384 4.0219 5.7415
VMRC-RCZ CTRP2 7.8472 12.4119 4.2085 4.8479
Caki-1 CTRP2 7.9531 10.9749 4.9294 2.0416
RCC10RGB CTRP2 7.9893 9.2404 5.6404 0.1226
KMRC-3 CTRP2 8.5066 10.2343 5.4824 0.2238
TUHR14TKB CTRP2 8.5826 21.6918 0.2221 27.1873
VMRC-RCW CTRP2 8.6757 10.2027 5.5548 0.1039
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LS123 CTRP2 6.5559 8.1176 5.3969 1.8785
GP2d CTRP2 6.6583 9.625 4.7364 4.4204
SW1417 CTRP2 6.961 9.5772 4.9711 3.0188
NCI-H716 CTRP2 7.0265 9.3954 5.0996 2.4277
T84 CTRP2 7.1619 9.3139 5.2204 1.809
HT-55 CTRP2 7.2706 11.7704 4.1277 5.9702
SNU-C4 CTRP2 7.3471 8.9351 5.4862 0.7349
HCC-56 CTRP2 7.4618 8.5478 5.6879 0.182
SNU-C1 CTRP2 7.5792 15.3206 2.6149 11.4964
RKO CTRP2 7.6474 11.4066 4.5524 3.7675
SW948 CTRP2 7.7502 9.0122 5.6317 0.1915
NCI-H747 CTRP2 7.7714 18.3804 1.2499 16.0663
SW620 CTRP2 7.8848 13.773 3.5855 7.2437
RCM-1 [Human ESC] CTRP2 7.9273 9.3784 5.5678 0.2471
COLO 678 CTRP2 7.9345 17.6936 1.7101 14.2277
LS1034 CTRP2 8.028 9.4856 5.5681 0.2168
HCT 15 CTRP2 8.0457 9.5782 5.5414 0.2755
C2BBe1 CTRP2 8.0529 10.0844 5.3523 0.6645
COLO 320 CTRP2 8.0588 12.9915 4.0718 5.1064
SNU-407 CTRP2 8.0633 9.7954 5.4681 0.3907
MDST8 CTRP2 8.0717 9.191 5.6866 0.0629
SNU-503 CTRP2 8.0852 9.9935 5.4019 0.5271
HCT 8 CTRP2 8.2138 9.4958 5.6329 0.0933
CW-2 CTRP2 8.4313 10.0982 5.5024 0.2129
SNU-61 CTRP2 8.4438 10.1981 5.4714 0.2572
CL-11 CTRP2 8.6157 10.293 5.5022 0.1722
LoVo CTRP2 8.8352 10.5466 5.4937 0.1423
SNU-C5 CTRP2 8.9415 10.6034 5.512 0.1082
NCI-H508 CTRP2 9.2733 19.602 1.7312 12.1237
KM12 CTRP2 9.5938 20.4086 1.5617 12.2457
SNU-1033 CTRP2 12.3714 34.5624 -3.3481 21.1305
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PLC/PRF/5 CTRP2 6.0837 6.9681 5.6149 1.7308
JHH-4 CTRP2 6.7663 8.5337 5.3376 1.8322
SNU-886 CTRP2 6.8908 9.189 5.1092 2.9645
JHH-2 CTRP2 6.9837 10.6967 4.447 5.1031
JHH-6 CTRP2 7.0237 8.0156 5.7064 0.3254
SNU-475 CTRP2 7.0377 10.4065 4.6254 4.2979
SNU-423 CTRP2 7.3627 11.8719 4.1427 5.7739
SK-HEP-1 CTRP2 7.4636 8.972 5.5264 0.545
HuH-6 CTRP2 7.4807 14.3738 3.0076 10.1353
JHH-1 CTRP2 7.5321 8.9854 5.552 0.4418
SNU-449 CTRP2 7.7554 10.7844 4.9028 2.3318
HLF CTRP2 7.8472 9.2055 5.5994 0.2171
JHH-5 CTRP2 8.0349 15.1138 3.0423 9.7796
Hep-G2 CTRP2 8.0523 9.5908 5.5394 0.2579
HuH-1 CTRP2 8.1511 9.5945 5.5759 0.1737
SNU-761 CTRP2 8.2354 21.4294 0.0928 18.875
SNU-398 CTRP2 8.2578 9.964 5.484 0.2908
SNU-387 CTRP2 9.8226 21.5917 1.1494 13.2706
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COR-L88 CTRP2 0.2117 66.2171 -29.0309 48.6158
NCI-H446 CTRP2 6.2111 8.491 4.9571 4.2584
KNS-62 CTRP2 6.3269 7.6627 5.4569 1.9747
NCI-H1105 CTRP2 6.3509 8.097 5.261 2.7466
DMS 53 CTRP2 6.4742 8.6085 5.1005 3.211
COLO 668 CTRP2 6.6501 9.8244 4.6324 4.8634
LK2 CTRP2 6.7147 8.1044 5.5049 1.2537
HCC4006 CTRP2 6.8362 9.0628 5.1331 2.7334
NCI-H1341 CTRP2 6.8434 8.4438 5.4271 1.5015
NCI-H1092 CTRP2 6.8638 8.9243 5.2166 2.3407
NCI-H522 CTRP2 6.8679 8.619 5.3614 1.6165
SW1573 CTRP2 7.003 9.9685 4.8123 3.5946
NCI-H838 CTRP2 7.0663 8.5954 5.4862 1.0321
NCI-H1184 CTRP2 7.1205 13.9612 2.9431 10.9827
IA-LM CTRP2 7.123 9.0469 5.3182 1.4934
DV-90 CTRP2 7.1387 9.3247 5.2016 1.9048
NCI-H1573 CTRP2 7.1726 8.8686 5.4247 1.0724
VMRC-LCD CTRP2 7.1767 9.1313 5.3113 1.463
NCI-H23 CTRP2 7.1895 10.091 4.8773 3.0858
LUDLU-1 CTRP2 7.1897 10.1535 4.8479 3.2005
LCLC-97TM1 CTRP2 7.221 11.2505 4.3447 5.1658
NCI-H2087 CTRP2 7.2221 10.2112 4.8417 3.1827
NCI-H1568 CTRP2 7.2256 10.1824 4.8575 3.3477
EPLC-272H CTRP2 7.2361 9.9929 4.9528 2.7336
HCC1438 CTRP2 7.3446 11.0847 4.5081 4.3362
DMS 454 CTRP2 7.3656 10.1769 4.9479 2.5964
NCI-H1339 CTRP2 7.3671 9.5595 5.2283 1.566
RERF-LC-MS CTRP2 7.3809 9.8918 5.0874 2.0586
COR-L105 CTRP2 7.3942 10.1263 4.9885 2.4103
NCI-H1694 CTRP2 7.4045 8.7038 5.6056 0.3764
NCI-H2110 CTRP2 7.4346 10.7777 4.7117 3.4181
COR-L95 CTRP2 7.4456 8.9678 5.5198 0.616
LC-1/sq-SF CTRP2 7.4544 9.5915 5.2623 1.366
NCI-H2170 CTRP2 7.4856 9.3026 5.4018 0.8886
DMS 114 CTRP2 7.5158 9.5326 5.3201 1.1215
NCI-H810 CTRP2 7.5317 8.897 5.5859 0.3617
HCC2935 CTRP2 7.5388 10.1704 5.0536 2.014
NCI-H2444 CTRP2 7.5552 35.6443 -7.5161 33.4834
NCI-H2196 CTRP2 7.5589 9.4018 5.3968 0.9135
NCI-H1355 CTRP2 7.5726 10.6081 4.8753 2.6303
Lu-65 CTRP2 7.5727 14.7675 2.8817 10.4798
EKVX CTRP2 7.5855 10.924 4.738 3.1323
NCI-H1915 CTRP2 7.5872 9.2226 5.4831 0.5876
PC-14 CTRP2 7.5893 12.0388 4.2164 5.1597
T3M-10 CTRP2 7.6005 9.621 5.326 1.0354
NCI-H647 CTRP2 7.6275 10.1343 5.1194 1.694
NCI-H1944 CTRP2 7.6337 10.5369 4.9436 2.312
A-549 CTRP2 7.6341 9.9694 5.1948 1.4317
Calu-1 CTRP2 7.6344 9.4275 5.4226 0.7243
NCI-H1755 CTRP2 7.6567 9.7475 5.3012 1.0693
NCI-H1651 CTRP2 7.6625 10.1689 5.1234 1.6474
NCI-H226 CTRP2 7.6791 16.7882 1.9666 13.7383
SK-MES-1 CTRP2 7.7057 10.3168 5.0822 1.8778
Calu-6 CTRP2 7.7769 10.1565 5.1895 1.3272
Sq-1 CTRP2 7.8474 9.1881 5.6058 0.2064
NCI-H2081 CTRP2 7.8545 13.2001 3.8394 6.2857
NCI-H1703 CTRP2 7.8903 15.3763 2.813 10.9448
NCI-H1563 CTRP2 7.9083 9.8087 5.3962 0.6319
DMS 273 CTRP2 7.9447 17.0018 2.0574 12.9777
RERF-LC-Ad2 CTRP2 7.9474 10.6169 5.0816 1.535
NCI-H2228 CTRP2 7.9497 17.8725 1.6333 14.47
NCI-H1793 CTRP2 8.0322 9.6405 5.5132 0.3123
LOU-NH91 CTRP2 8.0759 9.8386 5.4571 0.4087
NCI-H1869 CTRP2 8.1117 10.0849 5.378 0.5706
NCI-H1373 CTRP2 8.1271 10.464 5.2347 0.9353
NCI-H841 CTRP2 8.1785 9.81 5.509 0.2718
HCC1195 CTRP2 8.1894 9.6495 5.5708 0.1721
ChaGo-K-1 CTRP2 8.2024 13.2524 4.0409 5.045
NCI-H520 CTRP2 8.2226 13.4235 3.9737 5.2772
NCI-H2122 CTRP2 8.2506 9.8827 5.5107 0.2476
NCI-H1623 CTRP2 8.2665 11.6054 4.8245 2.1097
NCI-H1666 CTRP2 8.2903 10.142 5.4314 0.3779
NCI-H2029 CTRP2 8.2921 9.5107 5.6552 0.0637
NCI-H322 CTRP2 8.2998 9.7485 5.5767 0.1413
NCI-H2126 CTRP2 8.3462 9.4285 5.7007 0.0305
NCI-H889 CTRP2 8.3663 19.346 1.2154 15.2102
NCI-H1792 CTRP2 8.3776 10.2428 5.4293 0.3509
LXF 289 CTRP2 8.3849 12.0584 4.6911 2.455
SK-LU-1 CTRP2 8.401 13.6265 3.991 4.9915
NCI-H2023 CTRP2 8.6185 10.427 5.456 0.2352
NCI-H1650 CTRP2 8.691 11.7969 4.9599 1.347
EBC-1 CTRP2 8.9367 10.9638 5.385 0.2617
NCI-H2085 CTRP2 8.9637 10.7796 5.4595 0.1587
NCI-H2342 CTRP2 8.9953 16.5618 2.9946 7.9929
HOP-92 CTRP2 9.6808 23.3089 0.2228 16.284
SW1271 CTRP2 10.2313 22.0477 1.2055 12.5407
NCI-H460 CTRP2 10.4118 23.7493 0.514 14.417
HOP-62 CTRP2 11.6053 23.2893 1.4977 9.9366
NCI-H661 CTRP2 12.3123 25.4082 0.9535 10.7955
NCI-H1435 CTRP2 12.5239 29.73 -0.9316 15.6699
Hs 888.Lu CTRP2 8.3246 10.5023 5.3089 0.6305
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 6.9756 9.6401 4.9508 3.0794
P-STS CTRP2 7.8119 9.401 5.5124 0.4011
SYO-1 CTRP2 7.9627 9.4052 5.5719 0.2293
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.6195 9.5932 5.3472 0.9558
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 7.7194 8.9947 5.6261 0.2099
Yamato-SS CTRP2 7.7273 9.2184 5.5462 0.3636
BT-12 CTRP2 6.8876 8.0197 5.6394 0.6106
GCT CTRP2 7.0719 9.5041 5.0775 2.4563
TE 441.T CTRP2 7.203 8.6395 5.5379 0.6836
G-401 CTRP2 7.2344 11.1393 4.4075 4.893
HT-1080 CTRP2 7.3344 11.5452 4.2807 5.6475
SK-LMS-1 CTRP2 7.422 9.099 5.4551 0.7742
Hs 729.T CTRP2 7.4348 14.2733 3.0233 10.8546
MES-SA CTRP2 7.4772 9.2239 5.4304 0.8085
BT-16 CTRP2 7.5704 8.8861 5.6064 0.3004
RKN CTRP2 7.6793 9.0914 5.5741 0.3239
A-204 CTRP2 7.685 11.8585 4.3645 4.4496
SW982 CTRP2 7.7217 8.9705 5.6358 0.193
TTC-709 CTRP2 7.7548 9.3369 5.5126 0.4265
G-402 CTRP2 7.8182 10.4646 5.0788 1.6564
TE 617.T CTRP2 7.8303 9.6099 5.4395 0.6062
SK-UT-1 CTRP2 7.8504 15.1036 2.9174 9.9063
Tm87-16 CTRP2 7.9172 9.3618 5.5699 0.2466
KYM-1 CTRP2 7.9875 11.5082 4.7116 2.7791
RD CTRP2 8.2216 12.8744 4.2282 4.3093
Rh18 CTRP2 8.3659 9.6269 5.6416 0.0664
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 8.0926 9.8193 5.4712 0.3729
JHOM-1 CTRP2 6.5014 8.7179 5.0667 3.3071
OV-90 CTRP2 6.5689 7.9569 5.482 1.5224
OV7 CTRP2 6.6683 12.1743 3.4826 9.5903
TOV-21G CTRP2 6.7119 8.8872 5.1335 2.716
MCAS CTRP2 6.7252 11.161 4.0289 7.2395
OV56 CTRP2 6.9855 8.5813 5.4478 1.1705
A2780 CTRP2 7.0249 9.2338 5.1739 2.1429
TOV-112D CTRP2 7.1473 9.831 4.9723 2.7691
OC 314 CTRP2 7.3354 13.1633 3.4951 8.4283
TYK-nu CTRP2 7.4916 10.6115 4.8247 2.9146
COV434 CTRP2 7.5587 10.788 4.7843 2.9883
OAW42 CTRP2 7.5861 8.562 5.7297 0.0905
FU-OV-1 CTRP2 7.7391 16.3083 2.2472 12.6171
COV644 CTRP2 7.8021 11.2777 4.7069 2.9986
HEY A8 CTRP2 7.9043 9.3683 5.5624 0.2643
OVCAR-4 CTRP2 7.9189 14.4921 3.2623 8.4627
COV362 CTRP2 7.9283 9.9091 5.3654 0.7005
Caov-3 CTRP2 7.9546 9.3772 5.5789 0.22
SNU-840 CTRP2 8.0311 9.8145 5.4474 0.4486
SK-OV-3 CTRP2 8.065 9.3015 5.6466 0.102
EFO-21 CTRP2 8.1159 13.6455 3.8005 6.0837
IGROV-1 CTRP2 8.1279 11.7493 4.6842 2.7317
JHOS-2 CTRP2 8.2211 9.8787 5.5007 0.2933
OAW28 CTRP2 8.336 12.5747 4.4335 3.4182
OVCAR-5 CTRP2 8.3424 9.8493 5.5571 0.1574
EFO-27 CTRP2 8.3956 10.3215 5.4074 0.3863
OVK18 CTRP2 8.4191 9.9103 5.5638 0.1347
RMG-I CTRP2 8.5992 10.4827 5.4287 0.2828
OVCAR-8 CTRP2 13.5236 25.0525 1.8119 7.0533
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 6.5027 11.1774 3.8491 8.3704
JL-1 CTRP2 7.2565 9.0201 5.4039 1.0673
IST-Mes1 CTRP2 7.3156 10.4864 4.7724 3.3331
NCI-H2452 CTRP2 7.8148 9.9053 5.3136 0.9165
NCI-H2052 CTRP2 8.7244 10.3903 5.5079 0.1452
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 6.8462 9.7173 4.8256 3.7665
PaCa-3 CTRP2 7.6528 9.7777 5.2865 1.1183
DU145 CTRP2 7.8595 12.5187 4.1661 4.997
VCaP CTRP2 8.4597 9.9499 5.5647 0.1266
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 7.6898 13.347 3.6568 7.2429
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 6.7467 8.1897 5.4851 1.2911
HGC-27 CTRP2 6.7872 8.9197 5.1687 2.4698
HuG1-N CTRP2 7.1666 10.8381 4.506 4.5936
NCC-StC-K140 CTRP2 7.1763 14.047 2.9428 11.6467
SNU-1 CTRP2 7.1971 9.7039 5.0627 2.3601
ECC10 CTRP2 7.2916 9.4463 5.236 1.6144
SH-10-TC CTRP2 7.3172 11.8557 4.119 5.9365
MKN7 CTRP2 7.3616 9.8548 5.0928 2.0599
MKN74 CTRP2 7.3902 11.0977 4.5321 4.1794
Hs 746.T CTRP2 7.4456 9.2554 5.4016 0.9197
SNU-601 CTRP2 7.5676 9.1446 5.5052 0.5409
OCUM-1 CTRP2 8.0223 10.1502 5.3123 0.787
NUGC-3 CTRP2 8.0811 9.601 5.547 0.2364
Fu97 CTRP2 8.0858 9.9403 5.4226 0.4796
SNU-216 CTRP2 8.1072 9.9741 5.4188 0.4786
IM95 CTRP2 8.1969 9.8151 5.5144 0.2571
LMSU CTRP2 9.1387 15.5788 3.5427 5.7896
KE-39 CTRP2 9.2178 16.3061 3.2553 6.7512
SNU-685 CTRP2 7.0835 8.9754 5.3275 1.5013
SNG-M CTRP2 7.4807 11.5987 4.3538 4.7632
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ML-1 [Human leukemia] CTRP2 0.8594 92.921 -41.7869 48.6197
FTC-133 CTRP2 7.0803 9.6022 5.0369 2.603
SW579 CTRP2 7.5491 9.2655 5.448 0.7602
FTC-238 CTRP2 7.5964 10.1378 5.1006 1.7892
TT2609-C02 CTRP2 7.8636 10.6837 5.008 1.8555
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-2 CTRP2 6.6887 9.9037 4.6218 4.8447
PE/CA-PJ49 CTRP2 6.9506 8.6583 5.3931 1.5086
FaDu CTRP2 7.2733 9.0598 5.3957 1.1598
BICR 22 CTRP2 7.2809 8.92 5.4594 0.8669
PE/CA-PJ15 CTRP2 7.3277 9.1306 5.394 1.0387
PE/CA-PJ34 (clone C12) CTRP2 7.3857 10.6587 4.7363 3.3841
SCC-9 CTRP2 7.5319 14.0855 3.1861 9.3513
SCC-4 CTRP2 7.5546 9.5987 5.3121 1.1156
BICR 31 CTRP2 7.6271 11.128 4.6693 3.344
CAL-27 CTRP2 7.7208 8.9013 5.6603 0.1546
BICR 6 CTRP2 7.7901 9.2385 5.5646 0.3002
BICR 16 CTRP2 7.8329 9.3606 5.5364 0.3408
BICR 56 CTRP2 7.972 9.6975 5.4671 0.4311
BICR 18 CTRP2 7.983 10.1759 5.2835 0.8908
CAL-33 CTRP2 8.0525 9.733 5.4871 0.3562
YD-8 CTRP2 8.0749 12.6651 4.2344 4.4619
PE/CA-PJ41 (clone D2) CTRP2 8.2538 9.8644 5.5185 0.234
HSC-4 CTRP2 8.4329 12.853 4.3645 3.5656
SCC-25 CTRP2 8.5854 10.9111 5.2638 0.612
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BC-3C CTRP2 6.5618 7.8702 5.5183 1.3893
HT-1197 CTRP2 6.7053 8.5046 5.3119 2.0126
J82 CTRP2 6.7929 9.2373 5.0205 3.0556
UM-UC-1 CTRP2 6.9798 9.5074 5.0166 2.8131
UM-UC-3 CTRP2 7.3173 9.4851 5.2333 1.5981
RT-4 CTRP2 7.5313 11.3097 4.5238 4.0263
T24 CTRP2 7.5662 11.718 4.3536 4.6485
RT-112 CTRP2 7.7443 9.5993 5.4047 0.7049
SCaBER CTRP2 7.7707 9.8352 5.3212 0.9249
647V CTRP2 7.9783 9.309 5.6123 0.1623
U-BLC1 CTRP2 8.6496 15.6779 3.1874 7.7269
KMBC-2 CTRP2 10.2819 19.9711 2.216 9.1448
HT-1376 CTRP2 11.1085 33.0491 -3.5055 22.9969
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.3063 9.2452 5.333 1.2612

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 484).